Composite microneedle structures based on integrated circuit chips

Abstract

The present application provides a composite micro-needle structure based on an integrated circuit chip. The composite micro-needle structure based on the integrated circuit chip includes a micro-strip line, at least one micro-needle body, and at least one integrated circuit chip. The micro-needle body includes a hard needle and a soft needle. The soft needle is fixed to the upper surface of the hard needle via a fixing structural member. The integrated circuit chip is provided on the substrate of the micro-needle body. The integrated circuit chip is fixed to the soft needle of the micro-needle body to form an electrical connection. The micro-strip line is fixed to one end of the integrated circuit chip to form an electrical connection. The present application uses a hard needle to introduce the soft needle into the tissue, and then pulls out the hard needle, so that the soft needle and the hard needle can be well fixed, their relative movement can be prevented, and the disadvantages when only the hard needle or the soft needle is adopted can be avoided. In addition, by integrating the micro-needle body and the integrated circuit chip, on-site collection and stimulation of nerve signals can be realized, the functionality of the nerve interface can be optimized accordingly, and clinical needs can be better met.

Description

[Technical Field]

[0001] The present application is in the technical field of neural microelectrodes for brain-machine interfaces, and in particular relates to composite microneedle structures based on integrated circuit chips. [Background technology]

[0002] In neural interfaces, brain signals are collected through electrodes. Electrodes include invasive and non-invasive types, with brain signals collected by invasive electrodes being more accurate and reliable. Most conventional invasive microneedle structures are single-type electrodes, such as hard-needle Michigan electrodes, Utah electrodes, and soft-needle polyimide electrodes. However, hard needles (rigid needles) are unable to adaptively deform with the expansion and contraction of blood vessels during implantation, potentially causing tissue damage. On the other hand, soft needle structures are prone to deformation during implantation, require external device assistance, and have problems such as complex structure and low efficiency. Currently, both hard and soft needles have a relatively single function: they only have a recording function and do not have a stimulation effect. More importantly, the amplitude and frequency range of brain electrical signals are small, making them susceptible to noise interference, resulting in inaccurate extraction of brain electrical signals using conventional techniques. Summary of the Invention [Problem to be solved by the invention]

[0003] The object of the present application is to provide a composite microneedle structure based on an integrated circuit chip that can overcome at least some of the drawbacks present in the prior art. [Means for solving the problem]

[0004] To achieve the above object, the present invention employs the following technical solutions.

[0005] The composite microneedle structure based on an integrated circuit chip includes a microstrip line, at least one microneedle body, and at least one integrated circuit chip, wherein the microneedle body includes a hard needle and a soft needle, the soft needle is fixed to the upper surface of the hard needle via a fixing structural member, the integrated circuit chip is provided on the base of the microneedle body, the integrated circuit chip is fixed to the soft needle of the microneedle body to form an electrical connection, and the microstrip line is fixed to one end of the integrated circuit chip to form an electrical connection.

[0006] Furthermore, the hard needle has a hard needle base and at least one hard needle bioelectrode formed on the hard needle base, and the soft needle has a soft needle base and at least one soft needle bioelectrode formed on the soft needle base, the soft needle base being fixed to the hard needle base, and the soft needle bioelectrode being fixed to the hard needle bioelectrode.

[0007] Furthermore, the fixing structural member includes a first fixing member used to fix the soft needle bioelectrode and the hard needle bioelectrode, and a second fixing member used to fix the soft needle base and the hard needle base.

[0008] Furthermore, the first fixing member is a plurality of hook structures spaced apart along the length of the hard needle bioelectrode, the hook structures having a first part and a second part, the second part having both ends connected to the first part and the surface of the hard needle bioelectrode, respectively, the first part and the surface of the hard needle bioelectrode being parallel, the soft needle bioelectrode being located between the first part and the surface of the hard needle bioelectrode, and the second part and the surface of the hard needle bioelectrode forming a predetermined angle.

[0009] Furthermore, the preset angle between the second portion of the hook structure and the hard-needle bioelectrode is an acute angle.

[0010] Furthermore, the soft needle bioelectrode has an opening at a position corresponding to the hook structure through which the hook structure passes, and the opening has a hook detachment structure that allows the hook structure to detach from the soft needle, and the first part and second part of the hook structure and the surface of the hard needle bioelectrode form a slot, the slot facing toward the tip of the hard needle, and the hook detachment structure is provided at the end of the soft needle 11 away from the tip.

[0011] Furthermore, the hook release structure is a hook release portion extending from an edge of the opening toward inside the opening, the spacing between the hook release portions is smaller than the width of the second portion of the hook structure, the hook release portions are arranged symmetrically about the axis of the opening, and there is a gap between the side edge of the hook release portion and the corresponding side edge of the opening.

[0012] Furthermore, the second fixing member is a plurality of pin structures arranged on the hard needle base at intervals in the width direction of the hard needle, the pin structure being composed of a large-diameter upper cylinder and a small-diameter lower cylinder on the same axis, the soft needle base having pin holes formed at positions corresponding to the pin structures, the soft needle base having a plurality of centrally symmetrical patterns on the outside along the edges of the pin holes, and the diameter of the upper cylinder of the pin structure being larger than the diameter of the pin holes.

[0013] Furthermore, the connection position between the soft needle base and the integrated circuit chip is located between the second fixing member and the soft needle bioelectrode.

[0014] Furthermore, the integrated circuit chip includes a soft needle connection portion used to connect with the soft needle, and a microstrip line connection portion located on one side of the soft needle connection portion and used to connect with a microstrip line, the integrated circuit chip and the soft needle of the microneedle body are electrically connected by a flip chip method, and the microstrip line and the integrated circuit chip are electrically connected by a flip chip method; Compared with the prior art, the beneficial effects of the present invention are as follows:

[0015] (1) The composite microneedle structure based on the integrated circuit chip provided by the present application directly integrates the microneedle body with the integrated circuit chip, thereby realizing real-time, rapid and accurate extraction and stimulation of neural signals, and maximally reducing transmission loss and noise signals, thereby ensuring stable and loss-free signal transmission.

[0016] (2) The composite microneedle structure based on an integrated circuit chip as provided by the present application avoids the drawbacks of using only hard or soft needles by using a hard needle to introduce a soft needle into tissue and then withdrawing the hard needle.

[0017] (3) According to the composite microneedle structure based on the integrated circuit chip provided by the present application, by patterning a hook detachment structure on the soft needle bioelectrode of the soft needle and growing a hook structure at the corresponding position of the hard needle, the soft needle can be introduced and implanted using the hook structure, while the hard needle and the soft needle can be well fixed to prevent movement between them and reduce the risk of warping of the soft needle.

[0018] (4) According to the composite microneedle structure based on the integrated circuit chip provided by the present application, by patterning a centrally symmetrical pattern on the substrate of the soft needle and growing a pin structure at the corresponding position of the hard needle, the hard needle and the soft needle can be well fixed, preventing movement between them, and ensuring the stability and accuracy of implanting the soft needle.

[0019] The present application will now be explained in more detail with reference to the drawings. [Brief explanation of the drawings]

[0020] [Figure 1] 1 is a schematic diagram of a composite microneedle structure based on the integrated circuit chip of the present application. [Figure 2] FIG. 1 is a structural schematic diagram of a microneedle body according to the composite microneedle structure of the present application. [Figure 3] 1 is a schematic diagram of a fixing structure of a hard needle bioelectrode and a soft needle bioelectrode according to the composite microneedle structure of the present application. FIG. [Figure 4] FIG. 1 is a structural schematic diagram of a hard needle bioelectrode according to the composite microneedle structure of the present application. [Figure 5] FIG. 1 is a structural schematic diagram of a soft needle bioelectrode according to the present invention having a composite microneedle structure. [Figure 6] FIG. 1 is a schematic diagram of the fixing structure of a hard needle substrate and a soft needle substrate in the composite microneedle structure of the present application. [Figure 7] FIG. 1 is a structural schematic diagram of a hard needle substrate according to the composite microneedle structure of the present application. [Figure 8] FIG. 1 is a structural schematic diagram of a soft needle substrate according to the composite microneedle structure of the present application. [Figure 9] 1 is a schematic diagram of the connection between a microstrip line and an integrated circuit chip in the composite microneedle structure of the present application. [Figure 10] FIG. 1 is a schematic diagram of the connection between the microneedle body and the integrated circuit chip in the composite microneedle structure of the present application. DETAILED DESCRIPTION OF THE INVENTION

[0021] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in combination with the accompanying drawings in the embodiments of the present invention. It is clear that the described embodiments are only some of the embodiments of the present invention, and not all of the embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments that a person skilled in the art can obtain without creative work fall within the scope of protection of the present invention.

[0022] In the description of this application, the orientations or positional relationships indicated by terms such as "center," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," and "outer" are orientations or positional relationships shown based on the drawings, and are intended solely for the convenience and simplification of the description of this application. It should be understood that these terms do not suggest or imply that the devices or elements they refer to must necessarily have a specific orientation or be constructed or operated in a specific orientation, and therefore should not be understood as limitations on this application.

[0023] It should be noted that in the description of this application, unless otherwise clearly specified or limited, the terms "installed," "connected," and "connected" should be understood in a broad sense. For example, they may refer to a fixed connection, a detachable connection, an abutting connection, or an integral connection. Those skilled in the art can understand the specific meaning of the above terms in the present invention based on specific circumstances.

[0024] The terms "first" and "second" are used for descriptive purposes only and should not be understood to indicate or imply relative importance or to implicitly designate the number of technical features presented. Thus, a feature qualified by "first" or "second" may explicitly or implicitly include one or more of the feature. In the present description, unless otherwise qualified, "plurality" means two or more than two.

[0025] As shown in FIGS. 1 and 2 , this embodiment provides a composite microneedle structure based on an integrated circuit chip. The composite microneedle structure based on an integrated circuit chip includes a microstrip line 1, at least one microneedle body, and at least one integrated circuit chip 2. The microneedle body includes a hard needle 3 and a soft needle 4. The soft needle 4 is fixed to the upper surface of the hard needle 3 via a fixing structure. The integrated circuit chip 2 is mounted on the base of the microneedle body, and the integrated circuit chip 2 is fixed to the soft needle 4 of the microneedle body to form an electrical connection. The microstrip line 1 is fixed to one end of the integrated circuit chip 2 to form an electrical connection. The hard needle 3 has a certain rigidity and can be implanted in the soft tissue of a human or animal. For example, the hard needle 3 can be made of a silicon material. The soft needle 4 has a certain flexibility. For example, the soft needle 4 can be made of silicon nitride, polysilicon, silicon carbide, or other materials. In this embodiment, since the hard needle 3 has a certain rigidity, by placing the soft needle 4 flat on top of the hard needle 3, the hard needle 3 can move and be implanted into the soft tissue of a human or animal. After the soft needle 4 is implanted into the tissue, the hard needle 3 is pulled out, separating the hard needle 3 from the soft needle 4, leaving the soft needle 11 in the implanted tissue, effectively avoiding the drawbacks of using only a hard needle or a soft needle. Furthermore, by integrating the microneedle body with the integrated circuit chip 2, on-site collection and stimulation of neural signals can be realized, thereby optimizing the functionality of the neural interface and better meeting clinical needs.

[0026] 2, 3, and 6, the hard needle 3 has a hard needle base 16 and at least one hard needle bioelectrode 11 formed on the hard needle base 16, and the soft needle 4 has a soft needle base 17 and at least one soft needle bioelectrode 12 formed on the soft needle base 17, the soft needle bioelectrode 12 and the hard needle bioelectrode 11 are fixed via a first fixing member 6, and the soft needle base 17 and the hard needle base 16 are fixed via a second fixing member 5. The first fixing member 6 and the second fixing member 6 together constitute the above-mentioned fixing structural member, which functions to fix the hard needle 3 and the soft needle 4, ensure that the soft needle 4 can be implanted into tissue together with the hard needle 3, and ensure that no displacement occurs between the hard needle 10 and the soft needle 11. The integrated circuit chip 2 and the soft needle substrate 17 are bonded and fixed together to form an electrical connection, thereby realizing real-time, rapid and accurate extraction and stimulation of neural signals.

[0027] The specific structural design of the first fixing member 6 and the second fixing member 5 must satisfy the following requirements when implanting the microneedle into tissue: the soft needle 4 must be fixed, and the hard needle 3 must be able to move the soft needle 4 and be implanted into the tissue together with it; and when withdrawing the hard needle 3, the soft needle 4 and the hard needle 3 must be easily separated. Therefore, in a possible preferred embodiment, one specific structure of the first fixing member 6 and the second fixing member 5 is provided. 3, 4, and 5, the first fixing member 6 is a plurality of hook structures 13 spaced apart along the length of the hard needle bioelectrode 11, each of which has a first portion and a second portion. The second portion has both ends connected to the first portion and the surface of the hard needle bioelectrode 11, respectively. The first portion is parallel to the surface of the hard needle bioelectrode 11, the soft needle bioelectrode 12 is located between the first portion and the surface of the hard needle bioelectrode 11, and the second portion forms a predetermined angle with the surface of the hard needle bioelectrode 11. Accordingly, the soft needle bioelectrode 12 has an opening 14 at a position corresponding to the hook structure 13, through which the hook structure 13 passes. The opening 14 is provided with a hook detachment structure for detaching the hook structure 13 from the soft needle 4. Specifically, the first and second portions of the hook structure 13 and the surface of the hard needle bioelectrode 11 form a slot, the slot facing the tip of the hard needle 3, and the hook detachment structure located at the end remote from the tip of the soft needle 4. When fabricating a microneedle body combining the hard needle 3 and the soft needle 4, first, a sacrificial layer of a certain thickness is grown on the surface of the hard needle 3, then the soft needle 4 is grown on the surface of the sacrificial layer, an opening 14 is formed in the soft needle bioelectrode 12 of the soft needle 4, a hook detachment structure is patterned on the soft needle 4, then the second portion of the hook structure 13 is grown at the position of the opening 14, and finally the first portion of the hook structure 13 is grown, and then the sacrificial layer between the hard needle 3 and the soft needle 4 is removed.As a result, a portion of the soft needle bioelectrode 12 at the edge of the opening 14 is pushed into the hook structure 13, and when the hard needle 3 is implanted into the tissue, the hook structure 13 is used to move and implant the soft needle 4 together. When the implantation point is reached, the hard needle 3 is pulled backward, and when the hook structure on the hard needle bioelectrode 11 comes into contact with the hook detachment structure at the rear end of the opening 14, the hook detachment structure detaches the hook detachment structure 13 from the soft needle bioelectrode 12, releasing the fixation between the soft needle bioelectrode 12 and the hard needle bioelectrode 11. This achieves the purpose of withdrawing the hard needle 3 and leaving the soft needle 4 in the tissue.

[0028] 5, the hook release structure is preferably two hook release portions 15 extending from the edge of the opening 14 toward the inside of the opening 14, the two hook release portions 15 being arranged symmetrically about the axis of the opening 14, there being a gap between the two hook release portions 15, the gap being smaller than the width of the second portion of the hook structure 13, and there being a gap between the side edges of the two hook release portions 18 and the corresponding side edges of the opening 14 so that the hook release portions 15 can bend upward and be pressed from both sides. When the hard needle 3 is pulled backward and the hook structure 13 comes into contact with the hook release portions 15, the hook release portions 15 are slowly bent upward, causing the hook structure 13 to retract downward from the opening 14. Preferably, the two hook detachment portions 15 and the soft needle bioelectrode 12 are formed as an integral structure, so that as the two hook detachment portions 15 open upward, the second portion of the hook structure 13 presses the hook detachment portion 15, bending it upward in the direction of retraction of the hard needle 3. This widens the area of ​​the opening 14, and the hook structure 13 detaches from the soft needle 4 through the opening 14. Because the soft needle 4 and the hook detachment portion 15 are made of an elastic material, when the hard needle 3 detaches from the soft needle 4, the bent portion of the hook detachment portion 15 lowers and returns to its original shape.

[0029] 3 to 5, the first and second parts of the hook structure 13 are preferably integrally molded to increase the strength of the hook structure 13. In the process of separating the hard needle 3 and the soft needle 4, to facilitate the release of the hook structure 13 from the opening 14 and to prevent the first part from affecting the hook release part 15 when the hook structure 13 presses against it, the bottom surface of the second part in this embodiment abuts against the surface of the hard needle bioelectrode 11, the top surface of the second part abuts against the bottom surface of the first part, and the bottom surface of the second part is larger than the top surface of the second part. Preferably, in this embodiment, the angle between the second portion of the hook structure 13 and the surface of the hard needle bioelectrode 11 is set to an acute angle so as to facilitate detachment of the hard needle 3 from the soft needle 4. This prevents the first portion from exceeding the end of the second portion in the direction away from the needle tip of the hard needle 3, and also makes it easier for the second portion of the hook structure 13 to press the hook detachment portion 15 and bend it upward.

[0030] Regarding one specific structure of the second fixing member 5, as shown in Figures 6, 7 and 8, the second fixing member 5 is a plurality of pin structures 18 arranged on the hard needle base 16 at intervals in the width direction of the hard needle 3, and the pin structure 18 is composed of a large-diameter upper cylinder and a small-diameter lower cylinder that are coaxially arranged, and the soft needle base 17 has pin holes 20 formed at positions corresponding to the pin structures 18, and the soft needle base 17 has a plurality of centrally symmetric patterns 19 on the outside along the edges of the pin holes 20, for example, the centrally symmetric pattern 19 in the pattern in this embodiment may be a petal-shaped structure, and the diameter of the upper cylinder of the pin structure 18 is larger than the diameter of the pin hole 20. When fixing the hard needle 3 and the soft needle 4, the upper cylinder on the pin structure 18 is inserted into the corresponding pin hole 20 of the soft needle base 17. Because the diameter of the upper cylinder of the pin structure 18 is larger than the diameter of the pin hole 20, the upper cylinder presses against a part of the soft needle structure at the edge of the pin hole 20, fixing the soft needle 4 and ensuring that no displacement occurs between the hard needle 3 and the soft needle 4. After the hard needle 3 moves the soft needle 4 and is implanted into the tissue, the pin structure 18 is pulled downward until it is completely retracted, causing the upper cylinder of the pin structure 18 to apply a certain downward force to the soft needle 4 and bending the central symmetric pattern 19 of the soft needle 4 to a certain extent. Next, the hard needle 3 is pulled backward to retract the hook structure 13 on the hard needle 3, completely separating the hard needle 3 from the soft needle 4. The hard needle 3 is then pulled out, leaving the soft needle 4 in the tissue.

[0031] In this embodiment, the center point of the centrally symmetric pattern 19 and the center point of the pin hole 20 coincide with each other.

[0032] Preferably, the connection position between the soft needle base 17 and the integrated circuit chip 2 is located between the second fixing member 5 and the soft needle bioelectrode 12. This structural design effectively reduces the impact of the downward pulling force on the connection between the soft needle base 17 and the integrated circuit chip 2 during the process of pulling the hard needle 3 downward to separate the soft needle base 17 from the hard needle base 16, thereby ensuring the stability of the connection between the integrated circuit chip 2 and the soft needle 4.

[0033] 1, 9 and 10, the integrated circuit chip 2 includes a soft needle connecting portion 7 used to connect with the soft needle 4, and a microstrip line connecting portion 10 located on one side of the soft needle connecting portion 7 and used to connect with the microstrip line 1. Preferably, the integrated circuit chip 2 and the soft needle 4 of the microneedle body are electrically connected by a flip-chip method, and the microstrip line 1 and the integrated circuit chip 2 are electrically connected by a flip-chip method, and the microneedle body and the microstrip line 1 are directly flip-chip bonded to the integrated circuit chip 2, thereby realizing real-time, rapid and accurate extraction and stimulation of neural signals and maximally reducing transmission loss and noise signals, thereby ensuring stable and loss-free signal transmission.

[0034] Furthermore, when there are multiple composite microneedle structures as described above, the integrated circuit chip 2 may be configured to include chip connection portions 8 used to connect to other integrated circuit chips 2, and the chip connection portions 8 are located at both ends of the soft needle connection portion 7, and connection through holes 9 are formed in the chip connection portions 8, and one microneedle body and the integrated circuit chip 2 are connected according to the connection method in the above-mentioned embodiment, and the connection and fixation of multiple integrated circuit chips 2 to each other is achieved by using steel pins to connect and fix the connection through holes 9 of each integrated circuit chip 2, thereby assembling the microneedle body into a planar array structure and expanding the application range of the composite microneedle structure.

[0035] In conclusion, the integrated circuit chip-based composite microneedle structure provided by the present application can effectively fix the soft needle and the hard needle, preventing their relative movement, by using a hard needle to introduce the soft needle into tissue and then withdrawing the hard needle. This avoids the drawbacks of using only a hard needle or a soft needle. Furthermore, the integration of the microneedle body with the integrated circuit chip can realize the on-site collection and stimulation of neural signals, thereby optimizing the functionality of the neural interface and better meeting clinical needs.

[0036] The above examples are merely illustrative of the present application and do not constitute limitations on the scope of protection of the present application, and all designs identical or similar to those of the present application fall within the scope of protection of the present application. [Explanation of symbols]

[0037] 1 Microstrip line 2. Integrated circuit chips 3 Hard Needle 4 Soft Needle 5 Second fixing member 6 First fixing member 7 Soft needle connection 8 Chip connection 9 Connection through-hole 10 Microstrip line connection 11 Hard Needle Bioelectrodes 12 Soft Needle Bioelectrodes 13 Hook structure 14 Aperture 15 Hook release part 16 Hard needle base 17 Soft needle base 18-pin structure 19 Centrally symmetric patterns 20 pin holes

Claims

1. a microstrip line, at least one microneedle body, and at least one integrated circuit chip; the microneedle body includes a hard needle and a soft needle, the soft needle is fixed to the upper surface of the hard needle via a fixing structural member, the integrated circuit chip is provided on a base of the microneedle body, the integrated circuit chip is fixed to the soft needle of the microneedle body to form an electrical connection, and the microstrip line is fixed to one end of the integrated circuit chip to form an electrical connection; the hard needle has a hard needle base and at least one hard needle bioelectrode formed on the hard needle base, the soft needle has a soft needle base and at least one soft needle bioelectrode formed on the soft needle base, the soft needle base is fixed to the hard needle base, and the soft needle bioelectrode is fixed to the hard needle bioelectrode; the fixing structural member includes a first fixing member used to fix the soft-needle bioelectrode and the hard-needle bioelectrode, and a second fixing member used to fix the soft-needle base and the hard-needle base; the first fixing member is a plurality of hook structures spaced apart in the longitudinal direction of the hard needle bioelectrode, the hook structures having a first portion and a second portion, both ends of the second portion being connected to the first portion and the surface of the hard needle bioelectrode, respectively, the first portion and the surface of the hard needle bioelectrode being parallel, the soft needle bioelectrode being located between the first portion and the surface of the hard needle bioelectrode, and the second portion and the surface of the hard needle bioelectrode forming a predetermined angle; The second fixing member is a plurality of pin structures arranged on the hard needle base at intervals in the width direction of the hard needle, the pin structures being composed of a large-diameter upper cylinder and a small-diameter lower cylinder that are coaxially arranged, pin holes are formed in the soft needle base at positions corresponding to the pin structures, and the soft needle base is provided with a plurality of centrally symmetrical patterns that are openings on the outside along the edges of the pin holes, and the diameter of the upper cylinder of the pin structure is larger than the diameter of the pin holes. A composite microneedle structure based on an integrated circuit chip, characterized in that:

2. The predetermined angle between the second portion of the hook structure and the hard-needle bioelectrode is an acute angle.

2. A composite microneedle structure based on the integrated circuit chip of claim 1.

3. The soft needle bioelectrode has an opening at a position corresponding to the hook structure through which the hook structure passes, and the opening has a hook detachment structure for detaching the hook structure from the soft needle. The first and second parts of the hook structure and the surface of the hard needle bioelectrode form a slot, and the slot faces the tip of the hard needle. The hook detachment structure is provided at an end of the soft needle far from the tip.

2. A composite microneedle structure based on the integrated circuit chip of claim 1.

4. The hook release structure is a hook release portion extending from an edge of the opening toward the inside of the opening, the spacing between the hook release portions is smaller than the width of the second portion of the hook structure, the hook release portions are arranged symmetrically with respect to the axis of the opening, and there is a gap between the side edge of the hook release portion and the corresponding side edge of the opening. The composite microneedle structure based on the integrated circuit chip of claim 3.

5. The connection position between the soft needle base and the integrated circuit chip is located between the second fixing member and the soft needle bioelectrode.

2. A composite microneedle structure based on the integrated circuit chip of claim 1.

6. The integrated circuit chip includes a soft needle connection portion used to connect to the soft needle, and a microstrip line connection portion located on one side of the soft needle connection portion and used to connect to the microstrip line, the integrated circuit chip and the soft needle of the microneedle body are electrically connected by a flip chip method, and the microstrip line and the integrated circuit chip are electrically connected by a flip chip method.

2. A composite microneedle structure based on the integrated circuit chip of claim 1.

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