Radiation detection device, its operating method and operating program

Abstract

To provide a radiation detector capable of improving accuracy of offset correction and suppressing an influence of a residual image, and an operation method and an operation program thereof.SOLUTION: A radiation detector acquires an average offset image in a state that a radioactive ray is not radiated; acquires a first image when a first time elapses from the continuous radiation of a radioactive ray for imaging a subject in a pixel region; acquires a second image when a second time longer than the first image elapses from the end of the continuous radiation; radiates a radioactive ray for imaging the subject in the pixel region after the second time elapses from the end of the continuous radiation; acquires a radiation image by reading out a pixel signal from the pixel region; and generates an offset image indicating an offset component and a residual image indicating a residual image component according to the time of the continuous radiation, the first time, the second time, and a prescribed time on the basis of the first image, the second image, and the average offset image.SELECTED DRAWING: Figure 6

Description

[Technical Field]

[0001] The technology of the present disclosure relates to a radiation detection device, an operating method thereof, and an operating program thereof. [Background technology]

[0002] In the medical field, X-ray imaging systems that use radiation such as X-rays are known. X-ray imaging systems consist of an X-ray source that generates X-rays, an X-ray detector that detects X-ray images based on the X-rays that have passed through the subject, and a console that controls the drive of the X-ray image detector and stores and displays the X-ray images.

[0003] There are two types of X-ray detectors: a direct conversion type that converts X-rays directly into electric charges, and an indirect conversion type that converts X-rays into visible light and then converts the visible light into electric charges. In either type, the X-ray detector has a pixel area where multiple pixels that detect X-rays are arranged, and a readout unit that reads out pixel signals from the pixel area, and generates an X-ray image based on the pixel signals read out by the readout unit.

[0004] An X-ray image detected by an X-ray detector contains dark current noise generated in each pixel and fixed pattern noise generated by a charge amplifier or the like included in the readout unit. To remove such noise components from an X-ray image, offset data is acquired in advance prior to X-ray imaging. The offset data is acquired by reading pixel signals from a pixel region when no X-rays are irradiated. The offset data is data containing only noise components. After acquiring the offset data, offset correction is performed by subtracting the offset data from the X-ray image obtained by X-ray imaging, thereby obtaining an X-ray image from which noise has been removed. Various methods for performing such offset correction have been proposed (see, for example, Patent Document 1). Furthermore, to further improve the accuracy of offset correction, it has been proposed to acquire offset data multiple times and use the average value of multiple offset data obtained for offset correction. Averaging multiple offset data reduces random noise. [Prior art documents] [Patent documents]

[0005] [Patent Document 1] Japanese Patent Application Publication No. 2016-201634 Summary of the Invention [Problem to be solved by the invention]

[0006] Fluoroscopy is sometimes performed, in which X-rays are continuously irradiated onto a subject and the resulting fluoroscopic images are displayed in real time. Because X-rays are continuously irradiated onto the subject during fluoroscopy, offset data cannot be obtained. Furthermore, when imaging continues from a previous imaging session, the X-ray image contains noise due to residual images (lag) of the X-rays irradiated during the previous imaging session. Lag can occur in both direct and indirect conversion X-ray detectors. In the case of the indirect conversion system, lag occurs when the luminescence characteristics of the scintillator layer, which converts X-rays into visible light, change due to the high energy of the incident X-rays, causing the effects of the previous X-ray imaging to remain in the scintillator layer until the next X-ray imaging session.

[0007] The decay behavior of lag differs depending on the continuous X-ray irradiation time and the elapsed time since the end of continuous irradiation. Dark current is a noise component that occurs when no X-rays are irradiated, and is primarily caused by heat. However, the dark current also increases and decreases differently depending on the continuous X-ray irradiation time and the elapsed time since the end of continuous irradiation. Therefore, it is necessary to correct X-ray images by taking into account both the offset component, which is a noise component based on dark current, and the lag component, which is a noise component based on lag.

[0008] The present disclosure has been made in consideration of the above circumstances, and aims to improve the accuracy of offset correction and to suppress the influence of afterimages. [Means for solving the problem]

[0009] The radiation detection device according to the present disclosure includes: a pixel region in which a plurality of pixels for detecting radiation are arranged; a readout unit that reads out pixel signals from the pixel region; at least one processor; The processor acquiring an average offset image by averaging a plurality of images acquired by reading pixel signals from the pixel region a plurality of times in a state where no radiation is irradiated; continuously irradiating the pixel region with radiation for photographing the subject, and reading out pixel signals from the pixel region when a first time has elapsed since the end of the continuous irradiation to obtain a first image; a second image is acquired by reading out pixel signals from the pixel region when a second time period longer than the first time period has elapsed since the end of the continuous irradiation; After a specified time has elapsed since the end of the continuous irradiation, the pixel area is irradiated with radiation for photographing the subject, and pixel signals are read out from the pixel area to obtain a radiation image; Based on the first image, the second image, and the average offset image, an offset image representing an offset component according to the time of continuous irradiation, the first time, the second time, and the specified time, and an afterimage image representing an afterimage component are generated.

[0010] In the radiation detection device according to the present disclosure, the processor repeatedly reads out pixel signals from the pixel region after acquiring the first image to update the second image; Based on the first image, the updated second image, and the average offset image, an offset image and a residual image are generated according to the time of continuous irradiation, the first time, the updated second time from the end of continuous irradiation to the acquisition of the updated second image, and a specified time.

[0011] Furthermore, in the radiation detection device according to the present disclosure, the processor may continue updating the second image until a third time longer than the second time has elapsed since the end of the continuous irradiation, stop updating the second image after the third time has elapsed until a fourth time longer than the third time has elapsed, resume updating the second image after the fourth time has elapsed, update the second image until a fifth time longer than the fourth time has elapsed, and stop acquiring the second image and update the average offset image after the fifth time has elapsed.

[0012] Furthermore, in the radiation detection device according to the present disclosure, when the specified time is equal to or shorter than a fourth time, the processor generates an offset image and a residual image according to the time of continuous irradiation, the first time, the second time, and the specified time based on the first image, the second image, and the average offset image; If the specified time is greater than the fourth time and is equal to or less than the fifth time, an offset image may be generated based on the second image and the average offset image.

[0013] In the radiation detection device according to the present disclosure, if the specified time is equal to or shorter than a fourth time, the processor corrects the radiographic image based on the average offset image, the offset image, and the residual image to generate a corrected radiographic image. if the specified time is greater than the fourth time and less than or equal to the fifth time, correcting the radiographic image based on the average offset image and the residual image to generate a corrected radiographic image; If the specified time exceeds the fifth time, the radiographic image may be corrected based on the average offset image to generate a corrected radiographic image.

[0014] In the radiological image detecting device according to the present disclosure, the processor may output the corrected radiological image for display.

[0015] In addition, in the radiation detection device according to the present disclosure, when a plurality of readout modes are set, which have different readout rates of pixel signals and different readout methods of pixel signals from pixel regions, The processor switches between the plurality of readout modes and successively acquires average offset images corresponding to each of the plurality of readout modes; successively acquiring first images corresponding to each of the plurality of readout modes while switching between the plurality of readout modes; After the first image is acquired, the second image corresponding to each of the plurality of readout modes may be updated while switching between the plurality of readout modes.

[0016] In addition, in the radiation detection device according to the present disclosure, the processor may continuously acquire the first image while switching among the multiple readout modes in order from the readout mode used during the previous radiation irradiation.

[0017] In the radiation detection device according to the present disclosure, the processor may acquire the first image and the second image using pixel signals other than the pixel signals read out from the pixel region when switching the readout mode.

[0018] In addition, in the radiation detection device according to the present disclosure, the processor reads out pixel signals from the pixel region a plurality of first times around a first time, and averages the pixel signals read out the first times to obtain a first image; The pixel signals may be read from the pixel region a second number of times, greater than the first number of times, around the second time period, and the pixel signals read the second number of times may be averaged to obtain the second image.

[0019] The method for operating a radiation detection device according to the present disclosure includes: a pixel area in which a plurality of pixels for detecting radiation are arranged; A method for operating a radiation detection device including a readout unit that reads out pixel signals from a pixel region, the method comprising: acquiring an average offset image by averaging a plurality of images acquired by reading pixel signals from the pixel region a plurality of times in a state where no radiation is irradiated; continuously irradiating the pixel region with radiation for photographing the subject, and reading out pixel signals from the pixel region when a first time has elapsed since the end of the continuous irradiation to obtain a first image; a second image is acquired by reading out pixel signals from the pixel region when a second time period longer than the first time period has elapsed since the end of the continuous irradiation; After a specified time has elapsed since the end of the continuous irradiation, the pixel area is irradiated with radiation for photographing the subject, and pixel signals are read out from the pixel area to obtain a radiation image; Based on the first image, the second image, and the average offset image, an offset image representing an offset component according to the time of continuous irradiation, the first time, the second time, and the specified time, and an afterimage image representing an afterimage component are generated.

[0020] The operation program for the radiation detection device according to the present disclosure includes: a pixel area in which a plurality of pixels for detecting radiation are arranged; a readout unit that reads out pixel signals from the pixel region, a step of averaging a plurality of images acquired by reading pixel signals from the pixel region a plurality of times in a state where no radiation is irradiated, to acquire an average offset image; a step of continuously irradiating a pixel region with radiation for photographing a subject, and reading out pixel signals from the pixel region when a first time has elapsed since the end of the continuous irradiation, thereby acquiring a first image; a step of reading out pixel signals from the pixel region to acquire a second image when a second time period longer than the first time period has elapsed since the end of the continuous irradiation; a step of irradiating the pixel area with radiation for photographing the subject after a specified time has elapsed since the end of the continuous irradiation, and reading out pixel signals from the pixel area to obtain a radiological image; The computer is caused to execute a procedure of generating an offset image representing an offset component corresponding to the time of continuous irradiation, the first time, the second time, and the specified time, and an afterimage image representing an afterimage component, based on the first image, the second image, and the average offset image. [Effects of the Invention]

[0021] According to the technology of the present disclosure, it is possible to improve the accuracy of offset correction and suppress the influence of image lag. [Brief explanation of the drawings]

[0022] [Figure 1] Schematic diagram showing the configuration of an X-ray imaging system [Figure 2] Diagram showing an X-ray fluoroscopy device equipped with a C-arm [Figure 3] Perspective view of an electronic cassette [Figure 4] Schematic diagram showing the configuration of the image detection unit [Figure 5] Block diagram showing the configuration of the control unit of the image detection unit [Figure 6] Block diagram showing the functional configuration of the control unit [Figure 7] FIG. 10 is a diagram for explaining the processing performed by the control unit when acquiring an image for correcting an X-ray image. [Figure 8] Diagram to explain lag [Figure 9] A diagram for explaining the reading of pixel signals after continuous X-ray irradiation. [Figure 10] A graph showing the relationship between the time elapsed from the end of irradiation and the error in the amount of lag depending on the number of frames used for averaging. [Figure 11] A diagram to explain X-ray irradiation, X-ray image acquisition, and correction according to the elapsed time since the end of continuous X-ray irradiation. [Figure 12] Flowchart showing the process of generating an image for correcting an X-ray image [Figure 13] Flowchart showing the process of correcting an X-ray image [Figure 14] FIG. 10 is a diagram for explaining timing for acquiring a first image while switching between multiple readout modes. [Figure 15] FIG. 10 is a diagram for explaining the timing of acquiring a second image while switching between multiple readout modes. DETAILED DESCRIPTION OF THE INVENTION

[0023] Hereinafter, an embodiment of the present disclosure will be described with reference to the drawings. Fig. 1 is a schematic configuration diagram of an X-ray imaging system to which a radiation detection device according to an embodiment of the present disclosure is applied. As shown in Fig. 1, the X-ray imaging system 2 is composed of an X-ray irradiation device 2A and an X-ray imaging device 2B.

[0024] The X-ray irradiator 2A has an X-ray source 10, a radiation source control device 11, and an irradiation switch 12. The X-ray source 10 has an X-ray tube and an irradiation field limiter (collimator) that limits the irradiation field of X-rays emitted by the X-ray tube. The radiation source control device 11 controls the operation of the X-ray source 10. The irradiation switch 12 instructs the X-ray source 10 to start irradiating X-rays in response to an operation by an operator such as a radiologist. X-rays are an example of radiation in the present disclosure. Here, the X-ray imaging system 2 in this embodiment performs fluoroscopic imaging in which a subject is continuously irradiated with X-rays and X-ray images are sequentially acquired at a predetermined frame rate and readout method during the irradiation.

[0025] The X-ray imaging device 2B has an electronic cassette 13 and a console 14. The electronic cassette 13 is a portable X-ray detector. The console 14 controls the operation of the electronic cassette 13 and processes the display of X-ray images. The X-ray imaging system 2 is also provided with an upright imaging table 15 or a supine imaging table 16. The upright imaging table 15 is used when imaging a subject in an upright position. The supine imaging table 16 is used when imaging a subject in a supine position. The electronic cassette 13 is detachably set in a holder 15A of the upright imaging table 15 or a holder 16A of the supine imaging table 16. An X-ray image is an example of a radiation image in the present disclosure. The electronic cassette 13 is an example of a radiation detection device in the present disclosure.

[0026] The X-ray irradiator 2A and the X-ray imaging device 2B are not electrically connected. That is, the X-ray imaging device 2B is not a synchronous type in which the electronic cassette 13 operates in synchronization with the start of X-ray irradiation, but an asynchronous type. Therefore, the electronic cassette 13 is provided with an irradiation start detection function that detects when X-ray irradiation has started by the X-ray irradiator 2A.

[0027] The console 14 is connected to the electronic cassette 13 via a wired or wireless method so as to be able to communicate with the electronic cassette 13. The console 14 controls the operation of the electronic cassette 13 in response to input operations by an operator via an input device 14A such as a keyboard. X-ray images acquired by the electronic cassette 13 are output to the console 14 for display and are displayed on a display 14B provided on the console 14. The X-ray images are also stored in a storage device 14C such as a hard disk or flash memory built into the console 14, or in an image storage server (not shown) connected to the console 14 via a network.

[0028] As the X-ray imaging system according to this embodiment, an X-ray fluoroscopic imaging device equipped with a C-arm suitable for fluoroscopic imaging may be used. Fig. 2 is a diagram showing an X-ray fluoroscopic imaging device equipped with a C-arm. In Fig. 2, the same components as those in Fig. 1 are given the same reference numerals, and detailed descriptions thereof will be omitted.

[0029] The X-ray fluoroscopic imaging device 50 shown in Fig. 2 includes a C-arm 52. An imaging unit 53 is attached to one end of the C-arm 52, and an X-ray irradiation unit 54 is attached to the other end thereof so as to face the imaging unit 53. An electronic cassette 13 is housed inside the imaging unit 53. The X-ray irradiation unit 54 corresponds to the X-ray irradiation device 2A shown in Fig. 1, and houses an X-ray source 10 inside.

[0030] C-arm 52 is held by C-arm holder 57 so as to be movable in the direction of arrow A shown in Fig. 2, so that the angles of imaging unit 53 and X-ray irradiation unit 54 relative to the z direction (vertical direction) shown in Fig. 2 can be changed together. C-arm holder 57 also has shaft 58, which rotatably connects C-arm 52 to bearing 59. This allows C-arm 52 to rotate in the direction of arrow B shown in Fig. 2 around shaft 58 as the rotation axis.

[0031] The X-ray fluoroscopy apparatus 50 includes a main body 60. A plurality of wheels 61 are attached to the bottom of the main body 60, making the X-ray fluoroscopy apparatus 50 movable. A support shaft 62 that expands and contracts in the z-axis direction in FIG. 2 is provided at the top of the housing of the main body 60 in FIG. 2. A bearing 59 is held at the top of the support shaft 62 so that it can move in the direction of arrow C. A control unit 70 corresponding to the console 14 is housed inside the main body 60. An input device 14A and a display 14B are also provided at the top of the main body 60.

[0032] With the above-described configuration, the X-ray fluoroscopy apparatus 50 irradiates radiation onto the subject H lying supine on the imaging table 64 from below, and the radiation that has passed through the subject H is detected by the electronic cassette 13 of the imaging unit 53 to obtain an X-ray image of the subject H. Here, the C-arm 52 is movable in the directions of arrows A, B, and C, and the X-ray fluoroscopy apparatus 50 is movable on wheels 61. Therefore, the X-ray fluoroscopy apparatus 50 shown in FIG. 2 can image a desired part of the subject H lying supine on the imaging table 64 from a desired direction.

[0033] Fig. 3 is a perspective view of the electronic cassette. As shown in Fig. 3, the electronic cassette 13 is composed of an image detection unit 20 and a housing 13A. The housing 13A has a flat box shape and houses the image detection unit 20 therein. The housing 13A has a built-in battery (e.g., a secondary battery) that supplies power to drive the electronic cassette 13, and an antenna for wireless communication with the console 14.

[0034] 4 is a schematic diagram showing the configuration of the image detection unit 20. As shown in FIG. 4, the image detection unit 20 is made up of a pixel region 21, a readout circuit 22, a control unit 23, and a communication interface (I / F) 24.

[0035] The pixel region 21 is formed on a TFT (Thin Film Transistor) active matrix substrate. It has a plurality of pixels arranged in a matrix along the X and Y directions, which are orthogonal to each other. The pixels are elements that generate and store electric charges according to the amount of incident X-rays.

[0036] The image detection unit 20 can repeatedly record and read out X-ray images, and may be a so-called direct type that directly converts X-rays into electric charges, or a so-called indirect type that first converts X-rays into visible light and then converts the visible light into electric charge signals. Furthermore, the so-called TFT readout method is used as the readout method for radiation image signals, in which image signals are read out by turning TFT switches on and off.

[0037] The readout circuit 22 reads out the charge accumulated in each pixel of the pixel region 21 at a predetermined readout rate and readout method. The readout rate depends on the frame rate of the X-ray image, and values ​​such as 7.5 fps, 15 fps, and 30 fps are used. The readout method may be a method of reading out a pixel signal from each pixel, or a binning readout method of adding up and reading out the charge accumulated in multiple pixels. Hereinafter, the readout rate and readout method will be referred to as a readout mode.

[0038] The readout circuit 22 includes a charge amplifier that converts charge signals read out from the pixel region 21 into voltage signals, a correlated double sampling circuit that samples the voltage signals output from the charge amplifier, and an AD (Analog-to-Digital) conversion unit that converts the voltage signals into digital signals. The readout circuit 22 outputs pixel signals read out from each pixel in the pixel region 21 to the control unit 23. The pixel signals correspond to the amount of incident X-rays read out from the pixel region 21. One frame's worth of pixel signals read out from each pixel in the pixel region 21 constitute an X-ray image. The readout circuit 22 is an example of a readout unit in the present disclosure.

[0039] The control unit 23 performs X-ray imaging processing by controlling the readout operation of the readout circuit 22 to read out pixel signals from the pixel region 21, and also performs X-ray image acquisition processing based on the readout pixel signals. The control unit 23 also performs image acquisition processing to acquire an image for correcting the X-ray image, and correction processing to correct the X-ray image based on the acquired image.

[0040] The communication I / F 24 is connected to the console 14 (see FIG. 1) by wire or wirelessly, and transmits and receives data to and from the console 14. The communication I / F 24 receives data including imaging conditions transmitted from the console 14, and transmits data representing X-ray images generated by the control unit 23 to the console 14, etc.

[0041] FIG. 5 is a schematic block diagram showing the configuration of the control unit of the image detection unit. As shown in FIG. 5, the control unit 23 is composed of, for example, a CPU (Central Processing Unit) 30, a storage 31, a memory 32, and a timer 33. The storage 31 stores an operating program 34 and various data. The storage 31 is a non-volatile storage device such as a flash memory. The memory 32 is a volatile storage device such as a DRAM (Random Access Memory) and is used as a work memory. The timer 33 is a timing device that measures time such as irradiation time and timing of pixel signal readout. The CPU 30 operates each unit based on the operating program 34 to realize various functions. The CPU 30 is an example of a processor of the present disclosure.

[0042] Fig. 6 is a block diagram showing the functional configuration of the control unit. As shown in Fig. 6, the control unit 23 includes an X-ray image acquisition unit 40, a first acquisition unit 41, a second acquisition unit 42, and a correction unit 43. When the CPU 30 executes the operating program 34, the CPU 30 functions as the X-ray image acquisition unit 40, the first acquisition unit 41, the second acquisition unit 42, and the correction unit 43.

[0043] The X-ray image acquisition unit 40 operates during X-ray imaging, which is performed while X-rays are being irradiated. When X-rays generated by the X-ray source 10 are irradiated onto the pixel region 21 through the subject, the X-ray image acquisition unit 40 drives the readout circuit 22 to read out pixel signals from the pixel region 21 in accordance with a predetermined readout mode. The X-ray image acquisition unit 40 then generates an X-ray image X0 based on the readout pixel signals. The generated X-ray image X0 is stored in the memory 32. In this embodiment, the X-ray image acquisition unit 40 acquires the X-ray image X0 as a moving image by reading out pixel signals from the pixel region 21 in a predetermined readout mode while the exposure switch 12 is continuously pressed and X-rays are being continuously irradiated.

[0044] The first acquisition unit 41 and the second acquisition unit 42 perform processing to generate an image for correcting the X-ray image X0. FIG. 7 is a diagram for explaining processing performed by the control unit when acquiring an image for correcting the X-ray image. As shown in FIG. 7, before irradiating the electronic cassette 13 with X-rays to acquire the X-ray image X0, the first acquisition unit 41 repeatedly reads out pixel signals from the pixel region 21 multiple times in a predetermined readout mode by driving the readout circuit 22 while the pixel region 21 is not being irradiated with X-rays. Note that in FIG. 7, the readout timing is indicated by a line extending vertically. The number of readouts may be, for example, 64 times, but is not limited to this. Furthermore, the first acquisition unit 41 and the second acquisition unit 42 constantly read out pixel signals from the pixel region 21 in the readout mode while generating an image for correcting the X-ray image.

[0045] The first acquisition unit 41 then averages the read pixel signals and acquires an average offset image H0 based on the averaged pixel signals. The average offset image H0 represents noise components, i.e., offset components, consisting of dark current noise generated in each pixel of the pixel region 21 and fixed pattern noise generated by the charge amplifier and the like included in the readout circuit 22. The average offset image H0 is stored in the memory 32. The first acquisition unit 41 generates the average offset image H0 after a sufficient amount of time, for example, 180 seconds or more, has elapsed since the end of X-ray irradiation of the pixel region 21.

[0046] After the first acquisition unit 41 acquires the average offset image H0, the electronic cassette 13 is continuously irradiated with X-rays to acquire an X-ray image of the subject. The time period for continuous irradiation is designated as ts. Note that this embodiment relates to the process of correcting the X-ray image acquired by imaging performed after this continuous irradiation, and therefore, the correction of the X-ray image during this continuous irradiation will not be described.

[0047] Here, after the continuous irradiation of X-rays has ended, the pixel signal read out from pixel region 21 contains an afterimage (lag) due to the continuous irradiation of X-rays. Figure 8 is a diagram for explaining the lag. As shown in Figure 8, while pixel region 21 is being irradiated with X-rays, pixel signals having magnitudes according to the X-ray dose are obtained from pixel region 21. On the other hand, even when the irradiation of X-rays is stopped, the pixel signals obtained from pixel region 21 do not immediately become 0, and contain lag. As shown in Figure 8, the lag decreases over time. The decrease in lag is exponential, with the degree of attenuation being greater immediately after irradiation has stopped.

[0048] The second acquisition unit 42 drives the readout circuit 22 in a state where the pixel region 21 is not irradiated with X-rays when the first time t1 has elapsed after the continuous irradiation of X-rays ends, and reads out pixel signals from the pixel region 21 in a predetermined readout mode to acquire a first image H1. The first time t1 and a second time t2 described later are measured by the timer 33. In the following description, the first time t1 and the second time t2 are described with the time when the continuous irradiation of X-rays ends as the starting point of the start time. The same applies to a third time t3, a fourth time t4, and a fifth time t5 described later. Also, the relationship between the first to fifth times t1 to t5 is t1 < t2 < t3 < t4 < t5. FIG. 9 is a diagram for explaining the readout of pixel signals after continuous irradiation of X-rays. As shown in FIG. 9, the second acquisition unit 42 reads out pixel signals for five times before and after the first time t1 after the continuous irradiation of X-rays ends from the pixel region 21.

[0049] That is, the second acquisition unit 42 reads out pixel signals for a total of five frames, namely, two frames immediately before the first time t1 elapses, one frame at the first time t1, and two frames immediately after the first time t1 elapses, from the pixel region 21. In FIG. 9, the timing of the readout is also shown by line segments extending in the vertical direction. Then, the second acquisition unit 42 acquires the first image H1 by averaging the pixel signals for five times. By averaging the pixel signals in this way, the granular component in the first image H1 can be reduced. The first image H1 represents the lag component and the offset component included in the pixel signal at the time when the first time t1 has elapsed after the X-ray irradiation ends. The first image H1 and the first time t1 are stored in the memory 32.

[0050] Furthermore, when a second time (t2_1) has elapsed since the end of the continuous X-ray irradiation, the second acquisition unit 42 drives the readout circuit 22 in a state where the pixel region 21 is not irradiated with X-rays, thereby reading out pixel signals from the pixel region 21 in a predetermined readout mode to acquire a second image. Furthermore, when the second times t2_2, t2_3, ... have elapsed, the second acquisition unit 42 drives the readout circuit 22 in a state where the pixel region 21 is not irradiated with X-rays, thereby repeatedly reading out pixel signals from the pixel region 21 in a predetermined readout mode to update the second image. The interval between the second times t2_1, t2_2, t2_3, ... may be the same as the time from the end of the continuous X-ray irradiation until the second time t2_1 has elapsed. Note that, when t1 <t2<t3であることから、t1<t2_1,t2_2,t2_3…<t3である。

[0051] In this embodiment, the second acquisition unit 42 reads out pixel signals for 17 times at and before and after the second time t2 after the end of the continuous X-ray irradiation from the pixel region 21. That is, the second acquisition unit 42 reads out pixel signals for a total of 17 frames from the pixel region 21, including 8 frames immediately before the second times t2_1, t2_2, t2_3, ... have elapsed since the end of the continuous X-ray irradiation, 1 frame at the second times t2_1, t2_2, t2_3, ..., and 8 frames immediately after the second times t2_1, t2_2, t2_3, ... have elapsed. Note that FIG. 9 does not show all the readout timings for the second times t2_1, t2_2, t2_3, ....

[0052] The second acquisition unit 42 then averages the pixel signals from 17 times to acquire second images H2_1, H2_2, H2_3... corresponding to second times t2_1, t2_2, t2_3..., respectively. Averaging the pixel signals in this manner reduces the granular components in the second images H2_1, H2_2, H2_3.... The second images H2_1, H2_2, H2_3... represent the lag components and offset components contained in the pixel signals at the time points when second times t2_1, t2_2, t2_3... have elapsed since the end of X-ray irradiation. In this embodiment, the second images H2_1, H2_2, H2_3... are updated as described above, and the latest second image (simply referred to as H2) and the second time (referred to as t2) at which the latest second image was acquired are stored in the memory 32.

[0053] Figure 10 shows the relationship between the time elapsed since the end of irradiation and the lag error depending on the number of frames used for averaging when acquiring the first and second images. In Figure 10, the horizontal axis represents the time elapsed since X-ray irradiation, and the vertical axis represents the lag error, measured in units of QL (quantum level), which represents the amount of charge. Increasing the number of frames used for averaging can reduce the granular components contained in the pixel signal. However, because the amount of lag attenuation is large immediately after the end of X-ray irradiation, if the time elapsed since the end of continuous X-ray irradiation is short, the error between the averaged lag and the actual lag increases as the number of frames averaged increases.

[0054] For this reason, in this embodiment, the number of pixel signal frames when acquiring the first image H1 is reduced (5 frames), and the number of pixel signal frames when acquiring the second image H2 is increased (17 frames). Furthermore, the first time t1 is preferably the time immediately after the end of continuous X-ray irradiation, and is preferably within 4.5 seconds, more preferably within 2 seconds, and even more preferably 1.5 seconds. Furthermore, the second time t2_1 at which the second image H2_1 is acquired for the first time is preferably within 6 seconds after the end of continuous X-ray irradiation.

[0055] In this embodiment, the second acquisition unit 42 repeatedly updates the second image H2 until a third time t3, which is longer than the second time t2, has elapsed. After the third time t3 has elapsed, the second acquisition unit 42 stops updating the second image H2 until a fourth time t4, which is longer than the third time t3, has elapsed. After the fourth time t4 has elapsed, the second acquisition unit 42 resumes updating the second image H2 and continues updating the second image H2 until a fifth time t5, which is longer than the fourth time t4, has elapsed. After the fifth time t5 has elapsed, the second acquisition unit 42 stops acquiring the second image H2, and the first acquisition unit 41 updates the average offset image H0. Here, the third time t3 may be, for example, 30 seconds, the fourth time t4 may be, for example, 90 seconds, and the fifth time t5 may be, for example, 180 seconds.

[0056] When acquiring an X-ray image X0 by radiography, the correction unit 43 acquires from the memory 32 an image used to correct the X-ray image X0 in accordance with the elapsed time since the end of the previous continuous X-ray irradiation at the time of acquiring the X-ray image X0, and corrects the X-ray image X0 based on the acquired image. FIG. 11 is a diagram for explaining X-ray irradiation, acquisition of the X-ray image X0, and correction in accordance with the elapsed time since the end of the continuous X-ray irradiation. Note that in FIG. 11, the timing of acquisition of the X-ray image X0 is indicated by a line extending vertically. In this embodiment, as shown in FIG. 11, the second acquisition unit 42 acquires a first image H1 and a second image H2 during a period in which X-rays are not irradiated between the previous irradiation and the irradiation for acquiring the X-ray image X0 (referred to as the current irradiation). Then, when imaging for acquiring the X-ray image begins, the second acquisition unit 42 stops acquiring the first image H1 and the second image H2.

[0057] The correction unit 43 performs correction using the first pattern on X-ray images X0 acquired between the end of the previous continuous X-ray irradiation and a third time t3, which is longer than the second time t2. The correction unit 43 also performs correction using the first pattern on X-ray images X0 acquired between the end of the previous continuous X-ray irradiation and a fourth time t4, which is longer than the third time t3. The correction unit 43 also performs correction using the second pattern on X-ray images X0 acquired between the end of the previous continuous X-ray irradiation and a fifth time t5, which is longer than the fourth time t4. The correction unit 43 also performs correction using the third pattern on X-ray images X0 acquired after the fifth time t5 has elapsed since the end of the previous continuous X-ray irradiation. Correction using each pattern will be described below.

[0058] For the X-ray image X0 to be corrected, the correction unit 43 acquires the time ts of the previous continuous X-ray irradiation and the elapsed time since the end of the previous continuous X-ray irradiation when the X-ray image X0 to be corrected was acquired. For example, if the X-ray image to be corrected was acquired at the timing indicated by arrow A in FIG. 11, the correction unit 43 acquires the time td that has elapsed since the end of the previous continuous X-ray irradiation to the timing indicated by arrow A. The acquired elapsed time td is referred to as the specified time. The X-ray image X0 to be corrected is acquired when the specified time td has elapsed since the end of the previous continuous X-ray irradiation.

[0059] Therefore, for an X-ray image X0 acquired between the end of the previous continuous X-ray irradiation and a third time t3 that is longer than the second time t2, the specified time td is equal to or shorter than the third time t3. Furthermore, for an X-ray image X0 acquired between the end of the previous continuous X-ray irradiation and a fourth time t4 that is longer than the third time t3, the specified time td exceeds the third time t3 and is equal to or shorter than the fourth time t4. Furthermore, for an X-ray image X0 acquired between the end of the previous continuous X-ray irradiation and a fifth time t5 that is longer than the fourth time t4, the specified time td exceeds the fourth time t4 and is equal to or shorter than the fifth time t5. Furthermore, for an X-ray image X0 acquired after the end of the previous continuous X-ray irradiation and the fifth time t5, the specified time td exceeds the fifth time t5.

[0060] First, the first pattern will be described. When the specified time td is equal to or shorter than the fourth time t4, the correction unit 43 generates an offset image F1 representing an offset component and a lag image L1 representing a lag component according to the continuous X-ray irradiation time ts, the first time t1, the second time t2 when the latest second image H2 stored in the memory 32 was acquired, and the specified time td, based on the first image H1, the latest second image H2 stored in the memory 32, and the average offset image H0.

[0061] Specifically, when the specified time td is equal to or shorter than the fourth time t4, the correction unit 43 generates an offset image F1 and a lag image L1 according to the following equations (1) and (2) using the first image H1, the second image H2, and the average offset image H0, as well as two coefficients α1 and α2 corresponding to the continuous irradiation time ts, the first time t1, the second time t2, and the specified time td. Note that in equations (1) and (2), M[ ] indicates filtering using a median filter. The size of the median filter can be, for example, 19 × 19, but is not limited to this. Furthermore, equations (1) and (2) and equations (3) to (6) described below are calculations using images, but (x, y) representing pixel positions in the images are omitted.

[0062] F1=M[α2×H1+(1-α2)×H2-H0] (1) L1=M[-α1×(1-α2)×(H1-H2)] (2) In addition, in the formulas (1) and (2), α1=-(td / t1)^γ α2=-(t2 / t1)^γ / {1-(t2 / t1)^γ} where γ is a coefficient that determines the behavior of attenuation according to the previous continuous X-ray irradiation time ts. "^" represents exponentiation. In this embodiment, the relationship between the continuous X-ray irradiation time ts and the coefficient γ is stored in the memory 32 as a table, and the correction unit 43 refers to this table to obtain the coefficient γ according to the continuous X-ray irradiation time ts.

[0063] Then, the correction unit 43 corrects the X-ray image X0 using the following equation (3) to generate a corrected X-ray image X1. This makes it possible to remove the offset component and lag component contained in the X-ray image X0. Note that the offset image F1 and lag image L1 are generated by performing filtering processing using a median filter as shown in equations (1) and (2). Therefore, although the granularity is improved, the high-frequency components of noise generated on a pixel-by-pixel basis in the pixel region 21 are lost. Therefore, by generating a corrected X-ray image X1 using the average offset image H0 as shown in equation (3), it is possible to correct the high-frequency components of noise generated on a pixel-by-pixel basis in the pixel region 21. X1=X0-H0-F1-L1 (3)

[0064] Here, if the specified time td is equal to or shorter than the third time t3, the X-ray image X0 contains an offset component and a lag component. Therefore, by generating an offset image F1 and a lag image L1 from the first image H1 and the second image H2 using the above equations (1) to (3), the offset component and the lag component can be accurately separated from the X-ray image X0.

[0065] On the other hand, when the specified time td exceeds the third time t3, the lag component included in the X-ray image X0 decreases, and the offset component increases due to an increase in dark current noise caused by heat, making it impossible to accurately separate the offset component and lag component included in the X-ray image X0.

[0066] For this reason, in this embodiment, the second acquisition unit 42 stops updating the second image H2 when the third time t3 has passed since the previous continuous X-ray irradiation. On the other hand, the lag component included in the X-ray image X0 does not become 0. For this reason, in this embodiment, when the specified time td exceeds the third time t3 and is equal to or shorter than the fourth time t4, an offset image F1 and a lag image L1 are generated from the first image H1 and the second image H2 updated when the third time t3 has passed, using the above equations (1) to (3), and the offset component and lag component are separated from the X-ray image X0.

[0067] Note that even while updating of the second image H2 is stopped, pixel signals are read from the pixel region 21, which further increases dark current noise caused by heat, thereby reducing the accuracy of correction. For this reason, in this embodiment, when a fourth time t4 has elapsed since the end of the previous continuous X-ray irradiation, the second acquisition unit 42 resumes updating of the second image H2 and performs correction using a second pattern, which will be described later. The second image H2 acquired after updating is resumed will be dominated by the offset component.

[0068] Next, the second pattern will be described. When the specified time td is equal to or shorter than a fifth time t5 that is longer than the fourth time t4, the correction unit 43 generates an offset image F2 based on the most recent second image H2 and average offset image H0 stored in the memory 32. Specifically, the correction unit 43 generates the offset image F2 using the second image H2 and average offset image H0 according to the following equation (4). F2=M[H2-H0] (4)

[0069] Then, the correction unit 43 corrects the X-ray image X0 using the following equation (5) to generate a corrected X-ray image X1: The reason for using the average offset image H0 in equation (5) is the same as that for equation (3). X1=X0-H0-F2 (5)

[0070] When the specified time td passes a fourth time t4, the lag component included in the X-ray image X0 decreases, but the offset component increases due to an increase in dark current noise caused by heat. As a result, it becomes impossible to accurately separate the offset component and the lag component included in the X-ray image X0. For this reason, in this embodiment, when the specified time td passes the fourth time t4, an offset image F2 is obtained using only the second image H2 according to the second pattern, and the X-ray image X0 is corrected.

[0071] Next, the third pattern will be described. When the specified time td exceeds the fifth time t5, the lag component contained in the X-ray image X0 can be ignored, and the X-ray image X0 can be considered to contain only the offset component. Therefore, when the specified time exceeds the fifth time t5, the correction unit 43 corrects the X-ray image X0 based on the average offset image H0 using the following equation (6) to generate a corrected X-ray image X1. X1=X0-H0 (6)

[0072] Next, the processing performed in this embodiment will be described. First, the processing of acquiring an image for correcting an X-ray image will be described. Fig. 12 is a flowchart showing the processing of acquiring an image for correcting an X-ray image. When an instruction to start processing is given, the first acquisition unit 41 acquires an average offset image H0 in a state where X-rays are not irradiated onto the electronic cassette 13, and stores the image in the memory 32 (step ST1).

[0073] Next, when the irradiation switch 12 is pressed, X-rays are continuously irradiated onto the electronic cassette 13, and when the continuous irradiation is then terminated, the second acquisition unit 42 acquires a first image H1 in a state where the pixel region 21 is not irradiated with X-rays when a first time t1 has elapsed since the continuous irradiation of X-rays ended, and stores the first image H1 in the memory 32 (step ST2). Furthermore, when a second time t2 has elapsed since the continuous irradiation of X-rays ended, the second acquisition unit 42 acquires a second image H2 in a state where the pixel region 21 is not irradiated with X-rays, and stores the second image H2 in the memory 32 (step ST3).

[0074] Next, the second acquisition unit 42 determines whether the time since the end of the continuous X-ray irradiation has exceeded a third time t3 (step ST4). If step ST4 is negative, the process returns to step ST3, and the processes of steps ST3 and ST4 are repeated. As a result, the updated second image H2 is stored in the memory 32. If step ST4 is positive, the second acquisition unit 42 stops updating the second image H2 (step ST5).

[0075] Next, the second acquisition unit 42 determines whether the time since the end of the continuous X-ray irradiation has exceeded the fourth time t4 (step ST6). If the result of step ST6 is negative, the process returns to step ST5, and the processes of steps ST5 and ST6 are repeated. This keeps the updating of the second image H2 stopped. Therefore, the latest second image H2 stored in the memory 32 is the one acquired at the third time t3.

[0076] If step ST6 is positive, the second acquisition unit 42 resumes updating the second image H2, acquires the second image H2, and stores it in the memory 32 (step ST7). Subsequently, the second acquisition unit 42 determines whether the time since the end of the continuous X-ray irradiation has exceeded a fifth time t5 (step ST8). If step ST8 is negative, the process returns to step ST7, and the processes of steps ST7 and ST8 are repeated. As a result, the updated second image H2 is stored in the memory 32. If step ST8 is positive, the second acquisition unit 42 stops acquiring the second image H2, and the first acquisition unit 41 acquires the average offset image H0 (step ST9), thereby completing the process of acquiring images for correcting the X-ray image.

[0077] 12, when the capture of the X-ray image X0 is started, the second acquisition unit 42 stops the image acquisition process. As a result, the memory 32 stores the second image H2 acquired when the process was stopped.

[0078] Fig. 13 is a flowchart showing the process of correcting an X-ray image. Note that the X-ray image X0 is continuously acquired by the X-ray image acquisition unit 40 in a predetermined readout mode. The process shown in Fig. 13 starts when the process of acquiring the X-ray image X0 starts. The correction unit 43 acquires the previous continuous X-ray irradiation time ts for the X-ray image X0 to be corrected (step ST11), and acquires the elapsed time since the previous continuous X-ray irradiation ended when the X-ray image X0 was acquired, i.e., the specified time td (step ST12).

[0079] Then, the correction unit 43 determines whether the specified time td is equal to or shorter than the fourth time t4 (step ST13). If step ST13 is determined to be positive, the correction unit 43 generates an offset image F1 representing an offset component corresponding to the continuous X-ray irradiation time ts, the first time t1, the second time t2, and the specified time td and a lag image L1 representing a lag component based on the first image H1, the second image H2, and the average offset image H0 (step ST14). Then, the correction unit 43 corrects the X-ray image X0 using the first pattern to generate a corrected X-ray image X1 (step ST15). Next, the correction unit 43 determines whether an instruction to end the X-ray image acquisition process has been issued (step ST16). If step ST16 is determined to be negative, the correction unit 43 changes the X-ray image to be corrected to the next X-ray image (step ST17) and returns to the process of step ST12. If step ST16 is determined to be positive, the process ends.

[0080] On the other hand, if step ST13 is negative, the correction unit 43 determines whether the specified time td is equal to or less than the fifth time t5 (step ST18). If step ST18 is positive, the correction unit 43 generates an offset image F2 based on the second image H2 and the average offset image H0 (step ST19). Then, the correction unit 43 corrects the X-ray image X0 using the second pattern to generate a corrected X-ray image X1 (step ST20), and proceeds to the processing of step ST16.

[0081] If step ST18 is negative, the correction unit 43 corrects the X-ray image X0 using the third pattern based on the average offset image H0 to generate a corrected X-ray image X1 (step ST21), and proceeds to the processing of step ST16. If step ST16 is positive, the processing ends.

[0082] As a result, corrected X-ray images X1 are sequentially acquired, and the X-ray images X1 are displayed on the display 14B as moving images.

[0083] In this embodiment, the X-ray image X0 is corrected based on the first image H1, the second image H2, and the average offset image H0 in accordance with the continuous X-ray irradiation time ts, the first time t1, the second time t2, and the specified time td. This makes it possible to improve the accuracy of the offset correction and suppress the influence of an afterimage when correcting the X-ray image X0.

[0084] On the other hand, there are cases where a plurality of readout modes are switched between when reading out pixel signals from the pixel region 21. In this case, the first acquisition unit 41 may be configured to switch between the plurality of readout modes and continuously generate average offset images corresponding to each of the plurality of readout modes. Furthermore, the second acquisition unit 42 may be configured to switch between the plurality of readout modes and continuously acquire first images H1 corresponding to each of the plurality of readout modes.

[0085] 14 is a diagram illustrating the timing of acquiring a first image H1 while switching between multiple readout modes. As shown in FIG. 14, the second acquisition unit 42 first reads out five frames of pixel signals from the pixel region 21 in the first readout mode to acquire a first image H1p1 in the first readout mode. Next, the second acquisition unit 42 reads out five frames of pixel signals from the pixel region 21 in the second readout mode to acquire a first image H1p2 in the second readout mode. Furthermore, the second acquisition unit 42 reads out five frames of pixel signals from the pixel region 21 in the third readout mode to acquire a first image H1p3 in the third readout mode.

[0086] Here, since the readout mode has not been completely switched when the readout mode is switched, the readout rate and readout method are not stable. Therefore, the second acquisition unit 42 acquires the first images H1p1, H1p2, and H1p3 using pixel signals other than the pixel signals read from the pixel region 21 when the readout mode is switched. Specifically, as shown in FIG. 14, the first images H1p1, H1p2, and H1p3 are acquired without using the pixel signals for two frames acquired during the switch of the readout mode. This makes it possible to acquire the first images H1p1, H1p2, and H1p3 appropriate for the readout mode.

[0087] After acquiring the first image, the second acquisition unit 42 switches between multiple readout modes and repeatedly acquires consecutive second images corresponding to each of the multiple readout modes. FIG. 15 is a diagram illustrating the timing of acquiring the second image while switching between multiple readout modes. As shown in FIG. 15, the second acquisition unit 42 first reads out 17 frames of pixel signals from the pixel region 21 in the first readout mode to acquire a second image H2_1p1 in the first readout mode. Next, the second acquisition unit 42 reads out 17 frames of pixel signals from the pixel region 21 in the second readout mode to acquire a second image H2_1p2 in the second readout mode. Furthermore, the second acquisition unit 42 reads out 17 frames of pixel signals from the pixel region 21 in the third readout mode to acquire a second image H2_1p3 in the third readout mode.

[0088] Next, the second acquisition unit 42 reads out 17 frames of pixel signals from the pixel region 21 in the first readout mode to acquire a second image H2_2p1 in the first readout mode. Next, the second acquisition unit 42 reads out 17 frames of pixel signals from the pixel region 21 in the second readout mode to acquire a second image H2_2p2 in the second readout mode. Furthermore, the second acquisition unit 42 reads out 17 frames of pixel signals from the pixel region 21 in the third readout mode to acquire a second image H2_2p3 in the third readout mode. The second acquisition unit 42 repeats this type of reading to acquire second images corresponding to each of the multiple readout modes.

[0089] Here, when acquiring the second image, it is only necessary to acquire the second image using pixel signals other than the pixel signals read out from the pixel region 21 when switching the readout mode. Specifically, as shown in Fig. 15, the second image is acquired without using two frames of pixel signals acquired during switching of the readout mode. This makes it possible to acquire an appropriate second image according to the readout mode.

[0090] Here, when acquiring X-ray images, the same readout mode is often used consecutively, so when acquiring the first and second images using multiple readout modes, it is preferable that the readout mode used first is the readout mode used for the previous readout of pixel signals from the pixel region 21.

[0091] In the above embodiment, the second image H2 is updated, but the second image H2 may not be updated. In this case, the second image H2 acquired at the second time t2 is used to generate the offset image and the lag image, and to correct the X-ray image X0.

[0092] Furthermore, the radiation used in the above-described embodiment is not limited to X-rays, and the present invention can also be applied to a system that uses other radiation such as gamma rays to photograph a subject.

[0093] Furthermore, in the above embodiment, the following various processors can be used as the hardware structure of processing units that perform various processes, such as the X-ray image acquisition unit 40, the first acquisition unit 41, the second acquisition unit 42, and the correction unit 43. As described above, the various processors include a CPU, which is a general-purpose processor that executes software (programs) and functions as various processing units, as well as dedicated electrical circuits that are processors having a circuit configuration specifically designed to perform specific processes, such as a programmable logic device (PLD), which is a processor whose circuit configuration can be changed after manufacture, such as an FPGA (Field Programmable Gate Array), and an ASIC (Application Specific Integrated Circuit).

[0094] A single processing unit may be configured with one of these various processors, or may be configured with a combination of two or more processors of the same or different types (for example, a combination of multiple FPGAs or a combination of a CPU and an FPGA). Also, multiple processing units may be configured with a single processor.

[0095] Examples of configuring multiple processing units with a single processor include, first, a form in which one processor is configured with a combination of one or more CPUs and software, and this processor functions as multiple processing units, as typified by computers such as client and server. Second, a form in which a processor is used to realize the functions of an entire system including multiple processing units with a single IC (Integrated Circuit) chip, as typified by systems on chips (SoCs). In this way, various processing units are configured using one or more of the above-mentioned various processors as a hardware structure.

[0096] Furthermore, more specifically, the hardware structure of these various processors can be an electric circuit that combines circuit elements such as semiconductor elements. [Explanation of symbols]

[0097] 2 X-ray imaging system 2A X-ray irradiation device 2B X-ray equipment 10 X-ray source 11 Radiation source control device 12 Irradiation switch 13 Electronic cassette 13A housing 14 Console 14A Input Device 14B Display 14C Storage Device 15 Standing photography stand 15A holder 16 Recumbent photography stand 16A holder 20 Image detection unit 21 pixel area 22 Readout circuit 23 Control Unit 24 Communication Interface 30 CPU 31 Storage 32 memory 33 Timer 34 Operating Program 40 X-ray image acquisition section 41 First Acquisition Section 42 Second Acquisition Section 43 Correction unit 50 X-ray fluoroscopy equipment 52 C-arm 53 Photography Department 54 X-ray irradiation section 57 C-arm holder 58 Shaft 59 Bearings 60 Main body 61 wheels 62 Spindle 64 Camera stand 70 Control Unit H1, H1p1, H1p2, H1p3 First image H2_1p1, H2_1p2, H2_1p3, H2_2p1, H2_2p2, H2_2p3 Second image t1 first time t2, t2_1, t2_2, t2_3 Second time t3 Third Hour t4 The fourth hour t5 The fifth hour ts Irradiation time td specified time

Claims

1. a pixel area in which a plurality of pixels for detecting radiation are arranged; a readout unit that reads out pixel signals from the pixel region; at least one processor; The processor: acquiring an average offset image by averaging a plurality of images acquired by reading pixel signals from the pixel region a plurality of times in a state where the radiation is not irradiated; continuously irradiating the pixel region with the radiation for photographing the subject, and reading out pixel signals from the pixel region when a first time has elapsed since the continuous irradiation was completed to obtain a first image; a second image is acquired by reading out pixel signals from the pixel region when a second time period longer than the first time period has elapsed since the end of the continuous irradiation, and the second image is updated by repeatedly reading out pixel signals from the pixel region until a third time period longer than the second time period has elapsed, and after the third time period has elapsed, the updating of the second image is stopped until a fourth time period longer than the third time period has elapsed, and after the fourth time period has elapsed, the second image is updated until a fifth time period longer than the fourth time period has elapsed, and the time when the latest second image was acquired is set as an updated second time period, and after the fifth time period has elapsed, the acquisition of the second image is stopped and the average offset image is updated; and when the radiation for photographing a subject is irradiated onto the pixel region and pixel signals are read out from the pixel region to acquire a radiographic image during the period from the end of the continuous irradiation to the lapse of the fourth time period, a first offset image is generated based on the first image, the latest second image, and the average offset image, the first offset image representing an offset component corresponding to the time of the continuous irradiation, the first time period, the updated second time period, and a specified time period from the end of the continuous irradiation to the acquisition of the radiographic image, and a residual image is generated based on the first image and the latest second image, the first offset image representing an residual image component corresponding to the time of the continuous irradiation, the first time period, the updated second time period, and the specified time period; generating a corrected radiographic image by subtracting the average offset image, the first offset image, and the residual image from the radiographic image; When the radiation image is acquired during the period from the end of the continuous irradiation until the elapse of the fifth time after the fourth time has elapsed, a second offset image is generated based on the latest second image and the average offset image; A radiation detection device that generates a corrected radiation image by subtracting the average offset image and the second offset image from the radiation image.

2. The radiation detection device of claim 1, wherein when the radiation image is acquired after the fifth time has elapsed since the continuous irradiation was terminated, the processor generates a corrected radiation image by subtracting the average offset image from the radiation image.

3. The radiation detection apparatus according to claim 1 or 2, wherein the processor outputs the corrected radiation image for display.

4. When a plurality of readout modes are set, the readout modes have different readout rates of the pixel signals and different readout methods of the pixel signals from the pixel region, the processor successively acquires the average offset images corresponding to each of the plurality of readout modes while switching between the plurality of readout modes; successively acquiring the first images corresponding to each of the plurality of readout modes while switching between the plurality of readout modes; The radiation detection device according to claim 1 , wherein after the first image is acquired, the second image corresponding to each of the plurality of readout modes is updated while switching between the plurality of readout modes.

5. The radiation detection device according to claim 4 , wherein the processor continuously acquires the first images while switching among the plurality of readout modes in order from the readout mode used during the previous irradiation of the radiation.

6. The radiation detection device according to claim 4 , wherein the processor acquires the first image and the second image using pixel signals other than the pixel signals read out from the pixel region when the readout mode is switched.

7. the processor reads out the pixel signals from the pixel region a plurality of first times around the first time, and averages the pixel signals read out the first times to obtain the first image; 7. The radiation detection device according to claim 1, wherein the pixel signals are read out from the pixel region a second number of times before and after the second time period, the second number of times being greater than the first number of times, and the pixel signals read out the second number of times are averaged to acquire the second image.

8. a pixel area in which a plurality of pixels for detecting radiation are arranged; a readout unit that reads out pixel signals from the pixel region, acquiring an average offset image by averaging a plurality of images acquired by reading pixel signals from the pixel region a plurality of times in a state where the radiation is not irradiated; continuously irradiating the pixel region with the radiation for photographing the subject, and reading out pixel signals from the pixel region when a first time has elapsed since the continuous irradiation was completed to obtain a first image; a second image is acquired by reading out pixel signals from the pixel region when a second time period longer than the first time period has elapsed since the end of the continuous irradiation, and the second image is updated by repeatedly reading out pixel signals from the pixel region until a third time period longer than the second time period has elapsed, and after the third time period has elapsed, the updating of the second image is stopped until a fourth time period longer than the third time period has elapsed, and after the fourth time period has elapsed, the second image is updated until a fifth time period longer than the fourth time period has elapsed, and the time when the latest second image was acquired is set as an updated second time period, and after the fifth time period has elapsed, the acquisition of the second image is stopped and the average offset image is updated; and when the radiation for photographing a subject is irradiated onto the pixel region and pixel signals are read out from the pixel region to acquire a radiographic image during the period from the end of the continuous irradiation to the lapse of the fourth time period, a first offset image is generated based on the first image, the latest second image, and the average offset image, the first offset image representing an offset component corresponding to the time of the continuous irradiation, the first time period, the updated second time period, and a specified time period from the end of the continuous irradiation to the acquisition of the radiographic image, and a residual image is generated based on the first image and the latest second image, the first offset image representing an residual image component corresponding to the time of the continuous irradiation, the first time period, the updated second time period, and the specified time period; generating a corrected radiographic image by subtracting the average offset image, the first offset image, and the residual image from the radiographic image; When the radiation image is acquired during the period from the end of the continuous irradiation until the elapse of the fifth time after the fourth time has elapsed, a second offset image is generated based on the latest second image and the average offset image; The operational method generates a corrected radiographic image by subtracting the average offset image and the second offset image from the radiographic image.

9. a pixel area in which a plurality of pixels for detecting radiation are arranged; a readout unit that reads out pixel signals from the pixel region, a step of averaging a plurality of images acquired by reading pixel signals from the pixel region a plurality of times in a state where the radiation is not irradiated, to acquire an average offset image; a step of continuously irradiating the pixel region with the radiation for imaging a subject, and reading out pixel signals from the pixel region when a first time period has elapsed since the end of the continuous irradiation, thereby obtaining a first image; a step of reading out pixel signals from the pixel region to acquire a second image when a second time period longer than the first time period has elapsed since the end of the continuous irradiation, repeatedly reading out pixel signals from the pixel region until a third time period longer than the second time period has elapsed to update the second image, stopping updating of the second image after the third time period has elapsed until a fourth time period longer than the third time period has elapsed, updating the second image after the fourth time period has elapsed until a fifth time period longer than the fourth time period has elapsed, setting the time when the latest second image was acquired as an updated second time period, and stopping acquisition of the second image and updating the average offset image after the fifth time period has elapsed; a step of generating, when the pixel region is irradiated with the radiation for photographing a subject and pixel signals are read out from the pixel region to acquire a radiological image during the period from the end of the continuous irradiation to the lapse of the fourth time period, a first offset image representing an offset component corresponding to the time period of the continuous irradiation, the first time period, the updated second time period, and a specified time period from the end of the continuous irradiation to the acquisition of the radiological image, based on the first image, the latest second image, and the average offset image, and generating, based on the first image and the latest second image, an afterimage image representing an afterimage component corresponding to the time period of the continuous irradiation, the first time period, the updated second time period, and the specified time period; generating a corrected radiographic image by subtracting the average offset image, the first offset image, and the residual image from the radiographic image; generating a second offset image based on the latest second image and the average offset image when the radiation image is acquired during a period from the end of the continuous irradiation until the elapse of the fifth time after the fourth time has elapsed; and generating a corrected radiation image by subtracting the average offset image and the second offset image from the radiation image.

Images