Syringe needle ejection device and injection test system

Abstract

An exemplary needle blowout device is disclosed that includes a mounting surface having a first side configured to contact a syringe and a second side opposite the first side, an adjustable blowout nozzle adjacent the second side of the mounting surface, the adjustable blowout nozzle including a gas inlet configured to be coupled to a gas source, and a gas outlet configured to direct gas from the gas inlet toward a location of the syringe needle, the gas outlet being adjustable to blow against the needle within a range of distances from the second side of the mounting surface.

Description

[Technical Field]

[0001] FIELD OF THE DISCLOSURE The present disclosure relates generally to testing of injection devices, and more particularly to needle blowout apparatus and injection testing systems. [Background technology]

[0002] The injection testing system can test one or more aspects of an injection device, including an auto-injector, for aspects such as cap removal force, plunger actuation force, injection depth, needle retraction, and / or delivered dose. Summary of the Invention

[0003] A needle blowout device and injection test system is disclosed, as more fully set forth in the claims, substantially as shown in and described with reference to at least one of the drawings. [Brief explanation of the drawings]

[0004] These and other features, aspects, and advantages of the present disclosure will be better understood when the following detailed description is read in conjunction with the accompanying drawings, in which like reference characters represent like parts throughout.

[0005] [Figure 1] FIG. 1 illustrates an exemplary injection testing system for performing testing of injection devices, according to aspects of the present disclosure.

[0006] [Figure 2] FIG. 1 is a block diagram of an exemplary injection test system including a needle blowout device, according to aspects of the present disclosure.

[0007] [Figure 3] 3 is a perspective view of an exemplary embodiment of the elements of the injection test system of FIG. 2.

[0008] [Figure 4]4 is a perspective view of the exemplary needle blowout device of FIG. 3 with a positioning plate and a blowout nozzle. FIG.

[0009] [Figure 5] FIG. 4 is a front view of the exemplary needle blowout device of FIG. 3.

[0010] [Figure 6] FIG. 4 is a bottom view of the exemplary needle blowout device of FIG. 3.

[0011] [Figure 7A] 4 is a different perspective view of the exemplary needle blowout device of FIG. 3. [Figure 7B] 4 is a different perspective view of the exemplary needle blowout device of FIG. 3.

[0012] [Figure 8] 4 is a front cross-sectional view of the exemplary needle blowout device of FIG. 3.

[0013] [Figure 9A] 10A-10C illustrate another exemplary embodiment of the blow-out nozzles, each having an adjustable distance from the tip of the needle in a direction parallel to the needle.

[0014] [Figure 9B] 10 illustrates another exemplary embodiment of the blow-off nozzles, each having an adjustable angle for adjusting the angle of the gas outlet relative to the bottom surface of the positioning plate. FIG.

[0015] The drawings are not necessarily to scale. Where appropriate, like or identical reference numbers are used to refer to like or identical components. DETAILED DESCRIPTION OF THE INVENTION

[0016] Needle testing devices for measuring doses delivered by injection needles, particularly auto-injectors, include a flask or other container positioned to capture and measure the fluid expelled from the needle. To accurately measure the expelled fluid, the needle testing device may include a puff or other method for isolating the final amount of expelled fluid, which may tend to remain attached to the needle due to fluid adhesion. While injection devices can have a wide range of shapes and sizes, conventional needle testing devices are limited in the range of needle lengths that can be tested, at least in part due to the structure of the puff device. Changing the needle length being tested can involve a relatively lengthy process of changing the puff.

[0017] The disclosed exemplary needle blowout devices and injection testing systems allow for a wider range of needle lengths to be tested using the same blowout device. In some disclosed examples, the exposed needle length that can be tested is 2 mm or greater, which includes blowing off the last droplet of fluid emitted from the needle. In some examples, the position(s) and / or orientation(s) of one or more blowout nozzles are adjustable relative to the needle position. By adjusting the position(s) and / or orientation of the blowout nozzle(s), the location at which gas is delivered by the blowout nozzle(s) can be tailored to the needle length and the resulting location at which the last droplet of ejected fluid appears.

[0018] An exemplary injection needle blow-off device is disclosed that includes a mounting surface having a first side configured to contact an injector and a second side opposite the first side, and an adjustable blow-off nozzle adjacent the second side of the mounting surface, the adjustable blow-off nozzle including a gas inlet configured to be coupled to a gas source, and a gas outlet configured to direct gas from the gas inlet toward the location of the syringe needle, the gas outlet being adjustable to blow against the needle within a range of distances from the second side of the mounting surface.

[0019] In some example needle blow-out devices, the adjustable blow-out nozzle is configured to have an adjustable distance from the opening along a plane of the second side of the mounting surface, and in some example needle blow-out devices, the gas outlet is configured to blow at an angle away from the second side of the mounting surface, and the gas outlet is configured to blow against the needle at a location based on the distance between the adjustable blow-out nozzle and the needle in a plane perpendicular to the needle.

[0020] In some exemplary needle blowout devices, the adjustable blowout nozzle is configured to have an adjustable distance from the tip of the needle in a direction parallel to the needle. In some exemplary needle blowout devices, the mounting surface includes a positioning plate having an opening extending from a first side of the positioning plate to a second side of the positioning plate. In some exemplary needle blowout devices, the adjustable blowout nozzle is positioned on the first side of the opening, and the needle blowout device further includes a second adjustable blowout nozzle positioned on the second side of the opening. In some exemplary needle blowout devices, the second adjustable blowout nozzle includes a second gas inlet configured to be coupled to a gas source and a second gas outlet configured to direct gas toward the location on the needle, the second gas outlet being adjustable to blow against the needle within a range of distances. In some exemplary needle blowout devices, the opening has at least one dimension smaller than a corresponding dimension of the body of the syringe.

[0021] In some exemplary needle blow-out devices, the adjustable blow-out nozzle is configured to have an adjustable angle of the gas outlet. In some exemplary needle blow-out devices, the adjustable blow-out nozzle comprises a body defining a channel between a gas inlet and a gas outlet, the channel configured to increase at least one of a flow rate of the gas or a pressure of the gas between the gas inlet and the gas outlet. Some exemplary needle blow-out devices further comprise control circuitry configured to automatically control the blow-out actuator to adjust the location of the blow-out nozzle.

[0022] Some disclosed syringe testing devices include a gas supply source and a needle blow-out device, the needle blow-out device comprising: a mounting surface having a first side configured to contact a syringe and a second side opposite the first side; an adjustable blow-out nozzle adjacent to the second side of the mounting surface, the adjustable blow-out nozzle comprising: a gas inlet configured to be coupled to the gas supply source; and a gas outlet configured to direct gas from the gas inlet toward a location of the syringe needle, the gas outlet being adjustable to blow against the needle within a range of distances from the second side of the mounting surface; and control circuitry configured to control the gas supply source to discharge gas into the adjustable blow-out nozzle.

[0023] Some example syringe testing devices further include a syringe positioner configured to position the syringe, and the control circuitry is configured to control the syringe positioner to position the syringe. In some example syringe testing devices, the syringe positioner is configured to move the body of the syringe into contact with the mounting surface.

[0024] Some example syringe testing devices further include a syringe actuator configured to actuate the syringe to expel the contents of the syringe through the needle while the needle is adjacent to the adjustable discharge nozzle, and the control circuitry is configured to control the syringe actuator to actuate the syringe. In some example syringe testing devices, the syringe actuator is configured to actuate the syringe when the body of the syringe is in contact with the mounting surface.

[0025] Some example syringe testing devices further include a collection container configured to collect contents expelled from the syringe. In some example syringe testing devices, the mounting surface includes a positioning plate having an opening extending from a first side of the positioning plate to a second side of the positioning plate, the adjustable blow-out nozzle configured to have an adjustable distance from the opening along a plane of the second side of the positioning plate, the gas outlet configured to blow at an angle away from the second side of the positioning plate, and the gas outlet configured to blow against the needle at the location based on a distance between the adjustable blow-out nozzle and the opening in a direction parallel to the second side of the positioning plate.

[0026] In some exemplary syringe testing devices, the adjustable blow-out nozzle is configured to have an adjustable distance from the tip of the needle in a direction parallel to the needle. Some exemplary syringe testing devices further include a second adjustable blow-out nozzle configured to direct gas toward the needle. In some exemplary syringe testing devices, the gas source includes a compressed gas source, an air pressure pump, or a blower.

[0027] 1 illustrates an example injection test system 100 for performing tests on an injection device, such as an auto-injector 102. The example injection test system 100 may be configured to perform some or all of the tests to evaluate the requirements of the ISO 11608-5 standard, for example. The example injection test system 100 may be, for example, a general-purpose test system configured for injection testing.

[0028] 1 includes positioning device(s) (e.g., to position the auto-injector 102 in one or more positions and / or orientations for automated testing), actuator(s) (e.g., to actuate components of the auto-injector 102, actuate the positioning device(s), position and / or orient a test device, etc.), and / or sensors that measure aspects of the auto-injector 102 during testing (e.g., load sensors that measure actuation force(s), audio sensors that detect audible events, mass scales that measure ejection amounts, displacement and / or position sensors that initiate test steps and / or measure displacement of components of the auto-injector 102, etc.). The example injection test system 100 further includes one or more user interface devices, such as displays 104a, 104b and input devices 106.

[0029] 2 is a block diagram of an example injection test system 200 including a needle blowout device. The example injection test system 200 can be used to implement some or all of the components of the injection test system 100 of FIG.

[0030] The exemplary injection test system 200 includes a syringe positioner 202, a syringe actuator 204, an injection collector 206, and control circuitry 208. The syringe positioner 202 positions and / or orients a syringe 210 (e.g., an auto-injector) for one or more tests in the injection test system 200. For example, the syringe positioner 202 may grip the syringe 210 and move and / or rotate the syringe 210 for testing. The position of the syringe positioner 202 and / or the syringe 210 may be measured by one or more displacement sensors 212, which provide displacement and / or position information to the control circuitry 208.

[0031] The syringe actuator 204 actuates one or more aspects of the syringe 210, such as the plunger or other injection mechanism of the syringe 210. The force applied by the syringe actuator 204 can be measured by a force sensor 214, which provides a force measurement to the control circuitry 208.

[0032] The syringe collector 206 includes a mounting surface (e.g., a positioning plate 216), a discharge nozzle 218, and a collection container 220. The collection container 220 and syringe 210 are positioned such that actuation of the syringe 210 to expel fluid contained within the syringe 210 expels the fluid into the collection container 220. A collection sensor 222 measures the mass and / or volume collected in the collection container 220 and provides the mass or volume measurement to the control circuitry 208.

[0033] The positioning plate 216 allows the needle 224 of the syringe 210 to extend therethrough toward the collection container 220. The positioning plate 216 can block the body 225 of the syringe 210 from extending therethrough using an opening appropriately sized for the needle 224 and the body 225 of the syringe 210. To test for delivery of the contained fluid, the syringe positioner 202 can position the syringe 210 so that it contacts or abuts the positioning plate 216, with the needle 224 extending through the opening in the positioning plate 216. Once the syringe 210 is positioned, the syringe 210 can be actuated (e.g., manually or automatically via the syringe actuator 204) to expel the contents of the syringe 210 into the collection container 220.

[0034] While the examples disclosed herein use the positioning plate 216 as a loading surface, other examples may use a different type of loading surface such that the syringe 210 can be actuated to expose the needle 224 to the loading surface and / or release the contents of the syringe 210 onto the loading surface. For example, a rod or other structural member may be used that contacts the body of the syringe 210 on the top side of the loading surface and is positioned so as not to obstruct the needle 224. In some such examples, the blow nozzle 218 may be coupled to or otherwise adjustably supported on another surface adjacent the bottom side of the loading surface and / or adjacent the location of the needle 224 within the syringe collector 206.

[0035] Upon completion of actuation of syringe 210, blow-out nozzle 218 is controlled to blow the last droplets of fluid from at or near the tip of the needle into collection container 220. Gas source 226 supplies a gas, such as nitrogen or air, to blow-out nozzle 218. Gas source 226 may be, for example, a compressed gas source, an air pressure pump, or a blower. Blowing nozzle 218 may be positioned and / or oriented to adjust the location at which the blow-out gas impinges on needle 224 and / or may be positioned and / or oriented to impinge the blow-out gas on needle 224 over a range of the needle's length.

[0036] The example control circuitry 208 can be a general-purpose computer, a laptop computer, a tablet computer, and / or any other type of processing system configured to communicate with the sensors and actuators of the injection test system 200. For example, the control circuitry 208 includes a processor 228, a memory 230, and a storage device 232. The example processor 228 can be any general-purpose central processing unit (CPU) from any manufacturer. In some other examples, the processor 228 may include one or more special-purpose processing units, such as a RISC processor with an ARM core, a graphics processing unit, a digital signal processor, and / or a system-on-a-chip (SoC). The processor 228 executes machine-readable instructions 234, which can be stored locally to the processor (e.g., in an included cache or within the SoC), in memory (e.g., random access memory or other volatile memory, read-only memory or other non-volatile memory such as flash memory), and / or in the storage device 232. Exemplary storage devices 232 may be hard drives, solid-state storage drives, hybrid drives, RAID arrays, and / or any other mass data storage devices.

[0037] Figure 3 is a perspective view of one exemplary embodiment of the exemplary syringe collector 206 of Figure 2. The syringe collector 206 includes a housing 302 within which are disposed a positioning plate 216, a blow-out nozzle 218, and a mass scale 304 (e.g., collection sensor 222 of Figure 2). Figure 4 is a perspective view of the exemplary needle blow-out device of Figure 3 including the positioning plate 216 and the blow-out nozzle 218. Figure 5 is a front view of the exemplary needle blow-out device of Figure 2.

[0038] Positioning plate 216 is positioned below the top of housing 302 so that the top surface of positioning plate 216 is accessible through housing 302 by syringe 210. Positioning plate 216 is coupled to housing 302 and may be interchanged with other positioning plates for testing different types of syringes (e.g., having different needle lengths and different body dimensions). While blow nozzle 218 is adjustable as disclosed in more detail below, interchangeability of positioning plate 216 and attached blow nozzle 218 can allow for more rapid changes to accommodate different testing procedures for different syringes.

[0039] The blow-out nozzle 218 is coupled to a bottom surface 308 of the positioning plate 216 on an opposite side of the opening 306 in the positioning plate 216. The needle 224 of the syringe 210 extends through the opening 306 and protrudes into the bottom side of the positioning plate 216. When the syringe 210 is actuated, fluid is expelled from the needle 224 into the collection container 220 (e.g., positioned on the mass scale 304 below the needle 224).

[0040] 5, at the end of fluid ejection, the last remaining amount of fluid tends to adhere to needle 224 in the form of droplets 502. After actuation is complete, control circuitry 208 controls gas source 226 and / or blow-out nozzle 218 (e.g., via a valve or other control device) to blow gas 504 towards needle 224 and remove droplets 502 into collection container 220.

[0041] Figure 6 is a bottom view of the exemplary needle blowout device of Figure 2. Figures 7A and 7B are different perspective views of the exemplary needle blowout device of Figure 3 including positioning plate 216 and blowout nozzle 218.

[0042] The example blow-out nozzles 218 each include a gas inlet 702 that is coupled via a hose or other connection to the gas source 226. As shown in Figures 7A and 7B, the blow-out nozzles 218 also include a gas outlet 704 that directs gas received via the corresponding gas inlet 702 toward the location of the needle 224.

[0043] 7A and 7B direct gas at least partially away from the bottom surface of the positioning plate 316. Additionally, the blow-out nozzles 218 are adjustable such that the gas outlets 704 can be adjusted to direct gas 504 toward the tips of the needles 224 for various needle lengths. In the example of FIGS. 4-7B, the blow-out nozzles 218 have an adjustable distance (e.g., toward and away from the openings 306 in the positioning plate 216) along the plane of the bottom surface 308 of the positioning plate 216 (e.g., in a plane parallel to the bottom surface of the positioning plate 216 and perpendicular to the needles 224). To this end, each blow-out nozzle 218 includes a slot 602, a screw 604, and a dowel 606 to allow adjustment of the position of the blow-out nozzle 218 and to secure the blow-out nozzle 218 in a desired position.

[0044] The screw 604 extends through the slot 602 and into a threaded hole in the positioning plate 216. The slot 602 extends in an adjustment direction for the blow-out nozzle 218 such that when the screw 604 is loosened from the positioning plate 216, the blow-out nozzle 218 moves toward and away from the opening 306. Once the blow-out nozzle 218 is positioned in a desired location, the screw 604 can be tightened to clamp the blow-out nozzle 218 to the positioning plate 216. The illustrated screw 604 may be replaced with a dowel extending from the positioning plate 216 into the slot 602 and a different clamping mechanism, such as a clamp or clip coupled to the positioning plate 216, to clamp or otherwise secure the blow-out nozzle 218 in the desired position.

[0045] The dowel 606 extends from the blow-out nozzle 218 into a corresponding slot in the positioning plate 216. The slot in the positioning plate 216 extends parallel to the slot 602 in the blow-out nozzle 218 and limits rotation of the blow-out nozzle 218 (e.g., to maintain the gas outlet 704 directed toward the needle 224). The dowel 606 may be replaced with another rotation-limiting device, such as a bracket coupled to the positioning plate 216 adjacent the blow-out nozzle 218, to limit rotation and / or guide movement of the blow-out nozzle 218. In some examples, the blow-out nozzle 218 may be coupled to one or more respective worm gears, rack-and-pinion gears, and / or other gear systems that can then be actuated to adjust the positioning of the blow-out nozzle 218.

[0046] Figure 8 is a front cross-sectional view of the example blow-off nozzle 218 of Figures 4-7B. As shown in Figure 8, the example blow-off nozzle 218 includes a passageway 802 extending from a gas inlet 702 to a gas outlet 704. The cross-sectional area of ​​the passageway 802 decreases from the gas inlet 702 to the gas outlet 704 to increase the velocity of the gas 504.

[0047] 8 , the passageway 802 directs the gas 504 at least partially away from the bottom surface 308 of the positioning plate 216 as the gas 504 exits the gas outlet 704. As the blow-out nozzle 218 and gas outlet 704 are adjusted closer to the needle 224 (e.g., via the threads 604 and slots 602), the distance between the bottom surface 308 and the location on the needle 224 decreases due to the angle of the passageway 802 at the gas outlet 704. Conversely, as the blow-out nozzle 218 and gas outlet 704 are adjusted farther from the needle 224, the distance between the bottom surface 308 and the location on the needle 224 increases.

[0048] The example blow-off nozzle 218 may be constructed using additive manufacturing or 3D printing and / or using conventional subtractive manufacturing techniques to form the passageway 802.

[0049] 9A shows another exemplary embodiment of the blow-out nozzles 218, each having an adjustable distance from the tip of the needle 224 in a direction parallel to the needle 224 (e.g., an adjustable distance from the bottom surface 308 of the positioning plate 216). In the example of FIG. 9A, the blow-out nozzles 218 include a gas inlet 702 and a gas outlet 704. Instead of, or in addition to, being adjustable in a direction parallel to the bottom surface 308 of the positioning plate 216, the blow-out nozzles of FIG. 9A are adjustable along a dowel 902 parallel to the exemplary needle 224. Once the blow-out nozzles 218 are adjusted to a desired position, a set screw 904 can secure the blow-out nozzles 218 at a desired distance from the bottom surface 308. The location where the gas 504 contacts the needle 224 is adjusted by adjusting the position of the blow-out nozzles 218.

[0050] In some other examples, instead of a dowel, a helical rod or other support structure may be used to support the blow-off nozzle 218. The set screw 904 may likewise be replaced with a pin, clamp, or other fastening device.

[0051] 9B shows another exemplary embodiment of the blow-out nozzles 218, each having an adjustable angle for adjusting the angle of the gas outlets 704 relative to the bottom surface of the positioning plate 216. In the example of FIG. 9B, the blow-out nozzles 218 include a gas inlet 702 and a gas outlet 704.

[0052] 9B is coupled to the positioning plate 216 by a ball-and-socket joint 906 or other rotary joint, such as a hinge. In some examples, the ball-and-socket joint 906 may be geared or otherwise controlled to set the blow-off nozzle 218 at a desired angle. The angle of the gas outlet 704 and the gas 504, and therefore the location on the needle 224 where the gas 504 meets the needle 224, can be adjusted by adjusting the angle of the blow-off nozzle 218.

[0053] 5 and 8, the thickness T of the positioning plate 216 is reduced in a region 506 around the opening 306 compared to the remainder of the positioning plate 216. By reducing the thickness in region 506 and / or adjusting the position of the blow-out nozzle 218 relative to the opening 306, the range of needle lengths that can be tested is increased. For example, the exemplary positioning plate 216 and blow-out nozzle 218 can be used to perform tests (measuring the exposed length of the needle 224) on needle lengths up to 2 mm in length.

[0054] The example blow nozzle 218 disclosed herein may be adjusted manually or automatically. For example, the blow nozzle 218 may be coupled to a motor, gear system, and / or other actuation device to control the positioning and / or orientation of the blow nozzle 218. In some examples, the injection test system 200 may include a needle detection sensor, such as an image sensor 236, that determines the length of the needle 224 and / or the location of the tip of the needle 224. For example, the image sensor 236 may determine the location of the tip of the needle 224 by analyzing an image of the positioned needle 224. Based on the determined tip, the control circuitry 208 automatically controls the position and / or orientation of the blow nozzle 218 using a blow actuator 238 coupled to the blow nozzle 218 to direct the gas 504 toward the location of the tip of the needle 224.

[0055] In the example shown, there are two blow-out nozzles on opposite sides of the needle, but in other examples there may be a single blow-out nozzle, or three or more blow-out nozzles.

[0056] The methods and systems can be implemented in hardware, software, and / or a combination of hardware and software. The methods and / or systems can be implemented centrally in at least one computing system, or distributed, with different elements distributed across several interconnected computing systems. Any type of computing system or other device adapted to perform the methods described herein is suitable. A typical combination of hardware and software can include a general-purpose computing system, along with a program or other code that, when loaded and executed, controls the computing system to perform the methods described herein. Another typical embodiment can include an application-specific integrated circuit or chip. Some embodiments can include a non-transitory machine-readable (e.g., computer-readable) medium (e.g., a flash drive, optical disk, magnetic storage disk, etc.) that stores one or more lines of machine-executable code, thereby causing the machine to perform a process as described herein. As used herein, the term "non-transitory machine-readable medium" is defined to include all types of machine-readable storage media and to exclude propagating signals.

[0057] As used herein, the terms "circuit" and "circuitry" refer to physical electronic components (i.e., hardware) and any software and / or firmware ("code") that can comprise, be executed by, and / or otherwise be associated with hardware. As used herein, for example, a particular processor and memory can include a first "circuit" when executing a first one or more lines of code, and can include a second "circuit" when executing a second one or more lines of code. As used herein, "and / or" refers to any one or more of the items in the list connected by "and / or." As an example, "x and / or y" refers to any element of the triplet {(x), (y), (x, y)}. In other words, "x and / or y" means "one or both of x and y." As another example, "x, y, and / or z" means any element of the seven-element set {(x), (y), (z), (x,y), (x,z), (y,z), (x,y,z)}. In other words, "x, y, and / or z" means "one or more of x, y, and z." As used herein, the term "exemplary" means serving as a non-limiting example, instance, or illustration. As used herein, the term "for example" begins a list of one or more non-limiting examples, instances, or illustrations. As used herein, circuitry is "operable" to perform a function whenever it includes the necessary hardware and code (if either is necessary) to perform that function, regardless of whether implementation of that function is disabled or enabled (e.g., by a user-configurable setting, factory trim, etc.).

[0058] Although the present method and / or system has been described with reference to certain specific embodiments, those skilled in the art will recognize that various modifications and equivalent substitutions may be made without departing from the scope of the present method and / or system. For example, blocks and / or components of the disclosed examples may be combined, divided, rearranged, and / or otherwise modified. In addition, many modifications may be made to adapt a particular situation or material to the teachings of the present disclosure without departing from the scope of the present disclosure. Therefore, the present method and / or system is not limited to the particular embodiments disclosed. Instead, the present method and / or system includes all embodiments falling within the scope of the appended claims, both literally and under the doctrine of equivalents.

Claims

1. A needle blowout device, comprising: a mounting surface having a first side configured to contact a syringe and having a second side opposite the first side; an adjustable outlet nozzle adjacent the second side of the mounting surface, a gas inlet configured to be coupled to a gas source; a gas outlet configured to direct gas from the gas inlet toward a location of the syringe needle, the gas outlet being adjustable to blow against the needle within a range of distances from the second side of the mounting surface; an adjustable outlet nozzle comprising: A syringe needle ejection device comprising:

2. 10. The needle blowout device of claim 1, wherein the adjustable blowout nozzle is configured to have an adjustable distance from the opening along a plane of the second side of the mounting surface.

3. 3. The needle blowout device of claim 2, wherein the gas outlet is configured to blow at an angle away from the second side of the mounting surface, and the gas outlet is configured to blow at the needle at the location based on a distance between the adjustable blowout nozzle and the needle in a plane perpendicular to the needle.

4. 10. The needle blowout device of claim 1, wherein the adjustable blowout nozzle is configured to have an adjustable distance from the tip of the needle in a direction parallel to the needle.

5. 10. The needle blowout device of claim 1, wherein the mounting surface comprises a positioning plate having an opening therein, the opening extending from a first side of the positioning plate to a second side of the positioning plate.

6. 6. The needle blowout device of claim 5, wherein the adjustable blowout nozzle is positioned on a first side of the opening, and the needle blowout device further comprises a second adjustable blowout nozzle positioned on a second side of the opening.

7. The second adjustable outlet nozzle comprises: a second gas inlet configured to be coupled to the gas source; a second gas outlet configured to direct the gas toward the location of the needle, the second gas outlet being adjustable to blow against the needle within the distance; 7. The needle blowout device of claim 6, comprising:

8. The needle blowout device of claim 5 , wherein the opening has at least one dimension that is smaller than a corresponding dimension of the syringe body.

9. 10. The needle blowout device of claim 1, wherein the adjustable blowout nozzle is configured with an adjustable angle of the gas outlet.

10. 10. The needle blowout device of claim 1, wherein the adjustable blowout nozzle comprises a body defining a channel between the gas inlet and the gas outlet, the channel configured to increase at least one of a flow rate of the gas or a pressure of the gas between the gas inlet and the gas outlet.

11. 10. The needle blowout device of claim 1, further comprising a control circuitry configured to automatically control a blowout actuator to adjust the location of the blowout nozzle.

12. 1. A syringe testing device comprising: a gas supply source; 1. A needle blowout device, comprising: a mounting surface having a first side configured to contact a syringe and having a second side opposite the first side; an adjustable outlet nozzle adjacent the second side of the mounting surface, a gas inlet configured to be coupled to the gas source; a gas outlet configured to direct gas from the gas inlet toward a location of the syringe needle, the gas outlet being adjustable to blow against the needle within a range of distances from the second side of the mounting surface; an adjustable outlet nozzle comprising: control circuitry configured to control the gas source to discharge the gas to the adjustable outlet nozzle; a syringe needle blowout device comprising: A syringe testing device comprising:

13. 13. The syringe testing device of claim 12, further comprising a syringe positioner configured to position the syringe, the control circuitry configured to control the syringe positioner to position the syringe.

14. 14. The syringe testing device of claim 13, wherein the syringe positioner is configured to move the body of the syringe into contact with the resting surface.

15. 13. The syringe testing device of claim 12, further comprising a syringe actuator configured to actuate the syringe to expel the contents of the syringe through the needle while the needle is adjacent to the adjustable discharge nozzle, and the control circuitry configured to control the syringe actuator to actuate the syringe.

16. 16. The syringe testing device of claim 15, wherein the syringe actuator is configured to actuate the syringe when the body of the syringe is in contact with the mounting surface.

17. The syringe testing device of claim 12, further comprising a collection vessel configured to collect the contents expelled from the syringe.

18. 12. The syringe needle test device of claim 11, wherein the mounting surface comprises a positioning plate having an opening extending from a first side of the positioning plate to a second side of the positioning plate, the adjustable blow-out nozzle configured to have an adjustable distance from the opening along a plane of the second side of the positioning plate, the gas outlet configured to blow at an angle away from the second side of the positioning plate, and the gas outlet configured to blow against the needle at the location based on the distance between the adjustable blow-out nozzle and the distance from the opening in a direction parallel to the second side of the positioning plate.

19. 12. The syringe testing device of claim 11, further comprising a second adjustable blow-out nozzle configured to direct gas toward the needle.

20. 12. The syringe testing device of claim 11, wherein the gas source comprises a compressed gas source, a pneumatic pump, or a blower.

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