Sampling instrument

Abstract

It is desired to further improve operability of the sampling device.SOLUTION: The sampling device 10 includes a housing 200, a liquid delivery needle 262, and a stopper 250. The housing chamber 214 of the housing 200 can house the sampling container 30. The stopper 250 restricts the movement of the liquid delivery needle 262 by restraining the liquid delivery needle 262 in the first state. When the stopper 250 is switched from the first state to the second state, the restriction on the movement of the liquid delivery needle 262 is released. By the movement of the liquid delivery needle 262, the lumen 264 of the liquid delivery needle 262 communicates with the inside of the sampling container 30 housed in the housing chamber 214.SELECTED DRAWING: Figure 1

Description

[Technical Field]

[0001] The present disclosure relates to a sampling device for collecting a sampling liquid from a collection target. [Background technology]

[0002] In specimen testing, a bodily fluid such as blood or tissue fluid is sampled from a patient using a sampling device. A known example of this type of sampling device is a syringe-type device that includes a barrel, a puncture needle attached to the tip of the barrel, and a plunger movably inserted into the barrel.

[0003] When sampling blood using a syringe-type device, the operator (user) first inserts the puncture needle through the patient's skin into a blood vessel. Next, the user holds the puncture needle with one hand while pulling the plunger toward the proximal end with the other. This moves the plunger toward the proximal end, causing blood to be drawn into the barrel via the puncture needle. In this way, the plunger is moved by the user's manual manipulation.

[0004] In Japanese Patent Laid-Open Publication No. 11-206742, the applicant has proposed a puncture tool in which a plunger is pushed by a coil spring and moves in the proximal direction when a user presses an operation button, thereby aspirating blood or the like into a barrel. [Prior art documents] [Patent documents]

[0005] [Patent Document 1] Japanese Patent Application Publication No. 11-206742 Summary of the Invention [Problem to be solved by the invention]

[0006] It is desirable to further improve the operability of this type of sampling device.

[0007] The present disclosure aims to solve the above-mentioned problems. [Means for solving the problem]

[0008] (1) A first aspect of the present disclosure is a sampling device for collecting sampling liquid, comprising: a housing having a storage chamber for storing a sampling container whose interior is maintained at negative pressure; and a needle hub connection portion for connecting a needle hub to which a puncture needle is connected; a liquid delivery needle for delivering the sampling liquid to the sampling container stored in the storage chamber; a biasing member for biasing the liquid delivery needle toward the sampling container; and a stopper that can be switched from a first state to a second state, wherein the stopper restrains the liquid delivery needle in the first state, thereby restricting movement of the liquid delivery needle against the biasing force from the biasing member, and releases the liquid delivery needle from the restraint as the state switches from the first state to the second state, and the liquid delivery needle, whose movement restriction has been released, moves so that the inner cavity of the liquid delivery needle is in communication with the interior of the sampling container stored in the storage chamber.

[0009] With this configuration, when the user switches the stopper from the first position to the second position, the liquid delivery needle is urged by the urging member, and the lumen of the liquid delivery needle communicates with the inside of the sampling container. Because the inside of the sampling container is under negative pressure, the sampling liquid is drawn into the inside of the sampling container through the liquid delivery needle. This allows the user to collect the sampling liquid with a simple operation.

[0010] (2) A second aspect of the present disclosure is a sampling device for collecting a sampling liquid, the sampling device comprising: a housing having a storage chamber and a needle hub connection portion for connecting a needle hub to which a puncture needle is connected; a container body having an opening; and a stopper body for closing the opening and maintaining a negative pressure inside the container body, the sampling container being able to be accommodated in the storage chamber; a liquid delivery needle for delivering the sampling liquid to the sampling container accommodated in the storage chamber; a biasing member for biasing the liquid delivery needle toward the sampling container; and a stopper switchable from a first state to a second state. wherein the stopper restrains the liquid delivery needle in the first state, thereby restricting movement of the liquid delivery needle against the biasing force from the biasing member, and releases the liquid delivery needle from the restraint as the state switches from the first state to the second state, and the base end of the liquid delivery needle is located further distal than the distal end surface of the stopper when the stopper is in the first state, and is positioned so as to penetrate the stopper and insert into the interior of the container body as the stopper switches from the first state to the second state.

[0011] With this configuration, the liquid delivery needle is biased by the biasing member, and the base end of the liquid delivery needle penetrates the stopper and is positioned to insert into the container body, so that, as in item (1) above, the sampling liquid is drawn into the sampling container via the liquid delivery needle, allowing the user to collect the sampling liquid with a simple operation.

[0012] (3) A third aspect of the present disclosure is a sampling device for collecting a sampling liquid, comprising: a housing having a storage chamber and a needle hub connection part; a container body having an opening; and a stopper that closes the opening and maintains a negative pressure inside the container body, the sampling container being capable of being stored in the storage chamber; a stopper penetration part that is movable within the housing toward the sampling container and that can penetrate the stopper as it moves; a stopper that can be switched from a first state to a second state; a needle hub that is detachably connected to the needle hub connection part; and a needle provided on the needle hub that is punctured into a sample object to remove the sample from the sample object. and a puncture needle that delivers the sampling liquid to the sampling container through the stopper-penetrating portion, wherein the stopper restricts movement of the stopper-penetrating portion in the first state, and releases the stopper-penetrating portion from restraint as the stopper switches from the first state to the second state, thereby releasing the restriction on the movement of the stopper-penetrating portion, and when the stopper is in the first state, the base end of the stopper-penetrating portion is located further distally than the distal end surface of the stopper, and when the stopper switches from the first state to the second state, it is positioned to penetrate the stopper and insert into the inside of the container body.

[0013] With this configuration, the base end of the stopper piercing portion penetrates the stopper and is positioned to insert into the container body, and as in items (1) and (2) above, the sampling liquid is drawn into the sampling container through the stopper piercing portion, allowing the user to collect the sampling liquid with a simple operation.

[0014] (4) In the sampling device according to any one of the above items (1) to (3), the housing may have a restricting portion for restricting relative movement of the sampling container with respect to the housing.

[0015] With this configuration, the sampling container can be positioned and fixed within the housing chamber, and therefore, by moving the liquid delivery needle or the stopper penetration part by a predetermined amount, it can be moved to a position where sampling liquid can be delivered to the sampling container.

[0016] (5) In the sampling device described in any one of items (1) to (3) above, the stopper may be provided on the housing and may be switched from the first state to the second state by moving in a direction perpendicular to the longitudinal direction of the housing.

[0017] With this configuration, it is easy for the user to switch the stopper from the first state to the second state.

[0018] (6) In the sampling device described in item (1) or (2) above, a sealing material is provided to provide a liquid-tight seal between the outer surface of the liquid delivery needle and the inner surface of the housing, and the sealing material may be an elastic body that elastically deforms when the liquid delivery needle moves as the stopper changes from the first state to the second state.

[0019] With this configuration, a liquid-tight seal can be maintained between the outer surface of the liquid delivery needle and the inner surface of the housing before and after the liquid delivery needle moves.

[0020] (7) In the sampling device described in item (1) or (2) above, the biasing member may be an elastic body that can expand and contract based on elasticity, and may be maintained in a compressed state when the stopper is in the first state, and may expand as the stopper switches from the first state to the second state.

[0021] (8) The sampling device described in item (7) above may further include a pressing member that presses the urging member, the pressing member having an insertion hole through which the liquid delivery needle is inserted, and the stopper may form the first state by restraining the pressing member and form the second state by releasing the pressing member from the restraint.

[0022] With this configuration, it is easy to switch the liquid delivery needle from a state in which its movement is restricted to a state in which its movement is released.

[0023] (9) In the sampling device described in the above item (2) or (3), the container body may be a tubular member having the opening at one end in the longitudinal direction and a closed end at the other end in the longitudinal direction.

[0024] (10) In the sampling device described in item (2) or (3) above, the container body is a syringe having a barrel, a plunger that is movably inserted into the barrel, and a plunger fixing device that positions and fixes the plunger that has moved toward the base end within the barrel, and negative pressure may be created inside the barrel as the plunger moves toward the base end.

[0025] (11) A fourth aspect of the present disclosure is a sampling device for collecting a sampling liquid, comprising: a housing having a storage chamber and a needle hub connection portion; a sampling container having a stopper that maintains a negative pressure inside the container body and that can be stored in the storage chamber; a stopper penetration portion having an end that can liquid-tightly penetrate the stopper; a needle hub that is detachably connected to the needle hub connection portion; and a puncture needle that is attached to the needle hub and that punctures a sample to deliver the sampling liquid from the sample to the sampling container via the stopper penetration portion, wherein the end of the stopper penetration portion is movable within the housing from a non-penetrating position where it is separated from the stopper of the sampling container and does not penetrate the stopper, to a penetrating position where it penetrates the stopper.

[0026] According to this configuration, similar to the above items (1) to (3), the sampling liquid is sucked into the sampling container through the stopper penetration part, which allows the user to collect the sampling liquid with a simple operation. [Effects of the Invention]

[0027] According to the present disclosure, a user can collect a sampling liquid with a simple operation. [Brief explanation of the drawings]

[0028] [Figure 1] FIG. 1 is a schematic side cross-sectional view of a sampling device according to a first embodiment of the present disclosure, viewed from a direction perpendicular to the longitudinal direction. [Figure 2] FIG. 2 is a schematic side cross-sectional view showing a state in which the liquid delivery needle has moved in the proximal direction. [Figure 3] FIG. 3 is a schematic side cross-sectional view showing a state in which blood, which is a sampling liquid, is collected in a sampling container. [Figure 4] FIG. 4 is a schematic cross-sectional side view of a sampling device according to a second embodiment of the present disclosure, viewed from a direction perpendicular to the longitudinal direction. [Figure 5] FIG. 5 is a schematic cross-sectional side view of a sampling container that constitutes the sampling device of FIG. [Figure 6] FIG. 6 is a schematic side cross-sectional view showing a state in which the inside of the sampling container of FIG. 5 is under negative pressure. [Figure 7] FIG. 7 is a schematic side cross-sectional view showing a state in which a plunger fixture is attached to the plunger that constitutes the sampling container of FIG. DETAILED DESCRIPTION OF THE INVENTION

[0029] Below, an example will be given in which the subject to be collected is a patient and blood BL (see Figure 1) is collected as the sampling liquid. However, this is an example to simplify the explanation and make it easier to understand, and the present disclosure is not limited to this example. The subject to be collected may also be a patient animal. The sampling liquid may be lymphatic fluid, tissue fluid, etc. Note that the "user" refers to the operator who operates the sampling device 10 to collect blood.

[0030] In the following first embodiment, the aspect shown in FIG. 1 will be mainly described. The aspect shown in FIG. 1 is an aspect in which the sampling device 10 includes a base kit 20, a sampling container 30, and a puncture needle 40. However, users can obtain the base kit 20, the sampling container 30, and the puncture needle 40 separately. In other words, at the distribution stage, it is not necessary for the sampling device 10 to include all of the base kit 20, the sampling container 30, and the puncture needle 40. In another aspect, the sampling device 10 includes only the base kit 20. In yet another aspect, the sampling device 10 includes the base kit 20 and the sampling container 30. For example, when the sampling device 10 includes only the base kit 20, the user assembles a general-purpose puncture needle and a general-purpose sampling container, which they have obtained separately, into the base kit 20.

[0031] The "tip" refers to the end of each component of the sampling device 10 that faces the patient when the puncture needle 40 is inserted into the patient from whom the sample is to be collected. The "tip direction" refers to the direction toward the patient. The "base end" refers to the end opposite the "tip" of each component, and the "base direction" refers to the direction opposite the tip direction. The "length" refers to the dimension along the longitudinal direction of the housing 200 of each component.

[0032] 1 is a schematic side cross-sectional view of a sampling device 10 according to a first embodiment, viewed from a direction perpendicular to the longitudinal direction. The sampling device 10 includes a base kit 20, a sampling container 30, and a puncture needle 40.

[0033] The base kit 20 in the illustrated example has a housing 200, a stopper penetrating portion 260, and a stopper 250. In the first embodiment, the housing 200 has a cylindrical inner member 202 and a cylindrical outer member 230. The inner member 202 has a main body portion 204 and a needle hub connecting portion 206 that protrudes from the tip of the main body portion 204 in the distal direction. The needle hub connecting portion 206 has a smaller diameter than the main body portion 204.

[0034] The inner member 202 has a needle insertion hole 208, a seal chamber 210, a storage space 212, and a storage chamber 214 inside. The needle insertion hole 208, the seal chamber 210, the storage space 212, and the storage chamber 214 are arranged in this order from the distal end to the proximal end of the inner member 202. The proximal end of the inner member 202 is an open end 216. The inner member 202 further has a slit 218. The slit 218 extends in a direction perpendicular to the longitudinal direction of the inner member 202. The storage space 212 and the storage chamber 214 are separated by the slit 218. The storage space 212 is located further distally than the slit 218, and the slit 218 is located further distally than the storage chamber 214.

[0035] The needle insertion hole 208 extends from the needle hub connection portion 206 to the tip of the main body portion 204. The seal chamber 210 has a diameter slightly larger than the needle insertion hole 208. The storage space 212 has a diameter larger than the needle insertion hole 208. The length of the seal chamber 210 is smaller than the needle insertion hole 208 and the storage space 212. The diameter of the storage space 214 is approximately equal to the diameter of the storage space 212. The length of the storage chamber 214 is larger than the storage space 212.

[0036] The length of the outer member 230 is shorter than that of the inner member 202. The outer member 230 covers the outside of the storage chamber 214 in the inner member 202. In the inner member 202, the needle hub connecting portion 206 and the portion of the main body portion 204 in which the seal chamber 210 and the storage space 212 are formed are exposed from the tip of the outer member 230. The base end of the outer member 230 is an open end 232.

[0037] A restricting portion 220 is provided in the storage chamber 214. The restricting portion 220 has a distal restricting portion 222 provided at the distal end of the storage chamber 214 and a proximal restricting portion 226 provided at the proximal end of the storage chamber 214. In the illustrated example, the distal restricting portion 222 is a protrusion 224 formed on the inner circumferential surface of the storage chamber 214. The protrusion 224 may be, for example, a plurality of protrusions each having a substantially hemispherical shape, or may be a ring-shaped protrusion that is connected in a circle around the inner circumferential surface. The distal restricting portion 222 abuts against the distal end surface of the stopper 340 that constitutes the sampling container 30, thereby restricting movement of the sampling container 30 toward the distal end.

[0038] In the illustrated example, the proximal-end restricting portion 226 is a blocking member 240 that simultaneously blocks the open end 216 of the inner member 202 and the open end 232 of the outer member 230. The blocking member 240 is made of, for example, rubber and has a thick, small-diameter first plug portion 242 and a thin, large-diameter second plug portion 244. The first plug portion 242 fits into the open end 216 of the inner member 202 to block the open end 216. The second plug portion 244 fits into the open end 232 of the outer member 230 to block the open end 232. The distal end surface of the second plug portion 244 abuts against the proximal end surface of the inner member 202. In this state, the distal end surface of the first plug portion 242 abuts against the proximal end of the container body 300 that constitutes the sampling container 30, thereby restricting movement of the sampling container 30 toward the proximal end.

[0039] A recess 234 extending in the proximal direction is formed at the tip of the outer peripheral surface of the outer member 230. A stopper 250 is movably provided on the outer member 230. The stopper 250 has a stopper main body 252 and an input portion 254 extending in the proximal direction from the proximal edge of the stopper main body 252. A portion of the stopper main body 252 is inserted into the slit 218. The input portion 254 faces the recess 234. When a user presses the input portion 254 in a direction perpendicular to the longitudinal direction of the housing 200 (the radial direction of the housing 200), the stopper main body 252 moves in the radial direction of the housing 200. In this way, the stopper 250 is movable in the radial direction of the housing 200 based on the user's operation (application of force). Hereinafter, the state before the stopper 250 moves will be referred to as a first state. The state after the stopper 250 moves will be referred to as a second state. In the first state, a part of the stopper body 252 of the stopper 250 is located at a locked position within the slit 218. In the second state, the stopper body 252 of the stopper 250 is located at an unlocked position where it is exposed to the outside of the slit 218.

[0040] The stopper penetrating portion 260 has a pressing member 270 and a liquid delivery needle 262 supported by the pressing member 270. A biasing force is applied to the liquid delivery needle 262 based on the biasing member 280 applying a biasing force to the pressing member 270. In one aspect, the biasing member 280 is an elastic body 281 that can expand and contract based on its elasticity. In the illustrated example, the elastic body 281 is a coil spring 282. However, the biasing member 280 may be any member that can apply a biasing force to the liquid delivery needle 262, and is not limited to the elastic body 281. Furthermore, the elastic body 281 is not limited to the coil spring 282. The elastic body 281 may be a disc spring or the like.

[0041] The pressing member 270 has a pillar portion 272 and a plate portion 274. An insertion hole 276 is formed in the pillar portion 272 and the plate portion 274. The pillar portion 272, which has a smaller diameter than the plate portion 274, is inserted into the interior of the coil spring 282. The tip of the coil spring 282 abuts against the inner surface of the tip of the storage space 212, and the base end of the coil spring 282 abuts against the tip surface of the plate portion 274. In the first state, when a part of the stopper body 252 of the stopper 250 is in the locked position, the tip surface of the stopper body 252 abuts against the base end surface of the plate portion 274. As a result, the stopper 250 restricts the movement of the plug penetrating portion 260 against the elastic force (biasing force) from the coil spring 282. Therefore, the coil spring 282 is stored in the storage space 212 in a compressed state.

[0042] The liquid delivery needle 262 is a hollow body having an inner cavity 264. The tip of the liquid delivery needle 262 is inserted into the needle insertion hole 208. However, the tip of the liquid delivery needle 262 is not constrained by the inner circumferential surface of the needle insertion hole 208. Therefore, the liquid delivery needle 262 is movable relative to the inner member 202.

[0043] The base end of the liquid delivery needle 262 is a sharp cutting edge, and is exposed from the insertion hole 276 of the presser member 270 and extends toward the sampling container 30. When the stopper 250 is in the first state, the base end of the liquid delivery needle 262 (the base end of the stopper penetrating portion 260) is located further distal than the distal end surface of the stopper 340. That is, in the first state, the stopper penetrating portion 260 does not penetrate the stopper 340. That is, the end (base end) of the stopper penetrating portion 260 is at a non-penetrating position where it is separated from the stopper 340 and does not penetrate the stopper 340.

[0044] The seal chamber 210 is provided with a seal material 290 supported on the inner surface of the seal chamber 210. The liquid delivery needle 262 penetrates the seal material 290. Therefore, the seal material 290 provides a liquid-tight seal between the outer surface of the liquid delivery needle 262 and the inner surface of the seal chamber 210 (the inner surface of the inner member 202 that constitutes the housing 200). As can be seen from this, the liquid delivery needle 262 is supported by the inner surface of the seal chamber 210 via the seal material 290, and is thereby supported by the inner member 202.

[0045] As will be described later, the stopper penetrating portion 260 including the liquid delivery needle 262 moves in the proximal direction within the housing 200 as the stopper 250 changes from the first state to the second state. That is, the end (proximal end) of the stopper penetrating portion 260 moves from a non-penetrating position to a penetrating position where it penetrates the stopper 340. During this movement, it is preferable that the sealant 290 undergoes elastic deformation. That is, it is preferable that the sealant 290 be an elastic body. This prevents the movement of the stopper penetrating portion 260 toward the proximal end from being hindered by the sealant 290.

[0046] The sampling container 30 has a container body 300 and a stopper 340. In the first embodiment, the container body 300 is a tubular member 302 having an opening 301 at one longitudinal end and a closed end at the other longitudinal end. The stopper 340 closes the opening 301. The stopper 340 is made of, for example, rubber. By closing the opening 301 with the stopper 340, the inside of the sampling container 30 is maintained at a negative pressure.

[0047] The sampling container 30 is removably stored in the storage chamber 214. Specifically, the sampling container 30 is inserted into the storage chamber 214 from the open end 232 of the outer member 230 and the open end 216 of the inner member 202. The open end 216 of the inner member 202 and the open end 232 of the outer member 230 are then closed with a closing member 240. The sampling container 30 can be removed from the storage chamber 214 by removing the closing member 240 from the open end 216 of the inner member 202 and the open end 232 of the outer member 230.

[0048] In the illustrated example, the puncture needle 40 has an inner needle 400 and a catheter 420. The proximal end of the inner needle 400 is connected to an inner needle hub 404, and the proximal end of the catheter 420 is connected to a catheter hub 424. In this embodiment, the inner needle hub 404 is the needle hub. However, in another embodiment, the catheter hub 424 can be substituted for the needle hub. An example of another embodiment is when a catheter 420 is already indwelling in a living body. Note that it is not essential that the puncture needle 40 be a double needle consisting of the inner needle 400 and the catheter 420. That is, for example, if a medicinal solution is not administered to a patient from a medical bag after blood collection, the puncture needle 40 may be a single needle. In this case, the single needle hub to which the single needle is connected is the needle hub.

[0049] The inner needle hub 404 has a hollow hub body 406, a first connecting portion 408 protruding from the tip of the hub body 406, and a second connecting portion 410 protruding from the base end of the hub body 406. The base end of the inner needle 400 is inserted into the first connecting portion 408. Based on this insertion, the inner needle 400 is connected to the inner needle hub 404. The needle hub connecting portion 206 of the inner member 202 is inserted into the second connecting portion 410. Based on this insertion, the inner needle hub 404 is connected to the needle hub connecting portion 206.

[0050] The catheter hub 424 has a connection hole 426 and an engagement hole 428 that is continuous with the proximal end of the connection hole 426 and has a larger diameter than the connection hole 426. The proximal end side of the catheter 420 is connected to the connection hole 426. The outer peripheral surface of the first connecting portion 408 of the inner needle hub 404 fits into the inner circumferential surface of the proximal end of the engagement hole 428. As a result, the first connecting portion 408 is releasably and liquid-tightly engaged with the engagement hole 428. The inner needle 400 is passed through the engagement hole 428 and further through the lumen 422 of the catheter 420. The tip of the inner needle 400 is exposed from the tip of the catheter 420.

[0051] Next, blood collection (sampling) using the sampling device 10 will be described.

[0052] First, in the first state before the stopper 250 of the housing 200 moves, the user inserts the sampling container 30 into the storage chamber 214 from the open end 216 (proximal end) of the inner member 202 with the stopper 340 facing the distal end. Note that the interior of the tubular member 302 is maintained at a negative pressure beforehand. The sampling container 30 stops when the distal end surface of the stopper 340 abuts against the distal end restriction portion 222 (protrusion 224). In this state, the closure member 240 closes the open end 216 of the inner member 202 and the open end 232 of the outer member 230. The distal end surface of the first plug portion 242 of the closure member 240 abuts against the proximal end of the container body 300 and serves as the proximal end restriction portion 226. That is, the sampling container 30 is sandwiched between the distal end restriction portion 222 and the proximal end restriction portion 226. This restricts the movement of the sampling container 30 within the storage chamber 214.

[0053] Next, the user connects the second connecting portion 410 of the inner needle hub 404 to the needle hub connecting portion 206. Note that the catheter hub 424 has been attached to the inner needle hub 404 in advance, and the inner needle 400 has been inserted into the lumen 422 of the catheter 420 in advance. Therefore, when the inner needle hub 404 is connected to the needle hub connecting portion 206, the puncture needle 40 is attached to the housing 200. As a result, the lumen 402 of the inner needle 400 communicates with the hollow interior of the inner needle hub 404 and with the lumen 264 of the liquid delivery needle 262 via the needle insertion hole 208.

[0054] Next, the user grasps the outer member 230 with their hand and, while holding the catheter hub 424 with, for example, their index finger, inserts the tip of the inner needle 400 into the patient's body DY. The tips of the inner needle 400 and the catheter 420 are inserted into the blood vessel VE. In this state, the user then switches the stopper 250 from the first state to the second state. Specifically, as shown in FIG. 2, the user pushes the input portion 254 of the stopper 250 in the radial direction of the housing 200. As a result, the input portion 254 is inserted into the recess 234 of the outer member 230, and the stopper body 252 is exposed outside the slit 218. That is, the stopper body 252 moves to the unlock position.

[0055] Here, the user may connect the base kit 20 to the catheter 420 whose tip has been inserted into the blood vessel VE. In this case, the user connects the catheter hub 424 to the needle hub connection portion 206. Next, the user switches the stopper 250 from the first state to the second state in the same manner as described above. This moves the stopper body 252 to the unlocked position.

[0056] As the stopper body 252 moves as described above, the stopper body 252 is no longer in contact with the pressing member 270. In other words, the pressing member 270 is released from the restraint of the stopper body 252. Accordingly, the coil spring 282 expands and presses the plate portion 274 of the pressing member 270 toward the base end. As a result, the pressing member 270 and the liquid delivery needle 262 move toward the base end.

[0057] The cutting edge at the base end of the liquid delivery needle 262 penetrates the stopper 340 and is inserted into the container body 300. This places the lumen 264 of the liquid delivery needle 262 in communication with the interior of the sampling container 30. As the stopper 250 switches from the first state to the second state, the liquid delivery needle 262 moves so that the lumen 264 is in communication with the interior of the sampling container 30 accommodated in the accommodation chamber 214. In other words, the end of the stopper penetration portion 260 (the base end of the liquid delivery needle 262) moves within the housing 200 from a non-penetration position where it is separated from the stopper 340 and does not penetrate the stopper 340, to a penetration position where it penetrates the stopper 340. The base end of the liquid delivery needle 262 penetrates the stopper 340 in a liquid-tight manner.

[0058] As a result, the lumen 402 of the inner needle 400 and the interior of the sampling container 30 communicate with each other via the hollow interior of the inner needle hub 404, the needle insertion hole 208, and the lumen 264 of the liquid delivery needle 262. Furthermore, the sealing material 290 elastically deforms due to its elasticity in response to the above-described movement of the liquid delivery needle 262. Therefore, the sealing material 290 remains supported by the inner surface of the seal chamber 210.

[0059] 3, the blood BL in the blood vessel VE is sucked into the sampling container 30. The blood BL passes through the lumen 402 of the inner needle 400, the hollow interior of the inner needle hub 404, the needle insertion hole 208, and the lumen 264 of the liquid delivery needle 262, and flows into the sampling container 30.

[0060] As can be seen from the above, with the sampling device 10, the user can, through a simple procedure, insert the puncture needle 40 into the patient and switch to a state in which blood BL can be collected via the puncture needle 40. In other words, the user can easily collect blood (sampling).

[0061] After a predetermined amount of blood BL has been collected, the user detaches the catheter hub 424 from the first connecting portion 408 of the inner needle hub 404. This separates the catheter hub 424 and the catheter 420 from the inner needle hub 404. In this state, the user moves the housing 200 toward the proximal end. This causes the inner needle 400 to detach from the patient's blood vessel VE, with the catheter 420 remaining inserted into the patient's blood vessel VE. The inner needle 400 is removed from the lumen 422 of the catheter 420.

[0062] As described above, the sampling container 30 is positioned and fixed by the restricting portion 220, so that the sampling container 30 is prevented from moving within the housing 200 during the above operations.

[0063] The user then removes the closure member 240 from the open end 216 of the inner member 202 and the open end 232 of the outer member 230. This makes it possible to remove the sampling container 30 from the storage chamber 214.

[0064] Although not specifically shown, the user connects a tube extending from a predetermined medical bag to catheter hub 424. This allows a medicinal solution previously contained in the medical bag to be administered to the patient.

[0065] The first embodiment has the following advantages.

[0066] The sampling device 10 includes a stopper 250 that can be switched from a first state to a second state. As shown in FIG. 1, in the first state, the stopper 250 prevents the stopper penetrating portion 260, including the liquid delivery needle 262, from moving toward the sampling container 30 against the biasing force of the biasing member 280. On the other hand, as shown in FIG. 2, the stopper 250 is switched to the second state by a user's operation and moves to the unlocked position. As a result, the stopper penetrating portion 260 is released from the restraint of the stopper 250.

[0067] This releases the restriction on the movement of the stopper penetrating part 260. The stopper penetrating part 260, whose movement restriction has been released, moves so that the lumen 264 of the liquid delivery needle 262 communicates with the inside of the sampling container 30 contained in the storage chamber 214. As a result, sampling liquid (blood BL in the illustrated example) is collected inside the sampling container 30, as shown in FIG.

[0068] In this way, after inserting the puncture needle 40 into the patient, the user can switch the stopper 250 from the first state to the second state with a simple procedure, thereby aspirating the sampling liquid via the puncture needle 40 and the liquid delivery needle 262. In other words, the sampling liquid can be collected with a simple operation.

[0069] As shown in FIGS. 1 to 3, the housing 200 has a restricting portion 220 that restricts the sampling container 30 from moving relative to the housing 200.

[0070] This allows the sampling container 30 to be positioned and fixed within the storage chamber 214 of the housing 200. Therefore, the liquid delivery needle 262, which moves to the base end as the stopper 250 switches from the first state to the second state, is reliably pierced into the stopper 340. In other words, the lumen 264 of the liquid delivery needle 262 is reliably connected to the interior of the sampling container 30.

[0071] The sampling device 10 includes a sealant 290 that provides a liquid-tight seal between the outer surface of the liquid delivery needle 262 and the inner surface of the housing 200. As can be seen by comparing Figures 1 and 2, the sealant 290 easily elastically deforms when the liquid delivery needle 262 moves as the stopper 250 is switched from the first state to the second state. In other words, the sealant 290 is an elastic body.

[0072] Due to the elastic deformation of the sealing material 290 in this way, a liquid-tight seal can be maintained between the outer surface of the liquid supply needle 262 and the inner surface of the housing 200 before and after the liquid supply needle 262 moves.

[0073] The stopper 250 is provided on the housing 200. As shown in Figures 1 and 2, the stopper 250 is switched from the first state to the second state by moving in a direction perpendicular to the longitudinal direction of the housing 200 (in the illustrated example, the radial direction of the housing 200).

[0074] According to this configuration, the user can easily switch the stopper 250 from the first state to the second state with a simple procedure.

[0075] The stopper penetrating portion 260 has a liquid delivery needle 262 and a presser member 270. The presser member 270 has an insertion hole 276. When the liquid delivery needle 262 is inserted into the insertion hole 276, the presser member 270 supports the liquid delivery needle 262. As shown in FIG. 1, the stopper 250 forms a first state by restraining the presser member 270, and restricts the movement of the stopper penetrating portion 260, including the liquid delivery needle 262, toward the base end. On the other hand, as shown in FIG. 2, the stopper 250 releases the presser member 270 from the restraint to form a second state in which the restriction on movement of the stopper penetrating portion 260 is released.

[0076] According to this configuration, it is easy to switch the liquid supply needle 262 from a state in which its movement is restricted to a state in which its movement is released.

[0077] Next, a sampling device 11 according to a second embodiment will be described with reference to Figures 4 to 7. Note that the same components as those shown in Figures 1 to 3 are given the same reference numerals, and detailed description thereof will be omitted.

[0078] In the embodiment shown in Figure 4, the sampling device 11 comprises a base kit 21, a sampling container 31, and a puncture needle 40. However, as with the first embodiment, it is not essential that the sampling device 11 comprise all of the base kit 21, sampling container 31, and puncture needle 40 at the distribution stage. In another embodiment, the sampling device 11 comprises only the base kit 21. In yet another embodiment, the sampling device 11 comprises the base kit 21 and the sampling container 31. For example, if the sampling device 11 comprises only the base kit 21, the user assembles a general-purpose puncture needle and general-purpose sampling container that they have obtained separately into the base kit 21.

[0079] In the base kit 21, the base-end restricting portion 227, like the tip-end restricting portion 222, is a protrusion 224 formed on the inner circumferential surface of the storage chamber 214. The protrusion 224 may be, for example, a plurality of protrusions each having a substantially hemispherical shape, or a ring-shaped protrusion extending around the entire circumference of the inner circumferential surface. The tip-end restricting portion 222 restricts the sampling container 31 from moving toward the tip by contacting the tip surface of the stopper 341. Meanwhile, the base-end restricting portion 227 restricts the sampling container 31 from moving toward the base by contacting the base-end surface of the flange portion 312 of the barrel 306. Note that the tip-end restricting portion 222 may also abut against the tip surface of the barrel 306 instead of the tip surface of the stopper 341. In this case, the sampling container 31 can still be restricted from moving toward the tip.

[0080] Except for the above points, the base kit 21 is configured in the same manner as the base kit 20 of the sampling device 10.

[0081] In the sampling container 31, the container body 300 is a syringe 304. As shown in detail in FIGS. 5 to 7, the syringe 304 has a barrel 306, a plunger 314, and a plunger fixture 320 (see FIG. 7).

[0082] Barrel 306 has a small-diameter inlet portion 308, a large-diameter barrel body 310, and a flange portion 312. Inlet portion 308 is located at the tip of barrel body 310. Inlet portion 308 is hollow, and opening 309 at the tip of inlet portion 308 is closed by plug 341. Barrel body 310 is also hollow, and the interior of barrel body 310 communicates with opening 309. Flange portion 312 protrudes outward in the diameter direction of barrel body 310 at the base end of barrel body 310.

[0083] A gasket 318 is provided at the tip of the plunger 314. The tip of the plunger 314 and the gasket 318 are inserted into the barrel body 310 from the open end, which is the base end of the barrel body 310. In FIG. 5, the gasket 318 is located at the tip of the barrel body 310. In contrast, in FIGS. 4 and 7, the gasket 318 is positioned and fixed closer to the base end of the barrel body 310. As will be described later, in this state, the inside of the inlet portion 308 and the inside of the barrel body 310 are under negative pressure. The plunger 314 has a finger grip 316 at its base end.

[0084] 7, plunger fixture 320 has a distal clip portion 322, a proximal clip portion 324, and a connecting portion 326. Connecting portion 326 is bar-shaped and connects distal clip portion 322 and proximal clip portion 324. The length of connecting portion 326 is slightly shorter than the linear distance from the proximal end of gasket 318 to the distal end of finger hook portion 316. Therefore, when plunger fixture 320 is attached to plunger 314, gasket 318 is located distally of distal clip portion 322, and finger hook portion 316 is located proximally of proximal clip portion 324.

[0085] The distal clip portion 322 and the proximal clip portion 324 are each generally C-shaped. When the generally C-shaped opening of the distal clip portion 322 is pressed against the plunger 314, the distal clip portion 322 expands. This expansion allows the plunger 314 to be inserted into the distal clip portion 322. The same is true for the proximal clip portion 324. As the plunger 314 is inserted into the distal clip portion 322 and the proximal clip portion 324, the plunger fixture 320 is attached to the plunger 314.

[0086] As shown in FIG. 7 , the plunger fixture 320 is attached to the plunger 314 so that the distal end surface of the distal clip portion 322 abuts against the proximal end surface of the barrel 306 (the proximal end surface of the flange portion 312 and the proximal end surface of the barrel body 310). The proximal end surface of the proximal clip portion 324 is attached to the plunger 314 so that it abuts against the distal end surface of the finger hook 316. This positions and fixes the plunger 314. Therefore, even if there is negative pressure between the proximal end surface of the stopper 341 and the distal end surface of the gasket 318 inside the barrel 306, the plunger 314 is prevented from moving distally under atmospheric pressure. In other words, the interior of the barrel 306 is maintained at negative pressure.

[0087] The sampling device 11 shown in FIG. 4 has the same configuration as the sampling device 10 according to the first embodiment (see FIGS. 1 to 3) except for the above.

[0088] Next, blood collection (sampling) using the sampling device 11 will be described.

[0089] As shown in FIG. 5, before use, the syringe 304 has the gasket 318 positioned close to the tip of the barrel body 310. The user first places the stopper 341 in the inlet 308 of the syringe 304. Next, for example, the user grasps the barrel body 310 with their left hand, hooks the fingers of their right hand on the finger grip 316, and pulls the plunger 314 toward the proximal end. This moves the gasket 318 closer to the proximal end of the barrel body 310, as shown in FIG. 6. As a result, negative pressure is generated inside the barrel 306 between the proximal end surface of the stopper 341 and the distal end surface of the gasket 318.

[0090] Next, the user attaches the plunger fixture 320 to the plunger 314 as shown in FIG. 7. That is, as described above, the user inserts the plunger 314 into the distal clip portion 322 and the proximal clip portion 324. The plunger fixture 320 attached to the plunger 314 is movable relative to the plunger 314.

[0091] The plunger 314 moves slightly in the distal direction due to atmospheric pressure. During this movement, the plunger fixture 320, for example, remains stationary relative to the plunger 314. Alternatively, the plunger fixture 320 may move in the distal direction together with the plunger 314.

[0092] As a result of the plunger 314 moving as described above, the plunger fixture 320 is sandwiched between the flange portion 312 of the barrel 306 and the finger hook portion 316, as shown in Fig. 7. That is, the distal end surface of the distal clip portion 322 abuts against the proximal end surface of the barrel 306, and the proximal end surface of the proximal clip portion 324 abuts against the distal end surface of the finger hook portion 316. Based on this, the plunger 314 stops. That is, the inside of the barrel 306 is maintained at a negative pressure.

[0093] Next, the user places the stopper 341 facing the tip, and inserts the sampling container 31 (syringe 304) into the storage chamber 214 from the open end 216 of the inner member 202 and the open end 232 of the outer member 230 shown in FIG.

[0094] The distal end surface of the stopper 341 abuts against the distal end restriction portion 222 (protrusion 224), causing the sampling container 31 to stop. At this time, the flange portion 312 undergoes elastic deformation and passes through the proximal end restriction portion 227. After passing through the proximal end restriction portion 227, the proximal end restriction portion 227 abuts against the outer edge of the proximal end surface of the flange portion 312. As a result, the barrel 306 is sandwiched between the distal end restriction portion 222 and the proximal end restriction portion 227. This restricts the movement of the sampling container 31 within the storage chamber 214.

[0095] Next, the user attaches the puncture needle 40 to the housing 200 by connecting the second connecting portion 410 of the inner needle hub 404 to the needle hub connecting portion 206 of the inner member 202. In this way, the sampling device 11 shown in FIG. 4 is configured.

[0096] The subsequent steps are the same as those in the first embodiment. That is, the user's manipulation moves the stopper body 252 of the stopper 250 to the unlock position, and the pressing member 270 is released from the restraint of the stopper body 252. Accordingly, as in FIG. 2, the coil spring 282 expands, and the pressing member 270 and the liquid delivery needle 262 move toward the base end. That is, the end of the plug penetration portion 260 (the base end of the liquid delivery needle 262) moves within the housing 200 from a non-penetration position where it is separated from the plug 340 and does not penetrate the plug 340, to a penetration position where it penetrates the plug 340. The base end of the liquid delivery needle 262 penetrates the plug 340 in a liquid-tight manner.

[0097] As a result, the base end (cutting edge) of the liquid delivery needle 262 penetrates the stopper 341 and is inserted into the inlet 308 of the barrel 306. Since the inside of the sampling container 31 is under negative pressure, the blood BL in the blood vessel VE is sucked into the barrel 306, as in FIG.

[0098] In this way, in the second embodiment as well, the user can insert the puncture needle 40 into the patient with a simple procedure, and can switch the sampling instrument 11 to a state in which blood BL can be collected.

[0099] After a predetermined amount of blood BL has been collected, the user separates the catheter hub 424 and the catheter 420 from the inner needle hub 404. This causes the base kit 21 to detach from the catheter hub 424, with the catheter 420 remaining inserted into the patient's blood vessel VE. At this point, the base kit 21 contains the sampling container 31 and supports the inner needle 400 via the inner needle hub 404.

[0100] Next, the user removes the syringe 304 with the stopper 341 attached from the storage chamber 214 of the housing 200. As a result, the sampling container 31 is removed from the storage chamber 214.

[0101] Thereafter, the user connects a tube extending from a predetermined medical bag to catheter hub 424. This allows the medicinal solution previously contained in the medical bag to be administered to the patient.

[0102] According to the second embodiment, the same effects as those of the first embodiment can be obtained.

[0103] The present disclosure is not limited to the above disclosure, and various configurations may be adopted without departing from the gist of the present disclosure. [Explanation of symbols]

[0104] 10, 11...Sampling equipment 20, 21...Base kit 30, 31... Sampling container 40... Puncture needle 200...Housing 206...Needle hub connection portion 208... needle insertion hole 214... storage chamber 220: Restriction portion 250: Stopper 260...plug body penetration part 262...liquid transfer needle 270: Pressing member 280: Urging member 281...Elastic body 282...Coil spring 290...Sealing material 302...Pipe member 304...Syringe 306...Barrel 314... Plunger 320... Plunger fixing device 340, 341...plug body 400...inner needle 420...catheter BL...blood

Claims

1. A sampling device for collecting a sampling liquid, a housing having a storage chamber for storing a sampling container whose interior is maintained at a negative pressure, and a needle hub connection portion for connecting a needle hub to which a puncture needle is connected; a liquid delivery needle for delivering the sampling liquid to the sampling container accommodated in the accommodation chamber; a biasing member that biases the liquid delivery needle toward the sampling container; a stopper that is switchable from a first state to a second state; Equipped with the stopper restrains the liquid delivery needle in the first state, thereby restricting movement of the liquid delivery needle against the biasing force from the biasing member, and releases the liquid delivery needle from the restraint as the state switches from the first state to the second state, thereby canceling the restriction on movement of the liquid delivery needle; The sampling device, wherein the liquid delivery needle, whose movement restriction has been released, moves so that the inner cavity of the liquid delivery needle communicates with the inside of the sampling container accommodated in the accommodation chamber.

2. A sampling device for collecting a sampling liquid, a housing having a storage chamber and a needle hub connecting portion for connecting a needle hub to which a puncture needle is connected; a sampling container that can be accommodated in the storage chamber, the sampling container having a container body with an opening and a stopper that closes the opening and maintains a negative pressure inside the container body; a liquid delivery needle for delivering the sampling liquid to the sampling container accommodated in the accommodation chamber; a biasing member that biases the liquid delivery needle toward the sampling container; a stopper that is switchable from a first state to a second state; Equipped with the stopper restrains the liquid delivery needle in the first state, thereby restricting movement of the liquid delivery needle against the biasing force from the biasing member, and releases the liquid delivery needle from the restraint as the state switches from the first state to the second state, thereby canceling the restriction on movement of the liquid delivery needle; A sampling device in which the base end of the liquid delivery needle is positioned further distal than the tip surface of the stopper body when the stopper is in the first state, and as the stopper switches from the first state to the second state, it is positioned to pierce the stopper body and insert into the inside of the container body.

3. A sampling device for collecting a sampling liquid, a housing having a chamber and a needle hub connection; a sampling container that can be accommodated in the storage chamber, the sampling container having a container body with an opening and a stopper that closes the opening and maintains a negative pressure inside the container body; a stopper penetrating portion that is movable within the housing toward the sampling container and that can penetrate the stopper as it moves; a stopper that is switchable from a first state to a second state; a needle hub detachably connected to the needle hub connection portion; a puncture needle provided on the needle hub, puncturing a sample to deliver the sampling liquid from the sample to the sampling container via the stopper penetration portion; Equipped with the stopper restricts movement of the plug-penetrating portion in the first state, and releases the restriction on movement of the plug-penetrating portion by releasing the plug-penetrating portion from restraint as the state switches from the first state to the second state; A sampling device in which the base end of the stopper-penetrating portion is positioned further distal than the tip surface of the stopper when the stopper is in the first state, and is positioned to penetrate the stopper and insert into the interior of the container body as the stopper switches from the first state to the second state.

4. 4. The sampling device according to claim 1, wherein the housing has a restricting portion for restricting relative movement of the sampling container with respect to the housing.

5. A sampling device as described in any one of claims 1 to 3, wherein the stopper is provided on the housing and switches from the first state to the second state by moving in a direction perpendicular to the longitudinal direction of the housing.

6. A sampling device as described in claim 1 or 2, comprising a sealing material that provides a liquid-tight seal between the outer surface of the liquid delivery needle and the inner surface of the housing, the sealing material being an elastic body that elastically deforms when the liquid delivery needle moves as the stopper changes from the first state to the second state.

7. In a sampling device as described in claim 1 or 2, the biasing member is an elastic body that can expand and contract based on its elasticity, is maintained in a compressed state when the stopper is in the first state, and expands as the stopper switches from the first state to the second state.

8. 8. The sampling device according to claim 7, further comprising a pressing member that presses the biasing member, the pressing member having an insertion hole through which the liquid delivery needle is inserted, The stopper forms the first state by constraining the pressing member, and forms the second state by releasing the pressing member from the constrained state.

9. 4. The sampling device according to claim 2, wherein the container body is a tubular member having the opening at one end in the longitudinal direction and a closed end at the other end in the longitudinal direction.

10. 4. A sampling device according to claim 2 or 3, wherein the container body is a syringe having a barrel, a plunger that is movably inserted into the barrel, and a plunger fixing device that positions and fixes the plunger that has moved toward the base end within the barrel, and wherein negative pressure is created within the barrel when the plunger moves toward the base end.

11. A sampling device for collecting a sampling liquid, a housing having a chamber and a needle hub connection; a sampling container that has a stopper that maintains a negative pressure inside the container body and that can be accommodated in the accommodation chamber; a plug penetration portion having an end portion capable of fluid-tightly penetrating the plug; a needle hub detachably connected to the needle hub connection portion; a puncture needle provided on the needle hub, puncturing a sample to deliver the sampling liquid from the sample to the sampling container via the stopper penetration portion; Equipped with A sampling device in which the end of the stopper-penetrating portion is movable within the housing from a non-penetrating position where it is spaced apart from the stopper of the sampling container and does not penetrate the stopper, to a penetrating position where it has penetrated the stopper.

Images