Composition for milk replacer, milk replacer, and method for suppressing calf weaning loss.

A milk replacer composition with specific fatty acid triglycerides and a controlled feeding schedule addresses weaning loss in calves, enhancing growth and digestive development.

JP7849588B2Active Publication Date: 2026-04-22ZENKOKU RAKUNOGYO KYODO KUMIAI RENGOKAI +6
View PDF 4 Cites 0 Cited by

Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Patents
Current Assignee / Owner
ZENKOKU RAKUNOGYO KYODO KUMIAI RENGOKAI
Filing Date
2020-12-10
Publication Date
2026-04-22

AI Technical Summary

Technical Problem

Existing milk replacers cause weaning loss in calves around 50 days of age when transitioning from milk to starter and hay, leading to slowed growth.

Method used

A milk replacer composition containing specific saturated fatty acid triglycerides with 8, 10, and 4 carbon atoms, with a crude fat content of 12-28% by mass, is fed to calves, with a gradual increase and decrease feeding schedule, promoting growth hormone and glucagon-like peptide-2 secretion to support digestive tract development.

Benefits of technology

The solution effectively suppresses weaning loss, promoting calf growth by increasing body weight and height, enhancing starter and hay intake, and reducing digestive burden.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure 0007849588000011
    Figure 0007849588000011
  • Figure 0007849588000012
    Figure 0007849588000012
  • Figure 0007849588000001
    Figure 0007849588000001
Patent Text Reader

Abstract

To provide a composition for substitute milk and substitute milk that suppress weaning loss.SOLUTION: A composition for substitute milk 11 contains at least one compound selected from a first group, at least one compound selected from a second group, and at least one compound selected from a third group. The first group consists of saturated fatty acid having a carbon number 8, salt of saturated fatty acid having a carbon number 8, and glyceride of saturated fatty acid having a carbon number 8. The second group consists of saturated fatty acid having a carbon number 10, salt of saturated fatty acid having a carbon number 10, and glyceride of saturated fatty acid having a carbon number 10. The third group consists of saturated fatty acid having a carbon number 4, salt of saturated fatty acid having a carbon number 4, and glyceride of saturated fatty acid having a carbon number 4.SELECTED DRAWING: Figure 2
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The present invention relates to a composition for substitute milk, substitute milk, and calves Suppression of weaning loss and a method.

Background Art

[0002] Substitute milk is widely used to reduce the burden on cows during lactation and to promote the growth of calves during the nursing period (including the lactation period). Substitute milk is given to calves from an early stage after birth, for example, at the stage of 8 days old.

[0003] Substitute milk is given to calves in combination with solid feed called starter and hay. As the calf approaches weaning, substitute milk is gradually replaced by starter and hay towards weaning. In this way, the proportion of starter and hay in the total feed given to the calf is increased, and eventually, the supply of substitute milk is terminated and weaning occurs.

[0004] Most substitute milks are prepared by dissolving a solid composition for substitute milk, such as powder, in water (including so-called hot water). As a composition for substitute milk, for example, a composition containing 0.5% by weight or more of a medium-chain fatty acid having 6 to 10 carbon atoms or a salt thereof is described in Patent Document 1, and as main components, skim milk powder and / or soybean meal, and (a) a triglyceride of a medium-chain fatty acid having 6 to 12 carbon atoms, and (b) at least one selected from the group consisting of a medium-chain fatty acid having 6 to 12 carbon atoms, a monoglyceride of a medium-chain fatty acid having 6 to 12 carbon atoms, and a diglyceride of a medium-chain fatty acid having 6 to 12 carbon atoms are described in Patent Document 2.

[0005] Patent Document 3 describes a composition for feed given to calves until weaning, which contains at least triglycerides consisting of medium-chain fatty acids with 8 to 10 carbon atoms, peptides consisting of 3 to 10 amino acids, and carbohydrates. Patent Document 4 describes a composition containing (A) triesters composed of medium-chain fatty acids and glycerin: 70 to 98 parts by mass, (B) emulsifiers consisting of a combination of three types: polyoxyethylene sorbitan fatty acid ester, glycerin fatty acid ester (excluding triglycerin fatty acid ester), and sorbitan fatty acid ester (excluding polyoxyethylene sorbitan fatty acid ester), with a total HLB value of 9.9 to 10.6: 1 to 29 parts by mass, (C) water: 1 to 10 parts by mass, and (D) nutritional additives: 0 to 10 parts by mass, with the total amount of each component (A) to (D) being 100 parts by mass, which is dispersed in drinking water for livestock or liquids that livestock can ingest. [Prior art documents] [Patent Documents]

[0006] [Patent Document 1] Japanese Patent Application Publication No. 01-261350 [Patent Document 2] Japanese Patent Application Publication No. 5-219895 [Patent Document 3] Japanese Patent Application Publication No. 5-049410 [Patent Document 4] WO2016 / 151722 [Overview of the project] [Problems that the invention aims to solve]

[0007] However, around 50 days of age, when calves are replaced with starter milk or hay, a phenomenon called weaning loss is observed, which is known as weaning loss.

[0008] Therefore, the present invention relates to a milk replacer composition, milk replacer, and calf that suppress weaning loss. Suppression of weaning loss The purpose is to provide a method. [Means for solving the problem]

[0009] The milk replacer composition of the present invention is a milk replacer composition to be fed to calves, and contains a saturated fatty acid triglyceride with 8 carbon atoms, a saturated fatty acid triglyceride with 10 carbon atoms, and a saturated fatty acid triglyceride with 4 carbon atoms, and contains crude fat in the range of 12% by mass or more and 28% by mass or less, and the total mass of the saturated fatty acid triglyceride with 8 carbon atoms, the saturated fatty acid triglyceride with 10 carbon atoms, and the saturated fatty acid triglyceride with 4 carbon atoms is at least when the mass of the milk replacer composition is 100. 1.7 The mass of the triglyceride of the saturated fatty acid with 12 carbon atoms is 5 or less when the mass of the milk substitute composition is 100, and the mass of the triglyceride of the saturated fatty acid with 4 carbon atoms is at least 25 when the sum of the mass of the triglyceride of the saturated fatty acid with 8 carbon atoms and the mass of the triglyceride of the saturated fatty acid with 10 carbon atoms is 100.

[0010] carbon It is preferable that the saturated fatty acid triglycerides of type 4 are present in an amount of at least 3 units by mass, when the mass of crude fat is set to 100 units.

[0012] carbon The mass of the saturated fatty acid triglycerides is preferably 15 or less, when the mass of crude fat is set to 100. 。

[0013] It contains a total of 1.0% to 3.0% by mass of saturated fatty acid triglycerides with 8 carbon atoms and saturated fatty acid triglycerides with 10 carbon atoms, and also contains saturated fatty acid triglycerides with 4 carbon atoms. 0.6% by mass Preferably, it contains within a range of 3.0% by mass or less.

[0014] The milk substitute of the present invention is, Note It contains the milk substitute composition listed and water. When the mass of the milk substitute composition is 1, the mass of water is preferably 5 to 8.

[0015] Calf of the present invention Suppression of weaning lossThe method involves feeding the above-mentioned milk replacer composition to calves. It is preferable to start feeding the milk replacer composition to calves at the latest by 8 days old. During the feeding period of the milk replacer composition to calves, in the first half, a gradual increase period is provided where the feeding amount is gradually increased according to the age, and in the second half, a gradual decrease period is provided where the feeding amount is gradually decreased according to the age, and it is preferable to feed the milk replacer composition.

Advantages of the Invention

[0016] According to the present invention, weaning loss is suppressed.

Brief Description of the Drawings

[0017] [Figure 1] It is an explanatory diagram of the milk replacer composition. [Figure 2] It is an explanatory diagram of the milk replacer.

Modes for Carrying Out the Invention

[0018] The milk replacer composition 11 shown in FIG. 1 is an example of an embodiment of the milk replacer composition of the present invention and is a feed for calves. The milk replacer composition 11 is a so-called powder formed in a particulate state. For example, as shown in FIG. 1, it is housed in a bag 12 which is an example of a packaging container, and is transported and stored. The packaging container is not limited to the bag 12, and any container that does not deteriorate or denature the milk replacer composition 11 may be used. Other examples of the packaging container include cans, bottles, etc.

[0019] As shown in Fig. 2, the milk replacer composition 11 in powder form is dissolved in water 16 (including heated water, so-called "hot water" also conceptually) to form the milk replacer 17 for feeding calves. The temperature of the water used to dissolve the milk replacer composition 11 is preferably within the range of 40°C or higher and 60°C or lower, and the temperature of the milk replacer 17 for feeding calves is preferably within the range of 38°C or higher and 42°C or lower. Note that the milk replacer composition 11 is not completely soluble (dissolvable) in water within the above temperature range. Therefore, the milk replacer 17 is not a transparent liquid but semi-transparent or opaque. Therefore, the dissolving step 18 of dissolving the milk replacer composition 11 is a step of dissolving a part of the milk replacer composition 11 and leaving the rest in a dispersed state.

[0020] When the mass M11 of the milk replacer composition 11 is set to 1, the mass M16 of the water 16 is preferably within the range of 5 or more and 8 or less. In this example, when the mass M11 is set to 1, the mass M16 is set to 5. By setting the mass M16 to 5 or more when the mass M11 is 1, compared with the case of less than 5, the intake amount of each component contained in the milk replacer composition 11 is more ensured, and the milk replacer composition 11 functions more efficiently. Also, by setting the mass M16 to 5 or more when the mass M11 is 1, compared with the case of less than 5, the osmotic pressure of the milk replacer 17 is kept low, and the risk of diarrhea and the like is further reduced. By setting the mass M16 to 8 or less when the mass M11 is 1, compared with the case of exceeding 8, calves are more likely to intake it willingly, and thus a larger intake amount is ensured. Also, by setting the mass M16 to 8 or less when the mass M11 is 1, compared with the case of exceeding 8, since the concentration of the milk replacer 17 is high, the milk replacer composition 11 is more efficiently ingested.

[0021] The milk replacer composition 11 may be used in combination with at least one of starter and hay. Starter is a solid feed widely used as a concentrated feed, as is well known, and is said to contribute significantly to the development of the rumen (first stomach) during the so-called nursing period (including the lactation period) up to about 3 months of age. The starter may be a known product or a commercially available product. The starter used in this example is New Makestar manufactured by the National Federation of Dairy Cooperatives. The hay is not particularly limited as long as it can be given to calves, and may be a known product. The hay may be a commercially available product, and in this example, Crane® Grass manufactured by the National Federation of Dairy Cooperatives, which is commercially available, is used.

[0022] The milk replacer composition 11 can be given to calves that have reached an age where they can be given existing, commercially available, milk replacers. The start of feeding the milk replacer composition 11 to calves (hereinafter referred to as "start of feeding") is not particularly limited, but it is preferably no later than 7 days of age. However, the timing of the start of feeding may be appropriately changed depending on the calf's developmental stage, for example, it may be started earlier than 7 days of age, at 3 days of age, or later than 7 days of age.

[0023] The end of feeding (hereinafter referred to as "end of feeding") is not particularly limited, but is preferably at least 42 days old, more preferably at least 49 days old, and even more preferably at least 56 days old. Thus, it is preferable to feed the milk replacer composition 11 to calves before they reach 56 days old. However, the timing of the end of feeding may be changed as appropriate depending on the calf's developmental stage, and feeding may be continued even for calves that have exceeded 56 days old. In this example, for example, it is set at 64 days old. During the feeding period from the start of the first feeding to the end of the last feeding, it is preferable to feed every day, but there may be non-feeding days on which the milk replacer composition 11 is not fed. On these non-feeding days, other milk replacer feeds may be fed.

[0024] The amount of milk replacer composition 11 to be given per day is not particularly limited, but it is preferable to provide a period of gradual increase in the amount given according to the age of the animal during the feeding period, and a period of gradual decrease in the amount given according to the age of the animal. In the following explanation, the amount given per day will be referred to as "feeding amount". As mentioned above, milk replacer composition 11 is a powder, so the unit of feeding amount will be g / d, which is the unit of dry matter. Since the starter and hay contain moisture, the unit of feeding amount will be gAF / d, which is the so-called actual amount (mass in the state in which it is given), including the case when moisture is present. "AF" is an abbreviation for as fed.

[0025] It is preferable to set the gradual increase period in the first half of the feeding period and the gradual decrease period in the second half of the feeding period. It is preferable to set a fixed period between the gradual increase period and the gradual decrease period during which the amount of feed is kept roughly constant, and this is done in this example as well. The gradual increase period is preferably the period from the start of feeding to 36 days of age, more preferably the period from the start of feeding to 29 days of age, even more preferably the period from the start of feeding to 22 days of age, and particularly preferably the period from the start of feeding to 15 days of age. The gradual decrease period is preferably the period from 36 days of age to the end of feeding, more preferably the period from 43 days of age to the end of feeding, and even more preferably the period from 50 days of age to the end of feeding. In this example, feeding is set to start at 8 days of age, the gradual increase period is set from 8 days of age to 22 days of age, the fixed period is set from 22 days of age to 50 days of age, and the gradual decrease period is set from 50 days of age to 63 days of age (the age on the day before 64 days of age when feeding ends (the amount of feed is zero)).

[0026] The initial amount of the milk replacer composition 11 to be given is preferably in the range of 400 g / d to 700 g / d, and in this example it is set at 600 g / d. During the gradual increase period, it is preferable to increase the amount by 50 g / d to 150 g / d each day, and in this example it is increased by 100 g / d each day. During the fixed period, the amount to be given is set at 1400 g / d in this example. However, the amount to be given during the fixed period is not limited to this example and may be set in the range of 500 g / d to 2000 g / d, more preferably in the range of 500 g / d to 1500 g / d, and may be changed depending on the prescription, for example, and in another embodiment it is set at 500 g / d. During the gradual decrease period, it is preferable to decrease the amount by 50 g / d to 150 g / d each day, and in this example it is decreased by 100 g / d each day. The amount to be given at the end of feeding of the milk replacer composition 11 in this example is 600 g / d.

[0027] During the feeding period of the milk replacer composition 11, it is preferable to feed a starter, and more preferable to feed both the starter and hay. The amount of starter should be gradually increased according to the calf's age and should be fed in accordance with the calf's intake, and there is no need to set an upper limit on the amount to be fed. In addition, the starter may be fed once a day when the amount to be fed is small, and when the amount to be fed becomes large, it may be fed in two doses, for example, in the morning and evening. In this example, the initial amount to be fed is 200g AF / d and given in one dose, and when the remaining amount reaches 100g, an additional 300g is added, and when the amount to be fed reaches 1100g AF / d or more, it is fed in two doses, in the morning and evening. In this way, the starter may be fed by adding new starter when the remaining amount reaches a predetermined amount.

[0028] Similarly, with hay, the amount given should be gradually increased according to the calf's age, and the amount should be adjusted according to the calf's intake; there is no need to set an upper limit on the amount given. For hay, it is also acceptable to add new hay when the remaining amount reaches a predetermined level. In this example, the initial amount given was 100g AF / d, given in one sitting, and another 100g was added when the remaining amount reached 50g.

[0029] The milk replacer composition 11 may be given in a single dose in the set amount, or it may be given in multiple doses. However, even if a set amount is given, the calf does not necessarily consume the entire amount, and the amount consumed is often less than the amount given. However, it is preferable to set the above-mentioned increasing period, fixed period, and decreasing period, and set the above-mentioned amount for each period, so that the calf consumes almost the entire amount given.

[0030] The milk substitute composition 11 contains at least one compound selected from Group 1, at least one compound selected from Group 2, and at least one compound selected from Group 3. Each of Groups 1, 2, and 3 consists of the following multiple compounds. Group 1; saturated fatty acids with 8 carbon atoms (sometimes abbreviated as C8:0), salts of saturated fatty acids with 8 carbon atoms, and glycerides of saturated fatty acids with 8 carbon atoms. Group 2; saturated fatty acids with 10 carbon atoms (sometimes abbreviated as C10:0), salts of saturated fatty acids with 10 carbon atoms, and glycerides of saturated fatty acids with 10 carbon atoms. Group 3; saturated fatty acids with 4 carbon atoms (sometimes abbreviated as C4:0), salts of saturated fatty acids with 4 carbon atoms, and glycerides of saturated fatty acids with 4 carbon atoms.

[0031] Glycerides of saturated fatty acids with 8 carbon atoms are esters of saturated fatty acids with 8 carbon atoms and glycerol, and may be monoglycerides, diglycerides, or triglycerides of saturated fatty acids with 8 carbon atoms, or a mixture of at least two of these. Similarly, glycerides of saturated fatty acids with 10 carbon atoms are esters of saturated fatty acids with 10 carbon atoms and glycerol, and may be monoglycerides, diglycerides, or triglycerides of saturated fatty acids with 10 carbon atoms, or a mixture of at least two of these. Similarly, glycerides of saturated fatty acids with 4 carbon atoms are esters of saturated fatty acids with 4 carbon atoms and glycerol, and may be monoglycerides, diglycerides, or triglycerides of saturated fatty acids with 4 carbon atoms, or a mixture of at least two of these. It is particularly preferable that the glycerides constituting at least one of the groups 1 to 3 are triglycerides.

[0032] In this example, each of the saturated fatty acids listed above is considered a straight-chain fatty acid. Specifically, the saturated fatty acid with 8 carbon atoms is octanoic acid (caprylic acid), the saturated fatty acid with 10 carbon atoms is decanoic acid (capric acid), and the saturated fatty acid with 4 carbon atoms is butanoic acid (butyric acid). However, even if a fatty acid has a branched structure, if it is a medium-chain or short-chain fatty acid with a short chain length, its function in terms of feeding to calves is expected to be no different from that of a straight-chain fatty acid, so a branched fatty acid is also acceptable. Furthermore, the saturated fatty acid with 12 carbon atoms described later is also a straight-chain fatty acid in this example, namely dodecanoic acid (lauric acid).

[0033] Salts of saturated fatty acids are not particularly limited and include, for example, sodium salts, calcium salts, and magnesium salts. In the following explanation, salts of saturated fatty acids with N carbon atoms (where N is a natural number) are referred to as N-carbon fatty acid salts, and triglycerides of saturated fatty acids with N carbon atoms are referred to as N-carbon fatty acid triglycerides.

[0034] Since the milk replacer composition 11 contains at least one compound selected from each of the first and second groups, the secretion of growth hormone, a growth factor, increases. This promotes the growth of calves, for example, by promoting an increase in body weight and height. Furthermore, since the milk replacer composition 11 contains at least one compound selected from the third group, the secretion of glucagon-like peptide-2 (GLP-2), which has a proliferative effect on the intestinal mucosa, is promoted, thereby promoting the development of the lower digestive tract, reducing the burden on the intestines when replacing starter and / or hay, and improving the digestive absorption of starter and hay. As a result, the intake of starter and / or hay by calves does not decrease, but may even increase. As a result, combined with the effect of promoting calf growth by the action of at least one compound selected from each of the first and second groups, an increase in body weight and height is further promoted. For example, the burden of a significant change in feed to starter and hay around 50 days of age is reduced, and so-called weaning loss, which slows growth, is suppressed. In this way, with the milk replacer composition 11, at least one compound selected from each of the first and second groups, and at least one compound selected from the third group work together to reliably promote the growth of the calf. The mass MA of the compounds selected from each of the first to third groups is preferably at least 1.5, more preferably at least 1.7, and even more preferably at least 3.0, when the total mass of the milk replacer composition 11 is 100. The mass PA is preferably at least 9, more preferably at least 16, and even more preferably at least 17, when the mass MF of the crude fat described later is 100.

[0035] From Group 1, a fatty acid triglyceride with 8 carbon atoms is selected; from Group 2, a fatty acid triglyceride with 10 carbon atoms is selected; and from Group 3, a fatty acid triglyceride with 4 carbon atoms is selected, which is more preferable. The milk replacer composition 11 in this example also contains a fatty acid triglyceride with 8 carbon atoms, a fatty acid triglyceride with 10 carbon atoms, and a fatty acid triglyceride with 4 carbon atoms. The milk replacer composition 11 in this example does not contain (is not contained in) the fatty acids and fatty acid salts of Groups 1, 2, and 3, but they may be contained together with the fatty acid triglycerides. The fatty acid triglycerides with 8 carbon atoms, fatty acid glycerides with 10 carbon atoms, and fatty acid glycerides with 4 carbon atoms are liquids and have less odor than fatty acids and fatty acid salts, which is preferable from the viewpoint of ease of handling and ease of manufacturing the milk replacer composition 11.

[0036] The milk substitute composition 11 preferably contains at least 25 units of carbon-4 fatty acid triglycerides when the sum of the masses of carbon-8 fatty acid triglycerides and carbon-10 fatty acid triglycerides is 100. That is, when the mass of carbon-8 fatty acid triglycerides is MC8, the mass of carbon-10 fatty acid triglycerides is MC10, and the mass of carbon-4 fatty acid triglycerides is MC4, it is preferable that MC4 is 25 or more relative to the mass sum of MC8 + MC10, which is 100. It is more preferable that MC4 is 25 to 70 relative to the mass sum of MC8 + MC10, which is 100.

[0037] Since the milk replacer composition 11 contains 4-carbon fatty acid triglycerides with a mass of MC4 of 25 or more relative to a mass sum of MC8 + MC10 of 100, the effect of increasing the secretion of growth hormone by 8-carbon fatty acid triglycerides and 10-carbon fatty acid triglycerides is more effectively utilized, thereby further promoting the growth of calves.

[0038] Carbon 12 fatty acid triglycerides have strong antibacterial properties. Therefore, it is preferable that the milk replacer composition 11 does not contain too much carbon 12 fatty acid triglycerides. This suppresses the antibacterial effect of carbon 12 fatty acid triglycerides, thereby further promoting the development of the lower digestive tract. When the mass of carbon 12 saturated fatty acid triglycerides is denoted as MC12, the mass MC12 is preferably 5 or less, and may be 0 (zero), when the mass of the milk replacer composition 11 is taken as 100%. That is, when the total mass of the milk replacer composition 11 is taken as 100%, the mass MC12 is preferably in the range of 0% to 5%. By keeping the mass MC12 of the milk replacer composition 11, when the total mass is taken as 100%, to 5% or less, the amount of fat accumulated in the liver is reliably suppressed, thereby preventing excessive burden on the liver. As a result, the calf growth-promoting effect of compounds selected from each of the first to third groups can be obtained while more reliably suppressing the burden on the liver. The mass MC12, when the total mass of the milk replacer composition 11 is taken as 100%, is more preferably in the range of 0% to 2.6%, and even more preferably in the range of 0% to 2.0%.

[0039] The mass MC12 of the 12-carbon fatty acid triglyceride is more preferably 15 or less when the mass of crude fat is set to 100. That is, in the milk substitute composition 11, when the mass of crude fat is set to MF, it is more preferable that the mass MC12 is kept low at 15 or less with respect to MF, which is set to 100. The mass MC12 with respect to MF, which is set to 100, may be 0 (zero). By keeping the mass MC12 with respect to MF, which is set to 100, the development of the lower digestive tract by the 4-carbon fatty acid triglyceride is more reliably promoted under the action of the 8-carbon fatty acid triglyceride and the 10-carbon fatty acid triglyceride. In addition, by keeping the mass MC12 with respect to MF, which is set to MF, to 15 or less, the excessive amount of fat in the liver is more reliably suppressed. When MF is set to 100, it is more preferable that the mass MC12 with respect to MF be kept at 12 or less, and even more preferable that it be kept at 10.9 or less.

[0040] The milk replacer composition 11 preferably contains crude fat, and this is the case in this example as well. In this case, it is preferable that the carbon-4 fatty acid triglyceride is contained in an amount of at least 3 by mass when the mass MF of the crude fat is set to 100. That is, it is preferable that the milk replacer composition 11 contains carbon-4 fatty acid triglyceride in an amount of 3 or more by mass MC4 when the mass MF is set to 100. This allows calves that are consuming a small amount of milk replacer composition 11, i.e., calves in their early stages of life, to ingest a sufficient amount of carbon-4 fatty acid triglyceride to achieve an effective result, and the lower digestive tract can develop more easily from a very early stage of nursing.

[0041] The milk replacer composition 11 preferably contains crude fat in the range of 10% by mass or more and 30% by mass or less, more preferably in the range of 12% by mass or more and 28% by mass or less, and even more preferably in the range of 15.0% by mass or more and 25.5% by mass or less. When the crude fat content is 10% by mass or more, energy is absorbed more efficiently compared to when it is less than 10%. Also, when the crude fat content is 30% by mass or less, the intake of starter and hay is less likely to be suppressed compared to when it exceeds 30% by mass, and calves consume more starter and hay.

[0042] The milk substitute composition 11 preferably further contains crude protein. In this example, crude protein is contained in a mass proportion of 28.0%.

[0043] The milk substitute composition 11 may further contain other materials. For example, vitamins, minerals (trace minerals), microorganisms such as butyrate-producing bacteria, lactic acid bacteria, and bifidobacteria, and immune antibodies. It is not necessary to include fatty acid triglycerides with 5, 7, 9, and 11 carbon atoms. The milk substitute composition 11 in this example also does not contain fatty acid triglycerides with 5, 7, 9, and 11 carbon atoms.

[0044] The milk substitute composition 11 is manufactured by mixing the materials such as the compounds listed above. However, if there is a base composition (hereinafter referred to as the base composition) for the milk substitute composition 11, it may be manufactured by adding the materials such as the compounds listed above to the base composition, or by removing a predetermined amount of, for example, a 12-carbon fatty acid triglyceride from the base composition.

[0045] The milk substitute composition 11 can be manufactured, for example, by mixing oil and fat with a water-soluble liquid raw material, then mixing with an emulsifier, homogenizing the resulting mixture to obtain powdered oil and fat, and then mixing this powdered oil and fat with other powdered raw materials. Examples of powdered raw materials to be mixed with powdered oil and fat include milk components, proteins or their denatured products and hydrolysates thereof, and other powdered raw materials. Examples of milk components include powdered milk (skim milk powder, whole milk powder, etc.) and whey (whey protein concentrate (WPC), dried whey, etc.). Examples of proteins include soybean meal, concentrated soybean protein, wheat protein, casein, and gluten. Examples of other powdered raw materials include carbohydrates, vitamins, minerals, seasonings, and spices. For example, the technology described in Japanese Patent Application Publication No. 2012-210230 may also be used.

[0046] The milk substitute composition 11 preferably contains a combination of 8-carbon fatty acid triglycerides and 10-carbon fatty acid triglycerides in an amount of 1.0% by mass or more and 3.0% by mass or less. The milk substitute composition 11 preferably contains 4-carbon fatty acid triglycerides in an amount of 0.5% by mass or more and 3.0% by mass or less.

[0047] Table 1 shows five examples of the more detailed composition of milk replacer composition 11. Table 1 shows the mass percentages of crude fat, 4-carbon fatty acid triglycerides, 8-carbon fatty acid triglycerides, 10-carbon fatty acid triglycerides, and 12-carbon fatty acid triglycerides, with the total mass of each milk replacer composition 11A to 11E set to 100%. As shown in Table 1, the crude fat in all of the milk replacer compositions 11A to 11E contains 4-carbon fatty acid triglycerides, 8-carbon fatty acid triglycerides, 10-carbon fatty acid triglycerides, and 12-carbon fatty acid triglycerides. The sum of the masses of triglycerides of 4-carbon fatty acids, 8-carbon fatty acids, and 10-carbon fatty acids in milk replacer compositions 11A to 11D, respectively, is 3.4%, 3.8%, 4.1%, and 2.5%, respectively, when the total mass of milk replacer compositions 11A to 11D is set to 100%. Furthermore, the sum of the masses of triglycerides of 4-carbon fatty acids, 8-carbon fatty acids, and 10-carbon fatty acids in milk replacer compositions 11A to 11D, respectively, is 16%, 17%, 16%, and 17%, respectively, when the mass MF of crude fat is set to 100%.

[0048] [Table 1] [Examples]

[0049] [Example 1]~[Example 2] Two types of milk replacer compositions 11 were prepared, and the milk replacer 17 prepared with each of these compositions was fed to calves. The growth status during the nursing period and for 4 weeks after weaning was investigated, resulting in Examples 1 and 2. The calves at the start of feeding the milk replacer composition 11 were 8-day-old female Holstein calves. In each example, 10 calves were fed the milk replacer composition 11. The study period for investigating growth status was from 8 to 92 days of age, with weaning (end of feeding of milk replacer composition 11) at 64 days of age. The milk replacer 17 was prepared by mixing 1 part milk replacer composition 11 with 5 parts water (heated water) by mass. Starter and craingrass hay were fed throughout the study period. As described above, the starter and hay were fed ad libitum, with new food added when the remaining amount reached a predetermined level due to intake.

[0050] Table 2 shows the mass percentages of crude protein, crude fat, and the carbon 8, 10, 4, and 12 fatty acid triglycerides contained in the crude fat in each of the milk replacer compositions 11 of Examples 1 and 2. The values ​​shown in Table 2 are based on the total mass of milk replacer composition 11 being 100%. The mass percentages of carbon 4, 8, 10, and 12 fatty acid triglycerides in Table 2 are based on values ​​obtained by analyzing the composition of crude fat, and the composition of crude fat is shown in Table 3. The values ​​in Table 3 are based on the total mass of crude fat being 100%. According to Table 2, the sum of the masses of carbon 4 fatty acid triglycerides, carbon 8 fatty acid triglycerides, and carbon 10 fatty acid triglycerides in Examples 1 and 2 are 1.7% and 3.0%, respectively, when the total mass of milk replacer composition 11 is set to 100%. According to Table 2, the sum of the masses of triglycerides of 4-carbon fatty acids, 8-carbon fatty acids, and 10-carbon fatty acids in the milk substitute compositions of Examples 1 and 2 is 9% and 17%, respectively, when the mass MF of crude fat is set to 100%, respectively.

[0051] [Table 2]

[0052] [Table 3]

[0053] Body weight and height were measured at the start of the study and every 7 days thereafter. The intake of milk replacer composition 11 (g / d), and the intake of starter and hay (gAF / d) were measured daily and compiled every 7 days, and the average for each 7-day period was calculated. The measured values ​​for each example were compared with Comparative Example 1 described below using one-way ANOVA. The results are shown in Tables 4-7.

[0054] Table 4 shows the average weight (kg) of 10 calves measured every 7 days from the start of the study. In Tables 4 to 7, "*" indicates a statistically significant difference (P<0.05) compared to Comparative Example 1, and "**" indicates a trend compared to Comparative Example 1 (P<0.10). Note that each table from Table 4 onwards is expressed as the mean ± standard error of the 10 calves.

[0055] Table 5 shows the average weight gain (kg) of the 10 animals, calculated every 7 days from the start of the study (hereinafter referred to as weight gain).

[0056] Table 6 shows the average height (cm) of the 10 animals, measured every 7 days from the start of the study.

[0057] Table 7 shows the average weight and height at the start of the study, weight at weaning, weight gain from the start of the study to weaning, height at weaning, weight at the end of the study, weight gain from the start to the end of the study, and height at the time of the study for 10 animals.

[0058] Furthermore, the average intake (g / d) of the milk replacer composition 11, the average intake (g / d) of the starter, and the average intake (g / d) of hay at each 7-day age are shown in Tables 8 to 10.

[0059] Table 8 shows the average intake (g / d) of milk replacer composition 11 at each 7-day age. Table 9 shows the average intake (g / d) of starter at each 7-day age. Table 10 shows the average intake (g / d) of hay at each 7-day age.

[0060] [Comparative Example 1]~[Comparative Example 2] Two different milk replacer compositions were prepared, and the milk replacer prepared using each of these compositions was fed to calves. The conditions were the same as in the example, but these were designated as Comparative Examples 1 and 2.

[0061] Table 2 shows the mass percentages of crude protein, crude fat, and the carbon 8, 10, 4, and 12 fatty acid triglycerides contained in the crude fat for each of the milk replacer compositions in Comparative Examples 1 and 2. The values ​​shown in Table 2 are based on the total mass of milk replacer composition 11 being 100%. The mass percentages of carbon 4, 8, 10, and 12 fatty acid triglycerides in Table 2 are based on values ​​obtained by analyzing the composition of crude fat, and the composition of crude fat is shown in Table 3. According to Table 2, the sum of the masses of carbon 4 fatty acid triglycerides, carbon 8 fatty acid triglycerides, and carbon 10 fatty acid triglycerides in Comparative Examples 1 and 2 are 1.1% and 2.4% respectively, when the total mass of milk replacer composition 11 is set to 100%. According to Table 2, the sum of the masses of triglycerides of 4-carbon fatty acids, 8-carbon fatty acids, and 10-carbon fatty acids in the milk substitute compositions in Comparative Examples 1 and 2 is 6% and 13%, respectively, when the mass MF of crude fat is set to 100%.

[0062] Similar to the example, body weight and height were measured at the start of the study and every 7 days thereafter, and the values ​​for each item in Tables 4 to 7 were obtained. For Comparative Example 2, the measured values ​​were compared with Comparative Example 1 using one-way ANOVA, similar to the example. The results are shown in Tables 4 to 7.

[0063] Furthermore, similar to the examples, the average intake of the milk replacer composition 11 (g / d) at each 7-day age, the average intake of the starter (g / d) at each 7-day age, and the average intake of hay (g / d) at each 7-day age were determined. The results are shown in Tables 8 to 10.

[0064] [Table 4]

[0065] [Table 5]

[0066] [Table 6]

[0067] [Table 7]

[0068] Example 1 tended to have a higher body weight at weaning compared to Comparative Example 1 (P<0.10). Example 1 had significantly greater body weight at weaning and greater weight gain from the start of the study to weaning compared to Comparative Example 1 (P<0.05). Example 2 tended to have a higher body height at weaning compared to Comparative Example 1 (P<0.10). Example 2 tended to have a higher body height at the end of the study compared to Comparative Example 1 (P<0.10).

[0069] [Table 8]

[0070] [Table 9]

[0071] [Table 10]

[0072] In both Example 1 and Example 2, the average intake of the milk substitute composition 11, starter, and hay was almost the same as in Comparative Example 1. Nevertheless, the intake of 4-carbon fatty acid triglycerides tended to result in greater body weight at weaning. By increasing the amounts of 8-carbon and 10-carbon fatty acid triglycerides compared to Comparative Example 1 and administering them in combination with 4-carbon fatty acid triglycerides, body weight and weight gain at weaning were significantly increased, and body height at weaning and at the end of the study tended to be greater. [Explanation of Symbols]

[0073] 11 Milk substitute composition 12 bags 16 water 17 Milk substitute 18 Melting process

Claims

1. In a milk replacer composition to be fed to calves, Triglycerides of saturated fatty acids with 8 carbon atoms, Triglycerides of saturated fatty acids with 10 carbon atoms, Triglycerides of saturated fatty acids with 4 carbon atoms, It contains, The total mass of the carbon-8 saturated fatty acid triglyceride, the carbon-10 saturated fatty acid triglyceride, and the carbon-4 saturated fatty acid triglyceride is at least 1.7 when the mass of the milk substitute composition is 100. The mass of the triglyceride of a saturated fatty acid having 12 carbon atoms is 5 or less, when the mass of the milk substitute composition is 100. The mass of the triglyceride of the saturated fatty acid having 4 carbon atoms is at least 25, when the sum of the mass of the triglyceride of the saturated fatty acid having 8 carbon atoms and the mass of the triglyceride of the saturated fatty acid having 10 carbon atoms is 100. A milk substitute composition containing crude fat in an amount of 12% by mass or more and 28% by mass or less.

2. When the mass of the crude fat is set to 100, the triglycerides of saturated fatty acids with 4 carbon atoms are The milk substitute composition according to claim 1, which contains at least 3 by mass.

3. The milk substitute composition according to claim 1 or 2, wherein the mass of the triglyceride of a saturated fatty acid having 12 carbon atoms is 15 or less when the mass of the crude fat is 100.

4. The triglycerides of the saturated fatty acids having 8 carbon atoms and the triglycerides of the saturated fatty acids having 10 carbon atoms are combined in an amount of 1.0% by mass or more and 3.0% by mass or less. The milk substitute composition according to any one of claims 1 to 3, comprising a triglyceride of a saturated fatty acid having 4 carbon atoms in an amount of 0.6% by mass or more and 3.0% by mass or less.

5. A milk substitute composition according to any one of claims 1 to 4, Water and A milk substitute containing [this ingredient].

6. The milk substitute according to claim 5, wherein when the mass of the milk substitute composition is 1, the mass of the water is 5 or more and 8 or less.

7. For calves, A method for suppressing weaning loss of calves, comprising feeding them a milk replacer composition according to any one of claims 1 to 4.

8. The method for suppressing calf weaning loss according to claim 7, wherein the feeding of the milk replacer composition to the calf is started at the latest at 8 days of age.

9. A method for suppressing weaning loss of calves according to claim 7 or 8, wherein the period of feeding the milk replacer composition to the calves includes a period of gradual increase in the amount to be fed in accordance with the age in days during the first half of the period, and a period of gradual decrease in the amount to be fed in accordance with the age in days during the second half of the period of feeding the milk replacer composition to the calves.

Citation Information

Patent Citations

  • JP1989261350A

  • Feed composition for calf

    JP1993049410A

  • Feed composition for baby domestic animal and method for raising baby domestic animal

    JP1993219895A

  • Feed composition, emulsion feed composition, and method for supplying feed composition

    WO2016151722A1