Composition having enhanced d-tagatose plant-blight-controlling effect and rain resistance

Abstract

The present invention addresses the problem of providing a plant-blight-controlling composition having enhanced D-tagatose potency and improved rain resistance, and also providing a method for controlling plant blight using the composition.　The present invention is a plant-blight-controlling composition that contains D-tagatose as an active ingredient, an oil component, and a surfactant, the plant-blight-controlling composition being effective against plant blight, particularly blight caused by fungi and blight caused by bacteria.

Description

Composition with enhanced plant disease control effect and rain resistance of D-tagatose

[0001] The present invention relates to a plant disease control composition comprising D-tagatose as an active ingredient, which is blended with an oil component and a surfactant to enhance the plant disease control effect and rain resistance of the active ingredient, and to a plant disease control method using the composition.

[0002] Pesticides are used in agricultural production to control crop diseases, pests, and weeds, reduce agricultural labor, and stabilize the quality and yield of agricultural products. They are essential to modern agriculture in ensuring safe and secure agricultural products. Pesticides include herbicides, insecticides, fungicides, plant growth regulators, etc. Furthermore, fungicides, i.e., plant disease control agents, are used for the purpose of disease control. However, frequent and excessive use of fungicides with the same action properties to target specific plant diseases can lead to the development of fungicide resistance in the target plant pathogens.

[0003] On the other hand, in recent years, there has been growing consumer interest in crops using reduced amounts of pesticides, and social interest in reducing the environmental impact of chemically synthesized pesticides. Under these circumstances, there is a demand for plant disease control agents and plant disease control methods that have less environmental impact than conventional chemically synthesized pesticides, have a broad spectrum of activity against various diseases, and are highly effective against resistant bacteria that are no longer effective against existing fungicides.

[0004] D-tagatose is a monosaccharide classified as a ketose, and is classified as a rare sugar that exists only in trace amounts in nature (Non-Patent Document 1). It has also been declared highly safe by the Food and Drug Administration (FDA) and the World Health Organization (WHO) (Non-Patent Documents 2 and 3), and is used as a food or food additive.

[0005] D-tagatose has been reported to be effective as a plant disease control agent (Patent Document 1, Non-Patent Document 4). For example, it has been shown to be effective in controlling diseases caused by obligate parasitic fungi such as downy mildew (cucumber downy mildew, grape downy mildew, cabbage downy mildew, etc.), powdery mildew (cucumber powdery mildew, etc.), and rust fungi (wheat leaf rust, etc.), as well as diseases caused by oomycetes such as tomato phytophthora and Pythium wilt, demonstrating its usefulness as a plant disease control agent (Patent Document 3, Non-Patent Document 4). It has also been shown that when combined with a specific fungicide component, it exhibits a synergistic control effect against various plant diseases (Patent Document 3).

[0006] It has been revealed that the plant disease control effect of monosaccharides including D-tagatose can be significantly enhanced by combining them with nonionic surfactants, anionic surfactants, cationic surfactants, amphoteric surfactants, water-soluble polymers, amino acids, amino sugars, disaccharide alcohols, or salts, and that these monosaccharides are effective as plant disease control agents (Patent Document 2).

[0007] It is widely known that oil components can be used to enhance the efficacy of pesticides. Pesticides are typically fat-soluble compounds, and dispersing them in oil components can improve their spreading ability, foliar penetration, and local migration during spraying. However, because pesticides can cause phytotoxicity to crops depending on their compatibility with the oil component, there are few examples of their use as OD agents containing oil components. In particular, for oil-based suspension formulations (Oil Dispersion (OD) agents), emulsification by mixing oil and surfactants is important, and it is considered important to find a combination of oil and specific surfactants.

[0008] On the other hand, D-tagatose is a highly water-soluble compound, and in aqueous solution it exists in equilibrium with α-pyranose, β-pyranose, α-furanose, β-furanose, and a linear structure. The effect of enhancing efficacy by mixing highly water-soluble compounds, including chemically synthesized pesticides, with oil components has not been clarified.

[0009] WO2010 / 021121WO2014 / 142074

[0010] International Society of Rare Sugars. http: / / www. isrs.kagawa-u.ac.jp / definition.html (2002).Rulis, A. M. Agency response letter GRAS notice No. GRN 000078.Washington, DC: US ​​Food and Drug Administration: Center for Food Safety and Applied Nutrition: Office of Food Additive Safety. http: / / pages. citebite. com / e2f2x0h3y0tjw (2001).Joint FAO / WHO expert committee on food additives sixty-third meeting.Summary and conclusions. http: / / www.fao.org / 3 / a-at878e.PDF (2004).The rare sugar D-Tagatose protects plants from downy mildews and is a safe fungicidal agrochemical. Commun Biol. 2020 Aug 5;3(1):423.

[0011] It has been shown that the plant disease control effect of monosaccharides, including D-tagatose, can be significantly enhanced by combining them with nonionic surfactants, anionic surfactants, cationic surfactants, amphoteric surfactants, water-soluble polymers, amino acids, amino sugars, disaccharide alcohols, or salts (Patent Document 2). However, it has not been shown whether the enhancement of efficacy or improvement of rain resistance can be achieved by mixing oil components with surfactants.

[0012] There have been no studies or clarifications on combinations of oil components and surfactants that can enhance the efficacy of compositions containing D-tagatose, oil components, surfactants, etc., or that can improve the stability, emulsification properties, and rain resistance of the compositions.

[0013] There have been no studies or studies on the effectiveness or rain resistance of a composition containing D-tagatose as an active ingredient when mixed with an oil component and a surfactant in the garden, and this has not been clarified.

[0014] An object of the present invention is to provide a plant disease control composition having enhanced efficacy of D-tagatose and improved rain resistance, and a plant disease control method using the composition.

[0015] In order to solve the above problems, the present inventors have conducted various studies on combinations of D-tagatose with oil components and surfactants, etc., and have found that by combining D-tagatose with oil components and surfactants, the plant disease control effect of D-tagatose against various plant diseases can be enhanced to an extent that would not be expected from the components alone, and that rain resistance can be enhanced without causing phytotoxicity to plants, thereby completing the present invention.

[0016] The present invention relates to the following compositions (Invention 1) to (Invention 14). (Invention 1) A plant disease control composition comprising D-tagatose, at least one oil component, and at least one surfactant. (Invention 2) The plant disease control composition of Invention 1 above, wherein the oil component is at least one selected from the group consisting of oils and fats, mineral oil, and essential oils. (Invention 3) The plant disease control composition of Invention 2 above, wherein the oil and fat is vegetable oil. (Invention 4) The plant disease control composition of Invention 2 above, wherein the mineral oil is liquid paraffin. (Invention 5) The plant disease control composition of Invention 2 above, wherein the essential oil is at least one selected from the group consisting of orange oil, bergamot oil, and lavender oil. (Invention 6) The plant disease control composition of Invention 3 above, wherein the vegetable oil is at least one selected from the group consisting of soybean oil, rapeseed oil, castor oil, linseed oil, macadamia nut oil, sunflower oil, olive oil, palm oil, and vegetable oil-derived fatty acid methyl-esterified oil (methylated seed oil). (Invention 7) The plant disease control composition of any one of Inventions 1 to 6 above, wherein the surfactant is at least one selected from the group consisting of nonionic surfactants and anionic surfactants. (Invention 8) The plant disease control composition of Invention 7 above, wherein the nonionic surfactant is at least one selected from the group consisting of polyoxyalkylene alkyl ethers, polyoxyalkylene sorbite fatty acid esters, sorbitan fatty acid esters, glycerin fatty acid esters, sucrose fatty acid esters, and polyoxyethylene sorbitan fatty acid esters. (Invention 9) The plant disease control composition according to Invention 7, wherein the anionic surfactant is at least one selected from the group consisting of lignin sulfonate, formalin condensate of aryl sulfonate, polycarboxylate, α-olefin sulfonate, alkyl sulfate, sulfosuccinate, and aryl sulfonate. (Invention 9a) The surfactant is selected from the group consisting of a compound selected from the group consisting of a hydroxyl group represented by the following Table: The plant disease control composition of any one of Inventions 1 to 6 above, which is at least one selected from the group consisting of surfactants Nos. 1 to 45 described in JP 2004-2009666 A1. (Invention 10) The plant disease control composition of any one of Inventions 1 to 9 and 9a above, which is a plant disease control agent for fungal and bacterial diseases. (Invention 11) A plant disease control method comprising applying to a plant the plant disease control composition of any one of Inventions 1 to 9, 9a, and 10 above. (Invention 12) The plant disease control method of Invention 11 above, wherein the application to the plant involves contacting the plant disease control composition with the plant body, or contacting the plant roots or rhizomes by including the plant disease control composition in cultivation soil or hydroponic culture solution. (Invention 13) The plant disease control method of Invention 11, wherein application to cultivation soil or a hydroponic culture solution involves treating the soil surface with the plant disease control composition, irrigating the soil, or mixing the composition into the soil, and application to a hydroponic culture solution involves diluting the plant disease control composition in the hydroponic culture solution. (Invention 14) Use of a composition comprising D-tagatose, at least one selected from oil components, and at least one selected from surfactants as a plant disease control agent.

[0017] The plant disease control composition of the present invention, which contains D-tagatose, an oil component, and a surfactant, exhibits enhanced plant disease control effects against various plant diseases compared to D-tagatose alone, does not cause phytotoxicity to plants, and can improve rain resistance. These effects were not even anticipated by those skilled in the art.

[0018] Next, various terms used in this specification will be explained.

[0019] "D-tagatose" in the present invention is a monosaccharide that is a component of polysaccharides and rare sugars, and is classified into hexoses and ketoses depending on its chemical structure and functional group. It is generally in the form of a solid powder, but also includes syrups containing D-tagatose produced by isomerizing isomerized sugar syrup.

[0020] In the present invention, "oil components" refer to "mineral oils," which are mixtures containing hydrocarbon compounds or impurities derived from underground resources such as natural gas and coal, "essential oils," which are volatile oils produced by plants, and "oils and fats," which are glycerin esters of fatty acids derived from animals and plants. "Oils and fats" includes both "animal oils and fats" and "vegetable oils and fats."

[0021] The "surfactant" in the present invention is added to the oil component for the purposes of emulsification, solubilization, dispersion, foaming, wettability, etc., and examples of the "surfactant" include nonionic surfactants, anionic surfactants, cationic surfactants, and amphoteric surfactants.

[0022] In the present invention, "plant disease" refers to abnormal systemic pathological symptoms such as wilting, damping-off, yellowing, dwarfing, and spindly growth in plants such as agricultural crops, flowers, flowering trees, and trees, caused by pathogens, as well as localized pathological symptoms such as spots, leaf wither, mosaic, cirring, branch dieback, root rot, root galls, and galls, i.e., plant diseases. Pathogens that cause "plant diseases" mainly include fungi, bacteria, spiroplasma, phytoplasma, viruses, viroids, parasitic higher plants, and nematodes, and in particular, diseases caused by fungi are called "fungal diseases," and diseases caused by bacteria are called "bacterial diseases."

[0023] "Fungal diseases" account for approximately 80% of pathogens that cause plant diseases. Fungi (pathogens) that cause fungal diseases include Plasmodiophora, Oomycetes, Zygomycetes, Ascomycetes, Basidiomycetes, and Fungi Imperfecti. Examples of the root-loop fungi include Plasmodiophora root-knot fungus, potato powdery scab fungus, and sugar beet root rot fungus; oomycetes include Phytophthora blight, downy mildew, Pythium sp., and Aphanomyces sp.; zygomycetes include Rhizopus sp.; ascomycetes include peach leaf curl fungus, corn leaf blight fungus, rice blast fungus, powdery mildew, anthracnose, Fusarium head blight, Fuji bakanae disease fungus, and sclerotinia rot fungus; basidiomycetes include rust fungi, smut fungi, purple root rot fungus, blast fungus, and sheath blight fungus; and imperfect fungi include Botrytis cinerea, Alternaria sp., Fusarium sp., Penicillium sp., Rhizoctonia sp., and southern blight fungus, but are not limited to these.

[0024] "Bacterial diseases" account for approximately 10% of pathogens that cause plant diseases. Bacteria (pathogens) that cause bacterial diseases include the Proteobacteria phylum, which includes gram-negative bacteria, the Actinobacteria phylum, which includes gram-positive bacteria, and the Firmicutes phylum. For example, within the Proteobacteria phylum, α-proteobacteria include the genus Rhizobium, Ca. Examples of β-proteobacteria include bacteria of the genus Acidovarax, Burkholderia, and Ralstonia; γ-proteobacteria include bacteria of the genus Pseudomonas, Xanthomonas, and Erwinia; Actinobacteria include bacteria of the genus Streptomyces, Clavibacter, and Curtobacterium; and Firmicutes include bacteria of the genus Bacillus and Clostridium, but are not limited to these.

[0025] In the present invention, the term "plant" refers to an organism that is fixed in one place, obtains nutrients from the air and water, and survives by photosynthesis. Specific examples of such organisms include agricultural and horticultural crops such as rice, wheat, barley, corn, grapes, apples, pears, peaches, cherries, persimmons, citrus fruits, soybeans, green beans, strawberries, potatoes, cabbage, lettuce, tomatoes, cucumbers, eggplants, watermelons, sugar beets, spinach, snow peas, pumpkins, sugarcane, tobacco, bell peppers, sweet potatoes, taro, konjac, cotton, sunflowers, tulips, chrysanthemums, and grass. However, such examples are not limited to these.

[0026] The term "plant body" as used herein collectively refers to all parts constituting the aforementioned "plant," including, for example, stems, leaves, roots, seeds, flowers, fruits, etc. The term "seed" as used herein refers to a seed that stores nutrients for the germination of a young plant and is used for agricultural propagation. Specific examples include seeds of corn, soybeans, cotton, rice, sugar beets, wheat, barley, sunflowers, tomatoes, cucumbers, eggplants, spinach, snow peas, pumpkins, sugarcane, tobacco, bell peppers, rapeseed, etc.; seed potatoes such as taro, potato, sweet potato, and konjac; bulbs such as edible lilies and tulips; and seed bulbs such as rakkyo (Japanese radish); as well as genetically modified crops that are produced by artificially manipulating genes and do not naturally occur in nature, such as soybeans, corn, cotton, etc. that have been given herbicide resistance, rice, tobacco, etc. that have been adapted to cold regions, seeds of corn, cotton, etc. that have been given the ability to produce insecticides, and potato tubers, but are not limited to these.

[0027] The "plant disease control composition" in the present invention is a composition that controls "plant diseases" when "plants" become sick due to various pathogens and show abnormal systemic pathological symptoms such as wilting, damping-off, yellowing, dwarfing, and spindly growth, or localized pathological symptoms such as spots, leaf wither, mosaic, leaf curl, branch dieback, root rot, root galls, and bumps.

[0028] Next, the plant disease control composition of the present invention containing D-tagatose, an oil component and a surfactant will be described.

[0029] The plant disease control composition of the present invention may contain, in addition to the active ingredient D-tagatose, other sugars, ranging from monosaccharides, oligosaccharides to polysaccharides, neutral sugars, acidic sugars, amino sugars, sugar alcohols, and their isomers, as needed, as well as at least one or more sugars selected from the following sugars: D- and L-aldoses such as glucose, mannose, allose, altrose, talose, galactose, idose, gulose, ribose, lyxose, xylose, arabinose, erythrose, threose, and glyceraldehyde; D- and L-ketoses such as fructose, psicose, sorbose, xylulose, ribulose, erythrulose, and dihydroxyacetone; D- and L-polytols such as glucitol, mannitol, altritol, and thiamin; Examples of sugars include, but are not limited to, ritol, iditol, gulitol, allitol, galactitol, arabitol, xylitol, ribitol, erythritol, glycerin, maltitol, lactitol, inositol, and quercitol; disaccharides such as sucrose, maltose, lactose, cellobiose, trehalose, and palatinose; trisaccharides such as raffinose, panose, melezitose, and gentianose; and tetrasaccharides such as stachyose.

[0030] Any "oil component" can be used in the plant disease control composition of the present invention. Specific examples of mineral oils include, but are not limited to, paraffinic solvents such as liquid paraffin, paraffin, isoparaffin, petrolatum, and ceresin; naphthenic solvents; and aromatic hydrocarbon solvents such as xylene, alkylbenzene, naphthalene, alkylnaphthalene, and phenylxylylethane. Essential oils include, but are not limited to, orange oil, turpentine oil, peppermint oil, bergamot oil, lavender oil, lemon oil, tea tree oil, clove oil, coriander oil, citronella oil, thyme oil, rose oil, vetiver oil, hop oil, lemongrass oil, and rosemary oil. Oils and fats include, but are not limited to, animal fats and vegetable fats. Animal fats and fats include, but are not limited to, fish oils (whale oil, shark oil, liver oil, etc.), beef tallow, lard, and milk fat. Vegetable oils include, but are not limited to, olive oil, palm oil, castor oil, soybean oil, rapeseed oil, macadamia nut oil, corn oil, sunflower oil, coconut oil, cocoa oil, jojoba oil, linseed oil, rice bran oil, cottonseed oil, sesame oil, peanut oil, germ oil, angelica oil, echium oil, ethiodized oil, shea butter, jatropha oil, camellia oil, neem oil, babassu oil, grape seed oil, hazelnut oil, iodized oil, tung oil, perilla oil, walnut oil, leaf oil, algae oil, mustard oil, salad oil, unsaturated fatty acids, and vegetable-derived fatty acid methyl ester oil (methylated seed oil). Mineral oils, oils (especially vegetable oils), and essential oils are preferred from the viewpoint of enhancing plant disease control effects and improving rain resistance.

[0031] The "fatty acid methyl-esterified oil derived from vegetable oil (methylated seed oil, hereinafter also referred to as "MSO")" of the present invention refers to an oil in which fatty acids contained in vegetable oil have been methyl-esterified or esterified, and includes oils in which fatty acids contained in vegetable oils have been methyl-esterified or esterified, such as the aforementioned soybean oil and rapeseed oil, which are examples of vegetable oils derived from vegetable oils. Examples include methyl-esterified rapeseed oil and esterified rapeseed oil, methyl-esterified soybean oil and esterified soybean oil, methyl-esterified coconut oil and esterified coconut oil. Specific examples of MSO include MES-100 manufactured by Drexel Corporation, STEPAN C-25, STEPAN C-42, STEPAN C-65, STEPOSOL ME, STEPOSOL SB, STEPOSOL ROE-W manufactured by Stepan Corporation, and RCM-101 manufactured by The Nisshin Oillio Group, Ltd., but are not limited to these.

[0032] The oil component is preferably one that has fluidity at room temperature, and from the viewpoint of enhancing the plant disease control effect and improving rain resistance, more preferred examples include liquid paraffin, orange oil, bergamot oil, lavender oil, soybean oil, rapeseed oil, castor oil, linseed oil, macadamia nut oil, sunflower oil, olive oil, MSO, and palm oil, and even more preferred examples include liquid paraffin, soybean oil, and MSO, but are not limited to these.

[0033] In the plant disease control composition of the present invention, two or more of the above oil components may be used in combination.

[0034] In the plant disease control composition of the present invention, any nonionic surfactant can be used as the surfactant. Specific examples include acetylene glycol surfactants, fluorine-based surfactants, silicone-based surfactants, polyoxyalkylene alkyl ethers such as POE ether-type nonionic surfactants [polyoxyethylene alkyl ethers (POE oleyl ether, POE alkyl ether (C12-14.2), POE alkyl ether (C12-C13) etc.), polyoxyethylene castor oil ether, polyoxyethylene hydrogenated castor oil ether etc.], polyoxyalkylene alkylamines (polyoxyethylene alkylamines, polyoxyethylene fatty acid amides etc.), alkyl polyglycosides (decyl polyglucosides etc.), polyoxyalkylene aryl ethers (polyoxyethylene styryl phenyl ether, polyoxyethylene alkylphenol, polyoxyalkylene styryl phenyl ether, polyoxyethylene benzyl phenyl ether, polyoxyalkylene benzyl phenyl ether, polyoxyethylene styryl phenyl ether formalin condensate, polyoxyethylene dialkylphenyl ether, polyoxyethylene alkylphenyl ether formalin condensate, etc.), glycerin fatty acid esters (glycerin monopalmitate, glycerin mono- or distearate, glycerin monobehenate, glycerin mono-12-hydroxystearate, glycerin mono- or dioleate, glycerin mono- or dicaprylate, glycerin mono- or dicaprate, glycerin mono- or dilaurate, glycerin mono- or distearate, glycerin Fatty acid mono- or diglycerides such as serine mono- or dipalmitate, glycerin mono- or dibehenate, glycerin mono- or dioleate, glycerin diacetomonolaurate, and glycerin diacetomonooleate; glycerin organic acid fatty acid esters such as acetate fatty acid monoglyceride, citrate fatty acid monoglyceride, succinate fatty acid monoglyceride, lactate fatty acid monoglyceride, and diacetyltartarate fatty acid monoglyceride; acetylated monoglycerides; medium-chain fatty acid triglycerides;etc.), polyglycerin fatty acid esters (diglycerin monostearate, diglycerin monolaurate, diglycerin monomyristate, diglycerin monostearate, diglycerin monooleate, tetraglycerin stearate, decaglycerin laurate, polyglycerin polyricinoleate etc.), propylene glycol fatty acid esters (propylene glycol monolaurate, propylene glycol monopalmitate, propylene glycol monostearate, propylene glycol monooleate etc.), polyoxyalkylene sorbitan fatty acid esters [polyoxyethylene sorbitan fatty acid esters (POE sorbitan fatty acid esters), for example, polyoxyethylene sorbitan tetraoleate etc.], sorbitan fatty acid esters (sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, sorbitan tristearate, sorbitan monooleate etc.), polyoxyethylene sorbitan fatty acid esters (polyoxyethylene sorbitan monolaurate, polyoxyethylene sorbitan Examples of suitable olefin copolymers include olefin monostearate, polyoxyethylene sorbitan tristearate, polyoxyethylene sorbitan oleate, polyoxyethylene sorbitan trioleate, polyoxyethylene sorbitan monopalmitate, polyoxyethylene sorbitol hexaoleate, etc.), sucrose fatty acid esters (sucrose mono- or dicaprate, sucrose mono- or dilaurate, etc.), polyoxyalkylene fatty acid esters (polyoxyethylene monolaurate, polyoxyethylene distearate, polyoxyethylene fatty acid esters, polyoxyethylene resin acid esters, polyoxyethylene fatty acid diesters, etc.), polyoxyethylene polyoxypropylene block polymers (polyoxyethylene polyoxypropylene block polymers, alkyl polyoxyethylene polyoxypropylene block polymer ethers, alkylphenyl polyoxyethylene polyoxypropylene block polymer ethers, etc.), polyoxyethylene fatty acid bisphenyl ethers, fatty acid diethanolamides, and alkyl imidazolines.

[0035] Preferred examples of nonionic surfactants include polyoxyalkylene alkyl ethers such as polyoxyethylene hydrogenated castor oil ether (POE hydrogenated castor oil) and polyoxyethylene castor oil ether (POE castor oil), polyoxyalkylene sorbite fatty acid esters (particularly polyoxyethylene sorbite fatty acid esters (POE sorbite fatty acid esters)), sorbitan fatty acid esters, glycerin fatty acid esters, sucrose fatty acid esters and polyoxyethylene sorbitan fatty acid esters (POE sorbitan fatty acid esters), and POE ether-type nonionic surfactants, but are not limited to these.

[0036] In the plant disease control composition of the present invention, two or more of the above nonionic surfactants may be used in combination.

[0037] In the plant disease control composition of the present invention, any anionic surfactant can be used as the surfactant. Specifically, lignin sulfonates (such as sodium lignin sulfonate), aryl sulfonates (such as alkylbenzene sulfonates such as sodium dodecylbenzene sulfonate; alkylnaphthalene sulfonates such as sodium alkylnaphthalene sulfonate, sodium monoalkylnaphthalene sulfonate, or sodium dialkylnaphthalene sulfonate; etc.), formalin condensates of aryl sulfonates (such as naphthalene sulfonate formalin condensate salts such as naphthalene sulfonate formalin condensate sodium salt; alkylnaphthalene sulfonate formalin condensate salts such as alkylnaphthalene sulfonate formalin condensate sodium salt; phenolsulfonate formalin condensate salts such as phenolsulfonate formalin condensate sodium salt; etc.), α-olefin sulfonates (such as sodium α-olefin sulfonate), alkyl sulfonates (such as sodium alkyl sulfonate), Alkyl diphenyl ether disulfonates (such as sodium alkyl diphenyl ether disulfonate), polyoxyethylene alkyl phenyl ether sulfonates (such as sodium polyoxyethylene alkyl phenyl ether sulfonate), polyoxyethylene alkyl ether sulfosuccinate half esters, alkyl sulfates (such as sodium lauryl sulfate), sulfosuccinates (dialkyl sulfosuccinates, for example, sodium dialkyl sulfosuccinate), polyoxyalkylene aryl ether sulfates (polyoxyethylene alkyl aryl ether sulfate, polyoxyethylene styryl phenyl ether sulfate, polyoxyethylene benzyl phenyl ether sulfate, polyoxyalkylene styryl phenyl ether sulfate), polyoxyalkylene alkyl ether sulfates (polyoxyethylene alkyl ether sulfates such as polyoxyethylene lauryl ether sulfate);etc.), polyoxyethylene polyoxypropylene block polymer sulfates (such as polyoxyethylene polyoxypropylene block polymer sodium sulfate), polyoxyalkylene alkyl ether acetates (such as polyoxyethylene alkyl ether acetates such as polyoxyethylene lauryl ether acetate sodium salt; etc.), polyoxyalkylene aryl ether phosphates (such as polyoxyethylene styrenated phenyl ether phosphate, polyoxyethylene styryl phenyl ether phosphate, polyoxyethylene benzyl phenyl ether phosphate, polyoxyethylene alkyl phenyl ether phosphate), polyoxyalkylene alkyl ether phosphates (such as polyoxyethylene lauryl ether monophosphate ethanolamine salts, polyoxyethylene lauryl ether phosphate esters, etc.), polyoxyethylene polyoxypropylene block polymer phosphates (polyoxyethylene polyoxypropylene block polymer sodium phosphate, etc.), alkyl phosphate esters (alkyl phosphoric acid, sodium alkyl phosphate, etc.), methyl taurate salts (sodium oleyl methyl tauride, etc.), polycarboxylates (sodium polycarboxylate, sodium alkylene maleate copolymer, maleic acid isobutylene copolymer, acrylic acid maleate copolymer sodium, polycarboxylate sodium distyrylphenyl ether sulfate ammonium salt, etc.), and fatty acid salts (semi-hardened beef tallow fatty acid soda soap, etc.);

[0038] Preferred examples of the anionic surfactant include lignin sulfonates, aryl sulfonates, formalin condensates of aryl sulfonates, polycarboxylates, α-olefin sulfonates, alkyl sulfates, and sulfosuccinates, more preferred examples include sulfosuccinates, alkyl sulfates, and aryl sulfonates, and even more preferred examples include dialkyl sulfosuccinates, sodium lauryl sulfate, and alkylbenzene sulfonates, but are not limited to these.

[0039] In the plant disease control composition of the present invention, two or more of the above-mentioned anionic surfactants may be used in combination.

[0040] In the plant disease control composition of the present invention, any cationic surfactant and / or any amphoteric surfactant can be used as the surfactant, such as polyoxyethylene alkylamine, polyalkylene oxide-modified heptamethyltrisiloxane, tetrasiloxane, or glycerin fatty acid ester.

[0041] In the plant disease control composition of the present invention, the surfactant may be a combination of two or more surfactants selected from the group consisting of the above-mentioned nonionic surfactants, anionic surfactants, cationic surfactants, and amphoteric surfactants. For example, an anionic / nonionic surfactant blend can be used.

[0042] The plant disease control composition of the present invention may contain only the above-mentioned D-tagatose, oil component, and surfactant, but if necessary, solvents, antisettling agents, antifoaming agents, antifreezing agents, antioxidants, dispersion stabilizers, antifungal agents, and thickeners that are commonly added to agricultural formulations can also be added.

[0043] Examples of the solvent include nitrogen-containing compounds such as N-methylpyrrolidone, N-butylpyrrolidone, and 1,3-dimethyl-2-imidazolidinone; alcohols such as methanol, ethanol, 1-propanol, and 2-ethylhexanol; ethers such as 1,4-dioxane, diethyl ether, and tetrahydrofuran; ketones such as acetone and ethyl methyl ketone; and esters such as methyl lactate, ethyl acetate, and benzyl acetate.

[0044] Examples of anti-settling agents include silica, hydrophobic fumed silica, organic bentonite, bentonite, and aluminum magnesium silicate.

[0045] Examples of the antifoaming agent include alcohols such as isooctadecanol, and methylated silicone.

[0046] Examples of antifreezing agents include polyhydric alcohols such as ethylene glycol, diethylene glycol, propylene glycol, and glycerin.

[0047] Examples of antifungal agents include sodium benzoate, potassium sorbate, 1,2-benzisothiazolin-3-one, and ethylparaben.

[0048] Thickeners include calcium stearate.

[0049] However, these components are not limited to the above examples.

[0050] In the present invention, the blending ratio of each component cannot be generally defined because it may vary appropriately depending on the type of blended component, formulation form, application scene, etc., but for example, D-tagatose is 1 to 50 parts by weight, preferably 5 to 40 parts by weight, the oil component is 10 to 98.89 parts by weight, preferably 30 to 93.9 parts by weight, and the surfactant is 0.01 to 30 parts by weight, preferably 0.1 to 20 parts by weight. If the surfactant is a nonionic surfactant, the blending ratio is more preferably 0.1 to 30 parts by weight, even more preferably 1 to 20 parts by weight, and if the surfactant is an anionic surfactant, the blending ratio is more preferably 0.01 to 10 parts by weight, even more preferably 0.1 to 5 parts by weight.

[0051] In the present invention, in addition to using the plant disease control composition containing D-tagatose, an oil component, and a surfactant, a composition containing D-tagatose as an active ingredient and a composition containing an oil component and a surfactant can be used simultaneously or separately. When used separately, either the composition containing D-tagatose as an active ingredient or the composition containing an oil component and a surfactant may be used first, followed by the other composition, and the order of use is optional. Alternatively, the composition containing D-tagatose as an active ingredient, the composition containing an oil component, and the composition containing a surfactant can be used simultaneously or separately. When used separately, these compositions can be used in any order. The same applies to the mixed use of commercially available wetting agents containing oil components. That is, the present invention also relates to a method for improving the plant disease control effect and rain resistance of D-tagatose, which comprises simultaneously or separately applying D-tagatose, at least one oil component, and at least one surfactant to a plant.

[0052] To improve rain resistance, a formulation containing D-tagatose (for example, the tagatose wettable powder formulation used in the examples) is mixed with a composition containing an oil component and a surfactant (for example, a commercially available pesticide or spreader) so that the ratio of D-tagatose to oil component is 1:0.1 to 10, preferably 1:0.5 to 3, more preferably 1:0.5 to 1, and particularly preferably 1:0.5 or 1: 1. In particular, it is preferable that the composition contains liquid paraffin or an esterified or methyl-esterified vegetable oil (for example, MSO such as methyl-esterified rapeseed oil or esterified rapeseed oil) as the oil component.

[0053] Commercially available pesticides and spreading agents containing an oil component and a surfactant that can be used in the present invention include Melo®, Mero®, Tipo®, Vazyl / Oleo®, Vegol®, Purespray®, Puperior 70 Oil®, Parka®, Enspray 99®, Iharol®, Prime Oil®, Agri-Dex®, Crop Oil Concentrate®, Drop Zone®, FSCOC Supreme, Herbimax®, Peptoil, Superb HC, Destiny, Dyne-Amic, FS MSO Ultra, Meth Oil, MSO / MVO, Prime Oil EV, Rivet, Soy Dex Plus, Vegetable Oil, Vegetoil, Superb HC, Biotrol, Oil Chemag extend, Chemtrol, Codacide(R), Ecotrol, Endorse, Envoy, Intac, Miller exit, Nextmspray Adjuvant, Nuturf® Driftex, ProCanoil spray oil, Protec® oil, Rutec Control Oil, Sacoa Xseed, Simplot Oil, Smart Crop spray oil, Spalding canola oil spray oil conc, Spraytech oil, Stoller natur'l oil, Supa stick, Synertrol®, Xtend Plant oil, Activoil, Addigor®, Bolster, Dasher, Effectiveoil, Fastuptm, Glysarin 704, Hasten®, Impel, Infiltrator, Kwickin®, Phase Dispersant Penetrant, Plantocrop, Promax, Pronto,Examples of suitable oils include, but are not limited to, Protec (registered trademark) Plus, Racer ultra, Rapid oil, Rocket (registered trademark), Swift, Synertrol (registered trademark) excel, Trio sterycon oil 700, 4-Farmers speedy, saf oil emulsion, kumiaiataku oil, harvest oil, and machine oil.

[0054] Next, a method for controlling plant diseases using the plant disease control composition of the present invention containing D-tagatose, an oil component, and a surfactant will be described.

[0055] Methods for applying the plant disease control composition of the present invention include contacting the plant disease control composition with plant bodies such as seeds, or contacting the roots or rhizomes of plants by incorporating the composition into cultivation soil or hydroponic culture solution, etc., i.e., specific methods include spraying the plant disease control composition on the stems and leaves of individual plants, treatment with seedling trays, spraying on the soil surface, soil incorporation after spraying on the soil surface, injection into the soil, soil incorporation after injection into the soil, soil drench, soil incorporation after drench, dilution in hydroponic culture solution, spraying on plant seeds, smearing on plant seeds, dipping on plant seeds, and dressing on plant seeds, but any of the application methods normally used by those skilled in the art will be sufficiently effective.

[0056] Specifically, the present invention relates to a method for controlling plant diseases, which comprises applying a plant disease control composition to a plant; the method, in which the application to the plant involves bringing the plant disease control composition into contact with the plant body, or incorporating the composition in cultivation soil or a hydroponic culture solution and thereby bringing the composition into contact with the roots or rhizomes of the plant; and the method, in which the application to cultivation soil involves treating the soil surface with the plant disease control composition, irrigating the soil, or incorporating the composition into the soil, and the application to the hydroponic culture solution involves diluting the plant disease control composition in the hydroponic culture solution.

[0057] The application rate and application concentration of the plant disease control composition of the present invention vary depending on the target crop, target disease, disease incidence, compound formulation, application method, and various environmental conditions. However, when spraying or irrigating, a suitable treatment amount of D-tagatose is 50 to 1,000,000 g per hectare, preferably 100 to 500,000 g per hectare. Furthermore, when seed treatment is performed, the amount of D-tagatose used is 0.001 to 50 g, preferably 0.01 to 10 g, per kg of seeds. When the plant disease control composition of the present invention is used for foliar spray treatment on plant individuals, soil surface spray treatment, soil injection treatment, soil drench treatment, or dilution in a hydroponic culture solution, it may be diluted to an appropriate concentration in a suitable carrier prior to treatment. When the plant disease control composition of the present invention is brought into contact with plant seeds, it may be diluted to an appropriate concentration and then used by immersion, dust coating, spraying, or smearing the plant seeds. The amount of the formulation used in the case of coating, spraying, or smearing treatment is usually about 0.05 to 50%, more preferably 0.1 to 30%, of the weight of the dried plant seeds as the amount of D-tagatose used. However, such amounts are not limited to these ranges and may vary depending on the form of the formulation and the type of plant seeds to be treated.

[0058] The plant disease control composition of the present invention is effective against the following types of plant diseases. Specific diseases and their pathogens are listed below, but the present invention is not limited to these.

[0059] Magnaporthe grisea, Thanatephorus cucumeris, Ceratobasidium setariae, Waitea circinata, Thanatephorus cucumeris, Sclerotinia hydrophilum, Waitea circinata, Entyloma dactylidis, Magnaporthe grisea salvinii)、Ceratobasidium cornigerum)、Cochalbasidium miyabeaanus)、Sphaerulinus oryzias)、Goma leaf blight)、Gibberella fujikuroi)、Seedling damping-off disease)、Pythium spp.、Fusariuum spp.、Trichoderma spp.、Rhizopus spp.、Rhizoctonia solanini、Mucor sp.)、Seedling rot disease)、Pythium rot spp., Achlya spp., Dictyuchus spp.), Claviceps virens, Tilletia barclayana, Brown rice (Curvularia spp., Alternaria spp.), Yellowing shriveling disease (Sclerophthora macrospora), Bacterial leaf blight (Xanthoma oryzae pv. oryzae), Brown streak disease (Acidovoraxa avenae subsp.). avenae), Erwinia ananas, Burkholderia plantaria, Burkholderia glumae, Pseudomonas fuscovaginae, Pseudomonas syringae prv. oryzae, Erwinia chrysanthemum, Verticillium wilt, Rice stripe tenuivirus), atrophy disease (Rice dwarf reovirus);

[0060] Blumeria graminis f.sp.hordei; f. Puccinia graminis, Puccinia recondita, Puccinia hordei), leaf spot (Pyrenophora) graminea, Pyrenophora teres), red かび disease (Gibberella zeae, Fusarium culmorum、fusarium avenaceum, Monographella nivalis, snow rot (Typhula) incarnata、Typhula ishikariensis, Monographella nivalis), Ustilago nuda, Naked Kuro disease (Tiletia) caries, Tilletia controversa), Pseudocercosporella herpotricular rot (Ceratobasidium graminiuneum), cloud-shaped disease (Rhynchosporium secalis), leaf blight (Septoria tritici), seedling blight (Phaeosphhaeeria nodorum), seedling damping-off (Fusarium spp., Pythium spp., Rhizoctonia spp., Septoriia spp., Pyrenophora spp.), damping-off (Gaeumannnomyces graminis), anthrax (Colletotrichum graminis), ergot (Claviceps purpururea), leaf spot (Cochliobolus sativus), black knot (Pseudomonas syringae pv. syringae);

[0061] Corn head blight (Gibberella zeae, etc.), seedling damping-off (Fusarium avenaceum, Penicillium spp., Pythium spp., Rhizoctonia spp.), rust (Puccinia sorghi), southern leaf blight (Cochliobolus heterostrophus), ear smut (Ustilago maydis), anthracnose (Colletotrichum graminicola), northern leaf spot (Cochliobolus carbonum), brown stripe (Acidovorax avenae subsp. avenae), bacterial streak (Burkholderia andropogonis), bacterial lodging (Erwinia chrysanthemi pv. zeae), bacterial wilt (Erwinia stewartii); grape downy mildew (Plasmopara viticola), rust (Physopella ampelopsidis), powdery mildew (Uncinula necator), black rot (Elsinoe ampelina), late rot (Glomerella cingulata, Colletotrichum acutatum), black rot (Guignardia bidwellii), Fusarium wilt (Phomopsis viticola), Sooty spot (Zygophiala jamaicensis), Gray mold (Botrytis cinerea), Shoot blight (Diaporthe medusaea), Purple root rot (Helicobasidium mompa), White root rot (Rosellinia necatrix), Crown gall (Agrobacterium vitis);

[0062] Apple powdery mildew (Podosphaera leucotricha), black spot (Venturia inaequalis), leaf spot (Alternaria mali), red spot (Gymnosporangium yamadae), monilia disease (Monilinia mali), canker (Valsa ceratosperma), ring spot (Botryosphaeria berengeriana), anthracnose (Colletotrichum acutatum, Glomerella cingulata), sooty spot (Zygophiala jamaicensis), sooty blotch (Gloeodes pomigena), black spot (Mycosphaerella pomi), purple root rot (Helicobasidium mompa), white root rot (Rosellinia necatrix), canker (Phomopsis mali, Diaporthe tanakae), brown spot (Diplocarpon mali), fire blight (Erwinia amylovora), crown gall (Agrobacterium tumefaciens), hairy root disease (Agrobacterium rhizogenes); black spot of pear (Alternaria kikuchiana), black scab (Venturia nashicola), red spot (Gymnosporangium asiaticum), ring spot (Botryosphaeria berengeriana f.sp. piricola), canker (Phomopsis fukushii), bacterial branch blight (Erwinia sp.), crown gall (Agrobacterium tumefaciens), rust canker (Erwinia chrysanthemi pv. chrysanthemi), bacterial blossom rot (Pseudomonas syringae pv. syringae); pear blight (Phytophthora cactorum, Phytophthora syringae), bacterial branch blight (Erwinia sp.);Peach black scab (Cladosporium carpophilum), Phomopsis rot (Phomopsis sp.), Late blight (Phytophthora sp.), Anthracnose (Colletotrichum gloeosporioides), Leaf curl (Taphrina deformans), Bacterial perforation (Xanthomonas campestris pv. pruni), Crown gall (Agrobacterium tumefaciens); cherry anthracnose (Glomerella cingulata), Young fruit sclerotinia (Monilinia kusanoi), Brown rot (Monilinia fructicola), crown gall (Agrobacterium tumefaciens), resin bacterium (Pseudomonas syringae pv. syringae); persimmon anthracnose (Glomerella cingulata), leaf spot (Cercospora kaki; Mycosphaerella nawae), powdery mildew (Phyllactinia kakikora), crown gall (Agrobacterium tumefaciens); citrus black spot (Diaporthe citri), green mold (Penicillium digitatum), blue mold (Penicillium italicum), common scab (Elsinoe fawcettii), brown rot (Phytophthora citrophthora), canker (Xanthomonas campestris pv. citri), brown spot bacterial disease (Pseudomonas syringae pv. syringae), greening disease (Liberibacter asiaticus), crown gall (Agrobacterium tumefaciens);

[0063] Gray mold (Botrytis cinerea) of tomatoes, cucumbers, beans, strawberries, potatoes, cabbage, eggplant, lettuce, etc.; Sclerotinia sclerotiorum of tomatoes, cucumbers, beans, strawberries, potatoes, rapeseed, cabbage, eggplant, lettuce, etc.; damping-off of various vegetables such as tomatoes, cucumbers, beans, radishes, watermelons, eggplants, rapeseed, peppers, spinach, and sugar beets (Rhizoctonia spp., Pythium spp., Fusarium spp., Phythophthora spp., Sclerotinia sclerotiorum, etc.); bacterial wilt of Solanaceae plants (Ralstonia solanacearum); cucurbit downy mildew (Pseudoperonospora cubensis), powdery mildew (Sphaerotheca fuliginea), anthracnose (Colletotrichum orbiculare), vine blight (Didymella bryoniae), vine wilt (Fusarium oxysporum), late blight (Phytophthora parasitica, Phytophthora melonis, Phytophthora nicotianae, Phytophthora drechsleri, Phytophthora capsici, etc.), brown spot bacterial disease (Xanthomonas campestris pv. cucurbitae), soft rot (Erwinia carotovora subsp. carotovora), bacterial spot disease (Pseudomonas syringae pv. lachrymans), bacterial edge rot (Pseudomonas marginalis pv. marginalis), canker (Streptomyces sp.), hairy root disease (Agrobacterium rhizogenes), cucumber mosaic virus;Tomato target spot (Alternaria solani), leaf mold (Fulvia fulva), late blight (Phytophthora infestans), fusarium wilt (Fusarium oxysporum), root rot (Pythium myriotylum, Pythium dissotocum), anthracnose (Colletotrichum gloeoosporioides), bacterial canker (Clavibacter michiganensis), angular leaf spot (Pseudomonas corrugata), black spot (Pseudomonas viridiflava), soft rot (Erwinia carotovora subsp. carotovora), leaf knot (Cryanobacterium sp.), aster yellows (Phytoplasma asteris), tomato yellow leaf curl subgroup III geminivirus; Eggplant powdery mildew (Sphaerotheca fuliginea etc.), sooty mold (Mycovellosiella nattrassii), late blight (Phytophthora infestans), brown rot (Phytophthora capsici), brown spot (Pseudomonas cichorii), angular leaf spot (Pseudomonas corrugata), stem rot (Erwinia chrysanthemi), soft rot (Erwinia carotovora subsp. carotovora), spot (Pseudomonas sp.);

[0064] Alternaria brassicae, black rot (Xanthomonas campestris pv. campestris), Pseudomonas syringae pv. maculicola, soft rot (Erwinia carotovora); Alternaria brassicae etc. of cruciferous vegetables, Cercosporella brassicae, Phoma lingam, clubroot (Plasmodiophora brassicae), downy mildew (Peronospora parasitica), black rot (Xanthomonas campestris pv. campestris), Pseudomonas syringae pv. maculicola, soft rot (Erwinia carotovora subsp. carotovora); Thanatephorus cucumeris of cabbage, Fusarium oxysporum; Rhizoctonia solani of Chinese cabbage, Verticillium dahliae; rust (Puccinia allii), Alternaria porri, Sclerotium rolfsii, Phytophthora porri, Sclerotium cepivorum of onion; Curtobacterium flaccumfaciens of shallot, soft rot (Erwinia carotovora subsp. carotovora), Pseudomonas syringae pv. syringae, Erwinia rhapontici, Burkholderia gladioli, Phytoplasma asteris; soft rot (Erwinia carotovora subsp. carotovora), spring rot (Pseudomonas marginalis pv. marginalis) of garlic;Soybean purple spot (Cercospora kikuchii), black rot (Elsinoe glycines), black spot (Diaporthe phaseolorum), Rhizoctonia root rot (Rhizoctonia solani), stem rot (Phytophthora sojae), downy mildew (Peronospora manshurica), rust (Phakopsora pachyrhizi), anthracnose (Colletotrichum truncatum, etc.), leaf burn (Xanthomonas campestris pv. glycines), bacterial spot (Pseudomonas syringae) pv. glycinea);

[0065] Anthracnose (Colletotrichum lindemuthianum), bacterial wilt (Ralstonia solanacearum), halo blight (Pseudomonas syringae pv. phaseolicola), bacterial brown spot (Pseudomonas viridiflava), and leaf burn (Xanthomonas campestris pv. phaseoli) of common beans; black spot (Mycosphaerella berkeleyi), brown spot (Mycosphaerella arachidis), and bacterial wilt (Ralstonia solanacearum); pea powdery mildew (Erysiphe pisi), downy mildew (Peronospora pisi), bacterial vine blight (Pseudomonas syringae pv. pisi), bacterial vine rot (Xanthomonas campestris pv. pisi); broad bean downy mildew (Peronospora viciae), late blight (Phytophthora nicotianae); potato summer blight (Alternaria solani), black spot (Thanatephorus cucumeris), late blight (Phytophthora infestans), silver scurf (Helminthosporium solani), dry rot (Fusarium oxysporum, Fusarium solani), powdery scab (Spongospora subterranea), bacterial wilt (Ralstonia solanacearum), black leg (Erwinia carotovora subsp. atroseptica), scab (Streptomyces scabies, Streptomyces acidiscabies), soft rot (Erwinia carotovora subsp. carotovora), slimy rot (Crosstridium spp.), ring rot (Clavibacter michiganensis subsp. sepedonicus); damping-off of sweet potato (Streptomyces ipomoeae);Sugar beet brown spot (Cercospora beticola), downy mildew (Peronospora schachtii), black root rot (Aphanomyces cochioides), snake eye disease (Phoma betae), crown gall (Agrobacterium tumefaciens), common scab (Streptomyces scabies), bacterial spot (Pseudomonas syringae pv. aptata);

[0066] Carrot black leaf blight (Alternaria dauci), clubroot (Rhizobacter dauci), crown gall (Agrobacterium tumefaciens), streptomyces scab (Streptomyces spp.), soft rot (Erwinia carotovora subsp. carotovora); strawberry powdery mildew (Sphaerotheca aphanis var. aphanis), late blight (Phytophthora nicotianae, etc.), anthracnose (Glomerella cingulata, etc.), fruit rot (Pythium ultimum), bacterial wilt (Ralstonia solanacearum), bacterial corner spot (Xhanthomonas campestris), bacterial shoot blight (Pseudomonas marginalis pv. marginalis); tea net blight (Exobasidium reticulatum), white spot (Elsinoe leucospila), anthracnose (Colletotrichum theae-sinensis), ring spot (Pestalothiopsis longiseta), red blight (Pseudomonas syringae pv. theae), bacterial canker (Xhanthomonas campestris pv. theicola), witches' broom (Pseudomonas sp.); tobacco red star (Alternaria alternata), powdery mildew (Erysiphe cichoracearum), anthracnose (Colletotrichum gloeosporioides), late blight (Phytophthora nicotianae), wildfire (Pseudomonas syringae pv. tabaci), bacterial yellow blight (Pseudomonas syringae pv. mellea), cavity (Erwinia carotovora subsp. carotovora), damping-off (Ralstonia solanacearum), tobacco mosaic virus; cotton damping-off (Fusarium oxysporum);Sunflower stem rot (Sclerotinia sclerotiorum), corner spot disease (Xanthomonas campestris pv. malvacearum), cavity disease Erwinia carotovora subsp. carotovora), bacterial spot (Pseudomonas syringae pv. helianthi); rose black spot (Diplocarpon rosae), powdery mildew (Sphaerotheca pannosa, etc.), late blight (Phytophthora megasperma), downy mildew (Peronospora sparsa), crown gall (Agrobacterium tumefaciens); chrysanthemum brown spot (Septoria obesa), white rust (Puccinia horiana), late blight (Phytophthora cactorum), bacterial spot (Pseudomonas cichorii), soft rot (Erwinia carotovora subsp. carotovora), crown gall (Agrobacterium tumefaciens), hairy root disease (Agrobacterium rhizogenes), greening disease (Phytoplasma aurantifolia); turf brown patch (Rhizoctonia solani), dollar spot (Sclerotinia homoeocarpa), Curvularia leaf blight (Curvularia sp.), rust (Puccinia zoysiae), Helminthosporium leaf blight (Cochliobolus sp. ), Rhynchosporium secalis, damping-off (Gaeumannomyces graminis), anthracnose (Colletotrichum sp.), snow rot brown small-grain sclerotium (Typhula incarnata), snow rot black small grain sclerotia (Typhula ishikariensis), snow rot large grain sclerotinia (Myriosclerotinia borealis), fairy ring disease (Marasmius orreades etc.), Pythium disease (Pythium aphanidermatum etc.), rice blast (Pyricularia grisea). ;

[0067] The plant disease control composition of the present invention is preferably used to control diseases caused by oomycetes such as various downy mildews and late blight, various powdery mildews, various rust diseases, gray mold, apple scab, and the like, and is particularly useful for controlling cucumber powdery mildew, grape powdery mildew, tomato gray mold, tomato late bright, apple scab, and soybean rust. It is more preferable to use it to control cucumber powdery mildew, grape downy mildew, grape powdery mildew, or tomato late blight, but it is not limited to these.

[0068] The plant disease control composition of the present invention can be mixed or used in combination with other pesticides, such as fungicides, insecticides, miticides, nematicides, herbicides, and plant growth regulators, microbial pesticides, spreading agents, soil conditioners, or fertilizers, as needed.

[0069] Examples of fungicides that can be used in combination with the plant disease control composition of the present invention include phenylamide fungicides, mitosis and cell division inhibitors (MBC fungicides), succinate dehydrogenase inhibitors (SDHI agents), external quinone inhibitors (QoI agents), internal quinone inhibitors (QiI agents), oxidative phosphorylation uncoupling inhibitors, external quinone stigmatellin binding subsite inhibitors (QoSI agents), amino acid biosynthesis inhibitors, protein biosynthesis inhibitors, signal transduction inhibitors, lipid and cell membrane biosynthesis inhibitors, demethylation inhibitors (DMI agents), amine fungicides, 3-ketoreductase inhibitors in C4 demethylation of sterol biosynthesis, squalene epoxidase inhibitors in sterol biosynthesis, cell wall biosynthesis inhibitors, melanin biosynthesis inhibitors, host plant resistance inducers, dithiocarbamate fungicides, phthalimide fungicides, guanidine fungicides, multisite contact-active fungicides, and other fungicides. Examples of insecticides, acaricides, and nematicides to be used in combination include carbamate acetylcholinesterase (AChE) inhibitors, organophosphate acetylcholinesterase (AChE) inhibitors, GABA-gated chloride channel blockers, sodium channel modulators, nicotinic acetylcholine receptor (nAChR) competitive modulators, nicotinic acetylcholine receptor (nAChR) allosteric modulators, and glutamate-gated chloride channel (GluCl) modulators. Examples of such inhibitors include allosteric modulators, juvenile hormone analogs, nonspecific (multi-site) inhibitors, mite growth inhibitors, mitochondrial ATP synthase inhibitors, oxidative phosphorylation uncouplers that disrupt the proton gradient, nicotinic acetylcholine receptor (nAChR) channel blockers, chitin biosynthesis inhibitor type 0, chitin biosynthesis inhibitor type 1, dipteran insect molting inhibitors, ecdysone receptor agonists, mitochondrial electron transport complex III inhibitors, mitochondrial electron transport complex I inhibitors (METI), voltage-dependent sodium channel blockers, acetyl-CoA carboxylase inhibitors, mitochondrial electron transport complex IV inhibitors, mitochondrial electron transport complex II inhibitors, ryanodine receptor modulators, chordotonal organ modulators with unspecified target sites, and other agents.The fungicides, insecticides, acaricides, or nematicides mentioned above may be used in combination of one or more, but the present invention is not limited to these.

[0070] Examples of fungicides include nucleic acid metabolism inhibitors such as benalaxyl, benalaxyl-M or chiralaxyl, furalaxyl, metalaxyl, metalaxyl-M or mefenoxam, oxadixyl, ofurace, hymexazol, octhilinone, bupirimate, dimethirimol, ethirimol, and oxolinic acid; Benomyl, carbendazim, fuberidazole, thiabendazole, thiophanate, thiophanate-methyl, diethofencarb, zoxamide Mitosis and cytotoxic agents such as benzodiazepine, benzophenone, benzocaine, benzoyl benzoate ...Benodanil, Benzovindiflupyr, Bixafen, Boscalid, Carboxin, Fenfuram, Fluopyram, Flutolanil, Fluxapyroxad, Furametpyr, Isofetamide, Isopyrazam, Mepronil, Oxycarboxin succinate dehydrogenase inhibitors (SDHI agents) such as benzodiazepine, penthiopyrad, penflufen, pydiflumetofen, sedaxane, thifluzamide, pyraziflumid, isoflucipram, fluindapyr, inpyrfluxam, pyrapropoyne, and cyclobutrifluram;Azoxystrobin, coumoxystrobin, dimoxystrobin, enoxastrobin, famoxadone, fenamidone, phenaminestrobin, flufenoxystrobin, fluoxastrobin, kresoxim-methyl, mandestrobin, Quinone external inhibitors (QoI agents) such as metominostrobin, orysastrobin, picoxystrobin, pyraclostrobin, pyrametostrobin, pyraoxystrobin, pyribencarb, triclopyricarb, trifloxystrobin, and methyltetraprol: Quinone internal inhibitors (QiI agents) such as Cyazofamid, Amisulbrom, Fenpicoxamid, Florylpicoxamid, etc.; Oxidative phosphorylation uncoupling inhibitors such as Binapacryl, Meptyldinocap, Dinocap, Fluazinam, Ferimzone, etc.; Oxidative phosphorylation and ATP synthase inhibitors such as triphenyltin acetate, triphenyltin chloride, and triphenyltin hydroxide, etc.; ATP transport inhibitors such as Silthiofam; Quinone external stigmatellin binding subsite inhibitors (QoSI agents) such as Ametoctradin;Amino acid biosynthesis inhibitors such as cyprodinil, mepanipyrim, pyrimethanil, etc.; protein biosynthesis inhibitors such as blasticidin-S, streptomycin, kasugamycin, oxytetracycline, etc.; signal transduction inhibitors such as quinoxyfen, proquinazid, fenpiclonil, fludioxonil, chlorzolinate, dimethachlone, iprodione, procymidone, vinclozolin, etc.; lipid and cell membrane biosynthesis inhibitors such as edifenphos, iprobenfos, isoprothiolane, pyrazophos, biphenyl, chloroneb, dicloran, quintozene (PCNB), tecnazene (TCNB), tolclofos-methyl, etridiazole, iodocarb, propamocarb, and prothiocarb; Ergosterol binding inhibitors such as natamycin (pimaricin); Oxysterol binding protein inhibitors such as oxathiapiprolin and fluoxapiprolin;Azaconazole, Bitertanol, Bromuconazole, Cyproconazole, Difenoconazole, Diniconazole, Diniconazole-M, Epoxiconazole, Etaconazole, Fenarimol, Fenbuconazole, Fluquinconazole quinconazole, flusilazole, flutriafol, hexaconazole, imazalil, imibenconazole, ipconazole, metconazole, myclobutanil, nuarimol, oxpoconazole, oxpoconazole fumarate fumarate), pefurazoate, penconazole, prochloraz, propiconazole, prothioconazole, pyrifenox, pyrisoxazole, simeconazole, tebuconazole, tetraconazole, demethylation inhibitors (DMI agents) such as tetraconazole, triadimefon, triadimenol, triflumizole, triforine, triticonazole, mefentrifluconazole, ipfentrifluconazole, etc.;Amine fungicides such as aldimorph, dodemorph, fenpropimorph, tridemorph, fenpropidin, piperalin, and spiroxamine; 3-ketoreductase inhibitors in the C4-demethylation of sterol biosynthesis such as fenhexamid and fenpyrazamine; squalene epoxidase inhibitors in sterol biosynthesis such as pyributicarb, naftifine, and terbinafine; Cell wall biosynthesis inhibitors such as polyoxins, dimethomorph, flumorph, pyrimorph, benthiavalicarb, benthiavalicarb-isopropyl, iprovalicarb, mandipropamid, and valifenalate; melanin biosynthesis inhibitors such as benzophenone, benzophenone-1, benzophenone-2, benzothiazolinone, benzophenone-3, benzothiazolinone ...Dithiocarbamate fungicides such as mancozeb, mancozeb (Mancozeb or Manzeb), maneb (Maneb), metiram (Metiram), propineb (Propineb), thiuram (Thiram), zinc thiazole (zinc thiazole), zineb (Zineb), ziram (Ziram), ferbam (Ferbam), etc.; Captan (Captan), captafol (Captafol), folpet (Folpet), fluorofolpet (Fluorofolpet), etc.; Phthalimide fungicides: guazatine (Guazatine), iminoctadine (Iminoctadine), iminoctadine albesilate (Iminoctadine Guanidine fungicides such as chlorothalonil, dichlofluanid, tolylfluanid, basic copper chloride, copper(II) hydroxide, basic copper sulfate, organic copper compounds, dodecylbenzenesulfonic acid bisethylenediamine copper complex salt [II], multi-site contact-active fungicides such as biethylenediamine copper [II] salt, DBEDC), sulfur, fluorimide, anilazine, dithianon, chinomethionate (or quinomethionate), and methasulfocarb; lupin seedling cotyledon extract (BLAD), citrus fruit extract (extract from Swinglea glutinosa), tea extract (extract from Melaleuca alternifolia), and vegetable oil mixtures (eugenol, Plant extracts such as geraniol, thymol, etc.;Tecloftalam, triazoxide, flusulfamide, diclomezine, cyflufenamid, dodine, flutianil, tebufloquin, validamycins, cymoxanil, picarbutrazox, quinofumelin, aminopyrifen, pyridaclomethyl Pyridachlormethyl, Ipflufenoquin, Dipimethitrone, Flufenoxadiazam, Flumethylsulforim, Fluoxytioconazole, Metarylpicoxamide, Seboctylamine, Chlorinconazide, Flubeneteram, Phosphorous acid Other fungicides such as sodium phosphate, ammonium phosphate, and potassium phosphate; Trichoderma atroviride strain I-1237, strain LU132, strain SC1, strain SKT-1, strain 77B, Trichoderma asperellum strain T34, strain kd, Trichoderma harzianum strain T-22, and Trichoderma virens strain. Trichoderma spp. such as G-41; Clonostachys spp. such as Gliocladium catenulatum strain J1446 and Clonostachys rosea strain CR-7;Coniothyrium minitans strain CON / M / 91-08, Talaromyces flavus strain SAY-Y-94-01, Saccharomyces cerevisae strain LAS02 Bacillus amyloliquefaciens strain QST713, strain FZB24, strain MBI600, strain D747, strain F727, strain AT-332, Bacillus subtilis strain AFS032321, strain Y1336, strain Bacillus spp. such as HAI-0404; microbial bactericides such as Pseudomonas chlororaphis strain AFS009, Streptomyces griseovirides strain K61, and Streptomyces lydicus strain WYEC108, but are not limited to these.

[0071] Insecticides include alanycarb, aldicarb, bendiocarb, benfuracarb, butocarboxim, butoxycarboxim, carbaryl, carbofuran, carbosulfan, ethiofencarb, fenobucarb, formetanate, furathiocarb, isoprocarb, methiocarb, and methomyl. Carbamate acetylcholinesterase (ACE) inhibitors such as methomyl, metolcarb, oxamyl, pirimicarb, propoxur, thiodicarb, thiofanox, triazamate, trimethacarb, XMC (3,5-xylyl methylcarbamate), and xylylcarb; acephate, azamethiphos, azinphos-ethyl, and azinphos-methyl (azinphos-ethyl), cadusafos (cadusafos), chlorethoxyphos (chlorethoxyfos), chlorfenvinphos (chlorfenvinphos), chlormephos (chlormephos), chlorpyrifos (chlorpyrifos), chlorpyrifos-methyl (chlorpyrifos-methyl), coumaphos (coumaphos), cyanophos (cyanophos), demeton-S-methyl (demeton-S-methyl), diazinon (diazinon), dichlorvos (dichlorvos), dicrotophos (dicrotophos), dimethoate (dimethoate), dimethylvinphos (dimethylvinphos), disulfoton(disulfoton), ethyl paranitrophenylthionobenzenephosphonate (O-ethyl O-4-nitrophenyl phenylphosphonothioate), ethion (ethion), ethoprophos (ethoprophos), fanflu, fenamiphos (fenamiphos), fenitrothion (fenitrothion), fenthion (fenthion), fosthiazate (fosthiazate), heptenophos (heptenophos), imicyafos (imiciafos), isofenphos (isofenphos), isopropyl = O- (methoxyaminothiophosphoryl) salicylate, isoxathion (isoxathione), malathion (malathion), mecarbam, methamidophos, methidathion, mevinphos, monocrotophos, naled, omethoate, oxydemeton-methyl, parathion, parathion-methyl, phenthoate, phorate, phosalone, phosmet, phosphamidon, phoxim (phoxim), pirimiphos-methyl, profenofos, propetamphos, prothiofos, pyraclofos, pyridaphenthion, quinalphos, sulfotep, tebupirimfos, temephos, terbufos, tetrachlorvinphos, thiometon, triazophos, trichlorfon (trichlorfon), vamidothioneorganophosphorus acetylcholinesterase (AChE) inhibitors such as vamidothion; cyclic diene organochlorine GABAergic chloride ion channel blockers such as chlordane and endosulfan; phenylpyrazole GABAergic chloride ion channel blockers such as ethiprole and fipronil; acrinathrin, allethrin, bifenthrin, bioallethrin, bioresmethrin, cycloprothrin, cyfluthrin, cyhalothrin (cyhalothrin), cypermethrin, cyphenothrin [(1R)-trans-isomer], deltamethrin, empenthrin [(EZ)-(1R)-isomer], esfenvalerate, etofenprox, fenpropathrin, fenvalerate, flucythrinate, flumethrin, fluvalinate, halfenprox (halfenprox), imiprothrin, kadethrin, permethrin, phenothrin [(1R)-trans-isomer], prallethrin, pyrethrin, resmethrin, silafluofen, tefluthrin, tetramethrin, tetramethrin [(1R)-isomer], tralomethrinpyrethroid sodium channel modulators such as DDT (dichloro-diphenyl-trichloroethane) and methoxychlor; DDT, methoxychlor sodium channel modulators such as acetamiprid, clothianidin, dinotefuran, imidacloprid, nitenpyram, thiacloprid, and thiamethoxam; neonicotinoid nicotinic acetylcholine receptor modulators such as acetamiprid, clothianidin, dinotefuran, imidacloprid, nitenpyram, thiacloprid, and thiamethoxam; nAChR competitive modulators; nicotine nicotinic acetylcholine receptor (nAChR) competitive modulators such as nicotine and nicotine sulfate; sulfoximine nicotinic acetylcholine receptor (nAChR) competitive modulators such as sulfoxaflor; butenolide nicotinic acetylcholine receptor (nAChR) competitive modulators such as flupyradifurone; mesoionic nicotinic acetylcholine receptor (nAChR) competitive modulators such as triflumezopyrim; pyridylidene nicotinic acetylcholine receptor (nAChR) competitive modulators such as flupyrimin; spinetoram spinosyn nicotinic acetylcholine receptor (nAChR) allosteric modulators such as spinetoram and spinosad; glutamatergic chloride ion channel (GluCl) allosteric modulators such as abamectin, emamectin benzoate, lepimectin and milbemectin; hydroprene, kinoprene, methoprene and fenoxycarbJuvenile hormone analogues such as fenoxycarb and pyriproxyfen; methyl bromide, other alkyl halides, chloropicrin, cryolite, sulfuryl fluoride, borax, boric acid, disodium octaborate, sodium borate, sodium metaborate, tartar emetic, dazomet, and sodium carbamate. Other non-specific (multi-site) inhibitors such as metham sodium; chordotonal TRPV channel modulators such as pymetrozine, pyrifluquinazon, and afidopyropene; mite growth inhibitors acting on CHS1 such as clofentezine, diflovidazin, hexythiazox, and etoxazole; proteins found in Bacillus thuringiensis subsp. Israelensis, Bacillus thuringiensis subsp. Aizawai, Bacillus thuringiensis subsp. Kurstaki, Bacillus thuringiensis subsp. Tenebrionis, and Bt crops: Microbial-derived insect midgut membrane disrupting agents such as Cry1Ab, Cry1Ac, Cry1Fa, Cry1A.105, Cry2Ab, Vip3A, mCry3A, Cry3Ab, Cry3Bb, Cry34Ab1 / Cry35Ab1; diafenthiuron, azocyclotin, cyhexatin, fenbutatin oxide, propargite, and tetradifonmitochondrial ATP synthase inhibitors such as tetradifon; oxidative phosphorylation uncouplers that disrupt the proton gradient such as chlorfenapyr, DNOC (dinitro-ortho-cresol), and sulfuramide; nicotinic acetylcholine receptor (nAChR) channel blockers such as bensultap, cartap hydrochloride, thiocyclam, and thiosultap sodium salt; bistrifluron, chlorfluazuron, and diflubenzuron. Chitin biosynthesis inhibitors that act on CHS1, such as diflubenzuron, flucycloxuron, flufenoxuron, hexaflumuron, lufenuron, novaluron, noviflumuron, teflubenzuron, and triflumuron; chitin biosynthesis inhibitor type 1, such as buprofezin; diptera molting inhibitors, such as cyromazine; chromafenozide and halofenozide (halofenozide), methoxyfenozide (methoxyfenozide), tebufenozide, and other skin hormone (ecdysone) receptor agonists; amitraz (amitraz), and other octopamine receptor agonists; hydramethylnon (hydramethylnon), acequinocyl (acequinocyl), fluacrypyrim (fluacrypyrim), bifenazate, and other mitochondrial electron transport chain complex III inhibitors; fenazaquin (fenzaquin), fenpyroximate (fenpyroximate), pyridaben (pyridaben), pyrimidifen (pyrimidifen), tebufenpyradMitochondrial electron transport chain complex I inhibitors such as tebufenpyrad, tolfenpyrad, rotenone, etc.; position-dependent sodium channel blockers such as indoxacarb, metaflumizone, etc.; acetyl CoA carboxylase inhibitors such as spirodiclofen, spiromesifen, spiropidione, spirotetramat, etc.; aluminum phosphide, calcium phosphide, hydrogen phosphide, zinc phosphide, etc. mitochondrial electron transport chain complex IV inhibitors such as calcium cyanide, sodium cyanide, potassium cyanide, etc.; mitochondrial electron transport chain complex II inhibitors such as cyenopyrafen, cyflumetofen, piflubamide, etc.; chlorantraniliprole, cyantraniliprole, cyclaniliprole, flubendiamide, tetraniliprole, etc. Ryanodine receptor modulators such as tetraniliprole; sound organ modulators (target site unspecified) such as flonicamide; GABA-gated chloride ion channel allosteric modulators such as broflanilide, fluxametamide, and isocycloseram;Baculoviruses such as the codling moth Cydia pomonella GV, the false codling moth Thaumatotibia leucotreta GV, the velvet bean caterpillar Anticarsia gemmatalis MNPV, and the cotton bollworm Helicoverpa armigera NPV; nicotinic acetylcholine receptor (nAChR) allosteric modulators - site II such as the GS-omega / kappa HXTX-Hv1a peptide; calcium-activated potassium channel (KCa2) modulators such as acynonapyr; mitochondrial electron transport chain complex III inhibitors such as flometoquin; target site undefined; azadirachtin, benzoximate (benzoximate), phenisobromolate, chinomethionate, dicofol, lime sulfur (CaSx), manzeb, pyridalyl, sulfur, bromopropylate, Burkholderia spp., Wolbachia pipientis (Zap), Chenopodium ambrosioides near ambrosioides extract extract), fatty acid monoesters with glycerol or propanediol, neem oil, Beauveria bassiana strains, Metarhizium anisopliae strain F52, Paecilomyces fumosoroseus apopka strain 97, diatomaceous earth (diatomite), dicyclanil (diclanil), dinobuton, dinocap(dinocap), hydrogen cyanide, methyl iodide, karanjin, mercury chloride, methyl isothiocyanate, pentachlorophenol, phosphine, piperonyl butoxide, polynactins, sabadilla, sulcofuron-sodium, tribufos, aldrin Aldrin, amidithione, amidothioate, aminocarb, amiton, aramite, athidathion, azothoate, barium polysulfide, benclothiaz, 5-(1,3-benzodioxol-5-yl)-3-hexylcyclohex-2-enone (5-(1,3-benzodioxole-5-yl)-3-hexylcyclohexa-2-enone), 1,1-bis(4-chlorophenyl)-2-ethoxyethanol, butonate, butopyronoxyl, 2-(2-butoxyethoxy)ethyl thiocyanate, camphechlor, chlorbenside, chlordecone, chlordimeform (chlordimeform), chlorphenetole, chlorfenson, fluazuron, metaldehyde, bialaphos, levamisole hydrochlorideLevamisol, amidoflumet, pyrafluprole, pyriprole, tralopyril, flupyrazofos, diofenolan, chlorbenzilate, flufenzine, benzomate, flufenerim, albendazole, oxibendazole, fenbendazole, metam sodium (metam-sodium), 1,3-dichloropropene, ethylene dibromide, acrylonitrile, bis(2-chloroethyl)ether, 1-bromo-2-chloroethane, 3-bromo-1-chloroprop-1-ene, bromocyclen, carbon disulfide, carbon tetrachloride, nemadectin Nemadecin, cymiazole, cytokinin, 2-(octylthio)ethanol, potassium oleate, sodium oleate, machine oil, tar oil, anabasine, morantel tartrate, pyrethrum, rapeseed oil, soybean lecithin, starch, hydroxypropyl starch (hydroxypropyl starch), fatty acid glyceridesDecanoyl octanoylglycerol, diatomaceous earth (diatomite), tripropyl isocyanurate (TPIC), 1,3-dichloropropene (DD), peroxocarbonate, verbin (MB-599), bis(2,3,3,3-tetrachloropropyl) ether, bis(2-chloro-1-methylethyl) ether (DCIP), ENT-8184 (N-(2-Ethylhexyl)bicyclohept-5-ene-2,3-dicarboximide), Bayer 22408 (O,O-diethyl O-naphthalimido phosphorothioate), Bayer 32394 (tris(1-dodecyl-3-methyl-2-phenylbenzimidazolium)hexacyanoferrate), dichloromezotiaz, fluazaindolizine, cyhalodiamide, thioxazaphen (tioxazafen), fluhexafon, fluralaner, tetrachlorantraniliprole, sarolaner, lotilaner, tigolaner, cycloxaprid, fluensulfone, benzpyrimoxan, cyclopyrazoflor, oxazosulfyl, dipropylpyridaz, ciproflanilide (cyproflanilide), nicofluprole, cyclobutrifluram, cycloxylidin, paichongding, guadipyr(guadipyr), cyetopyrafen, flupentiofenox, pyriminostrobin, chloroprallethrin, kappa-bifenthrin, kappa-tefluthrin, heptafluthrin (heptafluthrin), spirobudifen, thiolantraniliprole, trifluenfuronate, indazapyroxamet, phenmezoditiaz, fluchlordiniliprole, spidoxamat

[0072] The plant disease control composition of the present invention will be described in detail with reference to Examples and Test Examples, but the present invention is not limited to these Examples and Test Examples.

[0073] The oil components and surfactants used in the Examples and Test Examples are shown in Tables 1 and 2. However, the present invention is not limited to these in any way.

[0074]

[0075]

[0076]

[0077]

[0078]

[0079] In the following examples and test examples, "parts" refers to "parts by mass".

[0080] Example 1 D-tagatose (40 parts), soybean oil (52.5 parts) as an oil component, and Sorpol 4320 (7.5 parts) as a surfactant were mixed in a mortar until uniform, to obtain a plant disease control composition. The test results of Example 1 are shown in Table 3.

[0081] [Examples 2 to 23] D-tagatose, oil components, and surfactants were used in the compositions shown in Table 3, and plant disease control pesticide compositions were obtained in the same manner as in Example 1. The test results of Examples 2 to 23 are shown in Table 3.

[0082] Example 24 D-tagatose (40.6 parts), soybean oil (51.86 parts) as an oil component, and Emal 10PT (0.13 parts) and Sorpol CA-15 (7.41 parts) as surfactants were mixed in a mortar until uniform, to obtain a plant disease control composition. The test results of Example 24 are shown in Table 4.

[0083] [Examples 25 to 43] D-tagatose, oil components and surfactants were used in the compositions shown in Table 4, and plant disease control compositions were obtained in the same manner as in Example 24. The test results of Examples 25 to 43 are shown in Table 4.

[0084] Example 44 D-tagatose (40.6 parts), soybean oil (51.9 parts) as an oil component, and Newcalgen 110 (7.5 parts) as a surfactant were mixed in a mortar until uniform, to obtain a plant disease control composition. The test results of Example 44 are shown in Table 5.

[0085] [Examples 45 to 64] D-tagatose, oil components, and surfactants were used in the compositions shown in Table 5, and plant disease control compositions were obtained in the same manner as in Example 44. The test results of Examples 45 to 64 are shown in Table 5.

[0086] Example 65 D-tagatose (40.6 parts), soybean oil (53.57 parts) as an oil component, and Newkalgen 110 (5.0 parts) and Newkalgen EP-60P (0.83 parts) as surfactants were mixed in a mortar until uniform, to obtain a plant disease control composition. The test results of Example 65 are shown in Table 6.

[0087] [Examples 66 to 162] D-tagatose, oil components, and surfactants were used in the compositions shown in Table 6, and plant disease control compositions were obtained in the same manner as in Example 65. The test results of Examples 66 to 162 are shown in Table 6.

[0088] Example 163 D-tagatose (40.0 parts), liquid paraffin (52.5 parts) as an oil component, and Sorpol 4273 (7.5 parts) as a surfactant were mixed in a mortar until uniform, to obtain a plant disease control composition. The test results of Example 163 are shown in Table 7.

[0089] [Examples 164 to 232] Plant disease control pesticide compositions were obtained in the same manner as in Example 163, using D-tagatose, oil components, and surfactants in the compositions shown in Table 7. The test results of Examples 164 to 232 are shown in Table 7.

[0090] Example 233 D-tagatose (40.6 parts) and liquid paraffin (59.4 parts) as an oil component were mixed in a mortar until uniform, to obtain a plant disease control composition. The test results of Example 233 are shown in Table 8.

[0091] [Examples 234 to 328] Plant disease control compositions were obtained in the same manner as in Example 233, using D-tagatose, oil components, and surfactants in the compositions shown in Table 8. The test results of Examples 234 to 328 are shown in Table 8.

[0092] In these test examples, control tests were carried out against cucumber powdery mildew (CPM), grape downy mildew (VDM), grape powdery mildew (VPM), tomato gray mold (TGM), tomato late blight (LB), apple scab (AS), and soybean rust (SbR). Details of the test methods are shown below.

[0093] (Cucumber Powdery Mildew: CPM / Cucumber Powder Mildew) Test plants (cucumber variety: Sagami Hanshiro Setsunari) were sown and then cultivated until one true leaf emerged. In the test, each formulation was diluted with water to a predetermined concentration (2.5 ml / pot) and sprayed. One day after spraying, 1.0 x 10 ５ A conidia suspension of cucumber powdery mildew ( Podosphaera xanthii ) was sprayed onto the plants at a concentration of 1 / ml, and the degree of disease development was examined 7 days later to evaluate the efficacy.

[0094] (Grape downy mildew: VDM / Vine Downy Mildew) Test plants (grape variety: Neo Muscat) were sown and then grown until 3-4 true leaves had developed. In the test, each formulation was diluted with water to a predetermined concentration (2.5 ml / pot) and sprayed. One day after spraying, 1.0 x 10 ４　 The plants were inoculated by spraying with a zoosporangium suspension of Plasmopara viticola at a concentration of 1 / ml, and then left in an inoculation room at 20°C for 24 hours to promote the onset of disease. The disease severity was examined 10 days after inoculation to evaluate the efficacy.

[0095] (Grape powdery mildew: VPM / Vine Powdery Mildew) Test plants (grape variety: Neo Muscat) were sown and then cultivated until 3-4 true leaves had developed. In the test, each formulation was diluted with water to a predetermined concentration and sprayed with a diluted solution (2.5 ml / pot). One day after spraying, 1.0 x 10 ５ The plants were inoculated by spraying with a conidial suspension of grape powdery mildew (Uncinula necator) at a concentration of 1 / ml, and then left in an inoculation room at a room temperature of 20°C for 24 hours to promote the onset of disease. The disease severity was examined 10 days after inoculation to evaluate the efficacy.

[0096] (Tomato Gray Mold: TGM / Tomato Gray Mold) Test plants (tomato variety: Large Fukuju) were sown and then cultivated until three true leaves had developed. In the test, each formulation was diluted with water to a predetermined concentration (2.5 ml / pot) and sprayed. One day after spraying, 1.0 x 10 ５ The plants were inoculated by spraying with conidia of Botrytis cinerea at a concentration of 1 / ml, and then left in an inoculation room at 23°C for 48 hours to promote disease development. Two days after inoculation, the disease severity was examined to evaluate the efficacy.

[0097] (Tomato late blight: LB / Late Bright) Test plants (tomato variety: Large Fukuju) were sown and then grown until three true leaves had developed. In the test, each formulation was diluted with water to a predetermined concentration (2.5 ml / pot) and sprayed. One day after spraying, 1.0 x 10 ３The plants were inoculated by spraying with a suspension of zoosporangia of Phytophthora infestans at a concentration of 1 / ml, and then left in an inoculation room at 20°C for 24 hours to promote the onset of disease. Seven days after inoculation, the severity of the disease was examined to evaluate its efficacy.

[0098] (Apple scab: AS / Apple Scab) After sowing, test plants (apple variety: Orin) were grown until 4-5 true leaves had developed. In the test, each formulation was diluted with well water to the specified concentration (2.5 ml / pot) and sprayed. One day after spraying, 1.0 x 10 ５ The plants were inoculated by spraying with a conidia suspension of Venturia inaequalis at a concentration of 1000 / ml, and then left in an inoculation room at a room temperature of 20°C for 24 hours to promote the onset of disease. The severity of disease was examined 10 days after inoculation to evaluate the efficacy.

[0099] (Soybean rust: SbR / Soybean Rust) After sowing, test plants (soybean variety: Enrei) were grown until two true leaves emerged. In the test, each formulation was diluted with well water to the specified concentration and sprayed with a diluted solution (2.5 ml / pot). One day after spraying, 1.0 x 10 ５ The soybean plants were inoculated by spraying with a suspension of uredospores of soybean rust fungus (Phakopsora pachyrhizi) at a concentration of 1 / ml, and then left in an inoculation room at 20°C for 24 hours to promote the onset of disease. The severity of disease was examined 7 days after inoculation to evaluate the efficacy.

[0100] The disease control tests evaluated using the above methods were evaluated for the degree of disease using the following indices. The control value was calculated from the degree of disease. [Disease level] 0: No disease 0.1: Disease area is about 3% 0.3: Disease area is about 10% 0.8: Disease area is about 25% 1.5: Disease area is about 50% 2: Disease area is about 70% 3: Disease area is about 95% [Control value] Control value = 100 {1 - (n / N)} N = disease level in the untreated area, n = disease level in each area Note that values ​​for which the test was not conducted are marked as nt, and values ​​for which the test was not successful are marked as -. Compared with D-tagatose wettable powder formulations (Test Examples 1 to 6, formulations containing 80% D-tagatose, 0.25% Newkalgen SX-C, 0.25% Emal 10PT, and 5% Molwet D425 as described in WO2014 / 142074 were used; Test Example 7, formulations containing 24% D-tagatose, 0.25% Newkalgen SX-C, 5% Emal 10PT, and 5% Molwet D425 as described in WO2014 / 142074 were used), the degree of improvement in the control value by the formulation of the present invention was evaluated using the following index (control value index). 0: Control value is lower than that of the D-tagatose wettable powder formulation. 1: Improved efficacy was observed compared to the D-tagatose wettable powder formulation (improvement of 1 or more but less than 10). 2: Greater efficacy was observed compared to the D-tagatose wettable powder formulation (improvement of 10 or more).

[0101] Evaluation method for rain resistance test [Test Examples 1 to 7] Rain resistance tests were conducted against cucumber powdery mildew (CPM), grape downy mildew (VDM), grape powdery mildew (VPM), and tomato late blight (LB). Details of the test method are shown below.

[0102] (Cucumber Powdery Mildew Rain Tolerance Test: CPM RF / Cucumber Powdery Mildew Rain Fastness) Test plants (cucumber variety: Sagami Hanshiro Setsunari) were sown and then cultivated until one true leaf emerged. In the test, each formulation was diluted with water to a predetermined concentration and sprayed with a diluted solution (2.5 ml / pot). One day after spraying, the seedlings were subjected to 20 mm of rain, and then sprayed with 1.0 x 10 ５The plants were inoculated by spraying with a suspension of conidia of Sphaerotheca cucurbitae at a concentration of 1 / ml. After 7 days, the degree of disease development was examined and the efficacy was evaluated.

[0103] (Grape downy mildew: VDM RF / Vine Downy Mildew Rain Fastness) Test plants (grape variety: Neo Muscat) were sown and then grown until 3 to 4 true leaves had developed. In the test, each formulation was diluted with water to a predetermined concentration and sprayed with a diluted solution (2.5 ml / pot). One day after spraying, the seedlings were subjected to 20 mm of rain, and then sprayed with 1.0 x 10 ３ The plants were inoculated by spraying with a suspension of zoosporangia of grape downy mildew (Plasmodpara viticola) at a concentration of 1 / ml, and then left in an inoculation room at 20°C for 24 hours to promote disease development. Ten days after inoculation, the disease severity was examined to evaluate the efficacy.

[0104] (Grape powdery mildew: VPM RF / Vine Powdery Mildew Rain Fastness) Test plants (grape variety: Neo Muscat) were sown and then grown until 3-4 true leaves had developed. In the test, each formulation was diluted with water to a predetermined concentration and sprayed with a diluted solution (2.5 ml / pot). One day after spraying, the seedlings were subjected to 20 mm of rain, and then sprayed with 1.0 x 10 ５ The plants were inoculated by spraying with a suspension of zoosporangia of Uncinula necator at a concentration of 1 / ml. The disease severity was examined 10 days after inoculation to evaluate the efficacy.

[0105] (Tomato late blight: LB RF / Late Bright Rain Fastness) Test plants (tomato variety: Large Fukuju) were sown and then cultivated until three true leaves had developed. In the test, each formulation was diluted with water to a predetermined concentration (2.5 ml / pot) and sprayed. One day after spraying, 1.0 x 10 ３ The plants were inoculated by spraying with a suspension of zoosporangia of Phytophthora infestans at a concentration of 1 / ml, and then left in an inoculation room at 20°C for 24 hours to promote the onset of disease. Seven days after inoculation, the severity of the disease was examined to evaluate its efficacy.

[0106] The rain resistance of plant disease control agents containing D-tagatose, an oil component, and a surfactant against cucumber powdery mildew, grape downy mildew, and grape powdery mildew was evaluated using the following index: Compared to D-tagatose wettable powder formulations (Test Examples 1 to 6, formulations containing 80% D-tagatose, 0.25% Newkalgen SX-C, 0.25% Emal 10PT, and 5% Molwet D425 as described in WO2014 / 142074 were used; Test Example 7, formulations containing 24% D-tagatose, 0.25% Newkalgen SX-C, 5% Emal 10PT, and 5% Molwet D425 as described in WO2014 / 142074 were used), the degree of improvement in rain resistance of the formulations of the present invention was evaluated using the following index (control value index). 0: Rain resistance at the same level as the D-tagatose wettable powder formulation 1: Improved rain resistance compared to the D-tagatose wettable powder formulation (control value of 1 or more)

[0107] Test Example 1: Evaluation of plant disease control agents containing D-tagatose, an oil component, and multiple surfactants. The efficacy and rain resistance of plant disease control agents containing D-tagatose, an oil component (soybean oil or liquid paraffin), and multiple surfactants (nonionic surfactant, anionic surfactant) prepared in the Examples were evaluated against diseases such as cucumber powdery mildew. The degree of improvement in control value and the degree of improvement in rain resistance compared to the D-tagatose wettable powder formulation were used as indicators for evaluation, as described in the evaluation methods for plant disease control tests and rain resistance tests. The results are shown in Table 3.

[0108]

[0109] A plant disease control agent containing D-tagatose, an oil component (soybean oil or liquid paraffin), and multiple surfactants (nonionic surfactants, anionic surfactants) showed significantly improved efficacy and rain resistance against cucumber powdery mildew, grape downy mildew, tomato gray mold, grape powdery mildew, tomato late blight, apple scab, and soybean rust, compared to a D-tagatose wettable powder formulation.

[0110] Test Example 2: Evaluation of plant disease control agents containing D-tagatose, soybean oil, and a nonionic surfactant The plant disease control agents containing D-tagatose, soybean oil, and a nonionic surfactant prepared in the Examples were evaluated for efficacy against diseases such as cucumber powdery mildew and for rain resistance. As in Test Example 1, the evaluation was conducted using the degree of improvement in control value and the degree of improvement in rain resistance as indicators. The results are shown in Table 4.

[0111]

[0112] A plant disease control agent containing D-tagatose, soybean oil, and a nonionic surfactant showed significantly improved efficacy and rain resistance against cucumber powdery mildew, grape downy mildew, tomato gray mold, grape powdery mildew, tomato late blight, apple scab, and soybean rust, compared with a D-tagatose wettable powder formulation.

[0113] Test Example 3 Evaluation of Plant Disease Control Agents Containing D-Tagatose, Soybean Oil, and Surfactants (Nonionic Surfactant, Anionic Surfactant) The plant disease control agents containing D-tagatose, soybean oil, and surfactants (nonionic surfactant, anionic surfactant) prepared in the Examples were evaluated for efficacy against diseases such as cucumber powdery mildew and rain resistance. As in Test Example 1, the degree of improvement in control value and the degree of improvement in rain resistance were used as indicators for evaluation. The results are shown in Table 5.

[0114]

[0115] A plant disease control agent containing D-tagatose, soybean oil, and surfactants (nonionic surfactants and anionic surfactants) showed significantly improved efficacy and rain resistance against cucumber powdery mildew, grape downy mildew, tomato gray mold, grape powdery mildew, tomato late blight, apple scab, and soybean rust, compared to a D-tagatose wettable powder formulation.

[0116] Test Example 4 Evaluation of Plant Disease Control Agents Containing D-Tagatose, Soybean Oil, and Various Surfactants The plant disease control agents containing D-tagatose, soybean oil, and various surfactants prepared in the Examples were evaluated for efficacy against diseases such as cucumber powdery mildew and for rain resistance. As in Test Example 1, the evaluation was conducted using the degree of improvement in control value and the degree of improvement in rain resistance as indicators. The results are shown in Table 6.

[0117]

[0118] A plant disease control agent containing D-tagatose, soybean oil, and various surfactants showed significantly improved efficacy and rain resistance against cucumber powdery mildew, grape downy mildew, tomato gray mold, grape powdery mildew, tomato late blight, apple scab, and soybean rust, compared to a D-tagatose wettable powder formulation.

[0119] Test Example 5 Evaluation of Plant Disease Control Agents Containing D-Tagatose, Liquid Paraffin, and Surfactants (Nonionic Surfactant, Anionic Surfactant) The plant disease control agents containing D-tagatose, liquid paraffin, and surfactants (nonionic surfactant, anionic surfactant) prepared in the Examples were evaluated for efficacy against diseases such as cucumber powdery mildew and rain resistance. As in Test Example 1, the degree of improvement in control value and the degree of improvement in rain resistance were used as indicators for evaluation. The results are shown in Table 7.

[0120]

[0121] A plant disease control agent containing D-tagatose, liquid paraffin, and surfactants (nonionic surfactants and anionic surfactants) showed significantly improved efficacy and rain resistance against cucumber powdery mildew, grape downy mildew, tomato gray mold, grape powdery mildew, tomato late blight, apple scab, and soybean rust, compared to a D-tagatose wettable powder formulation.

[0122] Test Example 6 Evaluation of Plant Disease Control Agents Containing D-Tagatose, Various Oil Components, and Surfactants (Nonionic Surfactant, Anionic Surfactant) The plant disease control agents containing D-tagatose, various oil components, and surfactants (nonionic surfactant, anionic surfactant) prepared in the Examples were evaluated for efficacy against diseases such as cucumber powdery mildew and rain resistance. As in Test Example 1, the degree of improvement in control value and the degree of improvement in rain resistance were used as indicators for evaluation. The results are shown in Table 8.

[0123]

[0124] A plant disease control agent containing D-tagatose, various oil components, and surfactants (nonionic surfactants and anionic surfactants) showed significantly improved efficacy and rain resistance against cucumber powdery mildew, grape downy mildew, tomato gray mold, grape powdery mildew, tomato late blight, apple scab, and soybean rust, compared to a D-tagatose wettable powder formulation.

[0125] Test Example 7 Evaluation of a plant disease control agent obtained by field application of a D-tagatose wettable powder formulation with a commercially available wetting agent containing an oil component and a surfactant The efficacy and rain resistance of a plant disease control agent obtained by field application of a D-tagatose wettable powder formulation with a commercially available wetting agent containing an oil component and a surfactant against diseases such as cucumber powdery mildew were evaluated. As in Test Example 1, the degree of improvement in control value and the degree of improvement in rain resistance were used as indicators for evaluation. The results are shown in Table 9.

[0126]

[0127] As a result of rain resistance tests using cucumber powdery mildew, grape downy mildew, grape powdery mildew, and tomato late blight as indicators, when a D-tagatose wettable powder formulation was mixed with a commercially available wetting agent containing an oil component and a surfactant in a ratio of 1:1 or 1:0.5, a significant improvement in rain resistance was observed when the formulation was mixed with a wetting agent containing esterified or methyl-esterified vegetable oil or a wetting agent containing liquid paraffin.

[0128] The present invention provides a plant disease control composition containing an oil component and a surfactant, which composition enhances the plant disease control effect of D-tagatose, a method for controlling plant diseases using the plant disease control composition, and a method for enhancing the plant disease control effect and / or rain tolerance of D-tagatose. The plant disease control composition can be used as a foliage spray, soil treatment agent, or seed treatment agent, and is capable of controlling various plant diseases without causing phytotoxicity to the host plant.

Claims

1. A plant disease control composition comprising D-tagatose, at least one selected from oil components, and at least one selected from surfactants.

2. The plant disease control composition according to Claim 1, wherein the oil component is at least one selected from the group consisting of fats and oils, mineral oils, and essential oils.

3. The plant disease control composition according to Claim 2, wherein the fat and oil is a vegetable oil.

4. The plant disease control composition according to Claim 2, wherein the mineral oil is liquid paraffin.

5. The plant disease control composition according to Claim 2, wherein the essential oil is at least one selected from the group consisting of orange oil, bergamot oil, and lavender oil.

6. The plant disease control composition according to Claim 3, wherein the vegetable oil is at least one selected from the group consisting of soybean oil, rapeseed oil, castor oil, linseed oil, macadamia nut oil, sunflower oil, olive oil, coconut oil, and methylated seed oil derived from vegetable oils.

7. The plant disease control composition according to any one of Claims 1 to 6, wherein the surfactant is at least one selected from the group consisting of nonionic surfactants and anionic surfactants.

8. The plant disease control composition according to Claim 7, wherein the nonionic surfactant is at least one selected from the group consisting of polyoxyalkylene alkyl ether, polyoxyalkylene sorbitol fatty acid ester, sorbitan fatty acid ester, glycerin fatty acid ester, sucrose fatty acid ester, and polyoxyethylene sorbitan fatty acid ester.

9. The plant disease control composition according to Claim 7, wherein the anionic surfactant is at least one selected from the group consisting of lignin sulfonate, formalin condensate of aryl sulfonate, polycarboxylate, α-olefin sulfonate, alkyl sulfate, sulfosuccinate, and aryl sulfonate.

10. The plant disease control composition according to any one of Claims 1 to 6, which is a plant disease control agent against fungal diseases and bacterial diseases.

11. A plant disease control method, characterized by applying the plant disease control composition according to any one of Claims 1 to 6 to a plant.

12. The method for controlling plant diseases according to claim 11, wherein the application to the plant is by bringing the plant disease control composition into contact with the plant body, or by bringing it into contact with the roots or rhizomes of the plant by including it in the cultivation soil or hydroponic culture solution.

13. The application to the cultivation soil or hydroponic culture solution is, in the case of soil, treatment of the soil surface with the plant disease control composition, irrigation of the soil, or mixing into the soil, and in the case of the hydroponic culture solution, diluting the plant disease control composition in the hydroponic culture solution, the method for controlling plant diseases according to claim 11.