Signal sensing device

Abstract

This solves the problem that signals transmitted by conventional signal sensing devices are susceptible to environmental interference. [Solution] The signal sensing device includes a main body 1 and two signal sensing elements 2, the two signal sensing elements are installed inside the main body, an insulating layer I is sandwiched between the two signal sensing elements, the two signal sensing elements each have a signal transmission segment 2a and a signal sensing segment 2b electrically connected to each other, the signal transmission segments are parallel planar antennas and have a meandering line type antenna shape, in the plane where the signal transmission segments are parallel to each other, the vertical projections of the antenna shapes do not completely overlap, and when a part of the main body forms an enclosing part to enclose the object to be measured, a part or all of the signal sensing segments are located in the enclosing part. According to the present invention, the quality of signal transmission can be improved.

Description

[Technical field]

[0001] FIELD OF THEINVENTION This invention relates to sensing technology, and more particularly to signal sensing devices. [Background technology]

[0002] In conventional methods of surrounding the object to be measured and measuring related signals, particularly when the signal sensing device is directly incorporated into the living body to measure biological signals without external wiring, the sensed signal cannot be efficiently transmitted to the outside due to interference from the measurement environment in which the signal detection device exists, and the external analytical device cannot obtain the corresponding transmitted signal, making it impossible to know the physiological condition of the living body in real time. [Prior art documents] [Patent documents]

[0003] [Patent Document 1] US Publication No. 2015 / 0073240 Summary of the Invention [Problem to be solved by the invention]

[0004] Based on the above-mentioned problems, there is a need to further improve conventional signal sensing devices.

[0005] SUMMARY OF THE PRESENT DISCLOSURE In order to solve the above problems, a first object of the present invention is to provide a signal sensing device capable of improving the quality of signal transmission.

[0006] A second object of the present invention is to provide a signal sensing device that can be placed inside a living organism and that can be degraded over time and absorbed by the organism. [Means for solving the problem]

[0007] The terms of direction or approximate terms used throughout the specification of the present invention, such as "front," "rear," "left," "right," "top," "bottom," "inside," "outside," "side," etc., mainly indicate directions in the accompanying drawings, and each term of direction or approximate terms is intended to aid in the explanation and understanding of each embodiment of the present invention, and is not intended to limit the present invention.

[0008] The use of the numerals "one" or "one piece" in the description of parts and members throughout the specification of the present invention is merely for convenience and to provide the ordinary meaning within the scope of the present invention, and should be read as including one or at least one in the present invention, and the singular concept also includes plural situations unless clearly otherwise indicated.

[0009] The definitions of the dimensional standards described throughout the present invention are based on FIG. 1 of the present invention, and the "length" described is the length of the head or extension of the body (e.g., the symbol L H Or L E ), i.e. along the extension of the reference axis Y shown in FIG. 1. The "width" referred to is the width of the head or extension of the body (e.g., the width represented by the symbol W H or W E ), i.e. along the extension of the reference axis X shown in FIG. 1. The "thickness" mentioned (which can also be expressed as height) is the thickness of the head or extension of the body (e.g., the thickness indicated by the symbol T H or T E ), i.e., along the extension direction of the reference axis Z shown in FIG. 1. Furthermore, the dimensional adjustment of all dimensional standards described in the present invention may be adjusted at intervals of 0.1 μm. Furthermore, the frequency adjustment of the "operating frequency" described throughout the present invention may be adjusted at intervals of 1 MHz. Furthermore, all specific numerical values ​​described in the present invention may have a tolerance range of plus or minus 10%.

[0010] The signal sensing device of the present invention includes a main body and two signal sensing elements, the two signal sensing elements are installed inside the main body, and an insulating layer is sandwiched between the two signal sensing elements. The two signal sensing elements each have a signal transmission segment and a signal sensing segment that are electrically connected to each other, and each of the signal transmission segments consists of a planar antenna parallel to each other and has a meandering line type antenna shape, and in a plane in which each of the signal transmission segments is parallel to each other, the vertical projections of each of the antenna shapes do not completely overlap, and when a part of the main body forms an enclosing portion to surround the object to be measured, a part or all of the signal sensing segment is located in the enclosing portion.

[0011] As a result, the signal sensing device of the present invention can improve the effect of signal transmission by the meandering line type antenna shape of the signal transmission segments and the arrangement in a non-completely overlapping (transposition) manner.

[0012] The antenna shape has a meander step line width between 0.05 and 0.55 mm, a meander step spacing between 1 and 4 mm, a meander step total width and a meander step total length between 5 and 20 mm, respectively, and a thickness between 0.005 and 0.1 mm. Preferably, the meander step line width is between 0.15 and 0.2 mm, the meander step spacing is between 2 and 3 mm, the meander step total width and the meander step total length are between 14 and 16 mm, respectively, and the thickness ranges between 0.01 and 0.015 mm. Thus, the arrangement of the signal transmission segments in the above-mentioned specific antenna shape dimensions can significantly increase the strength of signal transmission when the signal sensing device is installed in the measurement object to sense signals.

[0013] Also, the vertical projections of the antenna shapes are not completely overlapped and have a dislocation interval, the dislocation interval being between 0.05 and 2 mm, preferably between 0.1 and 1.5 mm, and more preferably between 0.5 and 1.5 mm. Optionally, an X direction and a Y direction are defined in a two-dimensional coordinate system, and the vertical projections of the antenna shapes are not completely overlapped and have a dislocation interval in the X direction and a dislocation interval in the Y direction, the dislocation interval in the X direction and the dislocation interval in the Y direction being between 0.05 and 2 mm. In this way, the strength of signal transmission can be significantly increased by the arrangement of the dislocation intervals.

[0014] The body has a head and an extension, the extension being connected to the head and having a length extending outward from one end of the head, so that the whole or part of the extension surrounds the object to be measured. Thus, depending on the arrangement of the head and the extension, the signal sensing device can be applied to surround the object to be measured.

[0015] In addition, the signal transmission segment is installed in the head of the body, and the signal sensing segment is installed in the extension of the body. In this manner, the signal transmission segment and the signal sensing segment are arranged to correspond to the head or the extension, so that the structures of the transmission function and the sensing function of the signal sensing device can be appropriately arranged, and therefore the transmission signal and the sensing signal can be prevented from interfering with each other.

[0016] The head of the body has a length and width each between 5 and 35 mm, the extension has a width between 2 and 15 mm, and the head and extension each have a thickness between 0.05 and 0.350 mm. In this way, by arranging the various dimensional ranges described above, the signal sensing device can be applied in a specific environment with a limited space (e.g., in a living body of a size such as a human body, rabbit or mouse, or in a living body of an even larger size) and measure a signal for a specific measurement target (organ or tissue).

[0017] The signal amplifier further includes a signal amplifier having a plurality of protruding structures protruding outward from the main body, the protruding structures being cylindrical in shape, having a diameter between 250 and 400 μm, and a height between 40 and 75 μm, and a portion of the main body forming the surrounding portion, the signal amplifier abuts the object to be measured locally or entirely. In this way, the specific shape and dimensional arrangement of the protruding structures as described above can greatly increase the strength of signal detection when the signal sensing device surrounds the object to be measured and senses the signal.

[0018] In addition, the signal sensing device of the present invention is made of one or more biodegradable materials, and can be applied to measure a desired sensing signal by being installed in a living body, and can be completely decomposed within a certain period of time, so that there is no need to perform another surgery to remove it, and therefore the risk of reoperation can be avoided.

[0019] In addition, the main body further has an assembly structure, the assembly structure having a first assembly part and a second assembly part spaced apart from each other and installed on the main body, and when a part of the main body forms the surrounding part, the first assembly part and the second assembly part are aligned with each other. In this way, the first assembly part and the second assembly part of the assembly structure are aligned with each other, so that they can be conveniently and simply coupled to the assembly structure by another fixing member, and therefore the signal sensing device can be conveniently and simply installed on the measurement object.

[0020] The signal sensing device further includes a fixing member, and when the first assembly portion and the second assembly portion are aligned with each other, the fixing member is coupled to the first assembly portion and the second assembly portion to maintain the shape of the surrounding portion. In this manner, the signal sensing device can be fixed to the measurement object by coupling to the assembly structure by the fixing member.

[0021] In addition, the first assembly part and the second assembly part each have at least one through hole, the fixing member has a connecting part, an inserting part and a locking part, the inserting part extends outward from the connecting part, the locking part protrudes outward from one position of the inserting part, and when the fixing member is coupled to the first assembly part and the second assembly part, the inserting part is inserted into the through hole where the first assembly part and the second assembly part are aligned with each other, the connecting part is located on one side of the first assembly part and the second assembly part, and the locking part is locked on the other side of the first assembly part and the second assembly part. In this way, the arrangement of the fixing member and the assembly structure makes it possible to simplify the fixing member and the assembly structure and to fix the signal sensing device to the measurement object.

[0022] In addition, each of the through holes has a through hole diameter in the radial direction, the locking portion has an entry end and a locking end, the entry end is located at one end opposite to the connecting portion, the locking end is located between the connecting portion and the entry end, and the entry end is formed to have a shape that gradually widens toward the locking end, so that the length of the locking portion in the radial direction gradually increases in the axial direction. In this way, the arrangement of the locking portion of the fixing member that gradually widens in shape allows it to be easily connected to the assembly structure and has the effect of firmly connecting the fixing member and the assembly structure.

[0023] In addition, the first assembly part and the second assembly part each have two through holes, the insertion part of the fixing member forms two protruding structures corresponding to the number of the through holes, and the fixing member has an overall U-shape or V-shape. In this way, the number of through holes used in the assembly of the assembly structure is two, and the fixing member has a corresponding number of insertion parts, so that compared with a state in which there is only one through hole and one insertion part, the force between the fixing member and the assembly structure can be more uniformly received, and the stability of the connection between the fixing member and the assembly structure can be improved. Furthermore, compared with a state in which there are more than two through holes and insertion parts, the advantage of space utilization due to the miniaturization of the entire structure can be increased, and the shape of the fixing member and the assembly structure is relatively simple, so that the structure is simple and the cost can be reduced.

[0024] In addition, the main body further has a plurality of marking features, each of which is installed on the main body in alignment with the positions of the first assembly part and the second assembly part, thereby improving the convenience of alignment when mounting the assembly structure.

[0025] In addition, each of the marking features is a triangular cut, and the vertices of the triangular cut are aligned with the first assembly part and the second assembly part, thereby improving the convenience of alignment when mounting the assembly structure.

[0026] In addition, each of the marking features is a linear symbol, thus improving the convenience of alignment when mounting the assembly structure. [Brief description of the drawings]

[0027] [Figure 1] 1 is a schematic perspective view of a preferred embodiment of a signal sensing device of the present invention; [Diagram 2] 2 is a schematic diagram of the signal sensing device shown in FIG. 1 surrounding a measurement object; [Diagram 3]1 is a schematic perspective view of a preferred embodiment of a signal sensing element of the present invention; [Figure 4] FIG. 4 is a localized exploded schematic diagram of the signal sensing element shown in FIG. 3. [Diagram 5] FIG. 5 is a schematic top view of the rearrangement arrangement of the signal transmission segments shown in FIG. 4. [Figure 6] FIG. 1 is a schematic top view of the loop antenna shape of the antenna used in the comparison experiment. [Figure 7] 2 is a locally enlarged view of the signal amplifier shown in FIG. 1. [Figure 8] 2 is a schematic diagram of the characteristics of a venous blood vessel signal measured by a signal sensing device of the present invention; [Figure 9] FIG. 2 is a schematic perspective view of another preferred embodiment of a signal sensing device of the present invention; [Figure 10] FIG. 10 is a schematic diagram of the signal sensing device shown in FIG. 9 surrounding an object to be measured. [Figure 11] 11 is a schematic diagram of the signal sensing device shown in FIG. 10 fixed to an object to be measured. FIG. [Figure 12] FIG. 12 is a schematic cross-sectional view taken along line AA shown in FIG. 11. [Figure 13] 4 is another embodiment of the symbology feature of the signal sensing device of the present invention. BEST MODE FOR CARRYING OUT THEINVENTION

[0028] In order to make the above and other objects, features and advantages of the present invention clearer and easier to understand, the embodiments of the present invention will be described in detail with reference to the drawings as follows. Also, the same reference numerals in different drawings are regarded as the same, and the description thereof will be omitted.

[0029] 1 and 2 are respectively an example showing a signal sensing device according to an embodiment of the present invention and a state in which the signal sensing device surrounds a measurement object. The signal sensing device has a main body 1 and a signal sensing element 2. A part of the main body 1 is formed as an enclosure part and used to surround the measurement object T, and the signal sensing element 2 is installed inside the main body 1. Preferably, the measurement object T is a structure such as a biological organ or tissue. It should be noted that although the measurement object T shown in FIG. 2 is a blood vessel, the measurement object T is not limited to a blood vessel.

[0030] Optionally, the signal sensing device further has a signal amplification unit 3 installed on the main body 1, such that when a part of the main body 1 surrounds the object to be measured T, all or part of the signal amplification unit 3 comes into contact with the object to be measured T.

[0031] The body 1 is used to cover the signal sensing element 2, thereby protecting the signal sensing element 2 and preventing the signal sensing element 2 from being interfered with by the sensing environment. Optionally, the body 1 is formed in an elongated arrangement, and is preferably formed to surround the measurement object T in a relatively wide area. Optionally, the body 1 is formed in an elongated arrangement having uniform dimensions, for example, the width and thickness are respectively kept constant in the length direction. Optionally, as shown in Figures 1 and 2, the body 1 is formed in an elongated shape, has a head 1H and an extension 1E connected to each other, and the extension 1E extends outward from one end of the head 1H with a length, so that the whole or part of the extension 1E surrounds the measurement object T. In particular, a part of the ring formed by the extension 1E surrounds the measurement object T. Furthermore, when the extension 1E is formed into the ring, the free end of the extension 1E or a portion adjacent to the free end may be fixed to an appropriate portion of the extension 1E itself, so that the main body 1 can firmly surround the measurement target T. The method of fixing the extension 1E can be selected according to the actual situation and is not limited in the present invention.

[0032] Regarding the dimensional arrangement of the main body 1, particularly when the signal sensing device is installed inside the human body to measure blood vessels, as shown in FIG. 1, the head 1H of the main body 1 has a length LH (corresponding to the extension direction of the reference axis Y) and width W H (corresponding to the stretching direction of the reference axis X), both of which are between 5 and 35 mm, preferably between 10 and 30 mm, and more preferably between 15 and 20 mm; and a thickness T H (corresponding to the extension direction of the reference axis Z). The extension portion 1E has a width W E and has a width W E is between 2 and 15 mm, preferably between 5 and 10 mm, and the thickness T is between 0.05 and 0.35 mm. E and the length L of the extension portion 1E E can be arranged according to actual demand.

[0033] As shown in Fig. 1, the signal sensing element 2 is at least one in number, and has a signal transmission segment 2a and a signal sensing segment 2b electrically connected to each other, and is installed inside the body 1. When a part of the body 1 is formed as an enclosure to surround the measurement object T, a part or all of the signal sensing segment 2a is located in the enclosure. In detail, the signal transmission segment 2a is located in the head 1H of the body 1, and can be arranged, for example, by an antenna structure, so that the sensing signal generated from the signal sensing segment 2b, especially the sensing signal generated for the measurement object T, is converted into a transmission signal (e.g., electromagnetic wave) having a specific operating frequency and transmitted. In particular, the transmission signal is transmitted to a signal analysis device (not shown) to convert the transmission signal into the corresponding information to be measured, thereby performing related analysis or monitoring and management. The signal sensing segment 2b is located in the extension 1E of the main body 1, and extends and distributes in the area where the main body 1 is used to surround the measurement object T, thereby receiving information to be measured (e.g., blood flow velocity) in the measurement object T (e.g., blood vessel) and converting the information to be measured into a sensing signal (e.g., electrical signal). Then, the signal sensing segment 2b transmits the sensing signal to the signal transmission segment 2a, which generates a corresponding transmission signal. In detail, the transmission signal can be transmitted to a corresponding receiving unit (not shown), and the receiving unit converts the transmission signal into the information to be measured of the measurement object T by analyzing the received transmission signal according to a predetermined method, and observes, analyzes, monitors, or manages the change in the information to be measured.

[0034] Specifically, the antenna structure is formed in a flat antenna / planar antenna arrangement. The operating frequency is determined by the antenna pattern / shape possessed by the signal transmission segment 2a. In other words, different operating frequencies can be obtained by different antenna patterns with the same material and dimensions. The antenna pattern is, for example, at least one of a square loop, a circular loop, a triangular loop, an asymmetric loop, and other patterns. According to the present invention's research, when the signal sensing device of the present invention is installed in the human body, a preferable transmission effect can be obtained if the operating frequency is between 350MHz and 450MHz. More preferably, the operating frequency is between 401MHz and 406MHz. In this way, within the operating frequency range, the signal transmission segment 2a can transmit signals with stable signal quality.

[0035] Alternatively, as shown in FIG. 3, the signal sensing element 2 may be plural in number, and an insulating layer I may be provided between each of the signal sensing elements 2, and the signal sensing elements 2 may be isolated by the insulating layer I to avoid signal interference between each of the signal sensing elements 2. Preferably, the signal sensing element 2 is two in number, and the insulating layer I is sandwiched between the two signal sensing elements 2. The thicknesses of the signal transmission segment 2a and the signal sensing segment 2b of the signal sensing element 2 are both between 0.005-0.1 mm, corresponding to the arrangement directions of the length (reference axis X), width (reference axis Y) and thickness / height (reference axis Z) of the main body 1. The dimensional arrangement of the signal transmission segment 2a and the signal sensing segment 2b in the length and width are respectively arranged corresponding to the head 1H and the extension 1E of the main body 1, and in particular, the dimensions in the length and width are both smaller than those of the head 1H and the extension 1E, so that the signal sensing element 2 can be installed inside the main body 1.

[0036] In particular, as shown in Figures 3 to 5, according to the research of the present invention, when the number of signal sensing elements 2 is two, the signal transmission segments 2a of each signal sensing element 2 are made of parallel planar antennas and have a meander line type antenna shape, and are arranged in a transposition manner with an insulating layer I sandwiched therebetween so as to overlap each other (in the direction of the reference axis Z), and especially when the vertical projections of the antenna shapes of each signal transmission segment 2a do not completely overlap in a plane in which each signal transmission segment 2a is parallel to each other (such as the plane direction formed by the reference axes X and Y), the signal sensing element can be appropriately applied inside the human body, and the measured sensing signal can be converted into a high-quality transmission signal. More specifically, as shown in Figure 4, the meander line width W of the meander line type antenna shape is W The meandering step interval G is in the range of 0.05 to 0.55 mm, preferably in the range of 0.09 to 0.25 mm, and more preferably in the range of 0.15 to 0.2 mm. M The meandering step total width W is in the range of 1 to 4 mm, preferably 2 to 3 mm. M The meandering step length L is in the range of 5 to 20 mm, preferably in the range of 14 to 16 mm. M The range of thickness of the meandering step antenna is between 5 and 20 mm, preferably between 14 and 16 mm. The range of thickness of the meandering step antenna is between 0.005 and 0.1 mm, preferably between 0.01 and 0.05 mm, more preferably between 0.01 and 0.015 mm. It should be noted that the dimensions of each azimuth of the meandering step antenna, especially the dimensions of the head 1H in the corresponding azimuth, are smaller than those of the main body 1. Preferably, as shown in FIG. 5, the vertical projections of each of the antenna shapes do not completely overlap, and the transposition interval M A and the dislocation spacing M A The range of the dislocation spacing M is between 0.05 and 2 mm, preferably between 0.1 and 1.5 mm, and more preferably between 0.5 and 1.5 mm. A can be dislocated in the X and Y directions, and the dislocation interval in the X direction is M AX and the dislocation spacing in the Y direction MAyand the dislocation spacing M A is the dislocation spacing in the X direction, M AX and the dislocation spacing in the Y direction M Ay The length (M A 2 = M AX 2 + M Ay 2 ) and the dislocation spacing in the X direction M AX and Y-direction dislocation spacing M Ay Both are between 0.05 and 2 mm, preferably between 0.1 and 1.5 mm, and more preferably between 0.5 and 1.5 mm.

[0037] Referring to Table 1, the return loss and antenna efficiency values ​​obtained by various antenna arrangements and dimensional designs are shown. Arrangements 1 to 3 in Table 1 are antenna values ​​designed and published by a research team at Stanford University for an in-body blood signal detection device, in particular, the antenna shape is a loop (Spiral Antenna), and the arrangement is a square loop (shown as a single antenna AN) as shown in Figure 6. In addition, portions of data that cannot be obtained / estimated are displayed as "No Data". Arrangements 4 to 7 in Table 1 are research data for the present invention.

[0038] [Table 1]

[0039] As can be seen from Table 1, the layout 4 proposed by the present invention has the best effect. The layout 4 is based on the meandering line type antenna shape of the signal transmission segment 2a, and in particular, the meandering line width W W The range is between 0.15 and 0.2 mm, and the meandering step interval G M The range is between 2 and 3 mm, and the total width of the meandering step W M The range is between 14 and 16 mm, and the total length of the meandering section L A The range of is between 14 and 16 mm, the thickness range is between 0.01 and 0.015 mm, and the dislocation spacing M AThe range is between 0.5 and 1.5 mm.

[0040] It should be noted that the preferred operating frequency (401-406MHz) described in the present invention is defined according to the transmission standard of existing medical communication devices, and this frequency band belongs to the low range in wireless transmission, so it has better transmittance. Furthermore, in terms of antenna efficiency, the device of the present invention is installed within a few centimeters, even within 1 centimeter, under the skin during the actual application process. In addition, according to the research of the present invention, when the antenna efficiency is higher than about 0.010%, the transmitted signal strength can ensure the overall stability of the signal, so that the corresponding transmitted signal can be received by the receiving equipment installed outside the body.

[0041] In one embodiment in which the signal sensing device has a signal amplifier 3, as shown in Figures 1, 2 and 7, the signal amplifier 3 has a plurality of protruding structures 31 and is protruded from one outer side of the body 1, and the plurality of protruding structures 31 protrude outward from the outer side of the body 1 to form a shape of a plurality of protrusions. When a part of the body 1 forms an enclosing part to enclose the measurement object T, a part or the whole of the signal amplifier 3 is located in the enclosing part, and the signal amplifier 3 abuts the measurement object T locally or entirely. In detail, when the signal sensing device of the present invention is laid out on a plane as shown in Figure 1, the plurality of protruding structures 31 protrude from the body 1 in a direction away from the body 1. In particular, the signal amplifying unit 3 is protruded from the extending portion 1E of the main body 1 and is formed to be aligned with the signal sensing segment 2b of the signal sensing element 2, so that when the main body 1 surrounds the measurement object T, the plurality of protruding structures 31 of the signal amplifying unit 3 locally or entirely contacts the measurement object T, so that the signal amplifying unit 3 can contact the measurement object T more closely, thereby increasing the strength of the sensing signal corresponding to the information to be measured received by the signal sensing segment 2b. Optionally, the protruding structure 3 has a shape such as a cylindrical shape, a semicircular shape, a semi-elliptical shape, a trapezoidal shape, etc., but is not limited to the above shapes.

[0042] Preferably, when each protruding structure 31 contacts the measurement object T, it is pressed in partially or entirely into the measurement object T. In particular, the pressed-in state is such that the measurement object T is softer than the plurality of protruding structures 31, and as the state in which the main body 1 surrounds the measurement object T changes from a loose state to a tight state, the depth of the recess in the area where the measurement object T contacts the measurement object T is changed from shallow to deep by each protruding structure 31 that contacts the measurement object T. It should be noted that the pressed-in state is preferably in principle such that it does not affect the normal function of the measurement object T and does not damage the measurement object T. In this way, by pressing in partially or entirely into the measurement object T, the contact area between the signal amplifier 3 and the measurement object T can be increased, and further, the intensity of the sensing signal corresponding to the information to be measured received by the signal sensing segment 2b can be increased.

[0043] The length, width and height of each protruding structure 31 in the signal amplifying section 3 are all between 0.1 and 500 μm. In particular, according to the research of the present invention, when the shape of the protruding structure 31 is cylindrical, the strength of the sensed signal can be significantly increased. More specifically, in an arrangement in which the shape of the protruding structure 31 is cylindrical, the diameter is between 10 and 500 μm, preferably between 250 and 400 μm, and more preferably between 300 and 350 μm. The height is between 1.5 and 100 μm, preferably between 40 and 75 μm, and more preferably 50 μm. There is a gap between each protruding structure 31, and the gap is 1.5 to 5 times the diameter, and preferably 2 to 3.5 times the diameter.

[0044] It should be noted that, based on the shape and dimensions of the protruding structure 31 proposed by the present invention, when the signal sensing device of the present invention measures the vascular signal of an artery or vein, especially when measuring the vascular signal of a vein, it can stably obtain the change tendency of the blood flow velocity regardless of whether the blood vessel is contracting or diastolic. In detail, as shown in FIG. 8, the signal sensing device having the protruding structure 31 of the present invention can surround a venous blood vessel (measurement object T) of a living body and measure its signal characteristics, thereby measuring a proximal blood vessel signal, a distal blood vessel signal, and a normal blood vessel signal. The definition of "proximal" is a signal measured at a position about 5 mm away from the vascular clamp by placing a vascular clamp (not shown) on the venous blood vessel to be measured, reducing the blood flow velocity (signal strength) downstream of the clamp, and placing the signal sensing device downstream of the clamp. The definition of "distal" is a signal measured at a position about 10 mm away from the vascular clamp by placing the signal sensing device downstream of the clamp. The definition of "normal" is a signal measured by the signal sensing device when the venous blood vessel to be measured is in a natural state without placing the vascular clamp. Meanwhile, compared to the comparative experiment (experiment published by Stanford University), the comparative experiment used a pyramidal protruding structure, the base (length of the maximum side) of the pyramidal protruding structure was 50 μm, and the minimum spacing between the edges of each protruding structure was 40 μm. However, the comparative experiment was only able to measure the change in blood flow velocity in the artery. In addition, since veins are the places where thrombus is most likely to occur after surgery, it is necessary to monitor the venous vascular signal to a high degree. However, since the blood flow fluctuation / signal of venous blood vessels is smaller than that of arterial blood vessels, it may be difficult to measure the signal. Therefore, the present invention overcomes the limitation of the comparative experiment that only arterial vascular signals can be measured, making the measured signal more valuable as a reference. In particular, although the present invention simulates the state of venous vascular occlusion by vascular clamping, the signal sensing device of the present invention can still measure the corresponding blood flow signal, which can reflect the change in blood flow in the blood vessel to be monitored, thereby greatly improving the application range of vascular signal monitoring. Furthermore, it should be noted that the experimental experiment of the present invention was performed on the veins of living animals (such as rabbits).In particular, although the diameter of the veins of the experimental living organism is smaller than that of the human body, the signal sensing device of the present invention can still measure decipherable signals of stable quality, further proving that it has excellent performance in signal transmission and sensing effect.

[0045] As shown in Fig. 9-12, another embodiment of the signal sensing device of the present invention is shown, in particular with an optional assembly structure 11 and a corresponding fixing member 4. As shown in Fig. 9, the main body 1 has the assembly structure 11, the assembly structure 11 has a first assembly part 11A and a second assembly part 11B, the quantity of the first assembly part 11A and the second assembly part 11B is at least one each, and the first assembly part 11A and the second assembly part 11B are installed with a space between them. In particular, when the quantity of either the first assembly part 11A or the second assembly part 11B is more than one, the multiple assembly parts (the first assembly part 11A and / or the second assembly part 11B) are all installed with a space between them. Preferably, the first assembly part 11A and the second assembly part 11B are installed at the extension part 1E of the main body 1, and the first assembly part 11A is installed at one position at the free end closer to the extension part 1E than the second assembly part 11B.

[0046] As shown in Figures 10 and 11, when the main body 1 is formed into a ring shape (e.g., by bending), particularly when the main body 1 forms the ring shape to surround the measurement object T, the first assembly part 11A and the second assembly part 11B are arranged so that they can be aligned with each other, particularly aligned so that they overlap and contact each other. At this time, in order to ensure that the first assembly part 11A and the second assembly part 11B are aligned with each other, and the main body 1 is arranged to surround and / or fix the measurement object T, the first assembly part 11A and the second assembly part 11B are further coupled with a fixing member 4 to maintain the shape of the surrounding part. In detail, the coupling refers to the fixing member 4, the first assembly part 11A and the second assembly part 11B having a recessed feature or a protruding feature for fitting each other structurally, and can be realized by one or more of, for example, a snap-fit, structural tension and flexibility.

[0047] Optionally, the first assembly part 11A and the second assembly part 11B each have at least one through hole. The fixing member 4 has a connecting part 41, an inserting part 42 and a locking part 43. The inserting part 42 extends outward from the connecting part 41 and has a free end, which is formed away from the connecting part 41. The locking part 43 protrudes outward from a position of the inserting part 42 and is spaced from the connecting part 41. Preferably, the locking part 43 protrudes from the free end of the inserting part 42. When the fixing member 42 is connected to the first assembly part 11A and the second assembly part 11B, the insertion part 42 is inserted into a through hole in which the first assembly part 11A and the second assembly part 11B are aligned with each other, the connecting part 41 is located on one side of the first assembly part 11A and the second assembly part 11B, and the locking part 43 is locked to the other side of the first assembly part 11A and the second assembly part 11B.

[0048] 11 and 12, each through hole has a through hole diameter in the radial direction (such as the direction of a plane formed by the reference axes X and Y) and the axial direction (such as the direction extending from the reference axis Z) of the through hole. The connecting portion 41 is located outside the assembly structure 11 and protrudes from the through hole in the radial direction, so that when the fixing member 4 and the assembly structure 11 are coupled, the connecting portion 41 of the fixing member 4 is located on one side of the assembly structure 11 (i.e., on one side of the first assembly part 11A and the second assembly part 11B) without passing through the through hole. The inserting portion 42 extends in the axial direction, and its shape or contour in the axial direction can pass through the through hole of the assembly structure 11. The locking portion 43 has an entry end 43a and a locking end 43b, the entry end 43a is located at one end opposite the connecting portion 41 or at one end away from the connecting portion 41, and the locking end 43b is located between the connecting portion 41 and the entry end 43a. When the fixing member 4 and the assembly structure 11 are connected, the locking end 43b of the locking portion 43 is locked to the other side of the assembly structure 11.

[0049] Preferably, the entry end 43a is formed to have a shape that gradually widens toward the locking end 43b, and the length of the locking portion 43 in the radial direction gradually increases in the direction along the axial direction. In this manner, the locking portion 43 is formed so that its length in the radial direction gradually widens toward the connecting portion 41, whereby the entry end 43a of the locking portion 43 can be easily inserted and can easily pass through the through hole formed so that the first assembly portion 11A and the second assembly portion 11B are aligned by overlapping each other, and further, after the locking portion 43 passes through the through hole, the locking end 43b protrudes from the through hole in the radial direction. In this way, after the engaging portion 43 passes through the through hole, the connecting portion 41 is located on one side of the assembly structure 11, and the engaging end 43b is engaged with the other side of the assembly structure 11, and further, the connecting portion 41 and the engaging end 43b each protrude radially from the through hole, thereby forming an inseparable connection between the first assembly portion 11A and the second assembly portion 11B, so that the signal sensing device of the present invention can be fixed to surround the measurement object T.

[0050] Based on the above description of the assembly structure 11 and the fixing member 4, in the present invention, the number of the through holes may be one or more, and the through holes of the first assembly part 11A and the through holes of the second assembly part 11B can be aligned with each other according to design in terms of the number, position, shape, etc. Furthermore, corresponding inserting parts 42 are installed on the fixing member 41 in accordance with the arrangement of the through holes. In a preferred embodiment of the present invention, as shown in Figs. 9 to 12, the first assembly part 11A and the second assembly part 11B each have two through holes, the inserting part 42 of the fixing member 4 has two protruding structures corresponding to the number of the through holes, and the fixing member 4 has an overall U-shaped or V-shaped shape. It should also be noted that the number of the through holes of the first assembly part 11A and the second assembly part 11B shown in the drawings of the present invention is two, but is not limited thereto.

[0051] In detail, the diameter of the through holes of the first assembly portion 11A and the second assembly portion 11B is the width W of the extension portion 1E. E The distance between the centers of the two through holes in the first assembly section 11A and the second assembly section 11B is 1.5 to 6 times the diameter of the through holes, preferably 1.5 to 3 times, more preferably 1.5 to 2 times. The sum of the diameter of the through holes and the distance between the through holes is less than the width W of the extension section 1E in which they are installed. E It must be smaller.

[0052] Optionally, as shown in Figures 9 to 11, the main body 1 may further have a plurality of marked features M, each of which is disposed on the main body 1 so as to be aligned with the positions of the first assembly part 11A and the second assembly part 11B, thereby marking / indicating the positions of the first assembly part 11A and the second assembly part 11B. Each of the marked features M is a cut, preferably a triangular cut, and more preferably, the apex of the triangle is aligned with the first assembly part 11A and the second assembly part 11B.

[0053] Optionally, as shown in FIG. 13, each marking feature M is a line-type mark, preferably a straight-line mark, and is selectively extended to the side of the body 1 or installed only on the side of the body 1, so that when the first assembly part 11A and the second assembly part 11B are aligned, the straight-line marks of the first assembly part 11A and the second assembly part 11B are connected in a straight line on the side of the body 1. The side of the body 1 refers to at least one of both sides facing each other in the width direction, or at least one of both sides facing each other on the reference axis X as shown in FIG. 11, or at least one of both sides facing each other in the axial direction of the surrounding part when the body 1 forms the surrounding part. In particular, each marking feature M used for alignment is located on the same side of the body 1.

[0054] Due to the above-mentioned marking feature M, when the marking features M of the first assembly part 11A and the second assembly part 11B are aligned, for example when the cuts overlap (as shown in Figures 9 to 11) or when the linear symbols are arranged in a specific shape (as shown in Figure 13), it indicates that the first assembly part 11A and the second assembly part 11B are already aligned. Therefore, when a user installs the signal sensing device of the present invention on the measurement object T, the first assembly part 11A and the second assembly part 11B can be more easily aligned by the marking feature M, thereby fixing the main body 1 to the measurement object T.

[0055] It should be noted that the marking feature M is a marking that is visually different from the main body 1 (particularly the difference between the main body 1 and the measurement target T), and is an indicative feature or a distinguishable feature formed by any one or any combination of colors, characters, symbols, designs, symbols and structural arrangements (e.g., protrusions or cuts), etc. Therefore, the form of the marking feature M is not limited to the above-mentioned cuts (as shown in Figs. 9 to 11) and linear symbols (as shown in Fig. 13).

[0056] According to the above-mentioned structural arrangement of the signal sensing device of the present invention, the signal sensing device can be entirely (particularly entirely) made of biodegradable materials, particularly biodegradable materials approved by the US Food and Drug Administration (FDA). In this way, the signal sensing device can be particularly installed in the body of a target organism and decompose within a predetermined period of time, and does not require surgery to remove it, thereby avoiding the risk of reoperation. The predetermined period is, for example, 3 to 26 weeks, preferably 13 to 26 weeks. However, the predetermined period can be changed in terms of material, thickness, etc. according to the actual required period of signal monitoring, and is not limited to the above-mentioned exemplary time. As a specific application example, the signal sensing device can be embedded in a human body to measure the blood flow velocity (corresponding to the information to be measured) of a blood vessel (corresponding to the measurement target T).

[0057] Regarding the degradable materials, the body 1 and the insulating layer I may be made of at least one of polyhydroxybutyrate (PHB), polyhydroxyvalerate (PHV) and poly-L-lactic acid (PLLA). The signal sensing element 2 may be made of a biodegradable metal, preferably magnesium metal. The signal amplifying part 3 may be selected from polycaprolactone (PCL). The fixing member 4 may be selected from polydioxanone and L-lactide glycolide polymer.

[0058] The thing to pay attention to is the thickness of the main body 1, especially the thickness T of the head 1H. H and the thickness T of the extension part 1E E refers to the overall thickness formed by the body 1 including the sandwiched signal sensing element 2 and other optional components (eg, insulating layer I).

[0059] In summary, the signal sensing device of the present invention can enhance the effect of signal transmission by the meandering line type antenna shape of the signal transmission segment and the arrangement by the transposition method. The protruding structure of the signal amplifier is protrudingly provided on the extension part of the main body, and is aligned with the signal sensing segment located on the signal sensing element of the extension part of the main body, so that the strength of the sensing signal corresponding to the information to be measured received by the signal sensing segment can be strengthened. The protruding structure is cylindrical in shape, has a diameter of about 250 to 400 μm, and a height of about 40 to 75 μm, so that the strength of the sensing signal can be further strengthened. Depending on the dimensions of the main body, the signal sensing element, and the signal amplifier, the device can be applied to the measurement of signals in specific organs or tissues inside a living body (especially the human body), especially the measurement of signals in blood vessels. The signal sensing device of the present invention can be made entirely of biodegradable materials, and due to its overall dimensions, it is suitable for installation inside the human body, can measure the desired sensing signal, and can be completely decomposed within a predetermined period of time, so that surgery for removal is not required and the risk of reoperation can be avoided. In addition, the arrangement of the assembly structure allows it to be coupled with a fixing member, so that the signal sensing device can be fixed to the object to be measured, and the arrangement of the marking features allows the assembly structure to be more easily aligned.

[0060] Although the present invention has been described using the preferred embodiments described above, they are not intended to limit the present invention. Any person familiar with this technology may make various changes or modifications to the above-described embodiments without departing from the spirit and scope of the present invention, and these changes or modifications will still fall within the technical scope protected by the present invention. Therefore, the scope of protection of the present invention should naturally include the meaning described in the appended claims and modifications within the equivalent scope thereof. [Explanation of symbols]

[0061] 1 Main unit 1H head 1E Extension part 11 Assembly structure 11A First Assembly Section 11B Second Assembly Section 2 Signal sensing element 2a Signal transmission segment 2b Signal sensing segment 3. Signal Amplification Section 31 Protruding structure 4 Fixing member 41 Connection part 42 Insertion section 43 Fixing member 43a Approach end 43b Locking end AN Antenna G M Serpentine step spacing I Insulation layer L E length L H length L M Serpentine section length M marked sexual characteristics M A Dislocation Spacing M Az X-direction dislocation spacing M Ay Y-direction dislocation spacing T Measurement object T E Thickness T H Thickness W E width W H width W M Total width of serpentine steps W W Meander line width X Reference axis direction Y reference axis direction Z reference axis direction

Claims

1. a body and two signal sensing elements; Two signal sensing elements are installed inside the body, and an insulating layer is sandwiched between the two signal sensing elements, and each of the two signal sensing elements has a signal transmission segment and a signal sensing segment electrically connected to each other, and each of the signal transmission segments is made of a parallel planar antenna and has a meandering line type antenna shape, and in the plane where each of the signal transmission segments is parallel to each other, the vertical projection of each of the antenna shapes does not completely overlap and has a dislocation interval, and the dislocation interval is between 0.05 and 2 mm; A signal sensing device characterized in that, when a part of the main body is formed as an enclosing part to surround an object to be measured, a part or all of the signal sensing segments are located in the enclosing part.

2. 2. The signal sensing device of claim 1, wherein the antenna geometry has a meander step line width between 0.05 and 0.55 mm, a meander step spacing between 1 and 4 mm, a meander step total width and length each between 5 and 20 mm, and a thickness between 0.005 and 0.1 mm.

3. 3. The signal sensing device of claim 2, wherein the meander step line width is between 0.15 and 0.2 mm, the meander step spacing is between 2 and 3 mm, the meander step total width and the meander step total length are each between 14 and 16 mm, and the thickness range is between 0.01 and 0.015 mm.

4. 3. The signal sensing device of claim 2, wherein the vertical projections of each of said antenna shapes do not completely overlap and have a displacement spacing, said displacement spacing being between 0.1 and 1.5 mm.

5. 4. The signal sensing device of claim 3, wherein the vertical projections of each of said antenna shapes do not completely overlap and have a displacement spacing, said displacement spacing being between 0.5 and 1.5 mm.

6. 2. The signal sensing device of claim 1, wherein an X direction and a Y direction are defined in a two-dimensional coordinate system, the vertical projections of the antenna shapes do not completely overlap, have a dislocation interval in the X direction, and have a dislocation interval in the Y direction, and the dislocation interval in the X direction and the dislocation interval in the Y direction are between 0.05 and 2 mm.

7. The signal sensing device described in any one of claims 1 to 6, characterized in that the main body has a head and an extension portion, the extension portion being connected to the head and extending outward from one end of the head with a single length, thereby surrounding the object to be measured by all or part of the extension portion.

8. 8. The signal sensing device according to claim 7, wherein the signal transmission segment is disposed at the head portion of the body, and the signal sensing segment is disposed at the extension portion of the body.

9. 9. The signal sensing device of claim 8, wherein the head of the body has a length and width each between 5 and 35 mm, the extension has a width between 2 and 15 mm, and the head and extension each have a thickness between 0.05 and 0.350 mm.

10. 7. The signal sensing device according to claim 1, further comprising a signal amplifier, the signal amplifier having a plurality of protruding structures protruding outward from the main body, the shape of the protruding structure being cylindrical, having a diameter between 250 and 400 μm, and having a height between 40 and 75 μm, and wherein a part of the main body forms the surrounding portion, the signal amplifier abuts against the object to be measured locally or entirely.

11. 11. The signal sensing device of claim 10, wherein the diameter of the protruding structure is between 300 and 350 [mu]m and the height of the protruding structure is 50 [mu]m.

12. The signal sensing device according to any one of claims 1 to 6, characterized in that the signal sensing device is made of one or more biodegradable materials.

13. A signal sensing device as described in any one of claims 1 to 6, characterized in that the main body further has an assembly structure, the assembly structure having a first assembly part and a second assembly part installed on the main body with a gap between them, and when a portion of the main body forms the surrounding portion, the first assembly part and the second assembly part are aligned with each other.

14. 14. The signal sensing device of claim 13, further comprising a fixing member, the fixing member being coupled to the first assembly portion and the second assembly portion to maintain the shape of the surrounding portion when the first assembly portion and the second assembly portion are aligned with each other.

15. 15. The signal sensing device of claim 14, wherein the first assembly part and the second assembly part each have at least one through hole, the fixing member has a connecting part, an inserting part and a locking part, the inserting part extends outward from the connecting part, the locking part protrudes outward from one position of the inserting part, and when the fixing member is coupled to the first assembly part and the second assembly part, the inserting part is inserted into a through hole where the first assembly part and the second assembly part are aligned with each other, the connecting part is located on one side of the first assembly part and the second assembly part, and the locking part is locked to the other side of the first assembly part and the second assembly part.

16. The signal sensing device of claim 15, characterized in that each of the through holes has a through hole diameter in the radial direction, the locking portion has an entry end and a locking end, the entry end is located at one end opposite the connecting portion, the locking end is located between the connecting portion and the entry end, and the entry end is formed to have a shape that gradually widens toward the locking end, such that the radial length of the locking portion gradually increases in the direction along the axial direction of the through hole.

17. 16. The signal sensing device of claim 15, wherein the first assembly portion and the second assembly portion each have two through holes, the insertion portion of the fixing member forms two protruding structures corresponding to the number of the through holes, and the fixing member has an overall U-shaped or V-shaped shape.

18. 14. The signal sensing device of claim 13, wherein the body further comprises a plurality of marking features, each of the marking features being mounted on the body in registration with the positions of the first assembly portion and the second assembly portion.

19. 20. The signal sensing device of claim 18, wherein each said symbolic feature is a triangular cut, vertices of said triangular cut being aligned with said first assembly portion and said second assembly portion.

20. 20. The signal sensing device of claim 18, wherein each said symbolic feature is a line symbol.

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