Compositions containing encapsulated and non-encapsulated bixlosone

Abstract

Described herein are compositions comprising encapsulated and unencapsulated vixlozone. Also described herein are methods for preparing the compositions. Also described herein are methods for controlling undesirable vegetation using the compositions.

Description

[Technical Field]

[0001] Described herein are compositions comprising encapsulated and unencapsulated vixlozone. Also described herein are methods for preparing the compositions. Also described herein are methods for controlling undesirable vegetation using the compositions. [Background technology]

[0002] The formulation of biclozone often requires a balance between crop safety and efficacy. Generally, encapsulated biclozone is more selective and therefore safer than non-encapsulated biclozone, but less effective. In addition, for example, target crop damage and non-target crop damage due to spray drift must be considered. These balancing considerations limit the formulations containing biclozone. Summary of the Invention [Means for solving the problem]

[0003] It has been discovered herein that compositions containing both encapsulated and non-encapsulated vixlozone are safe and effective. Formulations containing a mixture of encapsulated and non-encapsulated vixlozone provide a surprising enhancement in safety, such that non-target crop damage in the absence of a safener is equivalent to non-target crop damage in the presence of a safener. In other words, ZC vixlozone formulations (containing a mixture of vixlozone CS and vixlozone SC) provide crop safety that is at least equal to, and in many cases greater than, the level of phytotoxicity provided by conventional safeners in combination with non-encapsulated vixlozone (vixlozone SC). In addition, ZC vixlozone formulations also provide volatility control after soil application, thereby providing an additional safety benefit to non-target plants when they are exposed to spray drift events.

[0004] Safeners are not strictly required for compositions containing both encapsulated and unencapsulated bixlosone. Compositions containing both encapsulated and unencapsulated bixlosone in ZC formulations are effective and can be used in a variety of forms.

[0005] Enhanced target crop safety can also be achieved by adding safeners to the Bixlozone ZC formulation. In these modified Bixlozone ZC formulations, the Bixlozone ZC formulation itself provides the majority of the safening effect.

[0006] In one embodiment, the present disclosure is directed to a composition comprising (i) encapsulated bixalozone, (ii) unencapsulated bixalozone, and (iii) optionally, an additional active ingredient, wherein the composition does not include a safener.

[0007] In another embodiment, the present disclosure is directed to a method of preparing a composition comprising: I) encapsulating bixlozone; and II) forming a mixture comprising (i) encapsulated bixlozone, (ii) unencapsulated bixlozone, and iii) optionally, an additional active ingredient, wherein the composition does not contain a safener.

[0008] In yet another embodiment, the present disclosure is directed to a method for controlling undesirable vegetation, comprising applying to the undesirable vegetation or locus thereof, or to the soil or crop, a composition comprising (i) encapsulated bixlozone, (ii) unencapsulated bixlozone, and (iii) optionally, additional active ingredients, wherein the composition does not contain a safener, to prevent the emergence or growth of the undesirable vegetation. [Brief explanation of the drawings]

[0009] [Figure 1]

[0023] Figure 1 shows an exemplary embodiment of early post-emergence application of herbicidal compositions according to the present disclosure. Twelve tests were performed for each composition. [Figure 2]

[0023] Figure 1 shows an exemplary embodiment of early post-emergence application of herbicidal compositions according to the present disclosure. Twelve trials were performed for each composition, evaluating each growth stage. [Figure 3]

[0023] Figure 1 shows an exemplary embodiment of early post-emergence application of herbicidal compositions according to the present disclosure. Twelve trials were performed for each composition, evaluating each growth stage. [Figure 4] 1 shows an exemplary embodiment of early post-emergence application of a herbicide composition according to the present disclosure, followed by harvest without adversely affecting quantity and quality. Four trials were performed for each composition, using grouped evaluation timings. [Figure 5] 1 shows an exemplary embodiment of post-sowing pre-emergence application of a herbicide composition according to the present disclosure. [Figure 6] 1 shows an exemplary embodiment of post-sowing pre-emergence application of a herbicide composition according to the present disclosure. DETAILED DESCRIPTION OF THE INVENTION

[0010] This specification uses examples to illustrate the disclosure, including the best mode, and to enable those skilled in the art to practice the disclosure, including making and using any compositions or systems and performing any incorporated methods. The patentable scope of the disclosure is defined by the claims, and may include other examples that occur to those skilled in the art. Such other examples are intended to be within the scope of the claims if they have elements that do not differ from the literal language of the claims, or if they contain equivalent elements that differ insubstantial from the literal language of the claims.

[0011] As used herein, the terms "comprise," "including," "include," "including," "having," "having," "containing," "characterized by," or other variations thereof, are intended to include a non-exclusive inclusion, subject to any limitations expressly stated. For example, a composition, mixture, process, or method that includes a list of elements is not necessarily limited to only those elements and may include other elements not expressly listed or inherent to such composition, mixture, process, or method.

[0012] The transitional phrase "consisting of" excludes any element, step, or ingredient not specified. In the case of a claim, such would close the claim to the inclusion of materials other than those recited, apart from impurities normally associated therewith. When the phrase "consisting of" appears in a clause in the body of a claim rather than immediately following the preamble, it limits only the elements set forth in that clause; other elements are not excluded from the claim as a whole.

[0013] The transitional phrase "consisting essentially of" is used to define a composition or method that includes materials, steps, features, components, or elements in addition to those literally disclosed, provided that these additional materials, steps, features, components, or elements do not materially affect the basic and novel characteristics of the claimed invention. The term "consisting essentially of" occupies a middle ground between "comprising" and "consisting of." The use of "consisting essentially of" herein enables applicant, as compiler, to define the claimed invention by excluding any material, step, feature, or method that applicant considers not essential to the claimed invention, but that may be known in the prior art and that may otherwise be included in the claimed invention, regardless of whether such inclusion or exclusion is specifically set forth herein. Applicant's exclusion of any material, step, feature, or method may be solely for the purpose of eliminating prior art elements that affect the novelty, and therefore patentability, of the claimed invention. Thus, the use of "consisting essentially of" herein does not require explicit support from the specification to exclude prior art elements from the claimed invention if the inclusion of said prior art elements would be detrimental to the patentability of the claimed invention.

[0014] It should be readily understood that where the invention or portions thereof are defined in open-ended terms such as "comprising," the statement should also be construed to describe such invention using the terms "consisting essentially of" or "consisting of" (unless otherwise specified).

[0015] Furthermore, unless expressly stated otherwise, "or" refers to an inclusive "or" and not an exclusive "or." For example, a condition A or B is satisfied by any one of the following: A is true (or exists) and B is false (or does not exist), A is false (or does not exist) and B is true (or exists), and both A and B are true (or exist).

[0016] Furthermore, the indefinite articles "a" and "an" preceding an element or component of the present invention are intended to be open-ended regarding the number of instances (i.e., occurrences) of that element or component. Thus, "a" or "an" should be read to include one or at least one, and singular forms of elements or components also include plurals unless the number clearly implies a singular number. The term "optionally" in connection with an ingredient or method in the present formulation means "present or absent" in the alternative. An "optional" ingredient is "present" or "absent" independently of the presence or absence of other formulation ingredients or steps, unless otherwise stated or listed.

[0017] As used herein, depending on the context in which it is used, the term "about" provides an estimate of a value relevant to the claimed invention, where the estimate is reasonable as such information would be understood or interpreted by one of ordinary skill in the art in light of what is known in connection with the description of the invention and from publicly available information. Generally, the term "about" as used herein means that the estimate falls within ±10% of the relevant value. Bixlozone is a herbicide recently introduced by FMC, with the CAS name 2-(2,4-dichlorophenyl)methyl-4,4-dimethyl-3-isoxazolidinone. For convenience, Bixlozone is commercially available as "Overwatch" (formulated material) and is also referred to as "DCPMI," "F9600," "2,4-DC," and "dichloroclomazone." In one embodiment, Bixlozone can be technical-grade Bixlozone, with a purity range of 90-95% by weight. In another embodiment, Bixlozone can be a composition comprising 2-(2,4-dichlorophenyl)methyl-4,4-dimethyl-3-isoxazolinone that is greater than 95% pure by weight. In another embodiment, "pure Bixlozone" refers to 2-(2,4-dichlorophenyl)methyl-4,4-dimethyl-3-isoxazolinone that is 100% pure.

[0018] As used herein, "wt %" refers to the weight percent of the recited component relative to the total weight of the recited composition.

[0019] The embodiments of the present disclosure may be combined in any manner.

[0020] Embodiments of the compositions of the present disclosure include the following:

[0021] Embodiment A1. The composition described in the Summary of the Invention wherein unencapsulated bixlosone is provided by the SC component of the formulation.

[0022] Embodiment A2. The composition of embodiment A1, wherein the encapsulated bixlozone is provided by the CS component of the formulation.

[0023] Embodiment A3. The composition of embodiment A1, wherein the bixlozone in the SC component of the formulation is available for diffusion upon dilution.

[0024] Embodiment A4. The composition of embodiment A2, wherein the bixlozone in the CS component of the formulation is not available for diffusion upon dilution.

[0025] Embodiment A5. A composition described in embodiment A4, wherein the bixlozone in the CS component of the formulation is available to the locus of vegetation after application.

[0026] Embodiment B1. The composition described in the Summary of the Invention wherein the encapsulated bixlosone and unencapsulated bixlosone are present in a ratio ranging from about 1:9 to about 9:1.

[0027] Embodiment B2. The composition of Embodiment B1 wherein the encapsulated bixlosone and unencapsulated bixlosone are present in a ratio ranging from about 1:8 to about 8:1.

[0028] Embodiment B3. The composition of Embodiment B2 wherein the encapsulated bixlosone and unencapsulated bixlosone are present in a ratio ranging from about 1:7 to about 7:1.

[0029] Embodiment B4. The composition of Embodiment B3 wherein the encapsulated bixlosone and unencapsulated bixlosone are present in a ratio ranging from about 1:6 to about 6:1.

[0030] Embodiment B5. The composition of Embodiment B4, wherein the encapsulated bixlosone and unencapsulated bixlosone are present in a ratio ranging from about 1:5 to about 5:1.

[0031] Embodiment B6. The composition of Embodiment B5, wherein the encapsulated bixlosone and unencapsulated bixlosone are present in a ratio ranging from about 1:4 to about 4:1.

[0032] Embodiment B7. The composition of Embodiment B6, wherein the encapsulated bixlosone and unencapsulated bixlosone are present in a ratio ranging from about 1:3 to about 3:1.

[0033] Embodiment B8. The composition of Embodiment B7, wherein the encapsulated bixlosone and unencapsulated bixlosone are present in a ratio ranging from about 1:2 to about 2:1.

[0034] Embodiment B9. The composition of Embodiment B6, wherein the encapsulated bixlosone and unencapsulated bixlosone are present in a ratio ranging from about 1:1 to about 1:1.

[0035] Embodiment C1. The composition described in the Summary of the Invention, wherein the encapsulated bixlozone is encapsulated with a material selected from synthetic polymers, polyurea, polyurethane, polyacrylate, polyamide, polyvinyl alcohol, polyvinylpyrrolidone, semi-synthetic materials, modified cellulose, modified starch derivatives, natural materials, gum arabic, agar, dextrin, alginic acid, alginates, biodegradable natural polymers, collagen, polysaccharides, starch, dextrin, wax, chitosan, alginate, cellulose, gelatin, derivatives thereof, and combinations thereof.

[0036] Embodiment C2. The composition of embodiment C1, wherein the encapsulated bixlozone is encapsulated with a material selected from polyurea, biodegradable natural polymers, chitosan, wax, alginate, cellulose, gelatin, and combinations thereof.

[0037] Embodiment C3. The composition of embodiment C1, wherein the encapsulated bixlozone is encapsulated in a synthetic polymer.

[0038] Embodiment C4. The composition of embodiment C3, wherein the encapsulated bixlozone is encapsulated with polyurea.

[0039] Embodiment D1. The composition described in the Summary of the Invention, wherein the additional active ingredient is encapsulated with a material selected from synthetic polymers, polyurea, polyurethane, polyacrylate, polyamide, polyvinyl alcohol, polyvinylpyrrolidone, semi-synthetic materials, modified cellulose, modified starch derivatives, natural materials, gum arabic, agar, dextrin, alginic acid, alginates, biodegradable natural polymers, collagen, polysaccharides, starch, dextrin, wax, chitosan, alginate, cellulose, gelatin, derivatives thereof, and combinations thereof.

[0040] Embodiment D2. The composition of embodiment D1, wherein the additional active ingredient is encapsulated with a material selected from polyurea, biodegradable natural polymers, chitosan, wax, alginate, cellulose, gelatin, and combinations thereof.

[0041] Embodiment D3. The composition of embodiment D1, wherein the additional active ingredient is encapsulated in a synthetic polymer.

[0042] Embodiment D4. The composition of embodiment D3, wherein the additional active ingredient is encapsulated in polyurea.

[0043] Embodiment E1. The composition described in the Summary of the Invention wherein the additional active ingredient is selected from beflubutamid, beflubutamid-M, petoxamide, clomazone, and combinations thereof.

[0044] Embodiment E2. The composition of embodiment E1, wherein the additional active ingredient is selected from beflubutamide.

[0045] Embodiment E3. The composition of embodiment E1, wherein the additional active ingredient is selected from beflubutamide-M.

[0046] Embodiment E4. The composition of embodiment E1, wherein the additional active ingredient is selected from petoxamide.

[0047] Embodiment E5. The composition of embodiment E1, wherein the additional active ingredient is selected from clomazone.

[0048] Embodiment F1. The composition described in the Summary of the Invention wherein the encapsulated bixlozone is encapsulated separately from the additional active ingredient(s).

[0049] Embodiment F2. The composition described in the Summary of the Invention wherein the bixlozone and additional active ingredient are co-encapsulated.

[0050] Embodiment G1. The composition described in the Summary of the Invention further comprising an adjuvant selected from dispersants, surfactants, biocides, antifoaming agents, antifreeze agents, rheology modifiers, wetting agents, solvents, salts, and combinations thereof.

[0051] Embodiment G2. The composition of embodiment G1 further comprising an adjuvant selected from dispersants, surfactants, biocides, antifoaming agents, antifreeze agents, rheology modifiers, wetting agents, solvents, and combinations thereof.

[0052] Embodiment G3. The composition of embodiment G1 further comprising a dispersant.

[0053] Embodiment G4. The composition of embodiment G1 further comprising a surfactant.

[0054] Embodiment G5. The composition of embodiment G1 further comprising a biocide.

[0055] Embodiment G6. The composition of embodiment G1 further comprising an antifoaming agent.

[0056] Embodiment G7. The composition of embodiment G1 further comprising an antifreeze agent.

[0057] Embodiment G8. The composition of embodiment G1 further comprising a rheology modifier.

[0058] Embodiment G9. The composition of embodiment G1 further comprising a humectant.

[0059] Embodiment G10. The composition of embodiment G1 further comprising a solvent.

[0060] Embodiment G11. The composition of embodiment G1 further comprising a salt.

[0061] Embodiment G12. The composition of embodiment G10 further comprising a salt selected from sodium nitrate, calcium chloride, and combinations thereof.

[0062] Embodiment G13. The composition of embodiment G1 further comprising two or more adjuvants.

[0063] Embodiment G14. The composition of embodiment G1 further comprising three or more adjuvants.

[0064] Embodiment G15. The composition of embodiment G1 further comprising four or more adjuvants.

[0065] Embodiment H1. The composition described in the Summary of the Invention in a form selected from a premix and a tank mix.

[0066] Embodiment H2. The composition of Embodiment H1 which is a premix.

[0067] Embodiment H3. The composition of embodiment H1 which is a tank mix.

[0068] The composition embodiments of the present disclosure can be combined with the methods of the preparation embodiments of the present disclosure in any manner.Similarly, the methods of the preparation embodiments of the present disclosure can be combined with any manner.Therefore, the following examples are intended to be merely illustrative and not limiting of the present disclosure in any way.

[0069] The method of the preparation embodiment of the present disclosure includes:

[0070] Embodiment I1. A method for preparing a composition as described in the Summary of the Invention, wherein the encapsulated bixlozone is encapsulated with a material selected from synthetic polymers, polyurea, polyurethane, polyacrylate, polyamide, polyvinyl alcohol, polyvinylpyrrolidone, semi-synthetic materials, modified cellulose, modified starch derivatives, natural materials, gum arabic, agar, dextrin, alginic acid, alginates, biodegradable natural polymers, collagen, polysaccharides, starch, dextrin, wax, chitosan, alginate, cellulose, gelatin, derivatives thereof, and combinations thereof.

[0071] Embodiment I2. A method of preparing a composition according to embodiment I1, wherein the encapsulated bixlozone is encapsulated with a material selected from polyurea, biodegradable natural polymers, chitosan, wax, alginate, cellulose, gelatin, and combinations thereof.

[0072] Embodiment I3. A method of preparing a composition according to embodiment I1, wherein the encapsulated bixlozone is encapsulated in a synthetic polymer.

[0073] Embodiment I4. A method of preparing a composition according to embodiment I3, wherein the encapsulated bixlozone is encapsulated in polyurea.

[0074] Embodiment J1. A method of preparing a composition described in the Summary of the Invention, further comprising encapsulating an additional active ingredient prior to forming the mixture.

[0075] Embodiment K1. A method of preparing a composition as described in the Summary of the Invention, wherein the additional active ingredient is encapsulated with a material selected from synthetic polymers, polyurea, polyurethane, polyacrylate, polyamide, polyvinyl alcohol, polyvinylpyrrolidone, semi-synthetic materials, modified cellulose, modified starch derivatives, natural materials, gum arabic, agar, dextrin, alginic acid, alginates, biodegradable natural polymers, collagen, polysaccharides, starch, dextrin, wax, chitosan, alginate, cellulose, gelatin, derivatives thereof, and combinations thereof.

[0076] Embodiment K2. A method of preparing a composition described in embodiment K1, wherein the additional active ingredient is encapsulated with a material selected from polyurea, biodegradable natural polymers, chitosan, wax, alginate, cellulose, gelatin, and combinations thereof.

[0077] Embodiment K3. A method of preparing a composition according to embodiment K1, wherein the additional active ingredient is encapsulated in a synthetic polymer.

[0078] Embodiment K4. A method of preparing a composition according to embodiment K3, wherein the additional active ingredient is encapsulated in polyurea.

[0079] Embodiment L1. A method of preparing a composition as described in the Summary of the Invention, wherein the encapsulated bixlozone is encapsulated separately from any additional active ingredients.

[0080] Embodiment L2. A method of preparing a composition described in the Summary of the Invention, wherein the bixlozone and additional active ingredient are co-encapsulated.

[0081] Embodiment L3. A method of preparing a composition according to embodiment L2, wherein the bixlozone and the additional active ingredient are co-encapsulated within the same capsule.

[0082] Embodiment L4. A method of preparing a composition according to embodiment L2, wherein the bixlozone and the additional active ingredient are co-encapsulated in a mixture of different capsules.

[0083] The composition embodiment of the present disclosure can be combined with the method of controlling undesirable vegetation of the present disclosure in any way.Similarly, the method of preparation embodiment of the present disclosure can be combined with the method of controlling undesirable vegetation of the present disclosure in any way.Similarly, the method of controlling undesirable vegetation of the present disclosure can be combined with any way.Therefore, the following examples are merely considered as examples and do not limit the present disclosure in any way.

[0084] An embodiment method of controlling undesirable vegetation of the present disclosure includes:

[0085] Embodiment M1. A method for controlling undesirable vegetation as described in the Summary of the Invention, wherein the undesirable vegetation comprises at least one herbicide-resistant or herbicide-tolerant weed species.

[0086] Embodiment M2. A method for controlling undesirable vegetation as described in the Summary of the Invention, wherein the undesirable vegetation comprises broadleaf weeds or grass weeds.

[0087] Embodiment M3. The undesirable vegetation is Abutilon theophrasti (ABUTH), Acalypha virginica (ACCVI), Alopecurus myosuroides (ALOMY), Amaranthus retroflexus (AMARE), Ambrosia artemisiifolia (AMBEL), Anagallis arvensis (ANGAR), Apera spica-venti (APESV), Arrhenatherum elatius (ARREB), Calystegia sepium (CAGSE), Capsella bursa-pastoris (CAPSELLA bursa-pastoris (CAPBP), Centaurea cyanus (CENCY), Chenopodium album (CHEAL), Chenopodium hybridum (CHEHY), Chenopodium polyspermum (CHEPO), Convolvulus arvensis (CONAR), Cynodon dactylon (CYNDA), Cyperus difformis (CYPDI), Cyperus iria (CYPIR), Datura stramonium (DATST), Daucus carota carota (DAUCA), Descurainia sophia (DESSO), Digitaria sanguinalis (DIGSA), Echinochloa crus-galli (ECHCG), Echinochloa coronam (Echinochloacolonum (ECHCO), Fumaria officinalis (FUMOF), Galium aparine (GALAP), Galinsoga quadriradiata (GASCI), Geranium dissectum (GERDI), Geranium mole (GERMO), Geranium pusillum (GERPU), Hibiscus trionum (HIBTR), Lamium amplexicaule (LAMAM), Lamium purpureum (LAMPU), Buglossoides arvensis (LITAR), Lolium multiflorum multiflorum (LOLMU), Lolium perenne (LOLPE), Lolium rigidum (LOLRI), Matricaria chamomilla (MATCH), Tripleurospermum inodorum (MATIN), Mercurialis annua (MERAN), Panicum dichotomiflorum (PANDI), Panicum miliaceum (PANMI), Papaver rhoeas (PAPRH), Phalaris minor (PHAMI), Poa annua (POAAN), Polygonum aviculare aviculare) (POLAV), Fallopia convolvulus (POLCO), Persicaria hydropiper (POLHY), Persicaria lapasifolia (Persicarialapathifolia (POLLA), Persicaria maculosa (POLPE), Portulaca oleracea (POROL), Potentilla tridentate (PTLTR), Senecio vulgaris (SENVU), Setaria pumila (SETPU), Setaria viridis (SETVI), Solanum nigrum (SOLNI), Sorghum halepense (SORHA), Stellaria media (STEME), Trifolium incarnatum (TRFIN), Veronica arvensis (Veronica arvensis (VERAR), Veronica hederifolia (VERHE), Veronica persica (VERPE), Viola arvensis (VIOAR) and Xanthium strumarium (XANST), and combinations thereof.

[0088] Embodiment M4. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Abutilon theophrasti (ABUTH).

[0089] Embodiment M5. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Acalypha virginica (ACCVI).

[0090] Embodiment M6. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Alopecurus myosuroides (ALOMY).

[0091] Embodiment M7. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Amaranthus retroflexus (AMARE).

[0092] Embodiment M8. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Ambrosia artemisiifolia (AMBEL).

[0093] Embodiment M9. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Anagallis arvensis (ANGAR).

[0094] Embodiment M10. A method of controlling undesirable vegetation according to embodiment M3, wherein the undesirable vegetation is Apera spica-venti (APESV).

[0095] Embodiment M11. A method of controlling undesirable vegetation according to embodiment M3, wherein the undesirable vegetation is Arrhenatherum elatius (ARREB).

[0096] Embodiment M12. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Calystegia sepium (CAGSE).

[0097] Embodiment M13. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Capsella bursa-pastoris (CAPBP).

[0098] Embodiment M14. A method of controlling undesirable vegetation according to embodiment M3, wherein the undesirable vegetation is Centaurea cyanus (CENCY).

[0099] Embodiment M15. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Chenopodium album (CHEAL).

[0100] Embodiment M16. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Chenopodium hybridum (CHEHY).

[0101] Embodiment M17. A method of controlling undesirable vegetation according to embodiment M3, wherein the undesirable vegetation is Chenopodium polyspermum (CHEPO).

[0102] Embodiment M18. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Convolvulus arvensis (CONAR).

[0103] Embodiment M19. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Cynodon dactylon (CYNDA).

[0104] Embodiment M20. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Cyperus difformis (CYPDI).

[0105] Embodiment M21. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Cyperus iria (CYPIR).

[0106] Embodiment M22. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Datura stramonium (DATST).

[0107] Embodiment M23. The method of controlling undesirable vegetation according to embodiment M3, wherein the undesirable vegetation is Daucus carota (DAUCA).

[0108] Embodiment M24. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Descurainia sophia (DESSO).

[0109] Embodiment M25. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Digitaria sanguinalis (DIGSA).

[0110] Embodiment M26. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Echinochloa crus-galli (ECHCG).

[0111] Embodiment M27. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Echinochloa colonum (ECHCO).

[0112] Embodiment M28. The method of controlling undesirable vegetation according to embodiment M3, wherein the undesirable vegetation is Fumaria officinalis (FUMOF).

[0113] Embodiment M29. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Galium aparine (GALAP).

[0114] Embodiment M30. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Galinsoga quadriradiata (GASCI).

[0115] Embodiment M31. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Geranium dissectum (GERDI).

[0116] Embodiment M32. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is geranium mole (GERMO).

[0117] Embodiment M33. The method of controlling undesirable vegetation according to embodiment M3, wherein the undesirable vegetation is Geranium pusillum (GERPU).

[0118] Embodiment M34. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Hibiscus trionum (HIBTR).

[0119] Embodiment M35. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Lamium amplexicaule (LAMAM).

[0120] Embodiment M36. The method of controlling undesirable vegetation according to embodiment M3, wherein the undesirable vegetation is Lamium purpureum (LAMPU).

[0121] Embodiment M37. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Buglossoides arvensis (LITAR).

[0122] Embodiment M38. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Lolium multiflorum (LOLMU).

[0123] Embodiment M39. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Lolium perenne (LOLPE).

[0124] Embodiment M40. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Lolium rigidum (LOLRI).

[0125] Embodiment M41. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Matricaria chamomilla (MATCH).

[0126] Embodiment M42. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Tripleurospermum inodorum (MATIN).

[0127] Embodiment M43. The method of controlling undesirable vegetation according to embodiment M3, wherein the undesirable vegetation is Mercurialis annua (MERAN).

[0128] Embodiment M44. A method for controlling undesirable vegetation according to embodiment M3, wherein the undesirable vegetation is Panicum dichotomiflorum (PANDI).

[0129] Embodiment M45. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Panicum miliaceum (PANMI).

[0130] Embodiment M46. A method for controlling undesirable vegetation according to embodiment M3, wherein the undesirable vegetation is Papaver rhoeas (PAPRH).

[0131] Embodiment M47. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Phalaris minor (PHAMI).

[0132] Embodiment M48. A method of controlling undesirable vegetation according to embodiment M3, wherein the undesirable vegetation is Poa annua (POAAN).

[0133] Embodiment M49. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Polygonum aviculare (POLAV).

[0134] Embodiment M50. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Fallopia convolvulus (POLCO).

[0135] Embodiment M51. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Persicaria hydropiper (POLHY).

[0136] Embodiment M52. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Persicaria lapathifolia (POLLA).

[0137] Embodiment M53. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Persicaria maculosa (POLPE).

[0138] Embodiment M54. A method for controlling undesirable vegetation according to embodiment M3, wherein the undesirable vegetation is Portulaca oleracea (POROL).

[0139] Embodiment M55. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Potentilla tridentate (PTLTR).

[0140] Embodiment M56. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Senecio vulgaris (SENVU).

[0141] Embodiment M57. The method of controlling undesirable vegetation according to embodiment M3, wherein the undesirable vegetation is Setaria pumila (SETPU).

[0142] Embodiment M58. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Setaria viridis (SETVI).

[0143] Embodiment M59. The method of controlling undesirable vegetation according to embodiment M3, wherein the undesirable vegetation is Solanum nigrum (SOLNI).

[0144] Embodiment M60. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Sorghum halepense (SORHA).

[0145] Embodiment M61. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Stellaria media (STEME).

[0146] Embodiment M62. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Trifolium incarnatum (TRFIN).

[0147] Embodiment M63. The method of controlling undesirable vegetation according to embodiment M3, wherein the undesirable vegetation is Veronica arvensis (VERAR).

[0148] Embodiment M64. The method of controlling undesirable vegetation according to embodiment M3, wherein the undesirable vegetation is Veronica hederifolia (VERHE).

[0149] Embodiment M65. The method of controlling undesirable vegetation of embodiment M3, wherein the undesirable vegetation is Veronica persica (VERPE).

[0150] Embodiment M66. The method of controlling undesirable vegetation according to embodiment M3, wherein the undesirable vegetation is Viola arvensis (VIOAR).

[0151] Embodiment M67. The method of controlling undesirable vegetation according to embodiment M3, wherein the undesirable vegetation is Xanthium strumarium (XANST).

[0152] Embodiment M68. The undesirable vegetation is annual longgrass, annual ryegrass (Lolium rigidum), ball medic (Medicago spp.), barley grass (Hordeum murinum), bedstraw (Galium tricornutum), morning glory, bifora (Bifora testiculata), blackgrass, nightshade, broadleaf signalgrass, bromegrass (Bromus spp.), Canada thistle, Cape weed (Arctotheca calendula), brome grass, chickweed (Stellaria media), cocklebur (Xanthium pensylvanicum), ragweed, corn poppy, double ghee (Emex australis), field violet, ragweed (Conyza bonariensis), foxtail, burdock (Fumaria spp), goosegrass, foxtail grass, guineagrass, broomweed, herbicide-resistant blackgrass, artemisia, and burdock (Sisymbrium orientalis) orientale), Italian ryegrass, common chickweed (Gnaphalium luteoalbum), white morning glory, western sorghum (Sorghum halepense), dwarf grass, American loosestrife (Lythrum hyssopifolia), little-seed cannygrass, morning glory, purple grass (Echium plantagineum), American sedge, false sedge (Phalaris paradoxa), morning glory, thorny lettuce (Lactuca serriola) serriola), American sedge, quackgrass, yellow mallow (Modiola caroliniana), redroot pigweed, dog poppy (Papaver hybridum), serradella, sorghum, shepherd's purse, silky windgrass, miscanthus (Vulpia bromoides), sowweed (Sonchus oleraceus), and clover (Trifolium spp.), sunflower (as a weed in potato), wild chickpea, broad bean, snow pea, lentil, lupine and vetch, bindweed (Polygonum convolvulus), field mustard (Brassica kaber), oat (Avena fatua), wild point setia, wild radish (Raphanus raphanistrum), oilseed rape (Rapistrum rugosum, Brassica tournefortii), willow (Polygonum aviculare), golden hawkweed, corn nut (Cyperus esculentus), esculentus).

[0153] Embodiment M69. The method of embodiment M68, wherein the undesirable vegetation is selected from wild radish (Raphanus raphanistrum), velvetleaf, white morning glory, cocklebur, and burdock.

[0154] Embodiment M70. The method of embodiment M68, wherein the undesirable vegetation is wild radish (Raphanus raphanistrum).

[0155] Embodiment N1. A method for controlling undesirable vegetation as described in the Summary of the Invention, wherein the composition is applied at a stage selected from pre-emergence, post-emergence, and combinations thereof.

[0156] Embodiment N2. A method for controlling undesirable vegetation according to embodiment N1, wherein the composition is applied pre-emergence.

[0157] Embodiment N3. A method for controlling undesirable vegetation according to embodiment N1, wherein the composition is applied post-emergence.

[0158] Embodiment N4. A method for controlling undesirable vegetation according to embodiment N1, wherein the composition is applied pre-emergence and post-emergence.

[0159] Generally, compositions according to the present disclosure comprise an effective amount of encapsulated and unencapsulated vixlozone. An effective amount of encapsulated and unencapsulated vixlozone is any amount capable of controlling harmful plants while providing acceptable safety in the absence of a safener. The effectiveness of the composition used in a method for controlling harmful plants will depend on various factors, such as the mode of application, the harmful plants to be controlled, the useful plants to be protected, and the time of application. The method of use of the effective composition can be easily determined by those skilled in the art using well-known principles.

[0160] In many embodiments, the encapsulated and unencapsulated bixlosone are present and / or applied in a ratio of encapsulated bixlosone to unencapsulated bixlosone that is effective. The ratio can be a weight ratio, a molar ratio, a rate ratio, or a volume ratio. The ratio is preferably a rate ratio. As used herein, an effective application rate is one that is effective against target weeds and safe for the crop.

[0161] In some embodiments, the encapsulated bixlozone is at about 1 g / ha, about 10 g / ha, about 50 g / ha, about 100 g / ha, about 200 g / ha, about 300 g / ha, about 400 g / ha, about 500 g / ha, about 600 g / ha, about 700 g / ha, about 800 g / ha, about 900 g / ha, about 1000 g / ha, about 1100 g / ha, about 1200 g / ha, about 1300 g / ha, Approx. 1400g / ha, approx. 1500g / ha, approx. 1600g / ha, approx. 1700g / ha, approx. 1800g / ha, approx. 1900g / ha, approx. 2000g / ha, approx. 2100g / ha, approx. 2200 g / ha, approx. 2300g / ha, approx. 2400g / ha, approx. 2500g / ha, approx. 2600g / ha, approx. 2700g / ha, approx. 2800g / ha, approx. 2900g / ha, approx. 3000g / ha is over about 3000g / ha to about 10g / ha, about 50g / ha, about 100g / ha, about 200g / ha, about 300g / ha, about 400g / ha, about 500g / ha, about 600g / ha, about 700g / ha, about 800g / ha, about 900g / ha, about 1000g / ha, about 1100g / ha, about 1200g / ha, about 1300g / ha, about 1400g / ha, about 1500g / ha, and about 1600 g / ha, about 1700 g / ha, about 1800 g / ha, about 1900 g / ha, about 2000 g / ha, about 2100 g / ha, about 2200 g / ha, about 2300 g / ha, about 2400 g / ha, about 2500 g / ha, about 2600 g / ha, about 2700 g / ha, about 2800 g / ha, about 2900 g / ha, about 3000 g / ha or greater than about 3000 g / ha, although higher and lower doses may also provide sufficient control.

[0162] In some embodiments, the unencapsulated bixlozone is at about 1 g / ha, about 10 g / ha, about 50 g / ha, about 100 g / ha, about 200 g / ha, about 300 g / ha, about 400 g / ha, about 500 g / ha, about 600 g / ha, about 700 g / ha, about 800 g / ha, about 900 g / ha, about 1000 g / ha, about 1100 g / ha, about 1200 g / ha, about 1300 g / ha , about 1400g / ha, about 1500g / ha, about 1600g / ha, about 1700g / ha, about 1800g / ha, about 1900g / ha, about 2000g / ha, about 2100g / ha, about 220 0g / ha, approx. 2300g / ha, approx. 2400g / ha, approx. 2500g / ha, approx. 2600g / ha, approx. 2700g / ha, approx. 2800g / ha, approx. 2900g / ha, approx. 3000g / ha Or over about 3000g / ha to about 10g / ha, about 50g / ha, about 100g / ha, about 200g / ha, about 300g / ha, about 400g / ha, about 500g / ha, about 600g / ha, about 700g / ha, about 800g / ha, about 900g / ha, about 1000g / ha, about 1100g / ha, about 1200g / ha, about 1300g / ha, about 1400g / ha, about 1500g / ha, Amounts of about 1600 g / ha, about 1700 g / ha, about 1800 g / ha, about 1900 g / ha, about 2000 g / ha, about 2100 g / ha, about 2200 g / ha, about 2300 g / ha, about 2400 g / ha, about 2500 g / ha, about 2600 g / ha, about 2700 g / ha, about 2800 g / ha, about 2900 g / ha, about 3000 g / ha or greater than about 3000 g / ha are used, however, higher and lower doses may also provide sufficient control.

[0163] The application rate of the composition will vary depending on the prevailing conditions, such as the target weed, the degree of infestation, weather conditions, soil conditions, crop species, application method and application time. The compositions containing the active compounds can be applied in the form in which they are formulated. In the practice of the present disclosure, for example, when a formulator prepares a formulation, the application rates of encapsulated and non-encapsulated vixrozone can be varied independently of each other, provided that each of the components is applied within the disclosed limits of the present disclosure.

[0164] The composition according to the present disclosure can be any suitable form of pesticide composition known in the art. A particularly preferred formulation of the composition according to the present disclosure is a mixture (ZC) of a suspension concentrate (SC) and a capsule suspension concentrate (CS) formulation. The acronym "SC" refers to a suspension concentrate (a stable suspension of an active ingredient with water as a fluid), and "ZC" refers to a mixed formulation of CS and SC (a stable suspension of a capsule and an active ingredient in a fluid, usually intended to be diluted with water before use).

[0165] The pesticide composition can be applied in various combinations of two active compounds. For example, they can be applied in the form of a single "premix" or in the form of a combined spray mixture, such as a "tank mix", composed of separate formulations of active compounds. Therefore, to be used in combination, the two active compounds do not need to be applied in a physically combined form or even simultaneously; that is, the components can be applied separately and / or sequentially, provided that the application of the second active compound is carried out within a reasonable period of time from the application of the first active compound. The combined effect occurs regardless of the time when the two active compounds are applied simultaneously. Thus, for example, when the second active compound is applied, as long as the previously applied active compound is still present on the harmful plant to be controlled or in the soil surrounding the harmful plant to be controlled, and as long as the weight ratio of the available active compounds is within the ratio range provided herein, the physical combination of the two active compounds can be applied, or one can be applied before the other. The order in which the individual components, encapsulated and unencapsulated vixlozone, are applied is not critical.Similarly, any combination of active ingredients can be applied for the pre- or post-emergence control of harmful plants, e.g., weeds in crops of useful plants.

[0166] Compositions according to the present disclosure may be formulated using additional suitable formulation ingredients known in the art. By way of non-limiting example, compositions according to the present disclosure may be formulated using known adjuvants, adjuvants, diluents, solvents, dispersants, surfactants, protective colloids, thickeners, penetrants, stabilizers, sequestering agents, anti-caking agents, colorants, pigments, corrosion inhibitors, biocides, antifoaming agents, antifreeze agents, rheology modifiers, and combinations thereof.

[0167] As used herein, the term surfactant refers to an agriculturally acceptable material that provides emulsifying, stabilizing, spreading, wetting, dispersing, or other surface-modifying properties. Examples of suitable surfactants include lignin sulfonates, fatty acid sulfonates (e.g., lauryl sulfonate), condensation products of formaldehyde and naphthalene sulfonate, alkylaryl sulfonates, ethoxylated alkylphenols, and ethoxylated fatty alcohols. Other known surfactants used with herbicides are also acceptable.

[0168] Suitable diluents can be added during the formulation process, after the formulation process (e.g., by the user—a farmer or custom applicator), or both. The term diluent includes all liquid and solid agriculturally acceptable materials, including carriers, that can be added to herbicides to make them suitable for application or commercial use, including solvents, emulsifiers, and dispersants. Examples of suitable solid diluents or carriers are aluminum silicate, talc, calcined magnesia, diatomaceous earth, tricalcium phosphate, cork powder, absorbent carbon black, chalk, silica, and clays such as kaolin and bentonite. Examples of suitable liquid diluents include water, organic solvents (e.g., acetophenone, cyclohexanone, isophorone, toluene, xylene, petroleum distillates), amines (e.g., ethanolamine, dimethylformamide), and mineral, animal, and vegetable oils (used alone or in combination).

[0169] Compositions according to the present disclosure can also be formulated with further suitable additional active ingredients known in the art. Additional herbicides can be utilized if extended spectrum control or prevention of resistance accumulation is desired.

[0170] Examples of additional active ingredients are acetochlor, acifluorfen and its sodium salt, aclonifen, acrolein (2-propenal), alachlor, alloxydim, ametryn, amicarbazone, amidosulfuron, aminocyclopyrachlor and its esters (e.g., methyl, ethyl) and salts (e.g., sodium, potassium), aminopyralid, amitrole, ammonium sulfamate, anilofos, asulam, atrazine, azimsulfuron, beflubutamid, beflubutamid-M, benazolin, benazolin-ethyl, bencal Bazone, Benfluralin, Benfuresate, Benquinotrione, Bensulfuron-methyl, Bensulide, Bentazon, Benzobicyclon, Benzofenap, Bicyclopyrone, Bifenox, Viranafos, Bipyrazone, Bispyribac and its sodium salt, Broclozone, Bromacil, Bromobutide, Bromofenoxime, Bromoxynil, Bromoxynil octanoate, Butachlor, Butafenacil, Butamifos, Butralin, Butroxydim, Butyrate, Cafenstrole, Carbetamide, Carfentrazone-ethyl, Catechin, Chlomethrin Xifene, chloramben, chlorbromuron, chlorflurenol-methyl, chloridazon, chlorimuron-ethyl, chlorotoluron, chlorpropham, chlorsulfuron, chlorthal-dimethyl, chlorthiamid, cinidon-ethyl, cinmethylin, cinosulfuron, clasifos, clefoxydim, clethodim, clodinafop-propargyl, clomazone, clomeprop, clopyralid, clopyralid-olamine, chloransulam-methyl, cumyluron, cyanazine, cycloate, cyclopyranyl, cyclopyrimorate, cyclosulfam ron, cycloxydim, cyhalofop-butyl, sipirafluon, 2,4-D and its butotyl, butyl, isoctyl and isopropyl esters and its dimethylammonium, diolamine and trolamine salts, dymron, dalapon, dalapon-sodium, dazomet, 2,4-DB and its dimethylammonium, potassium and sodium salts, desmedipham, desmetrin, dicamba and its diglycolammonium, dimethylammonium, potassium and sodium salts, dichlobenil, dichlorprop, diclofop-methyl,Diclosulam, difenzoquat methyl sulfate, diflufenican, diflufenzopyr, dimefron, dimesulfazate, dimepiperate, dimesulfazate, dimethachlor, dimethametrin, dimethenamid, dimethenamid-P, dimethipine, dimethylarsinic acid and its sodium salt, dinitramine, dinoterb, dioxopyritrion, diphenamide, diquat dibromide, dithiopyr, diuron, DNOC, endothal, EPTC, epirifenacil, esprocarb, ethalfluralin, ethametsurfuron-methyl, etiodin, etof Mesate, ethoxyfen, ethoxysulfuron, etobenzanide, fenoxaprop-ethyl, fenoxaprop-P-ethyl, fenoxasulfone, fenpyrazone, fenquinotrione, fentrazamide, fenuron, fenuron-TCA, flamprop-methyl, flamprop-M-isopropyl, flamprop-M-methyl, flazasulfuron, florasulam, fluazifop-butyl, fluazifop-P-butyl, fluazolate, flucarbazone, flucetosulfuron, fluchloralin, fluchloraminopyr, flufenacet, Flufenoximacil, flufenpyr, flufenpyr-ethyl, flumetsulam, flumiclorac-pentyl, flumioxazin, fluometuron, fluoroglycofen-ethyl, flupoxam, flupyrsulfuron-methyl and its sodium salt, flurenol, flurenol-butyl, fluridone, flurochloridone, fluroxypyr, flurtamone, flusulfinam, fluthiacet-methyl, fomesafen, foramsulfuron, fosamine-ammonium, glufosinate, glufosinate-ammonium, L-glufosinate-ammonium ammonium, glufosinate-P, glyphosate and its salts such as ammonium, isopropylammonium, potassium, sodium (including sesquisodium) and trimesium (alternatively called sulfosate), halaxifen, halaxifen-methyl, halosulfuron-methyl, haloxyfop-ethotyl, haloxyfop-methyl, hexazinone, hydantocidin, icaforin, imazamethabenz-methyl, imazamox, imazapic, imazapyr, imazaquin, imazaquin-ammonium, imazethapyr, imazethapyr-ammonium,Imazosulfuron, indanofan, indaziflam, indolauxipyr, iofensulfuron, iodosulfuron-methyl, ioxynil, ioxynil octanoate, ioxynil-sodium, ipfencarbazone, iptriazopyride, isoproturon, isouron, isoxaben, isoxaflutole, isoxachlorthor, lactofen, lancotrione, lenacil, linuron, maleic hydrazide, MCPA and its salts (e.g., MCPA-dimethylammonium, MCPA-potassium and MCPA-sodium, estheryl) esters (e.g., MCPA-2-ethylhexyl, MCPA-butotyl) and thioesters (e.g., MCPA-thioethyl), MCPB and its salts (e.g., MCPB-sodium) and esters (e.g., MCPB-ethyl), mecoprop, mecoprop-P, mefenacet, mefluidide, mesosulfuron-methyl, mesotrione, metam-sodium, metamifop, metamitron, metazachlor, metazosulfuron, methabenzthiazuron, methylarsonic acid and its calcium, monoammonium, monosodium and disodium salts, methiazolinone, Rudaimuron, metobenzuron, metobromuron, metolachlor, S-metolachlor, metoslam, metoxuron, metoproxybicyclon, metribuzin, metsulfuron-methyl, molinate, monolinuron, naproanilide, napropamide, napropamide-M, naptalam, nebron, nicosulfuron, norflurazon, orbencarb, orthosulfamuron, oryzalin, oxadiargyl, oxadiazon, oxasulfuron, oxaziclomefone, oxyfluorfen, paraquat dichloride, pebulate, pelargonic acid, pen Dimethalin, penoxsulam, pentanochlor, pentoxazone, perfluidon, petoxamide, petoxyamide, phenmedipham, picloram, picloram-potassium, picolinafen, pinoxaden, piperophos, pretilachlor, primisulfuron-methyl, prodiamine, profoxydim, prometon, prometryn, propachlor, propanil, propaquizafop, propazine, propham, propisochlor, propoxycarbazone, propyrisulfuron, propyzamide, prosulfocarb, prosulfuron, pyraclonil,Pyraflufen-ethyl, pyrasulfotole, pyrazogyl, pyrazolinate, pyrazoxifen, pyrazosulfuron-ethyl, pyribenzoxim, pyributicarb, pyridate, pyriflubenzoxim, pyriftalid, pyriminobac-methyl, pyrimisulfan, pyrithiobac, pyrithiobac-sodium, pyroxasulfone, piroxsulam, quinclorac, quinmerac, quinoclamine, quizalofop-ethyl, quizalofop-p-ethyl, quizalofop-p-tefuryl, rimisoxafen, rimsulfuron, saflufenacil , Sethoxydim, Siduron, Simazine, Simetryn, Sulcotrione, Sulfentrazone, Sulfometuron-methyl, Sulfosulfuron, 2,3,6-TBA, TCA, TCA-sodium, Tebutam, Tebuthiuron, Tefuryltrione, Tembotrione, Tepraloxydim, Terbacil, Terbumeton, Terbuthylazine, Terbutryn, Tetflupyrrolimet, Thenylchlor, Thiazopyr, Thiencarbazone, Thifensulfuron-methyl, Thiobencarb, Thiafenacil, Thiocarbazil, Tolpyralate, Topramezone, Toral Coxydim, triallate, triafamone, triasulfuron, triaziflam, tribenuron-methyl, triclopyr, triclopyr-butotyl, triclopyr-triethylammonium, tridiphan, trietazine, trifloxysulfuron, trifludimoxazine, trifluralin, triflusulfuron-methyl, tripyrasulfone, tritosulfuron, vernolate, 3-(2-chloro-3,6-difluorophenyl)-4-hydroxy-1-methyl-1,5-naphthyridin-2(1H)-one, 6-chloro-4-(2,7-dimethylphenyl)-4-hydroxy-1-methyl-1,5-naphthyridin-2(1H)-one, N-(2-chloro-6-oxo-1-cyclohexen-1-yl)carbonyl]-1-(4-methoxyphenyl)-2(1H)-quinoxalinone, 2-chloro-N-(1-methyl-1H-tetrazol-5-yl)-6-(trifluoromethyl)-3-pyridinecarboxamide, 7-(3,5-dichloro-4-pyridinyl)-5-(2,2-difluoroethyl)-8-hydroxypyrido[2,3-b]pyrazin-6(5H)-one),4-(2,6-diethyl-4-methylphenyl)-5-hydroxy-2,6-dimethyl-3(2H)-pyridazinone), 5-[[(2,6-difluorophenyl)methoxy]methyl]-4,5-dihydro-5-methyl-3-(3-methyl-2-thienyl)isoxazole (formerly methioxoline), 4-(4-fluorophenyl)-6-[(2-hydroxy-6-oxo-1-cyclohexen-1-yl)carbonyl]-2-methyl-1,2,4-triazine-3,5(2 H,4H)-dione, methyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-5-fluoro-2-pyridinecarboxylate, 2-methyl-3-(methylsulfonyl)-N-(1-methyl-1H-tetrazol-5-yl)-4-(trifluoromethyl)benzamide, and 2-methyl-N-(4-methyl-1,2,5-oxadiazol-3-yl)-3-(methylsulfinyl)-4-(trifluoromethyl)benzamide. Other herbicides include bioherbicides such as Alternaria destruens Simmons, Colletotrichum gloeosporiodes (Penz.) Penz. & Sacc., Drechsiera monoceras (MTB-951), Myrothecium verrucaria (Albertini & Schweinitz) Ditmar:Fries, Phytophthora palmivora (Butl.) Butl., and Puccinia thlaspeos Schub, their environmentally compatible salts, acids, esters, and amides, and combinations thereof.

[0171] Any water-soluble salt is suitable for this formulation. Examples of suitable salts are common inorganic salts. Suitable salts are those that are readily soluble in water and are selected from the group consisting of alkali metal halides, alkaline earth metal halides, ammonium halides, alkali metal sulfates, alkaline earth metal sulfates, ammonium sulfate, alkali metal nitrates, alkaline earth metal nitrates, ammonium nitrate, alkali metal carbonates, and ammonium carbonate. Examples of alkali metal halides include LiCl, LiBr, LiI, NaCl, NaBr, NaI, KF, KCl, KBr, KI, RbF, RbCl, RbBr, and RbI. Examples of alkaline earth metal halides include MgCl, MgBr, MgI, CaCl, CaBr, CaI, SrCl, SrBr, SrI, BaCl, BaBr, and BaI. Examples of ammonium halides include NHF, NHCl, NHCl, and NHCl. Examples of alkali metal sulfates are Li2SO4, Na2SO4, K2SO4, and Rb2SO4. An example of an alkaline earth metal sulfate is MgSO4. Ammonium sulfate is (NH4)2SO4. Examples of alkali metal nitrates include LiNO3, NaNO3, KNO3, and RbNO3. Examples of alkaline earth metal nitrates include Mg(NO3)2, Ca(NO3)2, and Sr(NO3)2. Ammonium nitrate is NH4NO3. Examples of alkali metal carbonates include Na2CO3, K2CO3, and Rb2CO3. Ammonium carbonate is (NH4)2CO3.

[0172] The compositions according to the present disclosure can be used for the selective control of grasses and annual and perennial monocotyledonous and dicotyledonous harmful plants in the presence of useful plants such as maize, soybeans, peas, beans, rapeseed, sugarcane, cassava, pumpkin, potato, vegetables, wheat, rice, and tobacco. The scope of the present invention also includes the control of such harmful plants found in genetically modified useful plants or useful plants selected by classical means to be resistant to bixrozone. Similarly, the compositions can be used to control undesirable harmful plants in plantation crops.

[0173] Without further elaboration, it is believed that one skilled in the art can, using the preceding description, utilize the present invention to its fullest extent. Accordingly, the following examples are to be construed as merely illustrative, and not limiting of the disclosure in any way. [Example]

[0174] The invention is illustrated by the following examples.

[0175] material. In these examples, the following materials are utilized: Reax 88B: Sodium lignosulfonate dispersant. Aromatic 200ND: Highly soluble naphthalene-depleted C 11 aromatic fluid. Kelzan S+: Xanthan gum. Proxel: An antibacterial aqueous solution of 1,2-benzisothiazol-3(2H)-one. HMDA: hexamethylenediamine. PAPI 27: Polymethylene polyphenyl isocyanate containing methylene diphenyl diisocyanate. Supragil MNS: Condensed methylnaphthalene sulfonic acid, sodium salt Xiameter AFE-0100: 30% active silicone emulsion. Formulation 8: EC formulation containing bixlozone 200 g / L + beflubutamide 125 g / L and cloquintocet-mexyl 34.5 g / L. Formulation 5: ZC formulation containing bixlozone 200 g / L + beflubutamide 125 g / L and cloquintocet-mexyl 34.5 g / L; bixlozone encapsulation ratio: 75% SC + 25% CS; beflubutamide 100% CS; cloquintocet as SC. Formulation 6: ZC formulation containing bixlozone 200 g / L + beflubutamide 125 g / L and cloquintocet-mexyl 34.5 g / L; bixlozone encapsulation ratio: 50% SC + 50% CS; beflubutamide 100% CS; cloquintocet as SC. Formulation 7: ZC formulation containing bixlozone 200 g / L + beflubutamide 125 g / L and cloquintocet-mexyl 34.5 g / L; bixlozone encapsulation ratio: 25% SC + 75% CS; beflubutamide 100% CS; cloquintocet as SC. BEF: Beflubutamide FFC: Flufenacet PEN: pendimethalin DFF: Diflufenican MEF: Mefenpyr diethyl safener F4205-11: 375g / ha bixlozone + 300g / ha petoxamid equivalent rate 1.75L / ha F4253-03: 200g / L Cloquintoset-Mexyl SC Adengo Xtra = Isoxaflutole + Thiencarbazone-methyl + Cyprosulfamide, 225 + 90 + 150 g / L SC; 0.44 L / ha application rate is equivalent to 66 g / ha cyprosulfamide safener.

[0176] Example 1. Composition. Separate encapsulated and non-encapsulated compositions were prepared as follows.

[0177] Composition F9600-4 (Bixlozone SC).

[0178] [Table 1]

[0179] Composition Bixlozone ZC.

[0180] [Table 2]

[0181] Example 2. Preparation of component compositions. The above compositions were prepared as follows.

[0182] Bixlozone encapsulation. Approximately 30 parts of Vixlozone were mixed with 12 parts of Aromatic 200ND and heated to approximately 60-65°C until the Vixlozone was completely dissolved in the Aromatic 200ND. Two parts of PAPI 27 were then added. In a separate container, 46 parts of water were mixed with 1.15 parts of Reax 88B and heated to 65°C. The two solutions were combined and mixed to form a stable emulsion. Two parts of a 43% solution of HMDA were then added to the emulsified mass to obtain encapsulated beflubutamide. The solution was then cured at 55°C for four hours. After the reaction was complete, two parts of a 2.0% Kelzan S solution were added to increase the viscosity.

[0183] Preparation of bixlozone for SC formulation The SC formulation was prepared by wet milling bixlozone in a media mill until a particle size D90 of less than 10 microns was achieved.

[0184] Example 3. Wind tunnel testing. The safety of encapsulated and unencapsulated vixlozone to non-target plants was analyzed by wind tunnel testing. The table below shows the observed relative leaf bleaching and cumulative deposition in water (expressed both as a percentage of applied herbicide and as deposited amount). LOQ stands for limit of quantitation.

[0185] [Table 3]

[0186] [Table 4]

[0187] [Table 5]

[0188] This example demonstrates the superior safety of encapsulated bixlozone on non-target plants compared to unencapsulated bixlozone.

[0189] Example 4. Volatility effects of encapsulated and non-encapsulated bixlozone formulations when applied to bare soil. Greenhouse trials were conducted to determine the area of ​​chickweed affected by the volatility of various herbicides at 1000 g ai / ha. Prior to the start of the trial, 7.5 cm pots were filled with Metromix and seeded with chickweed. The chickweed was grown until the pots were completely covered with leaves. Each herbicide treatment was replicated in three separate rings, including three untreated controls. Herbicide treatments were applied to 10 cm pots. 2 Treatments were applied to Matapeak soil in plastic pots. Treatments were applied using compressed air in a truck spray chamber at 280 L / ha (30 gallons per acre) using a TeeJet 8001E nozzle at 275 kpa (40 psi) (SOP#901). Immediately after application, each pot was covered with plastic.

[0190] Once all treatments were applied, the treated pots were transferred to the greenhouse. One treated pot was placed in the center of each chickweed ring, and the plastic cover was then removed. No overhead water was applied to any plants or pots during the test period. Water and fertilizer for maintaining the chickweed were applied by subirrigation. For each chickweed spoke, the measurement (cm) capturing the furthest visual observation of volatility from the center of the spoke (the center of the treated 10 cm pot) was recorded. Evidence of volatility was recorded as bleaching of chickweed leaves. For each ring, eight measurements were taken on each observation day. Data were analyzed at 95% confidence intervals using Minitab statistical software.

[0191] The data from this study are shown in the table below, where DAT stands for days after treatment.

[0192] [Table 6]

[0193] *Values ​​in columns sharing the same letter are not statistically different.

[0194] In this greenhouse test, no cross-contamination was observed, as determined by the complete lack of visible bleaching on any chickweed plants for the untreated control rings. At the first evaluation interval, all herbicide treatments showed signs of volatilization. As the test progressed, the bleached areas became larger for all treatments. For the Bixlozone compositions, F9600-4 (Bixlozone SC) affected the largest area, while Bixlozone ZC volatilized the least at 10 DAT.

[0195] Example 5. Phytotoxicity testing. The phytotoxicity of encapsulated and non-encapsulated bixlozone compositions was evaluated on winter wheat. The compositions were applied pre-emergence and early post-emergence.

[0196] The results of this example are shown in Figures 1-4. The numbers in parentheses indicate the normality of the applied composition. The safeners were determined to have little to no effect compared to the safener-free bixlozone composition. 2wAA means 2 weeks after application, and BBCH21-29 means the tillering stage of the cereal.

[0197] Example 6. Phytotoxicity test. Maximum phytotoxicity from encapsulated and non-encapsulated bixlozone compositions was evaluated on corn, with the compositions applied pre-emergence and post-emergence after sowing.

[0198] The results of this example are shown in Figures 5 and 6. The numbers in brackets indicate the rate of composition applied in g ai / ha.

[0199] Figure 5 shows acceptable phytotoxicity for Bixlozone ZC and F4205-11 at postemergence time points for BBCH 11-12. BBCH11-12 refers to one to two true leaves on the crop. Symptoms observed were primarily leaf bleaching / whitening, with occasional growth stunting at 375 g ai / ha. These symptoms were always transient, and in two of the six trials, there was no significant crop response. Mixtures containing Adengo Xtra (containing cyprosulfamide) showed reduced phytotoxicity. However, no effect was observed with cloquintocet-mexyl.

[0200] Figure 6 shows that unacceptable phytotoxicity was observed for Bixlozone ZC (250 and 375 g ai / ha) and F4205-11 at postemergence time points for BBCH13-15. BBCH13-15 refers to the time point at which the crop had three to five true leaves. The observed symptoms were primarily leaf bleaching / whitening, sometimes accompanied by growth stunting. These symptoms were always transient, even if more persistent compared to the earlier postemergence stage of the crop, and in two of the six tests, there was no significant crop response. Mixtures containing Adengo Xtra (containing cyprosulfamide) showed reduced phytotoxicity, primarily visible at high rates. However, no effect was observed with cloquintocet-mexyl.

Claims

1. (i) encapsulated bixlozone; (ii) unencapsulated bixlozone; (iii) optionally, an additional active ingredient; wherein the composition does not contain a safener.

2. 10. The composition of claim 1, wherein the unencapsulated bixlosone is provided by encapsulated bixlosone that immediately disperses the unencapsulated bixlosone upon dilution.

3. 2. The composition of claim 1, wherein the encapsulated bixlosone and the unencapsulated bixlosone are present in a ratio ranging from about 1:9 to about 9:

1.

4. The composition of any one of claims 1 to 3, wherein the encapsulated bixlosone and the unencapsulated bixlosone are present in a ratio ranging from about 1:3 to about 3:

1.

5. The composition of any one of claims 1 to 4, wherein the encapsulated bixlozone is encapsulated with a material selected from synthetic polymers, polyurea, polyurethane, polyacrylate, polyamide, polyvinyl alcohol, polyvinylpyrrolidone, semi-synthetic materials, modified cellulose, modified starch derivatives, natural materials, gum arabic, agar, dextrin, alginic acid, alginates, biodegradable natural polymers, collagen, polysaccharides, starch, dextrin, wax, chitosan, alginate, cellulose, gelatin, derivatives thereof, and combinations thereof.

6. The composition of any one of claims 1 to 5, wherein the additional active ingredient is selected from beflubutamid, beflubutamid-M, petoxamide, clomazone, and combinations thereof.

7. 7. The composition of any one of claims 1 to 6, wherein the additional active ingredient is encapsulated with a material selected from synthetic polymers, polyurea, polyurethane, polyacrylate, polyamide, polyvinyl alcohol, polyvinylpyrrolidone, semi-synthetic materials, modified cellulose, modified starch derivatives, natural materials, gum arabic, agar, dextrin, alginic acid, alginates, biodegradable natural polymers, collagen, polysaccharides, starch, dextrin, wax, chitosan, alginate, cellulose, gelatin, derivatives thereof, and combinations thereof.

8. 8. The composition of claim 7, wherein the encapsulated bixlosone is encapsulated separately from the additional active ingredient.

9. 9. The composition of any one of claims 1 to 8, further comprising an adjuvant selected from dispersants, surfactants, biocides, antifoaming agents, antifreeze agents, rheology modifiers, wetting agents, solvents, salts, and combinations thereof.

10. The composition of any one of claims 1 to 9, in a form selected from a premix and a tank mix.

11. 1. A method for preparing a composition, comprising: I) encapsulating bixlozone; II) A mixture comprising: (i) the encapsulated bixlozone; (ii) unencapsulated bixlozone; iii) optionally, an additional active ingredient; forming a mixture comprising wherein the composition does not include a safener.

12. 12. The method of claim 11, wherein the encapsulated bixlozone is encapsulated with a material selected from synthetic polymers, polyurea, polyurethane, polyacrylate, polyamide, polyvinyl alcohol, polyvinylpyrrolidone, semi-synthetic materials, modified cellulose, modified starch derivatives, natural materials, gum arabic, agar, dextrin, alginic acid, alginates, biodegradable natural polymers, collagen, polysaccharides, starch, dextrin, wax, chitosan, alginate, cellulose, gelatin, derivatives thereof, and combinations thereof.

13. 13. The method of claim 11 or 12, further comprising encapsulating the additional active ingredient prior to forming the mixture.

14. 14. The method of claim 13, wherein the additional active ingredient is encapsulated with a material selected from synthetic polymers, polyurea, polyurethane, polyacrylate, polyamide, polyvinyl alcohol, polyvinylpyrrolidone, semi-synthetic materials, modified cellulose, modified starch derivatives, natural materials, gum arabic, agar, dextrin, alginic acid, alginates, biodegradable natural polymers, collagen, polysaccharides, starch, dextrin, wax, chitosan, alginate, cellulose, gelatin, derivatives thereof, and combinations thereof.

15. 15. The method of claim 13 or 14, wherein the encapsulated bixlosone is encapsulated separately from the additional active ingredient.

16. 1. A method for controlling undesirable vegetation, comprising: preventing the emergence or growth of said undesirable vegetation; (i) encapsulated bixlozone; (ii) unencapsulated bixlozone; (iii) optionally, an additional active ingredient; applying to said undesirable vegetation or its locus, or to the soil or crop, a composition comprising the formula (I) wherein the composition does not contain a safener.

17. 17. The method of claim 16, wherein the vegetation comprises at least one herbicide-resistant or herbicide-tolerant weed species.

18. 18. The method of claim 16 or 17, wherein the vegetation comprises weeds selected from broadleaf weeds and grass weeds.

19. The vegetation includes Abutilon theophrasti (ABUTH), Acalypha virginica (ACCVI), Alopecurus myosuroides (ALOMY), Amaranthus retroflexus (AMARE), Ambrosia artemisiifolia (AMBEL), Anagallis arvensis (ANGAR), Apera spicaventii (APERA spica-venti (APESV), Arrhenatherum elatius (ARREB), Calystegia sepium (CAGSE), Capsella bursa-pastoris (CAPBP), Centaurea cyanus (CENCY), Chenopodium album (CHEAL), Chenopodium hybridum (CHEHY), Chenopodium polyspermum (CHEHY), Polyspermum (CHEPO), Convolvulus arvensis (CONAR), Cynodon dactylon (CYNDA), Cyperus diffformis (CYPDI), Cyperus iria (CYPIR), Datura stramonium (DATST), Daucus carota (DAUCA), Descurainia sophia (DESSO), Digitalia sanguinaris (Digitaria sanguinalis (DIGSA), Echinochloa crus-galli (ECHCG), Echinochloa coronam (Echinochloacolonum (ECHCO), Fumaria officinalis (FUMOF), Galium aparine (GALAP), Galinsoga quadriradiata (GASCI), Geranium dissectum (GERDI), Geranium mole (GERMO), Geranium pusillum (GERPU), Hibiscus trionum (HIBTR), Lamium amplexicaule (Lamium amplexicaule (LAMAM), Lamium purpureum (LAMPU), Buglossoides arvensis (LITAR), Lolium multiflorum (LOLMU), Lolium perenne (LOLPE), Lolium rigidum (LOLRI), Matricaria chamomilla (MATCH), Tripleurospermum inodrum inodorum (MATIN), Mercurialis annua (MERAN), Panicum dichotomiflorum (PANDI), Panicum miliaceum (PANMI), Papaver rhoeas (PAPRH), Phalaris minor (PHAMI), Poa annua (POAAN), Polygonum aviculare (POLAV), Fallopia convolvulus (Fallopia convolvulus (POLCO), Persicaria hydropiper (POLHY), Persicaria lapasifolia (Persicarialapathifolia (POLLA), Persicaria maculosa (POLPE), Portulaca oleracea (POROL), Potentilla tridentate (PTLTR), Senecio vulgaris (SENVU), Setaria pumila (SETPU), Setaria viridis (SETVI), Solanum nigrum nigrum (SOLNI), Sorghum halepense (SORHA), Stellaria media (STEME), Trifolium incarnatum (TRFIN), Veronica arvensis (VERAR), Veronica hederifolia (VERHE), Veronica persica (VERPE), Viola arvensis (VIOAR), and Xanthum strumarium. strumarium (XANST), and combinations thereof.

20. The method of any one of claims 16 to 18, wherein the composition is applied at a stage selected from pre-emergence, post-emergence and combinations thereof.

21. 20. The method of any one of claims 16 to 19, wherein the off-target crop damage from the composition is approximately the same as the off-target crop damage from the composition further supplemented with a safener.

Images