IMPLANTABLE DEVICE AND THERAPEUTIC SYSTEM WITH ACTIVE OXYGENATION
Patent Information
- Authority / Receiving Office
- DE · DE
- Patent Type
- Patents
- Current Assignee / Owner
- Filing Date
- 2022-04-25
- Publication Date
- 2026-04-08
AI Technical Summary
Implantable devices for beta cell replacement therapy face challenges in ensuring sufficient oxygen supply to cells, particularly in large or high-density configurations, leading to cell vulnerability and potential death due to insufficient oxygen diffusion.
The implantable device features a porous container with controlled pore sizes for passive oxygenation and vascularization, promoting oxygen transfer through an exterior surface, and in some embodiments, includes an active oxygenation mechanism using oxygen-generating substances to supplement oxygen supply during the vascularization period.
Ensures sufficient oxygen delivery to beta cells for viability and therapeutic function, avoiding the need for supplemental energy sources and maintaining a compact, flexible implant design that facilitates easy placement in the body.