Cosmetic compositions, cosmetics

Abstract

The present invention aims to provide a cosmetic composition that contains (ascorbyl / tocopheryl) phosphoric acid and / or a salt thereof, while suppressing discoloration. [Solution] The cosmetic composition of the present invention comprises the following components (A), (B), (C), and (D), The mass ratio of component (B) to component (A) [component (B) / component (A)] is 2.0 or greater. The present invention is characterized in that the content of component (B) is 7.0% by mass or less. Component (A): Phospholipids Component (B): (Ascorbyl / Tocopheryl) Phosphate and / or its salt Ingredients (C): Polyhydric alcohol Ingredient (D): Water

Description

Technical Field

[0005]

[0001] The present invention relates to a composition for cosmetics and cosmetics.

Background Art

[0002] (Ascorbyl / tocopheryl) phosphate (EPC) and its salts have various functionalities such as antioxidant action, reactive oxygen species scavenging action, moisturizing action, and normalization of the production cycle of the stratum corneum, and are therefore added to various cosmetics (see, for example, Patent Document 1). Further, Patent Document 2 discloses a cosmetic containing a lipid membrane structure containing EPC and its salts.

Prior Art Documents

Patent Documents

[0003]

Patent Document 1

Patent Document 2

Summary of the Invention

Problems to be Solved by the Invention

[0004] However, EPC itself has a property of being easily oxidized, and there is a problem that when a large amount of EPC is blended, the cosmetic is likely to be colored due to the oxidation of EPC.

[0005] Therefore, an object of the present invention is to provide a composition for cosmetics that can suppress coloring while containing (ascorbyl / tocopheryl) phosphate and / or its salts.

Means for Solving the Problems

[0006] As a result of diligent research to achieve the above objective, the present inventors have found that a cosmetic composition containing a phospholipid, (ascorbyl / tocopheryl) phosphate and / or its salt, a polyhydric alcohol, and water, wherein the phospholipid and the (ascorbyl / tocopheryl) phosphate and / or its salt satisfy a specific mass ratio, and the (ascorbyl / tocopheryl) phosphate and / or its salt satisfy a specific content ratio, can suppress discoloration while containing (ascorbyl / tocopheryl) phosphate and / or its salt. The present invention was completed based on these findings.

[0007] In other words, the present invention provides a cosmetic composition comprising the following components (A), (B), (C), and (D), wherein the mass ratio of component (B) to component (A) [component (B) / component (A)] is 2.0 or more, and the content of component (B) is 7.0% by mass or less. Component (A): Phospholipids Component (B): (Ascorbyl / Tocopheryl) Phosphate and / or its salt Ingredients (C): Polyhydric alcohol Ingredient (D): Water

[0008] The above cosmetic composition preferably contains disc-shaped micelles. Including disc-shaped micelles makes it easier to stably incorporate (ascorbyl / tocopheryl) phosphoric acid and / or its salt into the cosmetic composition, and makes it easier to suppress discoloration of the cosmetic composition.

[0009] The above cosmetic composition preferably contains the following component (E). Ingredient (E): Polyoxyethylene phytostanol

[0010] Furthermore, the present invention provides a cosmetic composition comprising the above-mentioned cosmetic composition. [Effects of the Invention]

[0011] The cosmetic composition of the present invention can suppress discoloration while containing (ascorbyl / tocopheryl) phosphoric acid and / or a salt thereof. [Brief explanation of the drawing]

[0012] [Figure 1] This is a TEM image of the composition of Example 20. [Modes for carrying out the invention]

[0013] Unless otherwise specified in this specification, "X~Y" representing a numerical range means "X or more and Y or less". Also, unless otherwise specified in this specification, the mass % representing the content of an ingredient is the value with the total mass of the cosmetic composition set to 100% by mass.

[0014] [Composition for cosmetics] The cosmetic composition of the present invention comprises at least a phospholipid, (ascorbyl / tocopheryl) phosphoric acid and / or a salt thereof, a polyhydric alcohol, and water. In this specification, the above cosmetic composition may be referred to as "the cosmetic composition of the present invention."

[0015] In this specification, the above-mentioned "phospholipid" may be referred to as "component (A)", the above-mentioned "(ascorbyl / tocopheryl) phosphate and / or salt thereof" as "component (B)", the above-mentioned "polyhydric alcohol" as "component (C)", and the above-mentioned "water" as "component (D)".

[0016] Furthermore, the cosmetic composition of the present invention may also contain polyoxyethylene phytostanol. In this specification, the above-mentioned "polyoxyethylene phytostanol" may be referred to as "component (E)".

[0017] In other words, the cosmetic composition of the present invention comprises at least component (A), component (B), component (C), and component (D). The cosmetic composition of the present invention may further comprise component (E). Furthermore, the cosmetic composition of the present invention may comprise other components other than those listed above (A) to (E).

[0018] The cosmetic composition of the present invention preferably contains disk-shaped micelles (so-called bicelles). The above disk-shaped micelles have a disk-shaped lipid bilayer structure (so-called bicelle structure) containing at least component (A) and component (B) as constituent components. The above disk-shaped micelles may be present as dispersed single structures, or may form a structure (spherical or columnar structure) in which a plurality of disk-shaped micelles are stacked in a direction perpendicular to the disk plane. That is, in the cosmetic composition of the present invention, single disk-shaped micelles may be dispersed and present respectively, or a plurality of disk-shaped micelles may form a structure (spherical or columnar structure) stacked in a direction perpendicular to the disk plane.

[0019] The average particle size of the above disk-shaped micelles is not particularly limited, but is preferably 20 nm or more, more preferably 30 nm or more, and still more preferably 40 nm or more. When the average particle size is 20 nm or more, it becomes easier to secure a space for incorporating component (B) into the disk-shaped micelles. Further, the average particle size is preferably 100 nm or less, more preferably 90 nm or less, and still more preferably 80 nm or less. When the average particle size is 100 nm or less, it is possible to make the composition excellent in transparency while incorporating a sufficient amount of component (B). The measurement of the above average particle size can be carried out using a dynamic light scattering photometer or a transmission electron microscope (TEM).

[0020] By containing the above disk-shaped micelles, the cosmetic composition of the present invention can retain component (B) in the above disk-shaped micelles, particularly even when component (B) is contained. Thereby, it becomes easier to stably blend component (B) in the cosmetic composition, and it becomes easier to suppress the coloring of the cosmetic composition.

[0021] The pH of the cosmetic composition of the present invention is preferably 4.0 to 8.5, more preferably 5.0 to 7.5. When the pH of the cosmetic composition of the present invention is within the above range, the structure of the disk-shaped micelles can be further stabilized, and the stability as a composition can be improved.

[0022] <Component (A)> Component (A) is a phospholipid. Component (A) is, for example, a component that forms the above-mentioned disc-shaped micelles and is presumed to mainly constitute its planar part. Only one type of Component (A) may be used, or two or more types may be used.

[0023] Examples of Component (A) include complex lipids containing a phosphate residue, such as natural phospholipids, synthetic phospholipids, and hydrogenated phospholipids obtained by saturating the unsaturated carbon chains of natural-derived phospholipids with hydrogen. Examples of Component (A) include natural phospholipids such as phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, phosphatidylinositol, lysophosphatidylcholine, sphingomyelin, egg yolk lecithin, and soy lecithin; synthetic phospholipids such as dilauroyl phosphatidylcholine, dimyristoyl phosphatidylcholine, dipalmitoyl phosphatidylcholine, distearoyl phosphatidylcholine, dioleoyl phosphatidylcholine, and palmitoyl oleoyl phosphatidylcholine; and hydrogenated phospholipids such as hydrogenated soy lecithin, hydrogenated egg yolk lecithin, hydrogenated phosphatidylcholine, and hydrogenated phosphatidylserine. Among these, from the perspective of facilitating the formation of disc-shaped micelles, hydrogenated phospholipids are preferred, and hydrogenated lecithin is more preferred.

[0024] When Component (A) contains phosphatidylcholine, the content ratio of phosphatidylcholine is preferably 50% by mass or more, more preferably 70% by mass or more, based on 100% by mass of Component (A).

[0025] The content ratio of Component (A) is preferably 0.01 to 5.0% by mass, more preferably 0.03 to 3.0% by mass, based on 100% by mass of the cosmetic composition of the present invention. When the content ratio of Component (A) is 0.01% by mass or more, it becomes easier to form disc-shaped micelles. When the content ratio of Component (A) is 5.0% by mass or less, it becomes easier to exhibit the stability as a cosmetic composition.

[0026] <Ingredient (B)> Component (B) is (ascorbyl / tocopheryl)phosphate and / or a salt thereof. Component (B) is, for example, the main component that forms the disc-shaped micelle described above, and is presumed to mainly constitute its edge. Component (B) may be used alone or in combination of two or more types.

[0027] Examples of salts included in component (B) are alkali metal salts such as sodium salts and potassium salts; alkaline earth metal salts such as magnesium salts and calcium salts, with potassium salts being particularly preferred. An example of component (B) is (ascorbyl / tocopheryl) phosphate K [dl-α-tocopherol 2-L-ascorbic acid phosphate diester potassium salt].

[0028] The content of component (B) is 7.0% by mass or less, preferably 6.5% by mass or less, based on 100% by mass of the cosmetic composition of the present invention. By having a content of component (B) of 7.0% by mass or less, coloring of the cosmetic composition can be suppressed. Furthermore, the content of component (B) is not particularly limited, but is preferably 0.06% by mass or more, and more preferably 0.1% by mass or more, based on 100% by mass of the cosmetic composition of the present invention. By having a content of 0.06% by mass or more of component (B), it becomes easier to incorporate a sufficient amount of component (B) into the cosmetic composition.

[0029] In the cosmetic composition of the present invention, the mass ratio of component (B) to component (A) [component (B) / component (A)] is 2.0 or higher, preferably 2.5 or higher, and more preferably 3.0 or higher. A mass ratio of 2.0 or higher allows for the formation of disc-shaped micelles, resulting in excellent stability. Furthermore, while the mass ratio of component (B) to component (A) [component (B) / component (A)] is not particularly limited, it is preferably 12.0 or lower, more preferably 10.0 or lower, and even more preferably 8.0 or lower. A mass ratio of 12.0 or lower reduces the excess component (B), making it easier to prevent discoloration of the cosmetic composition. In particular, it further reduces the amount of free component (B) not contained in the disc-shaped micelles, making it easier to prevent discoloration of the cosmetic composition.

[0030] <Ingredient (C)> Component (C) is a polyhydric alcohol. Component (C) is added as a solvent for components (A) and (B) in the cosmetic composition of the present invention. Component (C) may be used alone or two or more types.

[0031] Examples of component (C) include glycols such as ethylene glycol, diethylene glycol, triethylene glycol, polyethylene glycol, propylene glycol, dipropylene glycol, polypropylene glycol, isoprene glycol, 1,3-butylene glycol, 1,2-butanediol, 1,3-propanediol, 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol, and 1,2-decanediol; glycerin compounds such as glycerin, diglycerin, and polyglycerin; and sugar alcohols such as xylitol, trehalose, maltitol, mannitol, sorbitol, erythritol, arabitol, ribitol, galactitol, glucitol, erythritol, glycosyltrehalose, and hydrolyzed hydrogenated starch. Among these, component (C) is particularly preferably 1,3-propanediol, dipropylene glycol, or 1,3-butylene glycol.

[0032] The content of component (C) is not particularly limited with respect to 100% by mass of the cosmetic composition of the present invention, but from the viewpoint of facilitating the stable formation of disc-shaped micelles, it is preferably 70.0% by mass or less, more preferably 50.0% by mass or less, and even more preferably 30.0% by mass or less. The content of component (B) is not particularly limited with respect to 100% by mass of the cosmetic composition of the present invention, but it is preferably 0.02% by mass or more, and more preferably 0.5% by mass or more.

[0033] In the cosmetic composition of the present invention, the mass ratio of component (C) to component (A) [component (C) / component (A)] is not particularly limited, but from the viewpoint of facilitating the stable formation of disc-shaped micelles, it is preferably 5.0 or higher, and more preferably 10.0 or higher. Furthermore, although the above mass ratio [component (C) / component (A)] is not particularly limited, it is preferably 7000 or lower, more preferably 3000 or lower, even more preferably 1000 or lower, and particularly preferably 500 or lower.

[0034] <Ingredient (D)> Component (D) is water. Component (D) is an ingredient added as a solvent to the cosmetic composition of the present invention. Examples of component (D) include purified water, tap water, hot spring water, deep sea water, etc. Furthermore, only one component (D) may be used, or two or more components may be used.

[0035] The content of component (D) is not particularly limited, but is preferably 20.0 to 95.0% by mass, and more preferably 40.0 to 90.0% by mass, based on 100% by mass of the cosmetic composition of the present invention.

[0036] <Ingredient (E)> Component (E) is polyoxyethylene phytostanol. By including component (E), the edges of the disc-shaped micelles can be reinforced, so that the cosmetic composition of the present invention can form disc-shaped micelles more stably. Component (E) may be used alone or two or more types may be used.

[0037] The average number of moles of ethylene oxide added to component (E) is preferably 10 to 40, and more preferably 20 to 35. Having the average number of moles of component (E) within this range facilitates the formation of disc-shaped micelles.

[0038] When the cosmetic composition of the present invention contains component (E), the mass ratio of component (E) to component (B) [component (E) / component (B)] is preferably greater than 0 and 1.5 or less, and more preferably 0.1 to 0.7. A mass ratio greater than 0 and 1.5 or less facilitates the more stable formation of disc-shaped micelles.

[0039] <Other ingredients> The cosmetic composition of the present invention may further contain other components in addition to the above components (A) to (E). The above other components are not particularly limited, but examples include surfactants other than components (A) and (E), lower alcohols, antibacterial agents, ultraviolet absorbers, powders, antioxidants, preservatives, fragrances, colorants, chelating agents, cooling agents, thickeners, vitamins, neutralizing agents, amino acids, pH adjusters, whitening agents, anti-inflammatory agents, deodorants, plant and animal extracts, metal ion sequestering agents, and other additives. Only one of the above other components may be used, or two or more may be used.

[0040] The cosmetic composition of the present invention can be produced by mixing the above-mentioned components and stirring them using a known method, such as a homomixer.

[0041] [Cosmetics] Cosmetics can be manufactured by mixing the cosmetic composition of the present invention with other components used in cosmetics. In other words, the cosmetic composition of the present invention can be used as a raw material (so-called intermediate raw material) for the manufacture of cosmetics. By using the cosmetic composition of the present invention, component (B) can be stably incorporated into cosmetics. Furthermore, the cosmetic composition of the present invention can also be used as a cosmetic itself.

[0042] In the present invention, a cosmetic composition containing the cosmetic composition of the present invention is obtained. In this specification, the "cosmetic composition containing the cosmetic composition of the present invention" may be referred to as the "cosmetic composition of the present invention." The content ratio of the cosmetic composition of the present invention to 100% by mass of the cosmetic composition of the present invention is not particularly limited, but is preferably 0.1 to 100% by mass, and more preferably 0.5 to 10.0% by mass.

[0043] Furthermore, the cosmetic composition of the present invention may further contain the other components listed above. That is, the other components may be added to the cosmetic composition of the present invention, or added to the cosmetic composition of the present invention (they may be added separately from the cosmetic composition of the present invention).

[0044] The dosage form of the cosmetic composition (or cosmetic) of the present invention is not particularly limited, but examples include various dosage forms such as lotion, cream, gel, emulsion, aerosol spray, natural spray, stick, powder, roll-on, and sheet (paper).

[0045] The cosmetic composition (or cosmetic) of the present invention is not particularly limited, but examples include skincare cosmetics such as moisturizing cosmetics, whitening cosmetics, acne care cosmetics, and anti-aging cosmetics (for example, aimed at wrinkle suppression, sagging suppression, etc.); scalp care cosmetics (for example, aimed at moisturizing, sebum suppression, etc.); deodorant cosmetics; sunscreen cosmetics; shaving cosmetics; body cleansers (for example, body shampoo, bar soap, etc.); and scalp cleansers. Furthermore, the cosmetic composition (or cosmetic) of the present invention may be, for example, a cosmetic, a quasi-drug, a pharmaceutical, or a general merchandise item.

[0046] The areas to which the cosmetic composition (or cosmetic) of the present invention is applied are not particularly limited, and include the face (e.g., forehead, around the eyes, corners of the eyes, cheeks, around the mouth, etc.), arms, elbows, back of the hands, fingertips, feet, knees, heels, neck, armpits, back, scalp, etc. [Examples]

[0047] The present invention will be described in more detail below based on examples, but the present invention is not limited to these examples. The amounts listed in the table are the amounts of each component (i.e., the amount of active ingredients in each raw material; so-called pure content), and are expressed in "mass%" unless otherwise specified.

[0048] Examples 1-11, Comparative Examples 1-5 Using the components shown in Table 1, cosmetic compositions for both the Examples and Comparative Examples were prepared by conventional methods and subjected to the evaluation tests described below. The evaluation results are also shown in Table 1.

[0049] The details of the ingredients listed in Tables 1-3 are as follows: <Ingredient (A)> Hydrogenated lecithin: Product name "PhosphoLipid PCSH70", manufactured by Nippon Seika Co., Ltd. <Ingredient (B)> (Ascorbyl / Tocopheryl) Phosphate K <Ingredient (C)> BG: 1,3-butylene glycol DPG: Dipropylene glycol Propanediol: 1,3-Propanediol <Ingredient (D)> Water: Purified water <Ingredient (E)> PEG-25 Phytostanol

[0050] (evaluation) The cosmetic compositions obtained in the examples and comparative examples were evaluated as follows. The evaluation results are shown in Table 1.

[0051] (1) Formation of disc-shaped micelles (bicelles) The cosmetic compositions of the examples and comparative examples were observed using a transmission electron microscope (TEM) and evaluated according to the following criteria. <Evaluation Criteria> ○ (Good): Disc-shaped micelles (bycells) were observed. × (Defective): Disc-shaped micelles (bycells) could not be identified.

[0052] (2) Suppression of discoloration The cosmetic compositions of the examples and comparative examples were stored for 14 days at 25°C and 40°C, respectively, after preparation. The appearance of the cosmetic compositions after storage was visually observed and evaluated according to the following criteria. <Evaluation Criteria> ○ (Good): The composition showed no or only slight discoloration after being stored at either 25°C or 40°C compared to before storage. × (Defective): The composition was noticeably discolored after being stored under either 25°C or 40°C compared to before storage.

[0053] [Table 1]

[0054] Furthermore, the pH of the cosmetic composition in Example 4 was 6.6, the pH of the cosmetic composition in Example 5 was 6.5, the pH of the cosmetic composition in Example 6 was 6.4, the pH of the cosmetic composition in Example 9 was 6.5, the pH of the cosmetic composition in Example 10 was 6.3, and the pH of the cosmetic composition in Example 11 was 6.5.

[0055] Disc-shaped micelles were observed in the cosmetic compositions of Examples 1 to 11. Furthermore, discoloration of the cosmetic compositions was suppressed. On the other hand, when component (A) was present in a large amount relative to component (B), disc-shaped micelles were not formed (Comparative Examples 1 to 3). Also, when the content of component (B) exceeded 7% by mass, disc-shaped micelles were formed, but discoloration of the cosmetic compositions could not be suppressed (Comparative Examples 4 and 5).

[0056] Examples 12, 13 Cosmetic compositions were prepared in the same manner as in Examples 1 to 11, except that the ingredients used were changed as follows. Note that the amount of phytopresome is expressed as the amount of the raw material itself. (Example 12) phytopresome (product name, manufactured by Nippon Seika Co., Ltd.): Ingredient (A) 0.5% by mass (Ascorbyl / Tocopheryl) Phosphate K: Component (B) 4.0% by mass BG: Component (C) 20.0% by mass Water: component (D) remainder Total 100% by mass (Example 13) phytopresome (product name, manufactured by Nippon Seika Co., Ltd.): Ingredient (A) 0.5% by mass (Ascorbyl / Tocopheryl) Phosphate K: Component (B) 4.0% by mass BG: Component (C) 20.0% by mass PEG-25 Phytostanol: Ingredient (E) 2.0% by mass Water: component (D) remainder Total 100% by mass When the obtained cosmetic composition was evaluated using the same criteria as described above, disc-shaped micelles were observed, indicating that the coloring of the cosmetic composition was suppressed.

[0057] Examples 14-19 Cosmetic compositions were prepared using the components shown in Table 2 by conventional methods, and the evaluation results are also listed in Table 2. The "formation of disc-shaped micelles (bycells)" and "inhibition of coloring" were evaluated using the same methods as in the above examples.

[0058] [Table 2]

[0059] Furthermore, the pH of the cosmetic composition in Example 16 was 6.9, and the pH of the cosmetic composition in Example 18 was 6.0.

[0060] As shown in Table 2, disc-shaped micelles were also observed in the cosmetic compositions of Examples 14 to 19, and the discoloration of the cosmetic compositions was suppressed.

[0061] Examples 20-26 Cosmetic compositions were prepared using the components shown in Table 3 by conventional methods, and the evaluation results are also shown in Table 3. The cosmetic compositions of Examples 24-26 were prepared by adding purified water, BG, and other components to the composition of Example 9, which had been prepared once. "Disc-shaped micelle (bycell) formation" and "coloration suppression" were evaluated using the same methods as in the above examples.

[0062] [Table 3]

[0063] Furthermore, the pH of the cosmetic composition in Example 22 was 6.0, the pH of the cosmetic composition in Example 23 was 5.0, the pH of the cosmetic composition in Example 24 was 7.0, the pH of the cosmetic composition in Example 25 was 7.0, and the pH of the cosmetic composition in Example 26 was 7.5.

[0064] Furthermore, the cosmetic composition of Example 20 was observed using a transmission electron microscope (TEM). Specifically, Figure 1 shows the TEM image of Example 20. The structure of disc-shaped micelles (bicelles) was confirmed in Example 20, and it was inferred that disc-shaped micelles (bicelles) were formed in the cosmetic composition of the example.

[0065] The following are examples of cosmetic formulations (lotions) using the cosmetic composition of the present invention (total amount is 100% by mass). [Table 4]

[0066] The following are examples of cosmetic formulations (creams) using the cosmetic composition of the present invention (total amount is 100% by mass). [Table 5]

[0067] Variations of the present invention are described below. [Note 1] It contains the following ingredients (A), (B), (C), and (D): The mass ratio of component (B) to component (A) [component (B) / component (A)] is 2.0 or greater. A cosmetic composition in which the content of component (B) is 7.0% by mass or less. Component (A): Phospholipids Component (B): (Ascorbyl / Tocopheryl) Phosphate and / or its salt Ingredients (C): Polyhydric alcohol Ingredient (D): Water [Note 2] The cosmetic composition described in Appendix 1, comprising disc-shaped micelles. [Note 3] A cosmetic composition as described in Appendix 1 or 2, comprising the following ingredient (E). Ingredient (E): Polyoxyethylene phytostanol [Note 4] A cosmetic containing the cosmetic composition described in any one of the notes 1 to 3.

Claims

1. It contains the following ingredients (A), (B), (C), and (D): The mass ratio of component (B) to component (A) [component (B) / component (A)] is 2.0 or greater. A cosmetic composition in which the content of component (B) is 7.0% by mass or less. Component (A): Phospholipids Component (B): (Ascorbyl / Tocopheryl) Phosphate and / or Salt thereof Ingredient (C): Polyhydric alcohol Component (D): water

2. The cosmetic composition according to claim 1, comprising disc-shaped micelles.

3. A cosmetic composition according to claim 1 or 2, comprising the following component (E). Ingredient (E): Polyoxyethylene phytostanol

4. A cosmetic composition comprising the cosmetic composition described in claim 1 or 2.

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