Use of Osmanthus fragrans extract for cosmetic treatment

Abstract

The cosmetic treatment according to the invention based on an extract of Osmanthus fragans is suitable for preventing and / or reducing unsightly redness of the skin, in particular caused by exposure to the sun. The treatment is also suitable for jointly preventing skin dryness and increasing cellular dynamism.

Description

Title of the invention: Use of an Osmanthus fragrans extract for a cosmetic treatment

[0001] The present invention relates to the use of an Osmanthus fragrans extract or a composition comprising it for a topical non-therapeutic cosmetic treatment.

[0002] By "cosmetic treatment" is meant a treatment which is intended for healthy skin and / or appendages, said treatment being intended to improve or beautify their appearance and condition. Such a treatment is purely aesthetic, without any therapeutic purpose. The skin and appendages for which the treatment is intended are healthy, normal, i.e. not diseased.

[0003] The present invention relates in particular to the cosmetics industries which manufacture and / or use products intended for the treatment of the skin including the scalp, mucous membranes and appendages (such as hair, eyelashes, eyebrows, nails, hair) of mammals, animals or humans.

[0004] These industries are in increasing demand for new products, in particular in demand for new active ingredients which are derived from plants because these make it possible to combine efficacy, limitation of the risks of irritation and allergy, reduction of side effects, biodegradability, with the possibilities of labeling / certifications and suitability with a logic of sustainable development and / or fair trade.

[0005] At any age, “beautiful” skin will first be expressed by a radiant and even complexion, that is to say with few spots and without unsightly redness.

[0006] Redness of the skin and scalp represents a skin reaction that can have multiple origins.

[0007] The cause may be external, for example contact with a skin care or cleansing product or a hair product (perm or coloring) that is too aggressive, or a mechanical action carried out on the skin such as shaving, exfoliation, hair removal, rubbing with clothing or jewelry. The action of temperature, climate, ultraviolet (UV), infrared (IR), atmospheric pollution, xenobiotics such as unwanted microorganisms and allergens can also cause unsightly redness.

[0008] The cause can also be of internal origin, such as psychological stress, hormonal stress or even linked to perspiration.

[0009] Skin that turns red is often skin that jointly causes sensations of discomfort, heating, tightness and tingling, and which therefore needs to be treated gently to regain not only their homogeneity and shine, but also their comfort.

[0010] The aim of the present invention is to propose a topical non-therapeutic cosmetic treatment which meets this cosmetic need and the need for an active ingredient which is derived from a plant.

[0011] For this purpose, the present invention proposes the use of an extract of Osmanthus fragrans, or of a composition comprising it and a physiologically acceptable medium, for a topical non-therapeutic cosmetic treatment to prevent and / or reduce unsightly redness of the skin.

[0012] Osmanthus fragrans (Scented Osmanthus) is also known as sweet olive. It is an evergreen shrub native to East Asia. It is used in Indian pharmacopoeia and traditional Chinese medicine for its many properties, including antitussive, antioxidant, antirheumatic, antimicrobial, antifungal, and longevity.

[0013] The flowers of Scented Osmanthus are very fragrant and are used like those of jasmines to flavor tea, wine and certain liqueurs. They are also commonly used in Asian cuisine as a condiment or flavoring.

[0014] An extract of Osmanthus fragrans has already been proposed as an anti-glycation agent (patent JP5969738), or capable of promoting the viability of epidermal cells of the skin (patent CN107456411).

[0015] According to the invention, the Osmanthus fragrans extract can be produced from the whole plant or from one or more part(s) of the plant such as the leaf, stem, flower, fruit, seed, root, tuber and / or pericarp. Preferably according to the invention, the Osmanthus fragrans extract according to the invention is produced from the flowers.

[0016] According to the invention, the Osmanthus fragrans extract can be obtained by the usual solid / liquid extraction techniques including for example maceration, simple decoction, infusion, leaching, reflux extraction, subcritical or supercritical fluid extraction, extraction by means of ultrasound or microwaves or any other physical and / or chemical method such as distillation, percolation, digestion, cryoextraction and enzymatic digestion.

[0017] By "maceration" is meant a process consisting of soaking a plant or part of a plant in an extraction solvent at room temperature.

[0018] By "infusion" is meant a process consisting of bringing the extraction solvent to a boil before pouring it onto the plant or part of the plant.

[0019] By "decoction" is meant a process consisting of mixing the plant or part of the plant with the extraction solvent, then bringing the whole to a boil.

[0020] By "digestion" is meant a process consisting of mixing the plant or part of the plant with the extraction solvent, then heating the mixture below the boiling temperature.

[0021] Preferably according to the invention, the Osmanthus fragrans extract is produced using ultrasound or microwaves.

[0022] According to the invention, the extraction is carried out in at least one aqueous, hydroalcoholic, glycolic, lipidic solvent or a mixture thereof, or a polyol chosen from pentane-diol, sorbitol, butylene glycol, pentylene glycol, propylene glycol, hexanol, caprylic / capric triglyceride, a vegetable oil, a vegetable milk such as almond, hazelnut, coconut, oat, spelt, soy, rice, or a mixture thereof or a basic or acidic aqueous solvent for hydrolysis.

[0023] The duration of the extraction by means of ultrasound can vary between 30 minutes and 3 hours, preferably between 1 hour and 2 hours. The temperature is between 10°C and 60°C, preferably at room temperature. The power is between 10 and 40 Watts per kilogram of mixture of plant material and solvent.

[0024] Preferably according to the invention, the extraction solvent is aqueous, consisting of water or a mixture of a glycolic solvent and an aqueous solvent, more preferably a glycerin / water mixture.

[0025] More preferably, according to the invention, the extraction is carried out by means of ultrasound in water or in a glycerin / water mixture.

[0026] According to another aspect of the invention, the extraction by means of microwaves is carried out in at least one solvent chosen from: water, glycerin, hydroalcoholic, propylene glycol, butylene glycol, polyethylene glycol of any molecular weight, monoethyl ether of diethylene glycol, hexylene glycol, but also ethanol, propanol, butanol and other polyols (pentanediol, hexanols, sorbitol and other liquid sugars), vegetable milk, as well as all mixtures of these solvents.

[0027] More preferably, the extraction solvent is a mixture of at least one glycolic solvent and at least one aqueous solvent, more preferably a glycerin / water mixture. The extraction time can vary between 10 and 300 seconds, preferably between 30 and 100 seconds. The power of the microwave generators can vary between 100 and 2000 Watts, the microwave processing frequency being limited between 2000 and 3000 MHz.

[0028] The advantage lies in the fact that the Osmanthus fragrans extract according to the invention thus obtained is highly soluble in water and can therefore be formulated into various formulations for topical application.

[0029] In-vivo tests are given further in the description showing the effectiveness of the treatment with an extract of Osmanthus fragrans according to the invention or of a composition containing it to prevent and / or reduce skin redness. The treatment according to the invention being a purely cosmetic, non-therapeutic treatment, it does not include the treatment of redness which would be due to a burn, in particular due to prolonged exposure to the sun, or redness due to invasive cutaneous action with a wound.

[0030] Thus, the treatment according to the invention is more particularly suitable for treating unsightly redness linked to:

[0031] - exposure to radiation, particularly solar, UVAs, UVBs, IR, light visible such as visible red, blue or green lights which can be used in photobiomodulation also called low energy laser or high energy radiation used in radiotherapy;

[0032] - climatic aggression or linked to exposure to abnormally high temperatures high or low, for example the heat of a bath or wearing a mask which increases skin temperature;

[0033] - friction between two skin parts or with another surface in contact with the skin such as clothing, jewelry, etc.

[0034] - following the creation of a tattoo; skin redness which may be linked to the repeated passage of the needle inserting the pigments into the dermis; and / or

[0035] - an emotional reaction, called a “flush”, linked to stress, anxiety, etc.

[0036] The invention is therefore particularly suitable for the treatment of so-called reactive skin, susceptible to redness following the stimuli mentioned above.

[0037] According to another aspect, the treatment according to the invention is particularly suitable for increasing the production of adenosine triphosphate (ATP). ATP is one of the main sources of energy responsible for cellular dynamism. The reduction of ATP, caused for example by age or exposure to UV rays, can lead to cell death resulting in a slowdown in cell renewal, non-functional cell differentiation causing a reduction in the thickness of the epidermis responsible for a duller, uneven complexion and less good defense against UV-related damage. An increase in the production of ATP can counteract its effects by activating cellular respiration and increasing energy production in the cells. Thus, the cells are more functional and the harmful effects responsible for redness are better absorbed by the skin and appear later.

[0038] Advantageously, the treatment according to the invention is also suitable for treating the sensations of tingling and tightness which often accompany redness. Indeed, as shown by the in vitro tests given below, the Osmanthus fragrans extract according to the invention is also particularly effective for treating dryness of the skin thanks to an increase in the synthesis of acid Hyaluronic acid. Improved skin hydration will restore suppleness to the skin, thereby calming it.

[0039] The cosmetic effects according to the invention, of an aesthetic nature, namely affecting the color of the skin, and of a sensory nature, namely affecting the comfort felt, can be considered separately or in combination. These effects are beneficial for the skin including the scalp.

[0040] The treatment according to the invention can be obtained by using the extract directly or by using a composition comprising it in a physiologically acceptable medium, and optionally other active ingredients.

[0041] By "physiologically acceptable medium" is meant according to the present invention, without being limiting, an aqueous, hydroglycolic or hydroalcoholic solution, a water-in-oil emulsion, an oil-in-water emulsion, a microemulsion, an aqueous gel, an anhydrous gel, a serum, a dispersion of vesicles, a powder.

[0042] “Physiologically acceptable” means that the compositions are suitable for a topical or transdermal use, in contact with the mucous membranes, nails, scalp, hair, fur and skin of mammals and more particularly humans, compositions which can be ingested or injected into the skin, without risk of toxicity, incompatibility, instability, allergic response, and others. This “physiologically acceptable medium” forms what is classically called the excipient of the composition.

[0043] Preferably according to the invention, the physiologically acceptable medium may be an aqueous, hydroglycolic or hydroalcoholic medium, or formed by a water-in-oil emulsion, an oil-in-water emulsion, or a microemulsion. More preferably, it is hydroglycolic. More preferably, the physiologically acceptable medium is a mixture of glycerin and water.

[0044] The present invention thus covers a non-therapeutic topical cosmetic treatment suitable for beautifying or improving the appearance and general condition of the skin and / or the appendages, more particularly for preventing and / or reducing unsightly redness of the skin and / or feelings of tightness and discomfort, comprising the topical application to the skin in a subject in need of an effective amount of the Osmanthus fragrans extract according to the invention or of a composition comprising it in a physiologically acceptable medium.

[0045] The "effective" amount of the Osmanthus fragrans extract according to the invention, that is to say its dosage, depends on the intended use of the composition. It depends on various factors, such as age, the condition of the person or the extent of the disorder. An effective amount means a non-toxic amount sufficient to obtain the desired effect.

[0046] In a composition containing an extract of Osmanthus fragrans according to the invention, to be present in an effective quantity, it is generally found in proportions between 0.000001% and 15% relative to the total weight of the composition, more preferably between 0.00001% and 10%, depending on the intended use of the composition and the desired effect, more or less pronounced. More preferably, the effective amount is between 0.0001% and 5% relative to the total weight of the composition.

[0047] All percentages and ratios used in this application are by weight of the total composition and all measurements are made at 25°C, unless otherwise specified.

[0048] For example, for a cosmetic facial treatment, the European Cosmetics Directive has set a standard application quantity of 2.72 mg / cm2 / day / person for a cream and 0.5 mg / cm2 / day / person for a body lotion.

[0049] According to other particularities, the cosmetic treatment according to the invention can be associated with one or more other treatments targeting the skin, such as light therapy, heat or aromatherapy treatments.

[0050] According to the invention, it is possible to propose multi-compartment devices or kits intended for implementing the method described above, and which could comprise, by way of example, and without this being limiting, in a first compartment a composition containing the Osmanthus fragrans extract according to the invention in an excipient, and in a second compartment an additional active agent acting jointly, the compositions contained in said first and second compartments being considered here as a combination composition for simultaneous, separate or spread out use over time, in particular in one of the treatments defined above.

[0051] According to other advantageous characteristics, the Osmanthus fragrans extract according to the invention can be used in combination with one or more additional active ingredients at effective concentrations advantageously making it possible to offer a synergistic effect or to reinforce activity.

[0052] The additional active ingredients may be chosen, for example, from lightening, anti-redness, anti-blemish, slimming, calming active ingredients for the treatment of sensitive, reactive skin, filtering radiation, in particular UVA, UVB, IR, visible light including blue light, moisturizing, humectant, exfoliating, smoothing, toning, anti-aging, anti-wrinkle and fine lines active ingredients, improving mechanical and elastic properties, radiance of the complexion, detoxifying, anti-hair regrowth active ingredients, acting on the skin barrier, anti-acne, acting on sebum secretion, mattifying, unifying, anti-inflammatory, anti-oxidant, anti-free radical, anti-glycant, eye contour (anti-dark circles and anti-puffiness), promoting blood circulation, peptides, vitamins, etc. These active ingredients may be synthetic or obtained from materials plants, such as plant extracts or products of plant culture, fermentation, bacterial culture or enzymatic culture.

[0053] The "International cosmetic ingredient dictionary & handbook" published by "the Cosmetic, Toiletry, and Fragrance Association, Inc.", Washington, DC describes a wide variety, without limitation, of cosmetic and pharmaceutical ingredients commonly used in the skin care industry, which are suitable for use as additional ingredients in the compositions according to the present invention, as long as they are physically and chemically compatible with the other ingredients of the composition and especially with the actives of the present invention. Furthermore, the nature of these additional ingredients must not unacceptably alter the benefits of the actives of the invention. These additional ingredients may be synthetic or natural such as plant extracts or come from a biotechnological process.

[0054] Other skin care active ingredients which are particularly useful in combination with the composition according to the invention can be found in the commercial documentation of Crodarom, Alban Muller International and Sederma, and on the website www.croda.fr.

[0055] More specifically, the Osmanthus fragrans extract according to the invention can be combined with at least one of the compounds chosen from vitamin compounds, groups BC, E, F, D and A in particular, compounds such as niacinamide or tocopherol, retinoid compounds such as retinol, hyaluronic acid, hexamidine, α-lipoic acid, resveratrol, or DHEA, peptides, ceramides, UV or IR filters, chemical or physical, which are conventional active ingredients used in cosmetic topical compositions.

[0056] The present invention also provides the use of the Osmanthus fragrans extract according to the invention as described above, for the manufacture of a composition for a cosmetic treatment, as described above.

[0057] The composition for use according to the invention can be provided in any galenic form (examples are given further in the description) defined according to the destination of the composition and its site of application.

[0058] A composition according to the invention can be applied to the face, the body, the décolleté, in any form or vehicle known to those skilled in the art, in particular in the form of a solution, dispersion, emulsion, paste or powder, individually or in a premix or be carried individually or in a premix by vectors such as macrocapsules, microcapsules or nanocapsules, macrospheres, microspheres, or nanospheres, liposomes, oleosomes or chylomicrons, macroparticles, microparticles or nanoparticles, macrosponges, microsponges or nanosponges, microemulsions or nanoemulsions, or adsorbed on powdery organic polymers, talcs, bentonites, spores or exines and other mineral or organic supports.

[0059] In cosmetics in particular, applications can be proposed, in particular in the ranges of facial and / or body skin care and makeup-care ranges, in particular eyelashes and eyebrows.

[0060] For example, the galenic form of the composition may be a lotion, a cream, a butter, a milk, a solid form, a mousse, a gel, a deodorant, an antiperspirant, a shampoo, a conditioner, a hair mask, a face mask, a shower gel, etc.

[0061] The galenic formulas can be included in ranges of personal care products and / or beauty products, in particular ranges of skin care, cleansing, makeup, makeup removal, sun care, artificial tanning, pre-shave, shaving, or after-shave, slimming, moisturizing, humectant, emollient, conditioning, exfoliating, astringent, depilatory, antiperspirant or antiperspirant, deodorant, deodorant, perfumes, etc.

[0062] The composition may also be incorporated on a non-woven or woven material, made of natural or synthetic fibers, wool, or on any material intended to come into contact with the skin and which may be used in clothing, in particular tights and socks, shorts, day or night underwear, handkerchiefs, masks, patches or fabrics, in order to exert its cosmetic effect via this skin / textile contact and allow continuous topical delivery (cosmetotextiles).

[0063] According to the invention, there is also provided a woven or non-woven material comprising at least the Osmanthus fragrans extract according to the invention as described above, for use in a non-therapeutic cosmetic treatment. DETAILED DESCRIPTION

[0064] The present invention will be better understood in light of the detailed description of exemplary embodiments and studies described below. 1. Example of obtaining an extract of O smanthus fragrans according to the invention and a composition comprising it.

[0065] Plant material: Osmanthus fragrans flowers.

[0066] Maceration solvent: water or a glycerin / water mixture having a ratio of between 25:75 and 80:20.

[0067] Procedure: Osmanthus fragrans flowers are extracted using ultrasound in the solvent, for 1 hour and 30 minutes, at a power of 22 Watts per kilogram of plant material and solvent. Then, the extract obtained is centrifuged and the supernatant is collected to be filtered. Several successive filtrations are carried out, with a pore size between 27 and 0.1 pm. An extract according to the invention is thus obtained.

[0068] To obtain an active ingredient according to the invention, the extract obtained above is mixed with a physiologically acceptable matrix, consisting of water or a glycerin-water mixture. The glycerin-water ratio in the composition is between 0:100 and 80:20.

[0069] This extract or the active ingredient comprising it can be used in cosmetic compositions, an example of which is given below. 1. Example of cosmetic formulation#

[0070] A cosmetic formulation is described below using the active ingredient according to the invention as described above. Additional active ingredients, where appropriate supporting and / or complementing the activity of the active ingredient comprising the osmanthus fragrans extract according to the invention, may be added in the appropriate phase according to their hydrophobic, hydrophilic or amphiphilic character. These additional active ingredients may be of any category according to their function(s), the place of application (body, face, neck, bust, hands, hair, eyelashes, eyebrows, body hair, etc.), the desired final effect and the targeted consumer, for example anti-aging, anti-wrinkle, moisturizing, anti-dark circles, firming, anti-glycation, slimming, soothing, muscle relaxant, anti-redness, sensitive skin, anti-stretch marks, mattifying, etc.

[0071] The active ingredient according to the invention is recommended at a rate of 1 to 5%, preferably a rate of 2%. It goes without saying that these rates could vary without departing from the scope of the present invention, depending on the more or less pronounced effects sought. Example: Cream shape

[0072] [Tables 1] Raw materials % Name INCI Phase A Water qs. Aqua / water Carbomer 0.3 Carbomer Phase B Brij™ S2-SS-(RB) 0.4 Steareth 2 Brij™ SIO-SO-(RB) 1.2 Steareth 10 Crodafos™ CES-PA-(RB) 4.0 Cetearyl alcohol (and) Dicetyl Phosphate (an d) Ceteth-10 Phosphate Crodacol™ CS90-PA-(RB) 1.5 Cetearyl Alcohol Laurocapram 2.5 Laurocapram Crodamol™ AB-LQ-(RB) 1.5 Cl2-15 Alkyl benzoate Crodamol™ OSU-LQ-(JP) 7.0 Diethylhexyl succinate Phase C Glycerol 2.5 Glycerin Octanediol 0.5 Caprylyl glycol Phase D Phenoxyethanol 0.8 Phenoxyethanol Phase E Potassium sorbate 0.15 Potassium sorbate Phase F Water 4.0 Aqua / Water NaOH 35% 0.37 Sodium hydroxide Phase G Active ingredient according to the invention 2.0 / Operating mode#:

[0073] Swell the carbomer in water (part A), then heat. Weigh and heat B, mix well. Weigh and melt C, mix well and let cool. Weigh D, then add D to C. Add A to C+D while stirring, homogenize. Add B to A+C+D, then add E to A+B+C+D, homogenize. Add F to A+B+C+D+E, homogenize. Add G to A+B+C+D+E+F and homogenize. 1. Evaluation of the different activities of the Osmanthus fragrans extract according to the invention.

[0074] 3.1. Effect on skin dryness - maintenance of hydration Principle

[0075] Hyaluronic acid is a major constituent of the epidermis, participating in the barrier function as well as in maintaining satisfactory hydration of the skin. It is capable of capturing 1000 times its weight in water. It comes in the form of an aqueous and nourishing gel which fills the spaces between the keratinocytes. In this way, it prevents skin dryness, which is known to alter the texture of the skin, giving it a rough and rough feel. Protocol

[0076] Human epidermal keratinocytes were cultured to sub-confluence and then placed in contact with the composition used according to the invention for 3 days. At the end of this contact, the synthesis of hyaluronic acid is evaluated using an ELISA-type assay. An estimation of the quantity of cells by the Hoechst method made it possible to homogenize the results. Results

[0077] Variation in the production of hyaluronic acid by keratinocytes. Effect of the composition according to the invention at 3% compared to the control (n=5):

[0078] [Tables2] Hyaluronic acid (ng / mL / 106 cell.) Variation (%); significance Control 1812+196 Reference 3% of the active ingredient according to the invention 3091 + 441 + 71%; p<0.01

[0079] The results show that the composition according to the invention significantly increases the synthesis of hyaluronic acid in keratinocytes. 3.2. ATP synthesis Protocol

[0080] Human keratinocytes (HaCaT) are cultured to confluence in their culture medium. The cells are then brought into contact with the ingredient according to the invention for 2 hours. Luciferin is converted with ATP into a form capable of being catalytically oxidized (oxyluciferin) by luciferase. The oxyluciferin produced (in an excited state) returns to a stable situation with the emission of a yellow-green light which is measured (X max = 565 nm), the signal obtained is therefore proportional to the quantity of ATP in the cells. Results

[0081] Variation in ATP production by human keratinocytes. Effect of the active ingredient according to the invention at 3% compared to the control (n=5):

[0082] [Tables3] Hyaluronic acid (ng / mL / 106 cell.) Change (%); significance Control 1399 + 162 Reference 2.5% of the active ingredient according to the invention 1966 + 143 + 41%; p<0.01

[0083] The results show that the active ingredient according to the invention significantly increases ATP synthesis. 3.3. Reduction of skin redness Product tested

[0084] The cream described in point 2. above vs. a placebo cream, i.e. with the same chassis as the cream described in point 2. above without the active composition according to the invention. Specific inclusion and exclusion criteria

[0085] The study was carried out on a panel of 19 healthy adult subjects, 9 men and 10 women with an average age of 39 years (between 23 and 58 years).

[0086] The inclusion criteria that had to be met were: - Be a man or a woman, - Be between 18 and 65 years old, and - Have a skin phototype between I and III according to the Fitzpatrick scale and not tanned.

[0087] The exclusion criteria that had to be respected: - Not have any skin disease or any other medical condition interfering with the objectives of the study, - For women, not being pregnant or breastfeeding, and - Not have uneven skin tone, sunburn, scars or lesions in the test area. Type of study, duration, applications

[0088] During the 7 days preceding the test, volunteers were asked not to use any topical preparations on the inner side of the forearms (test area).

[0089] Firstly, the test product is applied to the inner side of the forearms by the volunteers approximately 15 minutes before UV irradiation. A second application is carried out immediately after irradiation and a final application is carried out 24 hours after irradiation.

[0090] For the duration of the study, only water or the provided mild soap was allowed for cleaning. In addition, volunteers were advised to avoid excessive sun exposure and the use of sunbeds was prohibited. Statistics

[0091] For redness values, statistical calculation is performed using a one-sided paired Student's t-test for parametric values. Principle

[0092] The aim of this study is to evaluate the effect of the cream according to the invention on skin redness linked to exposure to UV radiation.

[0093] UV source: 300W Xenon arc lamp solar simulator (Model 601 V2.5 Multisport, Solar Light Co. Inc, USA) equipped with a homogenizer. The entire UVA+UVB spectrum complies with the requirements of ISO 24444:2019. The uniformity of the solar simulator is measured before each test and the spectral output is checked annually.

[0094] An irradiation equivalent to 1.25 MED (light but defined) is performed.

[0095] Measurement conditions: Acclimatization time: 30 min.

[0096] Room temperature: 21 ± 2°C.

[0097] Humidity: 45 ± 10%. Measurement protocol

[0098] Skin colorimetric measurements were carried out on the treated areas on the forearms with a MINOLTA™ CM400 Spectrophotometer before the first application of the test product (D0), 24 hours after irradiation and before the second application (T=24 hours) and 48 hours after irradiation (T=48 hours). Each measurement is an average of six acquisitions on the same skin area. The average value of the measurements was calculated for each subject.

[0099] The spectrophotometer converts the colors perceived by humans into a digital code. The parameter a* allows the study of the spectrum from green to red. A decrease in the parameter a* over time indicates a decrease in skin redness. Results

[0100] The values ​​measured at T0 are subtracted from all results to obtain results relating to the induction of redness while eliminating the initial conditions, i.e. the natural red tint of the skin.

[0101] Variation of redness (parameter a*, arbitrary units) (N=19).

[0102] [Tables4] Cream according to the invention Placebo cream Untreated skin % variation T=48 hours vs. T0 - 38.4% - 33.4% - 28.3% % variation vs. cream according to the invention; significance / - 5.0%; dns* - 10.1%; p<0.06

[0103] * dns = non-significant data

[0104] The results show a statistically significant decrease in redness when the cream according to the invention is used compared to the untreated condition. Redness is not significantly reduced with the use of the placebo cream compared to untreated skin.

Claims

Claims

1. Use of an Osmanthus fragrans extract, or a composition comprising it and a physiologically acceptable medium, for a topical non-therapeutic cosmetic treatment to prevent and / or reduce unsightly redness of healthy skin.

2. Use according to claim 1, for treating redness caused by: - ​​exposure to radiation; - climatic aggression or linked to exposure to abnormally high or low temperatures; and / or - friction between two parts of skin or with another surface in contact with the skin; - an emotional reaction.

3. Use according to claim 2, characterized in that the radiation is due to exposure to the sun.

4. Use according to any one of the preceding claims, for jointly treating skin dryness and reducing discomfort linked to skin tightness.

5. Use according to any one of the preceding claims, characterized in that the extraction solvent is water or a water / glycerin mixture.

6. Use according to any one of the preceding claims, characterized in that the extract is produced from flowers.

7. Use according to any one of the preceding claims, characterized in that the extract is obtained by means of ultrasound or microwaves.

8. Use according to any one of the preceding claims, characterized in that the osmanthus fragrans extract or the composition comprising it is carried by a woven or non-woven material.

9. Woven or non-woven material comprising at least one extract of osmanthus fragrans or a composition comprising it in a physiologically acceptable medium.