CLEANSING AND / OR CARE COMPOSITION FOR KERATINOUS MATERIALS

Abstract

CLEANSING AND / OR CARE COMPOSITION FOR KERATINOUS MATERIALS The present invention relates to a composition, preferably for cleansing and / or caring for keratinous materials, comprising: a) at least one cationic surfactant; b) at least one fatty compound selected from C12-C22 fatty alcohols and C12-C22 fatty acids; c) at least one extract of Tephrosia purpurea seed; and d) niacinamide and / or its derivatives. The present invention also relates to a non-therapeutic process for cleansing and / or caring for keratinous materials comprising applying the composition according to the present invention to the keratinous materials. Figure for the abstract: none

Description

Title of the invention: CLEANSING AND / OR CARE COMPOSITION FOR KERATINOUS MATERIALS technical field

[0001] The present invention relates to a cosmetic composition and its use. In particular, the present invention relates to a composition for cleansing and / or caring for keratinous materials. The present invention also relates to a non-therapeutic process for cleansing and / or caring for keratinous materials. STATE OF THE ART

[0002] Hair loss in young people is a common problem that is usually triggered by stress, unhealthy lifestyle habits, and emotional disturbances. One of the main biochemical markers associated with stress-induced hair loss is cortisol, a hormone that can be triggered by emotional stress. Elevated cortisol levels can lead to systemic and localized increases in the scalp, which in turn can cause follicular inflammation and further damage to hair follicles, ultimately resulting in hair loss.

[0003] Furthermore, the washing and rinsing stage is a critical time for observing hair loss. Strong friction, rubbing, and massaging during washing easily cause significant hair loss at the root and breakage of the fibers. In particular, when consumers comb their hair or run their fingers through it during rinsing, they easily notice many hair fibers remaining on the comb or their fingers.

[0004] Conventional hair and scalp treatments are typically designed to target hair fibers, providing a smooth texture and ease of detangling using cationic polymers. Extensive coating of these fibers by these conditioning polymers easily leads to flat hair and an oily scalp, while also causing irritation and discomfort.

[0005] Some anti-hair loss products are not satisfactory in terms of cleansing and soothing the scalp.

[0006] It is also desirable that the cleaning and / or care products for keratinous materials be stable and can be easily applied.

[0007] Thus, there is still a need for cleaning and / or care products for keratinous materials, which are stable, can be easily applied, can deliver a clean and soothing effect to the scalp and reduce hair loss, while improving the smooth texture and detangling of the hair. Summary of the invention

[0008] An object of the present invention is therefore to develop a cleansing and / or conditioning composition of keratinous materials, which is stable, can be easily applied, can deliver an effective cleansing and soothing effect to the scalp, and reduce hair loss, while improving the smooth texture and detangling of the hair.

[0009] Thus, according to the first aspect, the present invention relates to a composition, preferably for cleaning and / or caring for keratinous materials, comprising: a. at least one cationic surfactant; b. at least one fatty compound selected from C12-C22 fatty alcohols and C12-C22 fatty acids; c. at least one extract of tephrosia purpurea seed; and d. niacinamide and / or its derivatives.

[0010] According to a second aspect, the present invention proposes a non-therapeutic process for cleaning and / or caring for keratinous materials, comprising the application of the composition according to the present invention to the keratinous materials.

[0011] The inventors have discovered that the composition according to the present invention is stable, can be easily applied, delivers an effective cleansing and soothing effect to the scalp and reduces hair loss, while improving the smooth texture and detangling of the hair.

[0012] The inventors also discovered that niacinamide and / or its derivatives can enhance the ability of a tephrosia purpurea seed extract to prevent and / or reduce hair loss.

[0013] According to a third aspect, the present invention proposes the use of niacinamide and / or its derivatives to promote the ability of a tephrosia purpurea seed extract to prevent and / or reduce hair loss.

[0014] Other subjects, features, aspects, and advantages of the present invention will be presented in the following description and will be partly evident from the description or may be learned through practice of the present invention. DETAILED DESCRIPTION OF THE INVENTION

[0015] As used herein, unless otherwise indicated, the limits of a range of values ​​are included in that range, in particular in the expressions "between... and..." and "from... to...".

[0016] As used herein, the term "including" should be interpreted as encompassing all the features specifically mentioned as well as those optional, additional, unspecified.

[0017] As used herein, the use of the term "comprising" also discloses the embodiment in which no features other than the features specifically mentioned are present (i.e., * consisting of").

[0018] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as that commonly accepted by a person skilled in the art of the present invention. Where the definition of a term in this description conflicts with the meaning commonly accepted by a person skilled in the art of the present invention, the definition described herein shall prevail.

[0019] Unless otherwise specified, all numerical values ​​expressing a quantity of ingredients and the like used in the description and claims shall be understood as modified by the term "approximately". Accordingly, unless otherwise stated, the numerical values ​​and parameters described herein are approximate values ​​that may be modified according to the desired performance obtained as required.

[0020] As used herein, the expression "at least one" used in this description is equivalent to the expression "one or more".

[0021] For the purposes of the present invention, the term "keratinous materials" includes keratinous fibers, such as hair, and skin, such as the scalp.

[0022] For the purposes of the present invention, and unless otherwise indicated:

[0023] - an "alkyl" radical means a linear or branched saturated radical containing, by for example, from 1 to 30 carbon atoms;

[0024] - an "alkenyl" radical designates a hydrocarbon group formed when an atom hydrogen is removed from an alkene group.

[0025] According to the first aspect of the present invention, the composition according to the present invention comprises: a. at least one cationic surfactant; b. at least one fatty compound selected from C12-C22 fatty alcohols and C12-C22 fatty acids; c. at least one extract of tephrosia purpurea seed; and d. niacinamide and / or its derivatives. Cationic surfactants

[0026] The composition according to the present invention comprises at least one cationic surfactant.

[0027] Preferably, the cationic surfactant is chosen from fatty amine compounds, for example fatty amidoamines corresponding to the following formula (I) and their salts:

[0028] RCONHR"N(R')2 (I)

[0029] wherein R is an acyclic, linear or branched alkyl or alkenyl group containing 16 to 22 carbon atoms;

[0030] R" is a divalent hydrocarbon radical containing less than 6 carbon atoms; and

[0031] the R's, which may be identical or different, represent a hydrocarbon radical containing less than 6 carbon atoms.

[0032] Preferably, R" represents a divalent hydrocarbon radical containing 2 or 3 carbon atoms.

[0033] Preferably, the R' groups, which may be identical or different, are linear or branched, saturated or unsaturated, substituted or unsubstituted. More preferably, the R' groups are methyl groups.

[0034] Preferably, the cationic surfactant is selected from oleamidopropyl dimethylamine, stearamidopropyl dimethylamine, isostearamidopropyl dimethylamine, stearamidoethyl dimethylamine, behenamidopropyl dimethylamine, palmitamidopropyl dimethylamine, brassicamidopropyl dimethylamine, stearamidoethyl diethylamine, and mixtures thereof.

[0035] More preferably, the cationic surfactant is chosen from stearamidopropyl dimethylamine, brassicamidopropyl dimethylamine, and mixtures thereof.

[0036] Advantageously, the cationic surfactant is present in the composition according to the present invention in an amount ranging from 0.1% by weight to 20% by weight, preferably from 0.3% by weight to 15% by weight, more preferably from 0.5% by weight to 10% by weight, even more preferably from 0.8% by weight to 5% by weight, relative to the total weight of the composition. Fatty compounds

[0037] According to the first aspect of the present invention, the composition comprises at least one fatty compound selected from C12-C22 fatty alcohols and C12-C22 fatty acids.

[0038] The term "fatty compound" means organic compounds that are insoluble in water at room temperature (25 °C) and atmospheric pressure (760 mmHg) (solubility less than 5%, preferably less than 1%, and more preferably less than 0.1%). Furthermore, fatty compounds are generally soluble in organic solvents under the same temperature and pressure conditions, for example, chloroform, ethanol, benzene, and decamethylcyclopentasiloxane.

[0039] The fatty alcohols that can be used in the composition of the invention can be saturated or unsaturated, linear or branched. Examples include cetyl alcohol, stearyl alcohol, cetostearyl alcohol, myristyl alcohol, lauryl alcohol, tridecyl alcohol, pentadecyl alcohol, hexadecyl alcohol, heptadecyl alcohol, arachidyl alcohol, behenyl alcohol, and mixtures thereof.

[0040] The fatty acid that can be used in the composition of the invention can be linear or branched and comprise from 12 to 22 carbon atoms. Examples include stearic acid, isostearic acid, lauric acid, myristic acid, palmitic acid, palmitoleic acid, arachidic acid, behenic acid, lignoceric acid and mixtures thereof.

[0041] Preferably, the fatty compound is chosen from C14-C20 fatty alcohols and C14-C20 fatty acids.

[0042] More preferably, the fatty compound is chosen from among the C14-C18 fatty alcohols.

[0043] In some preferred embodiments, the composition according to the present invention comprises cetearyl alcohol.

[0044] Advantageously, the fatty compound is present in the composition of the present invention in an amount ranging from 0.1% by weight to 20% by weight, preferably from 0.2% by weight to 15% by weight, more preferably from 0.3% by weight to 10% by weight, even more preferably from 0.4% by weight to 5% by weight, relative to the total weight of the composition.

[0045] The inventors discovered that with the addition of the fatty compound and the cationic surfactant, the composition according to the present invention can provide a smooth layer when rinsing.

[0046] Furthermore, it has been found that the addition of fatty compounds and cationic surfactants improves the texture and stability of the composition according to the present invention. Tephrosia purpurea seed extracts

[0047] The composition of the present invention comprises at least one extract of tephrosia purpurea seed.

[0048] Tephrosia purpurea seed extract belongs to the wild indigo extracts. A specific extraction of the seeds of this plant was carried out to obtain a condensate enriched in specific sugars, including stachyose and ciceritol. This proprietary extract has demonstrated its unique biological capabilities to break down cortisol production by skin cells, activate the release of a natural calming neuropeptide that acts on mood, and visibly improve complexion within two weeks.

[0049] The material is commercially available from Givaudan SA under the brand name Neurophroline®.

[0050] Advantageously, the extract of Tephrosia purpurea seed is present in the composition according to the present invention in an amount ranging from 0.0001% by weight to 10% by weight, preferably from 0.0005% by weight to 5% by weight, plus preferably from 0.001% by weight to 3% by weight, relative to the total weight of the composition. Niacinamide and / or its derivatives

[0051] The composition of the present invention comprises niacinamide and / or its derivatives.

[0052] Niacinamide, also known as vitamin B3, is a compound of formula (II) next:

[0053] Niacinamide derivatives that may be cited include, for example, nicotinic acid, nicotinyl alcohol, nicotinuric acid, nicotinyl hydroxamic acid, nicotinic acid esters such as tocopherol nicotinate, amides derived from niacinamide by substitution of the hydrogen of -CONH2, products from a reaction with carboxylic acids and amino acids, esters of nicotinyl alcohol and carboxylic acids such as acetic acid, salicylic acid, glycolic acid or palmitic acid.

[0054] The following niacinamide derivatives may also be mentioned: 2-chloronicotinamide, 6-methylnicotinamide, 6-aminonicotinamide, N-methylnicotinamide, N,N-dimethylnicotinamide, N-(hydroxymethyl)nicotinamide, quinoline acid imide, nicotinanilide, N-benzylnicotinamide, N-ethylnicotinamide, nifenazone, nicotinaldehyde, isonicotinic acid, methylisonicotinic acid, thionicotinamide, nialamide, 2-mercaptonicotinic acid, nicomol and niaprazine, methyl nicotinate and sodium nicotinate.

[0055] Advantageously, niacinamide and / or its derivatives are present in the composition of the present invention in an amount ranging from 0.001% by weight to 20% by weight, preferably from 0.002% by weight to 15% by weight, more preferably from 0.005% to 10% by weight, even more preferably from 0.005% to 8% by weight, relative to the total weight of the composition. Water

[0056] The composition of the present invention may further include water.

[0057] Advantageously, water is present in the composition of the present invention in an amount ranging from 50% by weight to 99% by weight, preferably from 60% by weight to 98% by weight, relative to the total weight of the composition. Active cosmetic ingredients

[0058] The composition of the present invention may further include one or more additional active ingredients for cleaning and / or caring for keratinous materials.

[0059] In one embodiment of the present invention, the composition of the present invention comprises an active revitalizing agent that provides a sensation of refreshment and / or coolness, such as menthol and its derivatives including ethyl menthane carboxamide, mentyl lactate and menthoxypropanediol.

[0060] A person skilled in the art can select the quantity of additional active ingredients according to the desired objective. Adjuvants

[0061] The composition according to the present invention may also include additional adjuvants, such as perfumes, preservatives, etc.

[0062] A person skilled in the art can choose the quantity of additional adjuvants so as not to have a negative impact on the final use of the composition according to the present invention.

[0063] According to a preferred embodiment, the present invention proposes a composition comprising, relative to the total weight of the composition: a. from 0.8% by weight to 5% by weight of at least one cationic surfactant selected from stearamidopropyl dimethylamine, brassicamidopropyl dimethylamine, and mixtures thereof; b. from 0.4% by weight to 5% by weight of at least one fatty compound chosen from among the C14-C18 fatty alcohols; c. from 0.001% by weight to 3% by weight of Tephrosia purpurea seed extract; and d. from 0.005% by weight to 8% by weight of niacinamide. Preparation and use

[0064] The composition according to the present invention can be prepared by mixing ingredients a), b), c) and d), as essential ingredients, as well as one or more additional ingredient(s), as explained above.

[0065] The method and means for mixing the above ingredients are not limited. Any conventional method and means can be used to mix the above ingredients to prepare the composition according to the present invention.

[0066] The composition of the present invention can be used as a leave-in conditioner or rinse-out conditioner or shampoo for keratinous materials.

[0067] As used herein, the expression "no-rinse conditioner" refers to a conditioner which is applied to keratinous materials and is not subjected to immediate rinsing and / or washing, for example for at least 4 hours.

[0068] As used herein, the expression "rinse-off conditioner" refers to a conditioner which is applied to keratinous materials and is subjected to rinsing and / or washing within a short period of time, for several minutes.

[0069] The composition of the present invention is suitable for application to both the scalp and the hair, preferably with a scalp massage during use to induce a soothing effect.

[0070] According to the second aspect, the present invention proposes a non-therapeutic process for cleaning and / or caring for keratinous materials, comprising the application of the composition according to the present invention to the keratinous materials.

[0071] According to the third aspect, the present invention proposes a use of niacinamide and / or its derivatives to promote the ability of a tephrosia purpurea seed extract to prevent and / or reduce hair loss. EXAMPLES

[0072] The examples provided herein are provided by way of illustration to demonstrate the present invention and are not intended to limit its scope.

[0073] The main raw materials used, their trade names and their suppliers are listed in Table 1.

[0074] [Tables 1] INCI Name Trade Name Supplier Tephrosia purpurea seed extract (Tephrosia purpurea seed extract) NEUROPHROLINE GIVAUDAN Niacinamide NIACINAMIDE PC DSM NUTRITI ONAL PRODU CTS Stearamidopropyl dimethylamine (Stearamidopropyl dimethylamine) TEGO AMID S 18 MB EVONIK Cetearyl alcohol (Cetearyl alcohol) LANETTE O BASF

[0075] Inventive Examples 1-2 and Comparative Examples 1-4

[0076] The compositions of Inventive Examples (El) 1-2 and Comparative Examples (EC.) 1-4 were prepared according to the quantities of ingredients given in Table 2. The quantity of each ingredient is given as a % by weight relative to the total weight of the composition, unless otherwise indicated. Table #2

[0077] Ingredients El. 1 El. 2 EC. 1 EC. 2 EC. 3 EC. 4 Stearamidopropyl dimethylamine 2 1 2 2 2 - Cetearyl alcohol 1 1 1 1 - 1 Tephrosia purpurea seed extract 0.05 0.02 - 0.05 0.05 0.05 Niacinamide 2 2 2 - 2 2 Water QSP1 00 QSP1 00 QSP1 00 QSP1 00 QSP1 00 *QSP100 denotes a quantity sufficient to fill to 100%. The compositions in inventive examples 1-2 represent compositions of the

[0078]

[0079]

[0080]

[0081]

[0082]

[0083]

[0084]

[0085]

[0086] present invention. The composition of comparative example 1 does not include at least one extract of tephrosia purpurea. The composition of comparative example 2 does not include niacinamide and / or its derivatives. The composition of comparative example 3 does not include at least one fatty compound selected from C12-C22 fatty alcohols and C12-C22 fatty acids. The composition of comparative example 4 does not include at least one cationic surfactant. Preparation procedure: The above compositions were prepared according to the following steps: 1. Adding water into a main container; 2. premixing of stearamidopropyl dimethylamine with cetearyl alcohol at 65 °C with stirring for 5 minutes to obtain a uniform mixture, then adding the mixture (for inventive examples 1 and 2 and comparative examples 1 and 2), or of stearamidopropyl dimethylamine (for comparative example 3), or of cetearyl alcohol (for comparative example 4) into the main container, then cooling the resulting mixture to room temperature; 3. Adding tephrosia purpurea seed extract (if applicable) and niacinamide (if applicable) to the main container with stirring to obtain the compositions. It was observed that the composition of comparative example 4 cannot be prepared as a uniform system due to phase separation. Evaluation

[0087] The compositions of inventive examples 1 and 2 and comparative examples 1 to 3 were evaluated for their stability, texture and application performance, hair care performance and the beneficial effect thus provided to the scalp. The composition of comparative example 4 was not evaluated because a uniform system cannot be formed. Texture and application performance

[0088] The texture and application performance of each composition of inventive examples 1 and 2 and comparative examples 1 to 3 were evaluated by applying and spreading each composition on the back of a specialist's hand for texture and application performance evaluation.

[0089] The results on texture and application performance have been summarized in Table 3.

[0090] [Tables3] Properties El. 1 EI.2 EC. 1 EC. 2 EC. 3 Texture Light texture Thick texture Too thin Application performance Easy to spread Not easy to spread Runs easily

[0091] It can be seen in Table 3 that the compositions of inventive examples 1 and 2 and of comparative example 1 have a light texture and can be easily spread, while the composition of comparative example 2 is too thick and cannot be easily spread, and the composition of comparative example 3 is too thin and flows easily. Stability

[0092] Each composition of inventive examples 1 and 2 and comparative examples 1 to 3 was introduced into four 100 mL glass bottles and stored at 4 °C, at room temperature (25 °C) and at 45 °C for 2 months respectively, and at 50 °C for 2 weeks, then the change in appearance of each composition was checked.

[0093] If no phase separation, crystallization, color change, or flocculation is observed in the test composition after the test period, this means that the composition passes the test. Otherwise, the test composition fails the test.

[0094] The results of the stability of the compositions of inventive examples 1 and 2 and of comparative examples 1 to 3 have been summarized in Table 4.

[0095] [Tables4] Properties El. 1 EI.2 EC. 1 EC. 2 EC. 3 Stability Success Success Failure after storage at 45°C for 2 months

[0096] It can be seen in Table 4 that the compositions of inventive examples 1 and 2 and comparative examples 1 and 2 can pass the stability test, the composition of comparative example 3 cannot pass the stability test after being stored at 45 °C for 2 months. Smooth texture and detangling

[0097] The smooth texture and detangling of the hair during rinsing provided by each composition of inventive examples 1 and 2 and comparative examples 2 and 3 were evaluated as follows: 1. Twenty highly trained sensory experts were invited to participate in the trial. These experts were thoroughly trained in the sensory evaluation of shampoos, having tested over 50 different types with varying performance levels. They were able to rate the performance of each sensory control point (such as smoothness, detangling, etc.) on a scale of 0 to 10, where 0 represents the lowest performance for that control point and 10 represents the highest performance. 2. Instruction given to the experts to use each composition of inventive examples 1 and 2 and comparative examples 2 and 3 by following the steps below:

[0098] - application of 12 g of the composition to the entire head of hair and scalp hairy;

[0099] - massage for 2 minutes;

[0100] - rinsing of the composition;

[0101] - blowing on the hair to dry it completely; 1. Then, the smooth texture and detangling of the hair provided by each composition were rated by sensory experts according to the training standard, and the scores were averaged for each composition.

[0102] The results on the smooth texture and detangling of the hair provided by the compositions of inventive examples 1 and 2 and comparative examples 2 and 3 are summarized in Table 5.

[0103] [Table 5]

[0104] [Tables5] Properties El. 1 EI.2 EC. 2 EC. 3 Smooth hair texture 8 7 4 3 Hair detangling 8 7 3 2

[0105] It can be seen in Table 5 that each composition of inventive examples 1 and 2 can give the hair a good smooth texture and good detangling.

[0106] Resistance to hair loss, soothing of the scalp and cleansing of the scalp

[0107] Each composition of inventive examples 1 and 2 and comparative examples 1 to 3 was evaluated in terms of resistance to hair loss, scalp soothing and scalp cleansing according to the following consumer test protocols: 1. Recruitment of 30 young women (subjects), aged 22 to 35, who had themselves reported a hair loss problem; 2. division of the young women into 5 groups (6 subjects / group); 3. Instructions given to subjects to use each composition of inventive examples 1 and 2 and comparative examples 1 to 3 every day at home for two weeks, wherein the instruction for use is the following protocol:

[0108] - application of 12 g of the composition to the entire head of hair and scalp hairy;

[0109] - massage for 2 minutes;

[0110] - rinsing of the composition;

[0111] - blowing on the hair to dry it completely; 1. After a 2-week usage period, feedback from subjects was collected via a questionnaire based on their user experience during the trial period, with the following questions:

[0112] - I experience less hair loss during hair washing than before;

[0113] - My scalp is more soothed than before;

[0114] - My scalp is cleaner after washing than before.

[0115] The answers to the questions were given according to the following scoring standard, and the scores for each composition were averaged.

[0116] 5 means very likely.

[0117] 4 means probable.

[0118] 3 means no difference.

[0119] 2 means improbable.

[0120] 1 means very unlikely.

[0121] The results on resistance to hair loss, scalp cleansing and scalp soothing of the compositions of inventive examples 1 and 2 and comparative examples 1 to 3 have been summarized in Table 6.

[0122] [Table 6]

[0123] [Tableauxô] Properties El. 1 EI.2 EC. 1 EC. 2 EC. 3 Hair loss resistance 4.8 4.5 3.5 3 2.8 Scalp soothing 4.8 4.8 2.5 2.2 3.5 Scalp cleansing 4.5 4.5 4 3.8 4

[0124] It can be seen in Table 6 that the compositions of inventive examples 1 and 2 demonstrate good resistance to hair loss, and can deliver the cleansing and soothing effect to the scalp.

Claims

Demands

1. Composition, preferably for cleansing and / or conditioning keratinous materials, comprising: a) at least one cationic surfactant; b) at least one fatty compound selected from C12-C22 fatty alcohols and C12-C22 fatty acids; c) at least one extract of Tephrosia purpurea seed; and d) niacinamide and / or its derivatives.

2. Composition according to claim 1, wherein the cationic surfactant is selected from the fatty amidoamines corresponding to the following formula (I) and their salts: RCONHR"N(R')2 (I) in which R is an acyclic, linear or branched alkyl or alkenyl group containing from 16 to 22 carbon atoms; R" is a divalent hydrocarbon radical containing less than 6 carbon atoms; and the R's, which may be identical or different, represent a hydrocarbon radical containing less than 6 carbon atoms, preferably, the cationic surfactant is selected from oleamidopropyl dimethylamine, stearamidopropyl dimethylamine, isostearamidopropyl dimethylamine, stearamidoethyl dimethylamine, behenamidopropyl dimethylamine, palmitamidopropyl dimethylamine, brassicamidopropyl dimethylamine, stearamidoethyl diethylamine, and mixtures thereof.

3. Composition according to any one of claims 1 and 2, wherein the fatty compound is selected from C14-C20 fatty alcohols, C14-C20 fatty acids and mixtures thereof, preferably selected from C14-C18 fatty alcohols.

4. Composition according to claims 1 to 3, wherein tephrosia purpurea seed extract is present in an amount from 0.0001% by weight to 10% by weight, preferably from 0.0005% by weight to 5% by weight, more preferably from 0.001% by weight to 3% by weight, relative to the total weight of the composition.

5. Composition according to any one of claims 1 to 4, wherein the niacinamide derivative is selected from 2-chloronicotinamide, 6-methylnicotinamide, 6-aminonicotinamide, N-methylnicotinamide, N,N- dimethylnicotinamide, N-(hydroxymethyl)nicotinamide, quinolinenic acid imide, nicotinanilide, N-benzylnicotinamide, N-ethylnicotinamide, nifenazone, nicotinaldehyde, isonicotinic acid, methylisonicotinic acid, thionicotinamide, nialamide, 2-mercaptonicotinic acid, nicomol, niaprazine, methyl nicotinate, sodium nicotinate, and mixtures thereof.

6. Composition according to any one of claims 1 to 5, further comprising water.

7. Composition according to claim 1, comprising, in relation to the total weight of the composition: a) 0.8% by weight to 5% by weight of at least one cationic surfactant selected from stearamidopropyl dimethylamine, brassicamidopropyl dimethylamine, and mixtures thereof; b) 0.4% by weight to 5% by weight of at least one fatty compound selected from C14-C18 fatty alcohols; c) 0.001% by weight to 3% by weight of tephrosia purpurea seed extract; d) 0.005% by weight to 8% by weight of niacinamide.

8. Non-therapeutic process for cleaning and / or caring for keratinous materials, comprising the application of the composition according to any one of claims 1 to 7 on keratinous materials.

9. Use of a compound selected from niacinamide and its derivatives to enhance the ability of a tephrosia purpurea seed extract to prevent and / or reduce hair loss.

10. Use according to claim 9, wherein the niacinamide derivative is selected from 2-chloronicotinamide, 6-methylnicotinamide, 6-aminonicotinamide, N-methylnicotinamide, N,N-dimethylnicotinamide, N-(hydroxymethyl)nicotinamide, quinolinenic acid imide, nicotinanilide, N-benzylnicotinamide, N-ethylnicotinamide, nifenazone, nicotinaldehyde, isonicotinic acid, methylisonicotinic acid, thionicotinamide, nialamide, 2-mercaptonicotinic acid, nicomol, niaprazine, methyl nicotinate, sodium nicotinate, and mixtures thereof.