Use of compounds as whitening compositions and depigmentation agents

Abstract

The present invention relates to a whitening composition comprising a whitening effective amount of a compound of formula (I), or a tautomer, stereoisomer, hydrate, solvate, salt, or polymorph thereof, wherein R 1 、R 2 、R 3 、R 4 、R 5 、R 6 、R 7 、m and n are as defined in the specification and claims. The present invention also relates to a compound of formula (I2) or a tautomer, stereoisomer, hydrate, solvate, salt, or polymorph thereof, wherein R 1 、R 2 、R 3 、R 4 、R 5 、R 6 、and R 7 are as defined in the specification and claims. The present invention also relates to the use of at least one compound of formula (I) or any subgroup thereof, or a mixture thereof, as a depigmenting agent. The present invention also relates to the use of at least one compound of formula (I) or any subgroup thereof, or the use of a whitening composition, for preventing and / or reducing pigmentation of normal skin. The present invention also relates to the use of at least one compound, or the use of a whitening composition according to the first aspect, for reducing the amount of melanin in melanocytes, for reducing melanin synthesis, for impairing melanin transport, and / or for impairing the distribution of melanin in the upper basal layer. JPEG2026520910000038.jpg3191

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