Transfer tool with blister pack

Abstract

To provide a transfer tool with a blister pack capable of reducing time and labor for adjusting a medicine using the transfer tool.SOLUTION: A transfer tool 1 with a blister pack includes a transfer tool 100 comprising a main body part 110 and a tip mounting part 130, and a blister pack 200 comprising a container body 210 and a lid body 220. A housing chamber 213 provided in the container body 210 comprises a first housing space SP1 for housing the tip mounting part 130 and a second housing space SP2 for housing the main body part 110. A peripheral wall part 212 of the container body 210 of a part defining the second housing space SP2 is provided with an engaging part 217 for sandwiching and holding the main body part 110 in a direction crossing the axial direction of the main body part 110, and the transfer tool 100 is held by the container body 210 only by sandwiching by the engaging part 217.SELECTED DRAWING: Figure 9

Description

[Technical Field]

[0001] The present invention relates to a transfer device with a blister pack, which includes a blister pack and a transfer device enclosed therein. [Background technology]

[0002] In order to prepare a drug to be administered to a patient, etc., a liquid such as distilled water, saline, or glucose solution may be injected into a vial containing a dry drug, etc., and the mixture (dissolution, suspension, etc.) may be carried out inside the vial. After mixing, the liquid drug is transferred from the vial to a syringe, and then administered to the patient using the syringe.

[0003] To facilitate the preparation of such drugs, infusion devices have become popular as auxiliary tools that enable the connection of vials to syringes. The infusion device is attached to both a vial containing a dry drug or the like and a syringe prefilled with a liquid drug (a so-called prefilled syringe), thereby relaying the connection between the syringe and the vial. When in use, the syringe and the vial are connected by the infusion device, and the drug is prepared and transferred (i.e., transferred) in this state.

[0004] This type of transfer device is disclosed in, for example, Japanese Patent Application Laid-Open No. 2004-97253 (Patent Document 1). [Prior art documents] [Patent documents]

[0005] [Patent Document 1] Japanese Patent Application Laid-Open No. 2004-97253 Summary of the Invention [Problem to be solved by the invention]

[0006] From a hygienic standpoint, transfer devices are generally individually packaged in packaging to prevent contamination during storage and transportation. In recent years, blister packs have become popular as packaging materials, as they are easier to open.

[0007] However, simply storing the transfer tool inside the blister pack does not allow the transfer tool to be positioned within the blister pack, so when using it, it is necessary to remove the transfer tool from the blister pack and then attach it to a vial, etc. This creates a problem of making the drug preparation process complicated.

[0008] Therefore, the present invention has been made in consideration of the above-mentioned problems, and aims to provide a transfer device with a blister pack that can reduce the effort required for preparing medicines using the transfer device. [Means for solving the problem]

[0009] The transfer device with a blister pack according to the present invention comprises a transfer device used to connect a vial to a syringe, and a blister pack having an internal storage chamber in which the transfer device is stored before use. The transfer device has a cap-shaped main body having a top plate and a side plate, a puncture needle protruding from the top plate toward the side where the side plate is located, and a tip mounting portion protruding from the top plate toward the side opposite the side plate. The blister pack has a cup-shaped container body having a bottom wall and a peripheral wall, and a lid that closes the open end of the container body. The storage chamber includes a first storage space that houses the tip mounting portion and a second storage space that houses the main body and the puncture needle. The first storage space is defined by the bottom wall and a portion of the peripheral wall closer to the bottom wall, and the second storage space is defined by a portion of the peripheral wall closer to the opening end than the portion defining the first storage space. In the blister pack-equipped transfer device according to the present invention, an engaging portion for clamping and holding the main body in a direction intersecting the axial direction of the main body is provided on the peripheral wall at the portion defining the second storage space, so that the transfer device is held by the container body before use only by being clamped by the engaging portion. [Effects of the Invention]

[0010] According to the present invention, it is possible to provide a transfer device with a blister pack that can reduce the effort required for preparing medicines using the transfer device. [Brief explanation of the drawings]

[0011] [Figure 1] 1 is a perspective view of a transfer tool provided in a transfer tool with a blister pack according to an embodiment, and a vial and a syringe attached thereto. FIG. [Figure 2] FIG. 2 is a perspective view of the transfer device shown in FIG. [Figure 3] 2A and 2B are plan and bottom views of the transfer device shown in FIG. 1. [Figure 4] FIG. 2 is a cross-sectional view of the transfer device shown in FIG. [Figure 5] FIG. 2 is a cross-sectional view showing a state in which a vial is attached to the transfer device shown in FIG. [Figure 6] FIG. 6 is a schematic cross-sectional view showing a state in which a syringe is further attached to the transfer tool in the state shown in FIG. 5. [Figure 7] FIG. 1 is a perspective view of a transfer device with a blister pack according to an embodiment. [Figure 8] FIG. 8 is a plan view of the transfer device with blister pack and the blister pack shown in FIG. 7. [Figure 9] FIG. 8 is a cross-sectional view of the transfer device with a blister pack and the blister pack shown in FIG. 7. [Figure 10] FIG. 8 is a cross-sectional view of the transfer device with a blister pack and the blister pack shown in FIG. 7. [Figure 11] 1 is a cross-sectional view showing a first step of a suitable attachment procedure for attaching a vial to a transfer device with a blister pack according to an embodiment. FIG. [Figure 12] 10 is a cross-sectional view showing a second stage of a suitable attachment procedure for attaching a vial to a transfer device with a blister pack according to an embodiment. FIG. [Figure 13] 10 is a cross-sectional view showing a third step of a preferred attachment procedure for attaching a vial to a transfer device with a blister pack according to an embodiment. FIG. DETAILED DESCRIPTION OF THE INVENTION

[0012] DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, embodiments of the present invention will be described in detail with reference to the drawings. In the following embodiments, the same or common parts are designated by the same reference numerals in the drawings, and the description thereof will not be repeated.

[0013] (Embodiment) FIG. 1 is a perspective view of a transfer device provided in a transfer device with a blister pack according to an embodiment, and a vial and syringe attached thereto. FIGS. 2(A) and 2(B) are perspective views of the transfer device shown in FIG. 1, viewed from different directions. FIGS. 3(A) and 3(B) are a plan view and a bottom view, respectively, of the transfer device shown in FIG. 1. Also, FIGS. 4(A) and 4(B) are cross-sectional views of the transfer device shown in FIG. 1, taken along lines IVA-IVA and IVB-IVB in FIGS. 3(A) and 3(B), respectively. First, with reference to FIGS. 1 to 4, the configurations of a transfer device 100 provided in a transfer device with a blister pack according to this embodiment (see FIG. 7, etc.) and a vial 300 and a syringe 400 attached thereto will be described.

[0014] 1, the infusion device 100 is used in conjunction with a vial 300 and a syringe 400 for the purpose of preparing a drug and then administering the prepared drug to a patient, etc. More specifically, when using the infusion device 100, the vial 300 and the syringe 400 are attached to the infusion device 100.

[0015] Here, vial 300 is pre-filled with first medicament 501 (see FIG. 5, etc.), such as a dry medicament. Meanwhile, syringe 400 is configured as a pre-filled syringe pre-filled with second medicament 502 (see FIG. 6), such as distilled water, physiological saline, glucose solution, etc. Note that first medicament 501 sealed in vial 300 is not limited to a powder or solid such as a dry medicament, but may be a liquid medicament, etc.

[0016] When using the transfer tool 100, the transfer tool 100 is first attached to the vial 300, and then the syringe 400 is attached to the transfer tool 100. This connects the vial 300 and the syringe 400 via the transfer tool 100. Thereafter, a drug preparation operation is performed, including a first transfer operation (introducing the second drug 502 into the vial 300), a mixing operation (mixing the first drug 501 and the second drug 502), and a second transfer operation (introducing the mixed drug into the syringe 400), which will be described later. After this drug preparation operation is completed, the syringe 400 is removed from the transfer tool 100, and the drug is administered to the patient.

[0017] As shown in Fig. 1, vial 300 has a vial body 310, an elastic stopper 320, and a sealing member 330. Vial body 310 has a mouth 311 (see Fig. 5, etc.) at its upper end and a bottom 312 (see Fig. 5, etc.) at its lower end, with an opening 313 (see Fig. 5, etc.) formed in mouth 311. Elastic stopper 320 closes mouth 311 in a resealable manner, and sealing member 330 is provided to cover the edge of elastic stopper 320 and mouth 311 of vial body 310 to prevent elastic stopper 320 from falling off from vial body 310 and to seal any gap between mouth 311 and elastic stopper 320.

[0018] The vial body 310 is made of, for example, a glass or resin member, and the elastic stopper 320 is made of, for example, a rubber or thermoplastic elastomer member. On the other hand, the sealing member 330 is formed by, for example, thermally shrinking a resin film member so that it adheres closely to the elastic stopper 320 and the vial body 310. Here, the sealing member 330 may alternatively be made of a metal film member that is crimped and fixed to the elastic stopper 320 and the vial body 310.

[0019] As described above, first drug 501 is enclosed inside vial 300. First drug 501 is contained inside vial body 310, and is enclosed inside vial 300 by sealing opening 313 of vial body 310 with elastic stopper 320 and sealing member 330 described above. Note that sealing member 330 has cutout portion 331 (see FIG. 5, etc.) at a position corresponding to the center of elastic stopper 320, thereby exposing the center of elastic stopper 320 to the outside.

[0020] 1 to 4, the transfer device 100 comprises a main body 110, a puncture needle 120, and a tip attachment part 130. The transfer device 100 is made of, for example, a resin molded product, and preferably comprises a single member in which the main body 110, the puncture needle 120, and the tip attachment part 130 are integrated. Suitable materials for the transfer device 100 include, for example, acrylonitrile butadiene styrene (ABS) resin, polycarbonate (PC) resin, and polypropylene (PP) resin.

[0021] Main body 110 is a portion that is attached to vial 300 during the drug preparation operation, and has a generally cap-like shape. Main body 110 includes a generally flat top plate 111 and a generally cylindrical side plate 112 that stands downward from the periphery of top plate 111.

[0022] The puncture needle 120 is a part that pierces the elastic stopper 320 of the vial 300 during a drug preparation operation, and is provided on the top plate 111 of the main body 110. More specifically, the puncture needle 120 protrudes from the top plate 111 toward the side where the side plate 112 is located (i.e., downward). The puncture needle 120 has a tubular shape with a sharp tip. When the transfer device 100 is viewed from above, the puncture needle 120 is located in the center of the top plate 111 (i.e., on the axis AX of the main body 110, as shown in Figures 3 and 4).

[0023] Tip mounting part 130 is a portion to which a tip of syringe 400, which will be described later, is attached during a drug preparation operation, and is provided on top plate 111 of main body 110. More specifically, tip mounting part 130 protrudes from top plate 111 toward the side opposite to the side on which side plate 112 is located (i.e., upward). Tip mounting part 130 has a tubular shape, and has a male thread portion 131 provided on its outer circumferential surface. Tip mounting part 130 is located in the center of top plate 111 when transfer device 100 is viewed from above (i.e., on axis AX of main body 110, as shown in Figures 3 and 4).

[0024] The puncture needle 120 and the tip mounting part 130 are provided with a drug passage 140. The drug passage 140 is for connecting the internal space of the vial 300 with the internal space of the syringe 400 during the drug preparation operation. The drug passage 140 passes through the puncture needle 120, the top plate part 111, and the tip mounting part 130 in the vertical direction, connecting one end opening 141 provided on the surface of the puncture needle 120 with the other end opening 142 provided on the tip mounting part 130.

[0025] 2 to 4, the side plate 112 of the main body 110 has a generally rectangular cylindrical shape with four rounded corners, and each of the four corners has a slit 113 extending along the axial direction of the main body 110. As a result, the side plate 112 is essentially divided into four plate-like portions, and is composed of a pair of first plate-like portions facing each other and a pair of second plate-like portions facing each other.

[0026] Each of the pair of first plate-shaped portions, which is one of the two pairs of plate-shaped portions, is provided with a locking portion 114. Locking portion 114 is a claw-shaped portion formed so as to protrude from each of the pair of first plate-shaped portions toward the puncture needle 120. This locking portion 114 is a portion for receiving and holding the opening 311 of vial 300 during the medicine preparation operation.

[0027] 1, syringe 400 has barrel 410, plunger 420, and packing 430 (see FIG. 6). These barrel 410, plunger 420, and packing 430 are pre-assembled, and then filled with second drug 502 (see FIG. 6), so that syringe 400 is configured as a pre-filled syringe filled with second drug 502, as described above. Note that barrel 410 and plunger 420 are configured, for example, from resin members.

[0028] The barrel 410 functions as a container for accommodating the second drug 502, and includes a barrel body 411, a nozzle portion 412 located at the front end of the barrel body 411 in the axial direction, a cylindrical surrounding portion 413 surrounding the nozzle portion 412, a female screw portion 414 (see Figure 6) provided on the inner surface of the surrounding portion 413, and a finger hook portion 415 located at the rear end of the barrel body 411 in the axial direction.

[0029] Of these, nozzle portion 412 functions as an outlet port through which a drug is dispensed when the drug is administered, and a needle hub is connected to the gap between nozzle portion 412 and surrounding portion 413 when the drug is administered. Female thread portion 414 provided on the inner peripheral surface of surrounding portion 413 described above is for fixing the needle hub. Meanwhile, finger hook portion 415 is a portion on which a user can hook their finger when performing various operations on syringe 400, which will be described later, to facilitate handling, and is positioned to protrude outward from barrel body 411.

[0030] Here, the tip portion of the syringe 400, including the nozzle portion 412, the surrounding portion 413, and the female screw portion 414, is generally referred to as the tip, and when the syringe 400 is attached to the infusion device 100, this tip is connected to the tip attachment portion 130 provided on the main body portion 110 of the infusion device 100.

[0031] Plunger 420 is made of a rod-shaped member, and is inserted into barrel 410 from the rear end side of barrel 410, thereby being assembled so as to be slidable relative to barrel 410. A convex portion 421 (see FIG. 6) is provided at the front end of plunger 420, and a male screw portion 422 (see FIG. 6) is provided on the outer circumferential surface of this convex portion 421.

[0032] Packing 430 is used to liquid-tightly seal the drug filled inside barrel 410 at the rear end of barrel 410, and is made of, for example, a rubber or elastomer material. A recessed portion 431 (see FIG. 6) is provided at the rear end of packing 430, and a female screw portion 432 (see FIG. 6) is provided on the inner circumferential surface of this recessed portion 431.

[0033] In the assembled state of syringe 400 (i.e., the state shown in FIGS. 1 and 6 (see FIG. 6 in particular)), convex portion 421 provided at the front end of plunger 420 is inserted into concave portion 431 provided at the rear end of packing 430, and male thread portion 422 provided at convex portion 421 of plunger 420 is threadedly engaged with female thread portion 432 provided at concave portion 431 of packing 430. In this manner, packing 430 is attached to the front end of plunger 420. With this configuration, by increasing or decreasing the insertion depth of plunger 420 into barrel 410, second drug 502 is dispensed from syringe 400 during the first transfer operation, and a mixed drug is introduced into syringe 400 during the second transfer operation.

[0034] Figure 5 is a cross-sectional view showing a state in which a vial is attached to the transfer device shown in Figure 1. Also, Figure 6 is a schematic cross-sectional view showing a state in which a syringe is further attached to the transfer device in the state shown in Figure 5. Next, with reference to Figures 5 and 6 and the aforementioned Figure 1, the operation of attaching vial 300 and syringe 400 to the transfer device 100 described above and the state after attachment will be described.

[0035] 1, when attaching the vial 300 to the transfer tool 100, the transfer tool 100 is first placed over the upper end of the vial 300 in the direction of the arrow shown in the figure. As a result, the upper end of the vial 300 is inserted into the inside of the side plate 112 of the transfer tool 100 from the lower end side of the side plate 112.

[0036] As a result, the mouth 311 provided at the upper end of the vial 300 (more precisely, the sealing member 330 covering the mouth 311) comes into contact with the locking portions 114 provided on the pair of first plate-shaped portions of the transfer device 100. As a result, each of these locking portions 114 is pressed down by the mouth 311 of the vial 300, and elastically deforms radially outward of the transfer device 100.

[0037] Furthermore, by moving the upper end of the vial 300 toward the top plate 111 of the transfer tool 100, the mouth 311 of the vial 300 passes over the above-mentioned locking portions 114. This releases the pressure exerted by the mouth 311 on each of the locking portions 114, and each of these locking portions 114 returns to its original shape, thereby locking onto the lower end (i.e., the constricted portion) of the mouth 311 (see FIG. 5). Therefore, the mouth 311 of the vial 300 is received by the locking portions 114, and the vial 300 is attached to the main body 110 of the transfer tool 100.

[0038] At this time, the upper end surface of vial 300 reaches puncture needle 120 provided on transfer device 100, causing puncture needle 120 to pierce elastic stopper 320 sealing mouth 311 of vial 300. As a result, one end opening 141 of drug passage 140 provided on puncture needle 120 is positioned in the internal space of vial 300, and the internal space of vial 300 and drug passage 140 communicate with each other.

[0039] As a result of the above, the vial 300 can be attached to the transfer device 100 as shown in FIG.

[0040] Next, referring to Figure 1, when connecting the syringe 400 to the transfer tool 100, first, the syringe 400 is attached from above to the transfer tool 100 to which the vial 300 is attached (i.e., the transfer tool 100 in the state shown in Figure 5). Specifically, the syringe 400 is placed above the tip attachment part 130 of the transfer tool 100 to which the vial 300 is attached, and the male thread part 131 provided on the tip attachment part 130 and the female thread part 414 provided on the surrounding part 413 of the syringe 400 are screwed together (see Figure 6). This results in the syringe 400 being attached to the tip attachment part 130 of the transfer tool 100.

[0041] In addition, as a result, the nozzle portion 412 of the syringe 400 is inserted into the other end opening 142 of the drug passage 140 provided in the tip mounting portion 130, and the internal space of the syringe 400 and the drug passage 140 become connected.

[0042] As a result, the syringe 400 can be attached to the transfer tool 100 as shown in Figure 6, and the vial 300 and syringe 400 can be connected via the transfer tool 100. In this connected state, the internal space of the syringe 400 and the internal space of the vial 300 communicate with each other via the drug passage 140 provided in the transfer tool 100.

[0043] After this connection between the vial 300 and the syringe 400 is achieved, the plunger 420 of the syringe 400 is pressed down from the state shown in Figure 6, thereby discharging the second drug 502 filled inside the syringe 400 into the vial 300 via the drug passage 140 provided in the transfer device 100 (first transfer operation).

[0044] This causes the first drug 501 and the second drug 502 to mix together inside the vial 300, and by further shaking the vial 300, the first drug 501 and the second drug 502 are mixed (dissolved, suspended, etc.) (mixing operation).

[0045] Furthermore, the vial 300 and syringe 400 connected by the transfer tool 100 are then rotated together so that they assume an inverted position in which the bottom 312 of the vial 300 is positioned above the mouth 311 of the vial 300.

[0046] Then, the plunger 420 of the syringe 400 is pulled down, and the mixed drug (the drug after the first drug 501 and the second drug 502 are mixed) contained inside the vial 300 is introduced into the syringe 400 via the drug passage 140 provided in the transfer device 100 (second transfer operation).

[0047] After the mixed drug has been introduced into the syringe 400, the syringe 400 is removed from the infusion device 100, and then a needle base is attached to the nozzle portion 412 and surrounding portion 413 of the syringe 400, and the drug is administered (i.e., injected) into the patient.

[0048] Figures 7(A) and 7(B) are perspective views of the blister pack-equipped infusion device according to this embodiment, viewed from different directions. In particular, Figure 7(A) shows the blister pack with the lid partially opened. Figure 8(A) is a plan view of the blister pack-equipped infusion device with the lid opened, and Figure 8(B) is a plan view of only the blister pack container body. Figures 9(A) and 10(A) are cross-sectional views taken along lines IXA-IXA and XA-XA, respectively, in Figure 8(A). Figures 9(B) and 10(B) are cross-sectional views taken along lines IXB-IXB and XB-XB, respectively, in Figure 8(B). In Figures 7(A), 8(A), 9(A), and 10(A), the infusion device 100 is depicted in a darker color for ease of understanding. Next, the configuration of the transfer device with blister packs 1 according to this embodiment will be described with reference to FIGS.

[0049] As shown in Figure 7, the infusion device 1 with a blister pack according to this embodiment includes a blister pack 200 and an infusion device 100 enclosed therein. The infusion device 100 is the infusion device 100 shown in Figures 1 to 6, and more strictly speaking, it is the infusion device 100 shown in Figures 1 to 6 before use (i.e., in an unused state).

[0050] When unused, the transfer device 100 is individually packaged in a blister pack 200 for hygienic reasons. When the transfer device 100 is to be used, the blister pack 200 is opened.

[0051] 7 to 10, blister pack 200 includes container body 210 and lid 220 described above. Container body 210 is cup-shaped and is made of, for example, a resin molded product. Suitable materials for container body 210 include, for example, polyvinyl chloride (PVC) resin, polyethylene terephthalate (PET) resin, polypropylene (PP) resin, etc. Lid 220, on the other hand, is made of a film-like member, such as a nonwoven fabric impregnated with various resin materials.

[0052] The container body 210 has a hollow, generally truncated cone shape with multiple steps, and mainly comprises a bottom wall 211 and a peripheral wall 212. The bottom wall 211 has a flat plate shape, and the peripheral wall 212 stands upright from the periphery of the bottom wall 211 and is configured so that its outer shape widens as it moves away from the bottom wall 211. Here, the peripheral wall 212 has a plurality of steps, which gives the container body 210 a multi-step shape as described above. The container body 210, which is made up of the bottom wall 211 and the peripheral wall 212, has an internal storage chamber 213 in which an unused transfer device 100 is stored.

[0053] The opening end 214 of the container body 210 is located at the upper end of the peripheral wall 212. A flange 215 extends outward from the upper end of the peripheral wall 212 where the opening end 214 is provided. The lid 220 described above is attached to the flange 215 with its outer edge overlapping the flange 215 so as to close the opening end 214 of the container body 210. As a result, when the container is unopened, the storage chamber 213 provided in the container body 210 is airtightly sealed by the lid 220, making it possible to prevent contamination of an unused transfer device 100 stored in the storage chamber 213.

[0054] A grip portion 216 is provided at a portion of the circumference of the flange portion 215. The grip portion 216 is configured by a part of the container body 210 extending in a protruding piece shape further outward from a part of the flange portion 215. The grip portion 216 is a portion that makes it easy to peel the lid body 220 from the container body 210.

[0055] Here, as shown in Figures 7(A), 8(A), 9(A) and 10(A), the transfer device 100 enclosed in the blister pack 200 is contained in the blister pack 200 with its tip attachment portion 130 facing the bottom wall portion 211 of the container body 210, and its main body portion 110 and puncture needle 120 positioned on the opening end 214 side of the container body 210, with its top and bottom facing upside down relative to the top and bottom of the blister pack 200.

[0056] 9 and 10, the storage chamber 213 of the container body 210 includes a first storage space SP1 defined by the bottom wall 211 and the portion of the peripheral wall 212 closer to the bottom wall 211, and a second storage space SP2 defined by the portion of the peripheral wall 212 closer to the opening end 214 than the portion defining the first storage space SP1. The tip attachment portion 130 of the transfer device 100 is housed in the first storage space SP1, and the main body 110 and the puncture needle 120 of the transfer device 100 are housed in the second storage space SP2.

[0057] The reason why the transfer tool 100 is sealed in the blister pack 200 with the top and bottom of the blister pack 200 and the top and bottom of the transfer tool 100 facing inversely is related to the procedure for attaching the vial 300 to the transfer tool 100, which will be explained later, and the details of this procedure will be explained later.

[0058] 8 to 10, in the blister pack-equipped transfer device 1 according to this embodiment, an engagement portion 217 is provided on the peripheral wall 212 of the container body 210 of the blister pack 200 at a portion that defines the second storage space SP2. The engagement portion 217 is a portion for clamping and holding the main body 110 of the transfer device 100 in a direction intersecting the axial direction of the main body 110 (i.e., the extension direction of the axis AX of the main body 110 shown in the figures).

[0059] More specifically, the engaging portion 217 is constituted by a pair of protrusions provided at predetermined positions on the peripheral wall 212 of the container body 210, and each of the pair of protrusions is positioned so as to protrude further inwardly of the container body 210 than the portion of the peripheral wall 212 adjacent to the protrusion. The pair of protrusions are provided on opposing portions of the peripheral wall 212 that sandwich the axis AX of the main body 110 of the transfer device 100 so as to sandwich the main body 110 in one direction intersecting the axial direction of the main body 110.

[0060] As shown in Figure 8, the distance D1 between the pair of protrusions that make up the engaging portion 217 (i.e., the fitting margin of the main body 110 of the transfer device 100) is configured to be slightly smaller than the width W1 of the main body 110 of the transfer device 100 at the portion that is sandwiched by the engaging portions 217. As a result, when the transfer device 100 is housed in the container body 210, the main body 110 of the transfer device 100 elastically deforms so as to push the engaging portions 217 apart, and the restoring force brings the engaging portions 217 into pressure contact with the main body 110 of the transfer device 100, thereby enabling the container body 210 to hold the transfer device 100. Therefore, the position of the transfer device 100 within the blister pack 200 is determined by the holding of the transfer device 100 by the container body 210.

[0061] In the blister pack-equipped transfer device 1 according to this embodiment, the transfer device 100 is held by the container body 210 before use simply by clamping the main body 110 of the transfer device 100 with the above-mentioned engaging portion 217. This clamping by the engaging portion 217 only restricts the movement of the transfer device 100 in a direction intersecting the axial direction of the main body 110 of the transfer device 100, so movement of the transfer device 100 in the axial direction of the main body 110 of the transfer device 100 is not basically restricted, and when an external force in the axial direction is applied to the transfer device 100 against the holding force created by the clamping by the above-mentioned engaging portion 217, the transfer device 100 comes off the container body 210 relatively easily. However, as long as this axial external force is not applied to the transfer tool 100, the transfer tool 100 can be prevented from moving inside the blister pack 200, and therefore the transfer tool 100 will not be released from its hold by the container body 210 during storage, transportation, etc.

[0062] Therefore, by adjusting the above-mentioned distance D1 and width dimension W1 while taking into consideration the material of the transfer tool 100, the material of the container body 210 of the blister pack 200, the thickness of the side plate portion 112 of the transfer tool 100, the thickness of the peripheral wall portion 212 of the container body 210, the contact area between the side plate portion 112 and the engagement portion 217, etc., it is possible to appropriately determine the position of the transfer tool 100 inside the blister pack 200 while optimizing the holding force of the container body 210 on the transfer tool 100, and it becomes possible to attach the vial 300 to the transfer tool 100 in accordance with the attachment procedure described later.

[0063] 9, the engaging portion 217 is provided only at a position on the peripheral wall 212 defining the second storage space SP2 closest to the bottom wall 211, so that it is positioned opposite only the end of the side plate 112 constituting the main body 110 of the transfer device 100 that is on the tip mounting portion 130 side in the axial direction of the main body 110. This configuration reduces the contact area between the engaging portion 217 and the main body 110 of the transfer device 100, preventing the holding force of the container body 210 against the transfer device 100 from increasing more than necessary.

[0064] 8 to 10, in the blister pack-equipped transfer device 1 according to this embodiment, a guide portion 218 is provided on the peripheral wall portion 212 of the container body 210 of the blister pack 200, in a portion that defines the second storage space SP2 and does not have the above-mentioned engagement portion 217. Unlike the engagement portion 217, the guide portion 218 is a portion that restricts the main body 110 of the transfer device 100 from tilting.

[0065] More specifically, like the engaging portion 217 described above, the guide portion 218 is configured by a pair of protrusions provided at predetermined positions on the peripheral wall portion 212 of the container body 210, and each of the pair of protrusions is positioned so as to protrude more inwardly of the container body 210 than the portion of the peripheral wall 212 adjacent to the protrusion. The pair of protrusions are provided on opposing portions of the peripheral wall portion 212 that sandwich the axis AX of the main body portion 110 so that the main body portion 110 is positioned between them in one direction intersecting the axial direction of the main body portion 110 of the transfer device 100.

[0066] 8, the distance D2 between the pair of protrusions that make up the guide section 218 is configured to be slightly larger than the width W2 of the portion of the main body 110 of the transfer device 100 that is located between the guide sections 218. As a result, when the transfer device 100 is housed in the container body 210, the gap between the portion where the guide section 218, which is configured by the pair of protrusions, is provided and the main body 110 of the transfer device 100 is reduced compared to the surrounding area, thereby restricting the tilting of the main body 110 of the transfer device 100 and, ultimately, effectively preventing the transfer device 100 from tilting inside the container body 210.

[0067] Although the positions at which the above-mentioned engaging portion 217 and guide portion 218 are provided in the circumferential direction of peripheral wall portion 212 of container body 210 are not particularly limited, in this embodiment, a pair of protrusions constituting engaging portion 217 and a pair of protrusions constituting guide portion 218 are alternately provided at 90° intervals. This configuration not only makes it possible to properly maintain the orientation of transfer device 100 inside container body 210 with a small number of protrusions, but also prevents the holding force of container body 210 with respect to transfer device 100 from becoming stronger than necessary.

[0068] 7 to 10 (see particularly FIG. 7(B)), in the blister pack-equipped transfer device 1 according to this embodiment, a plurality of hollow columnar sections 219 are provided on the peripheral wall section 212 of the container body 210 of the blister pack 200 at a portion where a plurality of stepped sections are provided, the peripheral wall section 212 protruding downward in the axial direction of the container body 210. More specifically, four of these hollow columnar sections 219 are provided in a dotted row along the circumferential direction of the peripheral wall section 212.

[0069] By providing multiple hollow columnar sections 219 in the circumferential direction of the peripheral wall section 212 of the container body 210, which has a hollow, approximately frustum-shaped shape in this manner, the rigidity of the container body 210 as a whole is increased, not only can unintended deformation of the container body 210 be suppressed, but also a large gap is formed between the container body 210 and the transfer device 100 contained therein, so that even if an external force is applied to the container body 210 due to, for example, being dropped, the impact on the transfer device 100 can be effectively reduced.

[0070] 11 to 13 are cross-sectional views showing first to third steps of a suitable procedure for attaching a vial to the infusion device with a blister pack according to this embodiment. The following describes in detail the suitable procedure for attaching a vial 300 to the infusion device 100 in the infusion device with a blister pack 1 according to this embodiment.

[0071] As described above, in the blister pack-equipped infusion device 1 according to this embodiment, the infusion device 100 enclosed in the blister pack 200 is held only by the engagement portion 217 provided on the container body 210 of the blister pack 200, which clamps the main body 110 of the infusion device 100. Therefore, when an external force is applied to the infusion device 100 along the axial direction of the main body 110, the infusion device 100 is relatively easily detached from the container body 210. Therefore, in the blister pack-equipped infusion device 1 according to this embodiment, it is possible to attach a vial 300 to the infusion device 100 while the infusion device 100 remains housed in the container body 210 of the blister pack 200, without removing the infusion device 100 from the blister pack 200.

[0072] That is, in the blister pack-equipped infusion device 1 according to this embodiment, first, the lid 220 of the blister pack 200 is peeled off from the container body 210, exposing the open end 214 of the container body 210, and thereby exposing the infusion device 100 housed in the container body 210 to the outside. In this state, the infusion device 100 is held by the container body 210, and the main body 110 and the puncture needle 120 of the infusion device 100 face the outside via the open end 214 of the container body 210.

[0073] 11, the container body 210 is turned upside down while the transfer tool 100 is held by the container body 210, and the transfer tool 100 held by the container body 210 is placed above the vial 300. In this state, the transfer tool 100, together with the container body 210, is placed over the upper end of the vial 300.

[0074] 12, the upper end of the vial 300 is inserted into the side plate 112 of the transfer device 100, which is held by the container body 210, from the lower end side of the side plate 112. At this time, the mouth 311 of the vial 300 is received by the locking portion 114 provided on the transfer device 100, thereby attaching the vial 300 to the main body 110 of the transfer device 100, and the puncture needle 120 provided on the transfer device 100 pierces the elastic stopper 320 that seals the mouth 311 of the vial 300.

[0075] 13, the container body 210 is removed from the transfer tool 100 to which the vial 300 is attached. Specifically, the container body 210 is removed from the transfer tool 100 by moving the container body 210 in a direction away from the vial 300.

[0076] At this time, the transfer tool 100 is held by the engaging portion 217 of the container body 210, but the holding force of this engaging portion 217 is weaker than the locking force of the locking portion 114 of the transfer tool 100 on the mouth portion 311 of the vial 300 when the vial 300 is attached to the transfer tool 100 as described above, and the container body 210 is smoothly detached from the transfer tool 100.

[0077] As a result of the above, the vial 300 can be attached to the transfer device 100 as shown in FIG.

[0078] In this way, the transfer device with blister pack 1 according to this embodiment eliminates the conventionally required step of first removing the transfer device from the blister pack and then attaching the removed transfer device to a vial, thereby significantly reducing the time and effort required for preparing a drug using the transfer device. This makes it easier to prepare a drug, resulting in a user-friendly transfer device.

[0079] The characteristic configuration of the transfer device with blister pack 1 according to the present embodiment described above can be summarized as follows.

[0080] [Appendix 1] a transfer tool used to connect a vial to a syringe; a blister pack having a storage chamber therein and storing the transfer device before use in the storage chamber, The transfer tool has a cap-shaped main body having a top plate and a side plate, a puncture needle protruding from the top plate toward the side where the side plate is located, and a tip mounting portion protruding from the top plate toward the side opposite to the side where the side plate is located, The blister pack has a cup-shaped container body having a bottom wall portion and a peripheral wall portion, and a lid body that closes an open end of the container body, the accommodation chamber includes a first accommodation space that accommodates the tip mounting portion and a second accommodation space that accommodates the main body portion and the puncture needle; the first storage space is defined by the bottom wall portion and a portion of the peripheral wall portion closer to the bottom wall portion, the second housing space is defined by a portion of the peripheral wall portion that is closer to the opening end than a portion that defines the first housing space, A transfer device with a blister pack, in which an engaging portion for clamping and holding the main body portion in a direction intersecting the axial direction of the main body portion is provided on the peripheral wall portion of the part defining the second storage space, so that the transfer device is held by the container body before use only by being clamped by the engaging portion.

[0081] [Appendix 2] A transfer device with a blister pack as described in Appendix 1, in which the engagement portion is provided only on the peripheral wall portion of the side plate portion that faces the end portion of the main body portion on the tip mounting portion side in the axial direction.

[0082] [Appendix 3] the engaging portion includes a pair of protrusions that sandwich the main body portion in one direction intersecting an axial direction of the main body portion, A transfer device with a blister pack described in Appendix 1 or 2, wherein the pair of protrusions are provided on opposing parts of the peripheral wall portion that sandwich the axis of the main body portion therebetween.

[0083] [Appendix 4] A transfer device with a blister pack described in any of Appendices 1 to 3, wherein a guide portion is provided on the peripheral wall portion of the portion that defines the second storage space and does not have the engagement portion, to limit the tilting of the main body portion by reducing the gap between the peripheral wall portion and the main body portion.

[0084] [Appendix 5] the container body has a hollow, generally frustum-shaped shape with a plurality of step portions provided on the peripheral wall portion, A transfer device with a blister pack described in any of Appendices 1 to 4, in which a plurality of hollow columnar portions protruding from the peripheral wall portion in the axial direction of the container body at the portion where the plurality of step portions are provided are arranged in a dotted row along the circumferential direction of the peripheral wall portion.

[0085] (Other forms, etc.) In the above-mentioned embodiment of the transfer device with a blister pack, an example has been given in which, in addition to an engagement portion for holding the transfer device, a guide portion for limiting the tilting of the transfer device is provided on the container body of the blister pack, but the guide portion does not necessarily have to be provided on the container body.

[0086] Furthermore, in the above-described embodiment of the transfer device with blister pack, an example has been given in which a pair of protrusions constituting the engagement portion are provided on opposing portions of the peripheral wall of the container body, sandwiching the axis of the main body, but this configuration is not necessarily required, and three or more protrusions constituting the engagement portion may be arranged, for example, evenly or unevenly along the circumferential direction of the peripheral wall of the container body.

[0087] Furthermore, in the above-described embodiment of the transfer device with blister pack, an example has been given in which a pair of protrusions constituting the guide portion are provided on opposing portions of the peripheral wall of the container body, sandwiching the axis of the main body portion therebetween, but this configuration is not necessarily required, and when the guide portion is provided on the peripheral wall of the container body, three or more protrusions constituting the guide portion may be arranged, for example, evenly or unevenly along the circumferential direction of the peripheral wall of the container body.

[0088] Here, a particularly suitable example of a configuration other than those disclosed in the above-described embodiments is one in which the container body of the blister pack does not have a guide portion, but instead has three or four protrusions that constitute the engagement portion. In this case, the three or four protrusions that constitute the engagement portion are preferably evenly spaced along the circumferential direction of the peripheral wall of the container body. That is, if three protrusions that constitute the engagement portion are provided, they may be spaced every 120° along the circumferential direction of the container body, and if four protrusions that constitute the engagement portion are provided, they may be spaced every 90° along the circumferential direction of the container body. This configuration makes it possible to more accurately position the transfer tool inside the blister pack while avoiding an unnecessarily complex shape of the blister pack (particularly the shape of the container body), and also makes it possible to optimize the holding force of the container body against the transfer tool without increasing it more than necessary.

[0089] Furthermore, in the above-mentioned embodiment of the transfer device with blister pack, the engaging portion and guide portion are configured as protrusions, but these do not necessarily have to be configured as protrusions, and the shape, size, number, formation position, etc. can be changed as appropriate.

[0090] As such, the above-described embodiments disclosed herein are illustrative in all respects and are not restrictive. The technical scope of the present invention is defined by the claims, and includes all modifications within the meaning and scope of the claims. [Explanation of symbols]

[0091] 1 Transfer tool with blister pack, 100 Transfer tool, 110 Main body, 111 Top plate, 112 Side plate, 113 Slit, 114 Locking portion, 120 Puncture needle, 130 Tip mounting portion, 131 Male thread portion, 140 Drug passage, 141 One end opening, 142 Other end opening, 200 Blister pack, 210 Container body, 211 Bottom wall, 212 Peripheral wall, 213 Storage chamber, 214 Opening end, 215 Flange, 216 Handle portion, 217 Engagement portion, 218 Guide portion, 219 Hollow columnar portion, 220 Lid, 300 Vial, 310 Vial body, 311 Mouth portion, 312 Bottom, 313 Opening, 320 Elastic stopper, 330 Sealing member, 331 missing portion, 400 syringe, 410 barrel, 411 barrel body, 412 nozzle portion, 413 surrounding portion, 414 female thread portion, 415 finger hook portion, 420 plunger, 421 convex portion, 422 male thread portion, 430 packing, 431 concave portion, 432 female thread portion, 501 first drug, 502 second drug, SP1 first storage space, SP2 second storage space, AX axis.

Claims

1. a transfer tool used to connect a vial to a syringe; a blister pack having a storage chamber therein and storing the transfer device in the storage chamber before use, The transfer tool has a cap-shaped main body having a top plate and a side plate, a puncture needle protruding from the top plate toward the side where the side plate is located, and a tip attachment portion protruding from the top plate toward the side opposite to the side where the side plate is located, The blister pack has a cup-shaped container body having a bottom wall portion and a peripheral wall portion, and a lid body that closes an open end of the container body, the accommodation chamber includes a first accommodation space that accommodates the tip mounting portion and a second accommodation space that accommodates the main body portion and the puncture needle, the first storage space is defined by the bottom wall portion and a portion of the peripheral wall portion close to the bottom wall portion, the second accommodating space is defined by a portion of the peripheral wall portion that is closer to the opening end than a portion that defines the first accommodating space, A transfer device with a blister pack, in which an engaging portion for clamping and holding the main body portion in a direction intersecting the axial direction of the main body portion is provided on the peripheral wall portion of the part defining the second storage space, so that the transfer device is held by the container body before use only by being clamped by the engaging portion.

2. 2. A transfer device with a blister pack as described in claim 1, wherein the engaging portion is provided only on the peripheral wall portion of the side plate portion facing the end portion of the main body portion on the tip mounting portion side in the axial direction.

3. the engaging portion includes a pair of protrusions that sandwich the main body portion in one direction intersecting the axial direction of the main body portion, The transfer device with a blister pack according to claim 1, wherein the pair of protrusions are provided on opposing portions of the peripheral wall portion sandwiching the axis of the main body portion therebetween.

4. A transfer device with a blister pack as described in claim 1, wherein a guide portion is provided on the peripheral wall portion of the portion that defines the second storage space and does not have the engagement portion, to limit tilting of the main body portion by reducing the gap between the peripheral wall portion and the main body portion.

5. the container body has a hollow, generally frustum-shaped shape with a plurality of step portions provided on the peripheral wall portion, A transfer device with a blister pack as described in claim 1, wherein a plurality of hollow columnar portions protruding from the peripheral wall portion in the axial direction of the container body at the portion where the plurality of step portions are provided are arranged in a dotted row along the circumferential direction of the peripheral wall portion.

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