Cooling device and multi-functional cooling system for biological samples
The biological sample cooling device addresses rapid cooling issues by using a cavity unit and circulating cooling unit to adjust temperature gradients, ensuring stable and efficient storage of biological samples.
Patent Information
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- SHANGHAI ORIGINCELL BIOLOGICAL CRYO EQUIP CO LTD
- Filing Date
- 2024-06-25
- Publication Date
- 2026-05-25
AI Technical Summary
Conventional methods for cooling biological samples lack automated temperature control and gentle cooling gradients, leading to potential damage from rapid temperature changes and inefficient storage.
A biological sample cooling device with a cavity unit, cooling control unit, and circulating cooling unit that adjusts temperature gradients and uses liquid nitrogen with heated gas to maintain stable cooling, incorporating features like lifting and lowering members, heating elements, and a multifunctional cooling system for sample handling.
Enables intelligent temperature control with gentle gradients, preventing sample damage and ensuring efficient storage of multiple samples with adjustable temperature settings.
Smart Images

Figure 2026516441000001_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of biological sample storage, and particularly to a cooling device for biological samples and a multifunctional cooling system.
Background Art
[0002] Currently, the cooling of biological sample freezing storage tubes and freezing storage boxes does not achieve an automated cooling function. Biological samples usually need to maintain the activity of biological samples in an ultra-low temperature environment, and the storage temperatures are generally -80°C, -140°C, -196°C, etc. On the other hand, the freezing storage rate of biological samples plays an important role in the activity of biological samples. The conventional storage method directly places the freezing storage box in the relay box or relay tank inside the tank body, and a gentle cooling operation with a certain gradient has not been realized, and there is an easy risk of damage due to the rapid cooling of the temperature of biological samples.
[0003] Therefore, the inventor invented a device for gently cooling biological samples, and added that when the temperature of liquid nitrogen drops excessively, the gas in the cabin can be heated to rewarm the cooling environment, and a plurality of biological sample racks can be cooled and stored.
Summary of the Invention
Problems to be Solved by the Invention
[0004] This part aims to briefly explain some forms of embodiments of the present invention and introduce some preferred embodiments. In this part, as well as in the specification, abstract and title of the present application, in order to avoid the ambiguity of these purposes, some simplifications and omissions may be made, and these simplifications and omissions are not for the purpose of limiting the scope of the present invention.
Means for Solving the Problems
[0005] In view of the above or prior art problems, the present invention is proposed.
[0006] Accordingly, the present invention aims to provide a biological sample cooling device that can cool biological samples in a biological rack, can cool biological samples with a gentle gradient using a cooling control unit, and when the temperature of liquid nitrogen is detected to be excessively low by the circulating cooling unit, can draw in gas, heat the gas, send it into the circulation box, and use it in cooperation with the liquid nitrogen to raise the temperature of the liquid nitrogen, thereby slowly cooling the biological samples, and can store multiple sets of biological samples in the circulation box.
[0007] To solve the above problems, the present invention provides the following technical solution: a biological sample cooling device comprising a cavity unit, a cooling control unit, a circulating cooling unit, and a biological rack.
[0008] The cavity unit is provided with a temperature control unit and a circulating temperature control unit, the circulating temperature control unit is located to the side of the temperature control unit, the temperature control unit can independently cool the biological racks in a gradient, the interior of the circulating temperature control unit can accommodate multiple sets of biological racks, the circulating temperature control unit can provide adjustable temperature control for the multiple sets of biological racks inside it, and at least one set of temperature control unit and / or circulating temperature control unit is provided.
[0009] As one preferred embodiment of the biological sample cooling device of the present invention, the cooling control unit includes a cooling cylinder member and a lifting and lowering insertion / removal member.
[0010] A lifting and lowering member is provided above the cooling cylinder member. The lifting and lowering member can be driven to move the biological rack into the cooling cylinder member. Liquid nitrogen is placed inside the cooling cylinder member, and the cooling cylinder member can control the temperature of the liquid nitrogen. The lifting and lowering member can detect the temperature of the biological rack and the ambient temperature of the biological rack.
[0011] As one preferred embodiment of the biological sample cooling device of the present invention, the cooling cylinder member includes a cooling vacuum cylinder, a liquid nitrogen valve, and a liquid addition pipeline.
[0012] The cooling vacuum cylinder is connected to and fixed to the cavity unit, and a liquid nitrogen valve can control the liquid addition pipeline to place liquid nitrogen inside the cooling vacuum cylinder.
[0013] As one preferred embodiment of the biological sample cooling device of the present invention, the lifting and lowering loading / unloading member includes a support plate, a support sliding plate, a guide rail support plate, a screw, a lowering guide slider, a fixing block, a buffer spring, a temperature sensor, a sample temperature detection tube, a rack storage base, a first motor, and a slider guide rail.
[0014] A support sliding plate is provided on the side of the support plate, a guide rail support plate is connected to the side of the support sliding plate, a first motor support base is connected to the upper end side of the guide rail support plate, a first motor is mounted on the first motor support base, the first motor is connected vertically to the screw via a transmission shaft, the screw is connected to a fixed block and a descent guide slider, a slider guide rail is fixedly provided on the side of the guide rail support plate, the descent guide slider and fixed block slide against the slider guide rail, a buffer spring is connected to the lower end of the fixed block, a temperature sensor is connected to the lower end of the buffer spring, a sample temperature detection tube is provided at the lower end of the temperature sensor, a rack storage base is connected to the lower end of the guide rail support plate, a biological rack can be placed on the rack storage base, a chain is connected to the side of the support sliding plate, and the support sliding plate and the support plate slide against each other vertically.
[0015] As one preferred embodiment of the biological sample cooling device of the present invention, the circulating cooling unit includes a circulating cylinder member, an intake member, and a heating member.
[0016] The circulation cylinder member is connected to and fixed to the cavity unit, the lower end of the circulation cylinder member is connected to the heating member via a pipeline, the heating member is connected to the intake member, and the intake member is connected to the cavity unit.
[0017] As one preferred embodiment of the biological sample cooling device of the present invention, the intake member includes a fan, a mesh plate, and an intake tube.
[0018] A mesh plate is connected above the fan, and the fan is connected to the intake pipe.
[0019] In one preferred configuration of the biological sample cooling device of the present invention, the heating element includes a heating module and an air supply pipe.
[0020] The heating module is connected to the intake pipe, and the heating module is connected to the supply pipe.
[0021] In one preferred embodiment of the biological sample cooling device of the present invention, the circulation cylinder member includes a joining chamber, a nitrogen ejection tube, an ejection tube, a cooling guide tray, and a circulation cylinder.
[0022] The air supply pipe is connected to the junction chamber, which is located inside the circulation cylinder, the nitrogen ejection pipe is located around the junction chamber and is connected to the junction chamber, the blowpipe is located above the nitrogen ejection pipe, the blowpipe is connected to the junction chamber via a pipeline, multiple sets of blowpipes and nitrogen ejection pipes are provided circumferentially, the blowpipe has an upward-facing circular hole, a cooling guide tray is provided above the blowpipe, the cooling guide tray has mesh-like holes, a rack column is provided above the cooling guide tray, biological racks can be arranged inside the circulation cylinder by the rack column, and multiple sets of biological racks can be provided inside the circulation cylinder.
[0023] As one preferred configuration of the biological sample cooling device of the present invention, the nitrogen jet is connected to the liquid addition pipeline.
[0024] The beneficial effects of the biological sample cooling device of the present invention are as follows. The present invention can cool a single plate of biological samples by the cooling adjustment unit to have a gentle gradient, and can detect the temperature of liquid nitrogen by the circulating cooling unit. When the temperature is too low, the gas in the cavity unit is sucked into the heating module for heating to rewarm the liquid nitrogen, realizing intelligent temperature adjustment, and can co-regulate the temperature of multiple sets of biological samples stored in the circulating cooling unit.
[0025] During the use process, since it is necessary to frequently place the biological rack in the circulation cylinder, an additional rack gripping unit is provided. Since it is difficult to place an external biological rack in the operation chamber, a transfer tank joined to the cavity unit is provided. Therefore, the inventor designed a multifunctional cooling system.
[0026] To achieve the above problems, the present invention further provides the following technical solutions. It includes a biological sample cooling device, and further includes a conveying unit, a jacking unit, a holder unit, a lid opening unit, a rotary liquid adding unit, a rack gripping unit, a straw unit, a sample stocker, a code scanner, and a transfer tank.
[0027] The holder unit supports the conveying unit, the jacking unit and the cavity unit. The conveying unit can convey the transfer tank. The jacking unit can jack the transfer tank and join it with the cavity unit. The lid opening unit can open the upper lid of the transfer tank. The rotary liquid adding unit can add liquid to the transfer tank. The straw unit can suck excessive nitrogen gas. The rack gripping unit is used to grip the biological rack. The biological rack can be placed in the sample stocker. The code scanner can scan the label of the biological rack.
[0028] As a preferred embodiment of the multi-functional temperature reduction system of the present invention, the cavity unit includes an operation support plate and an operation chamber case. The operation chamber case is connected above the operation support plate, and an operation chamber is formed by the operation support plate and the operation chamber case. In the operation chamber, a lid opening unit, a rotary liquid adding unit, a rack gripping unit, a straw unit, a sample stocker, and a code scanner are provided.
[0029] As a preferred embodiment of the multi-functional temperature reduction system of the present invention, the holder unit includes a holder and a support base. The upper end of the holder is connected to the operation support plate, and the support base is provided at the side end of the holder.
[0030] As a preferred embodiment of the multi-functional temperature reduction system of the present invention, the conveying unit includes a conveying cart and a conveying guide rail.
[0031] The conveying guide rail is provided above the support base, and the conveying cart is slidably connected to the conveying guide rail.
[0032] As a preferred embodiment of the multi-functional temperature reduction system of the present invention, the jacking unit includes a jacking guide rail, a jacking motor, a jacking screw, a jacking slider, a jacking U-shaped plate, and a jacking plate.
[0033] The jacking guide rail is fixedly connected to the holder in the vertical direction. The jacking slider is cooperatively connected to the jacking screw. The upper end and the lower end of the jacking guide rail are used to support the jacking screw. The jacking motor rotates the jacking screw through a pulley. The jacking U-shaped plate is fixedly connected to the side surface of the jacking slider. The jacking plate is provided at the upper position above the center of the conveying cart. The transfer tank is provided on the upper end surface of the jacking plate. The jacking U-shaped plate can lift the jacking plate.
[0034] As one preferred solution for the multifunctional cooling system of the present invention, the lid opening unit includes a door cover plate, a door cover motor, and a door cover rotating shaft.
[0035] The door cover motor is connected to the door cover rotation shaft, the door cover plate is connected to the door cover rotation shaft, the door cover rotation shaft is supported by the door cover support base, and the door cover support base is connected to the operating support plate.
[0036] As one preferred solution for the multifunctional cooling system of the present invention, the rack gripping unit includes an X-axis slide rail, a Y-axis slide rail, a knob motor, a knob rotation axis, and a rack knob.
[0037] The Y-axis slide rail is connected to the inside of the operating chamber case, the Y-axis slide rails are arranged symmetrically, the two symmetrical sets of Y-axis slide rails are connected by the X-axis slide rail, the X-axis slide rail slides against the Y-axis slide rail, a knob motor is provided on one side of the X-axis slide rail, the knob motor is connected to the knob rotation shaft via a pulley, and a rack knob is connected below the knob rotation shaft.
[0038] As one preferred embodiment of the multifunctional cooling system of the present invention, the straw unit includes an electric cylinder, a straw motor, a liquid nitrogen cup, a straw screw, a straw, and a suction head.
[0039] The electric cylinder is mounted on one side of the X-axis slide rail away from the knob motor. The side of the electric cylinder is provided with a motor guide rail, a straw motor that slides against the motor guide rail, and a straw screw connected to the straw motor. A straw is connected below the straw motor, a liquid nitrogen cup is provided on the outside of the straw, and the lower end of the straw is connected to the suction head.
[0040] As one preferred solution to the multifunctional cooling system of the present invention, a sample stocker is provided on an operating support plate, a biological rack can be housed inside the sample stocker, a second door cover plate is provided above the sample stocker, and a second door cover plate motor drives the second door cover plate to open and close the sample stocker.
[0041] As one preferred solution for the multifunctional cooling system of the present invention, the rotary liquid addition unit includes a rotary liquid addition motor, a liquid addition cylinder, and a liquid addition tube.
[0042] A rotary liquid addition motor is connected to the liquid addition cylinder via a pulley, an additional liquid tube is connected to the liquid addition cylinder, the liquid addition cylinder is supported via a support shaft, and the support shaft is connected to the inner surface of the operating chamber case. [Effects of the Invention]
[0043] The beneficial effects of the multifunctional cooling system of the present invention are as follows: The present invention allows a transfer tank to be moved above a jacking unit by a transport unit, the jacking unit to drive the transfer tank upward and connect it to a cavity unit, and after connection, a lid opening unit can open the top lid of the transfer tank, and a rack gripping unit and a straw unit are used to grip a biological rack or a single tube of biological sample, thereby enabling the biological rack or single tube of biological sample to be placed in a cooling control unit or a circulating cooling unit to cool the biological sample. [Brief explanation of the drawing]
[0044] To more clearly explain the technical concepts of the embodiments of the present invention, the drawings that may be used in the description of the embodiments are briefly introduced below. As will be clear, the drawings in the following description are merely some embodiments of the present invention, and those skilled in the art can obtain other drawings based on these drawings without expending any creative effort. [Figure 1] This is a schematic diagram of a biological sample cooling system. [Figure 2] This is a schematic diagram of a concealed operation chamber case for a biological sample cooling device. [Figure 3] This is a three-dimensional schematic diagram of the temperature control unit and circulating temperature control unit of a biological sample cooling device. [Figure 4] This is a magnified view of section F1 of the biological sample cooling device. [Figure 5] This is a schematic diagram of the disassembled circulating cooling unit of a biological sample cooling device. [Figure 6] This is a magnified view of section F2 of the biological sample cooling device. [Figure 7] This is a three-dimensional schematic diagram of a multi-functional cooling system. [Figure 8] This is a schematic diagram of a multi-functional cooling system viewed from a different perspective. [Figure 9] This is a schematic diagram of a rotary liquid addition unit for a multi-functional cooling system. [Figure 10] This is a schematic diagram of the straw unit of a multi-functional cooling system. [Figure 11] This is a schematic diagram of the rack gripping unit of a multi-functional cooling system. [Figure 12] This is a schematic diagram of a jacking unit for a multi-functional cooling system. [Modes for carrying out the invention]
[0045] To further clarify the above-mentioned objectives, features, and advantages of the present invention, specific embodiments of the present invention will be described in detail below with reference to the drawings.
[0046] While the following description provides many specific details to fully understand the present invention, it is possible to carry out the invention in ways different from those described herein, and those skilled in the art can draw analogies without departing from the concept of the invention; therefore, the present invention is not limited to the specific embodiments disclosed below.
[0047] Next, the terms “one embodiment” or “example” as used herein mean a particular feature, structure or characteristic of at least one implementation that may be included in the present invention. “In one embodiment” appearing elsewhere in this specification does not refer to the same embodiment, nor is it a standalone or selective embodiment that is mutually exclusive with the other embodiments.
[0048] <Example 1> Referring to Figures 1 to 6, the first embodiment of the present invention provides a biological sample cooling device comprising a cavity unit 1, a cooling control unit 2, a circulating cooling unit 3, and a biological rack 15. The cavity unit 1 allows for the formation of a sealed operating chamber inside, the circulating cooling unit 3 allows for the gradient cooling of individual biological racks 15, multiple single-tube biological samples can be placed in the biological racks 15, the circulating cooling unit 3 can detect the temperature of liquid nitrogen, and if the temperature is excessively low, the gas in the cavity unit 1 is drawn into a heating module, heated, and remixed with the liquid nitrogen to raise the temperature of the liquid nitrogen and gradually cool the biological samples. This enables intelligent temperature control, and multiple sets of biological racks 15 can be stored in the circulating cooling unit 3, significantly improving operational efficiency.
[0049] Specifically, it includes a cavity unit 1, a temperature control unit 2, a circulating temperature control unit 3, and a biological rack 15.
[0050] The cavity unit 1 is provided with a temperature control unit 2 and a circulating temperature control unit 3. The circulating temperature control unit 3 is located to the side of the temperature control unit 2. The temperature control unit 2 can independently cool the biological racks 15 in a gradient manner. The interior of the circulating temperature control unit 3 can accommodate multiple sets of biological racks 15. The circulating temperature control unit 3 can provide adjustable temperature control for the multiple sets of biological racks 15 inside it. At least one set of temperature control unit 2 and / or circulating temperature control unit 3 is provided.
[0051] Preferably, multiple sets of circulating cooling units 3 may be provided, thereby allowing for the storage of more biological samples.
[0052] Furthermore, the cooling control unit 2 includes a cooling cylinder member 21 and a lifting / lowering extension member 22.
[0053] A lifting and lowering insertion / removal member 22 is provided above the cooling cylinder member 21. The lifting and lowering insertion / removal member 22 can be driven to move the biological rack 15 into the cooling cylinder member 21. Liquid nitrogen is placed inside the cooling cylinder member 21, and the cooling cylinder member 21 can control the temperature of the liquid nitrogen. The lifting and lowering insertion / removal member 22 can detect the temperature of the biological rack 15 and the ambient temperature of the biological rack 15.
[0054] Preferably, a notch is made in the operating support plate 111, the cooling cylinder member 21 is provided within the notch, and the lifting / lowering insertion / removal member 22 can be driven to raise and lower the biological rack 15.
[0055] Furthermore, the cooling cylinder member 21 includes a cooling vacuum cylinder 211, a liquid nitrogen valve 212, and a liquid addition pipeline 213.
[0056] The cooling vacuum cylinder 211 is connected to and fixed to the cavity unit 1, and the liquid nitrogen valve 212 can control the liquid addition pipeline 213 to place liquid nitrogen inside the cooling vacuum cylinder 211.
[0057] Preferably, the cooling vacuum cylinder 211 is fixed to the operating support plate 111, and liquid nitrogen can be introduced into the cooling vacuum cylinder 211 via the liquid addition pipeline 213.
[0058] Furthermore, the lifting and lowering member 22 includes a support plate 221, a support sliding plate 222, a guide rail support plate 223, a screw 224, a lowering guide slider 225, a fixing block 226, a buffer spring 227, a temperature sensor 228, a sample temperature detection tube 229, a rack storage base 230, a first motor 231, and a slider guide rail 232.
[0059] A support sliding plate 222 is provided on the side of the support plate 221, a guide rail support plate 223 is connected to the side of the support sliding plate 222, a first motor support base is fixedly connected to the upper end side of the guide rail support plate 223, a first motor 231 is mounted on the first motor support base, the first motor 231 is vertically connected to a screw 224 via a transmission shaft, the screw 224 is connected in cooperation with a descent guide slider 225, a fixed block 226 is fixedly connected to the descent guide slider 225, and a slider guide rail 232 is fixedly provided on the side of the guide rail support plate 223, and descent guide The slider 225 and the fixed block 226 are in sliding contact with the slider guide rail 232, a buffer spring 227 is connected to the lower end of the fixed block 226, a temperature sensor 228 is connected to the lower end of the buffer spring 227, a sample temperature detection tube 229 is provided at the lower end of the temperature sensor 228, a rack storage base 230 is connected to the lower end of the guide rail support plate 223, a biological rack 15 can be placed on the rack storage base 230, a chain is connected to the side of the support sliding plate 222, the chain can drive the support sliding plate 222 to move up and down, and the support sliding plate 222 and the support plate 221 are in sliding contact up and down.
[0060] Preferably, the support plate 221 is connected to and fixed inside the operating chamber case 112, and the support sliding plate 222 slides up and down along the rail on the side of the support plate 221.
[0061] The movement process of the lifting and lowering member 22 is as follows: By driving the chain with a motor, the support sliding plate 222 moves up and down along the rail on the side of the support plate 221, causing the support sliding plate 222 to move, which in turn causes the first motor 231 to move, and the rack storage base 230 fixed to the support sliding plate 222 also moves simultaneously, causing the biological rack 15 on the rack storage base 230 to move, and as it moves downward, the biological rack 15 enters the cooling vacuum cylinder 211, the first motor 231 rotates the screw 224, the screw 224 moves the fixed block 226 up and down, the fixed block 226 moves the temperature sensor 228 and the sample temperature detection tube 229, the cooling vacuum cylinder controls the temperature of the liquid nitrogen, the sample temperature detection tube 229 detects the temperature of the biological tubes in the biological rack 15, and the temperature sensor 228 detects the temperature of the liquid nitrogen.
[0062] When placing biological samples in the biological rack 15 into the cooling vacuum cylinder 211, the cooling vacuum cylinder 211 lowers the temperature of the biological samples by adjusting the temperature of the liquid nitrogen environment. First, the temperature of the biological samples is lowered from room temperature (20°C) to 4°C, then the sample temperature is lowered to -4°C at a rate of 1°C / min, the ambient temperature is lowered to -40°C at a rate of 20°C / min, the ambient temperature is lowered to -20°C at a rate of 15°C / min, the ambient temperature is lowered to -40°C at a rate of 1°C / min, and finally the ambient temperature is lowered to -90°C at a rate of 15°C / min, thereby ending the cooling process. The activity of the biological samples is ensured by cooling them in stages.
[0063] Furthermore, the circulating cooling unit 3 includes a circulating cylinder member 31, an intake member 33, and a heating member 35.
[0064] The circulation cylinder member 31 is connected to and fixed to the cavity unit 1, the lower end of the circulation cylinder member 31 is connected to the heating member 35 via a conduit, the heating member 35 is connected to the intake member 33, and the intake member 33 is connected to the cavity unit 1.
[0065] Preferably, the intake member 33 draws in the gas inside the cavity unit 1, heats it after passing it through the heating member 35, and then mixes the heated gas with the liquid nitrogen in the circulation cylinder member 31 to raise the temperature of the liquid nitrogen and avoid a rapid decrease in temperature.
[0066] Furthermore, the intake member 33 includes a fan 331, a mesh plate 332, and an intake pipe 333.
[0067] A mesh plate 332 is connected above the fan 331, and the fan 331 is connected to the intake pipe 333.
[0068] Preferably, the operating support plate 111 has holes for accommodating the mesh plate 332, and the mesh plate 332 can filter out relatively large foreign matter.
[0069] Furthermore, multiple sets of the circulating cooling unit 3 may be provided, allowing for the storage of more biological samples and enabling the biological samples to be cooled slowly and intelligently.
[0070] Furthermore, the heating element 35 includes a heating module 351 and an air supply pipe 352.
[0071] The heating module 351 is connected to the intake pipe 333, and the heating module 351 is connected to the supply pipe 352.
[0072] Preferably, the gas drawn into the intake pipe 333 is heated by the heating module 351 before being sent into the supply pipe 352.
[0073] Furthermore, the circulation cylinder member 31 includes a joining chamber 311, a nitrogen ejection pipe 312, an injection pipe 313, a cooling guide tray 314, and a circulation cylinder 315.
[0074] The air supply pipe 352 is connected to the junction chamber 311, which is located inside the circulation cylinder 315, the nitrogen ejection pipe 312 is located around the junction chamber 311 and is connected to the junction chamber 311, the jet pipe 313 is located above the nitrogen ejection pipe 312, the jet pipe 313 is connected to the junction chamber 311 via a pipeline, multiple sets of jet pipes 313 and nitrogen ejection pipes 312 are provided in the circumferential direction, the jet pipe 313 has an upward-facing circular hole, the cooling guide tray 314 is located above the jet pipe 313, the cooling guide tray 314 has mesh-like holes, the rack column is located above the cooling guide tray 314, the biological racks 15 can be arranged inside the circulation cylinder 315 by the rack column, and multiple sets of biological racks 15 can be provided inside the circulation cylinder 315.
[0075] Preferably, multiple sets of nitrogen ejection tubes 312 and ejection tubes 313 may be provided, the connecting chamber 311 may be fixedly connected to the air supply pipe 352, and the connecting chamber 311 may rotate around the air supply pipe 352. In this way, the nitrogen ejection tube 312 can be rotated, the ejection tube 313 can also be rotated, and circular holes are provided in the nitrogen ejection tube 312 and the ejection tube 313, making it easier for nitrogen gas and heated gas to be ejected more uniformly upwards.
[0076] Furthermore, the nitrogen injection pipe 312 is connected to the liquid injection pipeline 213.
[0077] During use, the cooling process by the cooling control unit 2 is as follows: By driving the chain with a motor, the support sliding plate 222 moves up and down along the rail on the side of the support plate 221, causing the support sliding plate 222 to move, which in turn drives the first motor 231, and the rack storage base 230 fixed to the support sliding plate 222 also moves simultaneously, causing the biological rack 15 on the rack storage base 230 to move, and as it moves downward, the biological rack 15 enters the cooling vacuum cylinder 211, the first motor 231 rotates the screw 224, the screw 224 moves the fixed block 226 up and down, the fixed block 226 moves the temperature sensor 228 and the sample temperature detection tube 229, the cooling vacuum cylinder controls the temperature of the liquid nitrogen, the sample temperature detection tube 229 detects the temperature of the biological tubes in the biological rack 15, and the temperature sensor 228 detects the temperature of the liquid nitrogen.
[0078] The cooling operation by the circulating cooling unit 3 is as follows: When the temperature of the liquid nitrogen is detected to be excessively low, the fan 331 draws in the gas inside the cavity unit 1 and enters the heating module 351 via the intake pipe 333. The heated gas then enters the circulation cylinder 315 through the supply pipe 352 and the junction chamber 311. The heated gas is ejected via the nozzle pipe 313 and mixes with the liquid nitrogen ejected from the nitrogen ejection pipe 312. The nozzle pipe 313 also heats the cooling guide tray 314 above, where multiple sets of biological racks 15 are stored. This allows for heating of the liquid nitrogen environment, enabling adjustable and intelligent cooling and ensuring that biological samples are cooled gradually.
[0079] As described above, the present invention allows a single-plate biological sample to be cooled with a gentle gradient by the cooling control unit 2, and the temperature of the liquid nitrogen and the biological sample can be detected, thus avoiding the sample losing its activity due to rapid cooling by the liquid nitrogen. The circulating cooling unit 3 can detect the temperature of the liquid nitrogen, and if the temperature is excessively low, the gas in the cavity unit 1 is drawn into the heating module and heated to restore the temperature of the liquid nitrogen, thereby achieving intelligent temperature control, and multiple sets of biological samples can be stored in the circulating cooling unit 3 and collectively temperature-controlled.
[0080] <Example 2> Referring to Figures 7 to 12, a second embodiment of the present invention, based on Embodiment 1, further includes a multifunctional cooling system, the multifunctional cooling system includes a transport unit 4, a jacking unit 5, a holder unit 6, a lid opening unit 7, a rotary liquid addition unit 8, a rack gripping unit 9, a straw unit 10, a sample stocker 11, a code scanner 12, and a transfer tank 13, wherein the transport unit 4 allows the transfer tank 13 to be transported, the jacking unit 5 allows the transfer tank 13 to be jacked and connected to the cavity unit 1, the lid opening unit 7 allows the top lid of the transfer tank 13 to be opened, and the rotary liquid addition unit By providing the 8, liquid can be added to the transfer tank 13 and to the sample stocker 11. By providing the code scanner 12, single-tube biological samples or entire biological samples can be scanned and registered. By providing the rack gripping unit 9 and the straw unit 10, single-tube biological samples or entire biological samples can be gripped. The rack gripping unit 9 and the straw unit 10 can grip single-tube samples or entire biological samples in the transfer tank 13 and temporarily place them in the sample stocker 11. The rack gripping unit 9 can place the biological rack 15 on the rack storage stand 230 or inside the circulation cylinder 315.
[0081] Specifically, it includes a transport unit 4, a jacking unit 5, a holder unit 6, a lid opening unit 7, a rotary liquid addition unit 8, a rack gripping unit 9, a straw unit 10, a sample stocker 11, a code scanner 12, and a transfer tank 13.
[0082] The holder unit 6 supports the transport unit 4, the jacking unit 5, and the cavity unit 1. The transport unit 4 can transport the transport tank 13, the jacking unit 5 can jack the transport tank 13 and connect it to the cavity unit 1, the lid opening unit 7 can open the top lid of the transport tank 13, the rotary liquid addition unit 8 can add liquid to the transport tank 13, the straw unit 10 can suck up excess nitrogen gas, the rack gripping unit 9 is used to grip the biological rack 15 and place the biological rack 15 in the sample stocker 11, and the code scanner 12 can scan the labels on the biological rack 15.
[0083] Furthermore, the cavity unit 1 includes an operating support plate 111 and an operating chamber case 112, the operating chamber case 112 being connected above the operating support plate 111, and the operating support plate 111 and the operating chamber case 112 forming a single sealed operating chamber, the operating chamber being equipped with a lid opening unit 7, a rotary liquid addition unit 8, a rack gripping unit 9, a straw unit 10, a sample stocker 11, and a code scanner 12.
[0084] Preferably, an observation window is provided in the operating chamber case 112, allowing the internal state to be observed through the observation window.
[0085] Furthermore, the holder unit 6 includes a holder 61 and a support base 62. The upper end of the holder 61 is fixedly connected to the operating support plate 111, and the support base 62 is provided at the side end of the holder 61. The support base 62 is fixedly connected to the holder 61.
[0086] Furthermore, the transport unit 4 includes a transport vehicle 41 and a transport guide rail 42.
[0087] The transport guide rail 42 is installed above the support base 62, and the transport vehicle 41 slides against the transport guide rail 42.
[0088] Preferably, the transport guide rail 42 is fixedly connected to the support base 62.
[0089] Furthermore, the jacking unit 5 includes a jacking guide rail 51, a jacking motor 52, a jacking screw 53, a jacking slider 54, a jacking U-shaped plate 55, and a jacking plate 56.
[0090] The jacking guide rail 51 is fixed vertically to the holder 61, the jacking slider 54 is connected in cooperation with the jacking screw 53, the upper and lower ends of the jacking guide rail 51 have protrusions to support the jacking screw 53, the jacking motor 52 rotates the jacking screw 53 via a pulley, the jacking U-shaped plate 55 is fixedly connected to the side of the jacking slider 54, the jacking plate 56 is located in the upper central position of the transport vehicle 41, the transport tank 13 is located on the upper end surface of the jacking plate 56, and the jacking U-shaped plate 55 can raise and lower the jacking plate 56.
[0091] Preferably, the upper part of the jacking U-shaped plate 55 has a top claw, and the jacking plate 56 is provided with an engaging portion so that the top claw can be fitted into the engaging portion.
[0092] Preferably, the jacking motor 52 is driven via a pulley to rotate the jacking screw 53, and as the jacking screw 53 rotates, the jacking slider 54 moves vertically along the jacking guide rail 51, and as the jacking slider 54 rises, the top claw of the jacking U-shaped plate 55 rises, and after the top claw engages with the engaging portion of the jacking plate 56, the jacking plate 56 is raised, thereby raising the transfer tank 13 on the jacking plate 56 and fitting the transfer tank 13 into the operating support plate 111.
[0093] Furthermore, the lid opening unit 7 includes a door cover plate 71, a door cover motor 72, and a door cover rotating shaft 73.
[0094] The door cover motor 72 is connected to the door cover rotation shaft 73, the door cover plate 71 is connected to the door cover rotation shaft 73, the door cover rotation shaft 73 is supported by the door cover support base, and the door cover support base is connected to the operating support plate 111.
[0095] Preferably, the top lid of the transfer tank 13 is made of a magnetic material, and the door cover plate 71 may also be made of a magnetic material, thereby allowing the top lid of the transfer tank 13 to be opened by other means.
[0096] Preferably, the door cover motor 72 drives the door cover rotation shaft 73, and the door cover plate 71 opens the top lid of the transfer tank 13. The door cover plate 71 may also cover the notch in the operating support plate 111 that accommodates the transfer tank 13, in order to maintain the sealing of the cavity when the transfer tank 13 is not present.
[0097] Furthermore, the rack gripping unit 9 includes an X-axis slide rail 911, a Y-axis slide rail 912, a knob motor 913, a knob rotation shaft 914, and a rack knob 915.
[0098] The Y-axis slide rail 912 is connected to the inside of the operating chamber case 112, the Y-axis slide rails 912 are arranged symmetrically, the two symmetrical sets of Y-axis slide rails 912 are connected by the X-axis slide rail 911, the X-axis slide rail 911 slides against the Y-axis slide rail 912, a knob motor 913 is provided on one side of the X-axis slide rail 911, the knob motor 913 is connected to the knob rotation shaft 914 via a pulley, and a rack knob 915 is connected below the knob rotation shaft 914.
[0099] Preferably, the rack handle 915 can move along the X-axis slide rail 911, and the X-axis slide rail 911 can slide along the Y-axis slide rail 912. The rack handle 915 can grip the biological rack 15.
[0100] Preferably, the rack knob 915 can move up and down on the Z-axis, the rotating shaft holder and motor holder can move up and down by a chain, and the motor holder can slide up and down on the X-axis slide rail, thereby raising and lowering the rack knob 915. Alternatively, other prior art can be used as long as the up and down movement of the rack knob 915 on the Z-axis can be achieved.
[0101] Preferably, the rack handle 915 can move in the X, Y, and Z axes. The rack handle 915 can grip the biological rack 15.
[0102] Furthermore, the straw unit 10 includes an electric cylinder, a straw motor 102, a liquid nitrogen cup 104, a straw screw 105, a straw 106, and a suction head 107.
[0103] The electric cylinder is provided on one side of the X-axis slide rail 911 away from the knob motor 913. The side of the electric cylinder is provided with a motor guide rail, a straw motor 102 that slides against the motor guide rail, and a straw screw 105 connected to the straw motor 102. A straw 106 is connected below the straw motor 102, a liquid nitrogen cup 104 is provided on the outside of the straw 106, and the lower end of the straw 106 is connected to a suction head 107.
[0104] Preferably, the straw 106 and suction head 107 are configured such that the straw motor 102 drives the straw screw 105 to rotate, the straw motor 102 moves up and down along a motor guide rail, the liquid nitrogen cup 104 can cool the straw 106, the suction head 107 can suck up a single-tube sample, or an electric cylinder may be used to move the straw motor 102 and straw 106 up and down, or other prior art may be used as long as the straw 106 can perform an up and down movement.
[0105] Furthermore, the sample stocker 11 is mounted on the operation support plate 111, and the biological rack 15 can be stored inside the sample stocker 11. A second door cover plate is provided above the sample stocker 11, and the second door cover plate motor drives the second door cover plate to open and close the sample stocker 11.
[0106] Preferably, the bottom of the sample stocker 11 is connected to a liquid nitrogen valve 212 via a conduit, allowing liquid to be added to the sample stocker 11. A biological rack 15 can be temporarily placed inside the sample stocker 11, and a second door cover plate allows the sample stocker 11 to be opened and closed.
[0107] Furthermore, the rotary liquid addition unit 8 includes a rotary liquid addition motor 81, a liquid addition cylinder 82, and a liquid addition tube 83.
[0108] A rotary liquid addition motor 81 is connected to a liquid addition cylinder 82 via a pulley, a liquid addition pipe 83 is connected to the liquid addition cylinder 82, the liquid addition cylinder 82 is supported by a support shaft, and the support shaft is connected to the inner surface of the operating chamber case 112.
[0109] Preferably, the rotary liquid addition motor 81 is driven via a pulley to rotate the liquid addition cylinder 82, and the liquid addition cylinder 82 is driven to rotate the liquid replenishment pipe 83. By rotating, the liquid replenishment pipe 83 can add liquid to the transfer tank 13 and the sample stocker 11, respectively.
[0110] When in use, the transfer tank 13 is placed on the transport vehicle 41, which moves along the transport guide rail 42 above the jacking U-shaped plate 55. Next, the jacking motor 52 is driven via a pulley to rotate the jacking screw 53. As the jacking screw 53 rotates, the jacking slider 54 moves vertically along the jacking guide rail 51. As the jacking slider 54 rises, it raises the top claw on the jacking U-shaped plate 55. After the top claw engages with the engagement portion on the jacking plate 56, the jacking plate 56 is raised, thereby raising the transfer tank 13 on the jacking plate 56, and the transfer tank 13 cooperates with the operating support plate 111. Next, the door cover motor 72 drives the door cover rotation shaft 73, the door cover plate 71 opens the top lid of the transfer tank 13, the rotary liquid addition motor 81 rotates the liquid addition cylinder 82 via a pulley, the liquid addition cylinder 82 rotates the replenishment tube 83, and by rotating, the replenishment tube 83 can add or replenish liquid to the transfer tank 13 and the sample stocker 11, respectively. Subsequently, the rack handle 915 moves along the X, Y, and Z axes according to the system's command to sequentially place the biological racks 15 in the transfer tank 13 into the sample stocker 11 for standby, or uses the suction head 107 to grasp a single pipe and place it in the biological rack 15, or the rack handle 915 scans the biological rack 15 after grasping it and then places the biological rack 15 in the circulation cylinder 315 or the rack storage stand 230 for storage and cooling.
[0111] As described above, the present invention allows the transport unit 4 to move the transport tank 13 above the jacking unit 5, the jacking unit 5 to drive the transport tank 13 up and connect it with the cavity unit 1, and after connection, the lid opening unit 7 can open the top lid of the transport tank 13, and the rack gripping unit 9 and straw unit 10 are used to grip a biological rack or a single tube of biological sample, thereby placing the biological rack or single tube of biological sample in the cooling control unit 2 or the circulating cooling unit 3, thereby enabling the biological sample to be cooled.
[0112] It should be noted that the structures and arrangements of the present invention shown in several different exemplary embodiments are merely illustrative. While this disclosure only details a few embodiments, a person skilled in the art will understand that various modifications are possible (e.g., changes in the dimensions, scale, structure, shape, proportions, and parameters of various elements (e.g., temperature, pressure, etc.), mounting and distribution, use of materials, color, and orientation, etc.) without substantially departing from the novel teachings and merits of the subject described herein. For example, an element shown as a whole mold may consist of multiple parts or elements, the positions of the elements may be reversed, or otherwise modified. The properties, number, or position of discrete elements may be changed or altered. Thus, all such modifications are intended to fall within the scope of the invention. Any process, method step order, or sequence may be changed or rearranged based on alternative embodiments. In the claims, all "apparatus + function" clauses are intended to cover structures that perform the function described herein, and are equivalent configurations as well as equivalent configurations. Without departing from the scope of the present invention, other substitutions, modifications, changes, and omissions can be made to the design, operation, and arrangement of exemplary embodiments. Accordingly, the present invention is not limited to any particular embodiment and can be expanded to include many variations within the scope of the claims.
[0113] In order to provide a concise description of exemplary implementations, it is not necessary to describe all features of actual implementations (i.e., features that are not relevant to a currently conceivable preferred mode of carrying out the present invention, or features that are not relevant to realizing the present invention).
[0114] It should be understood that in the development process of any actual embodiment, for example, in any process or design item, many specific embodiments can be determined. Although such development efforts are complex and time-consuming, to those skilled in the art, such development efforts do not require excessive experimentation and have become routine tasks in design, manufacturing, and production.
[0115] The above embodiments are used merely to illustrate the technical concept of the present invention and are not restrictive. While the present invention has been described in detail with reference to preferred embodiments, it is possible to modify or substitute the technical concept of the present invention without departing from the spirit and scope of the technical concept, as will be understood by those skilled in the art, and such modifications and substitutions are all included within the scope of the claims. [Explanation of symbols]
[0116] 1 Cavity Unit 2. Temperature control unit 3. Circulating cooling unit 15 Biological Rack 21 Cooling cylinder parts 22 Lifting and lowering mechanism 211 Cooling vacuum tube 212 Liquid Nitrogen Valve 213 Liquid addition line 221 Support plate 222 Support sliding plate 223 Guide rail support plate 224 Screw 225 Descent Guide Slider 226 Fixed Blocks 227 Shock absorber spring 228 Temperature Sensor 229 Sample temperature detection tube 230 Rack Storage Stand 231 First motor 232 Slider Guide Rail 31 Circulation cylinder member 33 Intake component 35 Heating element 331 Fans 332 Mesh Plate 333 Intake pipe 351 Heating Module 352 Air supply pipe 311 Junction room 312 Nitrogen nozzle 313 Fuel nozzle 314 Cooling guide tray 315 Circulation tube 4. Transport Unit 5 Jacking Units 6 Holder Units 7. Lid opening unit 8 Rotary Liquid Addition Unit 9. Rack gripping unit 10 Straw Units 11 Sample Stocker 12 Code Scanners 13 Transfer Tank 111 Operation support plate 112 Operating Chamber Case 61 Holder 62 Support stand 41 Transport vehicle 42 Transport guide rails 51 Jacking guide rail 52 Jacking motor 53 Jacking Screw 54 Jacking Slider 55 Jacking U-shaped plate 56 Jacking board 71 Door cover plate 72 Door cover motor 73 Door cover rotation axis 911 X-axis slide rail 912 Y-axis slide rail 913 Knob Motor 914 Knob Rotation Axis 915 Rack knob 102 Straw Motor 104 Liquid Nitrogen Cups 105 Straw Screw 106 Straws 107 Suction Head 81 Rotary liquid-adding motor 82 Liquid addition tube 83 Fluid replacement tube
Claims
1. A biological sample cooling device comprising a cavity unit, a cooling control unit, a circulating cooling unit, and a biological rack, A biological sample cooling device characterized in that the cavity unit is provided with a cooling control unit and a circulating cooling unit, the circulating cooling unit is provided to the side of the cooling control unit, the cooling control unit can independently cool biological racks in a gradient, the interior of the circulating cooling unit can accommodate multiple sets of biological racks, the circulating cooling unit can perform adjustable temperature control for the multiple sets of biological racks inside it, and at least one set of the cooling control unit and / or the circulating cooling unit is provided.
2. The aforementioned temperature control unit includes a temperature cooling cylinder member and a lifting / lowering extension / retraction member. A biological sample cooling device according to claim 1, characterized in that a lifting and lowering insertion / removal member is provided above the cooling cylinder member, the lifting and lowering insertion / removal member can drive the biological rack into the cooling cylinder member, liquid nitrogen is placed inside the cooling cylinder member, the cooling cylinder member can control the temperature of the liquid nitrogen, and the lifting and lowering insertion / removal member can detect the temperature of the biological rack and the ambient temperature of the biological rack.
3. The cooling cylinder member includes a cooling vacuum cylinder, a liquid nitrogen valve, and a liquid addition pipeline. The cooling device for biological samples according to claim 2, characterized in that the cooling vacuum cylinder is connected to and fixed to the cavity unit, and the liquid nitrogen valve can control the liquid addition pipeline to place liquid nitrogen inside the cooling vacuum cylinder.
4. The lifting and lowering member includes a support plate, a support sliding plate, a guide rail support plate, a screw, a lowering guide slider, a fixing block, a buffer spring, a temperature sensor, a sample temperature detection tube, a rack storage base, a first motor, and a slider guide rail. A support sliding plate is provided on the side of the support plate, a guide rail support plate is connected to the side of the support sliding plate, a first motor support base is connected to the upper end side of the guide rail support plate, a first motor is mounted on the first motor support base, the first motor is connected vertically to the screw via a transmission shaft, the screw is connected to the fixed block and the lowering guide slider, a slider guide rail is fixedly provided on the side of the guide rail support plate, the lowering guide slider and the fixed block are in sliding contact with the slider guide rail, a buffer spring is connected to the lower end of the fixed block, a temperature sensor is connected to the lower end of the buffer spring, a sample temperature detection tube is provided at the lower end of the temperature sensor, a rack storage base is connected to the lower end of the guide rail support plate, a biological rack can be placed on the rack storage base, a chain is connected to the side of the support sliding plate, and the support sliding plate is in vertical sliding contact with the support plate.
5. The aforementioned circulating cooling unit includes a circulating cylinder member, an intake member, and a heating member. The cooling device for biological samples according to claim 1, characterized in that the circulation cylinder member is connected to and fixed to the cavity unit, the lower end of the circulation cylinder member is connected to the heating member via a pipe, the heating member is connected to the intake member, and the intake member is connected to the cavity unit.
6. The intake member includes a fan, a mesh plate, and an intake pipe. The biological sample cooling device according to claim 5, characterized in that a mesh plate is connected above the fan and the fan is in communication with the intake pipe.
7. The heating element includes a heating module and an air supply pipe. The cooling device for biological samples according to claim 6, characterized in that the heating module is connected to the intake pipe and the heating module is connected to the supply pipe.
8. The circulation cylinder member includes a joining chamber, a nitrogen ejection pipe, an ejection pipe, a cooling guide tray, and a circulation cylinder. The biological sample cooling device according to claim 7, characterized in that the air supply pipe is connected to the joining chamber, the joining chamber is provided in the circulation cylinder, the nitrogen ejection pipe is provided around the joining chamber and is connected to the joining chamber, the blower pipe is provided above the nitrogen ejection pipe, the blower pipe is connected to the joining chamber via a pipeline, multiple sets of the blower pipe and the nitrogen ejection pipe are provided in the circumferential direction, the blower pipe has a circular hole opening upward, a cooling guide tray is provided above the blower pipe, the cooling guide tray has mesh-like holes, a rack column is provided above the cooling guide tray, the biological rack can be arranged in the circulation cylinder by the rack column, and multiple sets of biological racks can be provided in the circulation cylinder.
9. The biological sample cooling device according to claim 8, characterized in that the nitrogen jet tube is connected to a liquid addition pipeline.
10. A multifunctional cooling system comprising a biological sample cooling device according to any one of claims 1 to 9, comprising a transport unit, a jacking unit, a holder unit, a lid opening unit, a rotary liquid addition unit, a rack gripping unit, a straw unit, a sample stocker, a code scanner, and a transfer tank, A multifunctional cooling system characterized in that the holder unit supports the transport unit, the jacking unit and the cavity unit, the transport unit can transport the transport tank, the jacking unit can jack the transport tank and connect it to the cavity unit, the lid opening unit can open the top lid of the transport tank, the rotary liquid adding unit can add liquid to the transport tank, the straw unit can suck up excess nitrogen gas, the rack gripping unit is used to grip the biological rack and can place the biological rack in the sample stocker, and the code scanner can scan the labels on the biological rack.
11. The multifunctional cooling system according to claim 10, wherein the cavity unit includes an operating support plate and an operating chamber case, the operating chamber case is connected above the operating support plate, the operating support plate and the operating chamber case form a single operating chamber, and the operating chamber is provided with a lid opening unit, a rotary liquid addition unit, a rack gripping unit, a straw unit, a sample stocker and a code scanner.
12. The multifunctional cooling system according to claim 11, wherein the holder unit includes a holder and a support base, the upper end of the holder is connected to the operating support plate, and the support base is provided at the side end of the holder.
13. The transport unit includes a transport vehicle and a transport guide rail. The multifunctional cooling system according to claim 12, characterized in that the transport guide rail is provided above the support base and the transport vehicle is in sliding contact with the transport guide rail.
14. The jacking unit includes a jacking guide rail, a jacking motor, a jacking screw, a jacking slider, a jacking U-shaped plate, and a jacking plate. The multifunctional cooling system according to claim 13, characterized in that the jacking guide rail is fixedly connected to the holder in the vertical direction, the jacking slider is connected in cooperation with the jacking screw, the upper and lower ends of the jacking guide rail have protrusions for supporting the jacking screw, the jacking motor rotates the jacking screw via a pulley, a jacking U-shaped plate is fixedly connected to the side of the jacking slider, the jacking plate is provided at an upper position in the center of the transport vehicle, the transport tank is provided on the upper end surface of the jacking plate, and the jacking U-shaped plate can raise and lower the jacking plate.
15. The aforementioned lid opening unit includes a door cover plate, a door cover motor, and a door cover rotating shaft. The multifunctional cooling system according to claim 14, characterized in that the door cover motor is connected to the door cover rotation shaft, the door cover plate is connected to the door cover rotation shaft, the door cover rotation shaft is supported by a door cover support base, and the door cover support base is connected to the operation support plate.
16. The rack gripping unit includes an X-axis slide rail, a Y-axis slide rail, a knob motor, a knob rotation shaft, and a rack knob. The multifunctional cooling system according to claim 15, characterized in that the Y-axis slide rail is connected to the inside of the operating chamber case, the Y-axis slide rail is provided symmetrically, two symmetrical sets of the Y-axis slide rail are connected by an X-axis slide rail, the X-axis slide rail slides against the Y-axis slide rail, a knob motor is provided on one side of the X-axis slide rail, the knob motor is connected to the knob rotation shaft via a pulley, and a rack knob is connected below the knob rotation shaft.
17. The straw unit includes an electric cylinder, a straw motor, a liquid nitrogen cup, a straw screw, a straw, and a suction head. The multifunctional cooling system according to claim 16, wherein the electric cylinder is provided on one side of the X-axis slide rail away from the knob motor, the side surface of the electric cylinder is provided with a motor guide rail, a straw motor that slides against the motor guide rail, and a straw screw connected to the straw motor, a straw is connected below the straw motor, a liquid nitrogen cup is provided on the outside of the straw, and the lower end of the straw is connected to the suction head.
18. The multifunctional cooling system according to claim 17, characterized in that the sample stocker is provided on the operation support plate, a biological rack can be stored inside the sample stocker, a second door cover plate is provided above the sample stocker, and a second door cover plate motor drives the second door cover plate to open and close the sample stocker.
19. The rotary liquid addition unit includes a rotary liquid addition motor, a liquid addition cylinder, and a liquid addition tube. The multifunctional cooling system according to claim 18, characterized in that the rotary liquid addition motor is connected to the liquid addition cylinder via a pulley, the liquid addition tube is connected to the liquid addition cylinder, the liquid addition cylinder is supported by a support shaft, and the support shaft is connected to the inner surface of the operation chamber case.