Histotripsy System and Method

The ultrasonic treatment head with a therapy transducer array and imaging probe addresses the limitations of thermal ablation by using mechanical cavitation for precise tissue disruption with clear ultrasound imaging, enhancing treatment control and visibility.

JP2026500772APending Publication Date: 2026-01-08HISTOSONICS INC
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Patent Information

Application Number
JP2025538438
Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
Priority Date
2022-12-30
Filing Date
2023-04-14
Publication Date
2026-01-08

AI Technical Summary

Technical Problem

Existing thermal ablation techniques for tissue treatment rely on heat, cryo, or ionizing energy, lacking precision and visibility, while Histotripsy, which uses mechanical cavitation, offers controlled and precise tissue destruction with ultrasound imaging confirmation.

Method used

An ultrasonic treatment head with a therapy transducer array and an imaging probe, featuring a coupling assembly with exhaust holes to expel air bubbles and channels to direct them away, ensuring clear imaging and efficient fluid removal.

Benefits of technology

Enables precise and controlled tissue disruption with real-time ultrasound imaging confirmation, avoiding thermal damage and clutter-free operation.

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Abstract

Histotripsy therapy systems configured for the treatment of tissue are provided, which may include any number of features. Provided herein are systems and methods for providing effective, non-invasive and minimally invasive therapeutic, diagnostic, and research procedures. In particular, provided herein are systems and methods for acoustically coupling a histotripsy therapy system to a patient's epidermis to provide targeted, effective histotripsy in a variety of different regions and for a variety of different conditions without causing undesired tissue damage to intervening / non-target tissues or structures.
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