Cannabidiolic acid esters compositions and uses thereof
Ester derivatives of CBDA address the instability issue of CBDA by providing stable compounds with improved biological activity, effectively treating conditions like nausea and anxiety.
HK40135025APending Publication Date: 2026-07-17YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD +1
Patent Information
- Authority / Receiving Office
- HK · HK
- Patent Type
- Applications
- Current Assignee / Owner
- YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD
- Filing Date
- 2020-10-12
- Publication Date
- 2026-07-17
AI Technical Summary
Technical Problem
Cannabidiol acid (CBDA) is highly unstable, especially when heated, limiting its pharmacological applications, and there is a need for stable CBDA analogues with similar or more effective biological properties.
Method used
Development of ester derivatives of CBDA with specific alkyl, alkenyl, and alkynyl substituents, such as HU-580, which offer enhanced stability and maintain or improve biological activity.
Benefits of technology
The ester derivatives of CBDA provide stability while retaining or enhancing biological properties, including 5-HT1A receptor-mediated antinausea and anxiolytic effects, making them suitable for treating conditions like nausea, anxiety, and depression.
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Abstract
The present application relates to cannabidiol esters, compositions comprising them and their use in the treatment of a variety of different diseases, disorders and symptoms.
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