BENZIMIDAZOLE DERIVATIVES AS MODIFIERS OF RETINOID-LINKED ORPHAN RECEPTOR GAMMA (RORγ) AND THEIR PHARMACEUTICAL USES

CY1126202T1Undetermined Publication Date: 2026-07-31JIANGSU HENGRUI MEDICINE CO LTD

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Patent Information

Application Number: CY20231100333T
Authority / Receiving Office: CY · CY
Patent Type: Patents
Current Assignee / Owner
Priority Date: 2018-05-03
Filing Date: 2023-07-13
Publication Date: 2026-07-31
Estimated Expiration: 2043-07-13

Application Information

Patent Timeline

03 May 2018

Priority

13 Jul 2023

Application

CY20231100333T

31 Jul 2026

Publication

CY1126202T1

IPC: C07D235/06; A61K31/4184; A61K31/454; A61K31/5377; A61P29/00; A61P35/00; A61P37/00; C07C317/22; C07D211/38; C07D235/10; C07D235/12; C07D235/16; C07D401/04; C07D409/04; C07D413/12

CPC: C07D235/06; C07D211/38; C07D401/04; A61P29/00; A61P37/04; A61P35/00; A61P19/02; A61P17/06

Inventors: YAN Yinfa; ZHANG Minsheng

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Benzimidazole derivative Disease

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Abstract

The present invention relates to benzimidazole derivatives of formula (I) as inhibitors of the retinoid-binding orphan receptor gamma (RORγ) protein, pharmaceutical compositions containing the compounds, methods of preparing them, and the use of the compounds as therapeutic agents for the treatment of diseases or disorders mediated by RORγ.

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