Autoinjector

Abstract

An autoinjector (10, fig.1a) includes a housing (12, fig.1a), a pre-filled syringe (16, fig.1a) fixed relative to the housing, a drive chassis (24, fig.3) being biased, fixed and moveable with respect

Claims

1. An autoinjector (10) comprising:a housing (12),a pre-filled syringe (16) mounted in the housing (12) and fixed relative to the housing (12), anda needle guard (18) mounted axially moveable in the housing (12) for movement between a storage state, a dispensing state and a lock-out state in which states the needle guard (18) adopts different axial positions relative to the housing (12), the needle guard (18) comprising one or more clip arms (184), with the one or more clip arms (184) being configured to engage a corresponding cut-out (174, 174’) in the housing (12) of the autoinjector (10) in the storage state, a drive chassis (24) biased with respect to said housing (12), the drive chassis (24) further being fixed with respect to the housing (12) and a movement relative to the housing (12) in a storage state of the autoinjector (10), the drive chassis (24) being configured to axially move and act on said pre-filled syringe (16) during dispensing, the drive chassis (24) comprising one or more trigger arms (36)wherein a respective one of the one or more trigger arms (36) is configured to engage a respective one of one or more clip arms (174, 174’) of the needle guard (18) on moving the needle guard (18) in the proximal direction between the dispensing state and the lock-out state, wherein the drive chassis (24) is configured to prevent the one or more clip arms (184) from engaging the housing (12) during release of the needle guard (18) on transitioning from the dispensing state into the lock-out state of the autoinjector (10).

2. The autoinjector (10) according to claim 1,further comprising a lock-out spring (76) arranged between the needle guard (18) and the housing (12), optionallywherein the needle guard (18) is configured to compress the lock-out spring (76) on moving between the storage state and the dispensing state, and wherein the needle guard (18) is configured to be moved by a relaxation of the lock-out spring (76) between the dispensing state and the locked out state.

3. The autoinjector (10) according to one of claims 1 to 2,wherein an axial movement of the needle guard (18) towards the drive chassis (24) releases the fixing of the drive chassis (24) with respect to the housing (12) on activation of the autoinjector (10).

4. The autoinjector (10) according to one of claims 1 to 3,wherein a release mechanism (40) comprises the one or more trigger arms (36) arranged at the drive chassis (24), the one or more trigger arms (36) cooperating with a respective stop feature (54) arranged at the housing (12), with a plunger arm (142) being configured to deflect the one or more trigger arms (36) on a distal axial movement of the needle guard (18).

5. The autoinjector (10) according to one of claims 1 to 4,wherein the one or more clip arms (184) each comprise a block at an end thereof, with the block being configured to engage a lock-out surface of the cut-out (174, 174’) in the housing (12) of the autoinjector (10) in the lock-out state.

6. The autoinjector (10) according to one of claims 1 to 5, wherein the cut-out (174, 174’) is at least generally L-shaped respectively is L-shaped, with the lock-out surface being arranged at a short limb of the L-shaped cut-out (174,174’).

7. The autoinjector (10) according to claim 6, wherein the lock-out surface is arranged at an angle to a long limb of the L-shaped cut-out (174, 174’).

8. The autoinjector (10) according to claim 6 and claim 7, wherein the short limb and the long limb of the L-shaped cut-out (174, 174’) are arranged at an angle to one another, with the angle being selected in the range of 10 to 120°; in particular of 20 to 80°.

9. The autoinjector (10) according to one of claims 1 to 8, wherein the one or more clip arms (184) extend in a proximal direction from the needle guard (18).

10. The autoinjector according to one of claims 1 to 9, wherein the one or more clip arms (184) extend in a proximal direction from the plunger arm (142) of the needle guard (18).

11. The autoinjector according to one of claims 1 to 10, wherein the needle guard (18) comprises a plunger arm (142) for activation of a release mechanism (40) of the autoinjector (10), and wherein the release mechanism (40) is arranged between the housing (12) and the drive chassis (24) of the autoinjector.

12. The autoinjector according to one of claims 1 to 11, wherein the needle guard (18) comprises a sleeve (230) at a proximal end (92) thereof.

13. The autoinjector according to claim 12, wherein the needle guard (18) is of at least generally T-shaped design respectively is of T-shape, with the plunger arm (142) being arranged in parallel to an axial direction (A) of the autoinjector (10) from a proximal end (92) to a distal end of said sleeve (230).

14. The autoinjector according to claim 12 or claim 13, wherein the sleeve (230) comprises one or more elongate slots (232) extending in parallel to an axial direction (A) of the autoinjector (10) from a proximal end (92) to a distal end of said sleeve (230).

15. The autoinjector according to one of claims 1 to 14, wherein the housing (12) comprises an inner body (80) and an outer body (82), with the cut-out (174, 174’) being arranged at the inner body (180).

16. An autoinjector (10) comprising:a housing (12),a pre-filled syringe (16) mounted in the housing (12) and fixed relative to the housing (12), and a needle guard (18) mounted axially moveable in the housing (12) for movement between a storage state, a dispensing state and a lock-out state in which states the needle guard (18) adopts different axial positions relative to the housing (12), the needle guard (18) comprising one or more clip arms (184), with the one or more clip arms (184) being configured to engage a corresponding cut-out (174, 174’) in the housing (12) of the autoinjector (10) in the storage state, a drive chassis (24) biased with respect to said housing (12), the drive chassis (24) further being fixed with respect to the housing (12) and a movement relative to the housing (12) in a storage state of the autoinjector (10), the drive chassis (24) being configured to axially move and act on said pre-filled syringe (16) during dispensing, wherein the needle guard (18) is configured to be axially moved in a distal direction between the storage state and the dispensing state andwherein the needle guard (18) is configured to be axially moved in a proximal direction between the dispensing state and the lock-out state,wherein the needle guard (18) comprises a plunger arm (142) for activation of a release mechanism (40) of the autoinjector (10), andwherein the release mechanism (40) is arranged between the housing (12) and the drive chassis (24) of the autoinjector.

17. The autoinjector (10) according to claim 16,further comprising a lock-out spring (76) arranged between the needle guard (18) and the housing (12), optionallywherein the needle guard (18) is configured to compress the lock-out spring (76) on moving between the storage state and the dispensing state, and wherein the needle guard (18) is configured to be moved by a relaxation of the lock-out spring (76) between the dispensing state and the locked out state.

18. The autoinjector (10) according to one of claims 1 to 17, wherein an axial movement of the needle guard (18) towards the drive chassis (24) releases the fixing of the drive chassis (24) with respect to the housing (12) on activation of the autoinjector (10).

19. The autoinjector (10) according to one of claims 1 to 18, wherein the release mechanism (40) comprises one or more trigger arms (36) arranged at the drive chassis (24), the one or more trigger arms (36) cooperating with a respective stop feature (54) arranged at the housing (12), with the plunger arm (142) being configured to deflect the one or more trigger arms (36) on a distal axial movement of the needle guard (18).

20. The autoinjector (10) according to one of claims 1 to 19, wherein the one or more clip arms (184) each comprise a block at an end thereof, with the block being configured to engage a lock-out surface of the cut-out (174, 174’) in the housing (12) of the autoinjector (10) in the lock-out state.

21. The autoinjector (10) according to one of claims 1 to 20, wherein the cut-out (174, 174’) is at least generally L-shaped respectively is L-shaped, with the lock-out surface being arranged at a short limb of the L-shaped cut-out (174, 174’).

22. The autoinjector (10) according to claim 21, wherein the lock-out surface is arranged at an angle to a long limb of the L-shaped cut-out (174, 174’).

23. The autoinjector (10) according to claim 21 and claim 22, wherein the short limb and the long limb of the L-shaped cut-out (174, 174’) are arranged at an angle to one another, with the angle being selected in the range of 10 to 120°; in particular of 20 to 80°.

24. The autoinjector (10) according to one of claims 1 to 23, wherein the one or more clip arms (184) extend in a proximal direction from the needle guard (18).

25. The autoinjector according to one of claims 1 to 24, wherein the one or more clip arms (184) extend in a proximal direction from the plunger arm (142) of the needle guard (18).

26. The autoinjector according to one of claims 18 to 25, wherein a respective one of the one or more trigger arms (36) is configured to engage a respective one of the one or more clip arms (174, 174’) on moving the needle guard (18) in the proximal direction between the dispensing state and the lock-out state.

27. The autoinjector according to one of claims 1 to 26, wherein the needle guard (18) comprises a sleeve (230) at a proximal end (92) thereof.

28. The autoinjector according to claim 27, wherein the needle guard (18) is of at least generally T-shaped design respectively is of T-shape, with the plunger arm (142) being arranged in parallel to an axial direction (A) of the autoinjector (10) from a proximal end (92) to a distal end of said sleeve (230).

29. The autoinjector according to claim 27 or claim 28, wherein the sleeve (230) comprises one or more elongate slots (232) extending in parallel to an axial direction (A) of the autoinjector (10) from a proximal end (92) to a distal end of said sleeve (230).

30. An autoinjector (10) comprising:a housing (12),a pre-filled syringe (16) mounted in the housing (12) and fixed relative to the housing (12), and a needle guard (18) mounted axially moveable in the housing (12) for movement between a storage state, a dispensing state and a lock-out state in which states the needle guard (18) adopts different axial positions relative to the housing (12), the needle guard (18) comprising one or more clip arms (184), with the one or more clip arms (184) being configured to engage a corresponding cut-out (174, 174’) in the housing (12) of the autoinjector (10) in the storage state, a drive chassis (24) biased with respect to said housing (12), the drive chassis (24) further being fixed with respect to the housing (12) and a movement relative to the housing (12) in a storage state of the autoinjector (10), the drive chassis (24) being configured to axially move and act on said pre-filled syringe (16) during dispensing, wherein the needle guard (18) is configured to be axially moved in a distal direction between the storage state and the dispensing state andwherein the needle guard (18) is configured to be axially moved in a proximal direction between the dispensing state and the lock-out state,wherein the needle guard (18) comprises a plunger arm (142) for activation of a release mechanism (40) of the autoinjector (10), andwherein the release mechanism (40) is arranged between the housing (12) and the drive chassis (24) of the autoinjector.

31. The autoinjector (10) according to claim 30,further comprising a lock-out spring (76) arranged between the needle guard (18) and the housing (12), optionallywherein the needle guard (18) is configured to compress the lock-out spring (76) on moving between the storage state and the dispensing state, and wherein the needle guard (18) is configured to be moved by a relaxation of the lock-out spring (76) between the dispensing state and the locked out state.

32. The autoinjector (10) according to one of claims 30 to 31, wherein an axial movement of the needle guard (18) towards the drive chassis (24) releases the fixing of the drive chassis (24) with respect to the housing (12) on activation of the autoinjector (10).

33. The autoinjector (10) according to one of claims 30 to 32, wherein the release mechanism (40) comprises one or more trigger arms (36) arranged at the drive chassis (24), the one or more trigger arms (36) cooperating with a respective stop feature (54) arranged at the housing (12), with the plunger arm (142) being configured to deflect the one or more trigger arms (36) on a distal axial movement of the needle guard (18).

34. The autoinjector (10) according to one of claims 30 to 33,wherein the one or more clip arms (184) each comprise a block at an end thereof, with the block being configured to engage a lock-out surface of the cut-out (174, 174’) in the housing (12) of the autoinjector (10) in the lock-out state.

35. The autoinjector (10) according to one of claims 30 to 34, wherein the cut-out (174, 174’) is at least generally L-shaped respectively is L-shaped, with the lock-out surface being arranged at a short limb of the L-shaped cut-out (174, 174’).

36. The autoinjector (10) according to claim 35, wherein the lock-out surface is arranged at an angle to a long limb of the L-shaped cut-out (174, 174’).

37. The autoinjector (10) according to claim 35 and claim 36, wherein the short limb and the long limb of the L-shaped cut-out (174, 174’) are arranged at an angle to one another, with the angle being selected in the range of 10 to 120°; in particular of 20 to 80°.

38. The autoinjector (10) according to one of claims 1 to 37, wherein the one or more clip arms (184) extend in a proximal direction from the needle guard (18).

39. The autoinjector according to one of claims 1 to 38, wherein the one or more clip arms (184) extend in a proximal direction from the plunger arm (142) of the needle guard (18).

40. The autoinjector according to one of claims 33 to 39, wherein a respective one of the one or more trigger arms (36) is configured to engage a respective one of the one or more clip arms (174, 174’) on moving the needle guard (18) in the proximal direction between the dispensing state and the lock-out state.

41. The autoinjector according to one of claims 1 to 40, wherein the needle guard (18) comprises a sleeve (230) at a proximal end (92) thereof.

42. The autoinjector according to claim 41, wherein the needle guard (18) is of at least generally T-shaped design respectively is of T-shape, with the plunger arm (142) being arranged in parallel to an axial direction (A) of the autoinjector (10) from a proximal end (92) to a distal end of said sleeve (230).

43. The autoinjector according to claim 41 or claim 42, wherein the sleeve (230) comprises one or more elongate slots (232) extending in parallel to an axial direction (A) of the autoinjector (10) from a proximal end (92) to a distal end of said sleeve (230).

44. The autoinjector according to one of claims 1 to 43, wherein the housing (12) comprises an inner body (80) and an outer body (82), with the cut-out (174, 174’) being arranged at the inner body (180).60

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