Oct data processing device, control method for oct data processing device, and program

Abstract

To efficiently perform alignment between data acquired by a perimeter and data acquired by an OCT imaging device.SOLUTION: There is provided an OCT data processing device that can be connected to a system that acquires visual field measurement data. The OCT data processing device includes output means that outputs first data that can be input to the system. The first data includes: two-dimensional frontal data based on three-dimensional OCT data or three-dimensional OCT motion contrast data of a subject eye; and first information being information indicating the positions of a plurality of specific portions on the image based on the two-dimensional frontal data.SELECTED DRAWING: Figure 3

Description

Technical Field

[0001] The disclosure of this specification relates to an OCT data processing device, a control method for an OCT data processing device, and a program.

Background Art

[0002] In ophthalmology, visual field defects caused by eye diseases such as glaucoma are measured by a visual field meter. On the other hand, it is known that by using an optical coherence tomography (OCT), it is possible to early detect the progression of visual field defects such as glaucoma and signs before visual field defects from the state of thinning of the retinal layer thickness. In addition, it is expected that by using an Angiogram image obtained from a motion contrast image by OCT, signs even earlier than changes in the retinal layer thickness can be detected.

[0003] In Patent Document 1, registration of the fundus frontal images acquired by OCT and the visual field meter respectively is performed to align the OCT En Face image and the visual field map image.

Prior Art Documents

Patent Documents

[0004]

Patent Document 1

Summary of the Invention

Problems to be Solved by the Invention

[0005] However, in Patent Document 1, since registration of the fundus frontal images acquired by OCT and the visual field meter respectively is performed, advanced image processing is required, and it is difficult to efficiently align the acquired OCT data and visual field measurement data.

Means for Solving the Problems

[0006] An OCT data processing device according to an embodiment of the present disclosure is an OCT data processing device connectable to a system that acquires visual field measurement data, wherein the OCT data processing device has output means for outputting first data that can be input to the system, wherein the first data is OCT data processing device including two-dimensional frontal data based on three-dimensional OCT data or three-dimensional OCT motion contrast data of an eye to be examined, and first information indicating positions of a plurality of specific parts on an image based on the two-dimensional frontal data.

[0007] Further, an OCT data processing device according to another embodiment of the present disclosure is an OCT data processing device connectable to a system that acquires visual field measurement data, having acquisition means for acquiring two-dimensional frontal data based on three-dimensional OCT data or three-dimensional OCT motion contrast data of an eye to be examined, and input means for inputting second data output from the system, wherein the second data is OCT data processing device including the visual field measurement data and fourth information that is information capable of specifying at least one position among a plurality of specific parts on an image based on the visual field measurement data.

[0008] Further, a control method for an OCT data processing device according to another embodiment of the present disclosure is a control method for an OCT data processing device connectable to a system that acquires visual field measurement data, the method including a step of the OCT data processing device outputting first data that can be input to the system, wherein the first data is a control method for an OCT data processing device including two-dimensional frontal data based on three-dimensional OCT data or three-dimensional OCT motion contrast data of an eye to be examined, and first information indicating positions of a plurality of specific parts on an image based on the two-dimensional frontal data.

[0009] Also, a control method for an OCT data processing device according to another embodiment of the present disclosure is a control method for an OCT data processing device connectable to a system that acquires visual field measurement data, comprising: a step of acquiring three-dimensional OCT data of an eye to be examined or two-dimensional frontal data based on three-dimensional OCT motion contrast data; a step of inputting second data output from the system, wherein the second data is a control method for an OCT data processing device including the visual field measurement data and fourth information that can identify the positions of a plurality of specific parts on an image based on the visual field measurement data.

Advantages of the Invention

[0010] According to the disclosure of this specification, it becomes possible to efficiently align the data acquired by a perimeter and the data acquired by an OCT imaging device.

Brief Description of the Drawings

[0011]

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Best Mode for Carrying Out the Invention

[0012] Hereinafter, exemplary embodiments for carrying out the present invention will be described in detail with reference to the drawings. However, the dimensions, materials, shapes, relative positions of the components, etc. described in the following embodiments are arbitrary and can be changed according to the configuration of the apparatus to which the present invention is applied or various conditions. Also, in the drawings, the same reference numerals are used between the drawings to indicate the same or functionally similar elements. Also, some of the components, members, and parts of the processing that are not important for the explanation may be omitted from the display in each drawing.

[0013] Note that in this embodiment, although OCT data for glaucoma examination is handled as OCT data, it is not limited thereto. OCT data capable of creating an Angiogram image or OCT data for macular disease examination such as age-related macular degeneration may also be used.

[0014] <Example 1> With reference to FIGS. 1 to 5, the OCT data processing apparatus 100 of this embodiment will be described. The OCT data processing apparatus 100 of this embodiment can be connected to a system that acquires visual field measurement data.

[0015] (Configuration of OCT Data Processing Apparatus) Referring to FIG. 1, the configuration of the OCT data processing apparatus 100 of this embodiment will be described. FIG. 1 schematically shows the configuration of the OCT data processing apparatus 100. The OCT data processing apparatus 100 includes a control means 105, a storage means 102, and an output means 104, has a display means 110 and an operation means 120, and is connected to a perimetry system 130. Further, the control means 105 includes a data acquisition means 101, a display control means 103, a determination means 106, an instruction reception means 107, a display control means 108, an image generation means 109, and a calculation means 111.

[0016] The data acquisition means 101 acquires OCT data and stores it in the storage means 102. As a method for acquiring OCT data, there are a method of controlling an OCT imaging device (not shown) to perform imaging and the data acquisition means 101 acquiring the generated OCT data, and a method of the data acquisition means 101 reading OCT data placed in a storage area outside the OCT data processing apparatus 100 or DICOM format OCT data stored in a PACS or the like. The data acquisition means 101 converts the acquired OCT data into a data format that can be handled by the OCT data processing apparatus 100 and stores it in the storage means 102. At that time, simultaneously, information such as patient-related information, device-related information, and imaging-related information obtained when acquiring the OCT data, and fundus photographs and infrared fundus images linked to the OCT data are also stored together as necessary. Further, when there is no analysis data such as layer boundaries in the acquired OCT data, necessary analysis is performed on the OCT data to obtain analysis data (data of the analysis result), and it is stored together with the acquired OCT data.

[0017] The storage means 102 holds information regarding the eye to be examined (such as the patient's name, age, gender, etc.), information regarding the OCT imaging device used for imaging (such as the model name, type of OCT, etc.), tomographic images, motion contrast images, linked fundus photographs, infrared fundus images, imaging information (left or right eye, imaging size, imaging format, number of scans in the X-axis direction of the OCT · number of scans in the Y-axis direction of the OCT · number of repeated scans at the same position, etc.), imaging alignment parameter information (position of the fixation lamp, imaging position, focus value of the infrared fundus image or OCT, C-Gate position, etc.), and analysis results of the OCT data (layer boundaries, macular center position, optic disc center position, etc.).

[0018] The instruction receiving means 107 receives an operation of selecting specific OCT data from the data stored in the storage means 102 by the operation of the operation means 120, and displays an image related to the selected OCT data, for example, a tomographic image, a fundus photograph, an infrared fundus image, an analysis result, a map image, an En Face image, etc. on the display means 110 in a specific layout format. Further, the instruction receiving means 107 receives an output instruction of data from the operator by the operation of the operation means 120, and the output control means 108 instructs the output means 104 to output the data. Note that the operation means 120 is, for example, a mouse or a keyboard. The display means 110 is, for example, a monitor or a projector. Also, when the display means 110 is a touch panel display or a tablet, etc., the display means 110 and the operation means 120 have an integrated configuration.

[0019] The output means 104 outputs first data including two-dimensional front data based on three-dimensional OCT data or three-dimensional OCT motion contrast data, which is the selected OCT data or data related to the selected OCT data, and information indicating the positions of a plurality of specific parts on the image based on the two-dimensional front data, and the output first data is input to the perimeter system 130. At this time, the output data may be input to the perimeter system 130 after performing partial data deletion or data processing on the output data. Also, the output first data only needs to be inputtable to the perimeter system 130. For example, the OCT data processing device 100 may be configured to directly transmit the first data to the perimeter system 130 using a standard such as FTP or DICOM, or the OCT data processing device 100 may temporarily store the first data in an intermediate system such as a PACS or an electronic medical record to which both the OCT data processing device 100 and the perimeter system 130 can be connected, and the perimeter system 130 may acquire the first data from there via the intermediate system.

[0020] The two-dimensional frontal data based on the three-dimensional OCT data or three-dimensional OCT motion contrast data of the eye to be examined included in the first data may be an image file or data capable of generating an image in the perimeter system 130. Examples of the former include OCT analysis map images such as layer thickness map images and layer thickness comparison map images with a normal eye database, OCT En Face images, OCTA images (OCT frontal motion contrast images), and vessel density map images.

[0021] In addition, the first data includes first information indicating the positions of a plurality of specific sites on the image based on the two-dimensional frontal data. The first information may be information capable of specifying the positions of a plurality of specific sites on the image based on the two-dimensional frontal data (when based on a predetermined position), or information indicating the positions of a plurality of specific sites on the image based on the two-dimensional frontal data. By using the first information, the perimeter system 130 can efficiently align, for example, an image generated from two-dimensional frontal data based on three-dimensional OCT data or three-dimensional OCT motion contrast data with an image based on perimeter measurement data when it is desired to compare the perimeter measurement data with the OCT map image, etc., and display them in correspondence.

[0022] The specific sites described here may be sites within a part having the anatomical features of the eye to be examined. More specifically, the plurality of specific sites are the fovea center and the optic disc center. The first information, which is information indicating the positions of the plurality of specific sites on the image based on the two-dimensional frontal data, may be, for example, the pixel position information (which can also be called coordinate information) of the plurality of specific sites on the image based on the two-dimensional frontal data. Therefore, for example, when the image based on the two-dimensional frontal data is an OCT analysis map image, the first information may be information indicating the positions of the fovea center and the optic disc center on the OCT analysis map image, or may be the coordinate information of the first to plurality of branch points of each major blood vessel starting from the optic disc part at specific feature points of the retinal blood vessels on the OCT analysis map image. Note that the two-dimensional frontal data and information other than the first information that may be included in the first data will be described in step S308 below.

[0023] Note that the perimetry system 130 in this specification may be any system that can acquire perimetry measurement data measured by a perimeter. For example, it may be a device for performing perimetry measurement (i.e., a perimeter), a data processing device that can obtain perimetry measurement data stored in another system through a network connection, or an electronic system that stores perimetry measurement data such as an electronic medical record or a PACS.

[0024] (OCT data display screen of the OCT data processing device) Next, with reference to FIG. 2, the OCT data display screen displayed by the display means 103 of this embodiment will be described. FIG. 2 is a report display screen 200 in which the OCT data specified by the operator from the data stored in the storage means 102 is displayed in a report format along a specific layout.

[0025] On the report display screen 200, the OCT data of the patient specified on a patient screen (not shown) is displayed by the display control means 103, and it is possible to instruct transfer to the perimetry system 130 on the report display screen 200. Hereinafter, an example will be described in which the OCT data of the left and right eyes obtained in the glaucoma examination mode is displayed in an examination data display layout for displaying both eyes.

[0026] The report display screen 200 has an OCT data list display area 210 and a display area 220 for the specified OCT data. In the OCT data list display area 210, only the OCT data of the currently specified patient is extracted from the OCT data stored in the storage means 101, and the outlines of each OCT data are arranged in a list format.

[0027] The OCT data is grouped in units of the examination date and the left and right eyes, and the examinations within the grouping are arranged in the order of the shooting time. At this time, the shooting dates are arranged in descending order and the shooting times are arranged in ascending order. By selecting one OCT data (here 211) from the OCT data displayed in the OCT data list display area 210, the image, related data, shooting information, etc. of the specified OCT data 211 are read from the storage means 102 and displayed in the display area 220 of the specified OCT data.

[0028] The inspection data display layout to be displayed in the designated display area 220 of the OCT data can be specified by the operator from inspection data display layouts for different purposes such as single-inspection display, left / right eye display, and comparison display of past inspections. Images and inspection information corresponding to the specified inspection data display layout are displayed. For example, in the case of a report display for glaucoma inspection, a fundus photograph or fundus infrared image that includes the OCT imaging range is displayed in the fundus frontal image display area 223. Also, a GCC thickness map image that shows the distribution of the thickness of the layer representing the ganglion cell complex (GCC) used in the diagnosis of glaucoma in a color chart is generated from the layer analysis result of the OCT data and displayed in front of the fundus frontal image area 223. The thickness of the GCC is obtained by calculating the thickness from the detection results of three layers, namely the nerve fiber layer (NFL), ganglion cell layer (GCL), and inner plexiform layer (IPL), or two layers, namely the ganglion cell layer and the inner plexiform layer, in the layer analysis result. Further, 222A is a normal eye database map display area, and in 222B, a deviation map and a significance map calculated by comparing the distribution of the thickness of the GCC displayed in the fundus frontal image area 223 using the normal eye database stored in the storage unit 102 are displayed. Next, in the sector display area 224, for a specific area centered on the macula, three types of sector divisions, namely the whole area, upper and lower divided areas, and eight divided areas, are performed, and the average thickness of the GCC in the area within each sector is displayed. Note that the range of the eight divided areas is shown on the GCC thickness map image displayed on the fundus frontal image area 223. Further, as the background color of each sector, a color assigned based on a color chart according to the result of comparison with the normal eye database is displayed.

[0029] Also, when specifying a layout for simultaneously displaying OCT data other than the selected OCT data, such as the left and right eye display layout, other OCT data is also read from the storage means 102 based on the imaging information of the specified OCT data and is displayed together with a fundus frontal image, a map image, etc., in the same manner as the selected OCT data. For example, when the operator specifies the left and right eye display layout, data taken on the same day as the selected OCT data is displayed from among the data taken in the same imaging format and in the same region of the eye opposite in left and right to the eye from which the selected OCT data was acquired. Note that it is also possible for the operator to select the OCT data to be displayed simultaneously.

[0030] In the display area 220 of the selected OCT data, a two-dimensional frontal data output button, which is an operation area, is further displayed. In this embodiment, a map output button 221 is displayed as the two-dimensional frontal data output button. When the operator presses the map output button 221 via the operation means 120, the output means 104 transmits first data to the perimeter system 130. The first data is the data displayed in the display area 220 of the selected OCT data or data related thereto, includes two-dimensional frontal data and first information, and can be used when registering with the perimetry data acquired by the perimeter system and additional information.

[0031] (Flow of map image transfer to the perimeter system according to this embodiment) Next, with reference to FIG. 3, the flow when outputting first data to the perimeter system in the OCT data processing apparatus according to this embodiment will be described. FIG. 3 shows a flowchart according to this embodiment.

[0032] In the following flow, based on the 3D OCT data or 2D frontal data based on the 3D OCT motion contrast data of the eye to be examined, an OCT map image (here, the OCT layer thickness map of GCC (IPL + NFL + GCL or NFL + GCL)) generated based on the 3D OCT data of the eye to be examined is used. As the first information indicating the positions of a plurality of specific parts on the image based on the 2D frontal data, it will be described using the coordinate information of the optic disc center and the fovea center on the GCC layer thickness map image. Here, although the GCC layer thickness map image is used as the image based on the 2D frontal data, an RNFL layer thickness map image, a retinal thickness map image, a choroid thickness map image, etc. may also be used.

[0033] In step S301, the operator uses the operation means 120 to select the examination 211 that has acquired the 2D frontal data to be transmitted from the OCT data list display area 210. In this embodiment, it is assumed that the examination in the examination mode for glaucoma examination is selected.

[0034] In step S302, the display control means 103 reads the OCT data acquired in the examination selected by the operator in step S301 from the storage means 102 and displays it in the display area 220 displayed on the display means 110. In this step, since it is displayed in a layout that displays the OCT data of both the left and right eyes, the display control means 103 also reads the OCT data of the eye opposite to the selected examination 211 (if the selected OCT data 211 is one of the left and right eyes of the subject, the other eye) from the storage means 102 and displays it in the display area 220.

[0035] In step S303, the determination means 106 determines whether the OCT data acquired in the selected examination 211 can be output to the perimetry system 130. For the determination by the determination means 106, it may be used as a determination criterion whether the data acquired in the selected examination 211 is transmissible data, or it may be used as a determination criterion such as whether age, gender, etc., which are conditions for displaying a comparison map with the normal eye database, are included in the patient information. Also, it may be used as a determination criterion whether the perimetry system 130 is set as the transmission destination and whether the perimetry system 130 of the transmission destination is receivable. For example, the determination means 106 can determine whether the OCT data acquired in the selected examination 211 is transmissible data, using as determination criteria the imaging mode at the time of acquiring the OCT data and the type of examination display layout. For example, when the imaging mode is an imaging mode for glaucoma (Glaucoma 3D or Wide 3D) having a report layout in which a GCC layer thickness map is displayed, and the examination data display layout is a monocular or binocular display layout, it is determined that the data is transmissible to the perimetry system 130.

[0036] In step S304, when in step S303 the determination means 106 determines that transmission to the perimetry system 130 is possible, the output control means 108 activates a trigger for outputting an OCT map image, which is two-dimensional front data based on three-dimensional OCT data or three-dimensional OCT motion contrast data, to the perimetry system 130. Here, the display control means 103 displays an OCT map output button 221 in the display area 220 of the selected OCT data. Thereby, in a later step S305, the operator can arbitrarily give an instruction to transmit the OCT map image to the perimetry system 130.

[0037] Next, in step S305, the operator gives a transmission instruction to transmit the OCT map image to the perimetry system 130. Here, when the operator presses the OCT map output button 221 on the display area 220 of the selected OCT data, the output control means 108 instructs the output means 104 to perform a transmission process.

[0038] Next, in step S306, an OCT map image, which is two-dimensional frontal data included in the first data transmitted by the image generation means 109 to the perimeter system, is generated. The generated OCT map image is, for example, an image in which conditions (such as layers) for generating a map are specified on a preset screen or the like, and an image necessary for displaying together with the perimeter result in the perimeter cooperation system is generated. The images generated here are three maps, namely, a GCC layer thickness map, a Significance map, and a Deviation map, and a fundus photograph or an infrared fundus image displayed in the fundus frontal image area 223. At this time, the image generation means 109 generates an image by converting the image using the analysis data of the OCT data or the like from the storage means 102 into a predetermined pixel size. The OCT data is stored with the number of scans in the X-axis direction and the Y-axis direction at the time of imaging. However, in order to facilitate matching with the perimeter measurement result, the image is converted so that the aspect ratio in the XY direction becomes the same. For example, in the case of data obtained by scanning 10 mm in the Y-axis direction with 1024 scans and 10 mm in the X-axis direction with 128 scans centered on the macula, an image of 1024×1024 pixels expanded 8 times in the X-axis direction is generated. Here, although this step has been described as a step for generating an OCT map image, this step may be a step for selecting an OCT map image to be transmitted from a plurality of two-dimensional frontal data obtained or related to the selected examination 211 and generated in advance.

[0039] Next, in step S307, for each of the images to be transmitted to the perimeter system generated in step S306, information indicating the positions of a plurality of specific sites required for alignment with the perimetry data acquired by the perimeter system is calculated. The information indicating the positions described here is information necessary for adjusting the positional relationship with the perimetry data when the two-dimensional frontal data generated in step S306 is received by the perimeter system 130. For example, regarding a plurality of specific sites of the eye under examination for which data is acquired in both the image generated in step S306 and the perimetry data (which can also be said to be parts having anatomical features), it is information indicating the positions on the image generated in step S306. In this embodiment, it is information indicating the coordinates of the pixels corresponding to the fovea center and the optic disc center on the OCT map image. By using the information indicating the positions of the plurality of specific sites required for this alignment, even between different devices and systems (for example, an OCT data processing device and a perimeter system), the positions can be finely aligned including adjustments such as scaling and rotation of the images. The OCT data processing device can identify the positions of the fovea center and the optic disc center (which are positions within parts having anatomical features) from the fixation position, the optical system, the layer analysis of the tomographic image, the information of the fundus frontal image, etc. at the time of imaging, and can calculate the identified positions as the coordinate information of the pixels on the image generated in step S306 and use them as information indicating the positions. Note that the coordinate information may be, for example, information expressing which pixel position in the rightward and downward directions with the position of the upper left pixel on the image based on the two-dimensional frontal data being (1,1). Note that when the specific site is not included in the image for which the coordinate information is calculated, the coordinate information outside the image may be calculated and used.

[0040] Next, after step S307, in step S308, information to be output together with the OCT map image, which is two-dimensional frontal data included in the first data (hereinafter may also be referred to as additional information) is generated. Based on the coordinate information calculated in step S307, first information is generated, which is information indicating the positions of a plurality of specific parts on the OCT map image included in the additional information. Here, the additional information may include second information other than the first information. When the additional information includes the second information, the process proceeds to step S308 to acquire the second information.

[0041] Examples of the second information to be acquired include information regarding the resolution of the OCT map image output by the output means 104, information regarding the size on the fundus based on an image (e.g., an OCT image) acquired by the OCT data processing device, information used when generating a composite image in subsequent steps, such as information regarding the size on the fundus, left and right eye information, patient information, and other information for identifying the eye to be examined, information regarding the imaging mode, information indicating the type of image based on the two-dimensional frontal data, an image acquired by a modality other than OCT associated with the OCT data, information regarding the range in which the image based on the two-dimensional frontal data is generated (e.g., information regarding the depth range or layer in which the image is generated), diagnostic information such as finding information, and information regarding the imaging date and time. Examples of such images include an SLO image, a color fundus image, a fundus camera image, and an OCT En Face image acquired in an examination in which three-dimensional OCT data used for acquiring two-dimensional OCT data was acquired. When the second information includes an image acquired by a modality other than OCT, the second information may include information indicating the positions of a plurality of specific parts on the image acquired by a modality other than OCT, which was acquired in steps S307 and S308, patient information and imaging time when the image acquired by a modality other than OCT was acquired, and other information used when selecting the perimetry data to be superimposed later, and information indicating the type of the image. Thereby, even if the image acquired by a modality other than OCT has a different scale and aspect ratio from the map image and the perimetry data, registration between the image acquired by a modality other than OCT and the map image in the perimetry system 130 becomes possible.

[0042] For example, when the two-dimensional front data to be output is an OCT map image based on the three-dimensional OCT data acquired in the glaucoma examination mode, the second information included in the first data may include analysis data related to glaucoma diagnosis information such as the comparison result with the normal eye database assigned to the upper and lower divided regions displayed in the sector display region 224 within the display region 220 of the selected OCT data, which is acquired from the storage means 102.

[0043] Finally, in step S309, the output means 104 outputs the OCT map image acquired in step S306, the information (first information) indicating the positions of the fovea centralis and the optic disc center on the OCT map image acquired in step S307, and the first data including the second information acquired in step S308 if there is the second information acquired in step S308. The first data is transmitted to, for example, the perimeter system 130 or stored in a storage destination (e.g., a shared folder) connectable to either the OCT data processing apparatus 100 or the perimeter system 130. At this time, for example, by including the information (first information) indicating the positions of the fovea centralis and the optic disc center on the OCT map image calculated in step S307 and the second information acquired in step S308 in the file name of the OCT map image and saving the OCT map image, the first data including the first information and the second information can be saved together with the OCT map image. Thereby, when the perimeter system 130 reads the OCT map image included in the first data output by the output means 104, at the same time, the first information, which is the information indicating the positions of the fovea centralis and the optic disc center on the OCT map image, and the second information such as the diagnosis information can be acquired from, for example, the file name of the OCT map image. In this way, by using the information (additional information) other than the OCT map image included in the first data, on the perimeter system 130 side, the registration between the OCT map image output by the OCT data processing apparatus 100 and the perimetry measurement data can be performed with a lower processing load as compared with the case of using, for example, the alignment of fundus images.

[0044] Here, a method of including the first information and the second information in the file name of the OCT map image has been described. However, a file different from the OCT map image may include these information, and the OCT map image and the said file may be collectively referred to as the first data.

[0045] Also, although the configuration has been described in which the two-dimensional frontal data included in the first data output by the output means 104 is an image file, the two-dimensional frontal data included in the first data does not have to be an image file. For example, it may be a method of outputting a file as a DICOM image and storing additional information (the first information and the second information) in DICOM tags.

[0046] (Alignment of OCT data with an image on the perimetry system according to this embodiment) Next, with reference to FIGS. 4 and 5, a method of aligning an image based on two-dimensional frontal data output from the OCT data processing apparatus 100 and acquired by the perimetry system 130 with an image based on perimetry measurement data will be described. FIG. 4 shows an example of a second composite image 400 generated by superimposing perimetry measurement data 420 on a first composite image that displays a fundus frontal image 411 output from the OCT data processing apparatus 100 and an OCT map image 410 which is two-dimensional frontal data based on three-dimensional OCT data or three-dimensional OCT motion contrast data. Further, FIG. 5 shows a flowchart of composite image generation according to this embodiment.

[0047] In step S501, the perimeter system 130 reads the two-dimensional frontal data included in the first data output from the output means 104. At this time, if there are multiple types of two-dimensional frontal data included in the first data, the two-dimensional frontal data corresponding to the image to be displayed is read. For example, if there are multiple types of two-dimensional frontal data included in the first data, and only the Significance map image is to be displayed among them, then an image corresponding to the Significance map image is read from the two-dimensional frontal data. When simultaneously displaying multiple images based on each of the multiple types of two-dimensional frontal data, all the necessary two-dimensional frontal data may be read. In that case, the processes after step S502 are performed for each type of two-dimensional frontal data.

[0048] In step S502, a determination means (not shown) included in the perimeter system 130 determines whether the first data output from the output means 104 includes a fundus frontal image corresponding to the OCT map image, which is the two-dimensional frontal data read by the perimeter system 130 in S501. If the output first data includes a fundus frontal image (fundus camera image, fundus infrared image, SLO image) corresponding to the read OCT map image, the process proceeds to step S503. In steps S503 to S506, the fundus frontal image and the OCT map image are aligned to generate a first composite image. On the other hand, if the output first data does not include a fundus frontal image corresponding to the read OCT map image, the process proceeds to step S507, and alignment with the perimetry data is performed using only the read OCT map image. In the latter case, if the output first data includes multiple types of two-dimensional frontal data, a composite image of the images based on the two-dimensional frontal data may be generated and the process may proceed to step S507.

[0049] In step S503, the perimeter system 130 reads the fundus frontal image 411 included in the output data output from the output means 104.

[0050] Next, in step S504, among the additional information included in the first data output from the output means 104, the first information including information indicating the positions of a plurality of specific parts on the OCT map image 410 and the information (third information) indicating the positions of a plurality of specific parts on the fundus frontal image shown in 411 are acquired. Here, the coordinate information of the pixels of the fovea center and the optic disc center in each image is acquired.

[0051] Next, in step S505, based on the coordinate information of the pixels of a plurality of specific parts (in this embodiment, the position of the fovea center and the position of the optic disc center) in each of the images acquired in step S504, first alignment information for generating the first composite image in S506 is generated.

[0052] Either the OCT map image 410 or the fundus frontal image 411 is moved, enlarged, and rotated so that the positions of the fovea center and the optic disc center of the OCT map image 410 and the fundus frontal image 411 match each other, and first alignment information for generating the first composite image is acquired. Note that under conditions such as the two acquired images being taken simultaneously, assuming there is no rotation between the images, the ratio of the distance between the fovea center and the optic disc center in the X-axis and Y-axis directions of the image is used as the magnification and enlarged, and the first alignment information for easily generating the first composite image can be acquired by translating the image so that the fovea center and the optic disc center overlap. Note that even when there are three or more specific parts to be aligned, similarly, the amount of movement, enlargement, and rotation is calculated so that the positions of the same parts of the OCT map image 410 and the fundus frontal image 411 overlap or the difference is minimized, and the first alignment information is acquired.

[0053] Next, in step S506, using the first alignment information calculated in step S505, the control means of the perimeter system 130 generates a first composite image, which is a superimposed image of the fundus frontal image 411 and the OCT map image 410. For example, a first composite image is generated by superimposing the OCT map image 410 on the fundus frontal image 411. At this time, a transmittance may be imparted to the OCT map image 410 to be displayed above so that the fundus frontal image 411 can be seen. Also, an operation to change the transmittance may be enabled while the first composite image is being displayed using a GUI for setting the transmittance. At this time, the coordinate information of the fovea center and the optic disc center of the newly generated first composite image is calculated and held.

[0054] Next, in step S507, the perimeter system 130 reads the perimetry data to be synthesized and displayed with the first composite image or the OCT map image 410.

[0055] Subsequently, in step S508, information (first information) indicating the positions of a plurality of specific parts of the OCT map image 410 (in this embodiment, the position of the fovea center and the position of the optic disc center) or the positions of a plurality of specific parts on the first composite image calculated in step S506 (in this embodiment, the position of the fovea center and the position of the optic disc center of the first composite image calculated in S506), which is to be synthesized with the image (hereinafter referred to as the perimetry image) based on the perimetry data read in step S507, is acquired. That is, in the determination of step S502, when it is determined that the fundus frontal image 411 corresponding to the OCT map image 410 read by the perimeter system 130 in S501 is included in the first data output from the output means 104, the information indicating the positions of a plurality of specific parts on the first composite image calculated in step S506 is acquired, and when it is determined that it is not included, the information (first information) indicating the positions of a plurality of specific parts on the OCT map image 410 is acquired.

[0056] In step S509, second alignment information for synthesizing the OCT map image 410 or the first composite image and the visual field measurement data is acquired. The visual field measurement data includes the fovea centralis which is the center of the visual field and the papilla central part where the blind spot is located, and depending on the type of visual field test, the positions corresponding to the respective fovea centralis and the positions corresponding to the papilla centralis can be specified. In accordance with that position, similar to step S505, second alignment information for generating a second composite image obtained by synthesizing the OCT map image 410 or the first composite image and the visual field measurement data is acquired. At this time, alignment may be performed in consideration of the distortion that occurs between the data acquired by the perimeter and the data acquired by the OCT device. In this case, the perimeter system 130 holds distortion distribution information, and while aligning the positions of the fovea centralis and the papilla centralis, the distortion distribution information is reflected in the entire image to deform the visual field measurement data. In the OCT map image 410 and the visual field measurement data, even if the portions corresponding to the fovea position and the papilla position are synthesized, the distribution therebetween is not necessarily uniform, and thus the distortion distribution information can be used as additional information for correcting that position. By deforming at least one of the OCT map image 410 and the visual field measurement data in accordance with the distortion distribution information, the correspondence between each position of the OCT map image and the visual field test result can be arranged more accurately. In this case, the perimeter system 130 holds distortion distribution information, and while aligning the positions of the fovea centralis and the papilla centralis, the distortion distribution information is reflected in the entire image to deform the visual field measurement image. Further, individual distortion may occur depending on the fundus shape of the patient in addition to the held distortion distribution information. In that case, the output means 104 of the OCT data processing device 100 outputs first data including the individual distortion distribution information, the perimeter system 130 receives it, acquires second alignment information based on the individual distortion distribution information, and can also acquire second alignment information that takes into account the difference in individual distortion. Note that the distortion distribution information may be, for example, map data showing the positional relationship between an image based on two-dimensional frontal data and the visual field measurement data, or may be generated from the visual field measurement image.

[0057] Finally, in step S510, the second alignment information obtained in step S509 is acquired, and a second composite image is generated by superimposing the OCT map image 410 or the first composite image and the visual field measurement data. At this time, similar to the method described in S506, a transparency process may be added to the superimposed image side and superimposed so that the position of the visual field defect site in the OCT map image 410 or the first composite image and the visual field measurement data can be compared. Alternatively, only a specific region such as a region with a visual field defect in the visual field measurement image may be extracted, and a visual field measurement image of only the specific region may be superimposed on the OCT map 410 image or the first composite image to generate a second composite image.

[0058] According to the above-described embodiment, in the visual field meter system 130, in order to superimpose and display an image that is two-dimensional front data based on three-dimensional OCT data or three-dimensional OCT motion contrast data or an image generated from two-dimensional front data and a visual field measurement image, the two-dimensional front data and first data including first information indicating the positions of a plurality of specific sites on the image based on the two-dimensional front data (in this embodiment, the position of the fovea centralis and the coordinate information of the optic disc center) are output from the OCT data processing apparatus 100. Thereby, in the visual field meter system 130, the alignment between the image based on the two-dimensional front data and the visual field measurement image can be efficiently performed.

[0059] Note that in this embodiment, an OCT map image is used as the two-dimensional frontal data included in the first data output by the OCT data processing device 100 and based on three-dimensional OCT data or two-dimensional frontal data based on three-dimensional OCT motion contrast data. However, the two-dimensional frontal data is not limited to this. The two-dimensional frontal data may be an OCT En Face image generated by projecting three-dimensional OCT data onto a specific reference plane, or an OCTA image that is a frontal image generated by projecting a specific layer region of a three-dimensional OCT motion contrast image onto a certain reference plane. Further, the two-dimensional frontal data may be a blood vessel density map showing the blood vessel region per unit area by binarizing the OCTA image, or a blood vessel length map showing the length of blood vessels per unit area by thinning the binarized image. Also, the image for generating a composite image by overlapping with the visual field measurement data may be a fundus frontal image such as a fundus camera image or an SLO image instead of the two-dimensional frontal data based on three-dimensional OCT data or three-dimensional OCT motion contrast data.

[0060] Also, in this embodiment, the output means 104 outputs the first data by the operator instructing the output of the two-dimensional frontal data, but the output may be performed automatically. In that case, for example, the output instruction of the OCT map in step S305 may be made triggered by the three-dimensional OCT data being taken in from the data acquisition means 101 and stored in the storage means 102. Also, in that case, the determination of whether transmission is possible and the activation of the trigger in steps S303 and S304 may be performed based on the three-dimensional OCT data taken in from the data acquisition means 101.

[0061] Furthermore, in this embodiment, as information indicating the positions of a plurality of specific parts on the image based on the two-dimensional frontal data included in the first data, the coordinate information of the pixels of the fovea centralis and the optic disc center on the image based on the two-dimensional frontal data is used. However, the information indicating the positions of the plurality of specific parts is not limited to this. For example, the size of the entire image may be defined in advance in units of millimeters or micrometers, and the information indicating the positions of the fovea centralis and the optic disc center when a predetermined position of the image such as the upper left of the image is used as a reference may be used.

[0062] Also, in this embodiment, in step S509, although the visual field measurement data was deformed to generate the second composite image, instead of deforming the visual field measurement data, the OCT map image 410 or the first composite image may be deformed to generate the second composite image. In that case, scaling, rotation, and reflection of distortion information are performed on the OCT map image 410 or the first composite image side. Note that it may be a process of deforming either the visual field measurement data or both the OCT map image 410 and the first composite image.

[0063] Furthermore, the report generated by the visual field measurement system 130 may be created using the two-dimensional frontal data based on the three-dimensional OCT data or three-dimensional OCT motion contrast data included in the first data, and information and data other than the visual field measurement data. For example, by reading and displaying inspection information such as the shooting date and time of the three-dimensional OCT data or three-dimensional OCT motion contrast data, and comparison data between the three-dimensional OCT data or three-dimensional OCT motion contrast data assigned to the upper and lower divided regions displayed in the sector display area 224 and the normal eye database, a report of the visual field measurement system including information other than the composite image of the two-dimensional frontal data based on the three-dimensional OCT data or three-dimensional OCT motion contrast data and the visual field measurement data (information related to the OCT side inspection and analysis information other than the two-dimensional frontal data used for generating the composite image) can be generated.

[0064] <Example 2> In Example 1, the OCT data processing device outputs the first data including the two-dimensional frontal data based on the three-dimensional OCT data or three-dimensional OCT motion contrast image, and information indicating the positions of a plurality of specific parts on the image based on the two-dimensional frontal data. This was an example where the visual field measurement system generated and displayed a composite image of the image based on the two-dimensional frontal data and the image based on the visual field measurement data.

[0065] On the one hand, in this embodiment, an example is given in which the second data output from the perimeter system 130 is input into the OCT data processing apparatus 100, and an image based on the perimetry data included in the second data is displayed together with the image based on the two-dimensional frontal data. When displaying the image based on the perimetry data, it is desirable to deform and display the perimetry data in accordance with the type of visual field examination and the range of the fundus frontal image displayed by the OCT data in order to compare it side by side with the OCT data to be displayed together.

[0066] Hereinafter, with reference to FIGS. 6 and 7, the input and display flow of the second data on the OCT data processing apparatus 100 according to this embodiment will be described. FIG. 6 shows an example of a report screen 600 before inputting the second data, which is displayed on the OCT data processing apparatus 100 according to this embodiment. FIG. 7 shows a flowchart of operations for inputting and displaying the second data according to this embodiment.

[0067] In step S701, the operator presses the import button 620 for the perimetry data on the report screen 600 displayed on the display means 110 of the OCT data processing apparatus 100, and by performing an operation of selecting the perimetry data by the operator from an unillustrated data selection screen that is displayed, the data acquisition means (also referred to as the input means) 101 captures (inputs) the second data including the perimetry data and stores it in the storage means 102. If the perimetry data has been stored in the storage means 102 in advance, specific perimetry data may be selected from the storage means 102.

[0068] Next, in step S702, the calculation means 111 calculates information indicating the positions of a plurality of specific parts on the image based on the two-dimensional frontal data that is currently being displayed on the display means 110 (that is, the first information, which is coordinate information in this embodiment). In this embodiment, the two-dimensional frontal data (that is, two-dimensional frontal data based on three-dimensional OCT data or three-dimensional motion contrast data) is an OCT En Face image, and the coordinate information of each position indicating the position of the center of the macula and the position of the center of the optic disc of the OCT En Face image 610 is calculated from the current display area.

[0069] Next, in step S703, the data acquisition means 101 reads information indicating the type of visual field examination performed when acquired by the visual field measurement system from the additional information of the visual field measurement data included in the second data acquired in step S701 (the fourth information which is information capable of specifying at least one position among a plurality of specific parts on the image based on the visual field measurement data). In this embodiment, it is assumed that the type of visual field examination read by the data acquisition means 101 is an examination of the visual field angle.

[0070] Next, in step S704, from the image based on the visual field measurement data and the information indicating the type of visual field examination (for example, information indicating the visual field angle of the examination) read in step S703, information indicating the positions of the same parts as the plurality of specific parts on the image based on the two-dimensional frontal data calculated in step S702 on the image based on the visual field measurement data is acquired. In this embodiment, similar to step S702, information (fifth information) indicating the position of the fovea centralis and the position of the optic disc center in the visual field measurement data is acquired. Here, the fovea centralis is the central visual field part of the visual field measurement data, and the optic disc center is calculated from the information indicating the type of visual field examination. That is, information (fifth information) indicating the positions of a plurality of specific parts on the image based on the visual field measurement data is calculated from at least one of the visual field measurement data and the information indicating the type of visual field examination.

[0071] Next, in step S705, the data acquisition means 101 acquires distortion distribution information between the data acquired by the OCT imaging device and the data acquired by the perimeter, which is necessary for aligning the image based on the visual field measurement data acquired in step S701 and the image based on the two-dimensional frontal data. The distortion distribution information may be acquired by the data acquisition means 101 from the storage means 102 and used, which is prepared in advance for aligning the image based on the two-dimensional frontal data and the visual field measurement data, or the data acquisition means 101 may acquire the distortion distribution information included in the second data output from the visual field measurement system together with the visual field measurement data.

[0072] Next, in step S706, using the data obtained in steps S702, S704, and S705 or the information indicating the positions of a plurality of specific parts on the image and the distortion distribution information, information regarding the alignment (third alignment information) between the image based on the two-dimensional frontal data and the image based on the visual field measurement data is obtained. Here, in order to align the positions of the fovea centralis and the optic disc center of the image based on the two-dimensional frontal data and the image based on the visual field measurement data, respectively, the amount of movement, enlargement, and rotation of at least one of the data is determined. At this time, using the distortion distribution information obtained in step S705, the positions of the fovea centralis, the optic disc center, and the position considering the distortion are adjusted to calculate the information regarding the alignment.

[0073] Finally, in step S707, using the information regarding the alignment calculated in step S706, the display control means 103 generates a composite image of the image based on the two-dimensional frontal data and the image based on the visual field measurement data, which are displayed on the display means 110, and displays it on the display means 110. Note that the image based on the visual field measurement data described here may be any image based on the data calculated by the perimeter, and may be an image corresponding to the visual field measurement data calculated by the perimeter, or may be an image generated based on the data extracted from the data calculated by the perimeter. As an example of the latter, it is an image regarding the information indicating the visual field defect extracted from the data calculated by the perimeter. In such a case, for example, as shown in FIG. 6, the display control means 103 may display an image in which an index 611 of the area indicating the visual field defect is superimposed on the position corresponding to the area indicating the visual field defect extracted from the visual field measurement data of the OCT En Face image 610.

[0074] According to the above-described present embodiment, on the OCT data processing apparatus 100, alignment is performed between an image based on the perimetry measurement data output by the perimetry system 130 and an image based on two-dimensional frontal data based on the three-dimensional OCT data or three-dimensional OCT motion contrast data acquired by the OCT data processing apparatus 100, and then superimposed display can be performed. Thereby, it becomes possible to easily compare the information obtained from each of the image based on the perimetry measurement data and the image based on the two-dimensional frontal data acquired by the OCT data processing apparatus 100.

[0075] In the present embodiment, an OCT En Face image is used as the image based on the two-dimensional frontal data to be superimposed and displayed with the image based on the perimetry measurement data. However, any image based on the two-dimensional frontal data based on the three-dimensional OCT data or three-dimensional OCT motion contrast data may be used. For example, a two-dimensional frontal analysis map generated based on the three-dimensional OCT data or three-dimensional OCT motion contrast data may be used. Further, as the image to be superimposed and displayed with the image based on the perimetry measurement data, instead of the two-dimensional frontal data based on the three-dimensional OCT data or three-dimensional OCT motion contrast data, a fundus camera image or an SLO image acquired by a fundus camera may be used.

[0076] <Example 3> This embodiment is an example in which the OCT data processing apparatus 100 highlights a region indicating a visual field defect specified from an image based on the perimetry measurement data included in the second data acquired from the perimetry system 130 on an image based on the two-dimensional frontal data.

[0077] Based on the visual field measurement data included in the second data acquired by the data acquisition means 101, an area indicating visual field defect is specified, and with reference to FIGS. 8 and 9, a flow of highlighting the area specified on the image based on the two-dimensional frontal data acquired by the OCT data processing apparatus 100 will be described. FIG. 8 is a report screen 800 according to this embodiment, in which the area indicating the specified visual field defect is highlighted on the image based on the two-dimensional frontal data. Further, FIG. 9 is a flowchart showing an operation flow for highlighting the area indicating the visual field defect according to this embodiment.

[0078] (Operation flow) Steps S901 to S906 are the same steps as steps S701 to S706 in FIG. 7, respectively, except that in step S702 of the second embodiment, instead of using the OCT En Face image as the two-dimensional frontal data, an analysis map of the three-dimensional OCT data or the three-dimensional OCT motion contrast data is used.

[0079] In step S907, the calculation means 111 acquires information regarding the area indicating the visual field defect from the visual field measurement data acquired from the visual field measurement system 130. Specifically, the area indicating the visual field defect is specified. For example, a threshold value is determined to perform binarization of the visual field measurement data to separate the area indicating the visual field defect and the area that is not. Also, when there are gaps between the points indicating the visual field defect in displaying the area indicating the visual field defect, the adjacent points indicating the visual field defect are grouped to extract the area indicating the visual field defect.

[0080] In step S908, an index 811 indicating the area indicating the visual field defect is displayed in the area corresponding to the area indicating the visual field defect on the analysis map image 810 by using the information regarding the alignment calculated in step S906 so that the visual field defect area extracted in step S907 can be seen. Here, the display control means 103 highlights the index 811 indicating the visual field defect area as an area surrounded by a dashed line. In addition to surrounding it with a dashed line, the area indicating the visual field defect can also be highlighted by displaying only the map of the overlapping area of the analysis map image with the area indicating the visual field defect.

[0081] According to the above-described embodiment, on the image based on the two-dimensional frontal data, by highlighting the region indicating the visual field defect, for example, without superimposing the visual field measurement data, the region indicating the visual field defect in the two-dimensional frontal data can be easily confirmed.

[0082] <Example 4> This embodiment is an example of preferentially displaying an OCT analysis map with a high correlation with the information on the region indicating the visual field defect from the two-dimensional frontal data based on the three-dimensional OCT data or the three-dimensional OCT motion contrast data stored in the storage means 102 of the OCT data processing apparatus 100, using the information on the region indicating the visual field defect based on the visual field measurement data acquired from the visual field meter system 103.

[0083] With reference to FIGS. 10 and 11, a flow of identifying the region indicating the visual field defect based on the read visual field measurement data (acquisition of information on the region indicating the visual field defect) and displaying an image based on the two-dimensional frontal data having a high correlation with the result will be described. FIG. 10 is a report screen 1000 for priority map image display that mainly displays the two-dimensional frontal data having the highest correlation value with respect to the identified region indicating the visual field defect according to this embodiment. FIG. 11 is a flowchart of the operation for mainly displaying an image based on the two-dimensional frontal data having the highest correlation value according to this embodiment.

[0084] (Operation flow) Steps S1101 to S1107 are the same steps as steps S901 to S907 (FIG. 9) of Embodiment 3, respectively.

[0085] In step S1108, an operation result (here, for example, a correlation value) regarding the correlation between the region indicating the visual field defect specified based on the visual field measurement data acquired from the perimeter system 103 (information regarding the region indicating the acquired visual field defect) and the OCT analysis map which is a plurality of two-dimensional frontal data stored in the storage means 102 is calculated. For example, when the analysis map is an analysis map showing the comparison between the OCT data or OCT motion contrast data acquired by the OCT data processing apparatus 100 and the normal eye database, the ratio at which the region with a large difference from the data of the normal eye and the region indicating the visual field defect specified from the visual field measurement data match is calculated as the correlation value. When the analysis map is a layer thickness map showing the thickness of each layer, the ratio at which the region specified as the thin retina region from the layer thickness map and the region indicating the visual field defect specified from the visual field measurement data match is calculated as the correlation value.

[0086] In step S1109, the control means 105 selects the first analysis map (high correlation map image) 1030 with the highest correlation value from the correlation values regarding each analysis map obtained in step S1108, and the display control means 103 displays it on the display means 110. At this time, the first analysis map 1030 displays, side by side, images 1020 in which an index indicating the visual field defect region is superimposed on the first analysis map so that it can be compared with the region indicating the visual field defect specified in step S1107. For the analysis maps and the like which are other two-dimensional frontal data, they may be displayed side by side smaller than the first analysis map 1030 and the images 1020. Note that the image to be displayed is not limited to the image showing the highest correlation value, and an image based on the two-dimensional frontal data selected for display based on the correlation values calculated for each of the plurality of two-dimensional frontal data in step S1108 may be displayed.

[0087] According to the above-described embodiment, among the analysis maps that are images based on the two-dimensional frontal data stored in the storage means 102 of the OCT data processing apparatus 100, the first analysis map having a high correlation with the information regarding the region indicating the visual field defect specified based on the read visual field measurement data is preferentially displayed on the report screen of the display unit 110, so that it becomes possible to efficiently grasp the tendency of the patient's symptoms. If there is no analysis map showing a correlation value equal to or higher than a certain reference value, control may be performed not to display an image in the display area for displaying the first analysis map 1030.

[0088] In addition, if the correlation value is not high overall, for example, the calculated correlation value can also be displayed together with each analysis map. Thereby, the operator can also make a judgment based on the correlation value.

[0089] As described above, the embodiment has been described in detail. However, the disclosed technology can be implemented, for example, as an embodiment such as a system, an apparatus, a method, a control program for an inspection apparatus, or a recording medium (storage medium). Specifically, it may be applied to a system composed of a plurality of devices (for example, a host computer, an interface device, an imaging device, a web application, etc.), or may be applied to an apparatus composed of a single device.

[0090] Further, the present disclosure can also be realized by supplying a recording medium (or storage medium) recording software program code (computer program) for realizing one or more functions of the above-described embodiment to a system or an apparatus, and then the computer (or CPU or MPU) of the system or apparatus reads and executes the program code stored in the recording medium. Needless to say, such a recording medium is a computer-readable recording medium. In this case, the program code itself read from the recording medium realizes the functions of the above-described embodiment, and the recording medium recording the program code is included in the present disclosure.

[0091] The configuration of the measurement optical system in the ophthalmic apparatus according to the above-described embodiment is an example and may be arbitrarily changed according to a desired configuration.

[0092] Note that all of the above-described embodiments of the present disclosure are merely examples of implementation when implementing the present disclosure, and the technical scope of the present disclosure should not be construed in a limited manner by these. That is, the present disclosure can be implemented in various forms without departing from its technical idea or its main features.

[0093] Here, the disclosure of the embodiments of the present disclosure includes the following configurations, control methods, and programs.

[0094] [Configuration 1] An OCT data processing device connectable to a system for acquiring visual field measurement data, wherein the OCT data processing device has output means for outputting first data that can be input to the system, wherein the first data is OCT data processing device including two-dimensional frontal data based on three-dimensional OCT data or three-dimensional OCT motion contrast data of an eye to be examined, and first information indicating positions of a plurality of specific parts on an image based on the two-dimensional frontal data.

[0095] [Configuration 2] The OCT data processing device according to Configuration 1, wherein the first information is position information of pixels corresponding to the plurality of specific parts on an image based on the two-dimensional frontal data.

[0096] [Configuration 3] The OCT data processing device according to Configuration 1 or 2, wherein the image based on the two-dimensional frontal data is two-dimensional frontal data that is an image file or an image generated from the two-dimensional frontal data.

[0097] [Configuration 4] The image based on the two-dimensional frontal data is at least one of an OCT En Face image generated based on the three-dimensional OCT data, an analysis map image generated based on the three-dimensional OCT data, an OCTA image generated based on the three-dimensional OCT motion contrast data, and a vascular density map image based on the three-dimensional OCT motion contrast data. The OCT data processing apparatus according to any one of Configurations 1 to 3.

[0098] [Configuration 5] The OCT data processing apparatus according to Configuration 4, wherein the analysis map image generated based on the three-dimensional OCT data is a layer thickness map image or a comparison map image of the layer thickness with a normal eye database.

[0099] [Configuration 6] The OCT data processing apparatus according to any one of Configurations 1 to 5, wherein the first data further includes second information different from the first information.

[0100] [Configuration 7] The OCT data processing apparatus according to Configuration 6, wherein the second information includes at least one or more of information regarding the resolution of the image based on the two-dimensional frontal data, information regarding the size on the fundus based on the image acquired by the OCT data processing apparatus, information regarding the type of the image based on the two-dimensional frontal data, information regarding the range in which the image based on the two-dimensional frontal data is generated, information for identifying the eye to be examined, the shooting date and time, and the shooting mode.

[0101] [Configuration 8] The OCT data processing apparatus according to Configuration 6 or 7, wherein the second information includes a fundus frontal image of the eye to be examined.

[0102] [Configuration 9] The OCT data processing apparatus according to any one of Configurations 6 to 8, wherein the second information includes third information which is information indicating the positions of the plurality of specific parts on the fundus frontal image of the eye to be examined.

[0103] [Configuration 10] The OCT data processing apparatus according to any one of Configurations 1 to 9, wherein the output means transmits the first data to the system that acquires the visual field measurement data.

[0104] [Configuration 11] The OCT data processing apparatus according to any one of Configurations 1 to 9, wherein the output means transmits the first data to a data storage destination that can be connected to either the system that acquires the visual field measurement data or the OCT data processing apparatus.

[0105] [Configuration 12] The OCT data processing apparatus according to any one of Configurations 1 to 11, wherein each of the plurality of specific sites is a site within a part having different anatomical features of the eye to be examined.

[0106] [Configuration 13] The OCT data processing apparatus according to any one of Configurations 1 to 12, wherein the plurality of specific sites are the optic disc center and the fovea center.

[0107] [Configuration 14] The OCT data processing apparatus, has determination means for determining whether output to the system that acquires the visual field measurement data is possible, and when determined to be outputtable by the determination means, the output means outputs the first data, according to any one of Configurations 1 to 13.

[0108] [Configuration 15] The OCT data processing apparatus, has display means, display control means for controlling the display to the display means, instruction reception means for receiving an instruction from an operator, and the display control means displays on the display means a screen including an image based on the two-dimensional front data and an operation area for receiving an instruction from the operator. By the instruction receiving means receiving an instruction from the operator using the operation in the operation area, The output means outputs the OCT data processing apparatus according to any one of Configurations 1 to 14 that outputs the first data.

[0109] [Configuration 16] An image based on the two-dimensional frontal data displayed by the display control means on the display means is an image based on the two-dimensional frontal data of both the left and right eyes of the eye to be examined, By the instruction receiving means receiving an instruction from the operator using the operation in the operation area, The output means outputs each of the images based on the two-dimensional frontal data of both the left and right eyes of the eye to be examined, the OCT data processing apparatus according to Configuration 15.

[0110] [Configuration 17] The second information includes distortion distribution information between data obtained by an OCT imaging device that obtains three-dimensional OCT data or three-dimensional OCT motion contrast data of the eye to be examined and data obtained by a system that obtains the visual field measurement data, the OCT data processing apparatus according to any one of Configurations 6 to 9.

[0111] [Configuration 18] An OCT data processing apparatus connectable to a system that obtains visual field measurement data, An acquisition means for acquiring two-dimensional frontal data based on three-dimensional OCT data or three-dimensional OCT motion contrast data of the eye to be examined, An input means for inputting second data output from the system, and has, The second data is, The visual field measurement data and fourth information that is information capable of specifying at least one position of a plurality of specific parts on an image based on the visual field measurement data, the OCT data processing apparatus characterized by including.

[0112] [Configuration 19] The OCT data processing apparatus according to Configuration 18, which acquires fifth information indicating positions of a plurality of specific parts on an image based on the visual field measurement data from at least one of the visual field measurement data and the fourth information.

[0113] [Configuration 20] The apparatus further includes alignment means for aligning an image based on the visual field measurement data and an image based on the two-dimensional frontal data, The OCT data processing apparatus according to Configuration 19, wherein the alignment means performs alignment between the image based on the visual field measurement data and the image based on the two-dimensional frontal data using the fifth information.

[0114] [Configuration 21] The alignment means, The fifth information, The OCT data processing apparatus according to Configuration 20, which performs the alignment using the first information indicating positions of the plurality of specific parts on the image based on the two-dimensional frontal data. The OCT data processing apparatus according to Configuration 20, which performs the alignment using the first information indicating positions of the plurality of specific parts on the image based on the two-dimensional frontal data.

[0115] [Configuration 22] After the alignment by the alignment means, The OCT data processing apparatus according to Configuration 20 or 21, which includes composite image generation means for generating a composite image of the image based on the visual field measurement data and the image based on the two-dimensional frontal data.

[0116] [Configuration 23] The OCT data processing apparatus, Further includes distortion distribution information acquisition means for acquiring distortion distribution information between data acquired by an OCT imaging apparatus that acquires three-dimensional OCT data or three-dimensional OCT motion contrast data of the eye to be examined and data acquired by a system that acquires the visual field measurement data, The OCT data processing apparatus according to Configuration 22, wherein the alignment means performs the alignment using the distortion distribution information.

[0117] [Configuration 24] The OCT data processing device according to any one of configurations 18 to 23, wherein the fourth information is information regarding the type of examination for acquiring the visual field measurement data.

[0118] [Configuration 25] The OCT data processing device, further includes display control means, wherein the display control means, displays an image based on the two-dimensional frontal data on a display means, and based on information regarding a visual field defect region included in the second data input by the input means, highlights a region on the image based on the two-dimensional frontal data corresponding to the visual field defect region. The OCT data processing device according to any one of configurations 18 to 24.

[0119] [Configuration 26] The OCT data processing device, further includes arithmetic means, storage means, and display control means, wherein the storage means stores images based on a plurality of types of the two-dimensional frontal data, the arithmetic means performs an operation regarding the correlation between information regarding a visual field defect region included in the second data input by the input means and the images based on the plurality of types of the two-dimensional frontal data, based on the operation result, the display control means selects an image from the images based on the plurality of types of the two-dimensional frontal data and displays it on the display means. The OCT data processing device according to any one of configurations 18 to 25.

[0120] [Control Method 1] A control method for an OCT data processing device connectable to a system that acquires visual field measurement data, the method including: a step of the OCT data processing device outputting first data inputtable to the system, wherein the first data, A control method for an OCT data processing apparatus, including two-dimensional frontal data based on three-dimensional OCT data or three-dimensional OCT motion contrast data of an eye to be examined, and first information indicating positions of a plurality of specific parts on an image based on the two-dimensional frontal data.

[0121] [Control Method 2] A control method for an OCT data processing apparatus connectable to a system for acquiring visual field measurement data, comprising a step of acquiring two-dimensional frontal data based on three-dimensional OCT data or three-dimensional OCT motion contrast data of an eye to be examined, and a step of inputting second data output from the system, wherein the second data is an OCT data processing apparatus control method including the visual field measurement data and fourth information that is information capable of specifying positions of a plurality of specific parts on an image based on the visual field measurement data.

[0122] [Program 1] A program for executing the control method of the OCT data processing apparatus described in Control Method 1 or Control Method 2.

Explanation of Signs

[0123] 100 OCT data processing apparatus 101 Data acquisition means 102 Storage means 103 Display control means 104 Output means 105 Control means 106 Judgment means 107 Instruction reception means 108 Output control means 109 Image generation means 110 Display means 111 Calculation means 120 Operation means 130 Visual field meter system

Claims

1. An OCT data processing device connectable to a system for acquiring visual field measurement data, wherein the OCT data processing device, has output means for outputting first data inputtable to the system, and the first data, includes two-dimensional frontal data based on three-dimensional OCT data or three-dimensional OCT motion contrast data of an eye to be examined, and first information indicating positions of a plurality of specific parts on an image based on the two-dimensional frontal data. The OCT data processing device is characterized by this.

2. The OCT data processing device according to claim 1, wherein the first information is position information of pixels corresponding to the plurality of specific parts on the image based on the two-dimensional frontal data.

3. The OCT data processing device according to claim 1, wherein the image based on the two-dimensional frontal data is two-dimensional frontal data that is an image file or an image generated from the two-dimensional frontal data.

4. The OCT data processing device according to claim 1, wherein the image based on the two-dimensional frontal data is at least one of an OCT En Face image generated based on the three-dimensional OCT data, an analysis map image generated based on the three-dimensional OCT data, an OCTA image generated based on the three-dimensional OCT motion contrast data, and a vessel density map image based on the three-dimensional OCT motion contrast data.

5. The OCT data processing device according to claim 4, wherein the analysis map image generated based on the three-dimensional OCT data is a layer thickness map image or a comparison map image of layer thickness with a normal eye database.

6. The OCT data processing device according to claim 1, wherein the first data further includes second information different from the first information.

7. The OCT data processing device according to claim 6, wherein the second information includes at least one or more of information regarding the resolution of an image based on the two-dimensional front data, information regarding the size on the fundus oculi based on an image acquired by the OCT data processing device, information regarding the type of the image based on the two-dimensional front data, information regarding the range in which the image based on the two-dimensional front data is generated, information for specifying the eye to be examined, the date and time of imaging, and the imaging mode.

8. The OCT data processing device according to claim 6, wherein the second information includes a fundus front image of the eye to be examined.

9. The OCT data processing device according to claim 8, wherein the second information includes third information which is information indicating positions of the plurality of specific parts on the fundus front image of the eye to be examined.

10. The OCT data processing device according to claim 1, wherein the output means transmits the first data to a system that acquires the visual field measurement data.

11. The OCT data processing device according to claim 1, wherein the output means transmits the first data to a data storage destination that is connectable to both a system that acquires the visual field measurement data and the OCT data processing device.

12. The OCT data processing device according to claim 1, wherein each of the plurality of specific parts is a part within a part having different anatomical features of the eye to be examined.

13. The OCT data processing device according to claim 1, wherein the plurality of specific parts are the optic disc center and the fovea center.

14. The OCT data processing device has determination means for determining whether or not output to a system that acquires the visual field measurement data is possible, The OCT data processing apparatus according to claim 1, wherein when it is determined by the determination means that output is possible, the output means outputs the first data.

15. The OCT data processing apparatus, a display means, a display control means for controlling the display on the display means, an instruction reception means for receiving an instruction from an operator, and has, the display control means displays on the display means a screen including an image based on the two-dimensional frontal data and an operation area for receiving an instruction from the operator, when the instruction reception means receives an instruction from the operator using an operation on the operation area, the output means outputs the first data, the OCT data processing apparatus according to claim 1.

16. an image based on the two-dimensional frontal data, which the display control means displays on the display means, is an image based on the two-dimensional frontal data of both the left and right eyes of the eye to be examined, when the instruction reception means receives an instruction from the operator using an operation on the operation area, the output means outputs each of the images based on the two-dimensional frontal data of both the left and right eyes of the eye to be examined, the OCT data processing apparatus according to claim 15.

17. The OCT data processing apparatus according to claim 6, wherein the second information includes distortion distribution information between data acquired by an OCT imaging apparatus that acquires three-dimensional OCT data or three-dimensional OCT motion contrast data of the eye to be examined and data acquired by a system that acquires the visual field measurement data.

18. An OCT data processing apparatus connectable to a system for acquiring visual field measurement data, an acquisition means for acquiring two-dimensional frontal data based on three-dimensional OCT data or three-dimensional OCT motion contrast data of the eye to be examined, input means for inputting the second data output from the system, wherein the second data is an OCT data processing apparatus, characterized in that it includes the visual field measurement data and fourth information that is information capable of specifying at least one position among a plurality of specific parts on an image based on the visual field measurement data.

19. The OCT data processing apparatus according to claim 18, characterized in that fifth information, which is information indicating positions of a plurality of specific parts on an image based on the visual field measurement data, is obtained from at least one of the visual field measurement data and the fourth information.

20. further comprising alignment means for aligning an image based on the visual field measurement data and an image based on the two-dimensional frontal data, The OCT data processing apparatus according to claim 19, characterized in that the alignment means performs alignment of an image based on the visual field measurement data and an image based on the two-dimensional frontal data using the fifth information.

21. wherein the alignment means uses the fifth information and first information, which is information indicating positions of the plurality of specific parts on an image based on the two-dimensional frontal data, to perform the alignment, the OCT data processing apparatus according to claim 20.

22. After the alignment by the alignment means, The OCT data processing apparatus according to claim 21, characterized in that it has composite image generation means for generating a composite image of an image based on the visual field measurement data and an image based on the two-dimensional frontal data.

23. the OCT data processing apparatus Furthermore, there is further provided a distortion distribution information acquisition means for acquiring distortion distribution information between data acquired by an OCT imaging device that acquires three-dimensional OCT data or three-dimensional OCT motion contrast data of the eye to be examined and data acquired by a system that acquires the visual field measurement data. The OCT data processing apparatus according to claim 22, wherein the alignment means performs the alignment using the distortion distribution information. **Claim 24** The OCT data processing apparatus according to claim 18, wherein the fourth information is information regarding the type of examination for which the visual field measurement data was acquired. **Claim 25** The OCT data processing apparatus further includes a display control means. The display control means displays an image based on the two-dimensional frontal data on a display means, and highlights a region on the image based on the two-dimensional frontal data corresponding to the visual field defect region based on information regarding the visual field defect region included in the second data input by the input means. The OCT data processing apparatus according to claim 18. **Claim 26** The OCT data processing apparatus further includes an arithmetic means, a storage means, and a display control means. The storage means stores images based on a plurality of types of the two-dimensional frontal data. The arithmetic means performs an operation regarding the correlation between the information regarding the visual field defect region included in the second data input by the input means and the images based on the plurality of types of the two-dimensional frontal data. Based on the operation result, the display control means selects an image from the images based on the plurality of types of the two-dimensional frontal data and displays it on the display means. The OCT data processing apparatus according to claim 18. **Claim 27** A control method for an OCT data processing apparatus connectable to a system for acquiring visual field measurement data. The OCT data processing device outputs first data that can be input into the system, and the first data includes two-dimensional frontal data based on three-dimensional OCT data or three-dimensional OCT motion contrast data of the eye to be examined, and first information indicating positions of a plurality of specific parts on an image based on the two-dimensional frontal data. A control method for an OCT data processing device, characterized in that it includes these.

28. A control method for an OCT data processing device connectable to a system that acquires visual field measurement data, the method comprising: acquiring two-dimensional frontal data based on three-dimensional OCT data or three-dimensional OCT motion contrast data of the eye to be examined, and inputting second data output from the system. The second data includes the visual field measurement data, and fourth information that is information capable of specifying positions of a plurality of specific parts on an image based on the visual field measurement data. A control method for an OCT data processing device, characterized in that it includes these.

29. A program for executing the control method for an OCT data processing device according to claim 27 or 28.

Images