Triglyceride detergent

Abstract

To provide a detergent having excellent detergency against triglyceride.SOLUTION: A detergent against triglyceride which is for scalp and / or hair use containing at least one kind selected from the group consisting of polyoxyethylene fatty acid glyceryl and / or alkyl glucoside. Further, a detergent for scalp and / or hair use containing at least one kind selected from the group consisting of polyoxyethylene (capryl / capric acid) glyceryl, and (b) taurine, Coptis japonica extract, Phellodendron amurense extract, and Rubus suavissimus extract.SELECTED DRAWING: None

Description

Technical Field

[0001] The present invention relates to a detergent having excellent detergency against triglycerides.

Background Art

[0002] Human scalp sebum is composed of triglycerides, free fatty acids, squalene, wax esters, etc. Among them, it is reported that triglycerides account for about 40% as the main component (Non-Patent Document 1). Sebum covers the skin surface and plays physiological roles such as preventing the invasion of foreign substances from the outside and preventing the leakage of moisture from the body. On the other hand, excessive sebum secretion may cause various scalp troubles (such as bad odor, dandruff, stickiness, inflammation, etc.). In recent years, due to the increasing trend of cleanliness, daily care with hair cleaning agents (such as shampoos) having excellent sebum detergency has been demanded.

[0003] The essential component for a hair cleaning agent to exhibit a cleaning effect on sebum stains is a surfactant. Examples of the cleaning mechanism of surfactants include rolling up, emulsification, solubilization, etc. In the cleaning mechanism of hair cleaning agents such as shampoos, solubilization is related, and the involvement of other mechanisms is unclear (Non-Patent Document 2). Therefore, in order to effectively remove sebum stains, it is necessary to add a sufficient amount of surfactant that can solubilize sebum components. On the other hand, the use of excessive surfactants may also cause the outflow of intercellular lipids that originally play a barrier function of the skin, and there is also a risk of damaging the healthy skin state. From the above viewpoints, in order to sufficiently remove sebum stains even in a small amount, a detergent having excellent detergency against sebum stains (especially triglycerides, which is its main component) is required to be selected, but such studies have been insufficient so far.

Prior Art Documents

Non-Patent Documents

[0004]

Non-Patent Document 1

[0005] The object of this invention is to provide a cleaning agent that has excellent cleaning power against triglycerides, which are the main components of sebum stains. [Means for solving the problem]

[0006] The inventors screened triglyceride detergents by measuring the solubilization limit concentrations of various components against triolein, a type of triglyceride. As a result, they found that polyoxyethylene fatty acid glyceryl and alkyl glucoside have remarkably superior cleaning power against triglycerides. Furthermore, they discovered that combining polyoxyethylene (caprylic / capric acid) glyceryl with specific components or extracts dramatically improves its cleaning power, thus completing the present invention.

[0007] In other words, the present invention is (1) A cleansing agent for triglycerides, characterized by containing polyoxyethylene fatty acid glyceryl and / or alkyl glucoside, and being for use on the scalp and / or hair. (2) The detergent according to (1), wherein the triglyceride is triolein. (3) The detergent according to (1) or (2), wherein the polyoxyethylene fatty acid glyceride is polyoxyethylene coconut oil fatty acid glyceryl or polyoxyethylene (caprylic / capric acid) glyceryl. (4) A detergent according to any of (1) to (3), wherein the alkyl glucoside is an alkyl (8-16) glucoside. (5) A cleansing agent characterized by containing (a) polyoxyethylene (caprylic / capric acid) glyceryl and (b) at least one selected from the group consisting of taurine, Coptis japonica extract, Phellodendron amurense extract, and Tencha extract, and being for use on the scalp and / or hair. That is the case. [Effects of the Invention]

[0008] The present invention makes it possible to provide a detergent that has excellent cleaning power against triglycerides. [Modes for carrying out the invention]

[0009] The triglyceride cleansing agent of the present invention contains polyoxyethylene fatty acid glyceryl and / or alkyl glucoside and is used for the scalp and / or hair. Furthermore, the cleansing agent of the present invention contains polyoxyethylene (caprylic / capric acid) glyceryl and at least one selected from the group consisting of taurine, Coptis japonica extract, Phellodendron amurense extract, and Tencha extract, and is used for the scalp and / or hair. Each of the above components can be appropriately used if they are of a quality commonly used in pharmaceuticals, quasi-drugs, or cosmetics.

[0010] Polyoxyethylene fatty acid glyceryls are highly safe nonionic surfactants with excellent emulsifying and dispersing properties, making them suitable for a wide range of uses in the cosmetics field. Specific examples of polyoxyethylene fatty acid glyceryls used include polyoxyethylene coconut oil fatty acid glyceryl, polyoxyethylene (caprylic / capric acid) glyceryl, polyoxyethylene caprylic acid glyceryl, polyoxyethylene glyceryl laurate, polyoxyethylene oleate glyceryl, and polyoxyethylene monococonut oil fatty acid glyceryl. Polyoxyethylene coconut oil fatty acid glyceryl and polyoxyethylene (caprylic / capric acid) glyceryl are more preferable. These can be used individually or in combination of two or more as appropriate.

[0011] The content of polyoxyethylene fatty acid glyceryl is not particularly limited as long as the desired effect is sufficiently imparted, but in the detergent of the present invention, it is preferably 0.01 to 20% by mass, more preferably 0.1 to 10% by mass.

[0012] Alkyl glucosides are nonionic surfactants derived from natural raw materials, in which sugars and higher alcohols are linked by glycosidic bonds. They are known as cleaning agents with excellent foaming properties and safety. Specific examples of alkyl glucosides used include alkyl(8-16) glucosides, with those having an alkyl group with 8-10 carbon atoms being more preferable. These may be used individually or in combination of two or more as appropriate.

[0013] The alkyl glucoside content is not particularly limited as long as the desired effect is sufficiently imparted, but in the detergent of the present invention, it is preferably 0.01 to 20% by mass, more preferably 0.1 to 10% by mass.

[0014] Taurine (also known as aminoethylsulfonic acid or 2-aminoethanesulfonic acid) is a compound defined by Cas No. 107-35-7 and can be produced by general chemical synthesis methods or by extraction from seafood, especially mollusks (octopus and squid). It can also be purchased from various reagent and raw material manufacturers.

[0015] The taurine content is not particularly limited as long as the desired effect is sufficiently imparted, but in the detergent of the present invention, it is preferably 0.001 to 10% by mass, more preferably 0.01 to 5% by mass.

[0016] Ouren extract is an extract obtained from the rhizome of Ouren (scientific name: Coptis japonica Makino) or other plants of the same genus. Oubaku extract is an extract obtained from the bark of Phellodendron amurense Ruprecht or other plants of the same genus, with the periderm removed. Tencha extract is an extract obtained from the leaves of sweet tea (scientific name: Rubus suavissimus), a plant belonging to the Rosaceae family. The extraction method for the above extracts is not particularly limited and can be carried out according to conventional methods. Any polar or non-polar solvent can be used as the extraction solvent, for example, water, ethanol, propylene glycol, 1,3-butylene glycol, and mixtures thereof can be used. The above extracts may be used as is, or, if necessary, they may be used after being concentrated, diluted, filtered, decolorized with activated carbon, deodorized, or precipitated with ethanol. Furthermore, the extracted solution may be concentrated to dryness, spray-dried, freeze-dried, or otherwise treated to obtain a dried product. Commercially available products can also be used.

[0017] The content of Coptis japonica extract, Phellodendron amurense extract, or Tencha extract is not particularly limited as long as the desired effect is sufficiently imparted, but in the detergent of the present invention, it is preferably 0.0001 to 5% by mass, more preferably 0.001 to 3% by mass.

[0018] In addition to the components described above, the cleansing agent of the present invention may contain various components commonly used in cosmetics, quasi-drugs, pharmaceuticals, etc., as long as they do not impair the effects of the present invention. For example, anionic surfactants (amino acid-based surfactants such as N-acylmethylalanine salt, N-acyl glutamate, N-acyl aspartate, N-acyl taurine salt, α-olefin sulfonate, fatty acid salt, sulfosuccinate, alkyl ether carboxylate, acyl lactate, alkyl sulfate, alkyl ether sulfate, polyoxyethylene alkyl ether sulfate, polyoxyethylene alkyl ether acetate, higher fatty acid alkanolamide sulfate, etc.), amphoteric surfactants (alkyl betaine type, alkylamide betaine type, amide sulfobetaine type, amino acid type, imidazoline type, amine oxide type, etc.), nonionic surfactants (polyoxyethylene alkyl ether, polyoxypropylene alkyl ether, polyethylene glycol fatty acid ester, polyethylene glycol fatty acid diester, glycerin ester, polyoxyethylene polyoxypropylene alkyl ether, fatty acid alkanolamide, glycerin fatty acid ester, polyglycerin fatty acid ester, sucrose fatty acid ester, propylene (Lenglycol fatty acid esters, sorbitan fatty acid esters, polyoxyethylene sorbitan mono fatty acid esters, polyoxyethylene sorbitan fatty acid esters, polyoxyethylene sorbitan fatty acid esters, polyoxyethylene hydrogenated castor oil, etc.), cationic polymers (cationized cellulose, cationized guar gum, cationized xanthan gum, polydimethylmethylene piperidinium chloride, dimethyldiallylammonium chloride / acrylamide copolymer, acrylamide / acrylic acid / dimethyldiallylammonium chloride copolymer, etc.), excipients, fragrances, cooling agents (menthol, peppermint oil, camphor, etc.), anti-inflammatory agents (guaiazulene, salicylic acid, glycyrrhizinate, glycyrrhetinic acid, etc.), disinfectants (chlorhexidine gluconate, isopropylmethylphenol, quaternary ammonium salts, piroctone olamine, etc.), preservatives (parabens (methylparaben, ethylparaben, butylparaben, propylparaben, etc.), benzoic acid or its salts, sodium dehydroacetate, phenoxyethanol, hinokitiol, etc.)Humectants (hyaluronic acid or its salts, chondroitin sulfate, etc.), extracts of various animals and plants, vitamins (retinol acetate, ascorbic acid, thiamine nitrate, cyanocobalamin, biotin, riboflavin, etc.), antioxidants (dibutylhydroxytoluene, sodium pyrosulfite, tocopherol, sodium edetate, ascorbic acid, isopropyl gallate, etc.), solubilizing aids (various vegetable oils, various animal oils, alkyl glyceryl ether, hydrocarbons, etc.), metabolic activators, gelling agents (water-soluble polymers, etc.), adhesives, etc. can be appropriately blended according to the purpose.

[0019] The detergent of the present invention can be used for applications such as cosmetics, quasi-drugs, and pharmaceuticals. Further, the detergent of the present invention is preferably used as a shampoo or a scalp cleaner.

Examples

[0020] Examples, comparative examples, and test examples are described below to more specifically explain the present invention, but the present invention is not limited by these examples and the like. Unless otherwise specified, the concentration represents "mass %".

[0021] (Test Example 1) The detergency was evaluated by measuring the solubilization limit concentration of various components with respect to triolein, which is a kind of triglyceride.

[0022] Purified water, triolein, and various components listed in Table 1 were weighed so that the final concentration was 1% and the final triolein concentration was 0.1 to 0.001%, and 10 g of mixed aqueous solutions with various concentrations were prepared. They were shaken at room temperature for 1 hour and then left standing at room temperature overnight. They were inverted and mixed and left standing (degassed) for 1 hour or more, and the absorbance at 600 nm of each surfactant / triolein mixed aqueous solution was measured as turbidity using an ultraviolet-visible spectrophotometer (UV-2450, Shimadzu Corporation). The values of turbidity with respect to the triolein concentration were plotted, and the triolein concentration at the point (refraction point) where the turbidity began to increase rapidly was calculated as the triolein solubilization limit concentration.

[0023] (Test Results) Triolein with a solubilization limit concentration of 0.001% or higher was considered to have excellent cleaning power (○), while those with a concentration of 0.001% or lower were considered to have insufficient cleaning power (×). The evaluation results are shown in Table 1.

[0024] [Table 1]

[0025] Examples 1-3, consisting of polyoxyethylene fatty acid glyceryl or alkyl glucoside, were found to have a high triolein solubilization limit concentration and excellent cleaning power against triolein. On the other hand, Comparative Examples 1-16, using other components, were found to have a low triolein solubilization limit concentration and insufficient cleaning power against triolein.

[0026] (Test Example 2) The effectiveness of improving cleaning power was evaluated by measuring the solubilization limit concentration when various components were combined.

[0027] Purified water, triolein, polyoxyethylene (caprylic / capric acid) glyceryl, and various components listed in Table 2 were weighed to the final concentrations listed in Table 2, so that the final triolein concentration was 0.07-0.001%, and 10 g of mixed aqueous solutions of various concentrations were prepared. The solutions were shaken at room temperature for 1 hour, and then left to stand overnight at room temperature. After mixing by inversion and standing for another 1 hour or more (degassing), the absorbance of the polyoxyethylene (caprylic / capric acid) glyceryl / triolein mixed aqueous solution at 600 nm was measured as turbidity using a UV-Vis spectrophotometer (UV-2450, Shimadzu Corporation). The turbidity values ​​against the triolein concentration were plotted, and the triolein concentration at the point where the turbidity began to increase rapidly (refraction point) was calculated as the triolein solubilization limit concentration.

[0028] (Test results) Compared to Example 2, combinations with an improvement rate of 10% or more in the triolein solubilization limit concentration were classified as having a superior cleaning power improvement effect (○), combinations with an improvement rate of 0 to less than 10% were classified as having an insufficient cleaning power improvement effect (△), and combinations with a negative improvement rate were classified as having no cleaning power improvement effect (×). The evaluation results are shown in Table 2.

[0029] [Table 2]

[0030] Examples 4-7 showed a dramatic improvement in the triolein solubilization limit concentration compared to Example 2, demonstrating that they are combinations with superior cleansing power. On the other hand, Comparative Examples 17-20, which combined other components, did not show an improvement in the triolein solubilization limit concentration, demonstrating that they are combinations with insufficient cleansing power improvement. Therefore, it was found that a combination of polyoxyethylene (caprylic / capric acid) glyceryl and components selected from taurine, Coptis japonica extract, Phellodendron amurense extract, and Tencha extract is superior as a cleansing agent for the scalp or hair. [Industrial applicability]

[0031] This invention makes it possible to provide a cleansing agent that has excellent cleansing power against triglycerides, which are the main components of sebum buildup on the scalp.

Claims

1. A cleansing agent for triglycerides, characterized by containing (a) polyoxyethylene (caprylic / capric acid) glyceryl and (b) at least one selected from the group consisting of taurine, Coptis japonica extract, Phellodendron amurense extract, and Tencha extract, and being for use on the scalp and / or hair.

2. The detergent according to claim 1, wherein the triglyceride is triolein.