NEW BONE REGENERATION SYSTEM

Abstract

The present invention relates to 1) a bone regeneration kit for a bone defect site in a patient's jawbone, comprising A) a bone regeneration substitute for filling the bone defect and B) a bone regeneration system incorporating a device for maintaining the bone regeneration substitute and, optionally, a covering membrane on said bone defect; 2) such a bone regeneration system; and 3) such a device for maintaining the bone regeneration substitute and, optionally, the covering membrane on said bone defect.

Description

Title of the invention: NEW BONE REGENERATION SYSTEM FIELD OF THE INVENTION

[0001] The present invention relates to the field of devices intended for bone regeneration and, more specifically, to that of the stabilization of endosseous dental implants. PREVIOUS ART

[0002] Conventionally, endosseous implants take the form of an anchoring foot adapted for implantation in a patient's jaw bone, which anchoring foot most often corresponds to an anchoring screw.

[0003] An example of such implants is given in patent application US 2003 / 232308 in which an anchoring foot (base) intended to be positioned in a complementary shaped housing prepared in the patient's jawbone also has a collar (platform) extending from the base and with which it therefore forms a single piece. Now, this anchoring foot most often cooperates with an external abutment which is intended to be fixed in the anchoring foot and which will be coupled to a prosthetic connection allowing a crown to be fixed to replace the missing dental element.

[0004] Now, such an implantation can be complicated by the presence of bone defects within the patient's jaw itself. Such bone defects, which can have multiple origins (infectious, tumoral or traumatic), result from a defect in bone healing and correspond to cavities in place of the destroyed bone.

[0005] Faced with such bone defects, it is possible to use biomaterials allowing both the filling of the bone defect and promoting bone healing within it.

[0006] Generally, the biomaterial used consists of either synthetic bone substitute material (for example hydroxyapatite granules) or bone particles. Once the recess corresponding to the bone defect is filled with this biomaterial, this recess is closed by a membrane or a covering plate which makes it possible to direct and contain the growth of this biomaterial, this is called Guided Bone Regeneration (GBR). As examples of such membranes and covering plates, mention may be made of those described in US patent 4,816,339 and in EP patent 2,536,446 B1 respectively.

[0007] Each of these solutions (membrane or cover plate) has its respective advantages and disadvantages.

[0008] The covering membrane, by its structure, allows the passage of nutrients allowing bone regeneration while not being colonized by bone cells. Also, the covering membrane can be simply removed once regeneration is complete without risking weakening or dragging away regenerated bone. Now, the "flexible" nature of this covering membrane makes it difficult to frame the volume of bone regeneration.

[0009] Conversely, the cover plate, due to its rigidity, allows the volume of this regeneration to be optimally guided. Now, the perforation of its structure to allow the passage of nutrients to the regeneration site leads to its colonization by bone cells. As a result, the removal of the cover plate at the end of regeneration is complicated and is likely to affect the integrity of the regenerated bone.

[0010] As for the maintenance of the membrane or covering plate, it is ensured by screws fixed to the bone surrounding the bone defect. Now, and in the case of a moderate-sized bone defect, it can also be ensured, in combination with the anchoring foot of the future dental implant pre-positioned within the bone defect of the patient's jaw, by a screw fixed to said anchoring foot. As for the need for multiple fixation points, it greatly complicates the implementation of these solutions by the practitioner, in addition to increasing the trauma to the already weakened bone of the patient's jaw.

[0011] Also, it is important to develop new bone regeneration solutions, particularly for moderate-sized bone defects, which present simplified implementation for the patient, minimal trauma to the patient's jaw bone, while ensuring the best possible result in terms of bone regeneration at the bone defect site. SUMMARY OF THE INVENTION

[0012] Faced with this problem, the inventor has now developed a new solution adapted to the bone regeneration of moderate-sized bone defects which, apart from the fixation associated with the anchoring foot of the future implant, does not require any fixation in the bone surrounding the bone defect, while framing the volume of bone regeneration in an improved manner. This particularly innovative solution may or may not use a covering membrane.

[0013] In detail, a first object of the invention relates to a bone regeneration kit for a bone defect site in a jaw bone of a patient which comprises:

[0014] A) a bone regeneration substitute allowing the filling of the bone defect and

[0015] B) a bone regeneration system comprising:

[0016] 1) at least one anchoring foot suitable for installation in an endosteal manner in the jaw bone, preferably within the bone defect itself;

[0017] 2) optionally at least one covering membrane, preferably a covering membrane whose surface allows at least the entire bone defect filled by the bone regeneration substitute to be covered;

[0018] 3) at least one device intended to ensure the maintenance of the regeneration substitute bone and, possibly, the covering membrane over said bone defect which comprises:

[0019] 3a) on its face directed towards the bone, at least one external pillar intended to be fixed in the anchor foot, which outer pillar comprises anti-rotational means for inhibiting relative movements of the outer pillar with respect to the anchor foot once the outer pillar is placed in the anchor foot; and

[0020] 3b) on its face opposite the bone, at least one covering piece placed on the bone regeneration substitute and, optionally, on the covering membrane so as to delimit, in combination with said bone regeneration substitute and, optionally, said covering membrane, the volume of bone regeneration at said bone defect site, which covering piece has:

[0021] 3bi) a central part, in the extension of the external pillar, and

[0022] 3bii) at least 2 elongate lateral extensions (7a, 7b) in the extension of this i) central part whose axis intersects perpendicularly the central axis (AA), corresponding to the axis crossing the central part and the 1) at least one anchoring pillar, preferably each elongate lateral extension (7a, 7b) does not include any orifice intended for the positioning of a fixing screw and / or said elongate lateral extensions (7a, 7b) are flexible.

[0023] A second object of the invention relates to a bone regeneration system as described previously.

[0024] A third object of the invention relates to a device intended for maintaining the bone regeneration substitute and, optionally, the covering membrane as defined above.

[0025] According to a preferred embodiment, the device intended to ensure the maintenance of the bone regeneration substitute and, optionally, of the covering membrane on the bone defect comprises 3c) an intermediate pillar, between 3a) the external pillar and 3b) the covering piece.

[0026] According to another preferred embodiment, the system according to the invention further comprises:

[0027] - and for 3) at least one device ensuring the maintenance of the regeneration substitute- bone formation and, possibly, the covering membrane, 3d) at least one screw which has, at its distal end, an external thread, and provided within the 3a) at least one external pillar and, if present, within the 3c) at least one intermediate pillar, an internal cavity allowing the passage of said 3d) at least one screw but not of its head; and

[0028] - within the 1) at least one anchoring foot, a cavity in which is provided a thread which can cooperate with the thread of the d) at least one screw to allow the assembly of said 1) at least one anchoring foot and 3) at least one device ensuring the maintenance of the bone regeneration substitute and, possibly, of the covering membrane by screwing the thread of the 3d) at least one screw into the thread of the internal cavity of the 1) at least one anchoring foot.

[0029] According to yet another preferred embodiment, 3a) the covering piece forms a single piece with 3b) the external pillar and, optionally, 3c) the intermediate pillar.

[0030] According to a complementary preferred embodiment, the system according to the invention further comprises 4) at least one part which is complementary to 3) at least one device intended to ensure the maintenance of the covering membrane on a bone defect, which 3) at least one complementary part makes it easier for the practitioner to grip it when putting it in place.

[0031] A fourth subject matter relates to a method of bone regeneration for a bone defect site in a jaw bone of a patient, which method comprises the steps of:

[0032] 1) placing an anchor foot within the patient's jaw bone at or near proximity to the bone defect;

[0033] 2) filling the bone defect with a bone regeneration substitute;

[0034] 3) possibly positioning, on this bone regeneration substitute, of a covering membrane;

[0035] 4) installation, preferably on this covering membrane, of a device intended to the maintenance of the bone regeneration substitute and, possibly, the covering membrane as defined previously. DESCRIPTION OF FIGURES

[0036] [Fig.l] is a sectional view of the implantation in the jaw bone of a patient of an embodiment of the bone regeneration system according to the invention.

[0037] [Fig.2] is a sectional view of this same embodiment of the bone regeneration system according to the invention.

[0038] [Fig.3], [Fig.4], [Fig.5] and [Fig.6] show schematic views from different angles of an embodiment of a device for maintaining the bone regeneration substitute according to the invention. DETAILED DESCRIPTION OF THE INVENTION

[0039] Bone regeneration substitutes are well known to those skilled in the art and such a substitute may be chosen from those used for filling bone loss in various pathologies. Such a bone regeneration substitute may consist of a synthetic bone substitute material (for example hydroxyapatite granules), but also of bone particles. Examples of bone regeneration substitutes include RE-BONE, BIO-OSS, BIOSORB-DENTAL, CREOS, ADBONE, TEEBONE, SYBONE, etc.

[0040] As regards the anchoring feet, these are also well known to practitioners and typically take the form of a screw capable of being screwed into a complementary housing prepared and shaped in the patient's jawbone. The patient's jawbone is thus tapped so as to obtain a thread which will then allow the anchoring foot to be fixed. The screw of the anchoring foot may be cylindrical or conical in shape.

[0041] The material of this anchoring foot is advantageously compatible with the biological material of the bone so as to facilitate its osteointegration in the jaw (maxillary and mandibular bone). Typically, this anchoring foot can be made of zirconia (ceramic), titanium or even titanium alloy.

[0042] In terms of dimensions, such an anchor foot has:

[0043] - a length of between 0.2 and 1.5 cm, preferably between 0.5 and 0.8 cm; and

[0044] - a section between 3 and 8 mm, preferably between 3 and 6 mm.

[0045] Covering membranes have been used for a long time in Guided Bone Regeneration (GBR) and are, in fact, well known to practitioners. They can be resorbable or non-resorbable in nature.

[0046] The covering membranes conventionally used are non-resorbable and are made from ePTFE (expanded polytetrafluoroethylene) with the possibility of mechanical reinforcement with a metal frame; typically titanium (ePTFE TR for Titanium Reinforced).

[0047] The resorbable membranes can be either synthetic or collagenous.

[0048] Synthetic membranes are typically made of copolymers of polylactic and polyglycolic acid, which is why they are resorbed by hydrolysis. Examples of such synthetic membranes include membranes marketed under the names ATRISORB, VICRYL, RESOLUT TM / RESOLUT XT.

[0049] Collagen membranes were first used in 1996 and are made from cross-linked or non-cross-linked collagen that is of bovine or porcine origin. with or without crosslinked fibers. Examples of such collagen membranes include membranes marketed under the names AVITENE, PAROGUIDE, BIO-GUIDE, PERIOGEN or BIOMEND.

[0050] The dimensions of the at least one covering membrane are such that it must, preferably, make it possible to cover at least the entire bone defect.

[0051] Typically, such a covering membrane has:

[0052] - a length of between 0.5 and 2.5 cm, preferably between 0.5 and 1.5 cm; and

[0053] - a width between 0.5 and 2.5 cm, preferably between 0.5 and 1.5 cm.

[0054] The device intended to ensure the maintenance of the bone regeneration substitute and, possibly, the covering membrane on the bone defect must have sufficient rigidity to ensure its function. Now and preferably, the covering part of this same device must simultaneously have an elasticity which allows its adjustment, during its installation, by the curvature of its elongated lateral extensions, so as to delimit, possibly in combination with the covering membrane, the regeneration volume of the bone defect.

[0055] To do this, the device ensuring the maintenance of the bone regeneration substitute and, possibly, of the covering membrane or, at least, its covering part, is advantageously made of titanium.

[0056] Titanium is a lustrous transition metal with low density and high strength. Pure titanium is thus stronger than ordinary low-carbon steels, while being 45% lighter. The integration of titanium into different alloys allows them to be associated with particularly interesting properties. Thus, titanium alloys are generally used for most applications with small amounts of aluminum and vanadium, generally 6% and 4% respectively, by weight. Titanium can be found in two crystalline forms (alpha and beta) and, titanium alloys, depending on their composition, will orient the titanium towards one or the other of these crystalline forms, thereby modifying the properties of the alloy.Among these alloys, Grade 1 titanium, or T35, and Grade 2 titanium, or T40, constitute specific alloys, the composition of which (in Titanium, Oxygen, Iron, Carbon, Hydrogen and Nitrogen) and characteristics are well known to those skilled in the art.

[0057] Advantageously, the device ensuring the maintenance of the bone regeneration substitute and, possibly, of the covering membrane is made of grade 1 or grade 2 titanium.

[0058] According to a preferred embodiment, the 3) at least one device intended to ensure the maintenance of the A) bone regeneration substitute and, optionally, of the 2) at least one covering membrane on the bone defect comprises, between the 3a) at least one external pillar and the 3b) at least one covering piece, a 3c) at least one intermediate pillar which could be described as a transmucosal part.

[0059] Ideally, the height of this 3c) at least one intermediate pillar is in the range from 0.5 to 5 mm, preferably in the range from 1 to 2 mm.

[0060] Preferably, this 3c) at least one intermediate pillar comprises a constriction in the width direction going towards the jaw bone and may, optionally, also comprise a festoon. This constriction ideally has a conical profile, which conical profile is devoid of any potentially vulnerable angle.

[0061] According to another preferred embodiment, the system according to the invention further comprises:

[0062] - and for 3) at least one device ensuring the maintenance of the replacement of regeneration bone formation and, possibly, the covering membrane, 3d) at least one screw which has, at its distal end, an external thread, and provided within the a) at least one external pillar and, if present, within the 3c) at least one intermediate pillar, an internal cavity allowing the passage of said 3d) at least one screw but not of its head; and

[0063] - within the 1) at least one anchoring foot, a cavity in which is provided a thread which can cooperate with the thread of the 3d) at least one screw to allow the assembly of said 1) at least one anchoring foot and 3) at least one device ensuring the maintenance of the bone regeneration substitute and, possibly, of the covering membrane by screwing the thread of the 3d) at least one screw into the thread of the internal cavity of the 1) at least one anchoring foot.

[0064] In this embodiment, this 3d) at least one screw allows the assembly by trans-screwing of said 1) at least one anchoring foot and 3) at least one device ensuring the maintenance of the bone regeneration substitute and, possibly, of the covering membrane.

[0065] Advantageously, the head of said 3d) at least one screw and the 3a) at least one external pillar or, if present, the 3c) at least one intermediate pillar have centering means. Typically, these centering means are such that the head of said d) at least one screw and the 3a) at least one external pillar or, if present, the 3c) at least one intermediate pillar comprise complementary female and male portions. Preferably, these complementary female and male shapes are frustoconical shapes with a vertical axis. Therefore, in addition to centering, these shapes make it possible to inhibit relative movements and to ensure sealing between the d) at least one screw and the a) at least one external pillar or, if present, the c) at least one intermediate pillar.

[0066] Preferably, the d) at least one screw and the a) at least one external pillar or, if present, the 3c) at least one intermediate pillar have complementary centering means which are included in the length of the 3d) at least one screw and in the internal cavity of 3a) at least one external pillar or, if present, of 3c) at least one intermediate pillar.

[0067] Advantageously, a thread is provided within the internal cavity of the a) at least one external pillar. This thread can cooperate with an external thread present, for example on an extractor, so as to allow the disassembly of the 1) at least one anchoring foot of the 3) at least one device intended to ensure the maintenance of the bone regeneration substitute and, possibly, of the covering membrane on said bone defect.

[0068] Now in connection with 3b) at least one covering piece, this has 3bi) a central part, in the extension of 3a) at least one external pillar or, if present, of 3c) at least one intermediate pillar, which 3bi) central part is advantageously circular and then typically takes the form of a washer.

[0069] This 3b) at least one covering piece further has, 3bii) at least 2 elongate lateral extensions, preferably 3bii) at least 3 extensions, which elongate lateral extensions are advantageously flexible.

[0070] Also, the 3bi) central part of the 3b) at least one covering piece constitutes the base of the 3bii) at least 2 elongate lateral extensions, preferably of the 3bii) at least 3 elongate lateral extensions.

[0071] The elongate lateral extensions have a sufficient length and width to allow their positioning on the bone regeneration substitute and, possibly, the covering membrane and to ensure their maintenance. Typically, the elongate lateral extensions have a length of between 3 and 15 mm, preferably between 3 and 10 mm. Typically still, the elongate lateral extensions have a width of between 1 and 8 mm, preferably between 2 and 5 mm.

[0072] Advantageously, and to facilitate the adaptation to each patient of the device intended to ensure the maintenance of the bone regeneration substitute and, possibly, of the covering membrane, each elongate lateral extension may have one or more predetermined breaking points positioned along its length. In this way, and when the practitioner installs the device, the latter will be able to use one or more of these predetermined breaking points, so as to shorten all or part of these elongate lateral extensions and adapt them to the morphology of the patient. Following this shortening, the practitioner will be able, simply and using the instruments at his disposal, to eliminate the angles of the breaking point(s) used, so as not to risk injuring the patient.

[0073] Advantageously again, and always to facilitate the adaptation to each patient of the device intended to ensure the maintenance of the bone regeneration substitute and, possibly, of the covering membrane, each elongated lateral extension may have one or more primers that facilitate its folding and which are positioned along its length. In this way, and when the practitioner installs the device, he will be able to use one or more of these primers, so as to fold all or part of these elongated lateral extensions and adapt them to the patient's morphology.

[0074] The 3bi) central part of the 3b) at least one covering piece has two distinct halves corresponding to a vestibular half and a palatal half corresponding to the half turned to the vestibular side (i.e. towards the outside of the mouth) and the half turned to the palatal side (i.e. towards the palate) respectively.

[0075] Advantageously, the elongate lateral extensions in the extension of the vestibular half of the central part, or vestibular elongate lateral extensions, have a length greater than the elongate lateral extensions in the extension of the palatal half of the central part or palatal elongate lateral extensions.

[0076] This characteristic makes it easier for the practitioner to differentiate between the vestibular side and the palatal side of the device intended to ensure the maintenance of the bone regeneration substitute and, possibly, the covering membrane.

[0077] Typically, the vestibular longilinear lateral extensions have a length of between 4 and 10 mm.

[0078] Advantageously, there will be 2 to 5 elongate vestibular lateral extensions, preferably 3 to 4 and, particularly preferably, 3 elongate vestibular lateral extensions.

[0079] Ideally, the elongate vestibular lateral extensions have the same spacing between them. Typically, said spacing is at least 10°, preferably at least 20° and, particularly preferably, at least 25°.

[0080] As for the lateral longilinear palatal extensions, their length is typically between 3 and 6 mm.

[0081] Advantageously, there will be 1 to 4 elongate palatal lateral extensions, preferably 2 to 3 and, particularly preferably, 2 elongate palatal lateral extensions.

[0082] Ideally, the lateral palatal elongate extensions have the same spacing between them. Typically, said spacing is at least 10°, preferably at least 20° and, particularly preferably, at least 25°.

[0083] To present its particularly advantageous properties:

[0084] - 3bi) at least one central part of 3b) at least one covering piece 3) at least one device according to the invention has a thickness of between 0.3 and 3 mm, preferably between 0.5 and 1.5 mm.

[0085] - the elongated lateral extensions have a thickness of between 0.1 and 1.5mm, preferably between 0.3 and 1mm.

[0086] According to another preferred embodiment, the 3b) at least one covering piece forms a single piece with the 3a) at least one external pillar and, optionally, the 3c) at least one intermediate pillar. To do this, these can be produced simultaneously in a single piece or be coupled subsequently, in particular by welding or crimping.

[0087] Production methods suitable for manufacturing 3b) at least one covering part with 3a) at least one external pillar and / or with 3c) at least one intermediate pillar in a single part are well known to those skilled in the art. Examples of such methods include molding, milling, or 3D printing. In the case of such 3D printing, this typically uses a metal powder, the shaping of which is ensured by a laser of suitable power.

[0088] Similarly, the welding or crimping can be carried out by techniques well known to those skilled in the art. In the case where 3) at least one device is made of titanium or a titanium alloy, the welding of its various components can then in particular be carried out by laser, by friction or by electron bombardment.

[0089] In connection with the 4) at least one complementary part of the device ensuring the maintenance of the covering membrane (6) and which makes it easier for the practitioner to grip said device, this 4) at least one complementary part therefore makes it easier for the practitioner to position said 3) at least one device on the 1) at least one anchoring pillar in the patient's mouth.

[0090] Typically, this complementary part which constitutes a means of gripping takes the form of a sleeve, which can be made of plastic, and which is clipped to the central part of the 3) at least one covering part (8), typically in a housing provided within this central part.

[0091] The following examples are provided for illustration purposes and do not limit the scope of the present invention.

[0092] Bone regeneration of a jaw bone defect for the purpose of dental implant placement

[0093] In the context of a bone defect within the jaw, it is necessary to allow regeneration of this bone defect before being able to consider the placement of dental implants.

[0094] To do this, an incision in the gum is made to access this bone defect in the jaw. This incision is made by raising the flap of gum following the incision.

[0095] The practitioner can then drill into the jawbone, ideally at or near the bone defect. The practitioner then places an anchor foot in the previously drilled hole.

[0096] Once this pose is carried out, the practitioner fills the bone defect with a bone regeneration substitute.

[0097] [Fig.l] offers a sectional view of the incised gum so as to access the bone defect with the elevation of a flap (L) of gum following the incision. We also observe the anchoring foot (3) positioned within the drilling which was carried out by the practitioner in the bone (1) of the patient's jaw. Around the anchoring foot (3), we can see the filling of the bone defect by the bone regeneration substitute (11). The anchoring foot (3) is overhung by the device (2) for holding the bone regeneration substrate (11) with which it is associated by a screw (9). Note that, in this section, the covering membrane (6) is positioned on the device (2).

[0098] [Fig.2] shows a sectional view this time of the bone regeneration system presented in [Fig.l], in which we observe the anchoring foot (3) and the device (2) with its elongated lateral extensions (7a, 7b). This anchoring foot (3) and this device (2) are associated by screwing the external thread (9a) of a screw (9) into the tapping (3b) of the internal cavity (3a) of the anchoring foot (3). Indeed, an internal cavity (4a) of the device (2) for holding the bone regeneration substitute (11) allows the passage of this screw (9) but not of its head (9b).

[0099] Figures 3 to 6 show schematic views from different angles of a device (2) for holding the bone regeneration substitute. In these, the device (2) can be seen with its external pillar (4), which external pillar (4) is equipped with anti-rotational means in the form of a Morse cone so as to limit the movements of the device (2) once its external pillar (4) is placed in place within the complementary cavity of the anchoring foot (see [Fig.2]). This external pillar (4) is topped by an intermediate pillar (5) of conical shape so as to facilitate its passage within the gum. Above the intermediate pillar (5), the covering piece (8) is positioned with its cylindrical central part (12), which central part (12) is in line with the extension of the intermediate pillar (5).The elongate lateral extensions (7a, 7b) of the covering piece (8) comprise two elongate palatal lateral extensions (7b), the shortest, and three elongate vestibular lateral extensions (7a), the longest. These latter elongate vestibular lateral extensions (7a) each further comprise a breaking point (10) which makes it easier for the practitioner to adjust the device (2) so as to ensure a safe and comfortable fit adapted to the patient. These same elongate vestibular lateral extensions (7a) also comprise two primers (13), positioned along its length, to make it easier for the practitioner to fold these extensions and adjust the device to the patient's morphology.

[0100] [Fig.4] shows an aerial perspective of the covering part (8) of the device (2), which allows a better understanding of the specific arrangement of its components. In this view, we observe the elongated lateral extensions (7a, 7b) in the extension of the central part (12) whose axis intersects perpendicularly the central axis (AA) (visible in [Fig.6] also). We also observe in this view, the internal cavity (4a) passing through the covering part (8), but also (not visible in this view) the external pillar and the intermediate pillar.

Claims

Claims

1. A device (2) for maintaining a bone regeneration substitute and, optionally, a covering membrane (6) on a bone defect of a patient which comprises: 3a) on its face directed towards the bone (1), at least one external pillar (4) intended to be fixed in an anchoring foot (3), which external pillar (4) comprises anti-rotational means for inhibiting relative movements of the external pillar (4) with respect to the anchoring foot (3) once the external pillar (4) is placed in the anchoring foot (3); and 3b) on its face opposite the bone (1), at least one covering piece (8) placed on the bone regeneration substitute (11) and, optionally, the covering membrane (6) so as to delimit, in combination with said bone regeneration substitute (11) and, optionally, said covering membrane (6), the volume of bone regeneration at said bone defect site,which covering part (8) has: 3bi) a central part (12), in the extension of the external pillar (4), and 3bii) at least 2 elongate lateral extensions (7a, 7b) in the extension of this i) central part (12) whose axis intersects perpendicularly the central axis (AA), corresponding to the axis passing through the central part (12) and the 1) at least one anchoring pillar (3), preferably each elongate lateral extension (7a, 7b) does not include any orifice intended for the positioning of a fixing screw and / or said elongate lateral extensions (7a, 7b) are flexible.,

2. The device according to claim 1, characterized in that the elongate lateral extensions (7a, 7b) have a length of between 3 and 15 mm, preferably between 3 and 10 mm.

3. The device according to any one of claims 1 or 2, characterized in that each elongate lateral extension (7a, 7b) has one or more predetermined breaking points (10) positioned along its length.

4. The device according to any one of claims 1 to 3, characterized in that it comprises 3c) an intermediate pillar (5), between 3a) the external pillar (4) and 3b) the covering piece (8).

5. The device according to any one of claims 1 to 4, characterized in that a) the covering piece (8) forms a single and same part with b) the external pillar (4).

6. A system for bone regeneration for a bone defect site in a jaw bone (1) of a patient with a bone regeneration substitute (11) for filling said bone defect which comprises: 1) at least one anchoring foot (3) adapted for installation endosseously in the jaw bone (1), preferably within the bone defect itself; 2) optionally, at least one covering membrane (6), preferably a covering membrane (6) whose surface allows covering at least the entire bone defect; 3) at least one device (2) as defined in any one of claims 1 to 5.

7. The system according to claim 6, characterized in that it comprises 2) at least one covering membrane (6), preferably said at least one covering membrane (6) is of a resorbable or non-resorbable nature.

8. The system according to any one of claims 6 or 7, characterized in that it further comprises 4) at least one part which is complementary to 3) at least one device (2) intended to ensure the maintenance of the bone regeneration substitute (11) and, possibly, of the covering membrane (6) on a bone defect, which 3) at least one complementary part makes it easier for the practitioner to grasp it.

9. The system according to any one of claims 6 to 8 characterized in that it further comprises: - and for 3) at least one device (2) intended to ensure the maintenance of the bone regeneration substitute (11) and, possibly, of the covering membrane (6), 3d) at least one screw (9) which has, at its distal end, an external thread (9a), and arranged within a) at least one external pillar (4) and, if present, within 3c) at least one intermediate pillar (5), an internal cavity (4a) allowing the passage of said 3d) at least one screw (9) but not of its head (9b); and - within the 1) at least one anchoring foot (3), a cavity (3a) in which is provided a thread (3b) which can cooperate with the thread (9a) of the d) at least one screw (9) to allow the assembly of said 1) at least one anchoring foot (3) and 3) at least one device (2) ensuring the maintenance of the bone regeneration substitute (11) and, optionally, of the covering membrane (6) by screwing the thread (9a) of the 3d) at least one screw (9) into the thread (3b) of the internal cavity (3a) of the 1) at least one anchor foot (3).

10. A bone regeneration kit for a bone defect site in a jaw bone (1) of a patient which comprises: A) a bone regeneration substitute (11) allowing the filling of the bone defect and B) a bone regeneration system as defined in any one of claims 6 to 9.

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