Manufacturing device for increasing the activity of redworm dry powder

Abstract

A manufacturing device for increasing the activity of redworm dry powder, comprising: a cleaning device designed to hold a cleaning solution for cleaning live redworms and stimulating them to vomit sand; a freezing device equipped with a liquid nitrogen supply unit to rapidly freeze the purified redworms and thus preserve the activity of the substances contained in the redworms; a hydrolysis unit comprising a culture vessel used to heat and thaw the frozen redworms in order to accelerate the autologous hydrolysis and liquefaction of the redworms, thus obtaining a solid-liquid mixture of hydrolyzed solid components and raw material liquid; a centrifugal filter device comprising a centrifuge and a filter membrane, wherein the filter membrane is arranged in the centrifuge and serves to separate the solid components and the raw material liquid; a sterilization device used to filter the raw material liquid in order to remove the bacteria commonly found in the raw material liquid; A freeze-drying apparatus comprising a drying chamber, a refrigeration and air conditioning unit and an air handling unit, wherein the drying chamber serves to hold the raw material liquid, the refrigeration and air conditioning unit is continuously connected to the air handling unit and the air handling unit serves to introduce the low-temperature air supplied by the refrigeration and air conditioning unit into the drying chamber in order to process the raw material liquid into a redworm dried preparation by freeze-drying, wherein the drying chamber has a release opening that discharges the moist air released from the raw material liquid; A cryogenic grinding device comprising a grinding chamber, a low-temperature air supply unit, and a grinding structure, wherein the grinding chamber has a material inlet and a material outlet such that the redworm dry preparation is introduced into the grinding chamber via the material inlet and the redworm dry powder obtained by grinding is discharged from the grinding chamber via the material outlet, wherein the low-temperature air supply unit is continuously connected to the grinding chamber and supplies the grinding chamber with liquid nitrogen to create a low-temperature environment in the grinding chamber, wherein the grinding structure is arranged in the grinding chamber and serves to grind the redworm dry preparation into redworm dry powder; and a conveying device that is continuously connected to the cleaning device, the freezing device, the hydrolysis unit, the centrifugal filter device, the sterilization device, the freeze-drying device and the cryogenic grinding device.

Description

Field of the invention

[0001] The present invention relates to a redworm powder and, more particularly, to a manufacturing device for increasing the activity of redworm dry powder. State of the art

[0002] Using redworms as raw materials, freeze-dried redworm dry powder can convert the fibrin contained in the blood into plasminogen, thereby achieving high fibrinolytic activity. Redworm dry powder can be directly dissolved and plays a role in the role of fibrin in blood coagulation. Freeze-dried redworm powder is known to be used to treat vascular diseases such as cerebral infarction, ischemic cerebrovascular disease, diabetes, hypertension, and more. It can also be used to prevent thrombosis, inhibit fibrinogenase, and increase platelet aggregation. In addition, redworm dry powder contains proteolytic enzymes derived from edible redworms themselves, which exhibit extremely strong fibrin-dissolving activity.

[0003] In the production of existing red worm dry powders, the powdered material obtained by crushing the red worms is dried with hot air, and the product obtained by hot air drying is then subjected to high-temperature sterilization. This process results in the enzyme losing activity, regardless of whether the process used is hot air drying or high-temperature sterilization. Object of the invention

[0004] The main object of the present invention is to provide a manufacturing device that increases the activity of red worm dry powder.

[0005] To achieve the above object, the present invention uses the following technical solutions: a manufacturing device for increasing the activity of red worm dry powder, comprising: a cleaning device designed to hold a cleaning solution to clean live redworms and stimulate them to vomit sand; a freezing facility equipped with a liquid nitrogen supply device to quickly freeze the purified redworms and thus preserve the activity of the substances contained in the redworms; a hydrolysis unit comprising a culture container used to heat and thaw the frozen redworms to accelerate the autologous hydrolysis and liquefaction of the redworms and thus obtain a solid-liquid mixture of hydrolyzed solid components and raw material liquid; a centrifugal filter device comprising a centrifuge and a filter membrane, the filter membrane being arranged in the centrifuge and serving to separate the solid components and the raw material liquid; a sterilization device used to filter the raw material liquid to remove bacteria commonly contained in the raw material liquid; a freeze-drying device comprising a drying chamber, a refrigeration and air-conditioning unit, and an air-guiding device, wherein the drying chamber serves to contain the raw material liquid, the refrigeration and air-conditioning unit is continuously connected to the air-guiding device, and the air-guiding device serves to introduce the low-temperature air supplied by the refrigeration and air-conditioning unit into the drying chamber to process the raw material liquid into a red worm dry preparation by freeze-drying, wherein the drying chamber has a release opening that discharges the moist air released from the raw material liquid; a cryogenic grinding device comprising a grinding chamber, a low-temperature air supply device, and a grinding structure, wherein the grinding chamber has a material inlet and a material outlet such that the red worm dry preparation is introduced into the grinding chamber via the material inlet and the red worm dry powder obtained by grinding is discharged from the grinding chamber via the material outlet, wherein the low-temperature air supply device is continuously connected to the grinding chamber and supplies the grinding chamber with liquid nitrogen to create a low-temperature environment in the grinding chamber, wherein the grinding structure is arranged in the grinding chamber and serves to grind the red worm dry preparation into red worm dry powder; and a conveyor device that is continuously connected to the cleaning device, the freezing device, the hydrolysis unit, the centrifugal filter device, the sterilization device, the freeze-drying device and the cryogenic grinding device.

[0006] The process of both drying and solidifying the raw material liquid into red worm dry preparation and grinding the red worm dry preparation into red worm dry powder is carried out under low temperatures in order to minimize the loss of activity of the red worm dry powder caused by the influence of the process temperature and thus increase the retained activity. Brief description of the drawings Fig. 1 shows a schematic representation of the system configuration according to a preferred embodiment of the present invention; Fig. 2 shows a sectional view of the freeze-drying device according to the preferred embodiment of the present invention; Fig. 3 shows a sectional view of the cryogenic milling device according to the preferred embodiment of the present invention in use for performing cryogenic milling; Fig. Figure 4 shows a flow chart for producing the red worm dry powder according to the preferred embodiment of the present invention. Detailed description of the embodiment

[0007] Reference is made to the figures, which show a preferred embodiment of the inventive device for increasing the activity of red worm dry powder. The following description only illustrates exemplary embodiments of the invention and is not intended to limit the claims.

[0008] It is based on the Fig. 1 to 3. The preferred embodiment of the production device for increasing the activity of red worm dry powder comprises a cleaning device 10, a freezing device 20, a hydrolysis unit 30, a centrifugal filter device 40, a sterilization device 50, a freeze-drying device 60, a cryogenic grinding device 70 and a conveyor device 80, wherein the conveyor device 80 is continuously connected to the cleaning device 10, the freezing device 20, the hydrolysis unit 30, the centrifugal filter device 40, the sterilization device 50, the freeze-drying device 60 and the cryogenic grinding device 70, whereby the materials to be processed are conveyed by means of the conveyor device 80 successively to the cleaning device 10, the freezing device 20, the hydrolysis unit 30, the centrifugal filter device 40, the sterilization device 50,the freeze-drying device 60 and the cryogenic grinding device 70. The materials include redworms and various semi-finished products obtained during the manufacturing process of the redworm dry powder 94.

[0009] The cleaning device 10 serves to hold a cleaning solution to clean live redworms and stimulate them to vomit sand.

[0010] The freezing device 20 is equipped with a liquid nitrogen supply device (not shown) to quickly freeze the purified redworms and thus preserve the activity of the substances contained in the redworms.

[0011] The hydrolysis unit 30 comprises a culture container (not shown) which serves to warm and thaw the redworms frozen by the freezing device 20 in order to accelerate the autologous hydrolysis and liquefaction of the redworms and thus to obtain a solid-liquid mixture of hydrolyzed solid components and raw material liquid.

[0012] The centrifugal filter device 40 comprises a centrifuge (not shown) and a filter membrane (not shown), wherein the filter membrane is arranged in the centrifuge, the centrifuge centrifuges the solid-liquid mixture to separate the solid components of the solid-liquid mixture from the liquid raw material liquid, and the filter membrane filters the raw material liquid to separate the impurities from the raw material liquid.

[0013] The sterilization device 50 is a sterilization filter that uses a filter membrane (not shown) with a pore size of 0.2 µm to filter the raw material liquid and thus remove the bacteria often contained in the raw material liquid.

[0014] The freeze-drying device 60 comprises a drying chamber 62, a refrigeration and air-conditioning unit 64, and an air-guiding device 66. The drying chamber serves to hold the raw material liquid. In the present embodiment, the drying chamber 62 is equipped with a plurality of disc-shaped containers 63, each of which serves to hold the raw material liquid. The refrigeration and air-conditioning unit 64 is continuously connected to the air-guiding device 66. The air-guiding device 66 serves to introduce the low-temperature air supplied by the refrigeration and air-conditioning unit 64 into the drying chamber 62 in order to process the raw material liquid into a red worm dry preparation 92 by freeze-drying. The drying chamber 62 has a release port 68 for discharging the moist air released from the raw material liquid, thus maintaining a low-humidity environment in the drying chamber 62.

[0015] The cryogenic grinding device 70 comprises a grinding chamber 72, a low-temperature air supply device 74, and a grinding structure 76, wherein the grinding chamber 72 has a material inlet 722 and a material outlet 724 such that the red worm dry preparation 92 is introduced into the grinding chamber 72 via the material inlet 722 and the red worm dry powder 94 obtained by grinding is led out of the grinding chamber 72 via the material outlet 724, wherein the low-temperature air supply device 74 is continuously connected to the grinding chamber 72 and supplies the grinding chamber 72 with liquid nitrogen to create a low-temperature environment in the grinding chamber 72, wherein the grinding structure 76 is arranged in the grinding chamber 72 and serves to grind the red worm dry preparation 92 into red worm dry powder 94.

[0016] It will be Fig.4, which shows a method for producing the red worm dry powder 94 according to a preferred embodiment. The method comprises the following steps, which must be performed sequentially: Cleaning: The cleaning device 10 uses a cleaning solution to clean the outer surface of the live redworms and stimulate the redworms to vomit sand. After cleaning, the redworms are dried, and then the dried redworms are conveyed to the freezing device 20 by the conveyor device 80. Freezing: The freezing device 20 uses the liquid nitrogen provided by the liquid nitrogen supply device to quickly freeze the redworms treated after the cleaning step at -196 °C, so that the redworms remain shelf-stable and do not spoil. Hydrolysis: The redworms treated by the freezing device 20 are thawed and placed in the culture container of the hydrolysis unit 30. Using the enzymes produced by the redworms themselves, the redworms are automatically hydrolyzed and liquefied by temperature control within a suitable range for enzymatic hydrolysis to obtain a solid-liquid mixture of the hydrolyzed solid components and the raw material liquid. The solid-liquid mixture is then conveyed to the centrifugal filter device 40 by the conveying device 80. Solid-liquid separation: The centrifuge centrifuges the solid-liquid mixture at an ambient temperature of 4°C, separating the solid components of the solid-liquid mixture from the raw material liquid. The filter membrane filters the raw material liquid, removing solid impurities or foreign matter entrained in the raw material liquid to obtain a clear, impurity-free liquid. The raw material liquid is then conveyed to the sterilization device 50 by the conveying device 80. Sterilization: The sterilization device 50 uses a filter membrane with a pore size of 0.2 µm to filter the raw material liquid, remove the bacteria commonly present in the raw material liquid, and eliminate the bacterial contamination that occurs in the raw material liquid during the hydrolysis step and the solid-liquid separation step. The sterilized raw material liquid is then conveyed to the freeze-drying device 60 by the conveying device 80. Freeze-drying: Containers 63 containing the raw material liquid are placed in the drying chamber 62. The refrigeration and air-conditioning unit 64 provides cold dry air, which is introduced into the drying chamber 62 through the air guide device 66. The cold air flows through the drying chamber 62, creating a low-temperature environment in the drying chamber 62. The flowing cold air is blown onto the raw material liquid and absorbs the moisture in the raw material liquid, thereby converting the raw material liquid into a red worm dry preparation 92 through freeze-drying. The moist air that has absorbed the moisture released from the raw material liquid is discharged from the drying chamber 62 through the release port 68, thereby maintaining the drying chamber 62 at a low temperature and in a relatively dry state.The red worm dry preparation 92 is then conveyed to the cryogenic grinding device 70 by means of the conveying device 80. Cryogenic grinding: The low-temperature air supply device 74 supplies the grinding chamber 72 with liquid nitrogen, creating an ambient temperature of -196°C in the grinding chamber 72. The red worm dry preparation 92 is introduced into the grinding chamber 72 via the material inlet 722 and ground by the grinding structure 76 in a low-temperature environment of -196°C, so that the red worm dry preparation 92 is pulverized into red worm dry powder 94. The red worm dry powder 94 is then discharged from the cryogenic grinding device 70 via the material outlet 724.

[0017] The freeze-drying device 60 processes the raw material liquid into red worm dry preparation 92 by freeze-drying, and the cryogenic grinding device 70 grinds the red worm dry preparation 92 into red worm dry powder 94 under low-temperature conditions, thereby keeping the red worm dry preparation 92 and the red worm dry powder 94 at low temperatures.

[0018] The process of both drying and solidifying the raw material liquid into redworm dry preparation 92 and grinding the redworm dry preparation 92 into redworm dry powder 94 is carried out at low temperatures, thereby improving the activity of the produced redworm dry powder 94 and avoiding exposure of the redworm dry preparation 92 or redworm dry powder 94 to high temperatures. Furthermore, the quality deterioration of the material, intermediate products, and final product during the production process of the redworm dry powder 94 can be prevented, thereby improving the quality and activity of the redworm dry powder 94, thus preserving the nutritional values ​​and usability of the redworms. With the invention, the content of nutrients and active substances in the redworm dry powder 94 can be significantly increased.

Claims

[1] A manufacturing device for increasing the activity of red worm dry powder, comprising: a cleaning device designed to hold a cleaning solution to clean live redworms and stimulate them to vomit sand; a freezing facility equipped with a liquid nitrogen supply device to quickly freeze the purified redworms and thus preserve the activity of the substances contained in the redworms; a hydrolysis unit comprising a culture container used to heat and thaw the frozen redworms to accelerate the autologous hydrolysis and liquefaction of the redworms and thus obtain a solid-liquid mixture of hydrolyzed solid components and raw material liquid; a centrifugal filter device comprising a centrifuge and a filter membrane, the filter membrane being arranged in the centrifuge and serving to separate the solid components and the raw material liquid; a sterilization device used to filter the raw material liquid to remove bacteria commonly contained in the raw material liquid; a freeze-drying device comprising a drying chamber, a refrigeration and air-conditioning unit, and an air-guiding device, wherein the drying chamber serves to contain the raw material liquid, the refrigeration and air-conditioning unit is continuously connected to the air-guiding device, and the air-guiding device serves to introduce the low-temperature air supplied by the refrigeration and air-conditioning unit into the drying chamber to process the raw material liquid into a red worm dry preparation by freeze-drying, wherein the drying chamber has a release opening that discharges the moist air released from the raw material liquid; a cryogenic grinding device comprising a grinding chamber, a low-temperature air supply device, and a grinding structure, wherein the grinding chamber has a material inlet and a material outlet such that the red worm dry preparation is introduced into the grinding chamber via the material inlet and the red worm dry powder obtained by grinding is discharged from the grinding chamber via the material outlet, wherein the low-temperature air supply device is continuously connected to the grinding chamber and supplies the grinding chamber with liquid nitrogen to create a low-temperature environment in the grinding chamber, wherein the grinding structure is arranged in the grinding chamber and serves to grind the red worm dry preparation into red worm dry powder; and a conveyor device that is continuously connected to the cleaning device, the freezing device, the hydrolysis unit, the centrifugal filter device, the sterilization device, the freeze-drying device and the cryogenic grinding device.

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