Motion sickness-suppressing fragrance composition

Abstract

To provide a motion sickness-suppressing fragrance composition that effectively suppresses motion sickness by utilizing a novel fragrance.SOLUTION: A motion sickness-suppressing fragrance composition contains an essential oil extracted from the wood and / or leaves of one or more species of Abies trees in the Pinaceae family.SELECTED DRAWING: None

Description

[Technical field]

[0001] The present invention relates to a fragrance composition for suppressing motion sickness. [Background technology]

[0002] Motion sickness is an unpleasant symptom caused by stimulation of the semicircular canals and vestibule due to the swaying, acceleration, and deceleration of a vehicle, which causes a disturbance in the sense of balance and autonomic nervous system, resulting in headaches, dizziness, nausea, etc.

[0003] Motion sickness affects many people of all ages, but it is particularly prevalent among children, and can be a problem when traveling in groups at school, on family trips, or when using vehicles.

[0004] For motion sickness, there are known methods for suppressing motion sickness using various drugs and aromas such as perfumes. For example, it is known that the sense of anxiety caused by motion sickness can be reduced by inhaling air containing β-potassium olefin, which is an aromatic substance (Patent Document 1).

[0005] As a method of utilizing fragrance, it is known that motion sickness can be suppressed by the fragrance of a fragrance composition containing, for example, 0.01% by weight or more of hexyl acetate and 0.2% by weight or less of geranyl acetate (Patent Document 2).

[0006] However, although the use of aromas to suppress motion sickness is less likely to cause side effects such as drowsiness compared to pharmaceutical anti-motion sickness medications, people have different preferences for aromas, so there was a need for technology to suppress motion sickness using a variety of aromas. [Prior art documents] [Patent documents]

[0007] [Patent Document 1] JP 2006-342062 A [Patent Document 2] JP 2017-178905 A Summary of the Invention [Problem to be solved by the invention]

[0008] Therefore, an object of the present invention is to provide an aromatic composition for suppressing motion sickness using a new aromatic fragrance in the suppression of motion sickness using an aromatic fragrance. [Means for solving the problem]

[0009] As a result of intensive research aimed at solving the above problems, the present inventors discovered that essential oils from specific trees suppress motion sickness, and thus completed the present invention.

[0010] That is, the present invention relates to an aromatic composition for suppressing motion sickness, which comprises essential oils from the wood and / or leaves of one or more types of trees of the genus Abies in the family Pinaceae.

[0011] The present invention also relates to an in-vehicle product, characterized in that the above-mentioned aroma composition for suppressing motion sickness is filled in an in-vehicle air freshener container. Effect of the Invention

[0012] The aromatic composition for suppressing motion sickness of the present invention can regulate the autonomic nervous system disorder and suppress motion sickness without side effects. In addition, the aromatic composition for suppressing motion sickness of the present invention can also suppress the odor of a vehicle. [Brief description of the drawings]

[0013] [Figure 1] FIG. 1 shows a microwave distillation apparatus. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0014] The aromatic composition for suppressing motion sickness of the present invention (hereinafter referred to as "the composition of the present invention") contains essential oils from the wood and / or leaves of one or more types of trees of the genus Abies of the family Pinaceae, and preferably contains only these essential oils as the active ingredient.

[0015] In the present invention, motion sickness refers to a condition in which, when riding in a vehicle such as a car or train, the shaking, acceleration, deceleration, etc. of the vehicle stimulates the semicircular canals or the vestibule, and furthermore, an unpleasant smell or odor inside the vehicle evokes memories of past motion sickness, causing a disturbance in the sense of balance and autonomic nerve dysfunction, resulting in headaches, dizziness, nausea, etc., which can be suppressed by the composition of the present invention. In the present invention, suppression of motion sickness refers to preventing or alleviating the symptoms of motion sickness.

[0016] Examples of trees of the genus Abies of the Pinaceae family include, but are not limited to, Abies sachalinensis, Fir, Abies salicina, Abies mariesii, Abies veitchii, Abies veitchii, Balsam fir, Abies mitsunense, White fir, Fir amabilis, Abies sachalinensis, California red fir, Grand fir, Noble fir, etc. One or more types of trees of the genus Abies of the Pinaceae family can be used. Among these trees of the genus Abies of the Pinaceae family, Abies sachalinensis and Fir are preferred, and Abies sachalinensis is more preferred.

[0017] The part of the tree of the genus Abies of the family Pinaceae is the interxylem and / or the leaf, preferably the leaf. The essential oil of the xylem and / or the leaf of the tree of the genus Abies of the family Pinaceae is not particularly limited as long as it is an essential oil obtained from one or more kinds of xylem and / or the leaf of the tree of the genus Abies of the family Pinaceae, but is preferably, for example, an oil fraction (essential oil) of the distillate obtained by subjecting the raw material to reduced pressure steam distillation. The oil fraction of the reduced pressure steam distillate has a refreshing fragrance and is highly palatable, even without the effort of concentration, purification, etc.

[0018] Heating during distillation may be performed using a general heater or the like, but microwave heating is preferred in terms of heating efficiency, and it is particularly preferred to heat by irradiating microwaves without adding water. By irradiating microwaves, water molecules contained in the plant are directly heated to generate water vapor, which acts as a mobile phase to distill the volatile components in the plant, so this distillation method is considered to include an element of reduced pressure distillation due to the boiling point of the volatile components, and an element of steam distillation.

[0019] Such a distillate by microwave irradiation can be obtained, for example, by using a microwave distillation apparatus described in the pamphlet of International Publication WO2010 / 098440. This microwave distillation apparatus is shown in Figure 1. In Figure 1, 1 is a microwave distillation apparatus, 2 is a distillation tank, 3 is a microwave heating device, 4 is a stirring bar, 5 is an air inlet pipe, 6 is a distillate outlet pipe, 7 is a cooling device, 8 is a heating control device, 9 is a pressure reducing pump, 10 is a pressure regulating valve, 11 is a pressure control device, 12 is a distillation target, and 13 is a distillate.

[0020] In this apparatus 1, the raw material, fir tree of the family Pinaceae, which is the object of distillation 12, is placed in a distillation tank 2, and while stirring with stirring blades 4, microwaves are radiated from a microwave heating device 3 mounted on the top surface of the distillation tank 2 to heat the raw material. This distillation tank 2 is connected to an air inlet 5 and a distillate outlet pipe 6. The air inlet pipe 5 introduces air or an inert gas such as nitrogen gas into the distillation tank 2, and this airflow is introduced from the bottom of the distillation tank 2. The distillate outlet pipe 6 leads the distillate from the raw material out from the top of the distillation tank 2.

[0021] The temperature and pressure inside the distillation tank 2 are measured by a temperature sensor and a pressure sensor (neither shown) attached thereto, and are adjusted via a heating control device 8, a pressure control device 11, and a pressure regulating valve 10, respectively.

[0022] The gaseous distillate discharged from the distillation tank 2 via the distillate outlet pipe 6 is converted into a liquid by the cooling device 7, and is obtained as a distillate 13. This distillate 13 contains an oil fraction 13a and an aqueous fraction 13b, of which the oil fraction (essential oil) 13a is separated and used as the active ingredient of the composition of the present invention.

[0023] The distillation may be performed with a pressure in the distillation tank 2 of 3 to 95 kPa, preferably 3 to 40 kPa, and more preferably 3 to 20 kPa, and the steam temperature is 40°C to 100°C. If the pressure is 3 kPa or less, the increase in the vapor pressure of the volatile components in the plant is suppressed, and the vacuum distillation element due to the boiling point of each component becomes dominant rather than the steam distillation element, and the components with the lower boiling points flow out in order, which is undesirable in that the extraction of components with a higher boiling point than water is not performed efficiently and that a large amount of high-boiling components with low repellency and poor aroma preference are extracted. If the pressure is 95 kPa or more, the temperature of the raw material increases, which is undesirable in that energy loss is large and oxidation of the raw material is promoted.

[0024] The distillation time may be about 0.2 to 8 hours, preferably about 0.4 to 6 hours. If it is less than 0.2 hours, many unextracted components in the plant remain, and if it is more than 8 hours, the raw material becomes almost dry, which may reduce the extraction efficiency.

[0025] Furthermore, the gas introduced into the distillation tank 2 may be air, but is preferably an inert gas such as nitrogen gas, helium gas, or argon gas, and the flow rate thereof may be about 0.001 to 0.1 times the volume of the distillation tank 2 per minute.

[0026] The oil fraction (essential oil) of the reduced pressure steam distillate of the xylem and / or leaves of trees of the genus Abies in the family Pinaceae obtained as described above can be used as is, but if necessary, it may be further concentrated or purified by conventional methods before use.

[0027] The composition of the present invention contains essential oil from the wood and / or leaves of trees of the genus Abies and the family Pinaceae in an amount of 5% by mass (hereinafter simply referred to as "%) or more, preferably 5 to 30%.

[0028] The composition of the present invention may contain conventionally known ingredients such as fragrances, surfactants, solvents, etc. in the form described below, so long as the effects of the essential oil of the wood and / or leaves of the above-mentioned trees of the genus Abies of the family Pinaceae are not impaired. The composition of the present invention may also be supported on a known carrier such as wood, paper, cloth, resin, gel, etc.

[0029] The composition of the present invention can be used as it is for suppressing motion sickness, but it is preferable to use it in the form of a product.The form of the product is not particularly limited, but since it is for suppressing motion sickness, for example, the composition of the present invention is filled in an air conditioner louver air freshener container (a type of container in which the air freshener volatilizes with the wind of the air conditioner), a standing air freshener container, or other air freshener container for air conditioners, a product for application in which the composition of the present invention is impregnated into a sticker or tape for application, a product for spraying in which the composition of the present invention is filled in a spray container for spraying, or a product for application on the human body in which the composition of the present invention is filled in a container for application, etc. are preferable among these products.The composition of the present invention is preferably a product for application in an automobile.

[0030] When making it into an in-vehicle product, for example, the composition of the present invention may be prepared by combining the essential oil alone or the essential oil with a fragrance, a surfactant, a solvent, etc., and then filled into an in-vehicle air freshener container such as an air freshener container for air conditioner louvers, a free-standing air freshener container, etc. When filling into an in-vehicle air freshener container, the composition of the present invention may be supported on the above-mentioned known carrier, if necessary.

[0031] When preparing a patch product, for example, the essential oil alone or a combination of the essential oil with a fragrance, a solvent, etc. may be used as the composition of the present invention, which may then be impregnated into a tape, sticker, or the like to be applied.

[0032] When preparing a product for spraying, for example, the composition of the present invention may be made from an essential oil alone or a combination of an essential oil with a fragrance, a surfactant, a solvent, water, etc., and then filled into a spray container or the like for spraying.

[0033] When making a product to be applied to the human body, for example, the composition of the present invention may be made from an essential oil alone or a combination of an essential oil with a fragrance, a surfactant, a solvent, a moisturizer, etc., and then filled into a container for application.

[0034] The composition of the present invention described above can suppress motion sickness by volatilizing in the air, attaching to clothing, spraying in the air, etc., and inhaling through the human nasal cavity, etc. In particular, children may be triggered by the smell of a vehicle, but the composition of the present invention can also suppress the smell of a vehicle, so the composition of the present invention is preferable for suppressing motion sickness in children. Furthermore, since it is not a sickness suppressant that uses a drug, it does not cause side effects such as drowsiness.

[0035] In order for the composition of the present invention to exert its effect of suppressing motion sickness, it is sufficient that the composition of the present invention is dispersed in an amount sufficient to enable people in the vehicle to constantly sense the aroma of the composition, and there is no particular limitation on the amount. For example, in the case of a four-seater vehicle, the composition of the present invention should be dispersed in an amount of 0.005 g or more per hour inside the vehicle. EXAMPLES

[0036] The present invention will be described in detail below with reference to examples, but the present invention is not limited to these examples in any way.

[0037] Manufacturing Example 1 Preparation of Abies sachalinensis essential oil: Todomatsu leaves were crushed with a crushing grinder (manufactured by KYB Manufacturing Co., Ltd.), and about 50 kg of the crushed material was put into the distillation tank of a microwave steam distillation apparatus (Figure 1). The pressure in the distillation tank was kept under reduced pressure of about 20 KPa (steam temperature was about 67°C) while stirring, and microwaves were irradiated for 1 hour to obtain a distillate, and the oily fraction (hereinafter referred to as "Todomatsu essential oil") was separated. The amount of Todomatsu essential oil obtained was 180 mL, which was 0.34% of the input sample. In the subsequent tests, this Todomatsu essential oil was used as an aromatic composition for suppressing motion sickness.

[0038] Example 1 Preparation of in-vehicle products: The fir essential oil (aromatic composition for suppressing motion sickness) prepared in Production Example 1 was placed in an air conditioner louver fragrance container (a container similar to SHALDAN My Aroma Aroma for CAR (manufactured by S.T. Co., Ltd.)) to obtain an in-car product.

[0039] Test Example 1 Motion Sickness Suppression Test: The in-car product prepared in Example 1 was installed on the air conditioner louvers of a car owned by a parent whose child is prone to car sickness. After that, the parent had the child use the car as usual for two weeks, and during that time, adults were asked to evaluate the child's motion sickness and the vehicle odor (smell inside the car) according to the following criteria. The evaluation items and evaluation criteria are described below. These results are shown in Table 1. In addition, adults were asked to freely evaluate their impressions of using this in-car product. The results are shown in Table 2.

[0040] [Table 1]

[0041] [Table 2]

[0042] <Symptoms of motion sickness in children> Evaluation Content ○: Improved compared to usual. -: Same as usual. ×: Worse than usual.

[0043] <Evaluation of vehicle odor> Evaluation Content ○: The smell of the vehicle has improved and is no longer bothersome. -: Same as usual. ×: The smell of the vehicle has worsened.

[0044] From the above results, it was found that the aromatic composition for suppressing motion sickness of the present invention improves the symptoms of motion sickness in children and also suppresses the odor of vehicles.

[0045] Example 2 Preparation of in-vehicle products: The fir essential oil (aromatic composition for suppressing motion sickness) prepared in Production Example 1 was impregnated into 30 cube-shaped pieces of wood with sides measuring 12 mm, which were then placed in a free-standing air freshener container with a partially open top to obtain an in-car product.

[0046] Example 3 Preparation of patch product: The nonwoven fabric side of the nonwoven fabric seal was impregnated with the Abies sachalinensis essential oil (aromatic composition for suppressing motion sickness) prepared in Production Example 1 to obtain a patch product.

[0047] Example 4 Preparation of spray product: The spray agent having the following formulation containing the todomatsu essential oil prepared in Production Example 1 was placed in a commercially available 150 ml trigger-type spray container to obtain a spray-type spray product. Active ingredient: Todomatsu essential oil 10g Solvent: Ethanol 10g Surfactant: 3g Ion exchange water: 77g [Industrial Applicability]

[0048] The fragrance composition for suppressing motion sickness of the present invention is capable of suppressing motion sickness. [Explanation of symbols]

[0049] 1 … … Microwave distillation apparatus 2 … … Distillation tank 3 … … Microwave heating device 4 … … Stirring splashes 5 … … Air flow inlet pipe 6 … … Distillate outlet pipe 7 … … Cooling device 8 … … Heating control device 9 … … Pressure reducing pump 10 ... ... Pressure regulating valve 11 ... ... Pressure control device 12 … … Object to be distilled 13 … … Extract 13a … … Oil fraction (essential oil) 13b … … Aqueous fraction

Claims

1. An aromatic composition for suppressing motion sickness, comprising essential oils from the wood and / or leaves of one or more kinds of trees of the genus Abies in the family Pinaceae.

2. 2. The aromatic composition for suppressing motion sickness according to claim 1, wherein the tree of the genus Abies of the family Pinaceae is selected from the group consisting of Abies sachalinensis, Fir, Abies salicina, Abies veitchii, Abies mariesii, Veitchii veitchii, Balsam fir, Abies mitsinoides, White fir, Amabilis fir, Abies sachalinensis, California red fir, Grand fir and Noble fir.

3. 2. The aromatic composition for suppressing motion sickness according to claim 1, wherein the content of essential oil from the wood and / or leaves of a tree of the genus Abies in the family Pinaceae is 5% by mass or more.

4. 4. An in-vehicle product comprising an in-vehicle air freshener container filled with the aroma composition for suppressing motion sickness according to any one of claims 1 to 3.

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