Cell encapsulation system incorporating solution dispensers

The cell encapsulation system addresses flow rate and bubble issues in existing systems by using upward-flowing distributors and controlled displacement systems to form homogeneous microcompartments, enhancing production quality and cell culture efficiency.

FR3170504A1Pending Publication Date: 2026-06-26TREEFROG THERAPEUTICS

Patent Information

Authority / Receiving Office
FR · FR
Patent Type
Applications
Current Assignee / Owner
TREEFROG THERAPEUTICS
Filing Date
2024-12-23
Publication Date
2026-06-26

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Abstract

The invention relates to a cell encapsulation system (1), the system comprising at least: a first container (11) for holding a cell solution and a second container (12) for holding a gelling solution, a milli-fluidic or micro-fluidic encapsulation device (20) connected to the containers to form cell microcompartments, the outer layer of which is the gelling solution and the core the cell solution, wherein each container is connected to an inlet of the encapsulation device by a distributor (31, 32) associated with a solution displacement system (41, 42) capable of causing the solution contained in said container (11, 12) to flow from said distributor to the inlet of the encapsulation device (20), characterized in that the first distributor (31) has at least one upward-extending portion. Figure to be published with the abstract: Fig. 1
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