Detergent compositions for lice and methods for eliminating lice

Abstract

To provide detergent composition, etc. for lice that make lice fall off from the hair to prevent symptoms and diseases caused by the lice on the head such as itchiness, inflammation and infections.SOLUTION: Disclosed is a detergent composition for lice comprising siloxane, a surfactant and water, and when applied to hair infested with lice the composition makes the lice drop from the hair. The surfactant is at least one selected from an anionic surfactant, an amphoteric surfactant, and a nonionic surfactant, and preferably the surfactant is at least one selected from anionic surfactants or amphoteric surfactants.SELECTED DRAWING: None

Description

[Technical field]

[0001] The present invention relates to a lice cleansing composition which contains siloxane and water but has excellent compositional stability and which is capable of removing lice attached to hair, and a method for removing lice attached to hair. [Background technology]

[0002] Traditionally, lice have been known to infest the hair and clothing of nursery school children, kindergarten children, and elementary school children, and can also infect their family members. The blood-sucking behavior of lice can cause itching, inflammation, and even fever, and therefore various drugs have been known to eliminate lice.

[0003] For example, Patent Document 1 discloses a composition for eliminating lice that contains myristyl alcohol, isostearic acid, polyoxyethylene sorbitan trioleate (20 E.O.), polyethylene glycol monolaurate (HLB=13.7), polysorbate 80, polyoxyethylene stearyl ether, purified water, ethanol, isopropyl palmitate, dimethylpolysiloxane, liquid paraffin, dibutylhydroxytoluene, and α-tocopherol acetate.

[0004] Patent Document 2 discloses a composition containing isostearic acid, dimethylpolysiloxane, ethanol, and propylene glycol for eliminating lice and lice eggs. [Prior art documents] [Patent documents]

[0005] [Patent Document 1] JP 2013-139424 A [Patent Document 2] JP 2022-167308 A Summary of the Invention [Problem to be solved by the invention]

[0006] However, when the compositions for eliminating lice and the like disclosed in Patent Documents 1 and 2 are used, there is a problem in that, regardless of whether or not the lice attached to the hair are killed, it is unclear whether the lice can be detached from the hair when washed off, due to the strong adhesive power of the lice's claws.

[0007] Furthermore, the detergent composition is also required to have stability as a formulation, ie, not separate during storage.

[0008] Therefore, the present invention has been made in consideration of the above problems, and aims to provide a lice cleansing composition and the like that removes lice attached to hair in order to prevent symptoms and diseases such as itching, inflammation, and infections caused by lice on the head. [Means for solving the problem]

[0009] [1] That is, the lice cleansing composition according to the present invention is a lice cleansing composition that contains a siloxane, a surfactant, and water, and is characterized in that when applied to hair infested with lice, it removes the lice attached to the hair.

[0010] [2] The lice cleansing composition according to [1] above, characterized in that the surfactant is at least one selected from anionic surfactants, amphoteric surfactants, and nonionic surfactants.

[0011] [3] The lice cleansing composition according to [1] above, wherein the surfactant is at least one selected from an anionic surfactant or an amphoteric surfactant.

[0012] [4] The lice cleansing composition according to any one of [1] to [3], wherein the siloxane is at least one selected from the group consisting of dimethylpolysiloxane, diethylpolysiloxane, methylphenylpolysiloxane, hexamethylcyclotrisiloxane, octamethylcyclotetrasiloxane, and decamethylcyclopentasiloxane.

[0013] [5] The lice cleansing composition according to [2] or [3], characterized in that the anionic surfactant is at least one selected from the group consisting of carboxylic acid type, sulfonic acid type, sulfate ester type, and phosphate ester type.

[0014] [6] The lice cleansing composition according to [2] or [3], wherein the amphoteric surfactant is at least one selected from an amine oxide type and a betaine type.

[0015] [7] The lice cleansing composition according to [2] above, characterized in that it contains 0.1 to 50% by weight of the siloxane, 1 to 50% by weight of the nonionic surfactant, and 10 to 95% by weight of the water.

[0016] [8] The lice cleansing composition according to [3] above, characterized in that it contains 0.1 to 50% by weight of the siloxane, 1 to 50% by weight of the anionic surfactant, 1 to 50% by weight of the amphoteric surfactant, and 10 to 95% by weight of the water.

[0017] [9] The lice cleansing composition according to [1] or [2] above, characterized in that it contains an alcohol having 12 to 18 carbon atoms.

[0018]

[10] The method for removing lice of the present invention is a method for removing lice that comprises applying a cleaning composition containing a siloxane, a surfactant, and water to lice-infested hair, thereby removing the lice that have attached to the hair. Effect of the Invention

[0019] The lice cleansing composition of the present invention can remove lice attached to hair, thereby preventing symptoms and diseases such as itching, inflammation, and infections caused by lice on the head. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0020] Hereinafter, the embodiment of the lice cleanser composition of the present invention will be described in detail. Note that when a range is indicated in the description, it includes an upper limit and a lower limit.

[0021] The present invention relates to a cleansing composition containing siloxane, a surfactant, water, and the like as active ingredients for removing lice attached to hair.

[0022] The siloxane used in the present invention is a compound having silicon and oxygen and having a siloxane bond (Si-O-Si bond) as the main skeleton. For example, it is an organic compound obtained by hydrolysis and dehydration condensation of organoalkoxysilane.

[0023] Specifically, preferred siloxanes include linear siloxanes such as dimethylpolysiloxane, diethylpolysiloxane, and methylphenylpolysiloxane, and cyclic siloxanes such as hexamethylcyclotrisiloxane, octamethylcyclotetrasiloxane, and decamethylcyclopentasiloxane. It is more preferred that the siloxane has a linear skeleton and is oily at room temperature of 25° C. and has a kinetic viscosity of 1 to 500 mm at 25° C. 2 The siloxanes may be used alone or in combination of two or more.

[0024] In the pediculicide of the present invention, the content of siloxane is preferably 0.1 to 50% by weight, more preferably 0.5 to 45% by weight, and most preferably 1 to 40% by weight. When the content of siloxane is within this range, lice attached to hair can be removed, and symptoms and diseases such as itching, inflammation, and infections caused by lice on the head can be prevented.

[0025] The surfactant used in the present invention is an organic compound that has both a hydrophilic part and a lipophilic part and has surface activity. The surfactant is preferably at least one selected from an anionic surfactant, an amphoteric surfactant, and a nonionic surfactant. These surfactants can be used alone or in combination of two or more.

[0026] The anionic surfactant is an organic compound having an anionic hydrophilic site and having surface activity. Among them, at least one type selected from carboxylic acid type, sulfonic acid type, sulfate ester type, and phosphate ester type is preferable. The anionic surfactant may be not only a 100% pure liquid or solid compound, but also an aqueous solution obtained by diluting the compound with a predetermined amount of water.

[0027] Specifically, preferred carboxylic acid type anionic surfactants include sodium laurate, sodium stearate, sodium laureth-6 carboxylate (polyoxyethylene (4.5) lauryl ether sodium acetate), sodium lauroyl sarcosine, sodium octanoate, sodium decanoate, sodium myristate, sodium palmitate, coconut oil fatty acid (carbon number 8 to 18) sodium sarconate, polyoxyethylene tridecyl ether sodium acetate, etc. Preferred sulfonic acid type anionic surfactants include sodium lauryl sulfoacetate, sodium 1-hexanesulfonate, sodium 1-octane sulfonate, sodium 1-decanesulfonate, sodium 1-dodecanesulfonate, sodium toluenesulfonate, sodium cumenesulfonate, sodium naphthalenesulfonate, disodium naphthalene disulfonate, trisodium naphthalene trisulfonate, sodium alpha olefinsulfonate, etc. As the sulfate ester type anionic surfactant, sodium lauryl sulfate, sodium myristyl sulfate, sodium laureth sulfate (polyoxyethylene (3) lauryl ether sulfate), sodium cetyl sulfate, sodium cocoglyceryl sulfate (hydrogenated sodium coconut oil glyceryl sulfate), triethanolamine lauryl sulfate, ammonium lauryl sulfate, triethanolamine laureth sulfate, polyoxyethylene alkyl ether sulfate, etc. are preferred. As the phosphate ester type anionic surfactant, sodium lauryl phosphate, polyoxyethylene cetyl ether sodium phosphate (polyoxyethylene (5) cetyl ether sodium phosphate), lauryl phosphoric acid, potassium lauryl phosphate, etc. are preferred. The anionic surfactants may be used alone or in combination of two or more.

[0028] The amount of the anionic surfactant in the lice cleansing composition of the present invention is preferably 1 to 60% by weight, more preferably 2 to 55% by weight, and most preferably 3 to 50% by weight. When the content ratio of the anionic surfactant is within this range, lice attached to hair can be removed, and symptoms and diseases such as itching, inflammation, and infections caused by lice on the head can be prevented.

[0029] The amphoteric surfactant is an organic compound having anionic and cationic hydrophilic sites and having surface activity. Among them, at least one type selected from an amine oxide type and a betaine type is preferable. The amphoteric surfactant may be not only a 100% pure liquid or solid compound, but also an aqueous solution obtained by diluting the compound with a predetermined amount of water.

[0030] Specifically, preferred amine oxide-type amphoteric surfactants include lauryl dimethylamine oxide, alkyl dimethylamine oxide (N,N-dimethyl alkyl (C8-18) amine oxide), coconut alkyl dimethylamine oxide, decyl dimethylamine oxide, myristyl dimethylamine oxide, dihydroxyethyl lauryl amine oxide, and oleyl dimethylamine oxide. Preferred betaine-type amphoteric surfactants include lauryl dimethylamino acetate betaine, lauryl hydroxysulfobetaine, stearyl dimethylamino acetate betaine, dodecyl aminomethyl dimethylsulfopropyl betaine, coconut oil fatty acid (C8-18) amidopropyl betaine, 2-alkyl-N-carboxymethyl-N-hydroxyethyl imidazolinium betaine, and lauric acid amidopropyl betaine. The amphoteric surfactants may be used alone or in combination of two or more.

[0031] The amount of the amphoteric surfactant in the lice cleansing composition of the present invention is preferably 1 to 50% by weight, more preferably 5 to 48% by weight, and most preferably 10 to 45% by weight. When the content ratio of the amphoteric surfactant is within this range, lice attached to hair can be removed, and symptoms and diseases such as itching, inflammation, and infections caused by lice on the head can be prevented.

[0032] The nonionic surfactant is an organic compound having a hydrophilic portion that does not ionize and has surface activity, and is preferably polyoxyethylene alkyl ether, polyhydric alcohol fatty acid ester such as (poly)glycerin fatty acid ester, sorbitan fatty acid ester, sucrose fatty acid ester, fatty acid ester of polyoxyethylene-added polyhydric alcohol, fatty acid diethanolamide, etc. Specifically, as the nonionic surfactant, polyglycerin fatty acid ester such as polyoxyethylene lauryl ether, polyoxyethylene cetyl ether, polyoxyethylene stearyl ether, etc., decaglyceryl monomyristate, fatty acid ester of polyoxyethylene-added polyhydric alcohol such as polyoxyethylene sorbit tetraoleate, polyoxyethylene (20) sorbitan oleate, etc., fatty acid diethanolamide such as lauric acid diethanolamide, coconut oil fatty acid (carbon number 8 to 18) diethanolamide, etc. These surfactants can be used alone or in combination of two or more.

[0033] Among the above nonionic surfactants, those with an HLB calculated by Griffin's formula of 10 to 18 are preferred, and those with an HLB of 12 to 16 are more preferred. A nonionic surfactant with an HLB in the above range can remove lice attached to hair and prevent symptoms and diseases such as itching, inflammation, and infections caused by lice on the head. When two or more nonionic surfactants are used in combination, the sum of the HLBs obtained by multiplying the HLB of each nonionic surfactant by the blending ratio of each nonionic surfactant to the total nonionic surfactants is preferably in the above range.

[0034] The content of the nonionic surfactant in the lice cleansing composition of the present invention is preferably 1 to 50% by weight, more preferably 3 to 45% by weight, and most preferably 5 to 40% by weight. When the content of the amphoteric surfactant is within this range, lice attached to hair can be removed, and symptoms and diseases such as itching, inflammation, and infections caused by lice on the head can be prevented.

[0035] In the present invention, an alcohol having 12 to 18 carbon atoms can be added as necessary to prevent separation over time. Specifically, the alcohol having 12 to 18 carbon atoms used is preferably a straight-chain alcohol such as lauryl alcohol, myristyl alcohol, palmityl alcohol, stearyl alcohol, cetostearyl alcohol (a mixture of palmityl alcohol and stearyl alcohol), and more preferably an alcohol having a branched chain such as isostearyl alcohol. And, an unsaturated alcohol such as oleyl alcohol is preferred.

[0036] The amount of the alcohol having 12 to 18 carbon atoms in the lice cleansing composition of the present invention is preferably 0.1 to 20% by weight, more preferably 0.5 to 15% by weight, and most preferably 1 to 10% by weight. When the content of the alcohol having 12 to 18 carbon atoms is within this range, lice attached to hair can be removed while the siloxane and water do not separate even over time.

[0037] The water used in the present invention is preferably water that meets the Japanese Pharmacopoeia standards, and examples of such water include tap water, well water, and other common waters; purified water obtained by treating common water by distillation, ion exchange treatment using an ion exchange membrane, ultrafiltration treatment using an ultrafiltration membrane, or a combination of these; and sterile purified water obtained by sterilizing purified water by heating or the like.

[0038] The water content is preferably in the range of 10 to 95% by weight, more preferably in the range of 15 to 90% by weight, and most preferably in the range of 20 to 85% by weight. When the water content is in this range, lice attached to the hair can be removed, and symptoms and diseases such as itching, inflammation, and infections caused by lice on the head can be prevented.

[0039] Furthermore, in order to prevent corrosion such as deterioration due to oxidation of the preparation, antioxidants such as phenoxyethanol, vitamin C (ascorbic acid), vitamin E (α-tocopherol), BHT (dibutylhydroxytoluene), BHA (butylhydroxyanisole), sorbic acid, potassium sorbate, and sodium sulfite can be added. Also, methylparaben, paraoxybenzoic acid esters, etc. can be added for the purpose of preservation. Furthermore, l-menthol can be added to impart a refreshing feeling, various fragrances can be added to impart a scent, and even rinse components, colorants, and moisturizing agents such as propylene glycol and glycerin can be added. EXAMPLES

[0040] EXAMPLES The present invention will be specifically described below with reference to examples, but the present invention is not limited to the following examples.

[0041] <Example 1> In a Griffin beaker having a capacity of 200 ml at 20°C, 3 g of dimethylpolysiloxane as siloxane, 3 g of sodium polyoxyethylene tridecyl ether acetate as an anionic surfactant as a surfactant, 7 g of lauryl dimethylamine oxide as an amphoteric surfactant, 3 g of cetostearyl alcohol (a mixture of palmityl alcohol and stearyl alcohol) as an alcohol having 12 to 18 carbon atoms, and 84 g of purified water were mixed to prepare a composition of 100 g. Then, this was stirred and mixed until it became uniform to obtain a liquid composition. Note that the amount of each surfactant is the actual amount without dilution, and the same applies to the following examples and comparative examples.

[0042] <Examples 2 to 6> A liquid composition was obtained in the same manner as in Example 1, except that the weights of dimethylpolysiloxane as the siloxane, the weights of anionic surfactants such as polyoxyethylene tridecyl ether sodium acetate and polyoxyethylene alkyl ether sodium sulfate as surface active agents, the weights of lauryl dimethylamine oxide as an amphoteric surfactant, the weight of decaglyceryl monomyristate as a nonionic surfactant, the weights of cetostearyl alcohol as an alcohol having 12 to 18 carbon atoms, and the weight of purified water were used, all of which are shown in Table 1.

[0043] <Comparative Examples 1 to 7> A liquid composition was obtained in the same manner as in Example 1, except that the weights of dimethylpolysiloxane and decamethylcyclopentanesiloxane as siloxanes, the weights of lauryl dimethylamine oxide as amphoteric surfactants as surface active agents, the weights of decaglyceryl monomyristate as nonionic surfactants, the weight of polyoxyethylene lauryl ether, the weight of cetostearyl alcohol as an alcohol having 12 to 18 carbon atoms, and the weight of purified water were all as shown in Table 1.

[0044] Each composition obtained in each Example and Comparative Example was examined for its stability and its effect on removing lice from hair.

[0045] [Stability] The stability of each of the above compositions was confirmed as follows. That is, 50 ml of each of the above compositions was placed in a 100 ml screw tube and left to stand in an incubator set at a temperature of 50°C. Then, the state immediately after taking out after one week was visually observed, and the composition was evaluated as excellent if it had no change at all from before the start of the test, as ○ if it had almost no change from before the start of the test, as △ if it had changed slightly from before the start of the test but had not separated into an aqueous layer and an oil layer, as × if it had separated into an aqueous layer and an oil layer. The composition rated as ◎ or ○ was judged to be good, and the composition rated as △ or × was judged to be poor.

[0046] [Lice shedding from hair] The lice shedding properties of each of the above compositions were confirmed as follows. That is, first, 10 lice were placed on a dry hair bundle (length 5 cm, weight 1 g) and left to stand for 5 minutes to attach the lice to the hair bundle. Then, all the hair bundles with lice attached were immersed in 50 ml of each composition in a 100 ml beaker and left to stand for 5 minutes. Then, the hair bundles were lifted up above the liquid surface of each composition at a slow speed of 1 to 5 cm per second. Then, all the lifted hair bundles were immersed in 100 mL of 28 to 32°C water in a 200 ml beaker with a stirrer placed in it, and the water was stirred at 1.5 rpm to 2.5 rpm for 1 minute, and the hair bundles were lifted up above the liquid surface of each composition at a slow speed of 1 to 5 cm per second. The number of lice remaining on the removed hair bundle was counted, and the rate of lice that had fallen off from the hair bundle was calculated using the following formula (1). The test was carried out three times, and the arithmetic average of the three results was taken as the rate of lice falling off from the hair. Shedding rate (%) = {(number attached to hair - number remaining on hair) / number attached to hair} × 100 (Formula 1) A removal rate of less than 50% was judged as poor, meaning that the lice had difficulty removing from the hair; a removal rate of 50% to 70% was judged as good, meaning that the lice had difficulty removing from the hair; and a removal rate of 70% or more was judged as excellent, meaning that the lice had very easy time removing from the hair.

[0047] The compositions and the results of their effectiveness in terms of stability and shedding of lice from hair are shown in Table 1.

[0048] [Table 1]

[0049] As shown in Table 1, in Examples 1 to 6, the stability was excellent and the rate at which lice were removed from hair exceeded 80%. In contrast, in Comparative Examples 1 to 7, some were excellent in stability and some were poor, but in all cases the rate at which lice were removed from hair was below 50%, and the lice were difficult to remove from hair regardless of whether they were killed or not. From these results, it was found that the product contains siloxane, surfactant, and water, and when applied to hair with lice attached, it exerts the effect of removing lice attached to hair.

Claims

1. This lice cleansing composition contains a siloxane, a surfactant, and water, and is characterized in that when applied to hair to which lice are attached, it removes the lice attached to the hair.

2. 2. The lice cleansing composition according to claim 1, wherein the surfactant is at least one selected from the group consisting of anionic surfactants, amphoteric surfactants, and nonionic surfactants.

3. 2. The lice cleansing composition according to claim 1, wherein the surfactant is at least one selected from an anionic surfactant and an amphoteric surfactant.

4. The lice cleansing composition according to any one of claims 1 to 3, characterized in that the siloxane is at least one selected from the group consisting of dimethylpolysiloxane, diethylpolysiloxane, methylphenylpolysiloxane, hexamethylcyclotrisiloxane, octamethylcyclotetrasiloxane, and decamethylcyclopentasiloxane.

5. 4. The lice cleansing composition according to claim 2, wherein the anionic surfactant is at least one selected from the group consisting of carboxylic acid type, sulfonic acid type, sulfate ester type, and phosphate ester type.

6. 4. The lice cleansing composition according to claim 2, wherein the amphoteric surfactant is at least one selected from the group consisting of amine oxide and betaine surfactants.

7. The lice cleansing composition according to claim 2, characterized in that it contains 0.1 to 50% by weight of the siloxane, 1 to 50% by weight of the nonionic surfactant, and 10 to 95% by weight of the water.

8. The lice cleansing composition according to claim 3, characterized in that it contains 0.1 to 50% by weight of the siloxane, 1 to 50% by weight of the anionic surfactant, 1 to 50% by weight of the amphoteric surfactant, and 10 to 95% by weight of the water.

9. 3. The lice cleansing composition according to claim 1, further comprising an alcohol having 12 to 18 carbon atoms.

10. This method for removing lice comprises applying a cleaning composition containing a siloxane, a surfactant, and water to hair on which lice have adhered, thereby removing the lice from the hair.

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