Vibration devices, vibration systems, extraction-ionization systems, mass spectrometry systems, and vibration methods.

Abstract

The present invention provides a vibration device which stabilizes vibration of a probe over a long period of time. The vibration device (1) is for causing a cantilever-supported probe to vibrate, said vibration device comprising a probe (2), two securing members (3, 4) supporting the probe (2) sandwiched therebetween, and vibration-generating unit (5) for imparting vibrations to at least one of the two securing members (3, 4), wherein a recess (10) in which the probe (2) is placed is formed on at least one of the two securing members (3, 4) at the position corresponding to the probe (2) when the probe (2) is sandwiched by the two securing members (3, 4).

Claims

[Claim 1] A vibrating device for vibrating a cantilevered probe, A probe with an axial shape, The probe comprises a first end which is the end of the main body, a second end which is the opposite end of the main body to the first end, and the main body between the first end and the second end. In a first direction perpendicular to the axial direction, first and second fixing members clamp and support the portion of the main body near the first end, The device comprises a vibration generating unit that applies vibration to at least one of the first and second fixing members, With the probe sandwiched between the first and second fixing members, a recess is formed in the first fixing member along its entire axial direction. The probe is positioned across the entire recess, The recess is a vibration device that, in cooperation with the first fixing member, restricts the movement of the probe in the axial direction and in a second direction perpendicular to the first direction. [Claim 2] The vibration device according to claim 1, wherein both of the first and second fixing members have permanent magnets, or one has a permanent magnet and the other has a magnetic material. [Claim 3] The vibration device according to claim 1, wherein the recess is pre-formed in the first fixing member. [Claim 4] The recess has a rectangular cross-sectional shape, The vibration device according to claim 3, wherein the probe positioned in the recess is in contact with one wall of the recess. [Claim 5] The vibration device according to claim 1, wherein the second fixing member, which does not have the recess formed thereon, is provided with a friction portion on the surface facing the probe that contacts the probe and restricts the movement of the probe by frictional force. [Claim 6] A vibrating device for vibrating a cantilevered probe, A probe with an axial shape, In a first direction perpendicular to the axial direction, the probe is supported by being sandwiched between first and second fixing members, The device comprises a vibration generating unit that applies vibration to at least one of the first and second fixing members, With the probe sandwiched between the first and second fixing members, a recess is formed in the first fixing member along its entire axial direction. The probe is positioned across the entire recess, The recess cooperates with the first fixing member to restrict the movement of the probe in the axial direction and in a second direction perpendicular to the first direction. The probe is a vibrating device having a channel through which a liquid flows. [Claim 7] The vibration device according to claim 1, further comprising a pressing portion for pressing the first fixing member against the probe. [Claim 8] A vibrating device for vibrating a cantilevered probe, probe and, Two fixing members that sandwich and support the probe, The system includes a vibration generating unit that applies vibration to at least one of the two fixed members, With the probe sandwiched between the two fixing members, a recess is formed in at least one of the two fixing members at a position corresponding to the probe, where the probe is positioned. A vibrator in which at least one of the two fixing members has a resin portion on the surface facing the probe, and the recess is formed in the resin portion. [Claim 9] The vibration device according to claim 8, wherein the resin part is removable from the fixing member having the resin part. [Claim 10] The vibration device according to claim 1, The system includes a vibration measurement unit that outputs a signal for feedback control of the vibration of the probe, The vibration measurement unit comprises a light emission unit and a light receiving unit that receives light emitted from the light emission unit and reads information regarding the vibration of the probe. A vibration system in which light emitted from the light emitting unit is irradiated onto the probe, and the light irradiated onto the probe is incident on the light receiving unit. [Claim 11] The vibration device according to claim 1, The system includes a vibration measurement unit that outputs a signal for feedback control of the vibration of the probe, The vibration measuring unit is The device comprises a light-emitting unit, a light-receiving unit that receives light emitted from the light-emitting unit and reads information regarding the vibration of the probe, and a plurality of mirrors. The portions of the light-emitting section and the light-receiving section located on the tip side of the probe are located behind the tip of the probe. A vibration system in which light emitted from the light emitting unit is irradiated onto the probe via at least one mirror, and the light irradiated onto the probe is reflected by at least one mirror and incident on the light receiving unit. [Claim 12] A vibrating device for vibrating a cantilevered probe, A probe with an axial shape, In a first direction perpendicular to the axial direction, the probe is supported by being sandwiched between first and second fixing members, The device comprises a vibration generating unit that applies vibration to at least one of the first and second fixing members, With the probe sandwiched between the first and second fixing members, a recess is formed in the first fixing member along its entire axial direction. The probe is positioned across the entire recess, The recess is a vibration device that cooperates with the first fixing member to restrict the movement of the probe in the axial direction and in a second direction perpendicular to the first direction, A liquid supply device that supplies liquid to the probe, The system comprises an electrode portion for charging the aforementioned liquid, The probe has a channel through which liquid flows, The liquid supply device is an extraction-ionization system connected to one end of the probe. [Claim 13] The vibration device according to claim 6, A liquid supply device that supplies liquid to the probe, An electrode portion for charging the aforementioned liquid, It comprises a filter unit that removes foreign matter contained in the liquid, The filter section is an extraction-ionization system positioned between the electrode section and the probe. [Claim 14] The extraction-ionization system according to claim 13, wherein the filter unit and the probe are connected without a tube. [Claim 15] The extraction-ionization system according to claim 13, wherein the filter unit is incorporated into a part of the flow path formed in the probe. [Claim 16] The extraction-ionization system according to claim 13, wherein a part of the channel formed in the probe is filled with fine particles as the filter portion. [Claim 17] The extraction-ionization system according to claim 16, characterized in that the fine particles have a chemical bond with the surface of the channel. [Claim 18] The extraction-ionization system according to claim 16, characterized in that the fine particles have an amino group on their surface. [Claim 19] The extraction-ionization system according to claim 16, characterized in that the fine particles are based on silica gel. [Claim 20] A vibrator that vibrates a cantilevered probe, A liquid supply device that supplies liquid to the probe, An extraction-ionization system comprising an electrode section for charging the aforementioned liquid, The aforementioned vibration device is A probe having a channel through which liquid passes, Two fixing members that sandwich and support the probe, The system includes a vibration generating unit that applies vibration to at least one of the two fixed members, With the probe sandwiched between the two fixing members, a recess is formed in at least one of the two fixing members at a position corresponding to the probe, where the probe is positioned. The extraction-ionization system is, The system includes a filter unit that removes foreign matter contained in the liquid, The filter section is positioned between the electrode section and the probe. An extraction-ionization system in which isolated microparticles are packed into a portion of the channel formed in the probe. [Claim 21] An extraction-ionization system according to any one of claims 12 to 20, A mass spectrometry system comprising a mass spectrometer. [Claim 22] A vibration method for vibrating a cantilevered probe, With the probe sandwiched between two fixing members, the probe is supported by the two fixing members such that the probe is positioned across the entire recess formed along the entire axial direction of the probe at a position corresponding to the probe on at least one of the two fixing members, The step of applying vibration to one of the two fixed members is included, The probe comprises a first end which is the end of the main body, a second end which is the opposite end of the main body to the first end, and the main body between the first end and the second end. A vibration method in which the two fixing members support the portion of the main body near the first end by sandwiching it in a first direction perpendicular to the axial direction.

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