Intraoral attachment cleaner

Abstract

To provide an intraoral attachment cleaner that has excellent deodorizing power and contains an oxygen-based bleaching agent and a fragrance, while delivering sufficient scent to the intraoral attachment after cleaning.SOLUTION: An intraoral attachment cleaner disclosed herein contains (A) at least one carbonate compound selected from the group consisting of carbonate, bicarbonate, and double salt of bicarbonate and carbonate, (B) acid, (C) oxygen-based bleaching agent, (D) fragrance, and (E) cyclodextrin.SELECTED DRAWING: None

Description

[Technical field]

[0001] The present disclosure relates to an intraoral instrument cleanser that has excellent deodorizing power and, while containing an oxygen bleach and a fragrance, is capable of imparting a sufficient fragrance to intraoral instruments after cleaning. [Background technology]

[0002] Dentures and other oral appliances are prone to bacteria, biofilms, and other deposits, and if left uncleaned, they can cause bad breath and may even contribute to oral diseases such as periodontal disease. Therefore, as part of oral care, it is essential to clean and keep oral appliances clean. Since bacteria and dirt adhering to oral appliances cannot be sufficiently removed by cleaning with a brush, cleaning with a detergent is important.

[0003] Cleaning of intraoral instruments with a detergent is generally performed by immersing the intraoral instruments in cleaning water prepared by adding the detergent to water. Conventionally, detergents for intraoral instruments have been formulated with surfactants and foaming agents (carbonic acid and acid), and are designed to enhance the cleaning effect by exerting chemical cleaning power due to surface activation and physical cleaning power due to foaming action when added to water.

[0004] In addition, in oral cavity instrument cleaners, bleaching agents are generally blended to impart a bleaching effect and improve cleaning and deodorizing power. For example, Patent Document 1 proposes a denture cleaner containing an oxygen bleaching agent. By blending an oxygen bleaching agent in the denture cleaner, it is possible to impart excellent deodorizing power to the denture cleaner.

[0005] In addition, in order to reduce the odor of the intraoral appliances and to make the wearer feel refreshed when reinstalling the intraoral appliance after cleaning, fragrances such as mint oil and l-menthol may be blended into the intraoral appliance cleanser. [Prior art documents] [Patent documents]

[0006] [Patent Document 1] JP 2005-272365 A Summary of the Invention [Problem to be solved by the invention]

[0007] However, when an oxygen-based bleach and fragrance are blended into an intraoral instrument cleanser, the fragrance is altered by the oxygen-based bleach in the intraoral instrument cleansing water prepared by adding the intraoral instrument cleanser to water, resulting in a decrease in the fragrance, and the intraoral instruments cannot be given a sufficient fragrance after cleaning.

[0008] An object of the present disclosure is to provide an intraoral instrument cleanser that has excellent deodorizing power and, while containing an oxygen bleach and a fragrance, is capable of imparting a sufficient fragrance to intraoral instruments after cleaning. [Means for solving the problem]

[0009] The present inventors have conducted extensive research to solve the above problems, and have unexpectedly found that by incorporating cyclodextrin into an intraoral instrument cleaner together with an oxygen bleach and a fragrance, not only is the deodorizing power improved, but also that in intraoral instrument cleaning water prepared by adding the intraoral instrument cleaner to water, the deterioration of the fragrance caused by the oxygen bleach is suppressed, and a sufficient fragrance can be imparted to intraoral instruments after cleaning. The present disclosure has been completed based on such findings and through further research.

[0010] That is, the present disclosure provides the inventions of the following aspects. Item 1. An intraoral instrument cleanser comprising: (A) at least one carbonate compound selected from the group consisting of carbonates, bicarbonates, and double salts of bicarbonates and carbonates; (B) an acid; (C) an oxygen bleaching agent; (D) a flavoring; and (E) a cyclodextrin. Item 2. The oral instrument cleanser according to Item 1, wherein the oxygen bleaching agent is monopersulfate. Item 3. The intraoral instrument cleanser according to item 1 or 2, further comprising (F) a bleaching activator. Item 4. The intraoral instrument cleanser according to Item 3, wherein the bleaching activator is tetraacetylethylenediamine. Item 5. The intraoral instrument cleanser according to any one of Items 1 to 4, which is a denture cleanser. Item 6. Use of a composition comprising (A) at least one carbonate compound selected from the group consisting of carbonates, bicarbonates, and double salts of bicarbonates and carbonates, (B) an acid, (C) an oxygen bleaching agent, (D) a flavoring, and (E) a cyclodextrin, for cleaning an intraoral appliance. Item 7. Use of a composition comprising (A) at least one carbonate compound selected from the group consisting of carbonates, bicarbonates, and double salts of bicarbonates and carbonates, (B) an acid, (C) an oxygen bleaching agent, (D) a flavoring, and (E) a cyclodextrin, as an intraoral instrument cleanser. Item 8. A method for cleaning an intraoral instrument, comprising immersing an intraoral instrument in water containing an intraoral instrument cleaner comprising: (A) at least one carbonate compound selected from the group consisting of carbonates, bicarbonates, and double salts of bicarbonates and carbonates; (B) an acid; (C) an oxygen-based bleaching agent; (D) a fragrance; and (E) cyclodextrin. Effect of the Invention

[0011] The intraoral instrument cleaner of the present disclosure has excellent deodorizing power due to the oxygen bleach and cyclodextrin, and while it contains an oxygen bleach and a fragrance, in the intraoral instrument cleaning water prepared by adding the intraoral instrument cleaner to water, it is possible to suppress the deterioration of the fragrance caused by the oxygen bleach, and therefore it is possible to impart a sufficient fragrance to the intraoral instrument after cleaning. As a result, the odor of the intraoral instrument after cleaning is reduced, and the wearer can feel a sufficient sense of refreshment when re-wearing the intraoral instrument after cleaning. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0012] In this specification, the notation X to Y regarding a numerical range means that the range is from X to Y.

[0013] In this specification, the term "oral appliance" refers to a dental appliance that needs to be worn and removed in the oral cavity, such as a complete denture, a partial denture, an orthodontic appliance, a retainer, and a mouthpiece.

[0014] 1. Mouth instrument cleaner The intraoral instrument cleaner of the present disclosure is characterized by containing (A) at least one carbonate compound selected from the group consisting of carbonates, bicarbonates, and double salts of bicarbonates and carbonates (hereinafter, sometimes referred to as component (A)), (B) acid (hereinafter, sometimes referred to as component (B)), (C) oxygen-based bleaching agent (hereinafter, sometimes referred to as component (C)), (D) flavoring (hereinafter, sometimes referred to as component (D)), and (E) cyclodextrin (hereinafter, sometimes referred to as component (E)). The intraoral instrument cleaner of the present disclosure will be described in detail below.

[0015] [Carbonate compounds] The intraoral instrument cleanser of the present disclosure contains, as component (A), at least one carbonate compound selected from the group consisting of carbonates, bicarbonates, and double salts of bicarbonates and carbonates. The carbonate compound is a known component constituting a foaming agent for intraoral instrument cleansers.

[0016] The carbonate salt is not particularly limited, but may be, for example, an alkali metal salt of carbonic acid such as sodium carbonate or potassium carbonate, preferably sodium carbonate. The hydrogen carbonate salt is not particularly limited, but may be, for example, an alkali metal salt of hydrogen carbonate such as sodium hydrogen carbonate or potassium hydrogen carbonate, preferably sodium hydrogen carbonate. The double salt of carbonate and hydrogen carbonate is not particularly limited, but may be, for example, sodium sesquicarbonate. The above-mentioned carbonate compounds may be used alone or in combination of two or more.

[0017] In the intra-oral instrument cleanser of the present disclosure, the content of component (A) is not particularly limited as long as sufficient carbon dioxide bubbles can be generated when cleaning intra-oral instruments, and can be, for example, 1 to 40% by weight, preferably 3 to 30% by weight, and more preferably 5 to 25% by weight.

[0018] [acid] The intraoral instrument cleanser of the present disclosure contains an acid as component (B). The acid is a component known to be a component constituting a foaming agent for intraoral instrument cleansers.

[0019] The acid may be an organic acid or an inorganic acid, preferably an organic acid. The organic acid may be, but is not particularly limited to, citric acid, tartaric acid, fumaric acid, malic acid, maleic acid, gluconic acid, succinic acid, salicylic acid, etc. The inorganic acid may be, but is not particularly limited to, phosphoric acid, sulfamic acid, etc. The above-mentioned exemplified acids may be used alone or in combination of two or more.

[0020] In the intra-oral instrument cleanser of the present disclosure, the content of component (B) is not particularly limited as long as sufficient carbon dioxide bubbles can be generated when cleaning intra-oral instruments, and can be, for example, 1 to 60% by weight, preferably 3 to 40% by weight, and more preferably 5 to 20% by weight.

[0021] In the intra-oral instrument cleanser of the present disclosure, the content of component (B) is not particularly limited, provided that it can react with component (A) in water to generate carbon dioxide. The content of component (B) per 100 parts by weight of component (A) is, for example, 50 to 500 parts by weight, preferably 75 to 420 parts by weight, and more preferably 80 to 320 parts by weight.

[0022] [Oxygen bleach] The intraoral instrument cleaner of the present disclosure contains an oxygen bleaching agent as component (C). The oxygen bleaching agent is a bleaching agent that converts HO2 -By including an oxygen bleach in an intraoral instrument cleanser, it is possible to impart excellent deodorizing power to the intraoral instrument cleanser.

[0023] The oxygen bleaching agent is not particularly limited as long as it is non-toxic and physiologically acceptable, and can be widely used as a cleaning agent for an oral instrument. Examples of the oxygen bleaching agent include percarbonate, perborate, persulfate, and monohydrogenpersulfate. The oxygen bleaching agents exemplified above may be used alone or in combination of two or more.

[0024] Specific examples of percarbonates include alkali metal salts of percarbonate such as sodium percarbonate and potassium percarbonate, ammonium percarbonate, and hydrates thereof. Specific examples of perborates include alkali metal salts of perborate such as sodium perborate and potassium perborate, ammonium perborate, and hydrates thereof. Specific examples of persulfates include alkali metal salts of persulfate such as sodium persulfate and potassium persulfate, ammonium persulfate, and hydrates thereof. Specific examples of monopersulfates include alkali metal salts of monopersulfate such as sodium persulfate and potassium persulfate, ammonium persulfate, and hydrates thereof. The oxygen bleaching agents exemplified above may be used alone or in combination of two or more. Of the oxygen bleaching agents exemplified above, from the viewpoint of further suppressing the decline of the fragrance of the fragrance in the washing water for the oral cavity-worn instrument, monopersulfate is preferred, and potassium monopersulfate is more preferred.

[0025] In the intraoral instrument cleanser of the present disclosure, the content of component (C) may be appropriately set within a range in which the desired deodorizing power can be exhibited, for example, 1 to 40% by weight, and from the viewpoint of enhancing the deodorizing power and further suppressing the decline in the fragrance of the fragrance in the intraoral instrument cleansing water, the content is preferably 2 to 30% by weight, and more preferably 3 to 20% by weight.

[0026] [Fragrance] The intraoral instrument cleanser of the present disclosure contains a flavor as component (D). The flavor is a component for imparting a scent to the intraoral instrument after cleaning.

[0027] The flavoring is not particularly limited, and a wide variety of oil-based flavorings that are commonly used in intraoral instrument cleaners can be used. Examples of flavorings include l-menthol, l-carvone, cinnamic aldehyde, orange oil, anethole, 1,8-cineole, methyl salicylate, eugenol, thymol, linalool, limonene, menthone, menthyl acetate, citral, camphor, borneol, pinene, spilanthol, ethyl acetate, ethyl butyrate, isoamyl acetate, hexanal, hexenal, methyl anthranilate, ethyl methylphenyl glycidate, benzaldehyde, vanillin, ethyl vanillin, furaneol, maltol, ethyl maltol, and gamma / delta decalactone. , gamma / deltaun decalactone, N-ethyl-p-menthane-3-carboxamide, menthyl lactate, ethylene glycol-l-menthyl carbonate, and other flavoring ingredients; peppermint oil, spearmint oil, eucalyptus oil, clove oil, thyme oil, sage oil, cardamom oil, rosemary oil, marjoram oil, lemon oil, nutmeg oil, lavender oil, parakress oil, and other natural essential oils; orange, apple, banana, strawberry, blueberry, melon, peach, pineapple, grape, muscat, wine, cherry, squash, coffee, brandy, yogurt, and other blended flavors. The above-exemplified flavorings may be used alone or in combination of two or more. Of the above-exemplified flavorings, natural essential oils are preferred, and mint oil is more preferred.

[0028] In the intra-oral instrument cleanser of the present disclosure, the content of component (D) may be appropriately set within a range that can impart the desired fragrance to the intra-oral instrument after cleaning, and is, for example, 0.1 to 5% by weight, and from the viewpoint of imparting an appropriate fragrance to the intra-oral instrument after cleaning, is preferably 0.2 to 3% by weight, and more preferably 0.3 to 2% by weight.

[0029] In the intra-oral instrument cleanser of the present disclosure, the content ratio of component (D) relative to component (C) is not particularly limited, and the content of component (D) relative to 100 parts by weight of component (C) is, for example, 0.5 to 25 parts by weight. From the viewpoint of further suppressing the decline in the fragrance of the flavoring in the intra-oral instrument cleansing water and from the viewpoint of imparting a sufficient fragrance to the intra-oral instrument after cleaning, the content is preferably 1 to 20 parts by weight, and more preferably 1.5 to 15 parts by weight.

[0030] [Cyclodextrin] The intraoral instrument cleaner of the present disclosure contains cyclodextrin as component (E). In the intraoral instrument cleaner of the present disclosure, cyclodextrin is a component that imparts excellent deodorizing power and suppresses the loss of fragrance of the fragrance caused by oxygen bleach in the intraoral instrument cleaner prepared by adding the intraoral instrument cleaner to water. Since cyclodextrin has an inclusion function, it is considered that in the intraoral instrument cleaner prepared by adding the intraoral instrument cleaner to water, cyclodextrin improves the deodorizing power by inclusion of malodorous components, and cyclodextrin inclusion of fragrance suppresses the deterioration of the fragrance caused by the oxygen bleach.

[0031] The cyclodextrin is not particularly limited, and examples thereof include those having 5 or more glucose atoms bound thereto, specifically, α-cyclodextrin having 6 glucose atoms bound thereto, β-cyclodextrin having 7 glucose atoms bound thereto, γ-cyclodextrin having 8 glucose atoms bound thereto, and cluster dextrin (registered trademark) which is a highly branched cyclic dextrin. Cluster dextrin can be commercially obtained from Nihon Shokuhin Kako Co., Ltd., Ezaki Glico Co., Ltd., etc. The above-mentioned cyclodextrins may be used alone or in combination of two or more kinds.

[0032] As the cyclodextrin, from the viewpoint of further improving the deodorizing power and effectively suppressing the decline in the fragrance of the fragrance in the intraoral instrument wash water, it is preferable to use at least one type selected from the group consisting of α-, β-, and γ-cyclodextrin, it is more preferable to use at least two types selected from the group consisting of α-, β-, and γ-cyclodextrin, and it is even more preferable to use three types of α-, β-, and γ-cyclodextrin. When α-, β-, and γ-cyclodextrin are used, the weight ratios of α-, β-, and γ-cyclodextrin are not particularly limited, but from the viewpoint of further improving the deodorizing power and more effectively suppressing the decline in the scent of the fragrance in the wash water for an intraoral instrument, when the total amount of α-, β-, and γ-cyclodextrins is taken as 100 parts by weight, the content of α-cyclodextrin is preferably 20 to 40 parts by weight, more preferably 25 to 35 parts by weight, the content of β-cyclodextrin is preferably 35 to 70 parts by weight, more preferably 45 to 60 parts by weight, and the content of γ-cyclodextrin is preferably 10 to 25 parts by weight, more preferably 15 to 20 parts by weight.

[0033] In the intra-oral instrument cleanser of the present disclosure, the content of component (E) may be adjusted as appropriate depending on the content of the fragrance, and is, for example, 0.01 to 5% by weight. From the viewpoints of further improving the deodorizing power, effectively suppressing the decline in the fragrance of the fragrance in the intra-oral instrument cleansing water, and imparting an appropriate fragrance to the intra-oral instrument after cleaning, the content is preferably 0.05 to 3% by weight, more preferably 0.1 to 2% by weight, even more preferably 0.1 to 1.5% by weight, still more preferably 0.1 to 1% by weight, and particularly preferably 0.2 to 0.7% by weight.

[0034] In the intra-oral instrument cleanser of the present disclosure, the content ratio of the (E) component to the (D) component is not particularly limited, and the content of the (E) component per 1 part by weight of the (D) component is, for example, 0.01 to 3 parts by weight. From the viewpoint of effectively suppressing the decline in the fragrance of the fragrance in the intra-oral instrument cleansing water and from the viewpoint of imparting an appropriate fragrance to the intra-oral instrument after cleaning, the content is preferably 0.05 to 2.5 parts by weight, more preferably 0.1 to 2.3 parts by weight, and even more preferably 0.1 to 2 parts by weight.

[0035] [Bleach activator] The intraoral instrument cleaner of the present disclosure may contain (F) a bleach activator (hereinafter, sometimes referred to as component (F)). The bleach activator is HO2 generated from an oxygen-based bleach in water. - It reacts with and produces organic peracids with a more effective bleaching effect.

[0036] The bleaching activator may be any known one without any particular limitation, and examples thereof include tetraacetylethylenediamine; alkanoyloxybenzenesulfonic acid or its salt having an alkanoyl group having 1 to 18 carbon atoms, preferably 8 to 12 carbon atoms; alkanoyloxybenzoic acid or its salt having an alkanoyl group having 1 to 18 carbon atoms, preferably 8 to 12 carbon atoms. Examples of the salt include alkali metal salts and ammonium salts. The bleaching activators exemplified above may be used alone or in combination of two or more. Among the bleaching activators exemplified above, tetraacetylethylenediamine is preferred from the viewpoint of excellent efficiency in generating an organic peracid.

[0037] In the intraoral instrument cleanser of the present disclosure, the content of component (F) may be adjusted appropriately depending on the content of the oxygen bleach, and is, for example, 0.01 to 5% by weight, and from the viewpoint of imparting excellent deodorizing power, is preferably 0.1 to 3% by weight, and more preferably 0.5 to 2% by weight.

[0038] [silica] The intraoral instrument cleaner of the present disclosure may contain (G) silica (hereinafter, may be referred to as (G) component). In the intraoral instrument cleaner of the present disclosure, silica is a component that impregnates a flavor and contributes to improving the storage stability of the flavor. Silica is a general term for silicon dioxide or a substance composed of silicon dioxide.

[0039] In the intra-oral instrument cleanser of the present disclosure, the content of component (G) may be adjusted as appropriate depending on the content of the fragrance, and is, for example, 0.01 to 5% by weight. From the viewpoint of further improving the storage stability of the fragrance, the content is preferably 0.1 to 3% by weight, more preferably 0.5 to 2% by weight, and even more preferably 0.5 to 1% by weight.

[0040] [Other ingredients] In addition to the components described above, the intra-oral instrument cleanser of the present disclosure may contain other components as necessary, to the extent that the effects of the present disclosure are not impaired.

[0041] Other additives that can be blended in the intraoral instrument cleanser of the present disclosure include magnesium oxide, surfactants, binders, deodorants, rust inhibitors, chelating agents, pH adjusters, enzymes, sweeteners, foam stabilizers, preservatives, antibacterial and germicidal agents, preservatives, lubricants, bulking agents, excipients, disintegrants, fluidizing agents, etc. The other components exemplified above may be blended alone or in any combination of two or more.

[0042] 2. Formulation of oral instrument cleanser The intraoral instrument cleanser of the present disclosure is in a solid form, specifically, molded into a powder, granule, or tablet, preferably molded into a granule or tablet, and most preferably molded into a tablet. When molded into a tablet, the weight per tablet is not particularly limited and may be appropriately set in consideration of ease of use, but it is desirable to set the weight per tablet to the amount required for one intraoral instrument cleansing.

[0043] The tablet-shaped intraoral instrument cleanser may be produced according to a known method. For example, the intraoral instrument cleanser of the present disclosure is produced by subjecting a mixture of the components (A) to (E) and other components added as necessary to a granule molding process such as granulation or a tablet molding process such as tableting.

[0044] 3. Uses of oral instrument cleaners The intra-oral instrument cleanser of the present disclosure is used as a cleaner for various intra-oral instruments, but is particularly suitable for use as a denture cleanser.

[0045] 4. How to use the oral instrument cleaner The intraoral instrument cleaner of the present disclosure is poured into water, heated as necessary, and an intraoral instrument (preferably a denture) to be cleaned is placed therein, whereby the intraoral instrument is cleaned by the foaming action caused by the reaction of the (A) and (B) components. The intraoral instrument cleaner of the present disclosure also exhibits excellent deodorizing and cleaning power because it contains the (C) component and the (E) component. The intraoral instrument cleaner of the present disclosure also contains the (E) component while containing the (C) component and the (D) component, and therefore can effectively suppress the loss of the fragrance of the perfume due to the oxygen bleach in the intraoral instrument cleaning water, and can impart a sufficient fragrance of the perfume to the intraoral instrument after cleaning. As a result, the odor of the intraoral instrument after cleaning is alleviated, and the wearer can feel a sufficient sense of refreshment when re-wearing the intraoral instrument after cleaning.

[0046] The water used when cleaning intra-oral instruments with the intra-oral instrument cleanser of the present disclosure is not particularly limited, but examples thereof include tap water, purified water, distilled water, and physiological saline water.

[0047] When cleaning an intraoral appliance using the intraoral appliance cleanser of the present disclosure, the intraoral appliance may be immersed in water and then the intraoral appliance cleanser of the present disclosure may be added, or the intraoral appliance may be immersed in water and then the intraoral appliance may be added.

[0048] In addition, in cleaning intraoral instruments, the ratio of the intraoral instrument cleaner of the present disclosure to water is appropriately set depending on the composition of the intraoral instrument cleaner of the present disclosure, the degree of dirt on the intraoral instrument to be cleaned, etc., but for example, the intraoral instrument cleaner may be usually about 1 to 10 parts by weight, preferably about 1 to 5 parts by weight, per 100 parts by weight of water. More specifically, in one cleaning of intraoral instruments, 100 to 200 mL of water is prepared, and 1 to 20 g, preferably 1 to 10 g, more preferably 1 to 5 g of the intraoral instrument cleaner of the present disclosure is added to this.

[0049] The temperature during cleaning of intraoral instruments may be about room temperature. The time for immersing intraoral instruments in the cleaning solution is usually about 5 minutes to 24 hours, preferably about 10 minutes to 12 hours, and more preferably about 30 minutes to 8 hours.

[0050] In addition, while cleaning the intraoral instruments, it is not necessary to stir the water to which the intraoral instrument cleanser has been added, but it may be stirred as necessary, and the intraoral instruments may be scrubbed with a cleaning tool such as a brush. EXAMPLES

[0051] The present invention will be described in more detail below with reference to examples, but the present disclosure is not limited to these examples.

[0052] The compositions of the cyclodextrins used in the following test examples and formulation examples are as follows. Cyclodextrin: a mixture of 13 parts by weight of α-cyclodextrin, 20 parts by weight of β-cyclodextrin, 7 parts by weight of γ-cyclodextrin, and 60 parts by weight of powdered sugar Mint flavor: Synthetic flavor Mixture of potassium sulfate, potassium hydrogen sulfate, and potassium monopersulfate (containing approximately 43% potassium monopersulfate by weight)

[0053] Test Example A tablet-shaped intraoral instrument cleaner was prepared with the composition shown in Table 1. Specifically, the composition obtained by mixing the components shown in Table 1 was tableted at 47 MPa using a 25φ diameter mold and a tableting machine (SMP-3012SK, small electric hydraulic pump, manufactured by Rikenki Co., Ltd.) to prepare tablet-shaped intraoral instrument cleaners weighing 2.65 g each. In Table 1, the units of the values ​​indicating the amount of each component in the composition are % by weight. In addition, in Table 1, the amount in the column for cyclodextrin indicates the total amount of α-, β-, and γ-cyclodextrin.

[0054] The prepared intraoral instrument cleansers were subjected to a deodorization test and a fragrance lingering test in the following manner.

[0055] <Deodorization test A> 200 μl of a malodorous aqueous solution containing methyl mercaptan (methyl mercaptan concentration: 3000 ppm) was placed in a glass container. In addition, one tablet of each of the intraoral instrument cleaners prepared in Examples 1 to 6, Comparative Examples 1 to 6, and Reference Example 1 was added to 180 ml of water at 25° C. to prepare a cleaning solution. Then, 400 μl of each of the cleaning solutions prepared was added to the glass container, and the mouth of the glass container was sealed with paraffin film. Then, the glass container was left to stand at 25° C. for 30 minutes. Thereafter, the concentration (ppm) of methyl mercaptan contained in the gas in the glass container was measured using a detector tube gas measuring instrument and a detector tube 71H (manufactured by Gastec Corporation). The results are shown in Table 1.

[0056] <Deodorization test B> A resin chip (20mm x 20mm x 1.5mm) of a denture material was immersed in the malodorous aqueous solution used in the deodorization test A. A cleaning solution was prepared by putting one tablet of each of the intraoral instrument cleaners prepared in Examples 1 to 6, Comparative Examples 1 to 6, and Reference Example 1 into a glass container containing 180ml of water at 25°C. The resin chip taken out of the malodorous aqueous solution was immersed in each of the prepared cleaning solutions and left to stand at 25°C for 3 hours to clean the resin chip. After cleaning, the resin chip was taken out and placed in a 10L airbag, which was filled with 1.5L of odorless air per 5 resin chips. After leaving to stand for 10 minutes at 25°C, the gas in the airbag was subjected to a sensory evaluation of the deodorizing properties. For the sensory evaluation of the deodorizing properties, a 6-level odor intensity method and a 9-level pleasantness / unpleasantness display method were adopted.

[0057] [6-level odor intensity method] The odor intensity of the gas inside the airbag was scored using a six-level odor intensity method (0: no odor, 1: barely detectable odor, 2: weak odor that is identifiable, 3: easily detectable odor, 4: strong odor, 5: awful odor). The odor intensity was scored by eight trained sensory evaluation monitors who had passed an olfactory blindness test, and the average score of the six monitors was used, excluding one monitor who scored the highest and one who scored the lowest. The results are shown in Table 1.

[0058] [9-level comfort level scale] The comfort level of the gas inside the airbag was scored using a 9-point comfort level scale (-4 points: extremely uncomfortable, -3 points: very uncomfortable, -2 points: uncomfortable, -1 point: slightly uncomfortable, 0 point: neither comfortable nor uncomfortable, 1 point: slightly comfortable, 2 points: comfortable, 3 points: very comfortable, 4 points: extremely comfortable). The comfort level was scored by the eight sensory evaluation monitors, and the average score of the six monitors was used, excluding one monitor who scored the highest and one monitor who scored the lowest. The results are shown in Table 1.

[0059] <Fragrance scent lingering test> The fragrance lingering test of the fragrance was performed by a three-point comparison method. Two cleaning solutions (reference solutions) were prepared by adding one tablet of the intraoral instrument cleaner prepared in Reference Example 1 to 180 ml of water at 25°C, and one cleaning solution (evaluation target solution) was prepared by adding one tablet of each of the intraoral instrument cleaners prepared in Examples 1 to 6 and Comparative Examples 1 to 6 to 180 ml of water at 25°C. Three hours after the preparation of the cleaning solutions, the eight sensory evaluation monitors compared the fragrance lingering using the two reference solutions and the one evaluation target solution. If five or more of the eight people judged the evaluation liquid to have a "decreased fragrance lingering" compared with the reference liquid, it was judged that they could distinguish between the two (they could recognize the decrease in fragrance lingering), and if four or fewer of the eight people judged it to be indistinguishable (they could not recognize the decrease in fragrance lingering). Evaluation liquids that were judged to be indistinguishable were rated "A" for fragrance lingering. Furthermore, those who judged it to be possible to distinguish between the two (they could recognize the decrease in fragrance lingering) were asked to answer the question "Is the difference in fragrance lingering a problem in terms of product performance?" on a two-point scale (problem, no problem), and the fragrance lingering was evaluated according to the following criteria. The results are shown in Table 1. B: The total number of people who answered "No problem" is 60% or more. C: The total number of people who answered "No problem" is less than 60%.

[0060] [Table 1]

[0061] The results in Table 1 show that the intraoral instrument cleansers of Examples 1 to 6, which contain cyclodextrin, have superior deodorizing effects compared to the intraoral instrument cleansers of Comparative Examples 1 to 6, which do not contain cyclodextrin, and can effectively inhibit the fading of the fragrance of the fragrance.

[0062] Prescription Examples Tablet-shaped intraoral instrument cleaners were prepared with the compositions shown in Tables 2 and 3. In Tables 2 and 3, the units of values ​​showing the amount of each component are % by weight. In addition, in Tables 2 and 3, the amount in the cyclodextrin column shows the total amount of α-, β-, and γ-cyclodextrin. All of the intraoral instrument cleaners had excellent deodorizing power and were able to impart a sufficient fragrance to the intraoral instruments after cleaning.

[0063] [Table 2]

[0064] [Table 3]

Claims

1. An intraoral instrument cleanser comprising: (A) at least one carbonate compound selected from the group consisting of carbonates, bicarbonates, and double salts of bicarbonates and carbonates; (B) an acid; (C) an oxygen bleaching agent; (D) a fragrance; and (E) a cyclodextrin.

2. 2. The intraoral instrument cleaner according to claim 1, wherein the oxygen bleaching agent is a monopersulfate salt.

3. The intraoral instrument cleaner according to claim 1 , further comprising (F) a bleaching activator.

4. The intra-oral instrument cleanser according to claim 3, wherein the bleach activator is tetraacetylethylenediamine.

5. The intraoral instrument cleanser according to any one of claims 1 to 4, which is a denture cleanser.

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