Pump and medical device

Abstract

To detect, in an early stage, an anomaly related to the delivery of a chemical liquid.SOLUTION: A syringe pump 100 includes: a barrel 20 that stores a chemical liquid; a pressure sensor 140; and a processor 151. The processor 151 detects an anomaly, based on a pressure measured by the pressure sensor 140 and an amount of change per unit time in the pressure measured by the pressure sensor 140.SELECTED DRAWING: Figure 9

Description

Technical Field

[0001] The present disclosure relates to a pump and a medical device including the pump.

Background Art

[0002] As devices for administering a chemical solution to a patient, pumps such as a syringe pump and an infusion pump are known. For example, a syringe pump delivers a chemical solution in a syringe by moving a plunger rod in a direction (feeding direction) of being pushed into the barrel by a slider.

[0003] In such a pump, the flow path may be blocked due to an influence such as the tube being bent during the delivery of the chemical solution. Japanese Patent Application Laid-Open No. 2009-219637 (Patent Document 1) discloses a technique for determining a blocked state and relieving the pressure in the blocked state.

Prior Art Documents

Patent Documents

[0004]

Patent Document 1

Summary of the Invention

Problems to be Solved by the Invention

[0005] The syringe pump described in Japanese Patent Application Laid-Open No. 2009-219637 (Patent Document 1) determines a blocked state by comparing the internal pressure in the syringe during liquid delivery with a preset blocked setting pressure. Further, the syringe pump described in Japanese Patent Application Laid-Open No. 2009-219637 (Patent Document 1) records the internal pressure in the syringe at predetermined second intervals and warns of the possibility of a blocked state by comparing it with a table in which the blocked setting pressure is recorded.

[0006] However, the syringe pump described in Japanese Patent Application Laid-Open No. 2009-219637 (Patent Document 1) cannot detect an abnormality such as an occlusion state related to the delivery of the chemical solution until the internal pressure of the syringe exceeds the occlusion set pressure in order to determine whether the internal pressure of the syringe during liquid delivery exceeds the occlusion set pressure, and it may take time to detect the abnormality.

[0007] The present disclosure has been made in view of the above problems, and an object thereof is to provide a pump and a medical device capable of detecting an abnormality related to the delivery of a chemical solution at an early stage.

Means for Solving the Problems

[0008] The present disclosure relates to a pump for delivering a chemical solution. The pump includes a container for storing the chemical solution, a pressure sensor for measuring the pressure applied to the container when delivering the chemical solution from the container, and a detection device for detecting an abnormality related to the delivery of the chemical solution from the container. The detection device detects an abnormality based on the pressure measured by the pressure sensor and the amount of change per unit time of the pressure measured by the pressure sensor.

Effects of the Invention

[0009] According to the present disclosure, since an abnormality of the pump is detected based on two parameters, namely, the pressure applied to the container measured by the pressure sensor and the amount of change per unit time of the pressure, the time required to detect an abnormality can be shortened as compared with the case of detecting an abnormality based only on the pressure applied to the container in consideration of the amount of change per unit time of the pressure.

Brief Description of the Drawings

[0010]

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

Figure 7

Figure 8

Figure 9

Figure 10

Embodiments for Carrying Out the Invention

[0011] Hereinafter, embodiments of the present disclosure will be described with reference to the drawings. In the following description, the same members are denoted by the same reference numerals. Their names and functions are also the same. Therefore, detailed descriptions thereof will not be repeated. Further, in the embodiments described below, when referring to the number, amount, etc., unless otherwise specified, the scope of the present invention is not necessarily limited to the number, amount, etc.

[0012] FIG. 1 is a diagram showing the usage state of a blood purification device 1 as an example of a medical device. As shown in FIG. 1, the blood purification device 1 includes a syringe pump 100. The chemical solution sent out from the syringe pump 100 is sent to the patient 2 through a tube. Note that the blood purification device 1 is also referred to as a dialysis device.

[0013] FIG. 2 is a perspective view showing the external appearance of each of the syringe pump 100 and the syringe 10 attached to the syringe pump 100. FIG. 3 is a view taken along the line III in FIG. 2. FIG. 4 is a view taken along the line IV in FIG. 2.

[0014] As shown in FIG. 2, a syringe 10 is attached to the syringe pump 100. The syringe 10 includes a barrel 20 and a plunger rod 30.

[0015] The barrel 20 is a container having a substantially cylindrical outer shape. A liquid injection port 22 is provided at the tip of the barrel 20. A first flange 21 is provided at the rear end of the barrel 20. The barrel 20 is made of a transparent or translucent resin such as polypropylene. The inside of the barrel 20 is filled with a chemical solution.

[0016] The plunger rod 30 is fitted inside the barrel 20 and has a second flange 31 at the rear end. A gasket portion 32 that is in sliding contact with the inner peripheral surface of the barrel 20 is provided on the tip side of the plunger rod 30.

[0017] The syringe pump 100 is configured to start when displacement of elements (clamp 112 and slider 120, described later) that hold the syringe is detected for attachment and detachment of the syringe 10. Thereby, a medical worker (hereinafter also referred to as "user") can start the syringe pump 100 by displacing the above elements when trying to attach the syringe in a state where the syringe pump 100 is not started. Note that activation associated with detection of displacement is not essential. Hereinafter, the configuration of the syringe pump 100 will be described in detail.

[0018] As shown in FIGS. 2 to 4, the syringe pump 100 includes an operation panel 180. The operation panel 180 is provided with various switches including a start switch 183, and displays 181 and 182. In one implementation example, information on the chemical solution filled in the syringe 10 is displayed on the display 181, and information (such as flow rate) regarding the liquid feeding of the chemical solution filled in the syringe 10 is displayed on the display 182. However, the information displayed on the displays 181 and 182 is not limited to these. The displays 181 and 182 may be provided with a touch panel. In this case, the user can input information to the syringe pump 100 by performing a touch operation on the touch panel.

[0019] The syringe pump 100 includes a barrel receiver 110, a boot 117, and a slider 120.

[0020] The barrel receiving portion 110 has a barrel 20 placed thereon. The barrel receiving portion 110 has a concave portion that contacts the lower portion of the outer peripheral surface of the barrel 20. At the rear end of the barrel receiving portion 110, a flange holding portion 115 for holding the first flange 21 is provided. The flange holding portion 115 has a groove portion 111 and a pressing plate 119.

[0021] The pressing plate 119 is inserted into the groove portion 111. A member (not shown) for biasing the pressing plate 119 in the leftward direction (negative X-axis direction) in FIG. 3 is disposed in the groove portion 111. A hall element 131 is provided on the main body of the barrel receiving portion 110, and a magnet 132 is embedded in the pressing plate 119. The first flange 21 is inserted between the hall element 131 and the magnet 132 (pressing plate 119).

[0022] The slider 120 is movable relative to the barrel receiving portion 110. By moving the slider 120, the distance between the barrel receiving portion 110 and the slider 120 is changed. Hereinafter, the direction in which the slider 120 pushes the plunger rod 30 of the syringe 10 into the barrel 20 of the syringe 10 (negative X-axis direction) is referred to as the "feeding direction". Also, the direction opposite to the feeding direction (positive X-axis direction) is also referred to as the "reverse direction".

[0023] The slider 120 is composed of a combination of a plurality of parts. Such a slider 120 is also referred to as a "slider assembly". Specifically, the slider 120 has a slider cover 121, a pressing surface 122 for pressing the second flange 31, and a movable claw portion 123 for sandwiching and holding the second flange 31 between the pressing surface 122.

[0024] The movable claw portion 123 is biased in a direction approaching the pressing surface 122 by a biasing mechanism such as a spring. The slider 120 holds the plunger rod 30 movably toward the barrel 20. Note that the double arrows D1 represent the moving direction of the slider 120. When the plunger rod 30 is moved toward the barrel 20 by the slider 120, the chemical solution in the barrel 20 is injected into the tube from the liquid injection port 22. The arrow D3 in FIG. 2 represents the direction in which the slider 120 moves away from the barrel receiving portion 110 (i.e., the reverse direction) among the directions indicated by the double arrows D1.

[0025] The syringe pump 100 further includes a pressing sensor 140. The pressing sensor 140 is an example of a pressure sensor that measures pressure. The pressing sensor 140 detects the presence or absence of pressing by a member such as the second flange 31 on the pressing surface 122.

[0026] The slider 120 further has a clutch lever 124 for manually adjusting the position of the slider 120 itself and the position of the movable claw portion 123 in the extending direction of the plunger rod 30 when attaching and detaching the plunger rod 30. Specifically, by rotating the clutch lever 124 in one direction, the slider 120 is in a locked state where its manual movement is restricted, and the movable claw portion 123 is maintained in a state biased toward the pressing surface 122. By rotating the clutch lever 124 in the other direction, the slider 120 is in an unlocked state, and the movable claw portion 123 is moved away from the pressing surface 122 against the biasing force.

[0027] Note that the configuration of the slider 120 is not limited to the above, and the slider 120 may have a pressing surface 122 that presses the second flange 31 and a fixed claw portion that accommodates the second flange 31 between the pressing surface 122.

[0028] The syringe pump 100 includes a clamp 112 above the barrel receiving portion 110. The clamp 112 can rotate in the direction of both arrows R0 and can expand and contract in the vertical direction (both arrows D2 direction, Z-axis direction). The clamp 112 includes a telescopic portion 112A and blade portions 112X.

[0029] FIG. 5 is a diagram showing the hardware configuration of the syringe pump 100. As shown in FIG. 5, the syringe pump 100 includes a control unit 150 that controls the operation of the syringe pump 100. The control unit 150 includes a processor 151 that executes a given program and a memory 152 that stores the program executed by the processor 151 and various data necessary for the execution of the program.

[0030] In the syringe pump 100, the operations described in this embodiment are realized by the processor 151 executing a given program. The processor 151 is a computing entity (computer) that executes various processes by executing various programs. The processor 151 is composed of, for example, a processor such as a CPU (Central Processing Unit), MPU (Micro Processing Unit), TPU (Tensor Processing Unit), or GPU (Graphics Processing Unit). Note that although the processor 151 has the function of executing various processes by executing a program, some or all of these functions may be implemented using a dedicated hardware circuit such as an ASIC (Application Specific Integrated Circuit) or FPGA (Field Programmable Gate Array). The "processor" is not limited to a narrow sense processor that executes processing in a stored program manner such as a CPU, MPU, TPU, or GPU, and may include a hardwired circuit such as an ASIC or FPGA. Further, the processor 151 is not limited to a Neumann type computer such as a CPU or GPU, and may be composed of a non-Neumann type computer such as a quantum computer or an optical computer. The processor 151 as described above can also be read as a processing circuitry that executes a predetermined process. Note that the processor 151 may be composed of one chip or a plurality of chips. Furthermore, the processor and related processing circuits may be composed of a plurality of computers interconnected by wire or wirelessly via a local area network or a wireless network or the like. The processor and related processing circuits may be composed of a cloud computer that remotely performs calculations based on input data and outputs the calculation results to other devices located at a remote position.

[0031] The syringe pump 100 includes an interface 101 for communicating with an external device. The communication may be wired communication, in which case the interface 101 may be a USB (Universal Serial Bus) interface. The communication may also be wireless communication, in which case the interface 101 may be a network card. The communication method is not particularly limited.

[0032] The syringe pump 100 includes potentiometers 114 and 170. The potentiometer 114 outputs a voltage value corresponding to the position of the clamp 112 (blade part 112X) in the direction of both arrows D2. The potentiometer 170 outputs a voltage value corresponding to the position of the slider 120 in the direction of both arrows D1. Both the potentiometers 114 and 170 output voltage values to the control unit 150. Here, the method of using the detection outputs of the potentiometers 114 and 170 will be described.

[0033] The processor 151 of the control unit 150 specifies the position of the slider 120 in the direction of both arrows D1 (X-axis direction) based on the voltage value from the potentiometer 170.

[0034] When the plunger rod 30 is set on the slider 120, the position of the plunger rod 30 changes according to the position of the slider 120. The memory 152 may store the remaining amount of the chemical solution in the syringe according to the combination of the size of the syringe and the voltage value (the position of the plunger rod 30), and the processor 151 may output the remaining amount of the chemical solution according to the voltage value from the potentiometer 170.

[0035] The processor 151 identifies the position of the clamp 112 in the direction of both arrows D2 based on the voltage value from the potentiometer 114. The memory 152 may store voltage values corresponding to the size of the syringe, and the processor 151 may output the size of the syringe (e.g., a 10 mL syringe, a 20 mL syringe, etc.) corresponding to the voltage value from the potentiometer 170. In one implementation example, after the user sets the barrel 20 of the syringe 10 in the barrel receiving portion 110, the user lowers the clamp 112 (specifically, the blade portion 112X) to a position where it abuts against the barrel 20. As a result, the position of the clamp 112 (specifically, the blade portion 112X) in the direction of both arrows D2 changes according to the diameter of the barrel 20, and thus changes according to the size of the barrel 20.

[0036] The syringe pump 100 includes a force sensor 142. The force sensor 142 detects the magnitude of the force applied to the slider 120 in the direction of arrow D3 in FIG. 2 and outputs it to the control unit 150. The Hall element 131 also outputs each detection result to the control unit 150.

[0037] The syringe pump 100 includes a motor 194. The motor 194 is typically a stepping motor. The control unit 150 drives the motor 194 to move the slider 120 in the direction of both arrows D1 (X-axis direction).

[0038] The syringe pump 100 includes a rotary encoder 195. The rotary encoder 195 detects the amount of rotation of the motor 194 and outputs it to the control unit 150.

[0039] The notification unit 190 executes a predetermined notification (e.g., voice notification, notification by light emission, etc.) according to a command from the control unit 150. The notification from the notification unit 190 may be a notification other than voice and light emission, or may be a combination of two or more.

[0040] The operation panel 180 is connected to the control unit 150. Signals corresponding to operations on various switches within the operation panel 180, including the start switch 183, are input to the processor 151. The processor 151 controls the displays of the displays 181 and 182.

[0041] Each of the displacement detection sensors 160, 911, 912, and 921 is connected to the control unit 150. The processor 151 acquires the detection outputs from each of the displacement detection sensors 160, 911, 912, and 921. The displacement detection sensor 160 is a sensor for detecting the state (locked / unlocked) of the clutch lever 124. The displacement detection sensors 911 and 912 are sensors for detecting the displacement of the clamp 112. The displacement detection sensor 921 is a sensor for detecting the displacement of the slider 120.

[0042] The syringe pump 100 includes a pressure sensor 140. The pressure sensor 140 is a sensor that measures the pressure applied to the barrel 20 when delivering the chemical solution from the barrel 20, which is a container. The pressure applied to the barrel 20 is detected as the pressure by the member of the second flange 31 on the pressing surface 122.

[0043] Here, the control unit 150 functions as a detection device for detecting an abnormality related to the delivery of the chemical solution from the barrel 20. The processor 151 detects an abnormality based on, for example, the pressure measured by the pressure sensor 140 and the change amount of the pressure measured by the pressure sensor 140 per unit time. The syringe pump 100 of the present embodiment detects an abnormality of the syringe pump 100 based on two parameters, namely, the pressure applied to the barrel 20 measured by the pressure sensor 140 and the change amount of the pressure per unit time. Therefore, considering the change amount of the pressure per unit time, the time required for detecting an abnormality can be shortened compared to the case of detecting an abnormality based only on the pressure applied to the barrel 20. The detection of the abnormality executed by the control unit 150 will be specifically described below.

[0044] FIG. 6 is a diagram showing a correction constant and a determination threshold value. FIG. 6(A) shows the relationship between the amount of chemical solution accommodated in the barrel 20 (the values in the left column of FIG. 6(A)) and the correction constant corresponding to the amount of chemical solution (the values in the right column of FIG. 6(B)). The correction constant is a value corresponding to the sliding resistance generated between the barrel 20 and the gasket portion 32 that is in sliding contact with the inner peripheral surface of the barrel 20. The sliding resistance varies depending on the cross-sectional area of the barrel 20, but the correction constant is obtained in advance considering the cross-sectional area. Hereinafter, the value obtained by adding the correction constant to the value (AD (Analog Data) value) obtained from the pressure sensor 140 is also referred to as the "corrected AD value" or simply the "corrected value". When the value obtained by adding the correction constant to the AD value becomes negative, the corrected AD value is uniformly set to 0.

[0045] FIG. 6(B) shows the three-level (L (Low), M (Middle), H (High)) determination threshold values set for the amount of chemical solution accommodated in the barrel 20 (the values in the leftmost column of FIG. 6(A)). The determination threshold value is a value for comparing with the value obtained by adding the slope, which is the amount of change in pressure per unit time, to the corrected AD value. The determination threshold value is a reference value set in advance through tests and the like, and a plurality of values are stored in the memory 152 together with the correction constant. The processor 151 detects an abnormality in the syringe pump 100 when the added value obtained by adding the corrected AD value and the slope exceeds any one of the determination threshold values.

[0046] Here, since the syringe internal pressure is an absolute value, it takes time to reach the determination threshold value. On the other hand, by considering the amount of change before reaching the determination threshold value, a rapid increase in the syringe internal pressure can also be detected. In the present embodiment, an abnormality determination is made using a new parameter obtained by adding the amount of change to the syringe internal pressure, and both the absolute value and the amount of change of the syringe internal pressure can be considered.

[0047] For example, when using a syringe 10 with a volume of 50 ml, the user sets any one of the L, M, and H values at 50 ml as the determination threshold. When the determination threshold is low, the time until abnormal detection can be shortened compared to when the determination threshold is high, but the number of false determinations increases. On the contrary, when the determination threshold is high, the number of false determinations decreases, but the time until abnormal detection becomes long. Note that even when the determination threshold is high, the time until abnormal detection can be shortened compared to the case where one parameter used for detection (either the corrected AD value or the slope) is used, and the time required for abnormal detection can be shortened.

[0048] Next, an example of abnormal detection by the processor 151 will be described. FIG. 7 is a graph showing the corrected AD value, slope, and corrected AD value + slope in the open state of the tube. FIG. 8 is a graph showing the corrected AD value, slope, and corrected AD value + slope in the blocked state of the tube. FIGS. 7(A) and 8(A) have the cumulative amount of liquid delivery [ml] on the horizontal axis and the corrected AD value [N] on the vertical axis. FIGS. 7(B) and 8(B) have the cumulative amount of liquid delivery [ml] on the horizontal axis and the slope [N / ml] on the vertical axis. FIGS. 7(C) and 8(C) have the cumulative amount of liquid delivery [ml] on the horizontal axis and the corrected AD value + slope on the vertical axis. Here, by setting the horizontal axis as the cumulative amount of liquid delivery, the slope of the graph can be made constant regardless of the amount of liquid delivery compared to the case where the horizontal axis is time.

[0049] In FIGS. 7 and 8, as an example, a syringe 10 with a volume of 50 ml is used, and the graphs are for the case where the flow rate is 5 ml / h and pure water is used as the chemical solution. Here, the slope is based on the corrected AD value, and is obtained as a value with less error using the least squares method for the change amount per unit time of the corrected AD value for the past 10 data. The slope is a value calculated as the change amount per unit time based on the cumulative amount of the chemical solution sent out from the barrel 20 and the pressure measured by the pressing sensor 140.

[0050] As shown in Fig. 7(A), when the tube is in the open state, the corrected AD value increases as the integrated amount increases and then reaches a steady state. As shown in Fig. 7(B), the slope increases once and then decreases after passing the peak. As shown in Fig. 7(C), the corrected AD value + slope increases once and then decreases after passing the peak, similar to the case of the slope.

[0051] As shown in Fig. 8(A), when the tube is in the blocked state, the corrected AD value continues to increase as the integrated amount increases. As shown in Fig. 8(B), the slope increases rapidly at first and then gradually increases as the integrated amount increases. As shown in Fig. 8(C), the corrected AD value + slope increases rapidly at first and then gradually increases as the integrated amount increases. Comparing Fig. 8(B) and Fig. 8(C), the ratio of the increase in the vertical axis with respect to the integrated amount is higher in Fig. 8(C) than in Fig. 8(B). Thus, the time to detect an abnormality can be shortened compared to the determination using only a simple slope.

[0052] The difference between using two parameters, i.e., the corrected AD value and the slope, and using one parameter as in the present disclosure will be described. For example, when only the value of the pressure sensor 140, which is the absolute value of the internal pressure of the syringe, is used, the time required to determine the detection of an abnormality when the flow rate of the chemical solution to be delivered is small becomes extremely long compared to when the flow rate of the chemical solution to be delivered is large. This is because when the flow rate of the chemical solution to be delivered is small, the increase in pressure is gentler compared to when the flow rate of the chemical solution to be delivered is large, so the time to reach the determination threshold value serving as the determination criterion becomes long.

[0053] Next, the case of using only the slope will be considered. According to Hagen - Poiseuille's law, it is known that the longer the tube, the thinner the tube (the smaller the inner diameter of the tube), the higher the viscosity of the chemical solution, and the faster the flow rate, the higher the pressure. In the syringe pump 100, it is difficult to know the length of the connected tube, the inner diameter of the tube, the viscosity of the chemical solution, and the flow rate. Therefore, in the case of conditions where the pressure tends to be high as described above, even if the tube is not in the blocked state, the slope at the initial stage of starting the delivery of the chemical solution becomes large.

[0054] In some cases, the bend of the tube that was bent according to the body movement of Patient 2 may be released. When the bend of the tube is released, the internal pressure of the tube fluctuates greatly. Therefore, if the determination is made using only the inclination, there is a risk of misjudgment at the timing of the pressure fluctuation. For example, there is a risk of misjudgment when the detected pressure detected by the pressing sensor 140 suddenly decreases and then slightly increases. Thus, when only the inclination is used, there is a possibility of misjudgment at the timing when the inclination greatly increases, such as at the initial stage of the start of the delivery of the chemical solution or when the bend of the tube is released.

[0055] On the other hand, the present disclosure can reduce the misjudgment of the occlusion state by using two parameters, the corrected AD value and the inclination, and making a comprehensive determination using these two parameters even when the flow rate is small or the inclination greatly increases. Note that the occlusion state is a concept that includes not only the state where the tube is completely occluded but also the state where a small amount of the chemical solution is being delivered.

[0056] Next, the process executed by the processor 151 will be specifically described. FIG. 9 is a flowchart showing the process executed in the syringe pump 100. The process of the flowchart in FIG. 9 is repeatedly called as a subroutine and executed from the main routine in the control of the processor 151. First, in step S (hereinafter simply referred to as "S") 1, the processor 151 detects the value of the pressing sensor 140.

[0057] Next, the processor 151 determines whether the value of the pressure sensor 140 exceeds a preset upper limit value (S2). The upper limit value is a numerical value for each syringe 10 that is stored in advance in the memory 152. When the processor 151 determines that the value of the pressure sensor 140 exceeds the upper limit value (YES in S2), it stops the pressing operation of the syringe pump 100 (S11). Next, the processor 151 stops the operation of the slider 120 and pulls back the slider 120 in the reverse direction opposite to the feeding direction (S12). Next, the processor 151 sends a command to output a blockage alarm to the notification unit 190 (S13) and returns the process from the subroutine to the main routine.

[0058] In S2, when the processor 151 determines that the value of the pressure sensor 140 does not exceed the upper limit value (NO in S2), it adds a correction constant corresponding to the capacity of the syringe 10 as shown in FIG. 6(A) to the AD value (S3). When the value obtained by adding the correction constant to the AD value becomes negative, the processor 151 calculates the value as 0. The value obtained by S3 is the corrected AD value. Next, the processor 151 calculates the slope as the amount of change per unit time by using the past 10 data of the corrected AD value and the least squares method (S4).

[0059] Next, the processor 151 calculates the value obtained by adding the slope to the corrected AD value (S5). Next, the processor 151 determines whether the value obtained by adding the slope to the corrected AD value exceeds a determination threshold value as shown in FIG. 6(B) (S6). The determination threshold value corresponds to the capacity of the syringe 10 and is one of the values of L, M, and H set by the user.

[0060] In S6, when the processor 151 determines that the value obtained by adding the slope to the corrected AD value does not exceed the determination threshold (NO in S6), the processor 151 returns the process from the subroutine to the main routine. In S6, when the processor 151 determines that the value obtained by adding the slope to the corrected AD value exceeds the determination threshold (YES in S6), the processor 151 sends a command to output an alarm for predicting occlusion to the notification unit 190 (S7). Here, the alarm for predicting occlusion is an alarm indicating the possibility that the tube is in an occluded state, and is a less conspicuous mode compared to the occlusion alarm in S13. The less conspicuous mode is, for example, to notify only by either voice or light emission, or to make the alarm at the time of predicting occlusion smaller than the alarms at the time of voice and light emission. Note that when the processor 151 determines that the value obtained by adding the slope to the corrected AD value exceeds the determination threshold, unlike the process in S12, the processor 151 does not execute the process of stopping the slider 120 and pulling it back in the reverse direction.

[0061] Next, the processor 151 determines whether or not the value obtained by adding the slope to the corrected AD value has become equal to or less than the determination threshold (S8). In S8, when the processor 151 determines that the value obtained by adding the slope to the corrected AD value has not become equal to or less than the determination threshold (NO in S8), the processor 151 returns the process from the subroutine to the main routine. In S8, when the processor 151 determines that the value obtained by adding the slope to the corrected AD value has become equal to or less than the determination threshold (YES in S8), the processor 151 ends the alarm for predicting occlusion, (S9), and returns the process from the subroutine to the main routine.

[0062] As shown in FIG. 9, the processor 151 executes determination for detecting an abnormality of the syringe pump 100 based on two parameters, namely, the corrected AD value and the slope. As a result, the time required for detecting an abnormality can be shortened compared to the case of using one parameter, and false determination in detection can be reduced.

[0063] As shown in S7 and S13 of FIG. 9, when the abnormality of the syringe pump 100 is detected by the pressure sensor 140, the notification unit 190 notifies the occurrence of the abnormality. The notification of the occurrence of the abnormality is in different modes when the upper limit value is exceeded and when the determination threshold value is exceeded. Accordingly, the processor 151 can execute appropriate notification corresponding to the abnormal state.

[0064] FIG. 10 is a diagram showing a rack system 3. The rack system 3 includes a terminal device (information processing device) 60, a plurality of infusion pumps 200A and 200B, and a plurality of syringe pumps 100A, 100B, and 100C. The rack system 3 is operated by a nurse 4 or a doctor. The terminal device (information processing device) 60 is a device for inputting information regarding the chemical solution delivered by each pump. The nurse 4 or the doctor inputs information regarding the chemical solution by performing a touch operation on a touch panel provided in the terminal device.

[0065] Syringes 10 are set in the syringe pumps 100A, 100B, and 100C. Each of the infusion pumps 200A and 200B and the syringe pumps 100A, 100B, and 100C has a display. The infusion pumps 200A and 200B and the syringe pumps 100A, 100B, and 100C are medical pumps used as medical devices. The processing in the detection of the abnormality of the present disclosure may be applied to medical pumps other than the syringe pump 100 such as the infusion pumps 200A and 200B.

[0066] <Aspect> (1) The present disclosure relates to a pump for delivering a chemical solution. The pump includes a container for storing the chemical solution, a pressure sensor for measuring the pressure applied to the container when delivering the chemical solution from the container, and a detection device for detecting an abnormality related to the delivery of the chemical solution from the container. The detection device detects an abnormality based on the pressure measured by the pressure sensor and the change amount per unit time of the pressure measured by the pressure sensor.

[0067] According to the pump of the present disclosure, in order to detect an abnormality of the pump based on two parameters of pressure and the amount of change in pressure per unit time, it is possible to shorten the time required for detecting an abnormality compared to using one value.

[0068] (2) The pump according to (1), wherein the detection device detects an abnormality based on a corrected value calculated by correcting the pressure measured by the pressure sensor and the amount of change in pressure per unit time.

[0069] According to the pump of the present disclosure, in order to detect an abnormality of the pump based on two parameters of a corrected value calculated by correcting the pressure and the amount of change in pressure per unit time, it is possible to shorten the time required for detecting an abnormality compared to using one value.

[0070] (3) The pump according to (2), wherein the detection device determines whether an added value obtained by adding the corrected value and the amount of change in pressure per unit time exceeds at least one threshold value, and detects an abnormality when the added value exceeds at least one threshold value.

[0071] According to the pump of the present disclosure, the detection device determines whether an added value obtained by adding the corrected value and the amount of change in pressure per unit time exceeds at least one threshold value, and can perform a determination suitable for the threshold value in order to detect an abnormality when the added value exceeds at least one threshold value.

[0072] (4) The pump according to any one of (1) to (3), wherein the detection device calculates the amount of change per unit time based on the integrated amount of the chemical solution sent out from the container and the pressure measured by the pressure sensor.

[0073] According to the pump of the present disclosure, the detection device can calculate the amount of change per unit time based on the integrated amount of the chemical solution sent out from the container and the pressure measured by the pressure sensor, so that the same slope can be obtained regardless of the amount of liquid delivery.

[0074] (5) The pump according to any one of (1) to (4), wherein the abnormality includes that the container is in a blocked state.

[0075] According to the pump of the present disclosure, it is possible to suitably detect whether the container is in a blocked state based on two parameters.

[0076] (6) The pump according to (3), wherein at least one threshold value includes a plurality of threshold values having different values from each other according to the degree of abnormality.

[0077] According to the pump of the present disclosure, it is possible to execute a determination suitable for the threshold value by using a plurality of threshold values having different values from each other according to the degree of abnormality.

[0078] (7) The pump according to any one of (1) to (6), further comprising a notification unit that notifies the occurrence of an abnormality when the abnormality is detected by the detection device.

[0079] According to the pump of the present disclosure, when the abnormality is detected by the detection device, it is possible to suitably notify the occurrence of the abnormality by the notification unit.

[0080] (8) The pump according to any one of (2) to (7), wherein the pump is a syringe pump including a plunger rod having a gasket portion slidably contacting the inner peripheral surface of the container attached to its tip. The detection device calculates, as a correction value, a value obtained by subtracting the sliding resistance generated between the inner peripheral surface of the container and the gasket portion from the pressure measured by the pressure sensor.

[0081] According to the syringe pump of the present disclosure, since a value obtained by subtracting the sliding resistance generated between the inner peripheral surface of the container and the gasket portion from the pressure measured by the pressure sensor is calculated as a correction value, it is possible to suitably detect an abnormality considering the sliding resistance.

[0082] (9) The medical device of the present disclosure includes the pump according to any one of (1) to (8) and a terminal device for inputting information regarding the chemical solution delivered by the pump.

[0083] According to the medical device of the present disclosure, an abnormality can be detected by appropriately using information on the chemical solution by a terminal device for inputting information on the chemical solution delivered by a pump.

[0084] <Modification example> In the above, the horizontal axis was the integrated amount in FIGS. 7 and 8. However, a graph with the horizontal axis as time may also be used.

[0085] In the process of FIG. 9, the processor 151 may apply a multivariate analysis model using the corrected AD value and the slope as explanatory variables and execute determination of the occlusion state.

[0086] In the process of FIG. 9, the processor 151 may calculate respective regression variables using the corrected AD value and the slope as explanatory variables, apply a logistic analysis model to the multivariate analysis model, and execute determination of the occlusion state.

[0087] The embodiments disclosed this time should be considered to be illustrative in all respects and not restrictive. The scope of the present disclosure is indicated by the claims, and it is intended that all modifications within the meaning and scope equivalent to the claims be included.

Description of reference signs

[0088] 1 Blood purification device, 2 Patient, 3 Rack system, 4 Nurse, 10 Syringe, 20 Barrel, 21 First flange, 22 Liquid injection port, 30 Plunger rod, 31 Second flange, 32 Gasket part, 100, 100A, 100B, 100C Syringe pump, 101 Interface, 110 Barrel receiving part, 111 Groove part, 112 Clamp, 112A Telescopic part, 112X Blade part, 114, 170 Potentiometer, 115 Flange holding part, 117 Boot, 119 Pressing plate, 120 Slider, 121 Slider cover, 122 Pressing surface, 123 Movable claw part, 124 Clutch lever, 131 Hall element, 132 Magnet, 140 Pressure sensor, 142 Force sensor, 150 Control unit, 151 Processor, 152 Memory, 160, 911, 912, 921 Displacement detection sensor, 180 Operation panel, 181, 182 Display, 183 Start switch, 190 Notification part, 194 Motor, 195 Rotary encoder, 200A, 200B Infusion pump.

Claims

1. A pump for delivering a chemical solution, comprising a container for containing the chemical solution, a pressure sensor for measuring the pressure applied to the container when delivering the chemical solution from the container, and a detection device for detecting an abnormality related to the delivery of the chemical solution from the container, wherein the detection device detects the abnormality based on the pressure measured by the pressure sensor and the change amount per unit time of the pressure measured by the pressure sensor.

2. The pump according to claim 1, wherein the detection device detects the abnormality based on a corrected value calculated by correcting the pressure measured by the pressure sensor and the change amount per unit time of the pressure.

3. The detection device, determines whether an added value obtained by adding the corrected value and the change amount per unit time of the pressure exceeds at least one threshold value, and detects the abnormality when the added value exceeds the at least one threshold value. The pump according to claim 2.

4. The pump according to any one of claims 1 to 3, wherein the detection device calculates the change amount per unit time based on the integrated amount of the chemical solution delivered from the container and the pressure measured by the pressure sensor.

5. The pump according to any one of claims 1 to 3, wherein the abnormality includes that the container is in a blocked state.

6. The pump according to claim 3, wherein the at least one threshold value includes a plurality of threshold values having different values according to the degree of the abnormality.

7. The pump according to claim 1, further comprising a notification unit for notifying the occurrence of the abnormality when the abnormality is detected by the detection device.

8. The pump is a syringe pump including a plunger rod having a gasket portion slidable on the inner peripheral surface of the container, and The detection device calculates, as the correction value, a value obtained by subtracting a sliding resistance generated between the inner peripheral surface of the container and the gasket portion from the pressure measured by the pressure sensor, according to the pump of claim 2.

9. The pump according to claim 1, and A medical device including a terminal device for inputting information regarding the chemical solution delivered by the pump.

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