Disinfectant cleaning agent composition

Abstract

Provided is a germicidal and cleaning agent composition that is excellent in achieving both germicidal property and cleaning property when used at a low concentration. 【Solution means】A germicidal and cleaning agent composition containing the following component (a), component (b), and water, wherein the molar ratio (a) / (b) of component (a) to component (b) is 0.05 or more and less than 1, and the concentration of component (a) in the germicidal and cleaning agent composition when diluted with water for use is 1 ppm or more and 100 ppm or less. Component (a): A compound represented by the following general formula (a1) JPEG2026111262000007.jpg2570 (In the general formula (a1), R 1a and R 2a are each independently a linear or branched alkyl group having 8 carbon atoms, and R 3a and R 4a are each independently a linear or branched alkyl group having 1 to 3 carbon atoms, and X - is an anion.) Component (b): An anionic surfactant having one or more selected from a sulfonic acid group, a sulfate ester group, and salts of these substituents

Description

[Technical Field]

[0001] This invention relates to a disinfectant and cleaning agent composition. [Background technology]

[0002] Conventionally, compositions containing cationic surfactants and anionic surfactants have been used as disinfectant detergents, and various studies have been conducted on them.

[0003] For example, Patent Document 1 discloses a disinfectant cleaning composition comprising an anionic surfactant and a cationic surfactant, wherein the anionic surfactant is at least one selected from the group consisting of carboxylic acid-type anionic surfactants, sulfonic acid-type anionic surfactants and sulfate ester-type anionic surfactants, and the cationic surfactant is at least one selected from the group consisting of alkyldimethylhydroxyethylammonium salts, dialkyldimethylammonium salts (alkyl chain length of 8 or less carbon atoms) and trialkyl-type quaternary ammonium salts, and the disinfectant cleaning composition is characterized in that it is used for cleaning dishes, kitchens, stores, glass, bathrooms, or toilets.

[0004] Furthermore, Patent Document 2 contains, (a) 10 to 50% by mass of nonionic surfactant, (b) Anionic surfactant in an amount of 0.25 to 5% by mass, (c) One or more selected from polyhexamethylene biguanide, polyhexamethylene biguanide salts, polylysine, and polylysine salts in an amount of 0.01 to 2% by mass (however, the amount of polyhexamethylene biguanide salt or polylysine salt is the amount in terms of polyhexamethylene biguanide or polylysine, respectively), (d) Cationic surfactants, and, (e) Contains an amphoteric surfactant, The molar ratio (b) / (d) of the content of (b) to the content of (d) is between 0.1 and 1.0. The molar ratio (d) / (e) of the content of (d) to the content of (e) is 0.20 to 5, A liquid detergent composition is disclosed.

Prior Art Documents

Patent Documents

[0005]

Patent Document 1

Patent Document 2

Summary of the Invention

Problems to be Solved by the Invention

[0006] y According to the antibacterial detergent composition disclosed in Patent Document 1, it is said that the antibacterial power and detergency are high and no insoluble matters such as precipitation occur. According to the liquid detergent composition disclosed in Patent Document 2, it is said that it has detergency and antibacterial properties in cleaning with a high load of dirt such as oil stain. However, there was room for improvement from the viewpoint of achieving both bactericidal property and detergency when used at a dilute concentration.

[0007] Therefore, an object of the present invention is to provide a bactericidal detergent composition that is excellent in achieving both bactericidal property and detergency when used at a dilute concentration.

Means for Solving the Problems

[0008] The present inventors have found that by containing a specific cationic surfactant and a specific anionic surfactant in a specific molar ratio and having the concentration of the specific cationic surfactant in the bactericidal detergent composition within a specific range when diluted with water and used, the above problems can be solved. That is, the present invention provides the following [1]. 〔1〕A germicidal detergent composition containing the following component (a), component (b), and water, wherein the molar ratio (a) / (b) of component (a) to component (b) is 0.05 or more and less than 1, and the concentration of component (a) in the germicidal detergent composition when diluted with water and used is 1 ppm or more and 100 ppm or less. Component (a): A compound represented by the following general formula (a1) [Chemical formula] (In the general formula (a1), R 1a and R 2a are each independently a linear or branched alkyl group having 8 carbon atoms, and R 3a and R 4a are each independently a linear or branched alkyl group having 1 to 3 carbon atoms, and X - is an anion.) Component (b): An anionic surfactant having one or more selected from a sulfonic acid group, a sulfate ester group, and salts of these substituents [Advantages of the Invention]

[0009] According to the present invention, there is provided a germicidal detergent composition excellent in achieving both bactericidal property and detergency when used at a dilute concentration. Here, the "dilute concentration" refers to a concentration of component (a) in the germicidal detergent composition of 1 ppm or more and 100 ppm or less when the germicidal detergent composition of the present invention is diluted with water and used. [Modes for Carrying Out the Invention]

[0010] [Germicidal Detergent Composition] The germicidal detergent composition of the present invention (hereinafter also simply referred to as "composition") is a germicidal detergent composition containing the following component (a), component (b), and water, wherein the molar ratio (a) / (b) of component (a) to component (b) is 0.05 or more and less than 1, and the concentration of component (a) in the germicidal detergent composition when diluted with water and used is 1 ppm or more and 100 ppm or less. Component (a): A compound represented by the following general formula (a1)

[0011] [Chemical formula]

[0012] (In the general formula (a1), R 1a and R 2a are each independently a linear or branched alkyl group having 8 carbon atoms, and R 3a and R 4a are each independently a linear or branched alkyl group having 1 to 3 carbon atoms, and X - is an anion.) (Component (b): An anionic surfactant having one or more selected from a sulfonic acid group, a sulfate ester group, and salts of these substituents

[0013] According to the present invention, there is an effect that it is excellent in achieving both bactericidal properties and detergency when used at a dilute concentration. The reason for this is not necessarily clear, but it is considered as follows. The hydrophilic group of the cationic surfactant is positively charged, and the hydrophilic group of the anionic surfactant is negatively charged. Therefore, usually, when a cationic surfactant and an anionic surfactant coexist in an aqueous composition, an ion complex is formed, and insoluble substances such as precipitates are generated, and the functions of each surfactant, particularly the bactericidal performance of the cationic surfactant in the dilute concentration region, are not exhibited. However, in the present invention, by using a specific cationic surfactant (component (a)) and a specific anionic surfactant (component (b)) in an aqueous composition, it is considered that the ion complex formed between component (a) and component (b) can exist in a state of a weak interaction that does not become insoluble. Moreover, by setting the alkyl group of component (a) to a specific number of carbon atoms, it is considered possible to increase the hydrophobicity of the ion complex formed between component (a) and component (b) while maintaining water solubility. As a result, it is presumed that the ion complex of component (a) and component (b) is suitably adsorbed onto the surface of the bacterial cell membrane, and that the bactericidal performance of component (a) is exerted by promoting the weakening of the bacterial cell membrane in contact with component (a). On the other hand, it is presumed that by adjusting the molar ratio of component (a) to component (b) (a) / (b) to a specific range (0.05 or more and less than 1), a cleaning function of component (b) is also exerted by component (b) as there is an excess amount of component (b) in the aqueous composition that is not used for the formation of the ion complex compared to component (a).

[0014] <(a) Components> The composition of the present invention contains, as component (a), a compound represented by the following general formula (a1). The compound represented by the following general formula (a1) is a cationic surfactant. The composition can exhibit bactericidal properties by containing component (a).

[0015] [ka]

[0016] (In general formula (a1), R 1a and R 2a Each of these is independently a linear or branched alkyl group having 8 carbon atoms, and R 3a and R 4a Each of these is independently a linear or branched alkyl group having 1 to 3 carbon atoms, and X - It is an anion.

[0017] (a1) In the compound of general formula (a1) which is component R 1a and R 2a Each of these is independently a linear or branched alkyl group having 8 carbon atoms, preferably a linear alkyl group. From the viewpoint of achieving both bactericidal and cleaning properties when used at dilute concentrations, R 1a and R 2a It is preferable that they are identical to each other. R 3a and R 4aEach of these is independently a linear or branched alkyl group having 1 to 3 carbon atoms. Examples of alkyl groups having 1 to 3 carbon atoms include groups selected from methyl, ethyl, and propyl groups. X - It is an anion. From the viewpoint of availability, halogen ions or alkyl sulfate ions having 1 to 3 carbon atoms are preferred as anions. Examples of halogen ions include chlorine ions, bromo ions, and iodide ions, with chlorine ions being preferred from the viewpoint of availability. Examples of alkyl sulfate ions having 1 to 3 carbon atoms include methyl sulfate ions, ethyl sulfate ions, and propyl sulfate ions, with ethyl sulfate ions being preferred from the viewpoint of availability.

[0018] (a) The components may be used individually or in combination or containing two or more components. There are no limitations on the mixing ratio (mass ratio) when using two or more components.

[0019] As described above, component (a) is a compound represented by the general formula (a1) above, and the molecular weight (Mw) of component (a) is usually 250 or more, preferably 300 or more, and preferably 600 or less, more preferably 500 or less, and even more preferably 450 or less.

[0020] The disinfectant cleaning agent composition of the present invention is a composition comprising a cationic surfactant of component (a). The amount of cationic surfactant is the amount added in terms of effective content at the time of preparation of the composition, and this corresponds to the content in the composition. The content of component (a) in the composition of the present invention is preferably 0.01% by mass or more, more preferably 0.1% by mass or more, even more preferably 0.2% by mass or more, and even more preferably 0.3% by mass or more, from the viewpoint of achieving both bactericidal and cleaning properties when used at a dilute concentration, and from the viewpoint of economic efficiency, it is preferably 15% by mass or less, more preferably 10% by mass or less, even more preferably 8% by mass or less, even more preferably 5% by mass or less, and even more preferably 3.5% by mass or less. Furthermore, only when determining the content of component (a) in the composition by analysis, the content of component (a) is determined by the anion of component (a) (the counterion (X) of the quaternary ammonium ion represented by general formula (a1)). - Even if the other component is not a chlorion, it can be calculated by converting it to a chlorine salt.

[0021] <(b) Component> The composition of the present invention contains, as component (b), an anionic surfactant having one or more selected from a sulfonic acid group (-SO3H), a sulfate ester group (-O-SO3H), and salts of these substituents. The composition can exhibit cleaning performance by containing component (b). (b) The anionic surfactant of component (b) preferably has a linear or branched alkyl group, from the viewpoint of achieving both bactericidal and cleaning properties when used at dilute concentrations, and the number of carbon atoms of the alkyl group is preferably 6 or more, more preferably 8 or more, even more preferably 10 or more, and from the viewpoint of storage stability, it is preferably 20 or less, more preferably 18 or less, even more preferably 16 or less, and even more preferably 14 or less. Note that, in this context, "(b) the number of carbon atoms in the alkyl group of component (b)" refers to the number of carbon atoms constituting each alkyl group, not the total number of carbon atoms, if component (b) has multiple alkyl groups.

[0022] (b) The anionic surfactant of component (b) is preferably one or more selected from alkyl sulfonates, alkyl sulfates, (di)alkyl sulfosuccinates, alkylbenzene sulfonates, internal olefin sulfonates, α-olefin sulfonates, α-sulfo fatty acid esters, and alkyl ether sulfates, having a linear or branched alkyl group having 6 to 20 carbon atoms. (b) The anionic surfactant of component (b) is more preferably one or more selected from alkyl sulfonates, alkyl sulfates, (di)alkyl sulfosuccinates, and alkylbenzene sulfonates, having a linear or branched alkyl group having 6 to 20 carbon atoms.

[0023] As described above, component (b) has one or more selected from a sulfonic acid group, a sulfate ester group, and salts of their substituents, and its counterion is preferably one or more selected from a hydrogen ion, an alkali metal ion, an alkaline earth metal ion, an ammonium ion, and an organic ammonium ion. Examples of alkali metal ions include sodium ions or potassium ions, examples of alkaline earth metal ions include calcium ions or magnesium ions, and examples of organic ammonium ions include alkanolamines having 1 to 3 alkanol groups with 2 or 3 carbon atoms, preferably one or more selected from sodium ions, potassium ions, and alkanolamines. (b) The molecular weight (Mw) of component is preferably 150 or more, more preferably 200 or more, even more preferably 230 or more, and even more preferably 250 or more, and also preferably 800 or less, more preferably 700 or less, even more preferably 600 or less, and even more preferably 550 or less.

[0024] The disinfectant cleaning agent composition of the present invention is a composition comprising an anionic surfactant of component (b). The amount of anionic surfactant is the amount added in terms of effective content at the time of preparation of the composition, and this corresponds to the content in the composition. (b) The content of component (b) in the composition is preferably 0.5% by mass or more, more preferably 0.8% by mass or more, even more preferably 1% by mass or more, even more preferably 1.5% by mass or more, even more preferably 2.0% by mass or more, and also preferably 30% by mass or less, more preferably 25% by mass or less, even more preferably 20% by mass or less, even more preferably 15% by mass or less, and even more preferably 10% by mass or less. Furthermore, only when determining the content of component (b) in the composition by analysis, the content of component (b) may be determined by converting it to a sodium salt, even if the counterions of the sulfonic acid group and sulfate ester group of component (b) are other than sodium ions.

[0025] In the composition of the present invention, the molar ratio (a) / (b) of component (a) to component (b) is 0.05 or more, preferably 0.06 or more, more preferably 0.07 or more, even more preferably 0.08 or more, and also less than 1, preferably 0.95 or less, more preferably 0.9 or less, even more preferably 0.85 or less, even more preferably 0.5 or less, even more preferably 0.4 or less, and even more preferably 0.2 or less. Furthermore, when determining the molar amount of component (a) in the composition by analysis, it can be uniquely determined from the relationship between the structure and content of the quaternary ammonium ion (the part other than the counterion) represented by the general formula (a1) of component (a). Furthermore, when determining the molar amount of component (b) in the composition by analysis, it can be uniquely determined from the relationship between the structure and content of the anionic portion (the portion other than the counterion) of component (b).

[0026] As described above, in the range where the molar ratio (a) / (b) of component (a) to component (b) is 0.05 or more and less than 1, the mass ratio (a) / (b) of component (a) to component (b) in the composition of the present invention is preferably 0.001 or more, more preferably 0.005 or more, even more preferably 0.01 or more, and even more preferably 0.05 or more, and also preferably 8.0 or less, more preferably 6.0 or less, even more preferably 4.0 or less, and even more preferably 2.0 or less.

[0027] <Water> The composition of the present invention contains water. The water content in the composition of the present invention may be the remainder of component (a) and component (b), or the remainder of component (a), component (b), and component (c). In other words, the disinfectant cleaning agent composition of the present invention is a composition comprising water. The amount of water added is the amount added at the time of preparation of the composition, and this corresponds to the content in the composition. The water content in the composition of the present invention is preferably 50% by mass or more, more preferably 60% by mass or more, even more preferably 70% by mass or more, and also preferably 99.8% by mass or less, more preferably 99.5% by mass or less, even more preferably 99% by mass or less, even more preferably 98% by mass or less, and even more preferably 95% by mass or less, from the viewpoint of dissolving components (a) and (b). Furthermore, a composition obtained by diluting the present invention with water also falls under the category of the present invention.

[0028] <(c) component> From the viewpoint of improving bactericidal properties, the composition of the present invention preferably further contains the following component (c). (c) Components: Organic amines Examples of organic amines include alkylamines, alkanolamines, aminoalkanediols, alkoxyamines, and heterocyclic amines, and one or more of these can be used. Among these, one or more selected from alkanolamines and alkylamines are preferred, with alkanolamines being more preferred.

[0029] Examples of alkylamines include ethylamine, diethylamine, triethylamine, n-propylamine, di-n-propylamine, isopropylamine, diisopropylamine, n-butylamine, tert-butylamine, sec-butylamine, n-pentylamine, n-hexylamine, N,N-dimethylethylamine, N,N-diethylmethylamine, and N,N-dimethylbutylamine.

[0030] Examples of alkanolamines include monoethanolamine, diethanolamine, triethanolamine, n-propanolamine, isopropanolamine, 2-amino-2-methyl-1-propanol, N-methylethanolamine, N-ethylethanolamine, Nn-butylethanolamine, N-methyldiethanolamine, N-ethyldiethanolamine, N,N-dimethylethanolamine, N,N-diethylethanolamine, N,N-dimethylpropanolamine, N,N-dimethylisopropanolamine, 2-(dimethylamino)-2-methyl-1-propanol, N-(2-aminoethyl)ethanolamine, and 2-(2-aminoethoxy)ethanol. Among these, one or more selected from monoethanolamine, diethanolamine, triethanolamine, and 2-amino-2-methyl-1-propanol are preferred, one or more selected from monoethanolamine and 2-amino-2-methyl-1-propanol are more preferred, and monoethanolamine is even more preferred.

[0031] Examples of aminoalkanediols include 2-amino-1,3-propanediol, 2-amino-2-ethyl-1,3-propanediol, 3-(methylamino)-1,2-propanediol, and 3-(dimethylamino)-1,2-propanediol. Examples of alkoxyamines include 3-methoxypropylamine and 3-ethoxypropylamine. Examples of heterocyclic amines include pyrrolidine, piperidine, piperazine, 1-(2-hydroxyethyl)piperazine, and morpholine.

[0032] (c) The molecular weight (Mw) of component is preferably 30 or more, more preferably 40 or more, even more preferably 50 or more, and even more preferably 55 or more, and also preferably 300 or less, more preferably 200 or less, even more preferably 150 or less, and even more preferably 100 or less.

[0033] The disinfectant and cleaning agent composition of the present invention is preferably a composition comprising an organic amine of component (c). The amount of organic amine is the amount added in terms of effective content at the time of preparation of the composition, and this corresponds to the content in the composition. If the composition of the present invention contains component (c), the content of component (c) in the composition is preferably 0.5% by mass or more, more preferably 1% by mass or more, even more preferably 1.5% by mass or more, and even more preferably 2% by mass or more, from the viewpoint of improving bactericidal activity, and from the viewpoint of odor, preferably 20% by mass or less, more preferably 15% by mass or less, even more preferably 10% by mass or less, and even more preferably 8% by mass or less.

[0034] In the composition of the present invention, the molar ratio of the total of components (a) and (c) to component (b) [(a)+(c)] / (b) is preferably 0.5 or more, more preferably 1 or more, even more preferably 1.5 or more, even more preferably 1.8 or more, even more preferably 2.4 or more, even more preferably 3 or more, even more preferably 3.8 or more, and also preferably 50 or less, more preferably 20 or less, even more preferably 10 or less, even more preferably 8 or less, even more preferably 7.5 or less, even more preferably 6 or less, even more preferably 5 or less, and even more preferably 4.5 or less.

[0035] In the composition of the present invention, the mass ratio of the total of components (a) and (c) to component (b) [(a)+(c)] / (b) is preferably 0.05 or higher, more preferably 0.1 or higher, even more preferably 0.15 or higher, even more preferably 0.3 or higher, even more preferably 0.4 or higher, even more preferably 0.5 or higher, even more preferably 0.7 or higher, even more preferably 0.9 or higher, and also preferably 8 or lower, more preferably 5 or lower, even more preferably 3 or lower, even more preferably 2 or lower, and even more preferably 1.5 or lower.

[0036] <Other ingredients> In addition, the compositions of the present invention may contain, as optional components, cationic surfactants other than component (a), anionic surfactants other than component (b), nonionic surfactants, dispersants, thickeners, pH adjusters, texture enhancers, colorants, antioxidants, chelating agents, viscosity modifiers, defoamers, stabilizers (including hydrotropes), enzymes, fragrances, and the like.

[0037] As nonionic surfactants, preferred nonionic surfactants are selected from alkylglyceryl ethers having an alkyl group with 8 to 12 carbon atoms, preferably 8 to 10 carbon atoms, and polyoxyalkylene alkyl ethers having an alkyl group with 8 to 14 carbon atoms, preferably 8 to 12 carbon atoms, and an oxyalkylene group with an average addition mole number of 3 to 20, preferably 3 to 10, more preferably 3 to 6 carbon atoms, and even more preferably the oxyalkylene group is an oxyethylene group.

[0038] As a dispersant, a polymer containing acrylic acid as a monomer unit can be used. For example, a polymer containing 30 mol% or more, preferably 50 mol% or more, of acrylic acid in its total constituent monomers may be used. Specific examples of dispersants include polyacrylic acid or its salts, and acrylic acid-maleic acid copolymers. The weight-average molecular weight of the dispersant is, for example, 1,000 or more, preferably 2,000 or more, and 70,000 or less, preferably 50,000 or less. The weight-average molecular weight is measured by gel permeation chromatography (GPC) using polyethylene glycol of known molecular weight as a standard substance.

[0039] Examples of thickening agents include water-soluble polymer thickeners and thickeners selected from hydrogenated castor oil. Examples of water-soluble polymer thickeners include polysaccharides, cellulose derivatives, and synthetic water-soluble polymers. As water-soluble polymer thickeners, polysaccharides and cellulose derivatives are preferred, with polysaccharides being more preferred. Examples of thickening polysaccharides include karaya gum, tragacanth gum, gum arabic, acemannan, konjac mannan, acacia gum, gutti gum, guar gum, locust bean gum, carrageenan, xanthan gum, gellan gum, pullulan, dextran, casein, gelatin, keratin, glutelin, glucagon, gluten, zein, and shellac. Among these, thickening polysaccharides selected from carrageenan, xanthan gum, guar gum, and gellan gum are preferred, and thickening polysaccharides selected from xanthan gum and guar gum are more preferred.

[0040] Examples of chelating agents include hydroxypolycarboxylic acids or their salts such as citric acid, malic acid, tartaric acid, and succinic acid; methylglycine diacetic acid, glutamic acid diacetic acid, hydroxyethyliminodiacetic acid, ethylenediamine disuccinic acid, nitrilotriacetic acid, 1,3-propanediamine triacetic acid, 1,3-diamino-2-hydroxypropanetetraacetic acid, glycol etherdiaminetetraacetic acid, ethylenediaminetetraacetic acid, diethylenetriaminepentaacetic acid, triethylenetetraaminehexaacetic acid, dihydroxyethylglycine, hydroxyethylethylenediaminedicarboxymethylglutamic acid or their salts; condensed phosphoric acid such as tripolyphosphate or its salts; and the like. These chelating agents may be used individually or in combination of two or more. Preferred chelating agents include citric acid, malic acid, methylglycine diacetic acid, glutamate diacetic acid, ethylenediaminetetraacetic acid, tripolyphosphate, and salts thereof, with aminopolycarboxylic acids such as methylglycine diacetic acid, glutamate diacetic acid, and ethylenediaminetetraacetic acid, or their salts, being more preferred.

[0041] As an antifoaming agent, one that exhibits excellent foam suppression at dilute concentrations during use is preferred. Specific compounds that are preferred include one or more selected from polyalkylene glycols with C3 or C4 alkylene oxide as monomer units, and silicone compounds. These can also be used in combination. Examples of polyalkylene glycols with C3 or C4 alkylene oxide as monomer units include polypropylene glycol and polybutylene glycol, with polypropylene glycol being preferred. The number-average molecular weight of polyalkylene glycols, which use alkylene oxides having 3 or 4 carbon atoms as monomer units, is preferably 1,000 or more, more preferably 1,500 or more, even more preferably 2,000 or more, and preferably 20,000 or less, more preferably 10,000 or less, even more preferably 6,000 or less, and even more preferably 4,000 or less, from the viewpoint of suppressing foaming during use. The number-average molecular weight can be determined from the hydroxyl value. The hydroxyl value can be measured according to the method specified in JIS K-1557-1. The silicone compound is not particularly limited and can be in oil, solution, powder, or emulsion form. Examples include polyorganosiloxane oil such as polydimethylsiloxane, dispersions of polyorganosiloxane resins, polyorganosiloxane emulsions, and combinations of polyorganosiloxane and silica particles in which polyorganosiloxane is chemically adsorbed or melted onto silica. One example is polydimethylsiloxane.

[0042] Examples of stabilizers include one or more selected from alcohols having 2 to 12 carbon atoms, preferably 3 to 10 carbon atoms; glycol-based solvents having 2 to 14 carbon atoms; and glycol ether-based solvents in which a hydrocarbon group having 2 to 6 carbon atoms is bonded to an alkylene glycol group having 2 to 3 carbon atoms. Preferably, the hydrotrope is an alkylbenzene sulfonate having 1 to 3 alkyl groups with 1 to 3 carbon atoms. Specifically, this includes p-toluenesulfonic acid, xylenesulfonic acid, cumenesulfonic acid, and their salts, with p-toluenesulfonic acid, cumenesulfonic acid, and their salts being more preferred. The salts are preferably sodium salts, potassium salts, or magnesium salts.

[0043] Examples of enzymes include proteases, amylases, and lipases, with one or more selected from proteases, amylases, and lipases being preferred. Preferred lipases include triacylglycerol lipase (EC3.1.1.3), cholesterol esterase (EC3.1.1.13), monoacylglycerol lipase (EC3.1.23), and lipoprotein lipase (EC3.1.1.34). The origin of the lipase is not limited, but may be animal-derived, plant-derived, or microbial-derived. Examples of microbial-derived lipases include those from the genera Rhizopus, Aspergillus, Mucor, Pseudomonas, Geotrichum, Penicillium, and Candida. For lipase, the following can be used: Lipase A "Amano" 6, Lipase AY "Amano" 30SD, Lipase GS "Amano" 250G, Lipase R "Amano", Lipase DF "Amano" 15, Lipase MER "Amano" (all manufactured by Amano Enzyme Co., Ltd.), Olipase (Nagase & Co., Ltd.), Lipase MY, Lipase OF, Lipase PL, Lipase PLC, Lipase QLM, Lipase QLC, Phospholipase D (all manufactured by Meito Sangyo Co., Ltd.), Lipoprotein Lipase (Oriental Yeast Co., Ltd.), Lipase (Toyo Jozo Co., Ltd.), Lipex, Lipolase, Lipase SP-225 (all manufactured by Novo Carnegie Co., Ltd.), Lipase (Gist Co., Ltd.), Lipase A, Lipase B (all manufactured by Sapporo Breweries Ltd.). Examples of amylases include bacteria such as Bacillus subtilis Marburg, Bacillus subtilis natto, Bacillus amyloliquefaciens, Bacillus licheniformis, Bacillus scereus, Bacillus macerans, Pseudomonas stutzeri, and Klebusiella aerogenes; actinomycetes such as Streptomyces griseus; and Aspergillus oryzae and Aspergillus niger. Many types of amylase can be used, including those obtained from various organisms such as fungi (e.g., niger), seeds of grasses and legumes, and digestive glands of animals such as humans and pigs. The amylase used in this invention can be obtained by inoculating host cells transformed with the aforementioned microorganisms or their mutant strains, or with recombinant vectors having DNA sequences encoding these enzymes or their mutants, into a culture medium containing an assimilated carbon source, nitrogen source, and other essential nutrients, culturing them according to conventional methods, and following general enzyme collection and purification methods. The enzyme solution obtained in this way can be used as is, but it can also be further purified, crystallized, powdered, or liquid-formulated by known methods. The amylase used in this invention is preferably α-amylase. Examples of commercially available amylases that can be used include the trademarked Rapidase (manufactured by Gistbrokers), the trademarked Termamyl, Duramyl, and Steinzyme (manufactured by Novozymes Japan Co., Ltd.), Amplify (manufactured by Novozymes), and the trademarked Plaster ST and Plaster OxAm (manufactured by Genencor International). Examples of proteases include those that can act in neutral or alkaline aqueous solutions. Specific examples of preferred proteases include alkaline proteases described in International Publication No. 99 / 018218, preferably those in which 70% or more of the amino acid sequence shown in SEQ ID NO: 1 or 2 is preserved, and alkaline proteases described in Japanese Patent Publication No. 5-25492, preferably alkaline protease K-16 or alkaline protease K-14. Other examples include proteases produced by Bacillus subtilisins sold under the trade names Sabinase®, Cannase®, Evalase®, Alcalase®, Polarzyme®, and Esperase® by Novozymes, and proteases supplied under the trade names FN2®, FN3®, and FN4®, Plafect®, and Plafect Prime® by DuPont, or their variants. Among these, enzymes in which more than 80% of the amino acid sequence shown in Sequence ID No. 1 or 2 described in International Publication No. 99 / 018218 is conserved, such as sabinase, evalase, alcalase, and Progress (manufactured by Novozymes), and Plafect and Plafect Prime (manufactured by DuPont).

[0044] The disinfectant and cleaning agent composition of the present invention is a composition comprising, as described above, a cationic surfactant other than component (a), an anionic surfactant other than component (b), a nonionic surfactant, a dispersant, a thickener, a pH adjuster, a texture enhancer, a colorant, an antioxidant, a chelating agent, a viscosity modifier, an antifoaming agent, a stabilizer (including a hydrotrope), an enzyme, a fragrance agent, etc., as an optional component. The amount of the optional component is the amount calculated on an effective content basis at the time of preparation of the composition, and this corresponds to the content in the composition. The content of any other optional components other than component (a), component (b), water, and component (c) in the composition of the present invention may be, for example, 30% by mass or less, 20% by mass or less, 15% by mass or less, 10% by mass or less, 5% by mass or less, 1% by mass or less, 0.5% by mass or less, or 0% by mass.

[0045] <ph> The pH of the composition of the present invention at 25°C is preferably 4.0 or higher, more preferably 4.5 or higher, and even more preferably 5.0 or higher, from the viewpoint of cleaning properties when used at dilute concentrations, and preferably 9.0 or lower, more preferably 8.5 or lower, and even more preferably 8.0 or lower, from the viewpoint of odorlessness when stored at high temperatures. If the pH exceeds 9.0, there is a risk of odor generation when stored at high temperatures. In particular, when the composition of the present invention contains component (c), there is a tendency for odor to be more likely to be generated when stored at high temperatures. The pH of the composition of the present invention at 25°C can be measured specifically by the method described in the examples.

[0046] [Uses of disinfectant and cleaning agent compositions] The composition of the present invention can be applied to disinfectant detergents where both bactericidal and cleaning properties are required when used at dilute concentrations. The composition of the present invention is preferably intended for sterilizing and cleaning hard surfaces. The hard surface is preferably the surface of hard articles in kitchens, bathrooms, and toilets. Examples of hard items in the kitchen include dishes, cutting boards, cooking utensils, dishwashers, sinks, and drains. Examples of hard surfaces in a bathroom include bathtubs, bathroom floors, bathroom walls, tiles, drains, bath chairs, bath buckets, hand showers, faucets, mirrors, and other bathroom accessories. Examples of hard materials in a toilet include the toilet bowl, toilet seat, and toilet floor.

[0047] [Method of using disinfectant cleaning agent composition] The disinfectant cleaning agent composition of the present invention is used as a disinfectant cleaning solution diluted with water at the time of use. From the viewpoint of disinfection, cleaning power and economy, the dilution ratio with water is preferably 10 times or more, more preferably 50 times or more, even more preferably 100 times or more, even more preferably 300 times or more, even more preferably 400 times or more, and preferably 10,000 times or less, more preferably 5,000 times or less, even more preferably 3,500 times or less, even more preferably 1,000 times or less, and even more preferably 800 times or less. The dilution ratio is adjusted as appropriate so that the content of component (a) in the disinfectant cleaning solution is in the range of 1 ppm to 100 ppm. The hardness of the water used for dilution is preferably 0°DH or higher, more preferably 2°DH or higher, preferably 20°DH or lower, more preferably 10°DH or lower, and even more preferably 8°DH or lower, according to German hardness. The temperature at which the disinfectant cleaning solution is used is not particularly limited, but from the viewpoint of disinfection and cleaning properties, it is preferably 30°C or higher, more preferably 40°C or higher, even more preferably 55°C or higher, and preferably 90°C or lower, and more preferably 80°C or lower. In the method of use of the present invention, rinsing with fresh water can be performed after treatment with the disinfectant cleaning solution. The temperature of the water used for rinsing is preferably 25°C or higher, more preferably 30°C or higher, even more preferably 40°C or higher, and preferably 90°C or lower, and more preferably 80°C or lower. The present invention can be used in an automatic dishwasher that can automatically adjust the aforementioned usage method. In addition to the normal dishwashing course, it can also be suitably used for cleaning the dishwasher itself using the automatic cleaning function of the automatic dishwasher. Furthermore, when determining the concentration of component (a) in the composition when diluted with water, that is, the concentration of component (a) in the composition diluted with water (also called "sterilizing cleaning solution"), by analysis, the concentration of component (a) shall be determined in the same way as the content of component (a) described above, by the anion of component (a) (the counterion (X) of the quaternary ammonium ion represented by general formula (a1)). - Even if the other component is not a chlorion, it can be calculated by converting it to a chlorine salt.

[0048] [Methods for inhibiting biofilm formation] The biofilm formation suppression method of the present invention can reduce the number of bacteria present and suppress biofilm formation when various bacterial species are present on solid surfaces of various materials by using the composition of the present invention. The biofilm formation inhibition method of the present invention is preferably applied to hard surfaces, particularly in a dishwasher. [Examples]

[0049] The present invention will be described below with reference to examples, but the present invention is not limited to the scope of these examples. In the examples, various measurements and evaluations were performed by the following methods.

[0050] [Iss] The pH of the disinfectant detergent compositions obtained in each example was measured at 25°C using a pH meter (manufactured by Horiba, Ltd.) with an electrode 6367-10D (manufactured by Horiba, Ltd.). The calibration and measurement methods were as follows: pH 4.01 standard solution (phthalate standard solution), pH 6.86 standard solution (neutral phosphate standard solution), and pH 9.18 standard solution (borate standard solution) were each filled into 100 mL beakers and left to stand in a 25°C constant temperature bath for 30 minutes. After adjusting each standard solution to a constant temperature of 25°C, a calibration procedure was performed by first immersing the pH measuring electrode in the neutral phosphate standard solution for 3 minutes, and then the same calibration procedure was performed in the order of borate standard solution and phthalate standard solution. The sample composition was filled into a 100 mL beaker and left to stand in a 25°C constant temperature bath for at least 60 minutes. The pH was then measured by immersing a pH measuring electrode in the sample, which had been adjusted to a constant temperature of 25°C, for 2 minutes.

[0051] [Bactericidal activity evaluation] The disinfectant and cleaning compositions obtained in each example were subjected to the following tests using hard water (3.5°DH hard water). <Concentration adjustment of disinfectant and cleaning agent composition> The disinfectant cleaning agent compositions obtained in each example were diluted with hard water (3.5°DH hard water) to a concentration of 0.2% by mass, and the concentration of the disinfectant cleaning agent compositions was adjusted to prepare the test solutions. Here, the concentration of component (a) in the test solutions of Examples 1-4, 9, and 11, and Formulation Examples 2-3 and 9, which were adjusted for concentration, was "20 ppm". The concentration of component (a) in the test solutions of Examples 5 and 10, and Formulation Examples 1, 4-8, which were adjusted for concentration, was "10 ppm". The concentration of component (a) in the test solution of Example 6, which was adjusted for concentration, was "30 ppm". The concentration of component (a) in the test solution of Example 7, which was adjusted for concentration, was "40 ppm". The concentration of component (a) in the test solution of Example 8, which was adjusted for concentration, was "60 ppm".

[0052] <Preparation of bacterial suspension> A bacterial suspension of Staphylococcus aureus subsp. aureus NBRC 12732 was prepared by diluting the suspension with pure water while measuring the turbidity (OD600) using a Tecan "Infinite 200 PRO" spectrophotometer until OD600 = 1.5. This prepared bacterial suspension was then used as the test bacterial suspension.

[0053] <Sterilization test> To a 1.5 mL tube (Eppendorf Tube 1.5 mL, Model No.: 0030 125.150, manufactured by Eppendorf Co., Ltd.), 1 mL of the test solution whose concentration was adjusted as described above was added, and 25 μL of the test bacterial suspension prepared as described above was added. After stirring using a vortex mixer, the tube was placed in a block incubator that had been preheated to 40°C and incubated for 10 minutes to prepare the test treated bacterial suspension. After the specified time, 100 μL of the test-treated bacterial solution prepared above was immediately added to a 1.5 mL tube containing 0.9 mL of LP diluent (LP diluent "Daigo" manufactured by Shioya MS Co., Ltd.) to inactivate the bacteria. The bacterial suspension used for the test treatment was serially diluted 10-fold with LP diluent and dispensed into 100 μL portions into petri dishes (AS ONE Corporation's Azunol petri dish, 90 mm in diameter, 15 mm in height). Approximately 15 mL of SCD agar medium was added to each, the lid was closed, and after light mixing, the mixture was left to stand at room temperature until the agar solidified. After static incubation at 37°C for 1 day, the number of remaining viable Staphylococcus aureus subsp. Aureus cells was counted using a colony counterpen (Colony Counterpen Type, Model No.: 2-5764-01, manufactured by AS ONE Corporation).

[0054] <Evaluation Criteria> The bactericidal activity value of the disinfectant cleaning agent composition was determined using the following formula. A higher bactericidal activity value indicates superior bactericidal performance. Bactericidal activity value of disinfectant cleaning agent composition = LogX - LogY X: Average number of remaining viable bacteria in the test bacterial suspension collected after the test bacterial suspension came into contact with physiological saline. Y: The average number of viable bacteria in the recovered test-treated bacterial solution after the test bacterial solution has come into contact with the test solution of the disinfectant cleaning agent composition. Furthermore, the bactericidal activity was evaluated according to the following criteria. A: A bactericidal activity value of 4 or higher was considered to indicate very high bactericidal activity. B: A bactericidal activity value of 3 or higher but less than 4 was considered to indicate high bactericidal activity. C: If the bactericidal activity value is between 2 and 3, it was evaluated that the bactericidal effect is at a level that does not pose a practical problem. D: If the bactericidal activity value was between 1 and 2, it was evaluated as having low bactericidal activity. E: If the bactericidal activity value is less than 1, it was evaluated as not having bactericidal properties.

[0055] [Evaluation of cleaning performance] The disinfectant and cleaning agent compositions obtained in each example were subjected to the following tests using tap water. <Washing Test> A ceramic plate with a diameter of 20 cm was coated with 3 g of soft-boiled egg yolk heated to 70°C in a 15 cm diameter area at the center of the plate. After drying for one day, a stain with a protein / lipid complex was created, and the plate was designated as a protein / lipid complex stained plate. On the other hand, 2.5g of a mixed oil of pork fat / rapeseed oil (1 / 1 by mass ratio) was applied to a polypropylene plate to create a plate stained with pork fat / rapeseed oil, which was then designated as a plate contaminated with mixed oil stains. Two dishes contaminated with mixed stains, two dishes contaminated with mixed oil stains, and two clean polypropylene dishes were placed one by one in an automatic dishwasher. 6g of the disinfectant detergent composition obtained in each example was added, and a washing test was conducted using the standard course with a washing solution in which the disinfectant detergent composition was diluted with tap water. Here, the concentration of component (a) in the cleaning solutions of Examples 1-4, 9, and 11, and Formulation Examples 2-3 and 9, which were subjected to the cleaning test, was "20 ppm". The concentration of component (a) in the cleaning solutions of Examples 5 and 10, and Formulation Examples 1, 4-8, which were subjected to cleaning tests, was "10 ppm". The concentration of component (a) in the cleaning solution of Example 6 used in the cleaning test was "30 ppm". The concentration of component (a) in the cleaning solution of Example 7 used in the cleaning test was "40 ppm". The concentration of component (a) in the cleaning solution of Example 8 used in the cleaning test was "60 ppm". Then, three panelists evaluated the six plates after the washing test based on their appearance and feel, assigning a score for their cleanliness according to the following criteria. (Evaluation criteria for protein / lipid complex stains) 4: The initial dirt has been completely cleaned. 3: Less than 20% of the initial dirt remains, indicating that it has been almost completely cleaned. 2: More than 20% but less than 50% of the initial adhesion remains, indicating that the cleaning is generally successful. 1: More than 50% of the initial adhesion remains, indicating that it has hardly been cleaned at all. (Evaluation criteria for mixed oil stains) 4: The dirt has been removed, and it feels pleasantly squeaky to the touch. 3: The dirt is gone, but it doesn't feel squeaky clean to the touch. 2: Most of the dirt appears to have been washed away, but streaks remain when rubbed with a finger. 1: You can see that there is still oil left. Furthermore, the evaluation scores for cleaning performance against protein / lipid complex stains and mixed oil stains were averaged, rounded to one decimal place, and an overall evaluation of cleaning performance was performed according to the following criteria. <Overall Evaluation Criteria> A: 3 points or more B: 2 points or more but less than 3 points C: More than 1 point but less than 2 points D: 1 point

[0056] [Evaluation of odor properties during high-temperature storage] The disinfectant and cleaning agent compositions obtained in each example were subjected to the following tests without any concentration adjustment. <Odor Test> A disinfectant cleaning agent composition was placed in a No. 7 screw-cap tube manufactured by Maruemu and stored in a constant-temperature bath at 50°C for one month. <Evaluation Criteria> Subsequently, the odor characteristics during high-temperature storage were evaluated from the neck of the screw-cap bottle according to the following criteria. A: No amine-based odor. B: The amine-based odor is at a level that does not pose a practical problem. C: Has a strong amine-like odor.

[0057] Examples 1-11, Comparative Examples 1-5 The amounts of each component shown in Table 1 were combined and mixed at room temperature. Then, a 1 mol / L aqueous hydrochloric acid solution and / or a 1 mol / L aqueous sodium hydroxide solution were used as pH adjusters to adjust the pH to the values ​​shown in Table 1. Finally, ion-exchanged water was added as the remainder to a total of 100 parts by mass to prepare the disinfectant cleaning agent composition shown in Table 1. The evaluation results for the bactericidal properties, cleaning properties, and odor properties during high-temperature storage of the obtained disinfectant cleaning agent composition are shown in Table 1.

[0058] Formulation examples 1~9 The disinfectant and cleaning agent compositions shown in Table 2 were prepared using the same method as in Example 1.

[0059] [Table 1]

[0060] [Table 2]

[0061] [Ingredients] The components used in the examples and comparative examples shown in Table 1, and the formulation examples shown in Table 2, are as follows. Note that the amounts listed in Tables 1 and 2 represent the amount of active ingredient (mass%) for each component. <(a) Components> a-1 Dioctyldimethylammonium chloride :In general formula (a1), R 1a and R 2a R is a linear alkyl group with 8 carbon atoms, 3a and R 4a The group is a methyl group, X - A compound in which chlorine ions are present, with a molecular weight (Mw) of 306. a-2 Dioctylethylmethylammonium ethyl sulfate :In general formula (a1), R 1a and R 2a R is a linear alkyl group with 8 carbon atoms, 3a is an ethyl group, R 4a The group is a methyl group, X - A compound in which ethyl sulfate ions are present, molecular weight (Mw) 410 <(a') component (comparison component of (a))> a'-1 Didecylethylmethylammonium ethyl sulfate :In general formula (a1), R 1a and R 2a is an alkyl group having 10 carbon atoms, and R 3a is an ethyl group, R 4a The group is a methyl group, X - A compound in which ethyl sulfate ions are present, "Cotamin D-10ES" manufactured by Kao Corporation, molecular weight (Mw) 466 a'-2 Benzalkonium chloride Kao Corporation's "Sanisol C," a linear alkylbenzyldimethylammonium chloride with 8-16 carbon atoms in the alkyl group, molecular weight (Mw) 340. <(b) Component> b-1 Sodium Decyl Sulfate Kao Corporation's "Emal 3F", molecular weight (Mw) 260 b-2 Sodium di-(2-propylheptyl)sulfosuccinate Manufactured by Kao Corporation, molecular weight (Mw) 501 b-3 1-Sodium dodecylsulfonate Reagent manufactured by Tokyo Chemical Industry Co., Ltd., molecular weight (Mw) 272 b-4 Sodium dodecylbenzenesulfonate Reagent manufactured by Sigma-Aldrich Co., Ltd., molecular weight (Mw) 348 b-5 Sodium di-(2-ethylhexyl) sulfosuccinate Manufactured by Kao Corporation, molecular weight (Mw) 395 <(c) component> c-1 Monoethanolamine Monoethanolamine, manufactured by Mitsui Chemicals, Inc., molecular weight (Mw) 61 <(d) component> d-1 Polyoxyethylene (4) lauryl ether Kao Corporation's "Emulgen 105" d-2 Polypropylene glycol Polypropylene glycol triol type (weight-average molecular weight 3,000), reagent manufactured by Fujifilm Wako Pure Chemical Industries, Ltd. d-3 Xanthan gum Reagent manufactured by Tokyo Chemical Industry Co., Ltd. d-4 Polyacrylic acid Sumitomo Seika Co., Ltd. Akpec HV-701EDR d-5 Polyacrylic acid / maleic acid copolymer Acrylic acid / maleic acid copolymer salt (weight-average molecular weight 20,000, molar ratio of acrylic acid to maleic acid = 7 / 3, sodium salt), manufactured by Kao Corporation. d-6 Citric Acid Reagent manufactured by Fujifilm Wako Pure Chemical Corporation d-7 L-Glutamate diacetate tetrasodium Made by Nouryon d-8 Sodium cumenesulfonate : Teika Co., Ltd.'s "Teika Tox N5040" d-9 1-decanol Reagent manufactured by Tokyo Chemical Industry Co., Ltd. d-10 Enzyme (Amylase) Novozymes "Amplify Prime 100L" d-11 Enzyme (Protease) :Novozymes "Progress Uno 100L"

[0062] The results shown in Table 1 confirm the following: It was confirmed that the disinfectant cleaning agent compositions of Examples 1 to 11, when used at dilute concentrations, provided a bactericidal effect even when the molar ratio of component (a) to component (b), (a) / (b), was less than 1. In particular, the disinfectant cleaning agent compositions of Examples 10 to 11, which contained component (c), were confirmed to have a very excellent bactericidal effect when used at dilute concentrations. Furthermore, it was confirmed that the disinfectant cleaning agent compositions of Examples 1 to 11, when used at dilute concentrations, were perfectly adequate for practical use in terms of cleaning performance. Furthermore, it was confirmed that the disinfectant and cleaning agent compositions of Examples 1 to 11 produced less odor when stored at high temperatures. On the other hand, it was confirmed that the disinfectant and cleaning agent compositions of Comparative Examples 1 to 5, when used at dilute concentrations, exhibited inferior disinfecting and cleaning properties compared to Examples 1 to 11. [Industrial applicability]

[0063] According to the present invention, it is possible to provide a disinfectant and cleaning agent composition that excels in achieving both bactericidal and cleaning properties when used at dilute concentrations.< / ph>

Claims

1. A disinfectant cleaning agent composition containing the following components (a), (b), and water, wherein the molar ratio of component (a) to component (b), (a) / (b), is 0.05 or more and less than 1, The concentration of component (a) in the disinfectant cleaning agent composition when diluted with water is 1 ppm or more and 100 ppm or less. A disinfectant and cleaning agent composition. (a) Component: Compound represented by the following general formula (a1) 【Chemistry 1】 (In general formula (a1), R １ａ and R ２ａ Each of these is independently a linear or branched alkyl group having 8 carbon atoms, and R ３ａ and R ４ａ Each of these is independently a linear or branched alkyl group having 1 to 3 carbon atoms, and X － It is an anion. (b) Component: An anionic surfactant having one or more selected from a sulfonic acid group, a sulfate ester group, and salts of these substituents.

2. The disinfectant cleaning agent composition according to claim 1, wherein the pH at 25°C is 5.0 or higher and 8.5 or lower.

3. The disinfectant cleaning composition according to claim 1, wherein component (b) is one or more selected from alkyl sulfonates, alkyl sulfates, (di)alkyl sulfosuccinates, alkylbenzene sulfonates, internal olefin sulfonates, α-olefin sulfonates, α-sulfo fatty acid esters, and alkyl ether sulfates, having a linear or branched alkyl group having 6 to 20 carbon atoms.

4. Furthermore, the disinfectant cleaning agent composition according to claim 1, further comprising the following component (c). (c) Components: Organic amines

5. (c) The disinfectant cleaning agent composition according to claim 4, wherein the component is an alkanolamine.

6. The disinfectant cleaning agent composition according to claim 4, wherein the molar ratio of the total of components (a) and (c) to component (b) [(a) + (c)] / (b) is 1 or more and 20 or less.

7. A disinfectant cleaning agent composition according to claim 1, for use on hard surfaces.

8. The disinfectant cleaning agent composition according to claim 7, wherein the hard surface is a kitchen, bathroom, or toilet.

9. A method for inhibiting biofilm formation using the bactericidal cleaning agent composition described in any one of claims 1 to 8.

10. A method for inhibiting biofilm formation according to claim 9, performed inside a dishwasher.

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