Fluid chip and cell encapsulation system
The fluid tip with non-coaxial inlets and three-dimensional channels addresses the instability of coaxial jets in fluid chips, achieving stable flow symmetry and reduced pressure drops, facilitating high-throughput cell encapsulation systems.
Patent Information
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- TREEFROG THERAPEUTICS
- Filing Date
- 2024-04-19
- Publication Date
- 2026-06-23
AI Technical Summary
Existing fluid chips face challenges in producing stable coaxial jets, particularly in air, due to limitations in manufacturing techniques that result in unstable flow dynamics and high pressure drops, especially when dealing with viscous fluids, and require complex mounting steps for coaxial capillaries.
A fluid tip design with a main inlet and non-coaxial secondary inlets, featuring three-dimensional channels that merge into a circular injection duct, ensuring homogeneous flow distribution and stability by implementing secondary channels with equal hydraulic resistance, allowing for compact dimensions along the Z-axis without coaxial inflow injection.
The design stabilizes coaxial jets, enhances flow symmetry, and reduces pressure drops, enabling high-throughput cell encapsulation systems with improved stability and efficiency, particularly suitable for viscous fluids and three-dimensional culture systems.
Smart Images
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