CROSS-LINKED CATION EXCHANGE POLYMERS, COMPOSITIONS AND USE IN THE TREATMENT OF HYPERKALAMIEMIA

Abstract

The present invention is directed to cross-linked cation exchange polymers comprising a fluorine group and an acid group, pharmaceutical compositions of these polymers, compositions of a linear polyol and a salt of such a polymer. Cross-linked cation exchange polymers having beneficial physical properties, including combinations of particle size, particle shape, particle size distribution, viscosity, yield strength, compressibility, surface morphology, and / or swelling ratio are also described. These polymers and compositions are useful for binding potassium in the gastrointestinal tract.