Light sheet fluorescence microscope
Patent Information
- Application Number
- DE602019071196
- Authority / Receiving Office
- DE · DE
- Patent Type
- Patents
- Current Assignee / Owner
- Filing Date
- 2019-12-05
- Publication Date
- 2025-06-18
- Estimated Expiration
- 2039-12-05
AI Technical Summary
Existing light sheet fluorescence microscopes lack flexibility in photomanipulation, particularly in configurations like OPM and SCAPE, where simultaneous imaging and manipulation are challenging.
The microscope incorporates an optical system that directs manipulation light through a spatially limited sub-area of the objective's entrance pupil, allowing for flexible adjustment of the manipulation light's direction independently of the light sheet, enabling precise photomanipulation in various experimental setups.
This configuration allows for efficient and flexible photomanipulation of specimens, enabling precise control over the region of interest within the object plane illuminated by the light sheet, and supports a wide range of applications including OPM and SCAPE configurations.