A one-handed drug delivery device for the skin
The one-handed skin drug injection device addresses the limitations of existing electroporation devices by incorporating an eccentric electrode plate and thermoelectric cooling, enabling efficient and comprehensive one-handed drug delivery and skin care.
Patent Information
- Application Number
- JP2024031316
- Authority / Receiving Office
- JP · JP
- Patent Type
- Patents
- Current Assignee / Owner
- Priority Date
- 2023-03-08
- Filing Date
- 2024-03-01
- Publication Date
- 2025-03-19
- Estimated Expiration
- 2044-03-01
AI Technical Summary
Existing drug injection devices using electroporation methods face limitations in drug delivery due to strong stimulation sensations and limited drug input when using strong electrical pulses, and they lack the functionality to simultaneously administer drugs and provide cooling effects, requiring separate devices for each function.
A one-handed skin drug injection device with a detachable drug injector and an eccentric electrode plate that allows for one-handed operation, incorporating a heat exchanger and thermoelectric element to provide cooling while delivering drugs through electroporation.
Enables efficient one-handed operation for drug delivery and skin cooling, allowing for comprehensive facial care without the need for separate devices, thereby improving user convenience and treatment effectiveness.
Smart Images

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Abstract
Description
[Technical field]
[0001] The present invention relates to a one-handed operable skin drug injection device, and more specifically, to a one-handed operable skin drug injection device which is configured so that a drug injector containing a drug can be attached and detached to a grippable handpiece, and which is configured so that the attached drug injector can be operated while gripping the handpiece with one hand, and which is configured so that the electrode plate that directly contacts the skin is eccentric, thereby allowing the one-handed operable skin drug injection device to be used with one hand, and which allows the entire face to be cared for using the one-handed operable skin drug injection device with one of the eccentric electrode plates. [Background technology]
[0002] In general, drug injection devices that use the principle of electroporation are mainly used for skin cosmetic procedures, plastic surgery, and treatment of specific parts of the body. They use electrical pulses to temporarily create pores on the skin surface, allowing drugs to be easily injected into the skin cells. This means that effective drugs can be directly injected into the skin without using needles.
[0003] The drug injection device, which uses the principle of electroporation described above, is a method of allowing substances with a certain molecular weight (40,000 Daltons or less) to pass through cell membranes by disrupting the phospholipid bilayer with an electric pulse, creating temporary holes on the skin surface, allowing the drug to enter the cells through the holes.
[0004] At this time, the holes close the moment the electric pulse stops. The treatment that utilizes this is called electroporation, which is a non-chemical method that can deliver not only DNA but also many types of external substances into living cells without changing the biological structure and function of the cells.
[0005] As a result, the drug delivery device using electroporation does not directly irritate the skin, minimizing the patient's resistance to the treatment. It not only has a massage effect through the treatment, but also has the advantage that the treatment time is short and there is no damage to the skin, allowing the patient to resume daily life immediately after the treatment. It is also known to have the advantage that the effect is maximized when used in conjunction with other skin equipment.
[0006] However, the drug delivery device described above applies a strong electrical pulse to the skin surface through an electrode plate that touches the skin, so if the strength of the electrical pulse applied to the skin surface becomes large, the only option is to reduce the output strength due to the strong stimulating sensation.
[0007] Therefore, there is a drawback in that the amount of drug injected into the skin cell tissue is also limited.
[0008] To compensate for this functional shortcoming, a Cryocell treatment device that does not limit the amount of drug administered has been additionally used.
[0009] The CryoCell treatment device maximizes drug penetration without the use of injections, in conjunction with moisture penetration into the skin. This cools the skin surface, reducing strong irritation and pain even when a strong current is applied, and during drug penetration, it constricts blood vessels so that the penetrated drug remains in the skin tissue without being absorbed by the blood vessels.
[0010] Since the drug injection device using electroporation and the cryocell treatment device are independent products with different functions, it was necessary to purchase all of them in order to use these functions, which placed a financial burden on users due to the need to purchase them separately. Furthermore, since two or more types of devices must be used sequentially or in parallel for treatment purposes, it is inconvenient to carry and store them, as well as to use them.
[0011] In other words, the drug injection device using electroporation and the cryocell treatment device do not have the function of simultaneously performing drug injection and cooling effects, respectively, and therefore the effect of drug injection through the device is not superior. Therefore, in order to maximize the effect of drug injection, it has been conventionally inconvenient to perform the drug injection and cooling functions separately using each device through the drug injection device and the cryocell treatment device.
[0012] Taking these points into consideration, Patent Document 1 has proposed a drug injection device that is delivered through the skin.
[0013] In detail, a conventional transdermal drug injection device includes a tube body having a connection hole formed on its outer periphery and a screw portion formed on its front end; a drug injection tube which is composed of multiple tubes having different diameters and which are inserted from the rear end to the front end of the body and connected to each other by clamping, and a drug container is connected to the rear end tube; a handle which is screwed into the connection hole formed on the outer periphery of the body and guides a water supply hose, a cold / hot element cable, and a power cable; a fixing bracket which is located on the front end of the body and forms holes through which the water supply hose, the front tube of the drug injection tube, and the cold / hot element cable can pass; a water bucket which stores water supplied through the water supply hose so that the water supply hose can be connected to it; a cold / hot element which is in close contact with the water bucket and to which the cold / hot element cable is connected; an electrode plate which is electrically connected to the power cable to generate an electric pulse and cool the skin surface by being in close contact with the cold / hot element, and a cap which is screwed into the body to cover the water bucket, the cold / hot element, and the electrode plate.
[0014] However, the conventional transdermal drug injection device configured as above has a drawback in that a user must hold the handle with one hand and operate the drug injection tube with the other hand when injecting drugs, which means that the user cannot do other work while using the transdermal drug injection device. In addition, the electrode plate has a simple circular cross section, which means that it is not possible to treat areas such as around the eyes and nose. [Prior art documents] [Patent documents]
[0015] [Patent Document 1] Republic of Korea Patent No. 10-1052274 Summary of the Invention [Problem to be solved by the invention]
[0016] The present invention has been devised to solve the above-mentioned problems, and aims to provide a one-handed drug injection device by forming a drug injector stored in a grippable handpiece so that the attached drug injector can be operated while gripping the handpiece with one hand, and by configuring the electrode plate that directly contacts the skin as eccentric, the one-handed drug injection device can be used with one hand, and the eccentric electrode plate allows the entire face to be cared for using a single one-handed drug injection device.
[0017] Other objects of the invention will become apparent as the art progresses. [Means for solving the problem]
[0018] In order to achieve the above object, the present invention provides a one-handed operation skin drug injection device, comprising: a main body 110 which is divided into two parts and joined together to form an installation space inside and which is formed in a tubular shape with a front end and a rear end communicated therewith and which has an outer peripheral mounting part 111; a drug storage part 11 which is detachably attached to the mounting part 111 of the main body 110 and has an injection port 11a at the other end so that a drug can be stored and discharged; and a push part 12 which is inserted into the drug storage part 11 so that one end can move forward and backward, the drug storage part 11 of the drug sprayer 10 being elastically attached and detached to enable a patient to operate the push part 12 of the drug sprayer 10 while holding the main body 110 with one hand; and a mounting member 120 which is installed on one side inside the main body 110 and has cooling water supply units on the left and right sides of the one side so as to correspond to the control of a control unit. The heat exchanger includes a heat exchange member having a cooling water inlet portion and an outlet portion, one side of which is in close contact with the other side of the heat exchange member and a thermoelectric element cable connected to a positive terminal and a negative terminal capable of transmitting cooling heat is wired. A contact portion is electrically connected to a power cable for supplying power so as to generate an electric pulse, a portion of which is inserted inside the front end of the main body, and one side of which is in close contact with the thermoelectric element. The contact portion is fixed to the heat exchange member through a plurality of fixing screws. An electrode plate is formed on a contact portion that is expanded from the other side of the contact portion to be exposed to the outside of the front end of the main body and receives the cooling heat supplied from the thermoelectric element and cools the skin surface.
[0019] In addition, the mounting portion 111 of the main body portion 110 described above is characterized by being composed of a pair of mounting grooves 111a spaced apart from each other on the outer peripheral surface of the main body portion 110 so that the mounting member 120 can be elastically attached and detached, and mounting protrusions 111b each having one end integrally connected to the outer peripheral surface of the main body portion 110 and the other end protruding upward, with one side of each being open, thereby opening a portion of the mounting grooves 111a and allowing the mounting member 120 to be attached and detached.
[0020] The mounting member 120 is formed in a rectangular shape with both sides curved, and has a laterally concave mounting groove 121 on the top surface into which the drug storage portion 11 of the drug sprayer 10 can be mounted, and mounting protrusions 122 that can be inserted into the mounting portion 111 of the main body 110 are formed on one and the other sides of the bottom surface of the mounting groove 121, and pressure fixing protrusions 123 that can pressurize and fix the outer periphery of the drug storage portion 11 of the drug sprayer 10 are formed to protrude from the inner surfaces facing each other of the mounting groove 121, and an incision is made starting from both sides of the pressure fixing protrusions 123 to the top surface, thereby forming elastic holes 124 so that the pressure fixing protrusions 123 can elastically pressurize and fix the outer periphery of the drug storage portion 11. Effect of the Invention
[0021] As described above, according to the present invention, the skin drug injection device capable of being operated with one hand has a drug injector stored in a grippable handpiece that is detachably formed, and is configured so that the attached drug injector can be operated while gripping the handpiece with one hand, and one side of the electrode plate that directly contacts the skin protrudes eccentrically, so that the skin drug injection device can be used with one hand, and the eccentric electrode plate has the effect of allowing the entire face, including the areas around the eyes and nose, to be cared for with a single skin drug injection device. [Brief description of the drawings]
[0022] [Figure 1] 1 is a perspective view showing a one-handed operable transdermal drug injection device according to the present invention; [Diagram 2] 2 is a view showing a state in which a mounting member of the one-handed operable transdermal drug administration device according to the present invention is disassembled from a main body. [Diagram 3] 1 is a partially exploded view of a transdermal drug administration device operable with one hand according to the present invention; [Figure 4] 1 is a cross-sectional view showing a one-handed operable transdermal drug administration device according to the present invention; DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS
[0023] Hereinafter, a detailed description will be given of an embodiment of a one-handed dermal drug administration device according to the present invention.
[0024] First, it should be noted that in the drawings, the same components or parts are denoted by the same reference numerals as much as possible. In describing the present invention, detailed descriptions of related known functions or configurations are omitted in order to avoid making the gist of the invention unclear.
[0025] As shown in the drawings, the one-handed operable skin drug injection device 100 according to the present invention comprises a main body 110 which is divided into two parts and joined together to form an installation space inside, a tube body with a front end and a rear end connected to each other, and a mounting part 111 formed on the outer circumferential surface, a drug storage part 11 which is detachably attached to the mounting part 111 of the main body 110 at one end and has an injection port 11a for storing and discharging a drug at the other end, and a pushing part 12 which is inserted into the drug storage part 11 so as to be movable forward and backward, and a mounting member 120 which is formed so that the drug storage part 11 can be elastically attached and detached to enable a patient to operate the pushing part 12 of the drug sprayer 10 while holding the main body 110 with one hand, and a cooling water supply pipe and a discharge pipe which correspond to the control of the control unit are provided on the left and right sides of the one side of the mounting member 120. the heat exchange member 130 having a cooling water inlet 131 and an outlet 132 formed therein so that cooling water is supplied and circulated to perform heat exchange; a thermoelectric element 140 having one side closely attached to the other side of the heat exchange member 130, connected to a positive terminal and a negative terminal so as to be able to transmit cooling heat, and having a thermoelectric element cable wired thereto; a contact part 151 electrically connected to a power supply cable so as to generate an electric pulse, a part of which is inserted into the inside of the front end of the main body 110 so as to be fixed to the heat exchange member 130 having one side closely attached to the thermoelectric element 140 via a plurality of fixing screws; and an electrode plate 150 formed in a contact part 152 which is expanded from the other side of the contact part 151 and exposed to the outside of the front end of the main body 110 and receives the cooling heat supplied from the thermoelectric element 140 and cools the skin surface.
[0026] Hereinafter, the above-mentioned one-handed dermal drug administration device according to the present invention will be described in more detail with reference to the accompanying Figs. 1 to 4. Figs.
[0027] First, the main body 110 of the one-handed transdermal drug administration device according to the present invention is divided into two parts and connected to each other via a plurality of fixing screws, thereby forming an installation space inside in which the heat exchange member 130, the thermoelectric element 140, and the contact portion 151 of the electrode plate 150 can be disposed, and the front and rear ends are formed of a tube body for wiring a cooling water supply pipe and a discharge pipe, a thermoelectric element cable, and a power supply cable, and the outer circumferential surface is formed with a mounting part 111 for attaching and detaching the mounting member 10, and fixing holes 110a are formed on both sides of the outer circumferential surface of one side of the mounting part 111 to which the contact portion 151 of the electrode plate 150 can be fixed via screws.
[0028] In addition, the mounting portion 111 of the main body portion 110 described above is composed of a pair of mounting grooves 111a spaced apart from each other on the outer peripheral surface of the main body portion 110 so that the mounting member 120 can be elastically attached and detached, and mounting protrusions 111b each having one end integrally connected to the outer peripheral surface of the main body portion 110 and the other end protruding upward, with one side of each being opened so that a portion of the mounting grooves 111a is opened to attach and detach the mounting member 120.
[0029] The front end of the body 110 is further provided with a locking protrusion 112 bent inwardly so as to be locked with the contact portion 151 of the electrode plate 150 and increase the fixing force.
[0030] The above-mentioned mounting member 120 is formed so as to be able to elastically connect and separate the drug storage portion 11 of the drug sprayer 10, which is composed of a drug storage portion 11 having an injection port 11a at one end which is detachable from the mounting portion 111 of the main body portion 110 and a pushing portion 12 having one end which is inserted into the drug storage portion 11 so as to be able to move forward and backward, and the patient can operate the pushing portion 12 of the drug sprayer 10 while holding the main body portion 110 with one hand.
[0031] That is, the mounting member 120 is formed in a rectangular shape with both sides curved, and has a mounting groove 121 that is concave in the horizontal direction on the top surface so that the drug storage portion 11 of the drug sprayer 10 can be mounted thereon, and mounting protrusions 122 with a cross-sectional shape of “┘” are formed on one and the other sides of the bottom surface of the mounting groove 121 so that it can be inserted and mounted into the mounting portion 111 of the main body 110, and pressure fixing protrusions 123 are protrudingly formed on the inner surfaces facing each other of the mounting groove 121 so that the outer peripheral surface of the drug storage portion 11 of the drug sprayer 10 can be pressurized and fixed, and elastic holes 124 are formed by cutting from both sides of the pressure fixing protrusions 123 to the top surface so that the pressure fixing protrusions 123 can elastically pressurize and fix the outer peripheral surface of the drug storage portion 11.
[0032] The heat exchange member 130 described above is installed inside one side of the main body 110, and on the left and right sides of the one side, a coolant inlet 131 and an outlet 132 are formed to supply and circulate coolant through a coolant supply pipe and an outlet pipe in response to the control of the control unit, and to exchange heat with the thermoelectric element 140 in close contact with the contact portion 151 of the electrode plate 150.
[0033] That is, the heat exchange member 130 described above is installed inside one side of the main body 110, and has a cooling water inlet 131 and outlet 132 formed on the left and right sides of one side so that the cooling water circulated through a cooling water supply pipe and an outlet pipe piped to the other side of the main body 110 can exchange heat with the thermoelectric element 140 that is in close contact with the contact portion 151 of the electrode plate 150, and a fixing member 133 that can be fixed to the contact portion 151 of the electrode plate 150 through a plurality of fixing screws is formed on the left and right sides.
[0034] The thermoelectric element 140 described above has one side in close contact with the other side of the heat exchange member 130, and a thermoelectric element cable connected to a positive terminal and a negative terminal is wired to the other side of the main body so as to transmit cooling heat. The configuration of the thermoelectric element described above is well known, and therefore a detailed description thereof will be omitted.
[0035] The electrode plate 150 is electrically connected to a power supply cable to generate an electric pulse, and a portion of the electrode plate 150 is inserted into the inside of the front end of the main body 110, thereby making one side of the electrode plate 150 in close contact with the thermoelectric element 140. The electrode plate 150 is formed of a contact portion 151 fixed to the heat exchange member 130 through a plurality of fixing screws, and a contact portion 152 expanded from the other side of the contact portion 151 and exposed to the outside of the front end of the main body 110, thereby receiving the cooling heat supplied from the thermoelectric element 140 and cooling the skin surface.
[0036] Here, a fixing screw groove 151a is formed on both sides of the contact portion 151 so as to be fixed to the fixing hole 110a of the main body portion 110 via a plurality of fixing screws, and a locking groove 151a capable of locking the locking protrusion 112 of the main body portion 110 is formed on the bottom surface.
[0037] In addition, the contact portion 152 of the electrode plate 150 described above has a protrusion 152a protruding from one side of the outer periphery so that it can contact all parts of the skin around the eyes and nose to cool the skin and inject medicine, and the protrusion 152a has an injection hole 152b into which the injection port 11a of the medicine injector 10 can be inserted and engaged to inject medicine.
[0038] When using the one-handed operation-capable skin drug injection device according to the present invention to inject a drug into the skin of a patient, the practitioner holds the main body 110 in one hand and then rubs the contact portion 152 of the electrode plate 150 against the skin of the patient, as shown in the attached Figures 1 to 4.
[0039] As a result, a temporary hole is formed in the skin of the patient by the electrical pulse outputted through the electrode plate 150 .
[0040] Thereafter, the practitioner uses the thumb of the hand holding the main body 110 to press the pushing part 12 of the medicine injector 10 which is pressurized and fixed to the pressurizing and fixing protrusion 123 of the mounting member 120 .
[0041] By pressing the pushing part 12, the medicine stored in the medicine storage part 11 is injected onto the skin through the injection port 11a and the injection hole 152b of the contact part 152.
[0042] As described above, the drug injected into the skin is delivered into the skin tissue through the temporarily formed holes.
[0043] As described above, while the drug is being administered, the thermoelectric element 140 is cooled through the heat exchange member 130 .
[0044] The cooling heat generated by cooling the thermoelectric element 140 is transferred through the contact portion 151 of the electrode plate 150, so that the entire electrode plate 150 is cooled.
[0045] As a result, even if a strong electrical pulse is applied to the surface of the skin from the electrode plate 150, strong irritation and pain are not generated.
[0046] Meanwhile, when injecting a drug into the subject's skin as described above, in case of injecting a drug into the area around the eyes and nose, the area around the eyes and nose are rubbed with the protruding portion 152a of the contact portion 152 to form a temporary hole, and then the thumb is used to press the pushing portion 12 of the drug sprayer 10, so that the drug is introduced into the skin tissue through the temporary hole.
[0047] The one-handed skin drug injection device of the present invention configured as described above can be operated with one hand, as described above, and can inject drugs into the skin of the patient more quickly, and the protrusion 152a of the contact portion 152 makes it possible to care for the entire facial skin.
[0048] The above description is merely illustrative of the technical idea of the present invention, and various modifications and variations may be made by those skilled in the art without departing from the essential characteristics of the present invention. Therefore, the embodiments disclosed in the present invention are for the purpose of illustrating, not limiting, the technical idea of the present invention, and the scope of the technical idea of the present invention is not limited by such embodiments. The scope of protection of the present invention should be interpreted according to the claims below, and all technical ideas within the scope equivalent thereto should be interpreted as being included in the scope of the present invention. [Explanation of symbols]
[0049] 10 Drug Injector 100 Skin drug injection device 110 Main body 120 Mounting material 130 Heat exchange components 140 Thermoelectric element 150 Electrode plate
Claims
1. A main body (110) formed of a tube having a front end and a rear end penetrated therethrough; a mounting member (120) mounted on the body (110) and capable of elastically connecting and disconnecting the drug storage portion (11) of the drug sprayer (10); a heat exchange member (130) disposed inside the body (110) and having a cooling water inlet (131) and an outlet (132) formed on the left and right sides of one side thereof for supplying and circulating cooling water corresponding to the control of the control unit to perform heat exchange; a thermoelectric element (140) in which the one surface is in close contact with the other surface of the heat exchange member (130), the thermoelectric element (140) is connected to a positive terminal and a negative terminal so as to be capable of transmitting cooling heat, and a thermoelectric element cable is wired; an electrode plate (150) electrically connected to a power supply cable to generate an electric pulse, the one side of which is in close contact with the thermoelectric element (140) and formed with a contact portion (152) for receiving the cooling heat supplied from the thermoelectric element (140) and cooling the skin surface; A skin drug administration device capable of one-handed operation, comprising: The main body (110) is divided into two parts, which are joined together to form an installation space therein, and a mounting part (111) on the outer circumferential surface to which the mounting member (120) can be detached is formed, The electrode plate (150) is formed of a contact portion (151) fixed to the heat exchange member (130) so that one surface of the electrode plate (150) is in close contact with the thermoelectric element (140), and a contact portion (152) expanded from the other surface of the contact portion (151) and exposed to the outside of the front end of the body portion (110). A skin drug administration device that can be operated with one hand.
2. The one-handed drug injection device according to claim 1, characterized in that the mounting portion (111) of the main body portion (110) is composed of a pair of mounting grooves (111a) and a mounting protrusion (111b) having one end integrally connected to the outer circumferential surface of the main body portion (110) and the other end protruding upward to open a portion of the mounting groove (111a) and to attach and detach the mounting member (120).
3. The mounting member (120) has a laterally concave mounting groove (121) formed on its upper surface so that the drug storage portion (11) of the drug sprayer (10) can be mounted thereon, mounting protrusions (122) capable of being mounted on the mounting portion (111) of the main body portion (110) are formed on one side and the other side of the bottom surface of the mounting groove (121), a pressure fixing protrusion (123) protruding from the inner surface of the mounting groove (121) capable of pressurizing and fixing the outer circumferential surface of the drug storage portion (11) of the drug sprayer (10), and elastic holes (124) cut from both sides of the pressure fixing protrusion (123) to the upper surface are formed.
4. The one-handed drug injection device according to claim 1, characterized in that the mounting portion (151) has a fixing screw groove (151a) formed on both sides thereof for fixing to the main body portion (110), and a locking groove (151a) formed on the bottom thereof for locking the front end of the main body portion (110).
5. 5. The one-handed drug injection device according to claim 1, wherein the front end of the body portion (110) is further formed with a locking protrusion (112) bent inwardly to lock with the contact portion (151) of the electrode plate (150).
6. The contact portion (152) of the electrode plate (150) has a protrusion (152a) protruding from one side of the outer circumferential surface, and the protrusion (152a) has an injection hole (152b) into which the injection port (11a) of the drug injector (10) is inserted and engaged to enable injection of the drug.
Citation Information
Patent Citations
Device for dosing medicine through the skin
KR101052274B1