Ternary insecticidal composition comprising spiromesifen, flubendiamide and emamectin benzoate

Abstract

The present invention relates to stable synergistic insecticidal composition for the control of plant and crop pests including insect pests.

Description

[0001] TERNARY INSECTICIDAL COMPOSITION COMPRISING SPIROMESIFEN, FLUBENDIAMIDE AND EMAMECTIN BENZOATE

[0002] FIELD OF THE INVENTION

[0003] The present invention relates to stable synergistic insecticidal composition for the control of plant and crop pests including insect pests. More particularly, the present invention relates to a stable synergistic insecticidal composition comprising A) Compound of Formula I, chemically known as 3-mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3, 3 -dimethylbutyr ate or its agrochemically acceptable salts, esters and derivatives; B) Emamectin or its agrochemically acceptable salts, esters and derivatives; and C) Compound of Formula II, chemically known as 3-iodo-A'-(2-mesyl- l , l - dimethylethyl)-A-{4-[ 1 ,2,2,2-tetrafluoro- 1 (trifhroromethyl)ethyl]-o-tolyl}phthalamide or its agrochemically acceptable salts, esters and derivatives.The present invention also relates to a process for preparation of such stable synergistic insecticidal composition for synergistic and efficacious control of insect pests.

[0004] BACKGROUND OF THE INVENTION

[0005] Background description includes information that may be useful in understanding the present invention. It is not an admission that any of the information provided herein is prior art or relevant to the present invention, or that any publication specifically or implicitly referenced is prior art.

[0006] Crop protection is critical from early stages of crop development. Preventing pests and diseases at the root of the crop during root development leads to increased crop health and yield. The vulnerability of crops to pests makes pest control one of the major management components of the total crop production system. Insects are very destructive to crop plants and can significantly reduce crop yields and quality. Insecticides help minimize this damage by controlling insect pests.

[0007] Insecticides are used widely and very frequently in commercial agriculture and have enabled an enormous increase in crop yields and product quality which ultimately increased the ease to farmers in term of economic advantage as well as ease of farming activities. Practical agricultural experience has shown that the repeated and exclusive application of an individual active compound in the control of insect pests leads in many cases to a selection of those pests which have developed natural or adapted resistance against the active compound in question. Effective control of these pests with the active compound in question is then no longer possible.

[0008] It is always preferable to be able to reduce the amount of chemical agents released into the environment while still ensuring effective pest control. Although pest control agent combinations have been studied, a high synergistic action has not always been found. There is however a need for improvement of these combinations. Single active compositions used over a long period of time has resulted in resistance. With the onset of resistance to certain pests, there is a need in the art for a combination of actives that decrease the chances of resistance and improves the spectrum of disease and insect pest control.

[0009] In order to reduce the risk of insect pests becoming resistant to certain active compounds, mixtures of different active compounds are nowadays conventionally employed for controlling insect pests. By combining active compounds having different mechanisms of action, it is possible to ensure successful control over a relatively long period of time.

[0010] There also exists the need for insect pest control agents that combine knock-down activity with prolonged control, that is, fast action with long lasting action.

[0011] It is therefore an object of the present invention to provide insecticidal composition which (i) reduces dosage rate, (ii) enhances the spectrum of activity or combining knock-down activity with prolonged control or (iii) provides resistance management or (iv) is stable for longer period and has extended, improved shelf life.

[0012] Insecticidal compositions that can be applied at as low a dose as possible and be effective in controlling pest species of insects while causing as little harm as possible to beneficial insects and minimal disturbance in the environment are in demand by the farming community. Insects are very destructive to crops and can result in significant loss of crop yield and quality, which results in economic loss to the grower and increased cost to the consumer. Combinations of insecticides are typically used to broaden the spectrum of insect control, to minimize the doses of chemicals used, to retard resistance development and to reduce the cost of treatment through additive effect. Although, many combinations of insecticidal agents have been studied, a synergistic effect is rarely attained. Therefore, there is still a need for novel insecticidal composition comprising combination of insecticides which have different chemistry but are broad spectrum to cover efficacious control of large number of insect pests, which also exhibits synergistically enhanced action, a broader scope of activity at a reduced cost of treatment.

[0013] It is an object of the present invention to provide, mixtures and compositions which, when applied at a reduced total amount of active compounds, have improved activity against the harmful pests and a broadened activity spectrum. It is a further object of the present invention to provide, mixtures and compositions which provide effective resistance management and insect pests control, at application rates which are as low as possible.

[0014] There is a need for an insecticidal formulation that is highly efficient, non- toxic, covers a broader spectrum of insects and is environment friendly and economical. Accordingly, there exists a continuous need for new insecticidal combinations to be applied so as to provide an economical and effective solution in terms of insect control, yield, plant growth, broader crop protection spectrum, reduce the burden on the environment / farmers, healthy foliage, saves labour cost and is yet cost-effective to the end user.

[0015] Further, in general use, the insecticide actives are used in the form of a dilute aqueous composition because it can attain a good interaction with the target organism, such as plants and insects. However, most active insecticide compounds that are used as insecticides are only sparingly or even insoluble in water. The low solubility of such compounds present the challenges and difficulties to formulator in formulating insecticide compounds in stable formulations that can be easily stored for a long time and which still have a high stability and effective activity until end use. This problem especially occurs and may get worsen if more than one active compound is present in the composition. For the reasons mentioned above there is a need to provide further composition of three insecticides as actives having synergistic insect pest control properties. This object is achieved according to the invention by providing the present stable synergistic insecticidal composition.

[0016] There are various prior arts which disclose compositions comprising combination of insecticide actives with diamide insecticide with other insecticides. Some of such prior arts are listed below:

[0017] CN101601394 discloses synergistic insecticidal composition of Flubendiamide and Emamectin benzoate. The weight percentages of raw materials for preparation of the product are respectively: 3-20% of Flubendiamide, 1-10% of emamectin benzoate, and 70-96% of additives.

[0018] IN202121039285 discloses an oil dispersion agrochemical composition comprising: a. Emamectin benzoate present in amount of 0.1% - 20% w / w; b. an active ingredient selected from class of an insecticide or combination thereof present in amount of 0.1% - 30% w / w; c. Poly alkyleneoxide modified Heptamethyl trisiloxane (modified trisiloxane), a super wetting-spreading-penetrating agent is present in an amount of 1% to 10% w / w; d. carrier selected from pongamia oil or palm oil or jojoba oil or combination thereof or blend with vegetable oil present in an amount of 10% to 80% w / w; and one or more formulation excipients.

[0019] However, the prior art formulations have not been found to be effective for control of wide range of insect pests affecting the crops and plants at the same time. Thus, there is a need for a composition which overcomes some of the existing problems and can be prepared easily without much complex manufacturing process.

[0020] Insecticidal compounds of the present invention have an excellent environmental profile, are essentially non-toxic to mammals and other vertebrates, and have exhibited low toxicity towards most non-target invertebrates, including beneficial insects.

[0021] In light of the above, there is still a need for novel insecticidal composition that exhibit synergistically enhanced action, a broader scope of activity and reduced cost of treatment. So, there is a need for a composition comprising A) Compound of Formula I, chemically known as 3- mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3, 3 -dimethylbutyrate or its agrochemically acceptable salts, esters and derivatives; B) Emamectin or its agrochemically acceptable salts, esters and derivatives; and C) Compound of Formula II, chemically known as 3-iodo-A'-(2-mesyl-l,l- dimethylethyl)-A-{4-[l,2,2,2-tetrafhroro-l(trifhioromethyl)ethyl]-c>-tolyl}phthalamide or its agrochemically acceptable salts, esters and derivatives, which overcomes some of the existing problems and can be prepared easily without much complex manufacturing process.

[0022] Accordingly, the present invention provides a stable synergistic insecticidal composition comprising components (compounds) having different basic structures and different functions with well-suited to each other, and a method for controlling plant insect pests. Therefore, the present invention provides a stable synergistic insecticidal composition comprising A) Compound of Formula I, chemically known as 3-mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3,3- dimethylbutyrate or its agrochemically acceptable salts, esters and derivatives; B) Emamectin or its agrochemically acceptable salts, esters and derivatives; and C) Compound of Formula II, chemically known as 3-iodo-A'-(2-mesyl-l,l-dimethylethyl)-A-{4-[l,2,2,2-tetrafluoro- l(trifluoromethyl)ethyl]-c>-tolyl}phthalamide or its agrochemically acceptable salts, esters and derivatives.

[0023] Compound of Formula I, chemically known as 3-mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3,3- dimethylbutyrate, is an insecticidal / acaricidal compound derived from spirocyclic tetronic acids that acts effectively against whiteflies and mites via inhibition of acetyl CoA-carboxylase, a lipid metabolism enzyme. It is board spectrum insecticide for the effective control of Red spider mite, White fly & mite, European Red Mite, Chilli yellow mite for Brinjal, Cotton, Apple, Chilli, Tea, Okra (Bhindi), Tomato. Chemical structure of Compound of Formula I is provided below: Compound of Formula I

[0024] Emamectin is avermectin insecticide. The mode of action of Emamectin is that it has non- systemic action by causing insect paralysis by suppressing muscle contraction. Emamectin is effective against many insect pests particularly Caterpillars, mites, micers, thrips. Chemical structure of Emamectin is Emamectin is used in its ester, salt or derivative forms. Commonly used form of Emamectin is Emamectin Benzoate.

[0025] Emamectin benzoate is the 4'-deoxy-4'-epi-methyl-amino benzoate salt of avermectin Bl (abamectin). Emamectin benzoate is a broad- spectrum insecticide for vegetables and has a very low application rate. The mechanism of action involves stimulation of high-affinity GABA receptors and a consequent increase in membrane chloride ion permeability. Emamectin benzoate with the chemical name of 4 '-methylamino-4' -deoxyabamectin B 1 benzoate is a high- efficiency semisynthetic antibiotic type insecticidal and acaricidal pesticide and the action mechanism of the emamectin benzoate is to interfere the nerve physiological activity of insects, stimulate and release gamma-aminobutyric acid and inhibit the conduction of nerve impulse of the insects. It is more effective when ingested, but it also somewhat effective on contact. When sprayed to foliage, emamectin benzoate penetrates the leaf tissue and forms reservoir within treated leaves, which provides residual activity against pests that ingest the substance when feeding. It is board spectrum insecticide for the effective control of Boll worms, Fruit & shoot borer, Diamond back moth, Thrips, mites, Pod borer, Tea lopper, Leaf folder & Hispa, Green Semi looper, Girdle beetle & Tobacco caterpillar, Yellow stem borer, (scirpophaga incertulus), Diamond back moth ( Plutella xylostella), Fruit borer ( Spodotera litura & Helicoverpa armigera) , Thrips (Scritothripsn dorsalis) , Mites ( Polypagotarsone muslatus), Whiteflies, Jassids, Aphids and Pink Boll Worm, Yellow Mites, Fall Army worm for Cotton, Okra( Bhindi) , Cabbage, Chilli, Brinjal, Red Gram( Arhar / Tur), Chickpea, Grapes, Tea, Paddy, Soybean, Rice, Cauliflower, Maize. Emamectin benzoate has the structure provided below:

[0026]

[0027] Compound of Formula II, chemically known as 3dodo-A'-(2-mesyl-l,l-dimethylethyl)-A-{4- [l,2,2,2-tetrafhioro-l(trifhroromethyl)ethyl]-c>-tolyl} phthalamide is an organofluorine insecticide. It has a role as a ryanodine receptor modulator. The mode of action of Compound of

[0028] Formula II is that it exhibits larvicidal activity as an orally ingested toxicant by targeting and disrupting the Ca2+ balance. This results in rapid cessation of feeding and extended residual control. It is board spectrum insecticide for the effective control of Stem borer, Leaf folder , American boll worm, Pod borer, Diamond back moth, Fruit borer, Maruca spp., Early shoot borer, Spotted Bollworm, Shoot borer, Pod Borer (Spodoptera spp., Defoliators ( Helicoverpa armigera,

[0029] Spodoptera litura and Semilooper), Yellow stem borer, Brown Plant hopper, Cucumber beetle, Fruit fly, Leaf eating caterpillar, Thrips for Rice, Cotton, Pigeon pea (Tur / Arhar), Cabbage, Tomato, Tea, Chilli, Soybean, Groundnut, Black gram, Bengal gram, Sugarcane, Okra. Chemical structure of Compound of Formula II is provided below:

[0030] Compound of Formula II

[0031] The present invention further provides a novel method of preparing composition comprising above mentioned active ingredients, which composition is stable as well as provide desired bio-efficacy, synergy. Embodiments of the present invention may therefore ameliorate one or more of the above- mentioned problems.

[0032] OBJECTS AND ADVANTAGES OF THE INVENTION

[0033] Accordingly, the main object of the present invention is to provide a stable synergistic insecticidal composition for insect pest control affecting crops and plants.

[0034] Another object of the present invention is to provide a stable synergistic insecticidal composition comprising A) Compound of Formula I, chemically known as 3-mesityl-2-oxo-l- oxaspiro[4.4]non-3-en-4-yl 3, 3 -dimethylbutyrate or its agrochemically acceptable salts, esters and derivatives; B) Emamectin or its agrochemically acceptable salts, esters and derivatives; and C) Compound of Formula II, chemically known as 3-iodo-V'-(2-mesyl-l,l-dimethylethyl)-V-{4- [l,2,2,2-tetrafluoro-l(trifluoromethyl)ethyl]-c>-tolyl}phthalamide or its agrochemically acceptable salts, esters and derivatives.

[0035] It is another object of the present invention to provide improved, stable and ready to use stable synergistic insecticidal composition having synergistic and superior properties compared to prior art formulations or mixtures or compositions.

[0036] Another object of the present invention is to provide a process for the preparation of a stable synergistic insecticidal composition comprising A) Compound of Formula I, chemically known as 3-mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3, 3 -dimethylbutyr ate or its agrochemically acceptable salts, esters and derivatives; B) Emamectin or its agrochemically acceptable salts, esters and derivatives; and C) Compound of Formula II, chemically known as 3-iodo-A'-(2-mesyl-l,l- dimethylethyl)-A-{4-[l,2,2,2-tetrafhroro-l(trifluoromethyl)ethyl]-c>-tolyl}phthalamide or its agrochemically acceptable salts, esters and derivatives. The present invention also relates to a process for preparation of such stable synergistic insecticidal composition for control of insect pests.

[0037] Further object of the present invention is to provide a stable synergistic insecticidal composition that provides effective immediate and long-term pest control.

[0038] A further object of the present invention is to provide a method for pest control that is both effective in the short and long term.

[0039] It is another object of the present invention to provide a stable synergistic insecticidal composition which can be easily formulated.

[0040] Yet another object of the present invention is to provide a stable synergistic insecticidal composition that promotes plant health and increases plant yield in the field.

[0041] It is another object of the present invention to provide a novel and effective stable synergistic insecticidal composition which is environmentally safe, possesses broad spectrum bio-efficacy, is non-phytotoxic. It is another object of the present invention to provide a novel and effective stable synergistic insecticidal composition, which improves plant health and provides increased crop yield.

[0042] It is yet another object of the present invention to provide a novel and effective stable synergistic insecticidal composition, which has improved stability during the desired shelf life.

[0043] It is another object of the present invention to provide a novel and effective stable synergistic insecticidal composition, which is economically more beneficial.

[0044] Yet another object of the present invention is to provide a method of synergistic and efficacious control of broad spectrum of insect pests by using a stable synergistic insecticidal composition comprising A) Compound of Formula I, chemically known as 3-mesityl-2-oxo-l- oxaspiro[4.4]non-3-en-4-yl 3, 3 -dimethylbutyrate or its agrochemically acceptable salts, esters and derivatives; B) Emamectin or its agrochemically acceptable salts, esters and derivatives; and C) Compound of Formula II, chemically known as 3-iodo-A'-(2-mesyl-l,l-dimethylethyl)-A-{4- [l,2,2,2-tetrafhroro-l(trifhroromethyl)ethyl]-c>-tolyl}phthalamide or its agrochemically acceptable salts, esters and derivatives.

[0045] Advantages of the present invention are as provided below: The stable synergistic insecticidal composition of the present invention shows:

[0046] • broad spectrum activity against various insect-pests including but not limited to Red spider mite, White fly & mite, European Red Mite, Chilli yellow mite , Boll worms, Fruit & shoot borer, Diamond back moth, Thrips, mites, Pod borer, Tea lopper, Leaf folder & Hispa, Green Semi looper, Girdle beetle & Tobacco caterpillar, Yellow stem borer, (scirpophaga incertulus), Diamond back moth ( Plutella xylostella), Fruit borer ( Spodotera litura & Helicoverpa armigera) , Thrips (Scritothripsn dorsalis) , Mites ( Polypagotarsone muslatus), Whiteflies, Jassids, Aphids and Pink Boll Worm, Yellow Mites, Fall Armyworm, Stem borer, Leaf folder , American bollworm, Maruca spp., Early shoot borer, Spotted Bollworm, Pod Borer (Spodoptera spp., Defoliators ( Helicoverpa armigera, Spodoptera litura and Semilooper), Yellow stem borer, Brown Plant hopper, Cucumber beetle, Fruit fly, Leaf eating caterpillar, Rice Gall midge, Whorl maggot , White backed plant hopper, Brown plant hopper, Sanjose scale , Wooly Aphid, Leaf Webber , Coffee Borer, Dried Fruit Beetle, Flat Grain Beetle, Carpet Beetle , Lesser Grain Borer, Khapra Beetle, Saw Toothed Grain Beetle, Rice Moth, Almond Moth, Cigarette Beetle, Pulse Beetle , Long Headed Floor Beetle, Hispa / blue beetle, European red mite, and various Lepidoptera & Coleopteran etc. including insects resistant to chemicals, and shows excellent controlling effects (synergistic controlling effects) which could never be expected from a single component alone.

[0047] • Also, it shows high plant insects controlling effects against existing insects resistant to chemicals, and no chemical damage against plants is observed.

[0048] • The stable synergistic insecticidal composition of present invention is useful for treatment of plants and crops including but not limited to Paddy, sugarcane, cotton, cabbage, cauliflower, tomato, chilli, brinjal, okra (Bhindi), soybean, Tea, Red Gram (Arhar / Tur), Chickpea, Grapes, Maize, Pigeon Pea , Groundnut, Bengal Gram, Black gram, Cucumber, Grains Millet, Pulses Dry Fruits, Nuts Spices & Oil Seeds ,turf and forage, cruciferous, cucurbits, grapevines, pepper, fodder beet, oil seed rape, pansy.

[0049] • The stable synergistic insecticidal composition of the present invention resulted in significantly lower pest population of fruit borer and mite pest in Tomato crop as compared to the binary combination and untreated check.

[0050] • The stable synergistic insecticidal composition of the present invention is significantly superior from its individual product or readily available product in market in reducing the fruit borer and mite population in tomato crop.

[0051] • The stable synergistic insecticidal composition of the present invention provides improved yield as compared to the untreated control and binary and solo treatments.

[0052] • The stable synergistic insecticidal composition of the present invention is having higher Cost: Benefit Ratio.

[0053] • The stable synergistic insecticidal composition of the present invention is economical. • The stable synergistic insecticidal composition of the present invention shows no adverse impact on natural enemies and no phytotoxicity on crops.

[0054] • The stable synergistic insecticidal composition of the present invention is highly effective in controlling insect pests and increasing production of crops yield at lower doses of the products in the combination, thus the invention will be cost effective and safer to the environment.

[0055] SUMMARY OF THE INVENTION:

[0056] The present invention relates to a stable synergistic insecticidal composition comprising A) Compound of Formula I, chemically known as 3-mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3,3- dimethylbutyrate or its agrochemically acceptable salts, esters and derivatives; B) Emamectin or its agrochemically acceptable salts, esters and derivatives; and C) Compound of Formula II, chemically known as 3-iodo- V'-(2-mesyl- 1,1 -dimethylethyl) -2 -{ 4- [ 1,2,2, 2-tetrafluoro- l(trifluoromethyl)ethyl]-c>-tolyl}phthalamide or its agrochemically acceptable salts, esters and derivatives. The present invention also relates to a process for preparation of such stable synergistic insecticidal composition for control of insect pests.

[0057] Insecticidal composition of the present invention is stable, safe to handle, environmentally safe and cost effective. The insecticides used in composition of the present invention act synergistically to cover broader spectrum of insect pests of crops.

[0058] In one embodiment, the present invention provides a stable synergistic insecticidal composition comprising bioactive amounts of:

[0059] A) Compound of Formula I i.e. 3-mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3,3- dimethylbutyrate or its agrochemically acceptable salts, esters and derivatives;

[0060] B) Emamectin or its agrochemically acceptable salts, esters and derivatives; and

[0061] C) Compound of Formula II i.e. 3-iodo- V'-(2-mesyl-l , 1 -dimetbyletbyl )- / V- { 4-[ 1 ,2,2,2-tetrafluoro- l(trifluoromethyl)ethyl]-c>-tolyl}phthalamide or its agrochemically acceptable salts, esters and derivatives. In a preferred embodiment, the present invention provides a stable synergistic insecticidal composition comprising:

[0062] A) Compound of Formula I i.e. 3-mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3,3- dimethylbutyrate or its agrochemically acceptable salts, esters and derivatives, in the range of 0.1 to 85% by weight of the composition;

[0063] B) Emamectin or its agrochemically acceptable salts, esters and derivatives, in the range of 0.1 to 85% by weight of the composition; and

[0064] C) Compound of Formula II i.e.3-iodo-A'-(2-mesyl- 1,1 -dimethylethyl)-A-{4-[ 1,2,2, 2-tetrafluoro- l(trifluoromethyl)ethyl]-c>-tolyl} phthalamide or its agrochemically acceptable salts, esters and derivatives, in the range of 0.1 to 85% by weight of the composition.

[0065] In one another preferred embodiment, the present invention provides a stable synergistic insecticidal composition comprising:

[0066] A) Compound of Formula I i.e. 3-mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3,3- dimethylbutyrate or its agrochemically acceptable salts, esters and derivatives, in the range of 0.1 to 85% by weight of the composition;

[0067] B) Emamectin Benzoate, in the range of 0.1 to 85% by weight of the composition; and

[0068] C) Compound of Formula II i.e.3-iodo-A'-(2-mesyl-l,l-dimethylethyl)-A-{4-[l,2,2,2-tetrafluoro- l(trifluoromethyl)ethyl]-c>-tolyl} phthalamide or its agrochemically acceptable salts, esters and derivatives, in the range of 0.1 to 85% by weight of the composition.

[0069] In a more preferred embodiment, the present invention provides a stable synergistic insecticidal composition comprising:

[0070] A) Compound of Formula I i.e. 3-mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3,3- dimethylbutyrate or its agrochemically acceptable salts, esters and derivatives, in the range of 0.1 to 55% by weight of the composition;

[0071] B) Emamectin Benzoate, in the range of 0.1 to 55% by weight of the composition; and

[0072] C) Compound of Formula II i.e.3-iodo-A'-(2-mesyl-l,l-dimethylethyl)-A-{4-[l,2,2,2-tetrafluoro- l(trifluoromethyl)ethyl]-c>-tolyl} phthalamide or its agrochemically acceptable salts, esters and derivatives, in the range of 0.1 to 55% by weight of the composition. In one another embodiment, the synergistic insecticidal composition of the present invention further comprises one or more agrochemically acceptable excipients.

[0073] In yet another embodiment of the present invention, there is also provided a process for the preparation of synergistic pesticidal composition comprising A) Compound of Formula I i.e. 3- mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3, 3 -dimethylbutyrate or its agrochemically acceptable salts, esters and derivatives;

[0074] B) Emamectin or its agrochemically acceptable salts, esters and derivatives; and

[0075] C) Compound of Formula II i.e. 3-iodo-7V'-(2-mesyl-l , 1 -dimethylethyl)-A-{4-[l ,2,2,2-tetrafluoro- l(trifluoromethyl)ethyl]-c>-tolyl}phthalamide or its agrochemically acceptable salts, esters and derivatives.

[0076] In yet another embodiment of the present invention, the stable synergistic insecticidal composition of the present invention is formulated as but not limited to Capsule suspension (CS), Dispersible concentrate (DC), Dustable powder (DP), Powder for dry seed treatment (DS), Emulsifiable concentrate (EC), Emulsifiable granule (EG), Emulsion water-in-oil (EO), Emulsifiable powder (EP), Emulsion for seed treatment (ES), Emulsion oil-in-water (EW), Flowable concentrate for seed treatment (FS), Granules (GR), Micro -emulsion (ME), Oil-dispersion (OD), Oil miscible flowable concentrate (OF), Oil miscible liquid (OL), Oil dispersible powder (OP), Suspension concentrate (SC), Suspension concentrate for direct application (SD), Suspo-emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Spreading oil (SO), Water soluble powder (SP), Water soluble tablet (ST), Ultra-low volume (ULV) suspension, Tablet (TB), Ultra-low volume (ULV) liquid, Water dispersible granules (WG), Wettable powder (WP), Water dispersible powder for slurry seed treatment (WS), Water dispersible tablet (WT), a mixed composition of CS and SC (ZC), a mixed composition of CS and SE (ZE) or a mixed composition of CS and EW (ZW).

[0077] In another embodiment of the present invention, the stable synergistic insecticidal composition of the present invention further comprises one or more agrochemically acceptable excipients including but not limited to the group comprising surfactant(s) / dispersing agent(s), anti-freezing agent(s), emulsifier(s), anti-foaming agent / defoamer(s), wetting agent(s), antimicrobial / anti- bacterial agent(s), thickening agent / thickener(s), quick coating agent(s) or sticking agents / sticker(s), spreader(s), binder(s), pH-adjusting agent(s), anti-caking agent(s), adjuvant(s), filler(s) / suspension aid(s), colorant(s), carrier(s), buffering agent(s), rheology modifier(s), solvent(s), co-solvent(s) or a combination thereof. Additional components may also be included, e.g., protective colloids, carriers, adhesives, thixotropic agents, penetration agents, stabilisers, sequestering agents. More generally, the active materials can be combined with any solid or liquid carrier / additive, which complies with usual formulation techniques.

[0078] In one embodiment of the present invention, the present insecticidal composition is stable and has enhanced shelf life.

[0079] In an embodiment of the present invention the present stable synergistic insecticidal composition controls various pests in field crops, vegetables, oil seed and pulses, horticulture & forestry, veterinary, etc.

[0080] In yet another embodiment of the present invention, the present stable synergistic insecticidal composition can be applied to crops but not limited to Wheat, Groundnut, Chickpea, Chilli, Rice (Paddy), Onion, Soybean, Black gram, Cumin, Cabbage, Cucumber, Apple, Tomato, Potato Grapes, Black Gram, Okra, Mango, Tea, Coffee, Maize, Banana, Corn, Cotton, Pomegranate , citrus fruits, Green gram, Bitter gourd, Brinjal, Mustard, Sorghum.

[0081] In an embodiment of the present invention the present stable synergistic insecticidal composition can be applied as a foliar spray, soil drenching, seed dressing, application as paste of the targeted plants / trees, broadcasting, spraying, rubbing, atomizing, irrigating, evaporating, dusting, fogging, broadcasting, pouring, mist blowing, soil mixing, foaming, painting, spreading-on, drenching, dipping or drip irrigation.

[0082] In yet another embodiment of the present invention, the invention further provides the process for preparation of the said composition wherein, the said composition can be one or more of Capsule suspension (CS), Dispersible concentrate (DC), Dustable powder (DP), Powder for dry seed treatment (DS), Emulsifiable concentrate (EC), Emulsifiable granule (EG), Emulsion water-in-oil (EO), Emulsifiable powder (EP), Emulsion for seed treatment (ES), Emulsion oil-in-water (EW), Flowable concentrate for seed treatment (FS), Granules (GR), Micro -emulsion (ME), Oildispersion (OD), Oil miscible flowable concentrate (OF), Oil miscible liquid (OL), Oil dispersible powder (OP), Suspension concentrate (SC), Suspension concentrate for direct application (SD), Suspo-emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Spreading oil (SO), Water soluble powder (SP), Water soluble tablet (ST), Ultra-low volume (ULV) suspension, Tablet (TB), Ultra-low volume (ULV) liquid, Water dispersible granules (WG), Wettable powder (WP), Water dispersible powder for slurry seed treatment (WS), Water dispersible tablet (WT), a mixed formulation of CS and SC (ZC) or A mixed formulation of CS and SE (ZE) or a mixed formulation of CS and EW (ZW).

[0083] In yet another preferred embodiment of the present invention, the present synergistic insecticidal composition can be formulated as Suspension concentrate (SC), Suspo-emulsion (SE), Microemulsion (ME), Water dispersible granules (WG), Wettable powder (WP).

[0084] In yet another embodiment of the present invention, the present stable synergistic insecticidal composition can be applied to various plants including but not limited to Paddy, sugarcane, cotton, cabbage, cauliflower, tomato, chilli, brinjal, okra (Bhindi), soybean, Tea, Red Gram (Arhar / Tur), Chickpea, Grapes, Maize, Pigeon Pea, Groundnut, Bengal Gram, Black gram, Cucumber, Grains Millet, Pulses Dry Fruits, Nuts Spices & Oil Seeds ,turf and forage, cruciferous, cucurbits, grapevines, pepper, fodder beet, oil seed rape, pansy.

[0085] DETAILED DESCRIPTION OF THE INVENTION

[0086] In describing the embodiments of the invention, specific terminology is resorted for sake of clarity. However, it is not intended that the invention be limited to specific terms so selected and it is to be understood that each specific term includes all technical equivalents that operate in a similar manner to accomplish a similar purpose.

[0087] Discussed below are some representative embodiments of the present invention. The invention in its broader aspects is not limited to the specific details and representative methods.

[0088] All technical and scientific terms used herein have the same meanings as commonly understood by someone ordinarily skilled in the art to which the present subject matter belongs. The terminology used, in the present disclosure, is only for the purpose of explaining a particular embodiment and such terminology shall not be considered to limit the scope of the present disclosure.

[0089] Variations or modifications to the composition of this invention, within the scope of the invention, may occur to those skilled in the art upon reviewing the disclosure herein. Such variations or modifications are well within the spirit of this invention.

[0090] As used in the present disclosure, the forms "a,” "an," and "the" may be intended to include the plural forms as well, unless the context clearly suggests otherwise. Thus, for example, reference to a composition containing “a compound” includes a mixture of two or more compounds. It should also be noted that the term “or” is generally employed in its sense including “and / or” unless the content clearly dictates otherwise.

[0091] The terms "comprises," "comprising," “including,” and “having,” are open ended transitional phrases and therefore specify the presence of stated features, integers, steps, operations, elements, but do not forbid the presence or addition of one or more other features, integers, steps, operations, elements, components, and / or groups thereof. The particular order of steps disclosed in the method and process of the present disclosure is not to be construed as necessarily requiring their performance as described or illustrated. It is also to be understood that additional or alternative steps may be employed.

[0092] The expression of various quantities in terms of “% or “%” means the percentage by weight, relative to the weight of the total formulation or composition unless otherwise specified.

[0093] The term “active ingredient” (a.i.) or “active agent” used herein refers to that component of the composition responsible for control and killing of pest.

[0094] The terms “plants” and “vegetation” include, but are not limited to, germinant seeds, emerging seedlings, plants emerging from vegetative propagules, and established vegetation.

[0095] The term “crop” shall include a multitude of desired crop plants or an individual crop plant growing at a locus. The term “synergistic”, as used herein, refers to the combined action of two or more active agents blended together and administered conjointly that is greater than the sum of their individual effects.

[0096] “Bioactive amounts” as mentioned herein means that amount which, when applied for treatment of crops, is sufficient to give effect in such treatment.

[0097] The term “control” means to inhibit the ability of insect pests to survive, grow, feed and / or reproduce, or to limit the insect pests’ related damage or loss in crop plants. To “control” insect pests may or may not mean killing the insects although, it preferably means killing the insect pests.

[0098] The term “health of a plant” or “plant health” is defined as a condition of the plant and / or its products. As a result of the improved health; yield, plant vigour, quality and tolerance to abiotic or biotic stress is increased. As a result, the health of a plant is increased even in the absence of pest pressure.

[0099] Accordingly, in an especially preferred embodiment according to the invention, the health of a plant is increased both in the presence and absence of biotic or abiotic stress factors. The above identified indicators for the health condition of a plant may be interdependent or they may result from each other. An increase in plant vigor may for example result in an increased yield and / or tolerance to abiotic or biotic stress.

[0100] One indicator for the condition of the plant is the yield. “Yield” is to be understood as any plant product of economic value that is produced by the plant such as grains, fruits, vegetables, nuts, grains, seeds, wood (e.g. in the case of silviculture plants) or even flowers (e.g. in the case of gardening plants, ornamentals). The plant products may in addition be further utilized and / or processed after harvesting.

[0101] In an especially preferred embodiment of the invention, the yield of the treated plant is increased.

[0102] In another preferred embodiment of the invention, the yield of the plants treated according to the method of the invention, is increased synergistically.

[0103] According to the present invention, “increased yield” of a plant, in particular of an agricultural, silvicultural and / or horticultural plant means that the yield of a product of the respective plant is increased by a measurable amount over the yield of the same product of the plant produced under the same conditions, but without the application of the composition according to the invention. In another especially preferred embodiment of the invention, the plant vigour of the treated plant is increased. In another preferred embodiment of the invention, the plant vigour of the plants treated according to the composition of the present invention is increased synergistically.

[0104] Another indicator for the condition of the plant is the “quality” of a plant and / or its products. In an especially preferred embodiment of the invention, the quality of the treated plant is increased.

[0105] In another preferred embodiment of the invention, the quality of the plants treated according to the method of the invention, is increased synergistically.

[0106] The present invention includes within its scope, all possible salts, esters and derivatives of the active ingredients of the composition.

[0107] In accordance with an embodiment of the invention, there is provided a stable synergistic insecticidal composition comprising active ingredients present in the weight percentage range as given below: In one embodiment, the present invention provides a stable synergistic insecticidal composition comprising bioactive amounts of:

[0108] A) Compound of Formula I i.e. 3-mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3,3- dimethylbutyrate or its agrochemically acceptable salts, esters and derivatives;

[0109] B) Emamectin or its agrochemically acceptable salts, esters and derivatives; and C) Compound of Formula II i.e. 3-iodo-A'-(2-mesyl-l,l-dimethylethyl)-A-{4-[l,2,2,2-tetrafluoro- l(trifluoromethyl)ethyl]-c>-tolyl}phthalamide or its agrochemically acceptable salts, esters and derivatives.

[0110] In a preferred embodiment, the present invention provides a stable synergistic insecticidal composition comprising:

[0111] A) Compound of Formula I i.e. 3-mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3,3- dimethylbutyrate or its agrochemically acceptable salts, esters and derivatives, and is present in the range of 0.1 to 85% by weight of the composition;

[0112] B) Emamectin or its agrochemically acceptable salts, esters and derivatives, , and is present in the range of 0.1 to 85% by weight of the composition; and

[0113] C) Compound of Formula II i.e.3-iodo-A'-(2-mesyl- 1,1 -dimethylethyl)-A-{4-[ 1,2,2, 2-tetrafluoro- l(trifluoromethyl)ethyl]-c>-tolyl} phthalamide or its agrochemically acceptable salts, esters and derivatives, and is present in the range of 0.1 to 85% by weight of the composition.

[0114] In one another preferred embodiment, the present invention provides a stable synergistic insecticidal composition comprising:

[0115] A) Compound of Formula I i.e. 3-mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3,3- dimethylbutyrate or its agrochemically acceptable salts, esters and derivatives, and is present in range of 0.1 to 85% by weight of the composition;

[0116] B) Emamectin Benzoate, and is present in the range of 0.1 to 85% by weight of the composition; and

[0117] C) Compound of Formula II i.e.3-iodo-A'-(2-mesyl-l,l-dimethylethyl)-A-{4-[l,2,2,2-tetrafluoro- l(trifluoromethyl)ethyl]-c>-tolyl} phthalamide or its agrochemically acceptable salts, esters and derivatives, and is present in the range of 0.1 to 85% by weight of the composition.

[0118] In one another preferred embodiment, the present invention provides a stable synergistic Water dispersible granule insecticidal composition comprising:

[0119] A) Compound of Formula I i.e. 3-mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3,3- dimethylbutyrate or its agrochemically acceptable salts, esters and derivatives, and is present in the in the range of 0.1 to 85% by weight of the composition; B) Emamectin Benzoate, and is present in the range of 0.1 to 85% by weight of the composition; and

[0120] C) Compound of Formula II i.e.3-iodo-A'-(2-mesyl-l,l-dimethylethyl)-A-{4-[l,2,2,2-tetrafluoro- l(trifluoromethyl)ethyl]-c>-tolyl} phthalamide or its agrochemically acceptable salts, esters and derivatives, and is present in the range of 0.1 to 85% by weight of the composition.

[0121] In one another alternate embodiment, the present invention provides a stable synergistic water dispersible granule insecticidal composition comprising:

[0122] A) Compound of Formula I i.e. 3-mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3,3- dimethylbutyrate or its agrochemically acceptable salts, esters and derivatives, and is present as 38% by weight of the composition;

[0123] B) Emamectin Benzoate, and is present as 4.4 % % by weight of the composition; and

[0124] C) Compound of Formula II i.e.3-iodo-A'-(2-mesyl- 1,1 -dimethylethyl)-A-{4-[ 1,2,2, 2-tetrafluoro- l(trifluoromethyl)ethyl]-c>-tolyl} phthalamide or its agrochemically acceptable salts, esters and derivatives, and is present as 23.6% by weight of the composition.

[0125] In one another preferred embodiment, the present invention provides a stable synergistic Suspension Concentrate insecticidal composition comprising:

[0126] A) Compound of Formula I i.e. 3-mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3,3- dimethylbutyrate or its agrochemically acceptable salts, esters and derivatives, and is present in the range of 0.1 to 85% by weight of the composition;

[0127] B) Emamectin Benzoate, and is present in the range of 0.1 to 85% by weight of the composition; and

[0128] C) Compound of Formula II i.e.3-iodo-A'-(2-mesyl-l,l-dimethylethyl)-A-{4-[l,2,2,2-tetrafluoro- l(trifluoromethyl)ethyl]-c>-tolyl} phthalamide or its agrochemically acceptable salts, esters and derivatives, and is present in the range of 0.1 to 85% by weight of the composition.

[0129] In one another alternate embodiment, the present invention provides a stable synergistic Suspension Concentrate insecticidal composition comprising:

[0130] A) Compound of Formula I i.e. 3-mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3,3- dimethylbutyrate or its agrochemically acceptable salts, esters and derivatives, and is present as 21% by weight of the composition; B) Emamectin Benzoate, and is present as 1.5% by weight of the composition; and

[0131] C) Compound of Formula II i.e.3-iodo-A'-(2-mesyl-l,l-dimethylethyl)-A-{4-[l,2,2,2-tetrafluoro- l(trifluoromethyl)ethyl]-c>-tolyl} phthalamide or its agrochemically acceptable salts, esters and derivatives, and is present as 9.5% by weight of the composition.

[0132] In one another alternate embodiment, the present invention provides a stable synergistic water dispersible granule insecticidal composition comprising:

[0133] A) Compound of Formula I i.e. 3-mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3,3- dimethylbutyrate or its agrochemically acceptable salts, esters and derivatives, and is present as 21% by weight of the composition;

[0134] B) Emamectin Benzoate, and is present as 1.5% by weight of the composition; and

[0135] C) Compound of Formula II i.e.3-iodo-A'-(2-mesyl- 1,1 -dimethylethyl)-A-{4-[ 1,2,2, 2-tetrafluoro- l(trifluoromethyl)ethyl]-c>-tolyl} phthalamide or its agrochemically acceptable salts, esters and derivatives, and is present as 9.5% by weight of the composition.

[0136] In another embodiment of the present invention, the synergistic insecticidal composition of the present invention further comprises one or more agrochemically acceptable excipients including but not limited to the group comprising surfactant(s), dispersing agent(s), anti-freezing agent(s), emulsifier(s), anti-foaming agent / defoamer(s), wetting agent(s), antimicrobial / anti-bacterial agent(s), thickening agent / thickener(s), quick coating agent(s) or sticking agents / sticker(s), spreader(s), binder(s), pH-adjusting agent(s), anti-caking agent(s), adjuvant(s), filler(s) / suspension aid(s), colorant(s), carrier(s), buffering agent(s), rheology modifier(s), solvent(s), co-solvent(s) or a combination thereof. Additional components may also be included, e.g., protective colloids, carriers, adhesives, thixotropic agents, penetration agents, stabilisers, sequestering agents. More generally, the active materials can be combined with any solid or liquid carrier / additive, which complies with usual formulation techniques.

[0137] An adjuvant used in the present invention is any material that is added to an agrochemical formulation to enhance or modify the performance of the formulation. An adjuvants used in the present invention to make it a safer to ecological environmental, having low toxicity and having no phytotoxicity effects on any part of the plant. In another preferred embodiments of the present invention, surfactants / dispersing agent is selected from the group comprising Sodium diisopropyl naphthlene sulphonate, sodium lauryl sulphate, Sodium ligno sulphonate, sodium salt of naphthalene sulfonate condensate, Polyarylphenyl ether phosphate, tristyryl phenol, ethylated / Acrylic Copolymer / Ethoxylated Tristryl phenol Sulphate, Naphthalene sulfonic acid, sodium salt condensate with formaldehyde, Ethoxylated oleyl cetyl alcohol, Polyalkelene glycol ether, Ethoxylated Fatty alcohol, sodium polycarboxylate, sodium lignosulphonates, calcium ligno sulphate, Poly aryl phenyl ether phosphate, Methyl naphthalene sulfonic acid, polymer with formaldehyde , sodium salt, Tristyrylphenol Ethoxylate Amine salt of phosphate, tristyryl phenol ethylate, Acrylic Copolymer, Ethoxylated Tristryl phenol Sulphate, Naphthalene sulfonic acid, sodium salt condensate with formaldehyde, Ethoxylated oleyl cetyl alcohol, Polyalkelene glycol, naphthalene sulphonate formaldehyde condensates, tristyrylphenolethoxylate phosphate, sulfonated aromatic polymer, sodium salt, ethoxylated fatty alcohol, alkyl ethoxylates, polymeric dispersant, acrylic graft copolymer, polyalkoxy ethers, EO- PO block copolymers, and graft copolymers, or mixtures thereof and present in the range of 0.1- 20% by weight of the composition.

[0138] In another preferred embodiments of the present invention, the solvents and co-solvents are selected from the group comprising heavy aromatic hydrocarbon, N-methyl pyrollidone(NMP), Di-methyl sulfoxide(DMSO), N- alcohol, alkyl amide, vegetable oil, mineral oil, aromatic solvents, solvent naptha (solvent C-IX) , water or mixtures thereof and present in the range of 0.1- 90% by weight of the composition.

[0139] In another preferred embodiments of the present invention, emulsifiers are selected from the group comprising ionic emulsifier, non-ionic emulsifier or Castor oil or its ethoxylates, tall oil or its ethoxylates, Calcium alkyl benzene sulfonate, polymeric dispersant or mixtures thereof and present in the range of 0.1-15% by weight of the composition

[0140] In another preferred embodiments of the present invention, anti-freezing agent is selected from the group comprising glycols, monoethylene glycol, diethylene glycol, polyethylene glycols, methoxypolyethylene glycols, propylene glycol, polypropylene glycols, polybutylene glycols, glycerine, ethylene glycol and mixtures thereof and present in the range of 0.1-10% by weight of the composition. In another preferred embodiments of the present invention, antifoaming agent is selected form the group comprising silicon emulsion based anti-foam agents, Siloxane polyalkyleneoxide, trisiloxane ethoxylates, Polydimethylsiloxane emulsion and mixtures thereof and present in the range of 0.1-10% by weight of the composition.

[0141] In another preferred embodiments of the present invention, wetting agent is selected form the group comprising Sodium salt of sulphated product, sodium lauryl sulphate, sodium dioctylsulphosuccinate, Tristyrylphenolethoxylate non-ionic emulsifier, mixture of non-ionic surfactants & Alkoxylated Alcohol, Block copolymer, alkyl phenol ethoxylates, and aliphatic alcohol ethoxylates, their salts and mixtures thereof and present in the range of 0.1-10% by weight of the composition.

[0142] In another preferred embodiments of the present invention, antimicrobial / anti-bacterial agent is selected from the group comprising propionic acid and its sodium salt; sorbic acid and its sodium or potassium salts; benzoic acid and its sodium salt, hydroxy benzoic acid sodium salt, methyl p- hydroxy benzoate, and biocide such as sodium benzoate, sodium o-phenyl phenate, 1,2- benzisothiazoline-3-one, 2-methyl-4-isothiazolin-3-one, 5-chloro-2-methyl-4-isothiazolin-3-one, potassium sorbate, parahydroxy benzoates, Benzisothiazolin-3-one, formaldehyde or mixtures thereof and present in the range of 0.01-10% by weight of the composition.

[0143] In another preferred embodiments of the present invention, thickening agent is selected from the group comprising montmorillonite, bentonite clay, magnesium aluminium silicate, attapulgite, natural extracts of seeds and seaweeds, guar gum, locust bean gum, carrageenam, xanthan gum, alginates, polysaccharides, methyl cellulose, carboxymethyl cellulose (CMC), hydroxyethyl cellulose (HEC), bentonite clay, modified starches, polyacrylates, polyvinyl alcohol and polyethylene oxide or mixtures thereof and present in the range of 0.1-10% by weight of the composition.

[0144] In another preferred embodiments of the present invention, filler is selected from the group comprising Silicon Dioxide, bentonite clay, china clay, precipitated silica, kaolin, talcum powder, starch, urea formaldehyde resin and diatomaceous earth, Lactose monohydrate and mixtures thereof and present in the range of 0.1 -90% by weight of the composition.

[0145] In another preferred embodiments of the present invention, adjuvants are selected from group comprising Silicone Ethoxylated Oil, Polyvinyl Pyrrolidone, Polyvinyl Alcohol or mixtures thereof and present in the range of 0.1-10% by weight of the composition.

[0146] The composition of the present invention can also comprise or may be applied together and / or sequentially with further active compounds. These further compounds can be selected from fertilizers or micronutrient donors or microorganisms or other preparations that influence plant growth, such as inoculants (e.g. a strain of nitrogen-fixing bacteria), and plant inducers.

[0147] In yet another embodiment, the composition according to the invention can be applied to any and all developmental stages of insect pests, such as egg, nymph, larva, pupa, and adult. The insect pests may be controlled by contacting the target insect pest, habitat, breeding ground or its locus with a bioactive amount of the novel and inventive composition of the present invention.

[0148] In yet another embodiment of the present invention, the insecticidal composition is formulated as but not limited to Capsule suspension (CS), Dispersible concentrate (DC), Dustable powder (DP), Powder for dry seed treatment (DS), Emulsifiable concentrate (EC), Emulsifiable granule (EG), Emulsion water-in-oil (EO), Emulsifiable powder (EP), Emulsion for seed treatment (ES), Emulsion oil-in-water (EW), Flowable concentrate for seed treatment (FS), Granules (GR), Microemulsion (ME), Oil-dispersion (OD), Oil miscible flowable concentrate (OF), Oil miscible liquid (OL), Oil dispersible powder (OP), Suspension concentrate (SC), Suspension concentrate for direct application (SD), Suspo-emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Spreading oil (SO), Water soluble powder (SP), Water soluble tablet (ST), Ultra-low volume (ULV) suspension, Tablet (TB), Ultra-low volume (ULV) liquid, Water dispersible granules (WG), Wettable powder (WP), Water dispersible powder for slurry seed treatment (WS), Water dispersible tablet (WT), a mixed composition of CS and SC (ZC) or a mixed composition of CS and SE (ZE) or a mixed composition of CS and EW (ZW). In yet another embodiment of the present invention, the invention further provides the process for preparation of the said insecticidal composition wherein, the said composition can be one or more of Capsule suspension (CS), Dispersible concentrate (DC), Dustable powder (DP), Powder for dry seed treatment (DS), Emulsifiable concentrate (EC), Emulsifiable granule (EG), Emulsion water- in-oil (EO), Emulsifiable powder (EP), Emulsion for seed treatment (ES), Emulsion oil-in-water (EW), Flowable concentrate for seed treatment (FS), Granules (GR), Micro-emulsion (ME), Oildispersion (OD), Oil miscible flowable concentrate (OF), Oil miscible liquid (OL), Oil dispersible powder (OP), Suspension concentrate (SC), Suspension concentrate for direct application (SD), Suspo-emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Spreading oil (SO), Water soluble powder (SP), Water soluble tablet (ST), Ultra-low volume (ULV) suspension, Tablet (TB), Ultra-low volume (ULV) liquid, Water dispersible granules (WG), Wettable powder (WP), Water dispersible powder for slurry seed treatment (WS), Water dispersible tablet (WT), a mixed composition of CS and SC (ZC) or a mixed composition of CS and SE (ZE) or a mixed composition of CS and EW (ZW).

[0149] According to another embodiment of the present invention, there is also a process provided for the preparation of stable synergistic insecticidal composition comprising A) Compound of Formula I i.e. 3-mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3, 3 -dimethylbutyrate or its agrochemically acceptable salts, esters and derivatives;

[0150] B) Emamectin or its agrochemically acceptable salts, esters and derivatives; and

[0151] C) Compound of Formula II i.e. 3-iodo-A'-(2-mesyl- l , 1 -dimethylethyl)W-{4-[l ,2,2,2-tetrafluoro- l(trifluoromethyl)ethyl]-c>-tolyl}phthalamide or its agrochemically acceptable salts, esters and derivatives.

[0152] In one embodiment, the composition according to the present invention acts synergistically to control insect pests in various crops.

[0153] The composition of the present invention also provides control of diseases caused by a broad spectrum of insect plant pathogens preventatively or curatively by applying an effective amount of the composition either pre-or post-infection. Plant disease control is ordinarily accomplished by applying an effective amount of a synergistic composition of the present invention either pre-or post-infection, to the portion of the plant to be protected such as the roots, stems, foliage, fruit, seeds, tubers or bulbs, or to the media (soil or sand) in which the plants to be protected are growing. The composition can also be applied to the seed to protect the seed and seedling.

[0154] Through the insecticidal composition of present invention, the number of applications to control wide range of insect pests appearing at the same time is minimised. The composition of present invention is highly safe to the user and to the environment. The composition offers the user a single homogenous application eliminating the need for tank mix. The composition also is cost-effective as it provides much greater simultaneous control and can be used in a variety of crops with a broader spectrum of protection.

[0155] In particular, it has now been found, surprisingly that, for example, the insecticidal activity of the composition of present invention, compared with the insecticidal activity of individual components, is synergistic. In fact, various advantageous properties associated with the compositions according to the invention, include but are not limited to: knock down effect on insect pests at all developmental stages, with no phytotoxicity and enhanced shelf life, stability of the composition.

[0156] In order that the present invention may be more readily understood, reference will now be made, by way of examples, to the following description. It will be understood that the specification and examples are illustrative but not limitative of the present invention and that other embodiments within the spirit and scope of the invention will suggest themselves to those skilled in the art. Other embodiments can be practiced that are also within the scope of the present invention. The following illustrations of examples are intended to illustrate a stable synergistic insecticidal composition, but in no way limit the scope of the present invention.

[0157] Compound of Formula I: 3-mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3, 3 -dimethylbutyrate or its agrochemically acceptable salts, esters and derivatives Compound of Formula II: 3-iodo-A'-(2-mesyl-l,l-dimethylethyl)-A-{4-[l,2,2,2-tetrafluoro- l(trifluoromethyl)ethyl]-c>-tolyl} phthalamide or its agrochemically acceptable salts, esters and derivatives Examples

[0158] Example 1

[0159] Compound of Formula 121% + Emamectin 1.50% + Compound of Formula II 9.50% WG

[0160] Manufacturing Process

[0161] Took china clay in the ribbon blender for mixing. To this added Silica powder, Sodiumdiisopropyl naphthlene sulphonate, Sodium Lauryl Sulphate, Sodium lignosulphonate, sodium salt of naphthalene sulfonate condensate, polymeric dispersant, Lactose monohydrate, Compound of Formula I technical, Emamectin technical and Compound of Formula II technical and mixed well. Continued to mix this till the material is completely homogenised. Allowed to pass the premix through the Airjet mill at 6 to 7 kg / cm2 of grinding pressure and 100 to 150 kg / hr feeding rate so as get a particle size of D90 less than 10 microns. The grinded material was collected in post blender.

[0162] Extrusion process

[0163] Into the post blender the solution of water and Polydimethylsiloxane emulsion added by means of spraying and dough was prepared. This dough was mixed well to get a well hydrated dough for extrusion. This dough then allowed to pass through the screw valve fitted with post blender and then passed through basket extruder.

[0164] Drying Process

[0165] These wet extruded granules then passed through VFBG (vibro fluid bed drier) which was brought to a consistent temperature of 50°C prior to drying of wet granules. These granules are checked for moisture content which should not more than 3%. Once the parameter got set then the process continued.

[0166] Sieving and packing The dried granule was passed through vibro siever machine to separate any lumps or dust and desired size granules were collected and packed.

[0167] Stability Data

[0168] Compound of Formula 121 % + Emamectin Benzoate 1.5% + Compound of Formula II 9.5 WG

[0169] Example 2

[0170] Compound of Formula 121 % + Emamectin Benzoate 1.5% + Compound of Formula II 9.5% SC

[0171] Manufacturing Process:

[0172] Pre- mixing

[0173] 1. Charged D.M water into a clean reactor and stirred then added propylene glycol, acrylic Graft copolymer, polyalkoxy ethers, methyl naphthalene sulfonic acid, polymer with formaldehyde, sodium salt, Poly dimethyl siloxane and l,2-Benzisothiazolin-3-one, further allowed it to mix well to make a homogeneous solution,

[0174] 2. To the above solution further added Spiromesifen technical, Emamectin technical and Flubendiamide technical and mixed well to form a homogeneous slurry.

[0175] Wet-milling process

[0176] 1. Allowed to pass the above prepared premix through bead mill at 400 to 500 Ltr / hr feed rate so as get a desired particle size.

[0177] 2. The grinded material was collected in post blender.

[0178] Post- Mixing

[0179] 1. The milled slurry was collected into the post blender and to this pre hydrated xantham gum was added.

[0180] 2. Mixed well till the slurry attains right viscosity

[0181] 3. Packed the formulation into HDPE bottles. Stability Data

[0182] Compound of Formula 121 % + Emamectin Benzoate 1.5% + Compound of Formula II 9.5% SC Bio-Efficacy Data

[0183] Evaluation of synergistic effect of insecticidal composition of the present invention

[0184] A synergistic effect of two or more products exists whenever the action of an active ingredient combination is greater than the sum of the actions of the individual components. Synergism was calculated by using Colby’s method (Weeds, vol. 15 No. 1 (Jan 1967), pp. 20-2.

[0185] The synergistic action expected for a given combination of two active components can be calculated as follows:

[0186] XY

[0187] E = (X + Y) - 100

[0188] The synergistic action expected for a given combination of three active components can be calculated as follows: (XY+YZ+XZ) (XYZ)

[0189] E = (X + Y + Z) - + -

[0190] 100 10000

[0191] Where:

[0192] E represents expected percentage of pesticidal control for the combination of the two or three actives ingredients at defined doses (for example equal to x, y and z, respectively).

[0193] X is the percentage of pesticidal control observed by the compound (Compound of Formula I) at a defined dose (equal to x).

[0194] Y is the percentage of pesticidal control observed by the compound (Emamectin Benzoate) at a defined dose (equal to y).

[0195] Z is the percentage of pesticidal control observed by the compound (Compound of Formula II) at a defined dose (equal to z).

[0196] When the percentage of pesticidal control observed for the combination is greater than the expected percentage, there is a synergism effect.

[0197] Observed control (%) Ratio = -

[0198] Expected control (%)

[0199] Ratio of O / E > 1 , synergism observed

[0200] The present invention is illustrated by way of examples, the examples are meant for illustrative purposes and should not be construed as limiting.

[0201] Experiment for Synergistic activity of composition of present invention:

[0202] Details of experiment on Chilli crop:

[0203] Field experiment for synergistic activity of Compound of Formula I, Emamectin Benzoate and Compound of Formula II for the control of Fruit borer and yellow mite pest in chilli crop was conducted at farmer field, Udaipur (Rajasthan). To evaluate the synergistic effect, Chilli (Variety: Kashi Anmol) crop was sown in 4 m x 5 m plots maintaining 30 cm x 30 cm plant distance with three replications and in Randomized Block Design (RBD).The treatments were applied as foliar application at the ETL level of insect population. Each active component was applied at recommended doses in different ternary and binary combinations. Solo components were also taken for comparison. The treatment details are as under: The treatments T1 to T28 were used as foliar application whereas no treatment was done for T29 control treatment. Observations for Fruit borer Helicoverpa armigera) and yellow mite (Polyphagotarsonemus I at u ) were recorded at Before spray, 7 and 15 days after sprays by observing 10 random plants per plot and based on number of fruit damaged and reduction over control was calculated and yellow mite per cent control was calculated over control. Based on the per cent reduction in fruit damaged and yellow mite population the Expected control was calculated and compared with Observed control. The results of the trial have been presented here under in Table 1. Table 1: Synergistic effect of of the present invention (Compound of Formula I + Emamectin Benzoate + Compound of Formula II) against Fruit borer and yellow mite in Chilli crop

[0204] It is clearly evident from the data shown in above Table 1 for per cent reduction of fruit damaged and per cent control of yellow mite in Chilli crop that the ternary combination composition of the present invention comprising Compound of Formula I, Emamectin Benzoate and Compound of Formula II T1 to T4 are synergistic for both Insect-pest control with > 1 Colby’s Ratio. The binary combination of two insecticides (Emamectin Benzoate and Compound of Formula II) T13 to T16 is compatible but antagonistic effect for the control of yellow mite. The binary combination of one acaricide and one insecticide (Compound of Formula I and Emamectin Benzoate and Compound of Formula I and Compound of Formula II) T5 to T8 and T9 to T12 are more effective to control fruit borer and for yellow mite control as compared to binary combination of Emamectin Benzoate and Compound of Formula II T13 to T16. All binary combinations are shown additive effect for control of both insect-pest for control in compared to ternary combinations.

[0205] Experiment for Bio-efficacy evaluation of combination product of present invention:

[0206] For the ternary and binary combination based on Compound of Formula I, Emamectin Benzoate and Compound of Formula II evaluation under field conditions, the basic test composition as Compound of Formula I, Emamectin Benzoate and Compound of Formula II. For ternary combination, Compound of Formula 121% + Emamectin Benzoate 1.5% + Compound of Formula II 9.5% SC was used and for binary combinations, Compound of Formula I 21% + Emamectin Benzoate 1.5% SC, Compound of Formula I 21% + Compound of Formula II 9.5% SC and Emamectin Benzoatel.5% + Compound of Formula II 9.5% SC and solo formulations of Compound of Formula I 21% SC, Emamectin Benzoatel.5% SC and Compound of Formula II 20% WG were used. The market samples Compound of Formula I 22.90% SC, Emamectin benzoate 5% SG and Compound of Formula II 20% WG were used for comparison.

[0207] Evaluation of the combination product of the present invention on Chilli crop.

[0208] The synergistic composition of the present invention Compound of Formula 1 21% + Emamectin Benzoatel.5% + Compound of Formula II 9.5% SC was evaluated on Chilli crop variety Kashi Anmol at a farmer field, Udaipur. The experiment plots are design in Randomized Block Design (RBD) with three replications maintaining a distance of 30 cm x 30 cm between plants and rows.

[0209] The observations were recorded for the following objectives.

[0210] Objectives:

[0211] 1. Bio-efficacy evaluation against fruit borer on Chilli crop

[0212] 2. Bio-efficacy evaluation against yellow mite on Chilli crop

[0213] 3. Bio-efficacy evaluation based on per cent reduction in fruit damaged over control.

[0214] 4. Bio-efficacy evaluation based on percent reduction in yellow mite population.

[0215] 5. Bio-efficacy evaluation based on crop yield and percent increase over control.

[0216] 6. Phytotoxicity evaluation on Chilli crop

[0217] 7. Impact of treatments on natural enemies (spiders and coccinellids) in Chilli crop

[0218] 8. Economics of treatments based on Cost: Benefit Ratio Treatment details:

[0219] Methodology: The treatments T1 to T18 and T20 were used as foliar application whereas no treatment was done for T19 untreated control plots. The treatments were applied as foliar application at the ETL level of insect population. Each active component was applied at two doses in different ternary and binary combinations. Solo components were also taken for comparison.

[0220] 5 Observations for Fruit borer Helicoverpa armigera) and yellow mite (Polyphagotarsonemus latus) were recorded at Before spray, 7 and 15 days after sprays by observing 10 random plants per plot and based on number of fruit damaged and reduction over control was calculated, and yellow mite per cent control was calculated over control. The green chilli yield was recorded at different picking as per harvest. The observations for natural enemies in crop ecosystem at Before, 10 7 and 15 days after crop sowing and phytotoxicity to Chilli crop at 0, 3, 7, 10 & 15 days after spray were also recorded. Based on treatment application cost, market price of produce and net profit, the Cost: Benefit Ratio was calculated for the economics of ternary combination treatments. The data were subjected to statistically analysis of variance. Results are presented in Table 3, 4, 5. 6 and 7.

[0221] 15 Results:

[0222] Table 3: Field bio-efficacy evaluation of Compound of Formula I 21 % + Emamectin Benzoatel.5% + Compound of Formula II 9.5% SC against Fruit borer of chilli crop

[0223] DAS - Days after spray

[0224] Table 4: Field bio-efficacy evaluation of Compound of Formula I 21 % + Emamectin Benzoatel.5% + Compound of Formula II 9.5% SC against Yellow mite of chilli crop.

[0225] DAS - Days after spray

[0226] Table 5: Field bio-efficacy evaluation of Compound of Formula I 21 % + Emamectin Benzoatel.5% + Compound of Formula II 9.5% SC based on yield of chilli crop.

[0227] Table 6: Field bio-efficacy evaluation of Compound of Formula I 21 % + Emamectin Benzoatel.5% + Compound of Formula II 9.5% SC for effect on natural enemies on Chilli crop.

[0228] DAS - Days after Spray

[0229] Table 7: Phytotoxicity evaluation of Compound of Formula I 21 % + Emamectin

[0230] Benzoatel.5% + Compound of Formula II 9.5% SC on Chilli crop.

[0231]

[0232] From the examples above, it can be clearly seen that the Composition of the present invention is superior for controlling the Fruit borer Helicoverpa armigera) at 7 and 15 days after spray (Table 3) and for controlling yellow mite (Polyphagotarsonemus latus) at 7 and 15 days after spray (Table 5 4) in Chilli crop as compared to the binary composition and solo component comprising at different dosage levels. Other registered formulated products available in the market, Compound of Formula I 22.90 % SC, Emamectin benzoate 5 % SG and Compound of Formula II 20 % WG evaluated were next in order of effectiveness after ternary combination products. The yield of Chilli crop also improved in the ternary combination of Compound of Formula I 21% + Emamectin 0 Benzoatel.5% + Compound of Formula II 9.5% SC as compared to binary and solo components (Table 5). One of the reasons of higher green chilli yield may be due to better control of both insect pests. The Cost: Benefit Ratio revealed that ternary combination Compound of Formula 1 21% + Emamectin Benzoatel.5% + Compound of Formula II 9.5% SC @ 500ml / ha was most economical with higher Cost: Benefit Ratio as compared to other binary and solo treatments (Table 5). No adverse effect of all the treatments was observed on the prevailing natural enemies (spiders and coccinellids) in Chilli crop ecosystem at 7 and 15 days after spray (Table 6).

[0233] The disclosed combination Compound of Formula I 21% + Emamectin Benzoatel.5% + Compound of Formula II 9.5% SC @ 500 ml, 600 ml and 1200 ml / ha further showed no phytotoxicity in the Chilli crop even after 0, 3, 5, 7, 10 and 15 days after spray (Table 7).

[0234] Experiment for Synergistic activity of insecticidal composition of present invention:

[0235] Details of experiment on Tomato crop:

[0236] Field experiment for synergistic activity of Compound of Formula I, Emamectin Benzoate and Compound of Formula II for the control of Fruit rot disease and mite pest in Tomato crop was conducted at farmer field, Nashik (Maharashtra).

[0237] To evaluate the synergistic effect, Tomato (Variety Abhinav) crop was sown in 5 m x 5 m plots at 90 cm x 20 cm plant distance with three replications and in Randomized Block Design (RBD).. The treatments were applied as foliar application in the form of WG formulation @ 250 ml / ha. Each active component was applied at recommended dose in different ternary and binary combinations, Solo component was also taken for comparison. The treatment details are as under:

[0238] The treatments T1 to T28 were used as foliar application whereas no treatment was done for T29 control treatment. All the treatments were applied at the appearance of insect-pest in the plots. Observations for Fruit borer (Helicoverpa armigera) and mite (Tetranychus urticae) were recorded at Before spray, 7 and 15 days after sprays by observing 10 random plants per plot and based on number of fruit damaged and reduction over control was calculated and mite per cent control was calculated over control. Based on the per cent reduction in fruit damaged and mite population the Expected control was calculated and compared with Observed control. The results of the trial have been presented here under in Table 8. Table 8: Synergistic effect of combination product of the present invention (Compound of Formula I + Emamectin Benzoate + Compound of Formula II) against Fruit borer and mite in Tomato crop. T29 | Untreated check

[0239] It is clearly evident from the data shown in above Table 1 for per cent fruit rot disease control and per cent mite pest control in Tomato crop that the ternary combination composition of the present invention comprising Compound of Formula I, Emamectin Benzoate and Compound of Formula II T1 to T4 are synergistic for both insect and mites control with > 1 Colby’s Ratio. The binary composition of two insecticides (Emamectin Benzoate and Compound of Formula II) T13 to T16 is compatible but antagonistic effect for the control of mite being insecticides. The binary composition of one acaricide and one insecticide (Compound of Formula I and Emamectin Benzoate and Compound of Formula I and Compound of Formula II) T5 to T8 and T9 to T 12 are more effective to control fruit borer and for mite control as compared to binary composition of Emamectin Benzoate and Compound of Formula II T13 to T16. All binary compositions are shown additive effect for control of both insect-pest for control in compared to ternary compositions.

[0240] Experiment for Bio-efficacy evaluation of combination product of present invention:

[0241] For the ternary and binary combination based on Compound of Formula I, Emamectin Benzoate and Compound of Formula II evaluation under field conditions, the basic test composition as Compound of Formula I, Emamectin Benzoate and Compound of Formula II were manufactured specifically by the inventor. For ternary combination, Compound of Formula 138% + Emamectin Benzoate 4.4% + Compound of Formula II 23.6% WG was used and for binary combinations, Compound of Formula I 38% + Emamectin Benzoate 4.4% WG, Compound of Formula I 38% + Compound of Formula II 23.6% WG and Emamectin Benzoate 4.4% + Compound of Formula II 23.6% WG and solo formulations of Compound of Formula 138%WG, Emamectin Benzoate 4.4% WG and Compound of Formula II 23.6% WG were used. The market samples Compound of Formula I 22.90% SC, Emamectin benzoate 5% SG and Compound of Formula II 20% WG were used for comparison.

[0242] Evaluation of the combination product of the present invention on Tomato The synergistic insecticidal composition of the present invention Compound of Formula I 38% + Emamectin Benzoate 4.4% + Compound of Formula II 23.6% WG was evaluated on Tomato crop variety Abhinav at a farmer field, Nashik, Maharashtra. The treatments application was done on at initiation of insect-pest in plots sown in Randomized Block Design (RBD) with three replications maintaining a distance of 60 cm x 45 cm between plants and rows.

[0243] The observations were recorded for the following objectives.

[0244] Objectives:

[0245] 1. Bio-efficacy evaluation against fruit rot disease on Tomato crop 2. Bio-efficacy evaluation against Mite on Tomato crop

[0246] 3. Bio-efficacy evaluation based on per cent reduction in fruit damaged over control.

[0247] 4. Bio-efficacy evaluation based on percent reduction in mite population

[0248] 5. Bio-efficacy evaluation based on crop yield

[0249] 6. Phytotoxicity evaluation on Tomato crop 7. Impact of treatments on natural enemies (spiders and coccinellids) in Tomato crop

[0250] 8. Economics of treatments based on Cost; Benefit Ratio

[0251] Treatment details:

[0252] Methodology:

[0253] The treatments T1 to T18 and T20 were used as foliar application whereas only water spray was done for T 19 control treatment. The treatments were applied as foliar application at the ETL level of insect population. Each active component was applied at two doses in different ternary and binary compositions. Solo components were also taken for comparison.

[0254] Observations for Fruit borer (Helicoverpa armigera) and mite (Tetranychus urticae) were recorded at Before spray, 7 and 15 days after sprays by observing 10 random plants per plot and based on number of fruit damaged and reduction over control was calculated and mite per cent control was calculated over control. The fruit yield tomato was recorded at different picking as per harvest.

[0255] The observations for natural enemies in crop ecosystem at Before, 7 and 15 days after crop sowing and phytotoxicity to tomato crop at 0, 3, 7, 10 & 15 days after spray were also recorded. Based on treatment application cost, market price of produce and net profit, the Cost: Benefit Ratio was calculated for the economics of ternary composition treatments. The data were subjected to statistically analysis of variance. Results are presented in below provided Tables.

[0256] Results:

[0257] Table 9: Field bio-efficacy evaluation of Compound of Formula I 38% + Emamectin

[0258] Benzoate 4.4% + Compound of Formula II 23.6% WG against Fruit borer of Tomato crop.

[0259] DAS - Days after spray

[0260] Table 10: Field bio-efficacy evaluation of Compound of Formula I 38% + Emamectin Benzoate 4.4% + Compound of Formula II 23.6% WG against mite of Tomato crop.

[0261] DAS - Days after spray Table 11: Field bio-efficacy evaluation of Compound of Formula I 38% + Emamectin Benzoate 4.4% + Compound of Formula II 23.6% WG based on yield of Tomato crop.

[0262] Table 12: Field bio-efficacy evaluation of Compound of Formula I 38% + Emamectin Benzoate 4.4% + Compound of Formula II 23.6% WG for effect on natural enemies on tomato crop.

[0263] DAS - Days after spray

[0264] Table 13: Phytotoxicity evaluation of Compound of Formula I 38% + Emamectin Benzoate 4.4% + Compound of Formula II 23.6% WG on Tomato crop.

[0265]

[0266] From the tables , it can be clearly seen that the combination of the present invention Compound of Formula I 38% + Emamectin Benzoate 4.4% + Compound of Formula II 23.6% WG is superior for Fruit borer (Helicoverpa armigera) at 7 and 15 days after spray (Table 2) and for controlling

[0267] 5 mite (Tetranychus urticae) at 7 and 15 days after spray (Table 3) in Tomato crop as compared to the binary composition and solo component comprising at different dosage levels. Other registered formulated products available in the market, Compound of Formula I 22.90 % SC, Emamectin benzoate 5 % SG and Compound of Formula II 20 % WG evaluated were next in order of effectiveness after ternary composition products. The yield of tomato crop also improved in the 0 ternary composition of Compound of Formula I 38% + Emamectin Benzoate 4.4% + Compound of Formula II 23.6% WG as compared to binary and solo components (Table 4). One of the reasons of higher tomato yield may be due to better control of both insect pest. The Cost: Benefit Ratio revealed that ternary composition Compound of Formula I 38% + Emamectin Benzoate 4.4% + Compound of Formula II 23.6% WG @ 250gm / ha was most economical with higher Cost: Benefit 5 Ratio as compared to other binary and solo treatments (Table 11). No adverse effect of all the treatments was observed on the prevailing natural enemies (spiders and coccinellids) in tomato crop ecosystem at 7 and 15 days after spray (Table 12).

[0268] The disclosed composition Compound of Formula I 38% + Emamectin Benzoate 4.4% + Compound of Formula II 23.6% WG @ 250gm, 300gm and 500 gm / ha further showed no 0 phytotoxicity in the tomato crop even after 0, 3, 5, 7, 10 and 15 days after spray (Table 13).

[0269] It is evident from the above tables of examples that the combination composition of the present invention Compound of Formula I, Emamectin Benzoate and Compound of Formula II resulted in good control in fruit borer and mite in Tomato crop with higher respective yields as compared to the reference standard products (binary compositions and solo products). The Cost: Benefit Ratio also showed that ternary combination of Compound of Formula I, Emamectin Benzoate and Compound of Formula II was most economical with higher Cost: Benefit Ratio as compared to other binary and solo treatments. Further, the composition of present invention is resulted synergistic.

[0270] From the above investigations, it will be observed that numerous modifications and variations can be effectuated without departing from the true spirit and scope of the novel concepts of the present invention. It is to be understood that no limitations with respect to the specific embodiments illustrated is intended or should be inferred. It should be understood that all such modifications and improvements have been deleted herein for the sake of conciseness and readability but are properly within the scope of the following claims.

Claims

I CLAIM

1. A stable synergistic insecticidal composition comprising: a) Compound of Formula I i.e. 3-mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3,3- dimethylbutyrate or its agrochemically acceptable salts, esters and derivatives; b) Emamectin or its agrochemically acceptable salts, esters and derivatives; c) Compound of Formula II i.e. 3-iodo-A'-(2-mesyl-l,l-dimethylethyl)-A-{4-[ 1 ,2,2,2-tetrafluoro- 1 (trifluoromethyl)ethyl] -o-tolyl Jphthalamide or its agrochemically acceptable salts, esters and derivatives.

2. The stable synergistic insecticidal composition as claimed in claim 1 comprising: a) Compound of Formula I i.e. 3-mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3,3- dimethylbutyrate or its agrochemically acceptable salts, esters or its derivatives and is present in the range of 0.1-85% by weight of the composition. b) Emamectin or its agrochemically acceptable salts, esters or its derivatives and is present in the range of 0.1-85% by weight of the composition. c) Compound of Formula II i.e. 3-iodo-A'-(2-mesyl-l,l-dimethylethyl)-A-{4-[ 1 ,2,2,2-tetrafluoro- 1 (trifluoromethyl)ethyl] -o-tolyl Jphthalamide or its agrochemically acceptable salts, esters or its derivatives and is present in the range of 0.1-85% by weight of the composition.

3. The stable synergistic insecticidal composition as claimed in claim 1 and 2 further comprising one or more agrochemically acceptable excipients.

4. The stable synergistic insecticidal composition as claimed in claim 3, wherein the agrochemically acceptable excipients are selected from the group comprising surfactant / dispersing agent, emulsifiers, solvents, co-solvents, anti-freezing agent, anti-foaming agent, wetting agent,antimicrobial / anti-bacterial agent, thickening agent / thickener, fillers, adjuvants or mixtures thereof.

5. The stable synergistic insecticidal composition as claimed in claim 4 wherein the surfactants / dispersing agent is selected from the group comprising Sodium diisopropyl naphthlene sulphonate, sodium lauryl sulphate, Sodium ligno sulphonate, sodium salt of naphthalene sulfonate condensate, Polyarylphenyl ether phosphate, tristyryl phenol, ethylated / Acrylic Copolymer / Ethoxylated Tristryl phenol Sulphate, Naphthalene sulfonic acid, sodium salt condensate with formaldehyde, Ethoxylated oleyl cetyl alcohol, Polyalkelene glycol ether, Ethoxylated Fatty alcohol, sodium polycarboxylate, sodium lignosulphonates, calcium ligno sulphate, Poly aryl phenyl ether phosphate, Methyl naphthalene sulfonic acid, polymer with formaldehyde , sodium salt, Tristyrylphenol Ethoxylate Amine salt of phosphate, tristyryl phenol ethylate, Acrylic Copolymer, Ethoxylated Tristryl phenol Sulphate, Naphthalene sulfonic acid, sodium salt condensate with formaldehyde, Ethoxylated oleyl cetyl alcohol, Polyalkelene glycol, naphthalene sulphonate formaldehyde condensates, tristyrylphenolethoxylate phosphate, sulfonated aromatic polymer, sodium salt, ethoxylated fatty alcohol, alkyl ethoxylates, polymeric dispersant, acrylic graft copolymer, polyalkoxy ethers, EO-PO block copolymers, and graft copolymers, or mixtures thereof and present in the range of 0.1 -20% by weight of the composition.

6. The stable synergistic insecticidal composition as claimed in claim 4, wherein the emulsifiers are selected from the group comprising ionic emulsifier, non-ionic emulsifier or Castor oil or its ethoxylates, tall oil or its ethoxylates, Calcium alkyl benzene sulfonate, polymeric dispersant or mixtures thereof and present in the range of 0.1-15% by weight of the composition.

7. The stable synergistic insecticidal composition as claimed in claim 4, wherein the anti-freezing agent is selected from the group comprising glycols, monoethylene glycol, diethylene glycol, polyethylene glycols, methoxypolyethylene glycols, propylene glycol, polypropylene glycols, polybutylene glycols, glycerine, ethylene glycol and mixtures thereof and present in the range of 0.1-20% by weight of the composition.

8. The stable synergistic insecticidal composition as claimed in claim 4, wherein the antifoaming agent is selected form the group comprising silicon emulsion based anti-foam agents, Siloxane poly alkyleneoxide, trisiloxane ethoxylates, Polydimethylsiloxane emulsion and mixtures thereof and present in the range of 0.1-10% by weight of the composition.

9. The stable synergistic insecticidal composition as claimed in claim 4, wherein the wetting agent is selected form the group comprising Sodium salt of sulphated product, sodium lauryl sulphate, sodium dioctylsulphosuccinate, Tristyrylphenolethoxylate non-ionic emulsifier, mixture of nonionic surfactants & Alkoxylated Alcohol, Block copolymer, alkyl phenol ethoxylates, and aliphatic alcohol ethoxylates, their salts and mixtures thereof and present in the range of 0.1-10% by weight of the composition.

11. The stable synergistic insecticidal composition as claimed in claim 4, wherein the antimicrobial / anti-bacterial agent is selected from the group comprising propionic acid and its sodium salt; sorbic acid and its sodium or potassium salts; benzoic acid and its sodium salt, hydroxy benzoic acid sodium salt, methyl p-hydroxy benzoate, and biocide such as sodium benzoate, sodium o-phenyl phenate, l,2-benzisothiazoline-3-one, 2-methyl-4-isothiazolin-3-one, 5-chloro-2-methyl-4-isothiazolin-3-one, potassium sorbate, parahydroxy benzoates, Benzisothiazolin-3-one, Formaldehyde or mixtures thereof and present in the range of 0.01-10% by weight of the composition.

12. The stable synergistic insecticidal composition as claimed in claim 4, wherein the thickening agent is selected from the group comprising montmorillonite, bentonite clay, magnesium aluminium silicate, attapulgite, natural extracts of seeds and seaweeds, guar gum, locust bean gum, carrageenam, xanthan gum, alginates, polysaccharides, methyl cellulose, carboxymethyl cellulose (CMC), hydroxyethyl cellulose (HEC), bentonite clay, modified starches, polyacrylates, polyvinylalcohol and polyethylene oxide or mixtures thereof and present in the range of 0.1-10% by weight of the composition.

13. The stable synergistic insecticidal composition as claimed in claim 4, wherein the filler is selected from the group comprising Silicon Dioxide, bentonite clay, china clay, precipitated silica, kaolin, talcum powder, starch, urea formaldehyde resin and diatomaceous earth, lactose monohydrate and mixtures thereof and present in the range of 0.1-90% by weight of the composition.

14. The stable synergistic insecticidal composition as claimed in claim 4, wherein the adjuvants are selected from the group comprising Silicone Ethoxylated Oil, Polyvinyl Pyrrolidone, Polyvinyl Alcohol or mixtures thereof and present in the range of 0.1-10% by weight of the composition.

15. The stable synergistic insecticidal composition as claimed in claim 4, wherein the solvents and cosolvents are selected from the group comprising heavy aromatic hydrocarbon, N-methyl pyrollidone(NMP), Di-methyl sulfoxide(DMSO), N- alcohol, alkyl amide, vegetable oil, mineral oil, aromatic solvents, solvent naptha (solvent C-IX) , water or mixtures thereof and present in the range of 0.1-90% by weight of the composition.

16. The stable synergistic insecticidal composition as claimed in claim 1 , wherein the composition is formulated as Micro-emulsion (ME), Capsule suspension (CS), Dispersible concentrate (DC), Dustable powder (DP), Powder for dry seed treatment (DS), Emulsifiable concentrate (EC), Emulsifiable granule (EG), Emulsion water-in-oil (EO), Emulsifiable powder (EP), Emulsion for seed treatment (ES), Emulsion oil-in-water (EW), Flowable concentrate for seed treatment (FS), Granules (GR), Micro-emulsion (ME), Oil-dispersion (OD), Oil 20 miscible flowable concentrate (OF), Oil miscible liquid (OL), Oil dispersible powder (OP), Suspension concentrate (SC), Suspension concentrate for direct application (SD), Suspo-emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Spreading oil (SO), Water soluble powder (SP), Water soluble tablet (ST), Ultra-low volume (ULV) suspension, Tablet (TB), Ultra-low volume (ULV) liquid,Water dispersible granules (WG), Wettable powder (WP), Water dispersible powder for slurry seed treatment (WS), Water dispersible tablet (WT), a mixed formulation of CS and SC (ZC) or a mixed formulation of CS and SE (ZE) and a mixed formulation of CS and EW (ZW).

17. The stable synergistic water dispersible granule insecticidal composition comprising: a) Compound of Formula I i.e. 3-mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3,3- dimethylbutyrate or its agrochemically acceptable salts, esters and derivatives, in the range of 0.1 to 85% by weight of the composition; b) Emamectin Benzoate, in the range of 0.1 to 85% by weight of the composition; and c) Compound of Formula II i.e.3-iodo-A'-(2-mesyl-l,l-dimethylethyl)-A-{4-[l,2,2,2- tetrafluoro-l(trifluoromethyl)ethyl]-c>-tolyl} phthalamide or its agrochemically acceptable salts, esters and derivatives, in the range of 0.1 to 85% by weight of the composition.

18. The stable synergistic Suspension concentrate composition comprising: a) Compound of Formula I i.e. 3-mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3,3- dimethylbutyrate or its agrochemically acceptable salts, esters and derivatives, in the range of 0.1 to 85% by weight of the composition; b) Emamectin Benzoate, in the range of 0.1 to 85% by weight of the composition; and c) Compound of Formula II i.e.3-iodo-A'-(2-mesyl-l,l-dimethylethyl)-A-{4-[l,2,2,2- tetrafluoro-l(trifluoromethyl)ethyl]-c>-tolyl} phthalamide or its agrochemically acceptable salts, esters and derivatives, in the range of 0.1 to 85% by weight of the composition.

19. The stable synergistic insecticidal composition as claimed in claim 17 and 18 further comprising one or more agrochemically acceptable excipients.

20. A kit-of-parts comprising a plurality of components as claimed in claim 1 , wherein said plurality of components comprises: a) Compound of Formula I i.e. 3-mesityl-2-oxo-l-oxaspiro[4.4]non-3-en-4-yl 3,3- dimethylbutyrate or its agrochemically acceptable salts, esters and derivatives; b) Emamectin or its agrochemically acceptable salts, esters and derivatives; c) Compound of Formula II i.e. 3-iodo-A'-(2-mesyl-l,l-dimethylethyl)-A-{4-[ 1 ,2,2,2-tetrafluoro- 1 (trifluoromethyl)ethyl] -o-tolyl } phthal amide or its agrochemically acceptable salts, esters and derivatives.

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