Oral composition and producing method thereof

Abstract

To provide an oral composition containing tamarind seed extract.SOLUTION: An oral composition contains tamarind seed extract (A) and pomegranate extract (B). The oral composition is effective in improving joint pain, alleviating lower back pain, reducing physical fatigue, and decreasing neutral fat due to the components contained, and can be used as a functional food or supplement.SELECTED DRAWING: Figure 1

Description

[Technical field]

[0001] The present invention relates to oral compositions containing tamarind seed extract. [Background technology]

[0002] Due to the increasing health consciousness in recent years, taking tablet-type supplements containing ingredients that are useful for improving health has become widespread.

[0003] On the other hand, tamarind is used for food, including its fruits and seeds, and is attracting attention for its health benefits based on the abundant nutritional components contained in tamarind. However, tamarind seed extract is known to be a highly sticky food ingredient, and when produced as a tablet-type supplement, there are problems in that it is sticky, making it inconvenient to handle, and difficult to compress into tablets. As a method for tableting highly adhesive food materials, Patent Document 1 discloses a method in which a lubricant such as calcium stearate is sprayed onto the tableting surface of a tablet press and then the material is tableted. [Prior art documents] [Patent documents]

[0004] [Patent Document 1] JP 2023-054786 A Summary of the Invention [Problem to be solved by the invention]

[0005] As described above, in Patent Document 1, a lubricant is sprayed onto the tableting surface of a tablet press before tableting. However, this requires a process such as spraying, which complicates the work process and leaves room for improvement.

[0006] Under such circumstances, an object of the present invention is to provide an oral composition which contains tamarind seed extract, yet is easy to handle and can be easily taken on a daily basis. [Means for solving the problem]

[0007] As a result of intensive research aimed at solving the above problems, the present inventors discovered that the following invention meets the above object, and thus completed the present invention.

[0008] That is, the present invention relates to the following inventions. <1> An oral composition containing a tamarind seed extract (A) and a pomegranate extract (C). <2> Further, it contains turmeric extract (C) and / or moringa extract (D). <1> The oral composition according to claim 1. <3> It is a tablet <1> or <2> The oral composition according to claim 1. <4> It is a functional food. <1> from <3> 2. The oral composition according to claim 1 , <5> It has one or more effects selected from the group consisting of an effect of improving joint pain, an effect of improving lower back pain, an effect of reducing physical fatigue, and an effect of reducing neutral fat. <4> The oral composition according to claim 1.

[0009] <1a> A step of mixing a tamarind seed extract (A) and a pomegranate extract (B) to obtain a mixture; compressing the mixture into tablets; A method for producing an oral composition comprising: Effect of the Invention

[0010] According to the present invention, there is provided an oral composition which contains tamarind seed extract, yet is easy to handle and can be easily taken on a daily basis. [Brief description of the drawings]

[0011] [Figure 1] FIG. 1 is a diagram showing an outline of the shape of a tablet using the oral composition of the present invention. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0012] The present invention will be described in detail below with reference to examples, but the present invention is not limited to the following examples, and can be modified as desired without departing from the gist of the present invention. In this specification, the word "~" is used as an expression including the numerical value or physical quantity before and after it. In this specification, the expression "A and / or B" includes "A only," "B only," and "both A and B."

[0013] The present invention relates to an oral composition containing a tamarind seed extract (A) and a pomegranate extract (B) (hereinafter, sometimes referred to as "the oral composition of the present invention").

[0014] The oral composition of the present invention is characterized by its easy handling even though it contains the highly sticky tamarind seed extract by containing the tamarind seed extract (A) and the pomegranate extract (B). Although the details of the reason are not completely clear, as shown in the examples described below, by containing the tamarind seed extract (A) and the pomegranate extract (B) in the oral composition of the present invention, the composition is easy to handle and can be molded into tablets that are easy to take on a daily basis.

[0015] The oral composition of the present invention will now be described in detail.

[0016] In this specification, tamarind seed extract (A) may be referred to as "component (A)" and pomegranate extract (B) may be referred to as "component (B)." In addition, in the present invention, the term "extract" is a general concept that refers to a form in which the content of active ingredients is increased by squeezing or solvent extraction of the target raw material plant, or a product thereof that has been pretreated (dried, chopped, etc.) as necessary.

[0017] <Ingredient (A): Tamarind seed extract> Tamarind (scientific name: Tamarindus indica L.) is a plant belonging to the genus Tamarindus in the family Fabaceae. It is cultivated in subtropical and tropical regions such as India, Southeast Asia, and the Americas, and is easily available in these regions. The tamarind seed extract is an extract obtained by subjecting the seeds of tamarind to an extraction treatment, and may be prepared from the part of the plant to be used as the raw material for extraction, or may be a commercially available product.

[0018] The oral composition of the present invention may contain tamarind seeds (the seed part of tamarind) and may contain other parts as long as the purpose of the present invention is not impaired. Furthermore, the shape, structure and size of the tamarind seeds are not particularly limited and may be appropriately selected depending on the purpose.

[0019] The tamarind seeds may be in a raw state as they are, but may be subjected to pretreatment such as crushing, cutting, steaming, rolling, drying, roasting, etc., as necessary.

[0020] Tamarind seeds may be used for the solvent extraction as is without prior treatment, but are usually used in a fine powder form by slicing, crushing, squeezing or grating to increase the efficiency of the extraction.

[0021] The tamarind seed extract includes any of an extract obtained by using tamarind seeds as an extraction raw material, a dilution or concentration of the extract, or a crude or purified product thereof. In addition, a dried product obtained by drying the extract is also considered to be an extract.

[0022] When the tamarind seed extract is obtained by solvent extraction, the extraction solvent is not particularly limited as long as it is one that is usually used for oral compositions, and examples thereof include water, ethanol, or a mixture thereof.

[0023] The extraction solvent may contain additives within the range that does not impair the effects of the present invention. For example, pH adjusters, viscosity adjusters, etc. may be included.

[0024] The amount of the extraction solvent relative to the raw material tamarind seeds is not particularly limited, but is usually about 1 to 100 times the amount of the tamarind seeds by weight.

[0025] The extraction method is not particularly limited, and an example of a method for producing a tamarind seed extract includes a method in which tamarind seeds are brought into contact with an extraction solvent and stirred in the extraction solvent for a certain period of time until the active ingredients are sufficiently extracted from the tamarind seeds. The extraction time is appropriately selected taking into consideration the type of extraction solvent and the ratio of tamarind seeds to the extraction solvent, and when the extraction solvent is a mixed solvent of water and ethanol, the extraction time can be, for example, 1 to 24 hours.

[0026] The extraction process is carried out at room temperature to avoid deterioration of quality, but may be carried out under heated conditions to increase the efficiency of extraction. If necessary, the solvent may be removed by vacuum concentration or freeze-drying to increase the proportion of active ingredients in the tamarind seed extract.

[0027] In addition, filtration or centrifugation may be performed to remove residues contained in the extract. The obtained extract may be used as is, or may be subjected to treatments such as dilution, concentration, drying, purification, etc. according to conventional methods. If necessary, the solvent may be removed by concentration / drying such as vacuum concentration, freeze drying, spray drying, etc.

[0028] In addition, tamarind seeds, which are the raw material for the tamarind seed extract, contain a large amount of polyphenols, particularly proanthocyanidins, and therefore the oral composition of the present invention is expected to have an anti-inflammatory effect (such as reducing knee joint pain) due to the tamarind seed extract contained therein.

[0029] <Ingredient (B): Pomegranate extract> Pomegranate (scientific name: Punica granatum) is a plant belonging to the genus Punica in the family Pomegranate, and is distributed in Iran, Afghanistan, West Pakistan, etc., and is easily available in these areas. The pomegranate extract is an extract obtained by subjecting pomegranate, which is a plant raw material, to an extraction treatment, and may be prepared from the extraction part used as the extraction raw material, or a commercially available product may be used.

[0030] The part of pomegranate to be extracted is not particularly limited and can be appropriately selected depending on the purpose, and examples thereof include leaves, branches, bark, trunk, stem, fruit, peel, flower, above-ground part, root, etc. These may be used alone or in combination of two or more kinds. The shape, structure, and size of the pomegranate extract raw material are not particularly limited and can be appropriately selected depending on the purpose.

[0031] The method for processing the extracted parts of pomegranate is not particularly limited and can be appropriately selected depending on the purpose. For example, it can be carried out in the same manner as in the above <Component (A): Tamarind seed extract>.

[0032] The form of pomegranate extract, extraction, extract treatment, and extract purification method are not particularly limited and can be appropriately selected depending on the purpose. For example, they can be carried out in the same manner as in the above <Component (A): Tamarind seed extract>.

[0033] In addition, pomegranate, which is the raw material of pomegranate extract, contains a lot of polyphenols, especially ellagic acid, so the oral composition of the present invention is expected to have the effect of reducing body weight, body fat, blood neutral fat, visceral fat, etc. due to the pomegranate extract contained therein.

[0034] (Mixing ratio) The blending ratio of component (A) and component (B) can be appropriately set within a range that does not impair the object of the present invention. When the total of the oral composition of the present invention is taken as 100% by weight, it is preferable that the blending ratio of each component is 10 to 35% by weight for component (A) and 1 to 70% by weight for component (B). In this case, the blending ratio (weight ratio) of component (A) to component (B) can be, for example, 1:0.05 to 1:25.

[0035] The oral composition of the present invention preferably contains, in addition to the tamarind seed extract (A) and the pomegranate extract (B), a turmeric extract (C) and / or a moringa extract (D). In this specification, turmeric extract (C) may be referred to as "ingredient (C)" and moringa extract (D) may be referred to as "ingredient (D)."

[0036] <Ingredient (C): Turmeric extract> Turmeric (scientific name: Curcuma longa) is a plant belonging to the genus Curcuma in the family Zingiberaceae. It is distributed in tropical Asia and cultivated in India, Okinawa, southeastern China, and Southeast Asia, and is easily available in these regions. The turmeric extract is an extract obtained by subjecting turmeric, which is a plant raw material, to an extraction process. The turmeric extract may be prepared from the part of the plant used as the raw material for extraction (such as the root, stem, or fruit), or a commercially available product may be used.

[0037] In addition, turmeric, which is the raw material of turmeric extract, contains a lot of polyphenols, especially curcumin, so the oral composition of the present invention is expected to have an anti-inflammatory effect (such as reducing knee joint pain) due to the turmeric extract contained therein.

[0038] <Ingredient (D): Moringa extract> Moringa (scientific name: Moringa oleifera Lam.) is a plant belonging to the genus Moringa in the family Moringaceae. It is mainly cultivated in tropical and subtropical regions and is easily available in these regions. Moringa extract is an extract obtained by subjecting moringa, which is a plant raw material, to an extraction process. The extract may be prepared from the part of the plant used as the raw material for extraction (seeds, bark, flesh, etc.), or a commercially available product may be used.

[0039] In addition, Moringa, the raw material of Moringa extract, contains a large amount of glucosinolate glucomoringin, and therefore, the oral composition of the present invention is expected to have an antioxidant effect (such as reducing fatigue and lower back pain) due to the Moringa extract contained therein.

[0040] The oral composition of the present invention preferably contains component (C) and / or component (D), either one of them or both of them may be contained. The amounts of component (C) and component (D) may be appropriately determined within a range that does not impair the object of the present invention. However, it is preferable that the respective blending ratios of component (C) and component (D) are 0.1 to 2% by weight and 0.1 to 30% by weight, respectively, when the total amount of the oral composition of the present invention is 100% by weight.

[0041] As described above, the above components may be extracted from plant materials or commercially available products. When using commercially available products, each component may be used alone or in combination of two or more. When a commercially available product is a combination of two or more components, the content of each component is usually determined according to the blending concentration of the commercially available product.

[0042] <Other ingredients> The oral composition of the present invention may contain other ingredients in addition to the tamarind seed extract (component (A)), pomegranate extract (component (B)), and optionally the turmeric extract (component (C)) and moringa extract (component (D)), provided that the ingredients do not impair the objective of the present invention. The other components are not particularly limited and can be appropriately selected depending on the form of the oral composition of the present invention, and may include, for example, other food components (such as plant extracts), optional additive components, etc. Examples of optional additive components include excipients, binders, disintegrants, lubricants, stabilizers, colorants, etc. These may be used alone or in combination of two or more.

[0043] The oral composition of the present invention can be produced by mixing a tamarind seed extract (A) with a pomegranate extract (B) to obtain a mixture. If necessary, the method may further include a step of mixing a turmeric extract (C), a moringa extract (D), or other ingredients. The oral composition of the present invention may be produced in any manner, and the above-mentioned components may be mixed in any order, depending on the dosage form, etc.

[0044] When the oral composition of the present invention is tableted, it can be produced by a process of tableting the mixture obtained by the above-mentioned production method to form tablets. After the tableting process, if necessary, a process of forming a coating layer on the surface of the plain tablet obtained in the tableting process (coating process) may be further included. The method for producing the tablets in the present invention is arbitrary, and any known tableting method may be appropriately selected.

[0045] Furthermore, the shape and size of the tablets to be produced are not particularly limited and can be appropriately selected depending on the purpose.

[0046] <2. Application of the oral composition of the present invention> The oral composition of the present invention may be used as it is, or may be used in combination with other foods that do not impair the effects of the present invention. Other foods will be appropriately determined taking into consideration the usage form (functional food) described below.

[0047] The oral composition of the present invention can be easily taken over a long period of time by mixing it with various foods and beverages so that it can be easily taken orally on a daily basis.

[0048] The oral composition containing the above-mentioned components includes not only general foods, but also foods and / or beverages taken for the purpose of maintaining or improving health, such as foods for special dietary uses, foods for specified health uses, foods with functional claims, foods with nutrient functions, dietary supplements, health supplements, supplements, etc. Among these, foods with functional claims that are health functional foods are preferred embodiments. Foods with functional claims include foods that display one or more functions or effects selected from the group consisting of improvement of joint pain, improvement of lower back pain, reduction of physical fatigue, and reduction of neutral fats.

[0049] The form of the oral composition of the present invention is not particularly limited, and may be any form such as solid, liquid, paste (semi-solid), gel, or sol.

[0050] When the oral composition of the present invention is manufactured, various additives used in foods and beverages may be added, specifically, colorants, preservatives, thickening stabilizers, antioxidants, bleaching agents, antibacterial and antifungal agents, acidulants, seasonings, emulsifiers, strengthening agents, manufacturing agents, fragrances, etc.

[0051] The food and drink to which the oral composition of the present invention is applied is not particularly limited. For example, the food includes bread, confectionery, seasoning, retort pouch food, etc. In addition, the beverage includes soft drinks, nutritional drinks, etc.

[0052] The oral composition of the present invention can also be used in the form of a supplement. Examples of the form of the supplement include tablets, powders, powders, granules, capsules, sugar-coated tablets, films, lozenges, jellies, chewable tablets, solutions, emulsions, suspensions, etc. Among these, tablets are preferred.

[0053] When the supplement is in the form of a tablet, the hardness is, for example, 50N or more. If the hardness is low, the tablet is likely to crack or chip, and the tablet's shape retention is poor. In addition, the disintegration time is, for example, within 120 minutes. If the disintegration time is long, it becomes difficult for the tablet to disintegrate quickly in the body. In this specification, the term "hardness" refers to the tablet hardness measured by a hardness tester as shown in the Examples described later, and the term "disintegration time" refers to the time measured by the method described in Section "6.09 Disintegration Test" of the Japanese Pharmacopoeia, 18th Edition as shown in the Examples described later.

[0054] By ensuring that the hardness and disintegration time are within the above ranges, the tablet can be disintegrated in the body when ingested, and at the same time, the tablet can have an appropriate hardness.

[0055] In addition, the supplement may contain any ingredient that is usually used as a supplement, other than the oral composition of the present invention. Such ingredients include, for example, amino acids, peptides, vitamins such as vitamin E, vitamin C, vitamin A, vitamin B, and folic acid, minerals, sugars, inorganic salts, citric acid or its salts, tea extract, oils and fats, tonic ingredients such as propolis, royal jelly, and taurine, herbal extracts such as ginger extract and ginseng extract, and herbs such as collagen.

[0056] When the oral composition of the present invention is used as a health food, the product may display the action or efficacy brought about by the components (functional components) contained in the oral composition of the present invention. For example, the product may be displayed on the body, packaging, container, packaging, or other storage items of the product of the present invention, or on its advertisements. EXAMPLES

[0057] The present invention will be described in more detail below with reference to examples, but the present invention is not limited to these examples.

[0058] The components used in the test examples are as follows: Ingredients (A) and (C): (mixed powder of tamarind seed extract and turmeric extract): Octroll Corporation (TamaFlex (registered trademark)) TamaFlex contains 65% tamarind seed extract and 2.5% turmeric extract. Ingredient (B) (Pomegranate extract): Ikeda Tohka Co., Ltd. (Pomegranate extract powder 10GA) Ingredient (D) (Moringa extract): Taiyo Kagaku Co., Ltd. (Moringa Extract S)

[0059] [Test Example 1: Evaluation of tablet hardness and disintegration time depending on the blend ratio] In order to confirm the change in tablet hardness and disintegration time due to differences in the blending ratio of component (A) and component (B), tablets with different blending ratios of component (A) and component (B) were manufactured and comparative evaluations were performed.

[0060] First, the components were mixed according to the amounts shown in Table 1 below to prepare a composition. Thereafter, the prepared composition was tableted using a hand press (tabletting pressure: 1.0 t) to produce tablets of Examples 1-1 to 1-3 and Comparative Example 1 having the shape shown in FIG. Each tablet had a diameter (D in FIG. 1) of 9 mm and a thickness (H in FIG. 1) of about 4.8 mm, and the total weight of each tablet produced was 330 mg. In addition, other components 1 in Table 1 include celluloses and fine silica dioxide.

[0061] [Table 1]

[0062] The tablets obtained by the above-mentioned methods in Examples 1-1 to 1-3 and Comparative Example 1 were measured for hardness and disintegration time by the following methods. The measurement results are shown in Table 2.

[0063] (Hardness measurement) The hardness (N) of each of the tablets of Examples 1-1 to 1-3 and Comparative Example 1 was measured using a hardness tester.

[0064] (Measurement of disintegration time) The disintegration time of each of the tablets of Examples 1-1 to 1-3 and Comparative Example 1 was measured according to the method described in Section "6.09 Disintegration Test" of the 18th Edition of the Japanese Pharmacopoeia.

[0065] Each tablet of Examples 1-1 to 1-3 or Comparative Example 1 was placed in a disintegration tester (with auxiliary plate) (Toyama Sangyo Co., Ltd., NT-600), and the disintegration state of the tablet was observed. The "disintegration time" was defined as the time from the start of measurement using the disintegration tester until the tablet used in the measurement disintegrated, and these times were measured. The tablet was deemed to have disintegrated when no tablet residue was found, or when any residue was found but was a soft substance that clearly did not retain its original shape.

[0066] [Table 2]

[0067] As shown in Table 2, the tablet of Comparative Example 1 not containing component (B) had low tablet hardness and did not disintegrate even after 300 minutes, whereas the tablets of Examples 1-1 to 1-3 containing component (B) were all confirmed to disintegrate within 300. In particular, the tablet of Example 1-3 had improved tablet hardness and a significantly shortened disintegration time to 70 minutes.

[0068] [Test Example 2: Evaluation of tablet hardness and disintegration time with and without ingredient (B) (pomegranate extract)] In order to confirm the change in tablet hardness and disintegration time due to the presence or absence of component (B), a comparative evaluation was carried out between a tablet containing component (B) (Example 2) and a tablet not containing component (B) (Comparative Example 2).

[0069] Tablets of Example 2 and Comparative Example 2 were manufactured according to the blending amounts shown in Table 3 below. The tablets were produced in the same manner as in the above-mentioned [Test Example 1]. In addition, other ingredients 2 in Table 3 includes excipients in addition to celluloses and fine silicon dioxide.

[0070] [Table 3]

[0071] The hardness and disintegration time were measured for the tablets obtained by the above-mentioned methods in Example 2 and Comparative Example 2. The measurement results are shown in Table 4. The hardness and disintegration time were measured in the same manner as in Test Example 1. The measurement results are shown in Table 4. In addition, in the measurement results in Table 4, the disintegration time of the tablets in Example 2 is the average value of 8 tablets, and the disintegration time of the tablets in Comparative Example 2 is the average value of 3 tablets.

[0072] [Table 4]

[0073] As shown in Table 4, it was confirmed that the tablet of Example 2 containing component (B) had a shorter disintegration time than the tablet of Comparative Example 2 not containing component (B). [Industrial Applicability]

[0074] The oral composition of the present invention is easy to handle and can be easily tableted, and therefore can be easily ingested. In addition, the oral composition of the present invention can be suitably used in functional foods, supplements, etc.

Claims

1. An oral composition comprising (A) a tamarind seed extract and (B) a pomegranate extract.

2. The oral composition according to claim 1, further comprising a turmeric extract (C) and / or a moringa extract (D).

3. 3. The oral composition according to claim 1 or 2, which is a tablet.

4. The oral composition according to claim 3, which is a food with functional claims.

5. mixing a tamarind seed extract (A) with a pomegranate extract (B) to obtain a mixture; compressing the mixture into tablets; A method for producing an oral composition comprising the steps of:

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