Burn and scald tincture and preparation method therefor

By using a burn and scald tincture containing a variety of natural Chinese herbal medicines, the existing treatment methods are solved, which are slow to be effective, easily infected and scar-free, and the effect of quickly eliminating pain and redness, preventing infection and promoting healing is achieved.

WO2025065255A1PCT designated stage expired Publication Date: 2025-04-03HUA SHAN
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Patent Information

Application Number
PCT/CN2023/121615
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Filing Date
2023-09-26
Publication Date
2025-04-03

AI Technical Summary

Technical Problem

The existing traditional Chinese medicine compositions for treating burns and scalds have slow effect, long treatment course, poor effect, easy to get infected and suppurate, and may leave scars.

Method used

A burn and scald tincture is used, including honeysuckle, Liu Jinu, cypress, coptis chinensis, rhubarb, scutellaria baicalensis, cabbage, frankincense, myrrh, borneol and 80% ethanol. The active ingredients of the drug are extracted through soaking and diafiltration to form a non-irritating and non-toxic side effects tincture, which is used to quickly eliminate the pain and swelling caused by burns and scalds, and prevent infection and scar formation.

Benefits of technology

This tincture can quickly eliminate the pain and redness caused by burns and scalds, prevent the burns and scalds from expanding and infection and suppuration, and promote the rapid healing of burns and scalds without leaving scars.

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Abstract

A burn and scald tincture and a preparation method therefor. The burn and scald tincture comprises the following raw material components: honeysuckle, siphonostegia, arnebia root, rhizome of Chinese goldthread, root and rhizome of sorrel rhubarb, phellodendron bark, root of baikal skullcap, black catechu, frankincense, myrrh, borneol, and 80% ethanol. The preparation method comprises: 1) weighing raw material components on the basis of a weight part ratio; 2) drying and grinding honeysuckle, arnebia root, siphonostegia, rhizome of Chinese goldthread, root of baikal skullcap, phellodendron bark, root and rhizome of sorrel rhubarb, frankincense, and myrrh into coarse powder, and drying and grinding black catechu into fine powder; 3) soaking the ground medicinal materials in 80% ethanol and sealing same; 4) collecting a percolate, and adding 80% ethanol to dregs for soaking, filtering, and dregs squeezing; 5) collecting a filtrate, combining same, and adding borneol and water for injection; and 6) filtering and aliquoting the resulting product into brown sealed glass bottles or small sprayers. According to the tincture for treating burns and scalds, appropriate pure natural Chinese medicinal materials are selected to cooperate with one another and act synergistically, the preparation method is simple and easy to operate, and the tincture has significant efficacy, is easy to use, and has less side effects and low costs.
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Description

Burn and scald tincture and preparation method thereof Technical Field

[0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a burn and scald tincture and a preparation method thereof. Background Art

[0002] Burns primarily refer to damage to the skin, mucous membranes, and even deeper tissues caused by heat, chemicals, electricity, radiation, and other factors. Skin burns caused by thermal factors (such as flames or boiling water) are the most common. According to statistics, burns are the second leading cause of death from accidental injuries each year, second only to traffic accidents. Furthermore, a significant number of traffic accident victims also suffer from burns.

[0003] The severity of a burn depends on the extent and depth of the injured tissue. Burn depth is categorized as first-degree, second-degree, or third-degree. First-degree burns are the least damaging, with the burned skin appearing red, painful, and tender, with exudate or edema. The affected area may blanch with light pressure, but no blisters may form. Second-degree burns are deeper, with blisters forming at the base of the skin. These blisters are red or white, filled with a clear, viscous fluid, are tender to the touch, and blanch with pressure. Third-degree burns are the deepest, with the surface appearing whitish, soft, or black, resembling charred leather. Because the burned skin appears pale, it can often be mistaken for normal skin in fair-skinned individuals, but it no longer changes color when pressed. Destroyed red blood cells can cause the burned area to appear bright red. Blisters may occasionally form, and hair in the burned area can be easily pulled out, resulting in decreased sensation. Third-degree burns generally do not cause pain because nerve endings in the skin are destroyed. It often takes several days after the burn to distinguish between deep second-degree and third-degree burns.

[0004] Burns are common in everyday life, primarily caused by contact between boiling water, boiling oil, motorcycle exhaust pipes, and ultraviolet rays from the sun, leading to localized skin and tissue damage, resulting in a range of clinical symptoms, including functional impairment, pain, and localized necrosis. These injuries are often accompanied by flushing and edema, with significant fluid exudation. Symptoms include redness, swelling, burning pain, blistering, and eschar formation. Mild burns can damage the skin and fur, or even the muscles and tendons. Severe burns can result in intense fire poisoning, depleting body fluids, allowing pathogenic toxins to invade the blood and attack the internal organs, causing various symptoms. Clinically, burns are categorized into three degrees: First-degree burns: These only damage the surface layer of the skin, resulting in mild localized redness and swelling, no blisters, and significant pain. Second-degree burns: These damage the dermis, resulting in localized redness, swelling, pain, and blisters of varying sizes. Third-degree burns: These damage the subcutaneous layer, damaging fat, muscle, and bone, and appearing gray or reddish-brown. For extensive burns, seek medical treatment promptly.

[0005] According to Traditional Chinese Medicine, burns and scalds are caused by the invasion of fire, heat and toxic evil into the body, which leads to damage to the skin surface, blocked blood vessels, flesh rot caused by excessive heat, incomplete skin surface, loss of body fluids, and loss of body yin fluids. Clinical symptoms such as local redness, swelling, blisters, and sores may occur. Therefore, topical medications are mainly used to clear away heat and toxins, promote blood circulation and remove blood stasis, and astringe and relieve pain.

[0006] Burns and scalds are treated with four major challenges: wound surface pain, progressive necrosis, susceptibility to infection, and scar healing. Consequently, there is an urgent need to find more effective therapeutic agents. In daily life, skin burns or scalds caused by careless behavior often occur, ranging from pain and redness in mild cases to blistering and even exfoliation and necrosis in severe cases, with injuries to bones. If left untreated, pathogens and bacteria can invade, enlarging the wound surface and causing skin ulceration, and even infection, sepsis, and death. While Western medicines offer the advantages of rapid and definite efficacy, they are irritating to the human body and can, to a certain extent, develop drug resistance and side effects. While some Chinese herbal compositions for treating burns and scalds exist in the prior art, these compositions all present the following problems: slow onset of action, long treatment courses, poor efficacy, inability to heal naturally, and even infection and suppuration, which can easily leave scars. Therefore, a burn and scald tincture and its preparation method have become urgent issues to be addressed.

[0007] Summary of the Invention

[0008] The technical problem to be solved by the present invention is to provide a Chinese medicine tincture for treating burns and scalds, which is prepared by selecting appropriate pure natural Chinese medicinal materials and their proportions, is non-irritating, has no toxic side effects, is easily accepted by patients, has a high degree of safety, is quick to take effect, has a good effect in treating burns and scalds, can quickly eliminate the pain, redness and swelling and other complications caused by burns and scalds, prevents the burns and scalds from expanding, becoming infected and suppurating, promotes the burns and scalds to heal quickly, and does not leave scars, and a preparation method thereof.

[0009] In order to solve the above technical problems, the technical solution provided by the present invention is a burn and scald tincture, which comprises the following components in parts by weight: 100-500 parts of honeysuckle, 150-450 parts of lily of the valley, 150-500 parts of lithospermum officinale, 200-400 parts of coptis chinensis, 250-700 parts of rhubarb, 600-1000 parts of phellodendron amurense, 500-900 parts of scutellaria baicalensis, 200-700 parts of catechu, 250-650 parts of frankincense, 300-700 parts of myrrh, 300-800 parts of borneol, and 5000-15000 ml of 80% ethanol.

[0010] As an improvement, the invention comprises the following components in parts by weight: 200-400 parts of honeysuckle, 200-300 parts of Liujienu, 150-300 parts of Lithospermum erythrorhizon, 300-400 parts of Coptis chinensis, 400-600 parts of Rhubarb, 700-900 parts of Phellodendron chinense, 700-900 parts of Scutellaria baicalensis, 400-600 parts of catechu, 300-600 parts of frankincense, 400-550 parts of myrrh, 400-700 parts of borneol, and 8000-12000 ml of 80% ethanol.

[0011] As an improvement, the invention includes the following components in parts by weight: 300 parts of honeysuckle, 300 parts of Liujienu, 300 parts of Lithospermum erythrorhizon, 300 parts of Coptis chinensis, 500 parts of Rhubarb, 800 parts of Phellodendron amurense, 800 parts of Scutellaria baicalensis, 500 parts of catechu, 500 parts of frankincense, 500 parts of myrrh, 500 parts of borneol, and 10,000 ml of 80% ethanol.

[0012] A method for preparing a burn and scald tincture comprises the following steps:

[0013] 1) Weigh each component according to its weight ratio;

[0014] 2) Dry honeysuckle, lithospermum officinale, lily of the valley, coptis chinensis, scutellaria baicalensis, phellodendron amurense, rhubarb, frankincense, and myrrh, mix them according to proportion, crush them, and grind them into coarse powder; dry catechu and grind it into fine powder;

[0015] 3) Soak the ground drug in 80% ethanol and seal for 7-10 days;

[0016] 4) Collect the leachate residue and add 80% ethanol to soak for 5-7 days, then leachate and press the residue;

[0017] 5) Collect the filtrate twice, combine it, add borneol and water for injection, and soak and dissolve;

[0018] 6) filtering through 40 mesh and packaging in sealed brown glass bottles or small sprayers for later use to obtain the medicinal tincture for treating burns and scalds of the present invention.

[0019] As an improvement, in step 2, after the medicine is ground, the coarse powder is passed through a 50-mesh sieve, and the fine powder is passed through a 100-mesh sieve.

[0020] As an improvement, in the dissolution process in step 5, the ethanol content of the extract needs to be checked with an alcohol meter, and then diluted to between 72% and 75% by adding sterile water for injection.

[0021] As an improvement, in step 3, the mixture is shaken or stirred once a day during the soaking process.

[0022] The sources and functions of the various medicinal materials used in the formula of the present invention are as follows:

[0023] The following three medicines are the main ones:

[0024] Honeysuckle is a semi-evergreen, twining vine with a sweet taste and cold properties. It is used to treat carbuncles, furuncles, sore throat, erysipelas, dysentery caused by heat toxins, colds, and fevers due to febrile diseases. It contains chlorogenic acid and inositol. It has heat-clearing and detoxifying properties, as well as antibacterial and antimicrobial properties, including bactericidal and antibacterial effects against various pathogens, including Pseudomonas aeruginosa, hemolytic Streptococcus, and Staphylococcus aureus.

[0025] Liu Jinu is a plant of the genus Artemisia in the Asteraceae family. It is bitter in taste and warm in nature. It has the effects of promoting blood circulation and removing blood stasis, relieving menstruation and pain, cooling blood and stopping bleeding, clearing heat and removing dampness.

[0026] Lithospermum is sweet and cold in nature. It has the effects of clearing heat and cooling blood, promoting blood circulation and detoxifying, and removing rashes and spots. Lithospermum contains acetylshikonin, which can reduce the permeability of capillaries in inflamed wounds, reduce fluid exudation, and make necrotic skin form dense protein, promoting rapid growth and healing of epithelial tissue without leaving scars.

[0027] The following four medicines are ministerial medicines:

[0028] Coptis chinensis is a perennial herbaceous plant in the Ranunculaceae family and the genus Coptis. It has a bitter taste and is known for clearing heat, drying dampness, purging fire, and detoxifying. It is used to treat damp-heat-induced fullness, vomiting, acid regurgitation, diarrhea, jaundice, high fever and coma, hyperactive heart fire, restlessness and insomnia, vomiting and bleeding due to blood heat, conjunctivitis, toothache, diabetes, carbuncles, and furuncles. It is also used externally to treat eczema, eczema, and auricular discharge. Coptis chinensis prepared with wine is effective in clearing heat from the upper burner and is used for conjunctivitis and mouth sores. Modern pharmacological research has demonstrated that Coptis chinensis possesses broad-spectrum antibacterial properties, particularly against Staphylococcus aureus and hemolytic Streptococci.

[0029] Scutellaria baicalensis, a plant of the genus Scutellaria in the Lamiaceae family, is bitter in flavor and cold in nature. It has the effects of clearing heat and purging fire, drying dampness, detoxifying, and stopping bleeding. It is mainly used to treat febrile diseases, upper respiratory tract infections, lung heat cough, damp-heat jaundice, pneumonia, dysentery, hemoptysis, conjunctivitis, fetal restlessness, hypertension, carbuncles, furuncles, and boils.

[0030] Phellodendron amurense is the dried bark of the Phellodendron chinense tree, also known as Phellodendron chinense, in the Rutaceae family. It has a bitter taste and cold properties, and is known to clear heat and dampness, purge fire and detoxify, and has astringent and antipruritic properties. It is primarily used to treat inflammatory conditions such as acute bacterial dysentery, acute enteritis, acute icteric hepatitis, and urinary tract infections. It can also be used externally to treat burns, otitis media, and acute conjunctivitis.

[0031] Rhubarb, the dried root and rhizome of Rheum palmatum, Rheum tanguticum, or Rheum officinale, all from the Polygonaceae family, is bitter in flavor and cold in nature. It has the effects of clearing heat, purging fire, cooling blood, and detoxifying, purging accumulations, and promoting blood circulation and removing blood stasis. The combination of these four herbs enhances their heat-clearing and detoxifying, astringent, and dampness-drying properties, helping to alleviate symptoms such as hematemesis, epistaxis, hemoptysis, sore throat, swollen and painful gums, and red and swollen eyes caused by blood heat. The anthraquinone compounds in rhubarb promote platelet production, shorten clotting time, and facilitate hemostasis. It has strong anti-infective and analgesic properties, and is effective against a variety of Gram-positive and Gram-negative bacteria, particularly those sensitive to Staphylococci and Streptococci.

[0032] The following two drugs are adjuvants, which are often used together to enhance their effects of reducing swelling and relieving pain, promoting blood circulation and removing blood stasis:

[0033] Frankincense is a resin exuded from the bark of the Oleaceae plant, Boswellia serrata, and related plants. It has a bitter and warm taste and is known to reduce swelling, relieve pain, and promote tissue regeneration. It is used to treat chest pain, heartache, epigastric pain, dysmenorrhea, amenorrhea, postpartum blood stasis, abdominal pain due to abdominal masses, rheumatic pain, muscle spasms, traumatic injuries, and carbuncles and ulcers.

[0034] Myrrh is the dried resin of the Oleaceae plant or Harding tree. It tastes bitter and flat, and has the effects of reducing swelling, promoting tissue regeneration, promoting blood circulation, removing blood stasis and relieving pain. It is mainly used to treat injuries from falls, wounds, pain in the muscles and bones, heart and abdomen, masses, amenorrhea, swelling and pain in carbuncles, and ulcers that do not heal for a long time.

[0035] The following two drugs are adjuvant drugs:

[0036] Catechu is a plant of the leguminous family. It is cold in nature and bitter in taste. It has the effects of promoting blood circulation and relieving pain, stopping bleeding and promoting tissue regeneration, and absorbing dampness and healing sores. It belongs to the category of blood-stasis-removing and hemostatic drugs under the hemostatic category.

[0037] Borneol is a crystallized product derived from the resin and volatile oil of the Dipterocarpaceae plant. It has a bitter, slightly cold aroma and is known to relieve pain, preserve nutrients, clear away heat, and promote tissue regeneration. It also promotes wound healing by increasing granulation tissue structure and epidermal cell regeneration, repairing skin appendages, and improving wound healing.

[0038] In this recipe, 80% ethanol is used as the solvent, which can fully dissolve and extract the active ingredients of the drug through soaking. The most commonly used medical ethanol in clinical practice is 75%, which is usually used for epidermal disinfection. This is because ethanol with too high a concentration forms a protective film on the surface of bacteria, preventing them from entering the body and making it difficult to completely kill bacteria. If the concentration is too low, although it can enter the bacteria, it cannot completely coagulate the proteins in the body. Therefore, using 72%-75% ethanol is the most effective disinfectant and bactericidal, and can also promote blood circulation in the skin wound, assisting the disinfection and bactericidal effect of the drug.

[0039] The whole formula complements each other, the combination is rigorous, and the medication is appropriate, so it can be effective.

[0040] The advantages of the present invention compared with the prior art are:

[0041] 1) The burn and scald tincture of the present invention has the smell of Chinese herbal alcohol. It is prepared according to a secret recipe passed down from generation to generation, with the selection of appropriate pure natural Chinese medicinal materials and their proportions. The components cooperate with each other and act synergistically. The preparation method strives to be simple and easy to operate, and the freshness of the medicine is kept to the maximum extent. Raw herbs are used as much as possible. Stir-fried and steamed herbs are not as good as raw herbs. For external treatment, raw herbs have the best therapeutic effect.

[0042] 2) The burn and scald tincture of the present invention is non-irritating, has no toxic side effects, is easily accepted by patients, has a high degree of safety, and is quick to take effect. It has a good effect in treating burns and scalds, can quickly eliminate complications such as pain and redness and swelling caused by burns and scalds, and prevents the burn and scald surface from expanding, becoming infected and suppurating, and promotes rapid healing of the burn and scald surface;

[0043] 3) The present invention is mainly used to treat various body surface burns, skin ulcers, impetigo, ulcers, wound infections, athlete's foot infections, etc. The tincture for treating burns and scalds of the present invention is low in cost and effective, and is a medicament suitable for broad-spectrum medical and household use to treat burns and scalds. At the same time, the tincture for treating burns and scalds provided by the present invention is easy to prepare, use and carry, and has a significant therapeutic effect on burns and scald symptoms. DETAILED DESCRIPTION

[0044] The following is a clear and complete description of the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0045] Example 1, the present invention treats burns and scalds medicinal tincture, comprising the following components by weight: 100 grams of honeysuckle, 150 grams of Liu Ji Nu, 150 grams of Lithospermum erythrorhizon, 200 grams of Coptidis, 250 grams of Rhubarb, 600 grams of Phellodendron, 500 grams of Scutellaria baicalensis, 200 grams of catechu, 250 grams of frankincense, 300 grams of myrrh, 300 grams of borneol, and 5000 ml of 80% ethanol.

[0046] Example 2, the present invention treats burns and scalds tincture, comprising the following components by weight: 500 grams of honeysuckle, 450 grams of Liu Ji Nu, 500 grams of Lithospermum erythrorhizon, 400 grams of Coptidis, 700 grams of Rhubarb, 1000 grams of Phellodendron, 900 grams of Scutellaria baicalensis, 700 grams of catechu, 650 grams of frankincense, 700 grams of myrrh, 800 grams of borneol, and 12000 ml of 80% ethanol.

[0047] Example 3, 300 grams of honeysuckle, 300 grams of Liu Ji Nu, 300 grams of Lithospermum erythrorhizon, 300 grams of Coptidis, 500 grams of Rhubarb, 800 grams of Phellodendron chinense, 800 grams of Scutellaria baicalensis, 500 grams of catechu, 500 grams of frankincense, 500 grams of myrrh, 500 grams of borneol, and 10,000 ml of 80% ethanol.

[0048] The preparation method of the medicinal tincture for treating burns and scalds of the present invention comprises the following steps:

[0049] 1) Weigh each component according to its weight ratio;

[0050] 2) Dry honeysuckle, lithospermum officinale, lily of the valley, coptis chinensis, scutellaria baicalensis, phellodendron amurense, rhubarb, frankincense, and myrrh, mix them according to proportion, crush them, grind them into a coarse powder, and pass through a 50-mesh sieve; dry catechu, grind it into a fine powder, and pass through a 100-mesh sieve;

[0051] 3) Soak the ground drug in 7000 ml of 80% ethanol, seal the container, and shake or stir once daily for 10 days. After 7 to 10 days, collect the percolation liquid.

[0052] 4) Add 3000 ml of 80% ethanol to the residue and soak for 7 days. After soaking, squeeze out all the residue and combine the two filtered solutions.

[0053] 5) Add borneol to the soaking mixture to dissolve;

[0054] 6) Check the ethanol content of the extract with an alcohol meter, then dilute it to between 72% and 75% with sterile water for injection. Let it stand, filter it through a 40-mesh filter, and dispense it into sealed brown glass bottles or small sprayers for later use.

[0055] The method for using the burn and scald treating tincture is as follows: when using, the tincture is sprayed on the corresponding part of the patient's wound with a small sprayer.

[0056] Product properties

[0057] This product is a brown or tan translucent liquid with a special odor of alcohol and borneol.

[0058] Functions and indications

[0059] It has antibacterial, anti-inflammatory, blood-activating, muscle-regenerating, astringent, and analgesic properties. It is primarily used for burns and scalds of varying depths and sizes. It can be used for various skin ulcers, impetigo, bedsores (pressure sores), external wound infections, and athlete's foot infections.

[0060] usage

[0061] First, clean the burn wound with 0.1% Sanitary Ware solution or other disinfectant to remove contaminants. Cut off any large blisters and loose scabs, and dry them thoroughly. Use a sprayer or cotton balls to apply the burn tincture to the entire wound. The wound should be fully exposed. For severe cases, spray once or twice an hour. Once a dry scab forms, spray every two to four hours.

[0062] Note: ① Do not bandage the wound surface when using this medicine, and use exposure therapy until it heals; ② Do not put pressure on the wound surface during the application; ③ Because it is ethanol, the pain is obvious when the medicine is first applied, especially for shallow second-degree burns, but it lasts about 10 seconds and is generally well tolerated. If the area is large, a small amount of analgesic and topical anesthetic can be taken before spraying. ④ The injured area should be elevated; ⑤ There will be severe itching during the healing stage, so scratching should be avoided; do not remove the scabs that form, and they should fall off on their own until they heal. (6) This product has no shelf life, and if it is left for a long time and precipitates, it will not affect the therapeutic effect.

[0063] Typical cases:

[0064] Wang Jinyue, a 17-year-old female, suffered first-degree burns on her face, neck, and chest, covering approximately 6% of her body surface area. She was treated with the Chinese herbal burn and scald tincture of the present invention, spraying it six times daily for about a week, using three and a half bottles of 100 ml of the tincture. She recovered after one week, with no scars or pigmentation on the injured areas.

[0065] Li Jinzhi, a 45-year-old female, suffered a second-degree burn on her leg, covering about 3% of her body surface area. She was treated with the Chinese herbal burn tincture of the present invention, spraying it six times daily for about a week, using two and a half bottles of 100 ml of the burn tincture. After a week, the burn was healed without leaving any scars.

[0066] Xiao Weidong, a 29-year-old male, suffered second-degree burns on his head, neck, and back, covering 29% of his body surface area. He was treated with the burn and scald tincture of the present invention, spraying it every two hours for about two weeks, using ten 100ml bottles. He recovered after two weeks. There were no scars or pigmentation on the injuries. See photos for evidence. Mobile phone number: 15589006976.

[0067] Hua Dedong, male, 27 years old. He suffered high-voltage electrical burns on the right side. 1. 0.3% third-degree burn on the right foot, with a visible current exit site at the sole. 2. 1% deep second-degree burn on the right upper limb and shoulder and back. 3. 1% deep second-degree burn on the left upper and lower limb. In addition to Western medication, he used five bottles of 100ml burn tincture from this invention. After two weeks, most of the burns healed, but the current exit site on the sole of the right foot was not completely healed. After one week of continued treatment, the burns healed without scarring or pigmentation. Case history and photos are provided as evidence. Mobile phone number: 15216514998.

[0068] Zhang Jianmei, female, 47 years old. She suffered a crush injury to the foot. She was hospitalized for two months without recovery and was discharged. The wound on the foot was left with no skin, and pus had been oozing for over a year, leaving her unable to walk and developing a chronic ulcer. She was treated with the Chinese herbal burn tincture of this invention, spraying it four times daily for about a year and a half, using a total of 2,500 ml. She is essentially fully recovered. See photos for evidence. Mobile phone number: 15853954780

[0069] Ma Lili, a 6-year-old female, suffered a first-degree burn on her left arm, covering approximately 2% of her body surface area. She was treated with the Chinese herbal burn tincture of the present invention, sprayed five times for one week, using a total of one and a half bottles of 100 ml of the tincture. The wound healed without scarring or pigmentation.

[0070] Guo Jingfu, a 56-year-old male, suffered a second-degree burn on his right lower leg, covering approximately 3% of his body surface area. He was treated with the burn and scald tincture of the present invention, spraying it six times daily. He recovered in 12 days. He used three 100ml bottles of the burn and scald tincture, and the affected area healed without scarring or pigmentation.

[0071] Gong Xiangcai, a 53-year-old male, suffered a second-degree burn on the outer front of his left thigh, covering approximately 55% of his body surface area. He was treated with the burn and scald tincture of the present invention, spraying it 6-8 times daily. He recovered in about two weeks. Five 100ml bottles of the tincture were used. He recovered without scarring or pigmentation.

[0072] Wang Xiaodan, a 6-year-old female, suffered second-degree burns on both thighs and buttocks, covering approximately 7% of her body surface area. She was treated with the burn and scald tincture of the present invention, spraying the outer surface 6-8 times daily. She recovered in about 2 weeks. Six 100ml bottles of the burn and scald tincture were used. She recovered without scarring or pigmentation.

[0073] Ma Juan, a 5-year-old female, suffered first-degree burns on her right wrist and face, covering approximately 4% of her body surface area. She was treated with the burn and scald tincture of the present invention, spraying it six times daily. After one week of continuous use, using three 100 ml bottles of the tincture, she recovered completely, with no scars or pigmentation.

[0074] Liu Hongjing, a 49-year-old female, suffered a second-degree burn on her left lower leg, covering approximately 4% of her body surface area. She was treated with the Chinese herbal burn tincture of the present invention, 6-8 times daily for approximately 2 weeks, using four 100ml bottles of the tincture. After 2 weeks, the burn healed without scarring or pigmentation.

[0075] Typical cases of bedsore infection treated with burn and scald medicine

[0076] Case 1: Gao Liying, a 94-year-old female, developed a bedsore (pressure ulcer) covering 3% of her body surface area due to long-term bed rest. Initial treatment with anti-infective drugs was ineffective. She then applied the Chinese herbal burn tincture of the present invention six times daily. After two weeks, the affected area healed, and she used three 100 ml bottles of the tincture, leaving no scars.

[0077] Case 2, Hua Mingqi, male, 67 years old, vegetative state after cerebral hemorrhage, suffering from bedsore (pressure sore) infection. Use the Chinese medicine tincture of the present invention to spray and treat, 6 times a day, the affected part is healed after one week, and a total of 3 bottles of 100 ml of Chinese medicine tincture are used, and no scar is left.

[0078] Case 3, Mi Jinghua, female, 86 years old. Hemiplegia for many years, suffering from bedsore (pressure sore) infection, with the Chinese medicine tincture of the present invention spray treatment, 6 times a day, one week after the affected part healed, a total of 100 ml of 2 bottles of Chinese medicine tincture, no scar left.

[0079] Case 4: Hua Shouli, male, 89 years old. He suffered from hemiplegia for many years. He developed a bedsore (pressure sore) infection and was treated with the Chinese medicine tincture of the present invention, spraying it six times a day. The affected area healed after one week, using two 100 ml bottles of the tincture, and no scars were left.

[0080] Case 5, Lin Chuanjun, male, 76 years old. A vegetative state after cerebral infarction, he suffered from bedsores (pressure sores) and was treated with the Chinese herbal tincture of the present invention, sprayed six times daily. The affected area healed after one week. Two 100 ml bottles of the Chinese herbal tincture of the present invention were used together, leaving no scars.

[0081] Case 6, Zhang Zongli, male, 85 years old. He was in a vegetative state due to cerebral hemorrhage and suffered from a bedsore (pressure sore) infection. He was treated with the Chinese medicine tincture of the present invention sprayed five times a day. The affected area healed after 10 days. A total of three 100 ml bottles of the Chinese medicine tincture were used. No scars were left, but there was a white pigmentation on the skin.

[0082] It should be noted that the ethanol content of the product should be 72% to 75%, the extract should be semi-clear with a small amount of precipitation, and other requirements should comply with the provisions of the tincture in the Chinese Pharmacopoeia.

[0083] The Chinese medicinal raw materials in the above composition can be replaced by appropriate Chinese medicinal materials with the same medicinal properties, and the medicinal effects of the Chinese medicinal preparations after replacement remain unchanged.

[0084] In the above formulas, the weight of the medicine is calculated based on the raw medicine, and the weight ratio is used as the proportion. It can be increased or decreased in proportion during production. For example, large-scale production can be measured in kilograms or tons, and small-scale production can be measured in grams or milligrams. The weight can be increased or decreased, but the weight ratio of the raw medicines in each component remains unchanged.

[0085] It is necessary to point out here that the above embodiments and test examples are limited to further elaboration and understanding of the technical solution of the present invention, and cannot be understood as further limitation of the technical solution of the present invention. Inventions and creations with non-outstanding substantive features and significant progress made by those skilled in the art still fall within the scope of protection of the present invention.

Claims

1. A burn and scald tincture, characterized in that: The invention comprises the following components in parts by weight: 100-500 parts of honeysuckle, 150-450 parts of lily of the valley, 150-500 parts of lithospermum, 200-400 parts of coptis root, 250-700 parts of rhubarb, 600-1000 parts of phellodendron, 500-900 parts of scutellaria, 200-700 parts of catechu, 250-650 parts of frankincense, 300-700 parts of myrrh, 300-800 parts of borneol and 5000-15000ml of 80% ethanol.

2. A burn and scald tincture according to claim 1, comprising the following components in parts by weight: 200-400 parts of honeysuckle, 200-300 parts of Achyranthes bidentata, 150-300 parts of Lithospermum officinale, 300-400 parts of Coptidis rhizome, 400-600 parts of Rhubarb, 700-900 parts of Phellodendron chinense, 700-900 parts of Scutellaria baicalensis, 400-600 parts of catechu, 300-600 parts of frankincense, 400-550 parts of myrrh, 400-700 parts of borneol, and 80% ethanol 8000-12000ml.

3. A burn and scald tincture according to claim 2, characterized in that: 300 parts of honeysuckle, 300 parts of Liu Ji Nu, 300 parts of lithospermum, 300 parts of coptis, 500 parts of rhubarb, 800 parts of phellodendron, 800 parts of scutellaria, 500 parts of catechu, 500 parts of frankincense, 500 parts of myrrh, 500 parts of borneol, and 10000ml of 80% ethanol.

4. A method for preparing a burn and scald tincture, characterized in that: The steps include: 1) Weigh each component according to its weight ratio; 2) After drying, honeysuckle, lithospermum officinale, rhizoma scutellariae, rhubarb, frankincense and myrrh are mixed, crushed and ground into coarse powder according to proportion; after drying, catechu is ground into fine powder; 3) Soak the ground medicine in 80% ethanol and seal for 7-10 days; 4) collecting the leachate residue and then adding 80% ethanol to soak for 5-7 days, then leachate and press the residue; 5) collecting the filtrate twice, combining it, adding borneol and water for injection, soaking and dissolving; 6) Filter through 40 mesh and pack into airtight brown glass bottles or small sprayers for standby use to obtain the medicinal tincture for treating burns and scalds of the present invention.

5. The method for preparing a burn and scald tincture according to claim 4, wherein: In the step 2, after the drug is ground, the coarse powder is passed through a 50-mesh sieve, and the fine powder is passed through a 100-mesh sieve.

6. The method for preparing a burn and scald tincture according to claim 4, wherein: During the dissolution process in step 5, the ethanol content of the extract needs to be checked with an alcohol meter, and then sterile water for injection is added to dilute it to between 72% and 75%.

7. The method for preparing a burn and scald tincture according to claim 4, wherein: In step 3, the mixture is shaken or stirred once a day during the soaking process.

Citation Information

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