Chaga-related preparations, compounds, compositions, and methods of manufacturing and using the same.

JP2026520079APending Publication Date: 2026-06-22ジェロシンス ラボラトリーズインコーポレイテッド

Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
ジェロシンス ラボラトリーズインコーポレイテッド
Filing Date
2024-05-01
Publication Date
2026-06-22

AI Technical Summary

Technical Problem

Current cancer treatments, particularly those involving mushrooms, face challenges such as low bioavailability of key compounds like betulinic acid, leading to limited therapeutic effectiveness and potential side effects, and there is a need for more effective and less toxic therapeutic approaches for both human and animal cancers.

Method used

A functional food or medical formulation is developed by combining a reduced Chaga product and extract with esterification mixtures containing proline, fructose, fatty acids, and Manuka honey, which enhances the bioavailability of betulinic acid and other compounds, forming a pharmaceutical composition for cancer treatment.

Benefits of technology

The formulation demonstrates improved cytotoxic effects on cancer cells, inducing apoptosis and inhibiting proliferation, with enhanced bioavailability addressing the limitations of betulinic acid, offering a potentially safer and more effective treatment option.

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Abstract

Medical preparations and functional food preparations, compounds, and pharmaceutical compositions based on Chaga, as well as methods for their manufacture. When administered to humans or animals, the preparations, compounds, and pharmaceutical compositions are useful for treating diseases such as cancer. Functional food preparations include a reduced product of Chaga formed in a reducing solvent and an extract of Chaga formed in an extracting solvent. The reduced product and the extract are mixed or combined according to methods known to those skilled in the art to form functional food preparations. The medical formulations are reaction products produced by preparing a reduced Chaga product in a pressurized reducing solvent, preparing a Chaga extract in an extraction solvent, mixing or combining the reduced Chaga product with the Chaga extract, mixing or combining the Chaga formulation with an esterification mixture containing proline, fructose, and fatty acids for generating esterification compounds and a source of sugar esters that can be emulsified in otherwise immiscible liquid compounds, or with a predetermined amount of Manuka honey sufficient to bring about esterification and promote emulsification, at a temperature that can induce a reaction between the components of Chaga and the esterification mixture or Manuka honey, and combining the heterogeneous mixture with medium-chain triglyceride oil.
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