Detection of homologous recombination repair defects

Abstract

Providing detection of homologous recombination repair defects. [Solution] Methods for generating homologous recombination deficit (HRD) scores, methods for determining a reference HRD score, methods for determining the HRD status of a test subject having one or more cancer types, and / or methods for treating a disease based on the HRD status are provided herein. Additional methods, as well as related systems, apparatus, and computer-readable media, are also provided. This disclosure provides methods for generating homologous recombination deficit (HRD) scores and methods for determining the HRD status of a test subject having a condition (e.g., cancer).

Claims

[Claim 1] The invention described in the specification.

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