Aqueous composition

Abstract

To provide an aqueous composition containing 1 mass% or more of oligosaccharide, the aqueous composition exhibiting superior precipitation suppression effect of the oligosaccharide.SOLUTION: An aqueous composition containing the following components (A) to (C): (A) 1 mass% or more of oligosaccharide, (B) a polyhydric alcohol having an IOB value of 4.5 to 5.5, and (C) a polyhydric alcohol having an IOB value of 1.5 to 3.5.SELECTED DRAWING: None

Description

[Technical Field]

[0001] The present invention relates to an aqueous composition, a method for inhibiting precipitation of oligosaccharides using the same, and a composition for inhibiting precipitation of oligosaccharides. [Background technology]

[0002] Internal factors such as aging and stress, as well as external factors such as ultraviolet rays and dry air, can cause skin problems such as age spots, freckles, wrinkles, sagging, and even clogged pores. Clogged pores in particular can lead to blackheads, enlarged pores, rough pores, redness, acne, and seborrheic dermatitis, so many people want to improve their condition, and various product developments are being considered. Known methods for treating clogged pores include chemical peeling, in which a chemical is applied to the skin to dissolve or peel off keratin, physical removal using scrubs, and exfoliation using wipe-off cosmetics. Wipe-off cosmetics, in particular, involve moistening cosmetic cotton or nonwoven fabric with lotion and wiping it off the surface of the skin, making them useful as a method that places less strain on the skin. Furthermore, in recent years, research into ingredients effective against clogged pores has progressed. For example, technology for a total secretion regulator containing oligosaccharides as an active ingredient has been disclosed, and the effectiveness of oligosaccharides against clogged pores is expected (see, for example, Patent Document 1).

[0003] However, oligosaccharides such as trehalose are highly crystalline, and when they are incorporated in large amounts into preparations or compositions such as cosmetics or topical skin preparations, crystal precipitation becomes a problem. In response to this, a technology has been disclosed for suppressing crystal precipitation of maltooligosaccharide in a cosmetic composition containing at least maltooligosaccharide, an alkyl ether having a certain average number of added moles of polyoxyethylene (POE), and at least one of an alkyl ether having a certain average number of added moles of polyoxyethylene (POE) and polyoxypropylene (POP), a dibasic acid diester, and a certain content of ethanol (see, for example, Patent Document 2). [Prior art documents] [Patent documents]

[0004] [Patent Document 1] International Publication No. 2022 / 024886 [Patent Document 2] Japanese Patent Application Laid-Open No. 2011-153122 Summary of the Invention [Problem to be solved by the invention]

[0005] However, the technology of Patent Document 2 requires a high blending rate of 50% by mass or more of ethanol, which can cause dryness or irritation in some cases, and there is room for improvement when it comes to applying it to the skin of the entire face, etc. Furthermore, in order to exert a greater effect on clogged pores (such as inhibiting the formation of keratin plugs), a high concentration of oligosaccharides is required, but there have been few reports on how to inhibit the crystal precipitation of oligosaccharides at high concentrations.

[0006] Therefore, the present invention aims to provide an aqueous composition containing 1% by mass or more, more preferably 3% by mass or more, of oligosaccharides, which has an excellent effect of inhibiting precipitation of oligosaccharides by using a polyhydric alcohol having an IOB value of 4.5 to 5.5 and a polyhydric alcohol having an IOB value of 1.5 to 3.5. [Means for solving the problem]

[0007] In view of this situation, the present inventors conducted extensive research and discovered that the above-mentioned problems can be solved by an aqueous composition containing 1% by mass or more of oligosaccharides, a polyhydric alcohol having an IOB value of 4.5 to 5.5, and a polyhydric alcohol having an IOB value of 1.5 to 3.5, thereby completing the present invention.

[0008] That is, the present invention provides the following. [1] The following components (A) to (C): (A) Oligosaccharides 1% by mass or more (B) Polyhydric alcohols with an IOB value of 4.5 to 5.5 (C) Polyhydric alcohols with an IOB value of 1.5 to 3.5 The aqueous composition comprises: [2] The aqueous composition according to [1] above, wherein the component (A) is trehalose. [3] The aqueous composition according to [1] or [2], wherein the mass ratio (A) / [(B)+(C)] of the content of the component (A) to the total content of the component (B) and the component (C) is 0.01 to 1. [4] The aqueous composition according to the above [1] or [2], wherein the total content of the component (B) and the component (C), (B)+(C), is 3 to 30 mass %. [5] The aqueous composition according to [1] or [2] above, wherein the content of the component (A) is 3% by mass or more. [6] The aqueous composition according to the above [1] or [2] further contains a component (D) a nonionic surfactant. [7] The aqueous composition according to [6] above, wherein the component (D) is at least one selected from the group consisting of a silicone surfactant and a polyoxyalkylene fatty acid alkanolamide. [8] The aqueous composition according to the above item [1] or [2] further contains a component (E) an alkylene oxide derivative represented by general formula (1). Z-{O-(EO)a-(PO)b-(BO)cH}n (1) (In formula (1), n ​​is an integer of 1 to 4, Z is a residue obtained by removing n hydroxy groups from a hydrogen atom or a polyhydric alcohol having 2 to 4 hydroxyl groups, EO is an oxyethylene group, PO is an oxypropylene group, and BO is an oxybutylene group. a, b, and c are the average numbers of moles of EO, PO, and BO added, respectively, and are values ​​of 0≦a≦50, 0≦b≦50, and 0≦c≦5. a, b, and c are not all 0, and when a and b are not 0, the mass ratio (PO / EO) is 1 / 5 to 5 / 1. EO and PO may be added randomly or in blocks, and when n is 2 or greater, multiple a's, b's, and c's may be the same or different, and when Z is a hydrogen atom, n is 1.) [9] A cosmetic or topical skin preparation containing the aqueous composition according to [1] or [2] above.

[10] The cosmetic or topical skin preparation according to [9] above is for wiping use.

[11] This method uses component (B) a polyhydric alcohol having an IOB value of 4.5 to 5.5 and component (C) a polyhydric alcohol having an IOB value of 1.5 to 3.5 to suppress precipitation of component (A) oligosaccharides.

[12] The composition for inhibiting precipitation of oligosaccharides (Component (A)) contains, as active ingredients, component (B) a polyhydric alcohol having an IOB value of 4.5 to 5.5 and component (C) a polyhydric alcohol having an IOB value of 1.5 to 3.5. [Effects of the Invention]

[0009] The present invention provides an aqueous composition containing 1% by mass or more, more preferably 3% by mass or more, of oligosaccharides, which has an excellent effect of inhibiting precipitation of oligosaccharides by using a polyhydric alcohol having an IOB value of 4.5 to 5.5 and a polyhydric alcohol having an IOB value of 1.5 to 3.5. Furthermore, the aqueous composition of the present invention is excellent in that it leaves the skin feeling non-sticky and smooth after application. DETAILED DESCRIPTION OF THE INVENTION

[0010] Hereinafter, embodiments of the present invention will be described. However, the present invention is not limited to only the following embodiments. In this specification, the range "X to Y" includes X and Y and means "X or more and Y or less." Furthermore, unless otherwise specified, operations and measurements of physical properties, etc. are performed under conditions of room temperature (25°C) and relative humidity of 40%RH.

[0011] The "IOB value" in the present invention is a value determined based on the Organic Conceptual Diagram (Fujita Atsushi, Prediction of Organic Compounds and Organic Conceptual Diagram, Chemistry Vol. 11, No. 10 (1957) 719-715). More specifically, this Organic Conceptual Diagram defines the degree of physical properties of a compound, primarily due to van der Waals forces, as "organic," and the degree of physical properties primarily due to electrical affinity, as "inorganic." The IOB value is an index showing the balance between inorganic and organic properties, and is expressed as IOB value = inorganic value / organic value. A compound with a higher IOB value is said to exhibit higher hydrophilic and polar properties.

[0012] (Component (A): Oligosaccharide)

[0013] The component (A) oligosaccharide used in the present invention has a sugar chain structure in which 2 to 10 monosaccharides are linked together. Examples of monosaccharides include tetroses such as erythrulose, erythrose, and threose; pentoses such as arabinose, xylose, lyxose, ribose, xylulose, and ribulose; hexoses such as galactose, glucose, talose, mannose, sorbose, tagatose, psicose, and fructose; branched sugars such as apiose and hamamelose; amino sugars such as glucosamine and galactosamine; and derivatives of these monosaccharides.

[0014] Oligosaccharides include homooligosaccharides containing only one of the above-mentioned monosaccharides, and heterooligosaccharides containing two or more of them. Examples of homooligosaccharides include xylooligosaccharides such as xylobiose, xylotriose, xylotetraose, and xylopentaose; galactooligosaccharides such as agarobiose and carabiose; glucooligosaccharides such as maltose, maltotriose, maltotetraose, maltopentaose, isomaltose, sophorose, cellobiose, cellotriose, cellotetraose, cellopentaose, trehalose, neotrehalose, and isotrehalose; mannooligosaccharides; and fructooligosaccharides such as inulobiose, inulotriose, inulotetraose, and inulopentaose. Examples of heterooligosaccharides include vicianose, isoprimeverose, sambubiose, primeverose, lycotetraose, solabioose, melibiose, manninotriose, lactose, licobiose, lycotriose, epicellobiose, sucrose, turanose, maltulose, isokestose, erlose, kestose, gentianose, lactulose, epigentibiose, isolikunose, umbelliferose, sesamoose, raffinose, lykunose, lobinobiose, silanobiose, rutinose, chacotriose, solatriose, and α-glucan oligosaccharides (glucose oligomers with a degree of polymerization of 2 to 10). In the present invention, non-reducing oligosaccharides such as sucrose, trehalose, erlose, raffinose, and kestose are preferred, non-reducing disaccharides such as sucrose and trehalose are more preferred, and trehalose is particularly preferred.

[0015] Trehalose is a disaccharide formed by the 1,1-glycosidic bond between two α-glucose units, and is also called α,α-trehalose. As used herein, trehalose includes anhydrous trehalose and hydrates such as a dihydrate.

[0016] In the present invention, the content of component (A) in the aqueous composition is, from the viewpoint of its effectiveness against clogged pores, such as inhibiting keratin plug formation, a lower limit of 1% by mass (hereinafter, simply "% by mass" will be abbreviated as "%") or more, more preferably 2% or more, and even more preferably 3% or more. The upper limit is not particularly limited, but is preferably 15% or less, more preferably 10% or less, even more preferably 8% or less, and particularly preferably 6% or less. The range is preferably 1 to 15%, more preferably 1 to 10%, even more preferably 2 to 8%, and particularly preferably 3 to 6%. This range is more preferable because it is expected to have an effect against clogged pores, such as inhibiting keratin plug formation, and provides an excellent feel during use, such as a non-sticky feeling and a smooth feeling on the skin after use.

[0017] (Component (B): Polyhydric alcohol with an IOB value of 4.5 to 5.5)

[0018] The polyhydric alcohol having an IOB value of 4.5 to 5.5 (component (B)) used in the present invention is an alcohol having two or more hydroxyl groups and an IOB value of 4.5 to 5.5, in which the hydrogen atoms of a chain hydrocarbon are substituted with hydroxyl groups. The chain hydrocarbon includes both linear and branched chain hydrocarbons. Examples include glycerin (IOB value = 5.0) and sorbitol (IOB value = 5.0), and one or more of each may be selected and used as needed. In the present invention, from the viewpoint of the precipitation-inhibiting effect of component (A), polyhydric alcohols other than sugar alcohols are preferred, and glycerin (IOB value = 5.0) is particularly preferred.

[0019] The content of component (B) in the present invention is not particularly limited, but from the viewpoint of the effect of inhibiting the deposition of component (A), the lower limit in the aqueous composition is preferably 0.1% or more, more preferably 0.2% or more, and even more preferably 0.5% or more. The upper limit is also not particularly limited, but is preferably 10% or less, more preferably 8% or less. From the viewpoint of non-stickiness on the skin after application, it is more preferably 5% or less, and especially preferably 3% or less. The range is preferably 0.1 to 10%, more preferably 0.2 to 8%, even more preferably 0.5 to 5%, and especially preferably 0.5 to 3%. This range is more preferable because it provides an excellent effect of inhibiting the deposition of component (A) and provides excellent usability, such as non-stickiness and a smooth feeling on the skin after application.

[0020] (Component (C): Polyhydric alcohol with an IOB value of 1.5 to 3.5)

[0021] The component (C) used in the present invention, a polyhydric alcohol having an IOB value of 1.5 to 3.5, is an alcohol having two or more hydroxyl groups and an IOB value of 1.5 to 3.5, in which the hydrogen atoms of a chain hydrocarbon are substituted with hydroxyl groups. The chain hydrocarbon includes both linear and branched chain hydrocarbons. Examples include propylene glycol (1,2-propanediol) (IOB value = 3.3), dipropylene glycol (IOB value = 1.8), 1,3-propanediol (IOB value = 3.3), diglycerin (IOB value = 3.5), polyglycerin-3 (IOB value = 3.0), 1,3-butylene glycol (IOB value = 2.5), 1,2-pentanediol (IOB value = 2.0), isoprene glycol (IOB value = 2.2), and PEG-8 (MW400) (IOB value = 2.3), and one or more of each can be selected and used as needed. In the present invention, from the viewpoint of the precipitation-inhibiting effect of component (A), polyhydric alcohols other than sugar alcohols are preferred, and at least one selected from propylene glycol (IOB value = 3.3), dipropylene glycol (IOB value = 1.8), diglycerin (IOB value = 3.5), and 1,3-butylene glycol (IOB value = 2.5) is more preferred, and at least one selected from dipropylene glycol (IOB value = 1.8) and 1,3-butylene glycol (IOB value = 2.5) is particularly preferred.

[0022] In the present invention, from the viewpoint of the effect of inhibiting precipitation of component (A), component (C) preferably has an IOB value of 1.5 to 3.0, more preferably an IOB value of 1.5 to 2.5, and even more preferably an IOB value of 1.8 to 2.5.

[0023] In the present invention, from the viewpoint of the effect of inhibiting precipitation of component (A), component (C) is preferably two or more types. Specifically, component (C) is more preferably two or more types selected from propylene glycol, dipropylene glycol, 1,3-propanediol, diglycerin, polyglycerin-3, and 1,3-butylene glycol, even more preferably two or more types selected from propylene glycol, dipropylene glycol, 1,3-propanediol, diglycerin, and 1,3-butylene glycol, and dipropylene glycol and 1,3-butylene glycol are particularly preferred.

[0024] The content of component (C) in the present invention is not particularly limited, but from the viewpoint of the effect of inhibiting precipitation of component (A), the lower limit in the aqueous composition is preferably 1% or more, more preferably 2% or more, and even more preferably 4% or more. The upper limit is also not particularly limited, but is preferably 30% or less, more preferably 25% or less. From the viewpoint of non-stickiness on the skin after use, 20% or less is more preferable, and 15% or less is particularly preferable. The range is preferably 1 to 30%, more preferably 2 to 25%, even more preferably 4 to 20%, and especially preferably 4 to 15%. This range is more preferable because it provides an excellent effect of inhibiting precipitation of component (A) and provides excellent usability, such as non-stickiness and a smooth feeling on the skin after use.

[0025] In the present invention, from the viewpoint of more suitably suppressing the precipitation of component (A), the total content (B)+(C) of components (B) and (C) in the aqueous composition is preferably at least 3% as a lower limit, more preferably at least 5%. The upper limit is preferably at most 30%, more preferably at most 25%, even more preferably at most 22%, even more preferably at most 20%, and particularly preferably at most 15%. The range is preferably 3 to 30%, more preferably at most 5 to 25%, even more preferably at most 5 to 22%, even more preferably at most 5 to 20%, and particularly preferably at most 5 to 15%. This range is more preferable because it provides excellent sensations during use, such as a lack of stickiness and a smooth feeling on the skin after application.

[0026] In the present invention, from the viewpoint of more suitably suppressing the precipitation of component (A), the mass ratio (A) / [(B)+(C)] of component (A) to the total content of components (B) and (C) is preferably at least 0.01, more preferably at least 0.05, and even more preferably at least 0.1. The upper limit is preferably at most 1, more preferably at most 0.8, even more preferably at most 0.6, and particularly preferably at most 0.5. The range is preferably from 0.01 to 1, more preferably from 0.05 to 0.8, even more preferably from 0.1 to 0.6, and particularly preferably from 0.1 to 0.5. Setting the range within this range is more preferable because it provides excellent sensations during use, such as a lack of stickiness and a smooth feeling on the skin after application.

[0027] (Component (D): Nonionic surfactant)

[0028] In the present invention, further inclusion of component (D) a nonionic surfactant makes it possible to improve the effect against clogged pores due to the removal of keratin plugs, and is more preferable because it provides a non-sticky, smooth feeling to the skin after use. The nonionic surfactant (D) used in the present invention is not particularly limited as long as it is one commonly used in cosmetics. Specific examples include polyglycerin fatty acid esters, sucrose fatty acid esters, polyoxyalkylene sorbitan fatty acid esters, sorbitan fatty acid esters, polyoxyalkylene sorbit fatty acid esters, polyoxyalkylene glycol fatty acid esters, polyoxyalkylene glycerin fatty acid esters, polyoxyalkylene alkyl ethers, polyoxyethylene hydrogenated castor oil, fatty acid esters, polyoxyalkylene fatty acid alkanolamides, and silicone surfactants.

[0029] In the present invention, component (D) preferably contains at least one nonionic surfactant having an HLB of not more than 7. Here, HLB is a value that represents the balance between the hydrophilicity and lipophilicity of a surfactant, and in the present invention, specifically, it can be calculated by the Kawakami formula below. HLB = 7 + 11.7 log(Mw / Mo) (Here, Mw represents the molecular weight of the hydrophilic base, and Mo represents the molecular weight of the new oil base.)

[0030] Nonionic surfactants with an HLB of 7 or less include polyglycerin fatty acid esters, sorbitan fatty acid esters, and silicone surfactants. Silicone surfactants may be graft copolymers with organopolysiloxane groups as the main chain and hydrophilic groups as the side chains, or may contain linear block copolymers or crosslinked polymers in which organopolysiloxane groups and hydrophilic groups are alternately bonded. Examples of surfactants with linear organopolysiloxane groups as the main chain and polyoxyalkylene groups as the side chains include polyoxyalkylene-modified organopolysiloxanes and polyoxyalkylene-alkyl co-modified organopolysiloxanes. Examples of surfactants with hydrophilic groups include polyether-modified silicones with polyether chains and polyglycerin-modified silicones with polyglycerin chains.

[0031] More specifically, polyglycerin fatty acid esters such as diglyceryl monostearate (HLB 5.0), diglyceryl monooleate (HLB 6.5), diglyceryl dioleate (HLB 7.0), diglyceryl monoisostearate (HLB 5.5), tetraglyceryl monostearate (HLB 6.0), tetraglyceryl monooleate (HLB 6.0), and hexaglyceryl tristearate (HLB 2.5); sorbitan fatty acid esters such as sorbitan monostearate (HLB 4.7), sorbitan sesquistearate (HLB 4.2), sorbitan sesquiisostearate (HLB 4.0), and sorbitan sesquioleate (HLB 3.7); polyoxyethylene-methylpolysiloxane copolymers (for example, cosmetic ingredient list name: PEG-10 dimethicone ( Examples include polyether-modified silicones such as methylpolysiloxane-cetylmethylpolysiloxane-poly(oxyethylene-oxypropylene)methylpolysiloxane copolymer (HLB 5.0), poly(oxyethylene-oxypropylene)methylpolysiloxane copolymer (Cosmetic All Ingredients Name: PEG / PPG-20 / 22 Butyl Ether Dimethicone) (HLB 7.0), PEG-9 Polydimethylsiloxyethyl Dimethicone (HLB 4.0), and Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone (HLB 3.0), and block copolymer-type silicone surfactants such as poly(oxyethylene-oxypropylene)-butylene-methylpolysiloxane copolymer (HLB 6.0). One or more of these can be used.

[0032] Among the nonionic surfactants having an HLB of 7 or less that can be used in the present invention, silicone surfactants are preferred, and polyether-modified silicones having polyoxyethylene groups are more preferred, from the viewpoint of more suitably exhibiting effects against clogged pores, non-stickiness on the skin after use, and a smooth feeling when used. Commercially available examples of such silicone surfactants include KF-6017 (manufactured by Shin-Etsu Chemical Co., Ltd.), 5200 Formulation Aid (manufactured by Dow Corning Toray Co., Ltd.), ABIL EM97S (manufactured by EVONIC GOLDSCHMIDT), KF-6028, KF-6038, KF-6012 (all manufactured by Shin-Etsu Chemical Co., Ltd.), ABIL EM90 (manufactured by EVONIC GOLDSCHMIDT), KF-6105 (manufactured by Shin-Etsu Chemical Co., Ltd.), FZ-2250, FZ-2233 (all manufactured by Dow Corning Toray Co., Ltd.), and SILWET 236-L (manufactured by Nippon Unicar Co., Ltd.).

[0033] In the present invention, from the viewpoint of more suitably exhibiting the effect of inhibiting precipitation of component (A) while also exhibiting the effect against clogged pores, non-stickiness on the skin after use, and a smooth feeling when used, component (D) is preferably at least one selected from silicone surfactants and polyoxyalkylene fatty acid alkanolamides, and more preferably silicone surfactants and polyoxyalkylene fatty acid alkanolamides.

[0034] Polyoxyalkylene fatty acid alkanolamide is obtained by addition polymerization of alkylene oxide to fatty acid alkanolamide, which is a condensation product of a fatty acid and an alkanolamine. The alkylene in "polyoxyalkylene" is not particularly limited, but is preferably, for example, an alkylene having 2 to 4 carbon atoms, and specific examples include polyoxyethylene, polyoxypropylene, polyoxybutylene, etc. The average number of moles added of polyoxyalkylene is not particularly limited, but is preferably 0.1 to 12 moles. The "fatty acid" is not particularly limited, but for example, those having 8 to 22 carbon atoms are preferred, and these may be one type or a mixture of two or more types, and coconut oil fatty acids can also be used. The "alkanolamine" is not particularly limited, but is preferably one having 2 to 4 carbon atoms, specifically, monoisopropanolamine, monoethanolamine, diethanolamine, etc. Polyoxyalkylene fatty acid alkanolamides can be obtained by combining these, but are preferably one or more selected from polyoxypropylene coconut oil fatty acid monoisopropanolamide and polyoxyethylene coconut oil fatty acid monoethanolamide, with polyoxyethylene coconut oil fatty acid monoethanolamide being more preferred. The average number of moles of polyoxyethylene added is also not particularly limited, and can be 1 to 12 moles per molecule, but is preferably 2 to 8 moles, with polyoxyethylene coconut oil fatty acid monoethanolamide (PEG-3 cocamide) and polyoxyethylene coconut oil fatty acid monoethanolamide (PEG-6 cocamide) being more preferred. Commercially available products include Amizet 2C and Amizet 5C (both manufactured by Kawaken Fine Chemicals Co., Ltd.).

[0035] The content of component (D) in the present invention is not particularly limited, but from the viewpoints of the effect on clogged pores and the feeling of use, such as a non-sticky feeling on the skin after use and a smooth feeling, the lower limit in the aqueous composition is preferably 0.1% or more, more preferably 0.2% or more, even more preferably 0.3% or more, and particularly preferably 0.5% or more. The upper limit is preferably 5% or less, more preferably 4% or less, even more preferably 3% or less, and from the viewpoint of a non-sticky feeling on the skin after use, even more preferably 2% or less. The range is preferably 0.1 to 5%, more preferably 0.2 to 4%, even more preferably 0.3 to 3%, and even more preferably 0.5 to 2%.

[0036] As described above, in the present invention, component (D) is more preferably a silicone surfactant and a polyoxyalkylene fatty acid alkanolamide. In this case, the mass ratio of the silicone surfactant to the polyoxyalkylene fatty acid alkanolamide (silicone surfactant / polyoxyalkylene fatty acid alkanolamide) is preferably 0.5 to 5, more preferably 1 to 3. This range is more preferable because it allows the component (A) to exhibit its precipitation-inhibiting effect while more suitably exhibiting the anti-pore clogging effect and providing a smooth, non-sticky feel on the skin after use.

[0037] In the present invention, the mass ratio (A) / (D) of component (A) to component (D) is not particularly limited, but the lower limit is preferably 0.5 or more, more preferably 1 or more, and even more preferably 2 or more. The upper limit is preferably 30 or less, more preferably 20 or less, even more preferably 15 or less, and particularly preferably 10 or less. The range is preferably 0.5 to 30, more preferably 1 to 20, even more preferably 2 to 15, and particularly preferably 2 to 10. This range is more preferable because it exhibits the effect of inhibiting precipitation of component (A) while also providing excellent sensations in use, such as non-stickiness and a smooth feeling on the skin after use.

[0038] (Component (E): Alkylene oxide derivative represented by general formula (I))

[0039] In the present invention, it is more preferable to further contain component (E) an alkylene oxide derivative, as this improves the non-stickiness and smooth feeling on the skin after application. The alkylene oxide derivative of component (E) used in the present invention is represented by general formula (1). Z-{O-(EO)a-(PO)b-(BO)cH}n (1) (In formula (1), n ​​is an integer of 1 to 4, Z is a residue obtained by removing n hydroxy groups from a hydrogen atom or a polyhydric alcohol having 2 to 4 hydroxyl groups, EO is an oxyethylene group, PO is an oxypropylene group, and BO is an oxybutylene group. a, b, and c are the average numbers of moles of EO, PO, and BO added, respectively, and are values ​​of 0≦a≦50, 0≦b≦50, and 0≦c≦5. a, b, and c are not all 0, and when a and b are not 0, the mass ratio (PO / EO) is 1 / 5 to 5 / 1. EO and PO may be added randomly or in blocks, and when n is 2 or greater, multiple a's, b's, and c's may be the same or different, and when Z is a hydrogen atom, n is 1.)

[0040] In general formula (1), Z is a hydrogen atom or a residue obtained by removing n hydroxy groups from a polyhydric alcohol having 2 to 4 hydroxy groups. In the present invention, Z is preferably a residue obtained by removing n hydroxy groups from a polyhydric alcohol having 2 to 4 hydroxy groups. Hydrocarbons containing hydroxy groups are preferred as polyhydric alcohols, and saturated hydrocarbons containing hydroxy groups are more preferred. For example, when n is 2, ethylene glycol, propanediol, and butylene glycol are preferred; when n is 3, glycerin and trimethylolpropane are preferred; and when n is 4, erythritol, pentaerythritol, sorbitan, alkyl glycosides, and diglycerin are preferred; and mixtures of these can also be used. Among these, glycerin, diglycerin, and methyl glucoside are preferred as polyhydric alcohols; glycerin and diglycerin are more preferred, and glycerin is particularly preferred.

[0041] In general formula (1), EO is an oxyethylene group, PO is an oxypropylene group, and BO is an oxybutylene group. In general formula (1), a, b, and c are the average numbers of moles of EO, PO, and BO added, respectively, and are values ​​of 0≦a≦50, 0≦b≦50, and 0≦c≦5, and a, b, and c will never all be 0. When a=0, it is preferable that b=1 to 20 and c=0, and it is more preferable that b=1 to 10 and c=0. When b=0, a=1 to 30 and c=0 are preferred, and a=5 to 30 and c=0 are more preferred. When neither a nor b is 0, it is preferable that a and b are 1 to 10 and c=0 to 5, and it is more preferable that a and b are 1 to 8 and c=1 to 3. In general formula (1), when neither a nor b is 0, the mass ratio of PO to EO (PO / EO) is 1 / 5 to 5 / 1, and the addition form of PO and EO may be random or block. The sum of the average number of moles of PO and EO added (a+b) is preferably in the range of 1 to 30. If (a+b) is less than 1, the non-stickiness of the skin after application may not be excellent.

[0042] More specifically, the component (E) in which Z is a group derived from glycerin includes polyoxybutylene polyoxyethylene polyoxypropylene glyceryl ether (3B Examples of polyoxyethylene glycerin (26E.O.) (cosmetics labeling name: glycerin), polyoxypropylene glyceryl ether (cosmetics labeling name: PPG-16 glyceryl ether), polyoxyethylene glycerin (26E.O.) (cosmetics labeling name: glycereth-26), etc., and examples of polyoxyethylene methyl glucosides in which Z is a group derived from a methyl glucoside include polyoxypropylene methyl glucoside (cosmetics labeling name: PPG-10 methyl glucose, PPG-20 methyl glucose), polyoxyethylene methyl glucoside (cosmetics labeling name: glycerin), polyoxypropylene methyl glucoside (cosmetics labeling name: glycerin ...ethylene methyl glucoside (cosmetics labeling name: glycerin), polyoxyethylene methyl glucoside (cosmetics labeling name: glycerin), polyoxyethylene methyl Examples of copolymers in which Z is a hydrogen atom include polypropylene glycol (cosmetics labeling names: PPG-7, PPG-34) and polyoxyethylene polypropylene glycol (cosmetics labeling names: PEG / PPG-150 / 35 copolymer, PEG / PPG-160 / 30 copolymer), and examples of copolymers in which Z is a group derived from diglycerin include polyoxypropylene diglyceryl ether (cosmetics labeling names: PPG-14 polyglyceryl-2 ether, PPG-9 diglyceryl). In the present invention, from the viewpoint of the feel upon use, such as non-stickiness on the skin after use and a smooth feeling on the skin after use, one or more selected from PEG / PPG / polybutylene glycol-8 / 5 / 3 glycerin, glycereth-26, PPG-10 methyl glucose, PPG-20 methyl glucose, methyl gluceth-10, methyl gluceth-20 and PPG-9 diglyceryl are preferred, and one or more selected from PEG / PPG / polybutylene glycol-8 / 5 / 3 glycerin, glycereth-26 and PPG-9 diglyceryl are more preferred.

[0043] The content of component (E) in the present invention is not particularly limited, but from the viewpoint of non-stickiness on the skin after use, the lower limit in the aqueous composition is preferably 0.1% or more, and more preferably 0.2% or more. The upper limit is preferably 10% or less, more preferably 8% or less, and from the viewpoint of smooth skin after use, it is even more preferably 5% or less, and even more preferably 3% or less. The range is preferably 0.1 to 10%, more preferably 0.2 to 8%, even more preferably 0.2 to 5%, and particularly preferably 0.2 to 3%. This range is more preferable because it exhibits the effect of inhibiting precipitation of component (A) while more suitably exhibiting a feel during use such as non-stickiness and a smooth skin after use.

[0044] In the present invention, the mass ratio (A) / (E) of component (A) to component (E) is not particularly limited, but the lower limit is preferably 0.1 or more, more preferably 0.3 or more, even more preferably 0.5 or more, and particularly preferably 1 or more. The upper limit is preferably 30 or less, more preferably 20 or less, even more preferably 15 or less, and particularly preferably 10 or less. The range is preferably 0.1 to 30, more preferably 0.3 to 20, even more preferably 0.5 to 15, and particularly preferably 1 to 10. This range is more preferable because it exhibits the effect of inhibiting precipitation of component (A) while also providing excellent sensation of use, such as non-stickiness and a smooth feeling on the skin after use.

[0045] The viscosity of the aqueous composition of the present invention at 30°C is not particularly limited, but the lower limit is preferably 100 mPa·s or more, more preferably 500 mPa·s or more, even more preferably 1,000 mPa·s or more, and particularly preferably 2,000 mPa·s or more. The upper limit is preferably 20,000 mPa·s or less, more preferably 15,000 mPa·s or less, and even more preferably 11,000 mPa·s or less. This range is preferable because it facilitates wiping, effectively prevents clogged pores, and leaves the skin feeling smooth and non-sticky. Here, the viscosity in the present invention refers to the value obtained by reading the measured value after leaving the composition in a 30°C thermostatic bath for 24 hours and rotating the rotor at a speed of 6 revolutions per minute using a single-cylinder rotational viscometer (manufactured by Shibaura Systems Co., Ltd.) and multiplying the measured value by the respective multipliers.

[0046] The pH of the aqueous composition of the present invention is not particularly limited, but is preferably 0.01 to 0.01% by weight at 25°C. is preferably in the range of 4.0 to 8.0.

[0047] In addition to the above components (A) to (E), the aqueous composition of the present invention may contain optional components contained in ordinary cosmetics and the like, to the extent that the effects of the present invention are not impaired, such as water, oils, powders, water-soluble polymers, film-forming agents, surfactants, lower alcohols, gelling agents, organically modified clay minerals, resins, colorants, UV absorbers, preservatives, antibacterial agents, fragrances, antioxidants, pH adjusters, chelating agents, vitamins, amino acids, cosmetic ingredients, etc. In the aqueous composition of the present invention, the precipitation-inhibiting effect of component (A) is more suitably exhibited, so the proportion of aqueous components in the composition is preferably 60% or more, more preferably 70% or more, even more preferably 80% or more, and particularly preferably 90% or more.

[0048] In the present invention, the aqueous component refers to water or a liquid component that is compatible with water. Examples of liquid components that are compatible with water include polyhydric alcohols such as component (B) and component (C), lower alcohols such as ethanol, and alkylene oxide derivatives such as component (E), and one or more of these can be used as needed. In the present invention, the liquid component that is compatible with water is preferably at least one selected from polyhydric alcohols, lower alcohols, and alkylene oxide derivatives.

[0049] The aqueous composition of the present invention refers to a composition containing water, and typically contains 10% or more of water in the composition, preferably 20% or more, more preferably 30% or more, and even more preferably 50% or more. The upper limit is not particularly limited, but is preferably 90% or less. The water contained in the aqueous composition of the present invention may be any water that can be contained in cosmetics, quasi-drugs, pharmaceuticals, etc., such as purified water, hot spring water, deep sea water, tap water, distilled water, or steam-distilled water from plants, and one or more of these may be appropriately selected and used as needed. As long as the aqueous composition contains water as described above, it may be in a form emulsified with an emulsifier or the like.

[0050] A lower alcohol is an alcohol having one hydroxyl group, in which a hydrogen atom of a chain hydrocarbon having 2 to 5 carbon atoms is substituted with a hydroxyl group. The chain hydrocarbon includes linear and branched hydrocarbons. Examples include ethanol and isopropanol.

[0051] The surfactant may be an anionic surfactant, a cationic surfactant, or an amphoteric surfactant.

[0052] Examples of anionic surfactants include fatty acid soaps (e.g., sodium laurate, sodium palmitate, etc.); higher alkyl sulfates (e.g., sodium lauryl sulfate, potassium lauryl sulfate, etc.); alkyl ether sulfates (e.g., POE-lauryl triethanolamine sulfate, POE-lauryl sodium sulfate, etc.); N-acyl sarcosinates (e.g., sodium lauroyl sarcosinate, etc.); higher fatty acid amide sulfonates (e.g., sodium N-myristoyl-N-methyl taurate, sodium coconut oil fatty acid methyl taurate, sodium stearoyl methyl taurate, sodium lauryl methyl taurate, etc.); sulfosuccinates (e.g., sodium di-2-ethylhexyl sulfosuccinate, sodium monolauroyl monoethanolamide polyoxyethylene sulfosuccinate, sodium lauryl polypropylene glycol ... alkylbenzenesulfonates (e.g., sodium linear dodecylbenzenesulfonate, triethanolamine linear dodecylbenzenesulfonate, linear dodecylbenzenesulfonic acid, etc.); higher fatty acid ester sulfate salts (e.g., sodium hydrogenated coconut oil fatty acid glycerin sulfate, etc.); N-acylglutamates (e.g., monosodium N-lauroylglutamate, disodium N-stearoylglutamate, monosodium N-myristoyl-L-glutamate, etc.); POE-alkyl ether carboxylic acids; POE-alkyl allyl ether carboxylates; α-olefin sulfonates; higher fatty acid ester sulfonates; secondary alcohol sulfate salts; higher fatty acid alkylolamide sulfate salts; sodium lauroylmonoethanolamide succinate; ditriethanolamine N-palmitoyl aspartate; sodium caseinate, etc.

[0053] Examples of cationic surfactants include alkyltrimethylammonium salts (e.g., stearyltrimethylammonium chloride, lauryltrimethylammonium chloride, etc.); alkylpyridinium salts (e.g., cetylpyridinium chloride, etc.); dialkyldimethylammonium chloride salts (e.g., distearyldimethylammonium chloride, etc.); poly(N,N'-dimethyl-3,5-methylenepiperidinium chloride); alkyl quaternary ammonium salts; alkyldimethylbenzylammonium salts; alkylisoquinolinium salts; dialkylmorphonium salts; POE-alkylamines; alkylamine salts; polyamine fatty acid derivatives; amyl alcohol fatty acid derivatives; benzalkonium chloride; benzethonium chloride, etc.

[0054] Examples of amphoteric surfactants include imidazoline-based amphoteric surfactants (e.g., 2-undecyl-N,N,N-(hydroxyethylcarboxymethyl)-2-imidazoline sodium, 2-cocoyl-2-imidazolinium hydroxide-1-carboxyethyloxy disodium salt, etc.); betaine-based surfactants (e.g., 2-heptadecyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine, lauryldimethylaminoacetic acid betaine, alkyl betaine, amido betaine, sulfobetaine, etc.); and phospholipids (e.g., lecithin, hydrogenated lecithin, etc.). Lecithin can be derived from soybeans, eggs, etc.

[0055] As the oil agent, oily components such as higher alcohols, hydrocarbon oils, ester oils, fats and oils, silicone oils, etc., can be used. For example, higher alcohols such as lauryl alcohol, myristyl alcohol, palmityl alcohol, stearyl alcohol, behenyl alcohol, hexadecyl alcohol, oleyl alcohol, isostearyl alcohol, hexyldodecanol, octyldodecanol, cetostearyl alcohol, 2-decyltetradecynol, cholesterol, phytosterol, sitosterol, lanosterol, monostearyl glycerin ether (batyl alcohol), fatty acids such as isostearic acid and oleic acid, ozokerite, etc. Hydrocarbons such as cereals, squalane, squalene, ceresin, paraffin, paraffin wax, liquid paraffin, pristane, polyisobutylene, microcrystalline wax, and petrolatum, diisobutyl adipate, 2-hexyldecyl adipate, di-2-heptylundecyl adipate, N-alkyl glycol monoisostearate, isocetyl isostearate, trimethylolpropane triisostearate, cetyl tri-2-ethylhexanoate, ethylene glycol di-2-ethylhexanoate, and 2-ethylhexanoic acid. Cetyl, trimethylolpropane tri-2-ethylhexanoate, pentaerythritol tetra-2-ethylhexanoate, cetyl octanoate, octyldodecyl gum ester, oleyl oleate, octyldodecyl oleate, decyl oleate, neopentyl glycol dicaprate, triethyl citrate, 2-ethylhexyl succinate, isocetyl stearate, butyl stearate, diisopropyl sebacate, di-2-ethylhexyl sebacate, cetyl lactate, myristyl lactate, isopropyl palmitate, palmitic ester oils such as 2-ethylhexyl myristate, 2-hexyldecyl palmitate, 2-heptylundecyl palmitate, cholesteryl 12-hydroxystearate, dipentaerythritol fatty acid esters, isopropyl myristate, octyldodecyl myristate, 2-hexyldecyl myristate, myristyl myristate, hexyldecyl dimethyloctanoate, ethyl laurate, hexyl laurate, diisostearyl malate, and glyceryl tri-2-ethylhexanoate, beeswax, carnauba wax, candelilla wax,Examples of suitable oils include waxes such as spermaceti, vegetable oils such as palm oil, palm kernel oil, olive oil, safflower oil, soybean oil, and cottonseed oil, animal oils such as beef tallow, beef leg fat, beef bone fat, hardened beef tallow, hardened oil, turtle oil, lard, horse fat, mink oil, liver oil, and egg yolk oil, lanolin derivatives such as lanolin, liquid lanolin, reduced lanolin, lanolin alcohol, hard lanolin, lanolin acetate, and lanolin fatty acid isopropyl, and silicone oils such as methylpolysiloxane (dimethicone), methylphenylpolysiloxane, decamethylcyclopentasiloxane, and octamethylcyclotetrasiloxane. In the present invention, in order to optimally exhibit the effect of suppressing precipitation of component (A), the content of the oil in the aqueous composition is preferably 1% or less, more preferably 0.5% or less, and even more preferably 0.1% or less.

[0056] As the powder, any powder used in ordinary cosmetics can be used regardless of its shape (spherical, acicular, plate-like, etc.), particle size (aerosol, fine particles, pigment-grade, etc.), or particle structure (porous, non-porous, etc.). For example, inorganic powders include magnesium oxide, barium sulfate, calcium sulfate, magnesium sulfate, calcium carbonate, magnesium carbonate, talc, synthetic mica, mica, kaolin, sericite, muscovite, synthetic mica, phlogopite, lepidolite, biotite, lepidolite, silicic acid, silicic anhydride, aluminum silicate, magnesium silicate, aluminum silicate, and the like. Calcium magnesium, calcium silicate, barium silicate, strontium silicate, metal tungstate, hydroxyapatite, vermiculite, higilite, montmorillonite, zeolite, ceramic powder, dibasic calcium phosphate, alumina, aluminum hydroxide, boron nitride, boron nitride, etc. Organic powders include polyamide powder, polyester powder, polyethylene powder, polypropylene powder, polystyrene powder, polyurethane powder, benzoguanamine powder, polymethylbenzoguanamine powder, tetrafluoroethylene powder, polymethyl methacrylate powder, cellulose powder, silk powder, nylon powder, nylon 12 powder, nylon 6 powder, styrene-acrylic acid copolymer powder, divinylbenzene-styrene copolymer powder, vinyl resin powder, urea resin powder, phenolic resin powder, fluororesin powder, silicon resin powder, acrylic resin powder, melamine resin powder, epoxy resin powder, polycarbonate resin powder, microcrystalline fiber powder, lauroyl lysine, etc. Colored pigments include Inorganic red pigments such as iron oxide, iron hydroxide, and iron titanate, inorganic brown pigments such as gamma-iron oxide, inorganic yellow pigments such as yellow iron oxide and ochre, inorganic black pigments such as black iron oxide and carbon black, inorganic purple pigments such as manganese violet and cobalt violet, inorganic green pigments such as chromium hydroxide, chromium oxide, cobalt oxide, and cobalt titanate, inorganic blue pigments such as iron blue and ultramarine, lakes of tar-based pigments, lakes of natural pigments, and composite powders of these powders; pearl pigments include titanium dioxide-coated mica, titanium dioxide-coated mica, bismuth oxychloride,Titanium oxide-coated bismuth oxychloride, titanium oxide-coated talc, fish scale foil, titanium oxide-coated colored mica, etc. Metal powder pigments include aluminum powder, copper powder, stainless steel powder, etc. Tar dyes include Red No. 3, Red No. 104, Red No. 106, Red No. 201, Red No. 202, Red No. 204, Red No. 205, Red No. 220, Red No. 226, Red No. 227, Red No. 228, Red No. 230, Red No. 401, Red No. 505, Yellow No. 4, Yellow No. 5, Yellow 202 No. 203, Yellow No. 204, Yellow No. 401, Blue No. 1, Blue No. 2, Blue No. 201, Blue No. 404, Green No. 3, Green No. 201, Green No. 204, Green No. 205, Orange No. 201, Orange No. 203, Orange No. 204, Orange No. 206, Orange No. 207, etc. Natural pigments include powders selected from carminic acid, laccaic acid, carthamine, brazilian, crocin, etc., and may be composites of these powders or powders surface-treated with oils, silicones, fluorine compounds, etc.

[0057] Examples of water-soluble polymers include mucopolysaccharides selected from chondroitin sulfate, hyaluronic acid, mucin, dermatan sulfate, heparin, and keratan sulfate, and salts thereof; plant-based polymers such as gum arabic, tragacanth, galactan, carob gum, guar gum, karaya gum, carrageenan, pectin, agar, quince seed, algae colloid, toranth gum, locust bean gum, and galactomannan; microbial polymers such as xanthan gum, dextran, succinoglucan, and pullulan; starch-based polymers such as starch, carboxymethyl starch, and methylhydroxypropyl starch; methylcellulose, ethylcellulose, and the like. Examples of suitable anionic polymers include cellulose, methylhydroxypropylcellulose, carboxymethylcellulose, hydroxymethylcellulose, hydroxypropylcellulose, nitrocellulose, sodium cellulose sulfate, sodium carboxymethylcellulose, crystalline cellulose, and cellulose; alginate polymers, such as sodium alginate and propylene glycol alginate; vinyl polymers, such as polyvinyl methyl ether; polyoxyethylene polymers, polyoxyethylene-polyoxypropylene copolymer polymers; and inorganic water-soluble polymers, such as bentonite, laponite, and hectorite. Examples of suitable anionic polymers include carboxyvinyl polymers, acrylic acid-alkyl methacrylate copolymers, sodium acrylate-sodium acryloyldimethyltaurate copolymers, hydroxyethyl acrylate-sodium acryloyldimethyltaurate copolymers, (acrylates / beheneth-25 methacrylate) copolymers, acrylic acid-ethyl acrylate-N-tert-butylacrylamide copolymers, acrylic resin alkanolamines, vinyl methyl ether-ethyl maleate copolymers, vinyl methyl ether-butyl maleate copolymers, and vinyl acetate-crotonic acid copolymers.Examples of amphoteric polymers include N-methacryloylethyl N,N-dimethylammonium·α-N-methylcarboxybetaine·alkyl methacrylate copolymer, hydroxypropyl acrylate·butylaminoethyl methacrylate·octyl acrylate copolymer, acrylic acid·dimethyldiallylammonium chloride·acrylamide copolymer, and dimethyldiallylammonium chloride·acrylic acid copolymer. Examples of cationic polymers include vinylpyrrolidone·N,N-dimethylaminoethyl methacrylate copolymer diethyl sulfate, diallyldimethylammonium chloride·hydroxyethylcellulose, glycidyltrimethylammonium chloride·hydroxyethylcellulose, dimethyldiallylammonium chloride polymer, and dimethyldiallylammonium chloride·acrylamide copolymer. Examples of nonionic polymers include polyvinylpyrrolidone, vinylpyrrolidone·vinyl acetate copolymer, polyvinyl alcohol, and polyurethane.

[0058] Examples of antibacterial agents include benzoic acid, sodium benzoate, salicylic acid, carbolic acid, sorbic acid, potassium sorbate, parachlormetacresol, hexachlorophene, benzalkonium chloride, chlorhexidine chloride, trichlorocarbanilide, photosensitizers, zinc bis(2-pyridylthio-1-oxide), isopropylmethylphenol, and glyceryl caprylate. Examples of preservatives include parahydroxybenzoic acid esters and phenoxyethanol.

[0059] Examples of vitamins include vitamin A and its derivatives, vitamin B and its derivatives, vitamin C and its derivatives, vitamin E and its derivatives, vitamin F such as linoleic acid and its derivatives, vitamin K such as phytonadione, menaquinone, menadione, and menadiol, vitamin P such as eriocitrin and hesperidin, biotin, carnitine, and ferulic acid.

[0060] The form of the aqueous composition of the present invention is not particularly limited, and examples thereof include liquid, gel, emulsion, cream, semi-solid, and solid forms, with liquid being preferred.

[0061] The formulation of the aqueous composition is not particularly limited, and examples thereof include aqueous, solubilized, oil-in-water, water-in-oil, water-in-oil-in-water, oil-in-water-in-oil, multi-layered, etc. In the present invention, compositions in which the external phase is aqueous are preferred, and specific examples thereof include aqueous, solubilized, and oil-in-water types.

[0062] The aqueous composition of the present invention may be used as a final formulation as is, or may be a final formulation in which the aqueous composition is a part of the final formulation and further mixed with other components. Examples of final formulations include cosmetics, topical skin preparations, and pharmaceutical preparations. In the present invention, the final formulation is preferably a cosmetic or topical skin preparation, from the viewpoint of easily exhibiting the effects of the aqueous composition, such as the effect of inhibiting precipitation of component (A), and also the non-sticky and smooth feeling of the skin after application. The content of the aqueous composition in the final formulation is not particularly limited, but is preferably 1 to 100% in the formulation.

[0063] When used as a cosmetic product, it is suitable, for example, as a lotion, emulsion, cream, serum, massage cosmetic, pack cosmetic, hand cream, body lotion, body cream, makeup cosmetic, cosmetic base cosmetic, eye cream, sunscreen, hair cream, hair wax, etc., and is preferably used as a skin care cosmetic in that the effect can be felt. Methods of use include application to hands, fingers, or cotton, impregnation of a sheet, etc., and direct spraying. In the present invention, wiping use is more preferred, in which the aqueous composition is moistened onto a cosmetic cotton or sheet, etc., and used to wipe the surface of the skin. When used as an external preparation for the skin, examples include external liquid preparations, external gel preparations, cream preparations, ointments, liniments, lotions, poultices, plasters, sprays, aerosols, etc. Methods of use can be the same as those for the above-mentioned cosmetics, with wiping use being more preferred.

[0064] Here, the wet material (impregnated material) used for wiping is not particularly limited, but is preferably one or more materials selected from cotton and sheets. The cotton pad is not particularly limited, and may be one that is commonly used for cosmetics, etc. Commercially available cotton pads are not particularly limited, and examples thereof include Kose Pure & Soft Cotton and Kose Facial Care Cotton.

[0065] The sheet base of the sheet is not particularly limited, but is preferably a woven fabric or a nonwoven fabric, and is preferably a nonwoven fabric from the viewpoints of usability, ease of processing, etc. Examples of the nonwoven fabric include spunbond nonwoven fabric, spunlace nonwoven fabric, thermal bond nonwoven fabric, needle punch nonwoven fabric, stitch bond nonwoven fabric, etc. The sheet substrate can also be embossed. The basis weight of the sheet substrate is not particularly limited, but from the viewpoint of wiping comfort, it is preferably 30 to 90 g / m 2 is preferable, and 35 to 80 g / m 2 is more preferred.

[0066] The fibers constituting the woven fabric or nonwoven fabric are not particularly limited, and examples thereof include natural fibers, synthetic fibers, and semi-natural fibers. Examples of the natural fibers include cotton, pulp, silk, cellulose, hemp, linter, and kabab. Examples of the semi-natural fibers include rayon and acetate. Examples of the synthetic fibers include nylon fibers, polypropylene fibers, polyethylene fibers, polyethylene terephthalate fibers, polybutylene terephthalate fibers, and acrylic fibers.

[0067] The sheet substrate can be produced by a known production method depending on the type of woven fabric or nonwoven fabric.

[0068] In the present invention, the amount of the aqueous composition of the present invention to be wetted relative to the cotton or sheet is not particularly limited, but is preferably 0.1 to 9.0 parts by mass, more preferably 0.5 to 7.0 parts by mass, even more preferably 1.0 to 7.0 parts by mass, and particularly preferably 1.0 to 5.0 parts by mass, of the aqueous composition of the present invention relative to 1.0 part by mass of the cotton or sheet substrate.

[0069] The cosmetic composition for wipe-off use may be pre-filled in a container and sold as a product, and examples of the container include a bag (packaging bag) and a box-shaped container. The material of the container is not particularly limited, but examples thereof include resins such as polyethylene terephthalate (PET), polyethylene (PE), and polypropylene (PP), and metals such as aluminum.

[0070] The method for producing the aqueous composition of the present invention is not particularly limited, and the composition can be prepared by a conventional method. For example, the composition can be obtained by dissolving or dispersing the above-mentioned components (A) to (E) and, if necessary, the above-mentioned optional components in water.

[0071] In another aspect of the present invention, the composition can be used as component (A) a composition for inhibiting the precipitation of oligosaccharides, which contains as active ingredients component (B) a polyhydric alcohol having an IOB value of 4.5 to 5.5 and component (C) a polyhydric alcohol having an IOB value of 1.5 to 3.5.

[0072] In the description of the above-mentioned precipitation-inhibiting composition, explanations of the components (A) to (E), their respective contents, their respective content mass ratios, production methods, respective configurations, respective methods, respective terms, etc. will be omitted as appropriate, but the explanations for the aqueous composition described above also apply to this composition and can be adopted as appropriate.

[0073] In addition, as another aspect of the present invention, the present invention can be used as a method for inhibiting the precipitation of component (A) oligosaccharides (method for inhibiting the precipitation of component (A) oligosaccharides) using component (B) a polyhydric alcohol having an IOB value of 4.5 to 5.5 and component (C) a polyhydric alcohol having an IOB value of 1.5 to 3.5.

[0074] In the description of the above-mentioned method for inhibiting precipitation, explanations of the components (A) to (E), their respective contents, their respective content mass ratios, production methods, respective configurations, respective methods, respective terms, etc. will be omitted as appropriate, but the explanations for the aqueous composition described above also apply to this method and can be adopted as appropriate.

[0075] In another aspect of the present invention, the component (B) can be used as an agent for inhibiting precipitation of oligosaccharides, which contains as active ingredients a polyhydric alcohol having an IOB value of 4.5 to 5.5 and a polyhydric alcohol having an IOB value of 1.5 to 3.5.

[0076] In the description of the above-mentioned precipitation inhibitor, explanations of the components (A) to (E), their respective contents, their respective content mass ratios, production methods, respective configurations, respective methods, respective terms, etc. will be omitted as appropriate, but the explanations for the aqueous composition described above also apply to this agent and can be adopted as appropriate.

[0077] The present invention can also employ the following configuration. <1> The following components (A) to (C): (A) Oligosaccharides 1% by mass or more (B) Polyhydric alcohols with an IOB value of 4.5 to 5.5 (C) Polyhydric alcohols with an IOB value of 1.5 to 3.5 The aqueous composition comprises: <2> The component (A) is trehalose. <1> The aqueous composition according to claim 1. <3> the mass ratio (A) / [(B)+(C)] of the content of the component (A) to the total content of the component (B) and the component (C) is 0.01 to 1; <1> or <2> The aqueous composition according to claim 1. <4> The total content (B)+(C) of the component (B) and the component (C) is 3 to 30 mass %. <1> ~ <3> The aqueous composition is any one of the above. <5> The content of the component (A) is 3% by mass or more. <1> ~ <4> The aqueous composition is any one of the above. <6> The composition further contains a component (D) a nonionic surfactant. <1> ~ <5> The aqueous composition is any one of the above. <7> The component (D) is at least one selected from the group consisting of a silicone surfactant and a polyoxyalkylene fatty acid alkanolamide. <6> The aqueous composition according to claim 1. <8> The composition further contains component (E) an alkylene oxide derivative represented by general formula (1): <1> ~ <7> The aqueous composition is any one of the above. Z-{O-(EO)a-(PO)b-(BO)cH}n (1) (In formula (1), n ​​is an integer of 1 to 4, Z is a residue obtained by removing n hydroxy groups from a hydrogen atom or a polyhydric alcohol having 2 to 4 hydroxyl groups, EO is an oxyethylene group, PO is an oxypropylene group, and BO is an oxybutylene group. a, b, and c are the average numbers of moles of EO, PO, and BO added, respectively, and are values ​​of 0≦a≦50, 0≦b≦50, and 0≦c≦5. a, b, and c are not all 0, and when a and b are not 0, the mass ratio (PO / EO) is 1 / 5 to 5 / 1. EO and PO may be added randomly or in blocks, and when n is 2 or greater, multiple a's, b's, and c's may be the same or different, and when Z is a hydrogen atom, n is 1.) <9> The aforementioned <1> ~ <8> The present invention relates to a cosmetic or topical skin preparation containing the aqueous composition according to any one of the above. <10> The above-mentioned cosmetic or topical skin preparation. <1> ~ <8> The aqueous composition is any one of the above. <11> The above-mentioned product is for wiping. <9> or <10> The cosmetic or topical skin preparation according to the present invention is a cosmetic or topical skin preparation according to the present invention. <12> This method uses component (B) a polyhydric alcohol having an IOB value of 4.5 to 5.5 and component (C) a polyhydric alcohol having an IOB value of 1.5 to 3.5 to suppress precipitation of component (A) oligosaccharides. <13> The composition for inhibiting precipitation of oligosaccharides (Component (A)) contains, as active ingredients, component (B) a polyhydric alcohol having an IOB value of 4.5 to 5.5 and component (C) a polyhydric alcohol having an IOB value of 1.5 to 3.5. <14> The component (A) is an oligosaccharide precipitation inhibitor, which contains as active ingredients component (B) a polyhydric alcohol having an IOB value of 4.5 to 5.5 and component (C) a polyhydric alcohol having an IOB value of 1.5 to 3.5. <15> the mass ratio (A) / [(B)+(C)] of the content of the component (A) to the total content of the component (B) and the component (C) is 0.01 to 1; <12> This is the method described above. <16> the mass ratio (A) / [(B)+(C)] of the content of the component (A) to the total content of the component (B) and the component (C) is 0.01 to 1; <13> The composition is as described in <17> the mass ratio (A) / [(B)+(C)] of the content of the component (A) to the total content of the component (B) and the component (C) is 0.01 to 1; <14> The agent is described in <18> The aforementioned <1> ~ <8> 1. A method for suppressing the occurrence of precipitation of component (A) by using component (B) and component (C) when producing the aqueous composition according to any one of the above items. [Example]

[0078] The effects of the present invention will be explained using the following examples and comparative examples. However, the technical scope of the present invention is not limited to the following examples. Unless otherwise specified, each operation is carried out at room temperature (25°C). The content of each component shown in Tables 1 to 7 indicates the content of the pure component. Examples 1 to 16 and Comparative Examples 1 to 2: Aqueous Compositions The aqueous compositions shown in Table 1 were prepared and their deposition-inhibiting effects were evaluated by the following method. The results are also shown in Table 1.

[0079] [Table 1] (Note 1) Trehalose 30H (PFB) (manufactured by Ichimaru Pharcos, 30% purity) (Note 2) KF-6012 (Shin-Etsu Chemical Co., Ltd.) (Note 3) KF-6017 (Shin-Etsu Chemical Co., Ltd.) (Note 4) Amizet 5C (Kawaken Fine Chemicals Co., Ltd.) (Note 5) LIPONIC EG-1 (manufactured by LIPO CHEMICALS INC.) (Note 6) MacbioBride MG-10P (NOF Corporation)

[0080] (Manufacturing method) Components (1) to (10) were mixed uniformly to obtain an aqueous composition.

[0081] (Evaluation method): Precipitation suppression effect The deposition suppression effect was examined by drawing a thin film of the sample on a glass plate using a 6 mil doctor blade, air-drying at 20°C for 15 minutes, and observing each sample under a microscope. The deposition state was observed under an optical microscope at 40x magnification using a polarizing filter. <4-level evaluation criteria> (Judgment): (Evaluation) ◎ (Excellent): No crystal precipitation is observed ○ (Good): Almost no crystal precipitation is observed △ (slightly poor): Crystal precipitation is observed in part of the observation area × (poor): Crystal precipitation is observed over the entire observation area.

[0082] As is clear from the results in Table 1, the aqueous compositions of Examples 1 to 16 of the present invention were superior to the aqueous compositions of Comparative Examples 1 and 2 in the effect of inhibiting precipitation of component (A).

[0083] In contrast, in Comparative Examples 1 and 2, which did not contain component (C) or component (B), the precipitation of component (A) could not be suppressed, and a satisfactory product was not obtained.

[0084] Examples 17 to 32: Wipe-off serum The wipe-off beauty serums shown in Table 2 were prepared and evaluated for non-stickiness and smoothness of the skin after use using the methods described below. The results are also shown in Table 2.

[0085] [Table 2]

[0086] (Manufacturing method) A: Mix ingredients (1) to (10) uniformly. B: A was filled into a bottle to obtain a cosmetic liquid.

[0087] (Evaluation method): No stickiness on skin after application The non-stickiness of the skin after use was evaluated in a use test by a panel of 10 cosmetic evaluation specialists. Each sample was moistened with 2.0 parts by mass of cotton per 1.0 part by mass of cotton, and the samples were applied by wiping the entire face. They were evaluated and scored according to the following evaluation criteria. The average score was calculated from the total scores of all panelists for each sample, and the score was then judged according to the following four-level rating scale. <Absolute evaluation criteria> (Rating): (Evaluation) 5: No stickiness at all 4: Almost no stickiness 3: Neither 2: Feels slightly sticky 1: Very sticky <4-level evaluation criteria> (Judgment): (Average score) A (excellent): 4.0 points or more B (Good): 3.5 points or more, less than 4.0 points C (pass): 3.0 points or more, less than 3.5 points D (poor): Less than 3.0 points

[0088] (Evaluation method): Smooth feeling of skin after application The smooth feeling left on the skin after use was evaluated in a use test by a panel of 10 cosmetic evaluation specialists. Each sample was moistened with 2.0 parts by mass of cotton per 1.0 part by mass of cotton, and the cotton was wiped over the entire face. The samples were evaluated and scored according to the following criteria. The average score was calculated from the total scores of all panelists for each sample, and the score was then judged according to the following four-level rating scale. The smooth feeling on the skin after use was evaluated based on whether the skin felt smooth 5 minutes after use. <Absolute evaluation criteria> (Rating): (Evaluation) 5: Very sensitive 4: Somewhat felt 3: Neither 2: Not much 1: No feeling at all <4-level evaluation criteria> (Judgment): (Average score) A (excellent): 4.0 points or more B (Good): 3.5 points or more, less than 4.0 points C (Acceptable): 3.0 points or more, less than 3.5 points D (poor): Less than 3.0 points

[0089] As is clear from the results in Table 2, the wipe-off beauty serums of Examples 17 to 32 of the present invention were excellent in that they left the skin feeling smooth and non-sticky after application. Furthermore, by using them as wipes, they were not only effective due to the effect of ingredient (A), but also had an excellent effect on clogged pores due to the effect of removing keratin plugs, etc.

[0090] Example 33: Cosmetic serum (oil-in-water type) [Table 3] (Note 7) CARBOPOL 1382 (manufactured by LUBRIZOL ADVANCED MATERIALS) (Note 8) ARISTOFLEX HMB (Clariant Iberica Produccion, SA)

[0091] (Manufacturing method) A: Mix ingredients (1) to (15) uniformly. B: Components (16) to (25) are mixed and dissolved, then added to A at room temperature and emulsified. C: B was filled into a bottle to obtain a cosmetic liquid.

[0092] The beauty serum obtained in this manner was stable, with no crystallization of component (A), and had an excellent effect on preventing clogged pores by suppressing keratin plug formation.

[0093] Example 34: Emulsion (oil-in-water type) [Table 4] (Note 9) KF-6011 (Shin-Etsu Chemical Co., Ltd.) (Note 10) HOSTAPHAT KW340D (Clariant Japan) (Note 11) PLANDOOL-MAS (manufactured by Nippon Fine Chemicals Co., Ltd.) (Note 12) Rice sterol ester (Tsukuno Rice Fine Chemicals Co., Ltd.)

[0094] (Manufacturing method) A: Mix ingredients (1) to (12) uniformly. B: Components (13) to (22) are heated to approximately 70°C, mixed and dissolved uniformly, and then added to A. After emulsification, the mixture is cooled. C: B was filled into a dispenser container to obtain an emulsion.

[0095] The emulsion obtained in this manner was stable, with no crystallization of component (A), and left the skin feeling smooth and non-sticky after application. It also had an excellent effect on clogged pores by suppressing the formation of keratin plugs.

[0096] Example 35: Cream (oil-in-water type) [Table 5]

[0097] (Manufacturing method) A: Heat ingredients (1) to (16) to approximately 70°C and mix uniformly. B: Components (17) to (29) are heated to approximately 70°C, mixed and dissolved uniformly, then added to A, emulsified, and cooled. C: B was filled into a jar to obtain a cream.

[0098] The cream obtained in this manner was stable, with no crystallization of component (A), and had excellent non-sticky and smooth skin after application. It also had excellent anti-pore clogging effects by inhibiting keratin plug formation.

[0099] Example 36: Cream (water-in-oil type) [Table 6] (Note 13) KF-6028P (Shin-Etsu Chemical Co., Ltd.) (Note 14) SY-DP9 (manufactured by Sakamoto Pharmaceutical Co., Ltd.)

[0100] (Manufacturing method) A: Mix ingredients (1) to (5) uniformly. B: Components (6) to (20) are mixed and dissolved, then added to A at room temperature and emulsified. C: B was filled into a dispenser container to obtain a cream.

[0101] The cream obtained in this manner was stable, with no crystallization of component (A), and had excellent non-sticky and smooth skin after application. It also had excellent anti-pore clogging effects by inhibiting keratin plug formation.

[0102] Example 37: Lotion [Table 7] (Note 15) Wilbride S-753D (NOF Corporation)

[0103] (Manufacturing method) A: Components (1) to (5) are uniformly dissolved and mixed at 75°C. B: While maintaining A at 75°C, add a portion of component (19) and emulsify at 70°C. C: After B is cooled to room temperature, it is subjected to high pressure treatment in a microfluidizer. D: Components (6) to (18), the remaining components (19), (20) and (21) are uniformly dissolved and mixed at room temperature. E: Add C to D and mix. F: E was filled into a bottle to obtain a lotion.

[0104] The lotion obtained in this manner was stable, with no crystallization of component (A), and had an excellent effect on preventing clogged pores by suppressing the formation of keratin plugs.

Claims

1. The following components (A) to (C): (A) Oligosaccharides 1% by mass or more (B) Polyhydric alcohol with an IOB value of 4.5 to 5.5 (C) Polyhydric alcohol with an IOB value of 1.5 to 3.5 An aqueous composition comprising:

2. 2. The aqueous composition of claim 1, wherein component (A) is trehalose.

3. 3. The aqueous composition according to claim 1, wherein a mass ratio (A) / [(B)+(C)] of the content of the component (A) to the total content of the component (B) and the component (C) is 0.01 to 1.

4. 3. The aqueous composition according to claim 1, wherein the total content (B)+(C) of the component (B) and the component (C) is 3 to 30% by mass.

5. The aqueous composition according to claim 1 or 2, wherein the content of the component (A) is 3 mass% or more.

6. The aqueous composition according to claim 1 or 2, further comprising a component (D) a nonionic surfactant.

7. The aqueous composition according to claim 6, wherein the component (D) is at least one selected from the group consisting of silicone surfactants and polyoxyalkylene fatty acid alkanolamides.

8. The aqueous composition according to claim 1 or 2, further comprising a component (E) an alkylene oxide derivative represented by general formula (1): Z-{O-(EO)a-(PO)b-(BO)cH}n (1) (In formula (1), n ​​is an integer of 1 to 4, Z is a residue obtained by removing n hydroxy groups from a hydrogen atom or a polyhydric alcohol having 2 to 4 hydroxyl groups, EO is an oxyethylene group, PO is an oxypropylene group, and BO is an oxybutylene group. a, b, and c are the average molar numbers of EO, PO, and BO added, respectively, and are values ​​of 0≦a≦50, 0≦b≦50, and 0≦c≦5. a, b, and c are not all 0, and when a and b are not 0, the mass ratio (PO / EO) is 1 / 5 to 5 / 1. EO and PO may be added randomly or in blocks. When n is 2 or greater, the multiple a's, b's, and c's may be the same or different. When Z is a hydrogen atom, n is 1.)

9. A cosmetic or topical skin preparation comprising the aqueous composition according to claim 1 or 2.

10. The cosmetic or topical skin preparation according to claim 9, which is used by wiping.

11. A method for inhibiting precipitation of component (A) oligosaccharides, which uses component (B) a polyhydric alcohol having an IOB value of 4.5 to 5.5 and component (C) a polyhydric alcohol having an IOB value of 1.5 to 3.

5.

12. A composition for inhibiting the precipitation of component (A) oligosaccharides, comprising as active ingredients component (B) a polyhydric alcohol having an IOB value of 4.5 to 5.5 and component (C) a polyhydric alcohol having an IOB value of 1.5 to 3.5.

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