Plant disease control composition and plant disease control method

Abstract

The present disclosure provides a plant disease control composition that exhibits a superior control effect on plant diseases as compared with a plant disease control composition containing tebufloquin as a sole active ingredient. The plant disease control composition comprises tebufloquin and a respiratory inhibitor.

Description

Plant disease control composition and plant disease control method

[0001] The present disclosure relates to a plant disease control composition and a plant disease control method.

[0002] Pesticides are used in agricultural production to control pests and weeds in agricultural crops, reduce agricultural labor, and stabilize the quality and yield of agricultural products, and are therefore essential to agriculture for ensuring agricultural production. Pesticides include, for example, herbicides, insecticides, fungicides, and plant growth regulators. Furthermore, fungicides, i.e., plant disease control agents, are used for the purpose of disease control, but frequent and excessive use of fungicides with the same action against specific plant diseases has become a problem in that plant pathogens become resistant to the fungicides.

[0003] Respiratory inhibitors include inhibitors of Complex I, Complex II, and Complex III in the mitochondrial electron transport chain, uncoupling inhibitors of oxidative phosphorylation, ATP synthase inhibitors, and inhibitors related to ATP transport, and are widely used as fungicides (e.g., Non-Patent Document 1).

[0004] Complex II inhibitors include SDHI (Succinate dehydrogenase inhibitors), and Complex III inhibitors include QoI (Quinone outside inhibitors), QiI (Quinone inside inhibitors), and QoSI (Quinone outside inhibitor, stigmatellin binding type). While these inhibitors are highly effective against many diseases, the emergence of resistant bacteria has become a problem (e.g., Non-Patent Documents 1 and 2).

[0005] QoI agents are also known as strobilurin fungicides, or methoxyacrylate fungicides due to their characteristic structure. Methoxyacrylate fungicides are specifically classified into methoxyacrylate, oxyiminoacetamide, methoxycarbamate, oxyiminoacetate, methoxyacetamide, dihydrodioxazine, and benzylcarbamate structures based on structural similarity (Non-Patent Document 1). QoI agents exhibit fungicidal activity as respiratory inhibitors by binding to the ubiquinone-binding QoI site of the mitochondrial cytochrome bc1 complex (Complex III), causing respiratory inhibition. QoI agents have been widely used and selected as core agents, resulting in the identification of resistant bacteria. It has been revealed that the main mutation sites are a substitution of glycine at position 143 of cytochrome b to alanine (referred to as G143A, hereinafter), F129L, G137R, etc. (Non-Patent Documents 1 and 2). On the other hand, QoI agent-resistant soybean rust fungi mainly have the F129L mutation in cytochrome b, and the activity of methoxyacrylate fungicides such as azoxystrobin, dimoxystrobin, metominostrobin, fluoxastrobin, and kresoxymethyl, which are used to control soybean rust, is reduced to a level that is problematic for practical use (Non-Patent Document 3). On the other hand, bifemetostrobin and various compounds with a methoxyacrylate skeleton have been found as next-generation QoI fungicides that do not exhibit cross-resistance with F129L and target QoI agent-resistant soybean rust fungicides caused by the F129L mutation (Non-Patent Document 4, Patent Documents 1 to 8).

[0006] Fungicidal compounds including tebufloquine have been shown to be effective as agents for controlling plant diseases such as rice blast (for example, Patent Documents 9 and 10). In particular, tebufloquine is a fungicide that is effective against diseases such as rice blast (Pyricularia oryzae), soybean purple spot (Cercospora kikuchii), onion rust (Puccinia allii), onion black spot (Alternaria porri), Chinese cabbage black spot (Alternaria brassicicola), tomato powdery mildew (Lycopersicon esculentum), tea ring spot (Pestalothiopsis longiseta), and tea shoot wither (Pestalothiopsis longiseta) (e.g., Non-Patent Document 5). Its activity is said to be derived from its respiratory inhibitor properties, but since it does not show cross-resistance with existing Qol agents, it is presumed that its mode of action is different from that of existing respiratory inhibitors (e.g., Non-Patent Document 6).

[0007] It has been shown that a composition containing tebufloquine and a diamine derivative having an oxycarbonyl group with a halogen-substituted hydrocarbon is active against plant diseases including rice blast (e.g., Patent Document 11). It has also been shown that a composition containing an amide compound and tebufloquine is active against Botrytis cinerea (e.g., Patent Document 12). Furthermore, it has been shown that a composition containing tebufloquine and a fungicidal compound is active against rice blast and cucumber powdery mildew (e.g., Patent Document 13).

[0008] On the other hand, the combined use of tebufloquine and QoI agents has been limited to rice blast fungus and other diseases, and its effectiveness against other diseases has not been clarified. Furthermore, cases of combined use of tebufloquine with respiratory inhibitors such as SDHI agents, and the control and synergistic effects of the combined use against various diseases have not been clarified.

[0009] International Publication No. 2021 / 153782 International Publication No. 2021 / 153794 International Publication No. 2022 / 004702 International Publication No. 2022 / 004704 International Publication No. 2021 / 176007 International Publication No. 2021 / 176057 International Publication No. 2021 / 226234 International Publication No. 2021 / 053136 JP 2003-55114 A Publication No. International Publication No. 2004 / 039156 International Publication No. 2006 / 106811 JP 2011-201858 A Publication No. 2007-112760 A

[0010] FRAC (FUNGICIDE RESISTANCE ACTION COMMITTEE) URL: https: / / www.frac.info / Hideo Ishii, "Current Status of QoI and SDHI Resistant Bacteria and Drug Usage Guidelines," Plant Protection, No. 69, pp. 469-474, August 2015. Pesq. Agropec. Bras (Brasilia), Vol. 51, No. 5, pp. 07-421, 2016. BCPC. Compendium of Pesticide Common Names, Index of New ISO Common Names. https: / / pesticidecompendium.bcpc.org / index_new_frame.html Development of the fungicide tebufloquine, Monthly Fine Chemical, Vol. 44, pp. 17-22, 2015. Action characteristics and susceptibility testing of the new fungicide tebufloquine (Tri (registered trademark)), Abstracts of the 22nd Fungicide Resistance Research Meeting, pp. 29-38, 2012.

[0011] In light of the above situation, a technology for controlling plant diseases by mixing fungicides with different modes of action is desired as a measure to prevent the emergence of further resistant bacteria.

[0012] The problem to be solved by one embodiment of the present disclosure is to provide a plant disease control composition that exhibits superior plant disease control effect compared to a plant disease control composition containing tebufloquine alone as an active ingredient. The problem to be solved by another embodiment of the present disclosure is to provide a plant disease control method using the plant disease control composition.

[0013] Means for solving the above problems include the following aspects: <1> A plant disease control composition comprising tebufloquine and a respiratory inhibitor. <2> The plant disease control composition according to <1>, wherein the respiratory inhibitor is one or more selected from the group consisting of mitochondrial electron transport complex I (Complex I) inhibitors, mitochondrial electron transport complex II (Complex II) inhibitors, mitochondrial electron transport complex III (Complex III) inhibitors, oxidative phosphorylation uncoupling inhibitors, ATP synthase inhibitors, and ATP transport inhibitors. <3> The mitochondrial electron transport complex I (Complex I) inhibitor is one or more selected from the group consisting of diflumetrim, tolfenpyrad, and fenazaquin, Mitochondrial electron transport chain complex II (Complex II) inhibitors include penthiopyrad, fluxapyroxad, penflufen, furametpyr, bixafen, benzovindiflupyr, isopyrazam, sedaxane, fluindapyr, inpyrfluxam, thifluzamide, isofetamide, fluopyram, pyrazid, one or more selected from the group consisting of flumid, isoflucipram, cyclobutrifluram, boscalid, oxycarboxin, carboxin, fenfuram, pydiflumetofen, benodanil, mepronil, flutolanil, pyrapropoyne, fenopyramide, and flubeneteram;Mitochondrial electron transport chain complex III (Complex III) inhibitors include azoxystrobin, picoxystrobin, pyraoxystrobin, coumoxystrobin, enoxastrobin, flufenoxystrobin, kresoxim-methyl, trifloxystrobin, fluoxastrobin, mandestrobin, orysastrobin, phenaminestrobin, and metominostrobin. obin), dimoxystrobin, pyrametostrobin, triclopyrcarb, pyraclostrobin, pyribencarb, methyltetraprole, famoxadone, fenamide fenamidone, cyazofamid, amisulbrom, fenpicoxamid, florylpicoxamid, methallylpicoxamid, ametoctradine, bifemetstrobin, Compound (1) , compound (2) , compound (3) , compound (4) , compound (5) , compound (6) , compound (7) , compound (8) , compound (9) , compound (10) , compound (11) , compound (12) , compound (13) , compound (14) , compound (15) , compound (16) , compound (17) , compound (18) , compound (19) , compound (20) , compound (21) , compound (22) , compound (23) , compound (24) , compound (25) , compound (26) , compound (27) , compound (28) , compound (29) , compound (30) , compound (31) , compound (32) , compound (33) , compound (34) , compound (35) and compound (36) the oxidative phosphorylation uncoupling inhibitor is one or more selected from the group consisting of fluazinam, dinocap, methyldinocap, and binapacryl; the ATP synthase inhibitor is one or more selected from the group consisting of triphenyltin acetate (fentin-acetate), triphenyltin chloride (fentin-chloride), and triphenyltin hydroxide (fentin-hydroxyl); and the ATP transport inhibitor is silthiofam. <4> The plant disease control composition according to <3>, wherein the mitochondrial electron transport complex II (Complex II) inhibitor is one or more selected from the group consisting of penthiopyrad, fluxapyroxad, benzovindiflupyr, bixafen, pydiflumetofen, and inpirfluxam; the mitochondrial electron transport complex III (Complex III) inhibitor is one or more selected from the group consisting of azoxystrobin, picoxystrobin, trifloxystrobin, metominostrobin, pyraclostrobin, methyltetraprole, fluoxastrobin, fenpicoxamide, florylpicoxamide, methallylpicoxamide, bifemethostrobin, compound (29), compound (30), compound (31), compound (32), compound (33), compound (34), compound (35), and compound (36); and the oxidative phosphorylation uncoupling inhibitor is fluazinam. <5> The plant disease control composition according to any one of <1> to <4>, wherein the plant disease is rice blast and the respiration inhibitor is penthiopyrad. <6> The plant disease control composition according to any one of <1> to <4>, wherein the plant disease is a disease other than rice blast. <7> The plant disease control composition according to <6>, wherein the disease other than rice blast is one or more selected from the group consisting of soybean rust, wheat leaf blight, wheat leaf rust, rice sheath blight, rice brown spot, gray mold, sclerotinia rot, powdery mildew, anthracnose, late blight, diseases caused by fungi of the genus Alternaria, and diseases caused by fungi of the genus Cercospora.<8> A method for controlling plant diseases, comprising applying the plant disease control composition according to any one of <1> to <7> to a plant disease. <9> The method for controlling plant diseases according to <8>, in which the plant disease is rice blast and the respiration inhibitor is penthiopyrad. <10> The method for controlling plant diseases according to <8>, in which the plant disease is a disease other than rice blast. <11> The method for controlling plant diseases according to <10>, in which the disease other than rice blast is one or more selected from the group consisting of soybean rust, wheat leaf blight, wheat leaf rust, rice sheath blight, rice brown spot, gray mold, sclerotinia rot, powdery mildew, anthracnose, late blight, diseases caused by fungi of the genus Alternaria, and diseases caused by fungi of the genus Cercospora. <12> The method for controlling plant diseases according to any one of <8> to <11>, wherein the application comprises one or more treatments selected from the group consisting of foliage spray treatment, seed treatment, soil treatment, and seedling box treatment.

[0014] According to one embodiment of the present disclosure, there is provided a plant disease control composition that exhibits superior plant disease control effect compared to a plant disease control composition containing tebufloquine alone as an active ingredient. According to another embodiment of the present disclosure, there is provided a plant disease control method using the plant disease control composition.

[0015] An embodiment of the present disclosure will be described below. Note that the description and examples are intended to exemplify the embodiment of the present disclosure and are not intended to limit the scope of the present disclosure.

[0016] In the present disclosure, the use of "to" indicating a numerical range means that the numerical values ​​before and after it are included as the upper and lower limits. In the numerical ranges described in stages in the present disclosure, the upper or lower limit value described in one numerical range may be replaced with the upper or lower limit value of another numerical range described in stages. Furthermore, in the numerical ranges described in the present disclosure, the upper or lower limit value of that numerical range may be replaced with a value shown in the examples.

[0017] In this disclosure, when the object contains multiple substances corresponding to each component, the amount of each component in the object means the total content or amount of the multiple substances present in the object, unless otherwise specified.

[0018] One embodiment of the present disclosure is a plant disease control composition comprising tebufloquine and a respiratory inhibitor.

[0019] The mechanism by which the plant disease control composition according to the present disclosure exerts its effect is not entirely clear, but is presumed to be as follows. The plant disease control composition according to the present disclosure applies tebufloquine, a fungicide that may not be sufficiently effective against plant diseases when used alone, in combination with a respiratory inhibitor having a different mode of action from tebufloquine. It is presumed that application of the plant disease composition according to the present disclosure produces a synergistic plant disease control effect based on the fungicidal action of tebufloquine and the fungicidal action of the respiratory inhibitor having a different mode of action, thereby enabling efficient control of various plant diseases. It is also presumed that the plant disease control composition according to the present disclosure can reduce the risk of the emergence of resistant bacteria.

[0020] The plant disease control composition according to the present disclosure can greatly contribute to the stabilization of agricultural production.

[0021] [Plant disease control composition] The plant disease control composition according to the present disclosure comprises tebufloquine and a respiratory inhibitor. In the present disclosure, the "plant disease control composition" refers to a composition that controls plant diseases caused by various pathogens such as fungi, bacteria, and viruses, which cause systemic abnormal pathological symptoms such as wilting, damping-off, yellowing, dwarfing, and spindly growth, as well as local pathological symptoms such as spots, leaf wither, mosaic, leaf curling, branch dieback, root rot, root galls, and galls, causing the plant to become sick. Details of each component contained in the plant disease control composition are described below.

[0022] <Tebufloquine> The plant disease control composition contains tebufloquine, a fungicide having a 4-quinolinol skeleton, and a compound represented by the following structural formula:

[0023]

[0024] <Respiratory inhibitor> The plant disease control composition contains a respiratory inhibitor. Examples of the respiratory inhibitor include mitochondrial electron transport chain complex I (Complex I) inhibitors, mitochondrial electron transport chain complex II (Complex II) inhibitors, mitochondrial electron transport chain complex III (Complex III) inhibitors, oxidative phosphate uncoupling inhibitors, ATP synthase inhibitors, and inhibitors related to ATP transport. One type of respiratory inhibitor may be used alone, or two or more types may be used in combination.

[0025] Mitochondrial electron transport chain complex I inhibitors include, for example, diflumetrim, tolfenpyrad, and fenazaquin.

[0026] Mitochondrial electron transport chain complex II (Complex II) inhibitors include SDHI (Succinate dehydrogenase Inhibitors: succinate dehydrogenase inhibitors, such as penthiopyrad, fluxapyroxad, penflufen, furametpyr, bixafen, benzovindiflupyr, isopyrazam, sedaxane, fluindapyr, inpyrfluxam, thifluzamide, isofetamide, and fluopyram. , pyraziflumid, isoflucipram, cyclobutrifluram, boscalid, oxycarboxin, carboxin, fenfuram, pydiflumetofen, benodanil, mepronil, flutolanil, pyrapropoyne, fenopyramide, and flubeneteram.

[0027] Examples of mitochondrial electron transport chain complex III (Complex III) inhibitors include QoI agents, QiI agents, and QoSI agents. Specifically, Complex III is the cytochrome bc1 complex that constitutes the mitochondrial electron transport chain, and compounds that inhibit the ubiquinone-binding Qo site (ubiquinol oxidase) of the cytochrome bc1 complex are defined as QoI agents, compounds that inhibit the Qi site (ubiquinone reductase) of the cytochrome bc1 complex are defined as QiI agents, and compounds that inhibit the stigmatellin-binding subsite of the Qo site (ubiquinone reductase) of the cytochrome bc1 complex are defined as QoSI agents.

[0028] The main skeletons of QoI agents are classified into methoxyacrylate, oximinoacetamide, methoxycarbamate, oximinoacetate, methoxyacetamide, dihydrodioxazine, benzylcarbamate, oxazolidinedione, imidazolino, and tetrazolinone. The QoI agents disclosed herein also include compounds with similar skeletons that do not exhibit cross-resistance to the major mutation sites in QoI-resistant bacteria, namely, the 143rd glycine to alanine substitution mutation (referred to as G143A, hereinafter), F129L, and G137R mutations in cytochrome b.

[0029] Examples of QoI agents among mitochondrial electron transport chain complex III (Complex III) inhibitors include azoxystrobin, picoxystrobin, pyraoxystrobin, coumoxystrobin, enoxastrobin, flufenoxystrobin, kresoxim-methyl, trifloxystrobin, fluoxastrobin, and mandestrobin. bin), orysastrobin, phenaminestrobin, metominostrobin, dimoxystrobin, pyrametostrobin, triclopyrcarb, pyraclostrobin, pyribencarb, methyltetraprole, famoxadone, fenamidone, bifemetostrobin, compound (1) , compound (2) , compound (3) , compound (4) , compound (5) , compound (6) , compound (7) , compound (8) , compound (9) , compound (10) , compound (11) , compound (12) , compound (13) , compound (14) , compound (15) , compound (16) , compound (17) , compound (18) , compound (19) , compound (20) , compound (21) , compound (22) , compound (23) , compound (24) , compound (25) , compound (26) , compound (27) , compound (28) , compound (29) , compound (30) , compound (31) , compound (32) , compound (33) , compound (34) , compound (35) and compound (36) Examples of QiI agents among mitochondrial electron transport chain complex III (Complex III) inhibitors include cyazofamid, amisulbrom, fenpicoxamid, florylpicoxamid, and methallylpicoxamid. Examples of QoSI agents among mitochondrial electron transport chain complex III (Complex III) inhibitors include ametoctradin.

[0030] Examples of uncoupling inhibitors of oxidative phosphorylation include fluazinam, dinocap, methyldinocap, and binapacryl. Examples of ATP synthase inhibitors include triphenyltin acetate (fentin-acetate), triphenyltin chloride (fentin-chloride), and triphenyltin hydroxide (fentin-hydroxyde). Examples of inhibitors related to ATP transport include silthiofam.

[0031] Among these, mitochondrial electron transport chain complex II (Complex II) inhibitors, mitochondrial electron transport chain complex III (Complex III) inhibitors, and oxidative phosphorylation uncoupling inhibitors are preferred as respiratory inhibitors to be used in combination with tebufloquine.

[0032] The mitochondrial electron transport chain complex II (Complex II) inhibitor to be used in combination with tebufloquine is preferably one selected from penthiopyrad, fluxapyroxad, benzovindiflupyr, bixafen, pydiflumetofen, and inpirfluxam. In particular, the combined use of tebufloquine and penthiopyrad is suitable for controlling rice blast.

[0033] In the present disclosure, "rice blast" refers to the most important disease of paddy rice (rice) caused by the rice blast fungus (Pyricularia oryzae), which occurs throughout the rice cultivation period. Rice blast causes severe damage, including leaf death, inhibited grain fertility, and reduced quality and yield. Depending on the part of the plant affected, the disease is called seedling blast, leaf blast, or panicle blast. Rice (Oryza sativa) has two ecotypes: japonica (O. sativa subsp. japonica) and indica (O. sativa subsp. indica), and each variety has its own race that can be infected.

[0034] The mitochondrial electron transport chain complex III (Complex III) inhibitor to be used in combination with tebufloquine is preferably one selected from azoxystrobin, picoxystrobin, trifloxystrobin, metominostrobin, pyraclostrobin, methyltetraprole, fluoxastrobin, fenpicoxamide, florylpicoxamide, methallylpicoxamide, bifemethostrobin, compound (29), compound (30), compound (31), compound (32), compound (33), compound (34), compound (35), and compound (36).

[0035] Fluazinam is a preferred uncoupling inhibitor of oxidative phosphorylation to be used in combination with tebufloquine.

[0036] In the plant disease control composition according to the present disclosure, when the respiratory inhibitor used in combination with tebufloquine is an SDHI agent, the mixing ratio (mass ratio) of tebufloquine to the SDHI agent is preferably 1 part tebufloquine to 0.0001 to 10 parts SDHI agent, more preferably 0.001 to 5 parts, and even more preferably 0.005 to 3.5 parts.

[0037] When the respiratory inhibitor used in combination with tebufloquine is a QoI agent, the mixing ratio (mass ratio) of tebufloquine to QoI agent is preferably 1:00001 to 10, more preferably 0.00003 to 5, and even more preferably 0.0001 to 3.5.

[0038] When the respiratory inhibitor used in combination with tebufloquine is a QiI agent, the mixing ratio (mass ratio) of tebufloquine to QiI agent is preferably 1:0.0001 to 10, more preferably 0.001 to 5, and even more preferably 0.005 to 3.5.

[0039] When the respiratory inhibitor used in combination with tebufloquine is an uncoupling inhibitor of oxidative phosphorylation, the mixing ratio (mass ratio) of tebufloquine to the uncoupling inhibitor of oxidative phosphorylation is preferably 1 part tebufloquine to 0.0001 to 10 parts uncoupling inhibitor of oxidative phosphorylation, more preferably 0.001 to 5 parts, and even more preferably 0.005 to 3.5 parts.

[0040] In the plant disease control composition according to the present disclosure, the total content of tebufloquine and the respiratory inhibitor in the plant disease control composition is not limited, but the total content (parts by mass) can be appropriately set within a range of 0.01 to 90 parts by mass per 100 parts by mass of the plant disease control composition, preferably within a range of 0.1 to 50 parts by mass per 100 parts by mass of the plant disease control composition.

[0041] The plant disease control composition may contain, in addition to tebufloquine and a respiratory inhibitor, other components described below. The other components may be used alone or in combination of two or more.

[0042] The content of the other components in the plant disease control composition is not particularly limited, but the total content (parts by mass) can be appropriately set within a range of 0.01 to 90 parts by mass per 100 parts by mass of the plant disease control composition, preferably within a range of 0.1 to 50 parts by mass per 100 parts by mass of the plant disease control composition.

[0043] The plant disease control composition according to the present disclosure can be suitably used for a wide range of plant diseases. In the present disclosure, the term "plant disease" refers to a pathogen-induced abnormal systemic pathological symptom such as wilting, damping-off, yellowing, dwarfism, or spindly growth in plants such as agricultural crops, flowers, flowering trees, or trees, or a localized pathological symptom such as spots, withered leaves, mosaic, cirring, dieback, root rot, root galls, or galls, i.e., a plant disease.

[0044] Pathogens that cause plant diseases mainly include fungi, bacteria, spiroplasma, phytoplasma, viruses, viroids, parasitic higher plants, nematodes, etc. In particular, diseases caused by fungi are called fungal diseases, and diseases caused by bacteria are called bacterial diseases.

[0045] Fungal diseases are said to account for approximately 80% of pathogens causing plant diseases. Examples of fungi (pathogens) that cause fungal diseases include Phycomycetes, Oomycetes, Zygomycetes, Ascomycetes, Basidiomycetes, and Fungi Imperfecti.

[0046] Examples of root-knot fungi include Plasmodiophora root-knot fungi, potato powdery scab fungi, and sugar beet root rot fungi. Examples of oomycetes include Phytophthora blight, downy mildew fungi, Pythium sp., and Aphanomyces sp. Examples of zygomycetes include Rhizopus sp. Examples of ascomycetes include peach leaf curl fungus, corn leaf blight fungus, rice blast fungus, powdery mildew fungus, anthracnose fungus, Fusarium head blight fungus, Gibberella bakanae fungus, and sclerotinia rot fungus. Examples of basidiomycetes include rust fungi, smut fungi, purple root rot fungus, blast fungus, and sheath blight fungus. Examples of the Fungi Imperfecti include Botrytis cinerea, Alternaria, Fusarium, Penicillium, Rhizoctonia, and Southern blight, but the fungi that cause fungal diseases are not limited to these.

[0047] Bacterial diseases are said to account for approximately 10% of pathogens that cause plant diseases. Examples of bacteria (pathogens) that cause bacterial diseases include the Proteobacteria phylum, which includes gram-negative bacteria, the Actinobacteria phylum, which includes gram-positive bacteria, and the Firmicutes phylum.

[0048] Examples of the Proteobacteria phylum include α-proteobacteria such as the genus Rhizobium and Ca. Liberibacter, β-proteobacteria such as the genus Acidovarax, Burkholderia, and Ralstonia, and γ-proteobacteria such as the genus Pseudomonas, Xanthomonas, and Erwinia. Examples of the Actinobacteria phylum include the genus Streptomyces, Clavibacter, and Curtobacterium. Examples of the Firmicutes phylum include the genus Bacillus and Clostridium. Note that bacteria that cause bacterial diseases are not limited to these.

[0049] The plant disease control composition of the present disclosure is effective against the following types of plant diseases. Specific diseases and their pathogens are listed below in parentheses, but the plant diseases against which the plant disease control composition of the present disclosure is effective are not limited to these.

[0050] Diseases in rice include blast (Magnaporthe grisea), sheath blight (Thanatephorus cucumeris), brown kernel rot (Cerato-basidium setariae), brown small kernel rot (Waitea circinata), brown sheath blight (Thanatephorus cucumeris), spherical kernel rot (Sclerotium hydrophilum), red kernel rot (Wairea circinata), false smut (Entyloma dactylidis), small kernel rot (Magnaporthe salvinii), gray kernel rot (Cerato-basidium cornig-erum), sesame leaf blight (Cochliobolus miyabeanus), streak leaf blight (Sphaerulina oryzaina), bakanae disease (Gibberella fujikuroi), seedling blight (Pythium spp., Fusarium spp., Trichoderma spp., Rhizopus spp., Rhizoctonia solani, Mucor sp.), seedling rot (Pythium spp., Achlya spp., Dictyuchus spp.), rice false smut (Claviceps virens), false smut (Tilletia barclayana), brown rice (Curvularia spp., Alternaria spp.), yellowing and withering disease (Sclerophthora macrospora), bacterial leaf blight (Xanthomonas oryzae pv. oryzae), brown stripe disease (Acidovorax avenae subsp. avenae), inner collar brown rot (Erwinia ananas), seedling blight bacterial disease (Burkholderia plantarii), culm rot bacterial disease (Burkholderia glumae), leaf sheath brown rot (Pseudomonas fuscovaginae), stem rot (Pseudomonas syringae pv.oryzae), stalk rot (Erwinia chrysanthemi), yellow wilt disease (Phytoplasma oryzae), stripe leaf blight (Rice stripe tenuivirus), dwarf disease (Rice dwarf reovirus).

[0051] Diseases in cereals include powdery mildew (Blumeria graminis f. sp. hordei; f. sp. tritici), rust (Puccinia striiformis, Puccinia graminis, Puccinia recondita, Puccinia hordei), leaf blotch (Pyrenophora graminea), net blotch (Pyrenophora teres), head blight (Gibberella zeae, Fusarium culmorum, Fusarium avenaceum, Monographella nivalis), snow mold (Typhula incarnata, Typhula ishikariensis, Monographella nivalis), loose smut (Ustilago nuda), bunt (Tilletia caries, Tilletia controversa), eyespot (Pseudocercosporella herpotrichoides), foot rot (Cerato-basidium gramineum), scald (Rhynchosporium secalis), leaf blotch (Septoria tritici), brown leaf spot (Phaeosphaeria nodorum), seedling blight (Fusarium spp., Pythium spp., Rhizoctonia spp., Septoria spp., Pyrenophora spp.), take-all (Gaeumannomyces graminis), anthracnose (Colletotrichum graminicola), ergot (Claviceps purpurea), spot blotch (Cochliobolus sativus), black chaff (Pseudomonas syringae pv. syringae), rice blast (Magnaporthe grisea).

[0052] Diseases of corn include head blight (Gibberella zeae, etc.), damping-off (Fusarium avenaceum, Penicillium spp., Pythium spp., Rhizoctonia spp.), rust (Puccinia sorghi), southern leaf blight (Cochliobolus heterostrophus), ear smut (Ustilago maydis), anthracnose (Colletotrichum graminicola), northern leaf spot (Cochliobolus carbonum), and brown stripe (Acidovorax avenae subsp.). avenae), Burkholderia andropogonis, Erwinia chrysanthemi pv. zeae, and Erwinia stewartii.

[0053] Diseases of grapes include downy mildew (Plasmopara viticola), rust (Physopella ampelopsidis), powdery mildew (Uncinula necator), black rot (Elsinoe ampelina), late rot (Glomerella cingulata, Colletotrichum acutatum), black rot (Guignardia bidwellii), fusarium wilt (Phomopsis viticola), sooty spot (Zygophiala jamaicensis), gray mold (Botrytis cinerea), and bud blight (Diaporthe medusaea), purple root rot (Helicobasidium mompa), white root rot (Rosellinia necatrix), and crown gall (Agrobacterium vitis).

[0054] Diseases of apples include powdery mildew (Podosphaera leucotricha), black spot (Venturia inaequalis), leaf spot (Alternaria mali), red spot (Gymnosporangium yamadae), monilia disease (Monilinia mali), canker (Valsa ceratosperma), ring spot (Botryosphaeria berengeriana), anthracnose (Colletotrichum acutatum, Glomerella cingulata), sooty spot (Zygophiala jamaicensis), and sooty blotch (Gloeodes pomigena), black spot (Mycosphaerella pomi), purple root rot (Helicobasidium mompa), white root rot (Rosellinia necatrix), canker (Phomopsis mali, Diaporthe tanakae), brown spot (Diplocarpon mali), fire blight (Erwinia amylovora), crown gall (Agrobacterium tumefaciens), and hairy root disease (Agrobacterium rhizogenes) can be mentioned.

[0055] Diseases of pears include black spot (Alternaria kikuchiana), black scab (Venturia nashicola), red scab (Gymnosporangium asiaticum), ring spot (Botryosphaeria berengeriana f.sp. piricola), canker (Phomopsis fukushii), bacterial branch blight (Erwinia sp.), crown gall (Agrobacterium tumefaciens), rust canker (Erwinia chrysanthemi pv. chrysanthemi), bacterial blossom rot (Pseudomonas syringae), and bacterial rot (Pseudomonas syringae). pv. syringae).

[0056] Diseases of European pears include late blight (Phytophthora cactorum, Phytophthora syringae) and bacterial branch blight (Erwinia sp.). Diseases of peaches include black scab (Cladosporium carpophilum), Phomopsis rot (Phomopsis sp.), late blight (Phytophthora sp.), anthracnose (Colletotrichum gloeosporioides), leaf curl (Taphrina deformans), bacterial bore (Xanthomonas campestris pv. pruni), and crown gall (Agrobacterium tumefaciens).

[0057] Diseases of cherries include anthracnose (Glomerella cingulata), young fruit sclerotinia (Monilinia kusanoi), brown rot (Monilinia fructicola), crown gall (Agrobacterium tumefaciens), and resin blight (Pseudomonas syringae pv. syringae).

[0058] Diseases of persimmon include anthracnose (Glomerella cingulata), leaf spot (Cercospora kaki; Mycosphaerella nawae), powdery mildew (Phyllactinia kakikora), and crown gall (Agrobacterium tumefaciens).

[0059] Diseases of plums include canker (Pseudomonas syringae pv. morsprunorum, Erwinia sp.), and diseases of kiwifruit include canker (Pseudomonas syringae pv. actinidae). Citrus diseases include black spot (Diaporthe citri), green mold (Penicillium digitatum), blue mold (Penicillium italicum), common scab (Elsinoe fawcettii), brown rot (Phytophthora citrophthora), canker (Xanthomonas campestris pv. citri), bacterial brown spot (Pseudomonas syringae pv. syringae), greening (Liberibacter asiaticus), and crown gall (Agrobacterium tumefaciens).

[0060] Examples of diseases in olives include anthracnose (Colletotrichum acutatum, Colletotrichum gloeosporioides). Examples of diseases in loquats include canker (Pseudomonas syringae pv. eriobotryae). Examples of diseases in figs include late blight (Phytophthora palmivora) and stem blight (Ceratocystis ficicola). Examples of diseases in Japanese peppers include rust (Coleosporium xanthoxyli, Uredo fagarae) and late blight (Phytophthora sp.).

[0061] Examples of diseases that affect tomatoes, cucumbers, beans, strawberries, potatoes, cabbage, eggplant, lettuce, etc. include gray mold (Botrytis cinerea). Examples of diseases that affect tomatoes, cucumbers, beans, strawberries, potatoes, rapeseed, cabbage, eggplant, lettuce, etc. include stem rot (Sclerotinia sclerotiorum). Diseases of various vegetables such as tomatoes, melons, beans, radishes, watermelons, eggplants, rapeseeds, bell peppers, spinach, and sugar beets include seedling damping-off (Rhizoctonia spp., Pythium spp., Fusarium spp., Phythophthora spp., Sclerotinia sclerotiorum, etc.). Diseases of Solanaceae plants include bacterial wilt (Ralstonia solanacearum).

[0062] Diseases of cucurbits include downy mildew (Pseudoperonospora cubensis), powdery mildew (Sphaerotheca fuliginea), anthracnose (Colletotrichum orbiculare), vine blight (Didymella bryoniae), vine wilt (Fusarium oxysporum), and late blight (Phytophthora parasitica, Phytophthora melonis, Phytophthora nicotianae, Phytophthora drechsleri, Phytophthora capsici, etc.), brown spot bacterial disease (Xanthomonas campestris pv. cucurbitae), soft rot (Erwinia carotovora subsp. carotovora), bacterial spot (Pseudomonas syringae pv. lachrymans), bacterial edge rot (Pseudomonas marginalis pv. marginalis), canker (Streptomyces sp.), hairy root disease (Agrobacterium rhizogenes), and cucumber mosaic virus.

[0063] Diseases on tomatoes include Alternaria solani, Fulvia fulva, Phytophthora infestans, Fusarium oxysporum, and Pythium rot. myriotylum, Pythium dissotocum), anthracnose (Colletotrichum gloeosporioides), canker disease (Clavibacter michiganensis), stem bacterial disease (Pseudomonas) corrugata), black spot bacterial disease (Pseudomonas viridiflava), soft rot (Erwinia carotovora subsp. carotovora), leaf club disease (Crynebacterium sp.), chlorosis (Phytoplasma) asteris) and Tabaco leaf curl subgroup III geminivirus.

[0064] Diseases of eggplant include powdery mildew (Sphaerotheca fuliginea, etc.), leaf mold (Mycovellosiella nattrassii), late blight (Phytophthora infestans), brown rot (Phytophthora capsici), bacterial brown spot (Pseudomonas cichorii), bacterial stem necrosis (Pseudomonas corrugata), bacterial stem rot (Erwinia chrysanthemi), soft rot (Erwinia carotovora subsp. carotovora), and bacterial spot (Pseudomonas sp.).

[0065] Examples of diseases in rapeseed include black spot (Alternaria brassicae), black rot (Xanthomonas campestris pv. campestris), bacterial black spot (Pseudomonas syringae pv. maculicola), and soft rot (Erwinia carotovora).

[0066] Diseases of cruciferous vegetables include black spot (Alternaria brassicae, etc.), white spot (Cercosporella brassicae), root rot (Phoma lingam), and clubroot (Plasmodiophora). brassicae), downy mildew (Peronospora parasitica), black rot (Xhanthomonas campestris pv. campestris), black spot bacterial disease (Pseudomonas syringae pv. maculicola), soft rot (Erwinia carotovora subsp. carotovora), anthracnose (Colletotrichum higgincianum), black sooty mold (Alternaria brassicicola), and white rust (Albugo macrospora).

[0067] Examples of cabbage diseases include foot rot (Thanatephorus cucumeris) and yellows (Fusarium oxysporum). Examples of Chinese cabbage diseases include bottom rot (Rhizoctonia solani) and yellows (Verticillium dahliae). Examples of broccoli diseases include flower bud rot (Pectobacterium carotovorum, etc.).

[0068] Diseases of non-heading rape include white rust (Albugo macrospora), Rhizoctonia solani, necrotic mosaic (Cucumber mosaic virus, Turnip mosaic virus), and ring disease of radish (Albugo macrospora, etc.). Diseases of lettuce include downy mildew (Bremia lactucae), rot (Pseudomonas cichorii, Pseudomonas marginalis pv. marginalis, Pseudomonas viridiflava), bacterial spot (Xanthomonas axonopodis pv. vitians), big vein disease (Lettuce big vein virus), and soft rot (Erwinia carotovora subsp. carotovora).

[0069] Diseases of leeks include rust (Puccinia allii), black spot (Alternaria porri), southern blight (Sclerotium rolfsii), white blight (Phytophthora porri), black rot (Sclerotium cepivorum), wilt (Fusarium oxysporum), downy mildew (Peronospora destructor), small sclerotial rot (Botrytis squamosa), and leaf blight (Stenphylium sp.).

[0070] Diseases on onions include Curtobacterium flaccumfaciens, Erwinia carotovora subsp. carotovora, and Pseudomonas syringae pv. syringae), Erwinia rhapontici, Burkholderia gladioli, Phytoplasma asteris, Phytoplasma asteris asteris), dry rot (Fusarium oxysporum), downy mildew (Peronospora destructor).

[0071] Garlic diseases include soft rot (Erwinia carotovora subsp. carotovora) and spring rot (Pseudomonas marginalis pv. marginalis).

[0072] Diseases of pulses (soybean, adzuki bean, etc.) include purple spot (Cercospora kikuchii), leaf spot (Cercospora sojina), black rot (Elsinoe glycines), black spot (Diaporthe phaseolorum), Rhizoctonia root rot (Rhizoctonia solani), stem rot (Phytophthora sojae), downy mildew (Peronospora manshurica), rust (Phakopsora pachyrhizi), anthracnose (Colletotrichum truncatum, etc.), and leaf burn (Xanthomonas campestris pv. glycines), bacterial spot (Pseudomonas syringae pv. glycinea), and charcoal rot (Macrophomina sp.).

[0073] Diseases of kidney beans include anthracnose (Colletotrichum lindemuthianum), bacterial wilt (Ralstonia solanacearum), halo blight (Pseudomonas syringae pv. phaseolicola), bacterial brown spot (Pseudomonas viridiflava), and leaf spot (Xanthomonas campestris pv. phaseoli).

[0074] Peanut diseases include black spot (Mycosphaerella berkeleyi), brown spot (Mycosphaerella arachidis), and bacterial wilt (Ralstonia solanacearum).

[0075] Diseases of peas include powdery mildew (Erysiphe pisi), downy mildew (Peronospora pisi), bacterial vine blight (Pseudomonas syringae pv. pisi), and bacterial vine rot (Xanthomonas campestris pv. pisi).

[0076] Diseases of broad beans include downy mildew (Peronospora viciae), late blight (Phytophthora nicotianae), and late blight (Phytophthora nicotianae). Potato diseases include summer blight (Alternaria solani), black spot (Thanatephorus cucumeris), late blight (Phytophthora infestans), silver scurf (Helminthosporium solani), dry rot (Fusarium oxysporum, Fusarium solani), powdery scab (Spongospora subterranea), bacterial wilt (Ralstonia solanacearum), black leg (Erwinia carotovora subsp. atroseptica), and common scab (Streptomyces scabies, Streptomyces acidiscabies), soft rot (Erwinia carotovora subsp. carotovora), slimy rot (Crosstridium spp.), and ring rot (Clavibacter michiganensis subsp. sepedonicus).

[0077] Diseases of sweet potato include damping-off (Streptomyces ipomoeae), root rot (Diaporthe destruens), and fusarium wilt (Fusarium oxysporum). Diseases of sugar beet include brown spot (Cercospora beticola), downy mildew (Peronospora schachtii), black root rot (Aphanomyces cochioides), snake-eye disease (Phoma betae), crown gall (Agrobacterium tumefaciens), common scab (Streptomyces scabies), and bacterial spot (Pseudomonas syringae pv. aptata).

[0078] Diseases of carrots include black leaf blight (Alternaria dauci), clubroot (Rhizobacter dauci), crown gall (Agrobacterium tumefaciens), streptomyces scab (Streptomyces spp.), and soft rot (Erwinia carotovora subsp. carotovora).

[0079] Diseases of strawberries include powdery mildew (Sphaerotheca aphanis var. aphanis), late blight (Phytophthora nicotianae, etc.), anthracnose (Glomerella cingulata, etc.), fruit rot (Pythium ultimum), bacterial wilt (Ralstonia solanacearum), bacterial angular spot (Xanthomonas campestris), and bacterial shoot blight (Pseudomonas marginalis pv. marginalis).

[0080] Diseases of tea include net blight (Exobasidium reticulatum), white spot (Elsinoe leucospila), anthracnose (Colletotrichum theae-sinensis), ring spot (Pestalothiopsis longiseta), red blight (Pseudomonas syringae pv. theae), canker (Xanthomonas campestris pv. theicola), and witches' broom (Pseudomonas sp.).

[0081] Diseases of tobacco include red scab (Alternaria alternata), powdery mildew (Erysiphe cichoracearum), anthracnose (Colletotrichum gloeosporioides), late blight (Phytophthora nicotianae), wildfire (Pseudomonas syringae pv. tabaci), bacterial yellow blight (Pseudomonas syringae pv. mellea), cavity (Erwinia carotovora subsp. carotovora), damping-off (Ralstonia solanacearum), and tobacco mosaic virus (Tobacco mosaic virus). An example of a disease in cotton is Fusarium oxysporum.

[0082] Diseases of asparagus include stem blight (Phomopsis asparagi) and brown spot (Cercospora asparagi). Diseases of sunflower include downy mildew (Plasmopara halstedii), sclerotinia sclerotiorum, angular spot (Xanthomonas campestris pv. malvacearum), hollow cavity (Erwinia carotovora subsp. carotovora), and bacterial spot (Pseudomonas syringae pv. helianthi).

[0083] Rose diseases include black scab (Diplocarpon rosae), powdery mildew (Sphaerotheca pannosa, etc.), late blight (Phytophthora megasperma), downy mildew (Peronospora sparsa), and crown gall (Agrobacterium tumefaciens). Diseases of chrysanthemums include brown spot (Septoria obesa), white rust (Puccinia horiana), late blight (Phytophthora cactorum), bacterial spot (Pseudomonas cichorii), soft rot (Erwinia carotovora subsp. carotovora), crown gall (Agrobacterium tumefaciens), hairy root disease (Agrobacterium rhizogenes), and greening disease (Phytoplasma aurantifolia).

[0084] Banana diseases include black Sigatoka disease (Mycosphaerella minima, Mycosphaerella musae, Mycosphaerella musicola, Cercospora musae, Metasphaeria musae), yellow Sigatoka disease (Pseudocercospora musae), Emza leaf spot disease (Pseudocercospora eumusae), Panama disease (Fusarium oxysporum), bunchy top disease (Banana bunchy top virus), mosaic disease (Cucumber mosaic virus), and stem rot (Ceratocystis paradoxa, Colletotrichum musae, Lasiodiplodia theobromae, Botryodiplodia theobromae, fruit drop (Colletotrichum musae), black rot (Botryodiplodia theobromae), black scab (Macrophomma musae), black mold (Rhizopus stolonifer), thin stripe (Cercospora musaecola), southern blight (Sclerotium rolfsii), anthracnose (Colletotrichum musae), round star disease (Sclerotium musae), and stem rot (Marasmius semiustus).

[0085] Diseases that occur in turf include brown patch (Rhizoctonia solani), dollar spot (Sclerotinia homoeocarpa), curvularia leaf blight (Curvularia sp.), rust (Puccinia zoysiae), helminthosporium leaf blight (Cochliobolus sp.), scald (Rhynchosporium secalis), damping-off (Gaeumannomyces graminis), anthracnose (Colletotrichum sp.), brown snow blight (Typhula incarnata), and black snow blight (Typhula ishikariensis), snow rot large-grained sclerotinia borealis, fairy ring disease (Marasmius oreades, etc.), Pythium disease (Pythium aphanidermatum, etc.), blast disease (Pyricularia grisea), large patch disease (Rhizoctonia solani), pseudo leaf rot (binucleate Rhizoctonia), bulb blight (Pseudomonas) syringae pv. atropurpurea), brown streak disease (Acidovorax avenae), Drechslera leaf blight (Drechslera sp.), Bipolaris leaf blight (Bipolaris sorokiniana), Brown spot (Drechslera poae), Summer patch (Magnaporthe poae), Necrotrophic ringspot (Ophiosphaerella korrae, Ophiosphaerella herpotricha, Ophiosphaerella spp.).

[0086] The plant disease control composition of the present disclosure is preferably used to control diseases caused by various fungi, bacteria, and viruses, and is more preferably used for diseases caused by fungi. Among fungal diseases, the composition is particularly preferably used for controlling rice blast, and diseases other than rice blast, such as soybean rust, wheat leaf blight, wheat leaf rust, rice sheath blight, rice brown spot, gray mold, sclerotinia rot, powdery mildew, anthracnose, late blight, diseases caused by fungi of the genus Alternaria, and diseases caused by fungi of the genus Cercospora. Note that, in the present disclosure, "diseases other than rice blast" refers to "plant diseases" other than rice blast.

[0087] In this disclosure, the term "powdery mildew" that causes powdery mildew is a general term for fungi that belong to the Ascomycete order, Porphyrales, and family Porphyridae. It includes diseases that infect many plants, such as vegetables, fruit trees, flowering plants, and ornamental plants, and cause diseases characterized by a white powdery appearance.

[0088] Powdery mildew fungi include many genera, such as the genus Sphaerotheca (target plants: Rosaceae; strawberry, Cucurbitaceae), the genus Erysiphe (target plants: Solanaceae; tomato, Fabaceae: pea, oaks), the genus Podosphaera (target plants: Cucurbitaceae, Rosaceae), the genus Blumeria (target plants: Poaceae, Atractylodes), the genus Golovinomyces (target plants: The genera are classified into the following genera: Neoerysiphe, Cystotheca (target plants: Fagaceae), Sawadaea (target plants: Sapindaceae; maple), Phyllactinia (target plants: Ebenaceae, Rosaceae, Moraceae), Pleochaeta, Leveillula (target plants: Solanaceae; bell pepper).

[0089] Powdery mildew fungi are further classified into three types based on their parasitic nature: ectophytic, partly ectophytic, and endophytic. Epidermal parasitic powdery mildew fungi include, for example, the genera Arthrocladiella, Blumeria, Brasiliomyces, Cystotheca, Erysiphe, Podosphaera, Sawadaea, and Typhulochaeta. Semi-endophytic powdery mildew fungi include, for example, the genera Pleochaeta and Phyllactinia. Endophytic powdery mildew fungi include, but are not limited to, those classified in the genus Leveillula.

[0090] In the present disclosure, "anthracnose" refers to a disease caused by fungi of the genus Colletotrichum. Hosts include anthracnose that occurs on a wide range of plants, including fruit trees such as apples, grapes, mangoes, avocados, blueberries, strawberries, cucumbers, garlands, watermelons, bell peppers, and tea, as well as vegetables, ornamental plants, trees, and turfgrass.

[0091] The sexual stage of some Colletotrichum species has been identified, and they are classified as Glomerella. Examples of Colletotrichum species include C. gloeosporioides, C. acutatum, C. orbiculare, C. siamense, C. nymphaeae, C. godetiae, C. fioriniae, C. dematium, C. spaethianum, C. fructicola, C. chrythanthemi, C. theobromicola, C. graminicola, C. spaethianum, C. boninense, C. Examples of suitable species include, but are not limited to, C. lindemuthianum, C. theae-sinensis, and C. truncatum.

[0092] In the present disclosure, "Alternaria" refers to pathogenic bacteria belonging to the Alternaria genus, which is an imperfect fungus. Hosts that infect and cause disease include pears, apples, tomatoes, potatoes, citrus fruits, tobacco, and leeks. Examples of Alternaria include, but are not limited to, A. alternata (A. mali, A. kikuchiana, A. citri), A. solani, A. porri, A. brassicicola, A. japonica, A. cucumerina, A. dauci, A. radicina, A. petasitis, A. brassicae, and A. sp. Apple leaf spot, pear black spot, tomato Alternaria stem blight, strawberry black spot, tangerine brown spot, and rough lemon leaf spot are morphologically similar and their hosts are determined by host-specific toxins, and therefore are classified as A. alternata.

[0093] In this disclosure, "Cercospora" refers to pathogenic fungi belonging to the imperfect genus Cercospora, including those of the genera Pseudocercospora, Cercosporella, and Mycovellosiella, which are formerly classified as Cercospora or are closely related species. They infect and cause disease in host plants such as soybean, sugar beet, asparagus, burdock, banana, chili pepper, cucumber, watermelon, melon, butterbur, eggplant, and tomato.

[0094] The diseases include soybean purple spot (Cercospora kikuchiii), sugar beet brown spot (Cercospora beticola), corn spot (Cercospora zease-maydis), soybean leaf spot fungus (Cercospora sojina), banana black Sigatoka disease (Pseudocercospora fijiensis), banana yellow Sigatoka disease (Pseudocercospora musae), Emza leaf spot disease (Pseudocercospora eumusae), tomato leaf mold (Pseudocercospora fuligena), eggplant brown round spot disease (Paracercospora egenula), pepper leaf spot (Cercospora capsici), peanut black spot (Cercospora personata), peanut brown spot (Cercospora arachidicola), cucumber, melon, watermelon, and loofah leaf spot (Cercospora citrullina), asparagus brown spot (Cercospora asparagi), burdock angular spot (Cercospora arcti-ambrosiae), butterbur brown spot (Cercospora petasitidis), Chinese cabbage and turnip white spot (Cercospora brassicae), and eggplant leaf mold (Mycovellosiella nattrassii), but are not limited to these.

[0095] The plant disease control composition according to the present disclosure can be used for a wide range of plants. The term "plant" as used herein refers to a plant that is fixed in one place, obtains nutrients from the air and water, and survives by photosynthesis. Specific examples include, but are not limited to, agricultural and horticultural crops such as rice, wheat, barley, corn, grapes, apples, pears, peaches, cherries, persimmons, citrus fruits, soybeans, green beans, strawberries, potatoes, cabbage, lettuce, tomatoes, cucumbers, eggplants, watermelons, sugar beets, spinach, snow peas, pumpkins, sugarcane, tobacco, bell peppers, sweet potatoes, taro, konjac, cotton, sunflowers, tulips, chrysanthemums, and grass.

[0096] The term "plant body" as used herein refers collectively to all parts of the plant, including, for example, stems, leaves, roots, seeds, flowers, and fruits. The term "seed" as used herein refers to a plant that stores nutrients for the germination of a young plant and is used for agricultural propagation. Specific examples include seeds of corn, soybeans, cotton, rice, sugar beets, wheat, barley, sunflowers, tomatoes, cucumbers, eggplants, spinach, snow peas, pumpkins, sugarcane, tobacco, bell peppers, rapeseed, and the like; seed potatoes of taro, potato, sweet potato, konjac, and the like; bulbs of edible lilies, tulips, and the like, and seed bulbs of scallions, and the like; and genetically modified crops that are plants created by artificially manipulating genes and do not originally exist in nature, such as soybeans, corn, cotton, and the like that have been given herbicide resistance, rice, tobacco, and the like that have been adapted to cold regions, and seeds of corn, cotton, and the like that have been given the ability to produce insecticides, and potato tubers, but are not limited to these.

[0097] When the plant disease control composition according to the present disclosure is used as a formulation, the plant disease control composition according to the present disclosure may be used as is.

[0098] Furthermore, formulations containing the plant disease control composition according to the present disclosure can be made into any formulation form according to conventional methods. The formulation form can be a dust (DL dust, FD dust, wettable powder (water dispersible granule, dry flowable, OD), water-soluble powder, powder, granule, dust granule (fine granule, fine granule), emulsion, oil, liquid, aerosol, paste, fumigation agent, fumigant, or microcapsule.

[0099] Although the content of the plant disease control composition varies depending on the formulation, it can typically be 0.01% to 50% by mass for dusts, 0.1% to 80% by mass for wettable powders, 0.5% to 50% by mass for granules, 2% to 50% by mass for emulsifiable concentrates, 1% to 50% by mass for flowable formulations, and 1% to 80% by mass for water dispersible granules. Preferably, the content is 0.05% to 10% by mass for dusts, 5% to 60% by mass for wettable powders, 5% to 50% by mass for emulsifiable concentrates, 5% to 50% by mass for flowable formulations, and 5% to 50% by mass for dry flowable formulations. The content of adjuvants can be 0% to 80% by mass, and the content of carriers can be calculated by subtracting the content of the active ingredient compound and the content of the adjuvants from 100% by mass.

[0100] The formulation is preferably an agrochemical formulation for use as a pesticide.

[0101] Here, DL powder refers to a powder formulation that suppresses scattering, with an average particle size of 20 μm or more and 20% or less of particles with a particle size of 10 μm or less, and FD powder refers to a formulation that utilizes scattering, with an average particle size of 5 μm or less.

[0102] The plant disease control composition according to the present disclosure can be used in all formulations, such as granules, powders, jumbo granules, packs, and aerosols, to be used in rice paddies and in water in seedling boxes.

[0103] These formulations can be manufactured by adding agriculturally and horticulturally acceptable additives as needed. Examples of agriculturally and horticulturally acceptable additives include carriers, surfactants, wetting agents, adhesives, thickeners, binders, antifreeze agents, colorants, and adjuvants. Examples of carriers include solid carriers, liquid carriers, and gaseous carriers. Agricultural chemical formulations can be manufactured using these additives by common manufacturing methods.

[0104] Examples of solid carriers include fine powders or granules of clays (such as clay, karyon, diatomaceous earth, bentonite, and acid clay), synthetic hydrous silicon dioxide, talc, perlite, vermiculite, pumice, and other inorganic minerals (such as sericite, quartz, sulfur, activated carbon, calcium carbonate, hydrated silica, and titanium oxide); starch, lactose, synthetic polymers such as vinyl chloride polymers and polyurethane; and plant-derived materials such as wood flour.

[0105] Examples of liquid carriers include alcohols (methanol, ethanol, isopropanol, polyethylene glycol, propylene glycol, dipropylene glycol, tripropylene glycol, glycerin, etc.), ketones (acetone, methyl ethyl ketone, etc.), aromatic hydrocarbons (benzyl alcohol, benzene, toluene, xylene, ethylbenzene, methylnaphthalene, etc.), aliphatic hydrocarbons (paraffin, n-hexane, cyclohexane, etc.), and the like. Examples of suitable solvents include hexane, kerosene, and heating oil), ethers (diethylene glycol monoethyl ether, diethylene glycol monomethyl ether, diisopropyl ether, diethyl ether, dioxane, and tetrahydrofuran), esters (propylene carbonate, ethyl acetate, butyl acetate, benzyl benzoate, isopropyl myristate, and fatty acid esters of propylene glycol), nitriles (acetonitrile and isobutyronitrile), amides (dimethylformamide, dimethylacetamide, and N-methylpyrrolidone), halogenated hydrocarbons (dichloromethane, trichloroethane, and carbon tetrachloride), animal and vegetable oils such as soybean oil and cottonseed oil, dimethyl sulfoxide, silicone oil, higher fatty acids, glycerol formal, and water.

[0106] Examples of gaseous carriers include LPG, air, nitrogen, carbon dioxide, and dimethyl ether.

[0107] The content of the carrier used in the plant disease control composition according to the present disclosure is usually 5% by mass to 99.9% by mass, and preferably 10% by mass to 98% by mass, in the plant disease control composition.

[0108] Surfactants are used for various purposes such as emulsification, dispersion, penetration, disintegration, etc. The surfactant that can be used in the plant disease control composition according to the present disclosure is not particularly limited as long as it is one that is used in ordinary pesticides, and any surfactant such as anionic surfactants, nonionic surfactants, cationic surfactants, or zwitterionic surfactants can be used.

[0109] [Method for controlling plant diseases] The method for controlling plant diseases according to the present disclosure involves applying a plant disease control composition containing tebufloquine and a respiratory inhibitor to plant diseases.

[0110] Examples of applications of the plant disease control composition according to the present disclosure include foliage spray treatment on individual plants; seedling box treatment; side-dressing application using a rice transplanter, surface application to paddy field water; soil treatments such as spraying on the soil surface, soil incorporation after spraying on the soil surface, soil injection, soil incorporation after injection in the soil, soil drench treatment, and soil incorporation after soil drench treatment; seed treatments such as spraying on plant seeds, smearing on plant seeds, application by immersion of plant seeds, application as a dressing on plant seeds, and mixing with plant seeds; and fertilizer incorporation. These applications can control plant diseases. Among these, the application is preferably one or more treatments selected from the group consisting of foliage spray treatment, seed treatment, soil treatment, and seedling box treatment.

[0111] The plant disease control composition according to the present disclosure exhibits sufficient efficacy against plant diseases in any plant disease control method by application.

[0112] The plant disease control composition according to the present disclosure can be used during the cultivation period of all crops for which pesticides are typically used, i.e., any period from before sowing to the germination period, seedling raising period, vegetative growth period, and before harvest. A preferred method of using the plant disease control composition according to the present disclosure is during the rice cultivation period, from after germination to the seedling raising period, field cultivation, and before harvest. A more preferred method of use is from the seedling raising period to before harvest.

[0113] The application amount of the plant disease control composition according to the present disclosure is not limited, but the application amount can be appropriately determined depending on factors such as the weather, environmental conditions, cultivation conditions, growth state, application time, application method, and disease severity in the target area for plant disease control. The application amount of the plant disease control composition that is effective is preferably 0.01 g to 10 kg per 10 ares, more preferably 0.05 g to 5 kg per 10 ares.

[0114] Plant diseases that can be controlled by the plant disease control method according to the present disclosure are the same as the plant diseases indicated for the plant control composition, and the same applies to plant diseases that can be more suitably controlled.

[0115] The plant disease control composition according to the present disclosure can be further mixed or used in combination with other components such as fungicides, insecticides, miticides, herbicides, plant growth regulators, microbial pesticides, spreading agents, soil conditioners, and fertilizers. The plant disease control composition according to the present disclosure and the other components can also be applied separately with a time lag.

[0116] Examples of fungicides that can be used in combination with the plant disease control composition of the present disclosure include phenylamide fungicides, hydroxy(2-amino)-pyrimidine fungicides, heteroaromatic fungicides, carboxylic acid fungicides, DHODHI fungicides, mitosis and cell division inhibitors (MBC fungicides), amino acid biosynthesis inhibitors, protein biosynthesis inhibitors, signal transduction inhibitors, lipid and cell membrane biosynthesis inhibitors, demethylation inhibitors (DMI agents), amine fungicides, 3-ketoreductase inhibitors in C4-demethylation of sterol biosynthesis, squalene epoxidase inhibitors in sterol biosynthesis, cell wall biosynthesis inhibitors, melanin biosynthesis inhibitors, host plant resistance inducers, dithiocarbamate fungicides, phthalimide fungicides, guanidine fungicides, multisite contact-active fungicides, and other fungicides.

[0117] Examples of insecticides, acaricides, and nematicides that can be used in combination with the plant disease control composition of the present disclosure include carbamate acetylcholinesterase (AChE) inhibitors, organophosphate acetylcholinesterase (AChE) inhibitors, GABA-gated chloride channel blockers, sodium channel modulators, nicotinic acetylcholine receptor (nAChR) competitive modulators, nicotinic acetylcholine receptor (nAChR) allosteric modulators, glutamate-gated chloride channel (GluCl) allosteric modulators, juvenile hormone analogs, nonspecific (multi-site) inhibitors, mite growth inhibitors, mitochondrial AT inhibitors, and the like. Examples of the antifungal agent include P synthase inhibitors, oxidative phosphorylation uncouplers that disrupt the proton gradient, nicotinic acetylcholine receptor (nAChR) channel blockers, chitin biosynthesis inhibitor type 0, chitin biosynthesis inhibitor type 1, dipteran insect molting inhibitors, ecdysone (ecdysone) receptor agonists, mitochondrial electron transport chain complex III inhibitors, mitochondrial electron transport chain complex I inhibitors (METI), voltage-dependent sodium channel blockers, acetyl-CoA carboxylase inhibitors, mitochondrial electron transport chain complex IV inhibitors, mitochondrial electron transport chain complex II inhibitors, ryanodine receptor modulators, chordotonal organ modulators, and others. The above-mentioned fungicides, insecticides, acaricides, or nematicides may be used in combination of one or more thereof, but are not limited thereto.

[0118] Examples of fungicides include benalaxyl, benalaxyl-M or kiralaxyl, furalaxyl, metalaxyl, metalaxyl-M or mefenoxam, oxadixyl, ofurase, phenylamide fungicides such as phenyl amide fungicides such as phenyl amide race; hydroxy(2-amino)-pyrimidine fungicides such as bupirimate, dimethirimol, ethirimol, etc.; heteroaromatic fungicides such as hymexazol, octhilinone, etc.; carboxylic acid fungicides such as oxolinic acid; and DHODHI fungicides such as quinofumelin, ipflufenoquin, and feneptamidoquin.

[0119] Furthermore, examples of fungicides include benomyl, carbendazim, fuberidazole, thiabendazole, thiophanate, thiophanate-methyl, diethofencarb, zoxamide, ethaboxam, pencycuron, Examples of such inhibitors include mitotic and cytotoxic agents such as fluopicolide, fluopimomide, phenamacril, metrafenone, pyriofenone, and pyridaclomethyl; and amino acid biosynthesis inhibitors such as cyprodinil, mepanipyrim, and pyrimethanil.

[0120] Further, examples of the fungicide include protein biosynthesis inhibitors such as streptomycin, kasugamycin, blasticidin S, and oxytetracycline; and signal transduction inhibitors such as fenpiclonil, fludioxonil, quinoxyfen, proquinazid, chlorzolinate, dimethachlone, iprodione, procymidone, and vinclozolin.

[0121] Furthermore, examples of fungicides include isoprothiolane, edifenphos, iprobenfos, pyrazophos, biphenyl, chloroneb, dicloran, quintozene (PCNB), tecnazene (TCNB), tolclofos-methyl, etridiazole, and the like. lipid and cell membrane biosynthesis inhibitors such as tridiazole, iodocarb, propamocarb, prothiocarb, oxathiapiprolin, fluoxathiapiprolin, natamycin or pimaricin, etc.

[0122] Furthermore, examples of fungicides include azaconazole, bitertanol, bromuconazole, cyproconazole, difenoconazole, diniconazole, diniconazole-M, [b-12.8]epoxiconazole, etaconazole, fenarimol, fenbuconazole, and fluquinone. fluquinconazole, quinconazole, flusilazole, flutriafol, hexaconazole, imazalil, imibenconazole, ipconazole, metconazole, myclobutanil, nuarimol, oxpoconazole, oxpoconazole fumarate fumarate, pefurazoate, penconazole, prochloraz, propiconazole, prothioconazole, pyrifenox, pyrisoxazole, simeconazole, tebuconazole le), tetraconazole, triadimefon, triadimenol, triflumizole, triforine, triticonazole, mefentrifluconazole, ipfentrifluconazole,Examples of such demethylation inhibitors include fluoxytioconazole and other demethylation inhibitors (DMI agents).

[0123] Furthermore, examples of fungicides include amine fungicides such as aldimorph, dodemorph, fenpropimorph, tridemorph, fenpropidin, piperalin, and spiroxamine; 3-ketoreductase inhibitors in the C4-position demethylation of sterol biosynthesis such as fenhexamid and fenpyrazamine; pyributicarb, naftifine, and the like. Squalene epoxidase inhibitors of sterol biosynthesis such as terbinafine; cell wall biosynthesis inhibitors such as polyoxins, dimethomorph, flumorph, pyrimorph, benthiavalicarb, benthiavalicarb-isopropyl, iprovalicarb, mandipropamid, and valifenalate; fthalide or phthalide), pyroquilon, tricyclazole, carpropamid, diclocymet, fenoxanil, tolprocarb, and other melanin biosynthesis inhibitors.

[0124] Furthermore, examples of fungicides include host plant resistance inducers such as acibenzolar-S-methyl, probenazole, tiadinil, isotianil, laminarin, dichlobentiazox, fosetyl, phosphorous acid, sodium phosphate, ammonium phosphate, and potassium phosphate; Examples of the fungicide include dithiocarbamate fungicides such as manzeb, maneb, metiram, propineb, thiram, zineb, ziram, and ferbam.

[0125] Furthermore, examples of fungicides include phthalimide fungicides such as captan, captafol, folpet, and fluorofolpet; guanidine fungicides such as guazatine, iminoctadine, iminoctadine albesilate, and iminoctadine triacetate; basic copper chloride, cupric hydroxide, basic copper sulfate, and organocopper compounds. Examples of suitable fungicides include multi-site contact-active fungicides such as dodecylbenzenesulfonic acid bisethylenediamine copper complex salt [II] (dodecylbenzenesulfonic acid bisethylenediamine copper [II] salt, DBEDC), chlorothalonil, sulfur, fluorimide, dichlofluanid, tolylfluanid, anilazine, dithianon, chinomethionate or quinomethionate, and extracts from cotyledons of lupin seedlings (BLAD).

[0126] Furthermore, examples of fungicides include dipymetitrone, tecloftalam, triazoxide, flusulfamide, diclomezine, diflumetrim, methasulfocarb, cyflufenamid, dodine, flutianil, and ferimzone. Other fungicides include benzophenone-3, benzophenone-4, benzophenone-5, benzophenone-6, benzophenone-7, benzophenone-8, benzophenone-9, benzophenone-10, benzophenone-11, benzophenone-12, benzophenone-13, benzophenone-14, benzophenone-15, benzophenone-16, benzophenone-17, benzophenone-18, benzophenone-19, benzophenone-20, benzophenone-21, benzophenone-22, benzophenone-23, benzophenone-24, benzophenone-25, benzophenone-26, benzophenone-27, benzophenone-28, benzophenone-29, benzophenone-30, benzophenone-31, benzophenone-32, benzophenone-33, benzophenone-34, benzophenone-35, benzophenone-36, benzophenone-37, benzophenone-38, benzophenone-39, benzophenone-40, benzophenone-41, benzophenone-42, benzophenone-43, benzophenone-44, benzophenone-45, benzophenone-46, benzophenone-47, benzophenone-48, benzophenone-49 ...

[0127] Examples of the above insecticides include acephate, dichlorvos, EPN, fenitrothion, fenamiphos, prothiofos, profenofos, pyraclofos, chlorpyrifos-methyl, chlorfenvinphos, demeton, ethion, and malathion. (malathion), coumaphos, isoxathion, fenthion, diazinon, aldicarb, propoxur, carbaryl, fenobucarb, ethiofencarb, fenothiocarb, pirimicarb, furathiocarb, hikincarb (hyquincarb), alanycarb, methomyl, cartap, thiocyclam, bensultap, dicofol, tetradifon, acrinathrin, bifenthrin, cycloprothrin, cyfluthrin, dimefluthrin, empenthrin ampenthrin), fenfluthrin, fenpropathrin, imiprothrin, metofluthrin, permethrin, phenothrin, resmethrin, tefluthrin, tetramethrin, tralomethrin, transfluthrin,Cypermethrin, deltamethrin, cyhalothrin, dimefluthrin, epsilon-metofluthrin, epsilon-momfluorothrin, kappa-bifenthrin, chloroparallethrin, kappa-tefluthrin n), momfluorothrin, heptafluthrin, meperfluthrin, tetramethylfluthrin, fenvalerate, fluvalinate, etofenprox, flufenprox, halfenprox, silafluofen, siroma Cyromazine, diflubenzuron, teflubenzuron, flucycloxuron, flufenoxuron, hexaflumuron, lufenuron, novaluron, penfluron, triflumuron, chlorfluazuron, diafenthiuron afenthiuron), methoprene, fenoxycarb, pyriproxyfen, halofenozide, tebufenozide, methoxyfenozide, chromafenozide, dicyclanil, buprofezin, hexythiazox, amitraz,Chlordimeform, pyridaben, fenpyroximate, flufenerim, pyrimidifen, tebufenpyrad, tolfenpyrad, fluacrypyrim, acequinocyl, cyflumetofen, ethiprole, fipronil pronil), etoxazole, imidacloprid, nitenpyram, clothianidin, acetamiprid, dinotefuran, thiacloprid, thiamethoxam, sulfoxaflor, triflumezopyrim, pymetrozine, bifur bifenazate, spirodiclofen, spiromesifen, spidoxamat, spiropidione, flonicamid, chlorfenapyr, pyriproxyfen, indoxacarb, pyridalyl, spinosad, abamectin, Avermectin, milbemycin, azadirachtin, nicotine, rotenone, BT bacteria, BT protein, insect pathogenic virus, emamectin benzoate, spinetoram, pyrifluquinazon, flubendiamide, chlorantraniliprole,Cyantraniliprole, cyclaniliprole, tetrachlorantraniliprole, thiolantraniliprole, fluchlordiniliprole, tetraniliprole, cyenopyrafen, spirotetramat, lepimectin mectin, metaflumizone, pyrafluprole, pyriprole, broflanilide, isocycloseram, dimefluthrin, fenazaflor, hydramethylnon, triazamate, afidopyropene, dichloromezothiazol iaz), dimpropylidaz, flupirimin, flupiroxystrobin, mivorilaner, modoflaner, tigolaner, umifoxolaner, indazapiroxamet, fenmezoditiaz, ciproflanilide, nicofluprole fluprole), oxazosulfyl, cyclopyrazoflor, benzpyrimoxan, cyhalodiamide, fluhexafon, flometoquin, flupyradifurone, flupiprole, fluensulfone, alpha-endosulfan,Examples of effective antibacterial agents include imicyafos, flumetnicame, thiapyrachlor, cibenzoxasulfyl, isofluranam, pipeflanilide, pioxaniliprole, sulfiflumin, isoflualanum, piperflanilide, and flupyroxystrobin.

[0128] Examples of the acaricides include bromopropylate, tetradifon, propargite, amitraz, fenothiocarb, hexythiazox, fenbutatin oxide, dienochlor, fenpyroximate, tebufenpyrad, pyridaben, pyrimidifen, clofentezine, etoxazole, and halfenprox. alfenprox), milbemectin, acequinocyl, bifenazate, fluacrypyrim, spirodiclofen, spiromesifen, spirobudifen, These include chlorfenapyr, avermectin, cyenopyrafen, flupentiofenox, sulfiflumin, acynonapyr, pyrimenostrobin, pyflubumide, diflovidazin, cyetpyrafen, trifluenfuronate, and cyflumetofen, bentioflumin, and bisulflufen.

[0129] Examples of the nematicides include aldoxycarb, carbofuran, carbosulfan, thiodicarb, benfuracarb, furfural, benclothiaz, cadusafos, DBCP, diclofenthion, DSP, ethoprophos, fenamiphos, and fenamiphos. Examples of suitable antibacterial agents include fensulfothion, fluazaindolizine, fluensulfone, fosthiazate, fosthietan, imicyafos, isamidofos, isazofos, oxamyl, thiaxazafen, thionazin, galquin, and tioxazafen.

[0130] The plant disease control composition according to the present disclosure can be applied by mixing with a plant growth regulator or a fertilizer. Alternatively, the plant disease control composition according to the present disclosure and the plant growth regulator or fertilizer can be applied separately with a time lag.

[0131] Examples of the plant growth regulator include ethylene agents such as ethephon; auxin agents such as indolebutyric acid and ethychlozate; cytokinins; gibberellins; auxin antagonists; dwarfing agents; and antitranspiration agents.

[0132] Examples of the above fertilizers include nitrogenous fertilizers such as urea, ammonium nitrate, magnesium ammonium nitrate, and ammonium chloride; phosphate fertilizers such as calcium superphosphate, ammonium phosphate, magnesium superphosphate, and magnesium phosphate; potassium fertilizers such as potassium chloride, potassium bicarbonate, potassium magnesium nitrate, potassium nitrate, and potassium sodium nitrate; manganese fertilizers such as manganese sulfate and magnesium manganese nitrate; and boron fertilizers such as boric acid and borates.

[0133] The present disclosure will be described in more detail below with reference to examples, but the present invention is not limited to the following examples as long as it does not depart from the gist of the present disclosure. Unless otherwise specified, "parts" are based on mass.

[0134] [Examples 1 to 16: Evaluation of plant disease control compositions] In Examples 1 to 16, the compositions were tested for rice blast (RB: Rice Blast), rice sheath blight (RSB: Rice Sheath Bright), rice brown spot (RBS: Rice Brown Spot), soybean rust (SbR: Soybean Rust), wheat leaf rust (WR: Wheat Brown Rust), barley powdery mildew (BPM: Barley Powdery Mildew), tomato late blight (LB: Late Bright), tomato gray mold (TGM: Tomato Gray Mold), and tomato gray mold-resistant strain (TGMr: Tomato Gray Mold). Control tests were conducted against cabbage black sooty mold (CA: Cabbage Alternaria Leaf Spot), sugar beet brown spot (CLS: Cercospora Leaf Spot), cabbage sclerotinia rot (CSR: Cabbage Sclerotinia Rot), wheat leaf blight (Septoria tritici), and garland chrysanthemum anthracnose (Colletotrichum acutatum), as well as soybean rust treatment tests (SbRc: Soybean Rust-curative). Details of each example are shown below.

[0135] Example 1: Rice blast control test After sowing, rice (variety: Koukaze) was grown until three true leaves had developed. A test solution prepared by diluting the plant disease control composition with water to the concentration shown in Table 1 was sprayed at 1.25 ml per pot. On the day of spraying, 1.0 × 10 seedlings were sprayed. ５ The plants were inoculated by spraying with a conidial suspension of rice blast fungus (Pyricularia oryzae) adjusted to a concentration of 100 conidia / ml. The plants were then left in a cultivation room at 23°C for 24 hours to promote disease development. Seven days after inoculation, the disease severity was examined, and the control value was calculated using the following formula (1). The presence or absence of a synergistic effect was then determined using the Colby formula (2). The results are shown in Table 1.

[0136] [Control titer] Control titer = 100 x (1 - (n / N)) Formula (1) where N = disease incidence in the untreated plot and n = disease incidence in each plot.

[0137] [Disease severity] In the above formula (1), the following evaluation values ​​were used for N and n: 0: no disease 0.1: diseased area is about 3% 0.3: diseased area is about 10% 0.8: diseased area is about 25% 1.5: diseased area is about 50% 2: diseased area is about 70% 3: diseased area is about 95%

[0138] [Evaluation of synergistic effect] Synergistic effect was evaluated using the Colby formula (2) below as an index. In the Colby formula, the theoretical value of a mixture was calculated from the control values ​​of two active ingredients A and B, and if the actual control value was greater than the theoretical value, it was determined that a synergistic effect existed. Theoretical value = A + B - (A x B / 100) Formula (2) A: Control value of active ingredient A at the same concentration as used in the mixture B: Control value of active ingredient B at the same concentration as used in the mixture

[0139]

[0140] As shown in Table 1, in Example 1, it was shown that a synergistic effect was obtained when tebufloquine (75 ppm, 150 ppm) and penthiopyrad (12.5 ppm, 25 ppm, 50 ppm) were mixed.

[0141] Example 2: Rice sheath blight control test Rice (variety: Sachikaze) was sown and grown until three true leaves had developed. A test solution prepared by diluting the plant disease control composition with water to the concentration shown in Table 2 was sprayed onto the seedlings at 2.5 ml per pot. Six hours after spraying, the seedlings were inoculated with rice sheath blight pathogen (Rhizoctonia solani) cultured on oat seeds. The seedlings were then left in an inoculation chamber at 28°C for 24 hours to promote disease development. Seven days after inoculation, the disease severity was investigated and the efficacy was evaluated. The results are shown in Table 2. The control value was calculated and the presence or absence of a synergistic effect was determined in the same manner as in Example 1.

[0142]

[0143] As shown in Table 2, Example 2 demonstrated a synergistic effect when tebufloquine (12.5 ppm, 25 ppm, 37.5 ppm, 50 ppm, 75 ppm, 100 ppm, 150 ppm) was mixed with penthiopyrad (12.5 ppm, 25 ppm, 50 ppm) or metominostrobin (200 ppm).

[0144] [Example 3: Control test of rice leaf spot disease] After sowing, rice (variety: Koukaze) was grown until two true leaves had developed. A test solution prepared by diluting the plant disease control composition with water to the concentration shown in Table 3 was sprayed at 2.5 ml per pot. Furthermore, 1.0 × 10 ４ The plants were inoculated by spraying with a spore suspension of Cochliobolus miyabeanus, which had been adjusted to a concentration of spores / ml. The plants were then left in an inoculation room at 23°C for 24 hours to promote disease development. Seven days after inoculation, the disease severity was investigated to evaluate the efficacy. The control value was calculated and the presence or absence of a synergistic effect was determined in the same manner as in Example 1.

[0145]

[0146] As shown in Table 3, Example 3 demonstrated that a synergistic effect was achieved when tebufloquine (50 ppm) and penthiopyrad (25 ppm, 50 ppm) were mixed.

[0147] Example 4: Soybean rust control test Soybeans (variety: Enrei) were sown and then grown until two true leaves had developed. A test solution prepared by diluting the plant disease control composition with water to the concentration shown in Tables 4 to 6 was sprayed at 2.5 ml per pot. One day after spraying, 1.0 x 10 ５ The soybean rust fungus (Phakopsora pachyrhizi) uredospore suspension, adjusted to uredospores / ml, was sprayed and inoculated. The plants were then left in an inoculation room at 20°C for 24 hours to promote disease development. Seven days after inoculation, the disease severity was investigated to evaluate the efficacy. The control value was calculated and the presence or absence of a synergistic effect was determined in the same manner as in Example 1.

[0148]

[0149]

[0150]

[0151] As shown in Tables 4 to 6, in Example 4, tebufloquine (10 ppm, 50 ppm) was mixed with: trifloxystrobin (0.016 ppm, 0.08 ppm, 0.4 ppm); azoxystrobin (0.016 ppm, 0.08 ppm, 0.4 ppm); pyraclostrobin (0.4 ppm, 2 ppm, 10 ppm); picoxystrobin (0.016 ppm, 0.08 ppm, 0.4 ppm); metominostrobin (0.4 ppm, 2 ppm, 10 ppm); methyltetraprole (0.4 ppm, 2 ppm, 10 ppm); fluoxastrobin (0.4 ppm, 2 ppm, 10 ppm); Mixed with benzovindiflupyr (0.4 ppm, 2 ppm, 10 ppm); Mixed with fluxapyroxad (0.4 ppm, 2 ppm, 10 ppm); Mixed with bixafen (0.4 ppm, 2 ppm, 10 ppm); Mixed with pydiflumetofen (0.4 ppm, 2 ppm, 10 ppm); Mixed with inpirfluxam (0.4 ppm, 2 ppm); Mixed with penthiopyrad (0.4 ppm, 2 ppm, 10 ppm); Mixed with fluazinam (0.4 ppm, 2 ppm, 10 ppm); Mixed with fenpicoxamid (0.4 ppm, 2 ppm, 10 ppm); It was shown that a synergistic effect was observed when mixed with florylpicoxamide (0.4 ppm, 2 ppm, 10 ppm); or when mixed with methallylpicoxamide (0.4 ppm, 2 ppm).

[0152] Example 5: Wheat leaf rust control test Wheat (variety: Norin 61) was sown and then grown until one true leaf emerged. A test solution prepared by diluting the plant disease control composition with water to the concentration shown in Tables 7 to 9 was sprayed at 2.5 ml per pot. Six hours after spraying, 1.0 x 10 ５ The wheat leaf rust fungus (Puccinia recondita) conidia suspension prepared at a concentration of 1000 / ml was sprayed and inoculated. Seven days after inoculation, the disease severity was examined to evaluate the efficacy. The control value was calculated and the presence or absence of a synergistic effect was determined in the same manner as in Example 1.

[0153]

[0154]

[0155]

[0156] As shown in Tables 7 to 9, in Example 5, tebufloquine (10 ppm, 50 ppm) was mixed with trifloxystrobin (0.016 ppm, 0.08 ppm); azoxystrobin (0.016 ppm, 0.08 ppm, 0.4 ppm); pyraclostrobin (0.4 ppm, 2 ppm, 10 ppm); picoxystrobin (0.016 ppm, 0.08 ppm, 0.4 ppm); metominostrobin (0.4 ppm, 2 ppm, 10 ppm); methyltetraprole (0.4 ppm, 2 ppm, 10 ppm); fluoxastrobin (0.4 ppm, 2 ppm, 10 ppm); Mixed with benzovindiflupyr (0.4 ppm, 2 ppm, 10 ppm); Mixed with fluxapyroxad (0.4 ppm, 2 ppm); Mixed with bixafen (0.4 ppm, 2 ppm, 10 ppm); Mixed with pydiflumetofen (0.4 ppm, 2 ppm, 10 ppm); Mixed with inpirfluxam (0.4 ppm, 2 ppm); Mixed with penthiopyrad (0.4 ppm, 2 ppm); Mixed with fluazinam (0.4 ppm, 2 ppm, 10 ppm); Mixed with fenpicoxamid (0.4 ppm, 2 ppm, 10 ppm); It was shown that a synergistic effect was observed when mixed with florylpicoxamide (0.4 ppm, 2 ppm, 10 ppm); or when mixed with methallylpicoxamide (0.4 ppm, 2 ppm).

[0157] Example 6: Barley powdery mildew control test Barley (variety: Akashinriki) was sown and grown until one true leaf emerged. A test solution prepared by diluting the plant disease control composition with water to the concentration shown in Tables 10 to 12 was sprayed onto the plants at a rate of 2.5 ml per pot. Six hours after spraying, the seedlings were contact-inoculated with conidia of barley powdery mildew ( Blumeria graminis ), and then seven days later, the degree of disease onset was examined to evaluate efficacy. The control value was calculated and the presence or absence of a synergistic effect was determined in the same manner as in Example 1.

[0158]

[0159]

[0160]

[0161] As shown in Tables 10 to 12, in Example 6, tebufloquine (10 ppm, 50 ppm) was mixed with: trifloxystrobin (0.016 ppm, 0.08 ppm, 0.4 ppm); azoxystrobin (0.016 ppm, 0.08 ppm, 0.4 ppm); pyraclostrobin (0.4 ppm, 2 ppm, 10 ppm); picoxystrobin (0.016 ppm, 0.08 ppm, 0.4 ppm); metominostrobin (0.4 ppm, 2 ppm, 10 ppm); methyltetraprole (0.4 ppm, 2 ppm, 10 ppm); Mixed with fluoxastrobin (0.4 ppm, 2 ppm, 10 ppm); Mixed with benzovindiflupyr (0.4 ppm, 2 ppm, 10 ppm); Mixed with fluxapyroxad (0.4 ppm, 2 ppm, 10 ppm); Mixed with bixafen (0.4 ppm, 2 ppm, 10 ppm); Mixed with pydiflumetofen (0.4 ppm, 2 ppm, 10 ppm); Mixed with inpirfluxam (0.4 ppm, 2 ppm, 10 ppm); Mixed with penthiopyrad (0.4 ppm, 2 ppm, 10 ppm); Mixed with fluazinam (0.4 ppm, 2 ppm, 10 ppm); It was shown that there was a synergistic effect when mixed with fenpicoxamid (0.4 ppm, 2 ppm, 10 ppm); mixed with florylpicoxamid (0.4 ppm, 2 ppm, 10 ppm); or mixed with methallylpicoxamid (0.4 ppm, 2 ppm, 10 ppm).

[0162] Example 7: Test for control of tomato late blight Tomato plants (variety: Large Fukuju) were sown and grown until three true leaves had developed. A test solution prepared by diluting the plant disease control composition with water to the concentration shown in Table 13 was sprayed at 2.5 ml per pot. One day after spraying, 1.0 × 10 ３The plants were inoculated by spraying with a zoosporangium suspension of Phytophthora infestans adjusted to a concentration of 1000 / ml. The plants were then left in an inoculation room at 20°C for 24 hours to promote disease development. Seven days after inoculation, the disease severity was investigated to evaluate the efficacy. The control value was calculated and the presence or absence of a synergistic effect was determined in the same manner as in Example 1.

[0163]

[0164] As shown in Table 13, in Example 7, tebufloquine (10 ppm, 50 ppm) was mixed with: trifloxystrobin (0.016 ppm, 0.08 ppm, 0.4 ppm); azoxystrobin (0.016 ppm, 0.08 ppm, 0.4 ppm); pyraclostrobin (0.4 ppm, 2 ppm, 10 ppm); picoxystrobin (0.016 ppm, 0.08 ppm, 0.4 ppm); metominostrobin (0.4 ppm, 2 ppm, 10 ppm); methyltetraprole (0.4 ppm, 2 ppm, 10 ppm); It was also shown that when mixed with fluoxastrobin (0.4 ppm, 2 ppm, 10 ppm), a synergistic effect was observed.

[0165] Example 8: Test for control of gray mold in tomato Tomatoes (variety: Large Fukuju) were sown and then grown until three true leaves had developed. A test solution prepared by diluting the plant disease control composition with water to the concentration shown in Tables 14 to 16 was sprayed at 2.5 ml per pot. One day after spraying, 1.0 x 10 ５ The plants were inoculated by spraying with conidia of Botrytis cinerea, the pathogen of tomato gray mold, adjusted to a concentration of conidia / ml. The plants were then left in an inoculation room at 23°C for 48 hours to promote disease development. Two days after inoculation, the severity of disease development was investigated to evaluate efficacy. The control titer was calculated and the presence or absence of a synergistic effect was determined in the same manner as in Example 1.

[0166]

[0167]

[0168]

[0169] As shown in Tables 14 to 16, in Example 8, tebufloquine (10 ppm, 50 ppm) was mixed with: trifloxystrobin (0.016 ppm, 0.08 ppm, 0.4 ppm); azoxystrobin (0.016 ppm, 0.08 ppm, 0.4 ppm); pyraclostrobin (0.4 ppm, 2 ppm, 10 ppm); picoxystrobin (0.016 ppm, 0.08 ppm, 0.4 ppm); metominostrobin (0.4 ppm, 2 ppm); methyltetraprole (0.4 ppm, 2 ppm, 10 ppm); fluoxastrobin (0.4 ppm, 2 ppm, 10 ppm); Mixed with benzovindiflupyr (0.4 ppm, 2 ppm, 10 ppm); Mixed with fluxapyroxad (0.4 ppm, 2 ppm, 10 ppm); Mixed with bixafen (0.4 ppm, 2 ppm, 10 ppm); Mixed with pydiflumetofen (0.4 ppm); Mixed with inpirfluxam (0.4 ppm, 2 ppm); Mixed with penthiopyrad (0.4 ppm, 2 ppm); Mixed with fluazinam (0.4 ppm, 2 ppm, 10 ppm); Mixed with fenpicoxamid (0.4 ppm, 2 ppm, 10 ppm); Mixed with florylpicoxamid (0.4 ppm, 2 ppm, 10 ppm); It was also shown that a synergistic effect was achieved when mixed with methallyl picoxamide (0.4 ppm, 2 ppm, 10 ppm).

[0170] Example 9: Cabbage sooty mold control test Cabbage (variety: Shikisaku) was sown and then grown until the cotyledons expanded. A test solution prepared by diluting the plant disease control composition with water to the concentration shown in Tables 17 to 19 was sprayed at 2.5 ml per pot. One day after spraying, 1.0 x 10 ５ The plants were inoculated by spraying with a conidial suspension of Alternaria brassicicola (cabbage black sooty mold) adjusted to a concentration of 100 conidia / ml. The plants were then left in an inoculation room at 20°C for 48 hours to promote disease development. Two days after inoculation, the disease severity was investigated to evaluate the efficacy. The control value was calculated and the presence or absence of a synergistic effect was determined in the same manner as in Example 1.

[0171]

[0172]

[0173]

[0174] As shown in Tables 17 to 19, in Example 9, tebufloquine (10 ppm, 50 ppm) was mixed with: trifloxystrobin (0.016 ppm, 0.08 ppm); azoxystrobin (0.016 ppm, 0.08 ppm, 0.4 ppm); pyraclostrobin (0.4 ppm, 2 ppm); picoxystrobin (0.016 ppm, 0.08 ppm); metominostrobin (0.4 ppm, 2 ppm, 10 ppm); methyltetraprole (0.4 ppm, 2 ppm, 10 ppm); fluoxastrobin (0.4 ppm, 2 ppm, 10 ppm); Mixed with benzovindiflupyr (0.4 ppm, 2 ppm); Mixed with fluxapyroxad (0.4 ppm, 2 ppm); Mixed with bixafen (0.4 ppm, 2 ppm); Mixed with pydiflumetofen (0.4 ppm, 2 ppm); Mixed with inpirfluxam (0.4 ppm, 2 ppm, 10 ppm); Mixed with penthiopyrad (0.4 ppm, 2 ppm, 10 ppm); Mixed with fluazinam (0.4 ppm, 2 ppm, 10 ppm); Mixed with fenpicoxamid (0.4 ppm, 2 ppm, 10 ppm); Mixed with florylpicoxamid (0.4 ppm, 2 ppm, 10 ppm); It was also shown that a synergistic effect was achieved when mixed with methallyl picoxamide (0.4 ppm, 2 ppm, 10 ppm).

[0175] Example 10: Soybean rust treatment test Soybeans (variety: Enrei) were sown and then cultivated until two true leaves emerged. ５The seedlings were inoculated by spraying with a uredospore suspension of soybean rust (Phakopsora pachyrhizi) adjusted to a concentration of uredospores / ml. The seedlings were then left in an inoculation room at 20°C for 24 hours to promote disease development. Two days after inoculation, 2.5 ml of a test solution prepared by diluting the plant disease control composition with water to the concentration shown in Table 20 was sprayed on the seedlings per pot. 14 days after inoculation with the test solution, the degree of disease development was investigated and the effect was evaluated. The control value was calculated and the presence or absence of a synergistic effect was determined in the same manner as in Example 1.

[0176]

[0177] As shown in Table 20, in Example 10, tebufloquine (50 ppm) was mixed with: trifloxystrobin (0.08 ppm, 0.4 ppm); azoxystrobin (0.08 ppm, 0.4 ppm); pyraclostrobin (2 ppm, 10 ppm); picoxystrobin (0.08 ppm, 0.4 ppm); metominostrobin (2 ppm, 10 ppm); methyltetraprole (2 ppm, 10 ppm); benzovindiflupyr (2 ppm, 10 ppm); fluxapyroxad (2 ppm, 10 ppm); penthiopyrad (2 ppm, 10 ppm); It was shown that there was a synergistic effect when mixed with fenpicoxamid (2 ppm, 10 ppm); mixed with florylpicoxamid (2 ppm, 10 ppm); or mixed with methallylpicoxamid (2 ppm, 10 ppm).

[0178] [Example 11: Sugar beet brown spot control test] Sugar beets (variety: Kachimaru) were sown and then cultivated until the true leaves emerged. A test solution prepared by diluting the plant disease control composition with water to the concentration shown in Table 21 was sprayed at 2.5 ml per pot. Three days after spraying, 1.0 × 10 ４ The plants were inoculated by spraying with a conidia suspension of Cercospora beticola, the pathogen of sugar beet brown spot, adjusted to a concentration of 100 conidia / ml. 14 days after inoculation, the disease severity was investigated to evaluate the efficacy. Calculation of the control value and determination of the presence or absence of a synergistic effect were carried out in the same manner as in Example 1.

[0179]

[0180] As shown in Table 21, in Example 11, it was shown that a synergistic effect was obtained when tebufloquine (50 ppm) and penthiopyrad (25 ppm, 50 ppm) were mixed.

[0181] Example 12: Test for control of gray mold in tomato - SDHI-resistant bacteria Tomato plants (variety: Large Fukuju) were sown and grown until three true leaves had developed. A test solution prepared by diluting the plant disease control composition with water to the concentration shown in Table 22 was sprayed at 2.5 ml per pot. One day after spraying, 1.0 x 10 ５ The plants were inoculated by spraying with conidia of SDHI-resistant tomato gray mold fungus ( Botrytis cinerea ) adjusted to a concentration of conidia / ml. The plants were then left in an inoculation room at 23°C for 48 hours to promote disease development. Two days after inoculation, the disease severity was investigated to evaluate the efficacy. The control value was calculated and the presence or absence of a synergistic effect was determined in the same manner as in Example 1.

[0182]

[0183] As shown in Table 22, in Example 12, it was shown that a synergistic effect was achieved when tebufloquine (25 ppm, 50 ppm) and penthiopyrad (50 ppm, 100 ppm) were mixed.

[0184] Example 13: Cabbage sclerotinia rot control test Cabbages (variety: Shikisaku) were sown and grown until four true leaves had developed. The plant disease control composition was diluted with water to the concentration shown in Table 23 to prepare a test solution. The resulting test solution was drenched in the amount shown in Table 23 per plant. Seven days after treatment, the seedlings were inoculated with mycelial fragments of cabbage sclerotinia sclerotiorum. The seedlings were then left in an inoculation chamber at 23°C for 48 hours to promote disease onset. Two days after inoculation, the disease severity was investigated and the effect was evaluated. The control value was calculated and the presence or absence of a synergistic effect was determined in the same manner as in Example 1.

[0185]

[0186] As shown in Table 23, in Example 13, it was shown that a synergistic effect was observed when tebufloquine (3.9 mg / strain, 5.85 mg / strain, 7.8 mg / strain) and penthiopyrad (7.8 mg / strain) were mixed.

[0187] Example 14: Soybean rust control test Soybeans (variety: Enrei) were sown and then cultivated until two true leaves emerged. ５ The plants were inoculated by spraying with a suspension of uredospores of soybean rust (Phakopsora pachyrhizi) adjusted to a concentration of uredospores / ml. The plants were then left in an inoculation room at 20°C for 24 hours to promote disease development. Two days after inoculation, 0.5 ml of a test solution prepared by diluting the plant disease control composition with water to the concentrations shown in Tables 24 to 26 was sprayed per pot. One day after spraying, the seedlings were inoculated and the disease severity was examined 7 days later to evaluate the efficacy. The control value was calculated and the presence or absence of a synergistic effect was determined in the same manner as in Example 1.

[0188]

[0189]

[0190]

[0191] As shown in Tables 24 to 26, in Example 14, tebufloquine (166.5 ppm, 333 ppm) was mixed with: trifloxystrobin (41.6 ppm, 166.5 ppm); azoxystrobin (41.6 ppm, 166.5 ppm); pyraclostrobin (41.6 ppm, 166.5 ppm); picoxystrobin (41.6 ppm, 166.5 ppm); metominostrobin (41.6 ppm, 166.5 ppm); methyltetraprole (41.6 ppm, 166.5 ppm); fluoxastrobin (41.6 ppm, 166.5 ppm); It was shown that a synergistic effect was observed when mixed with benzovindiflupyr (41.6 ppm, 166.5 ppm); mixed with fluxapyroxad (41.6 ppm, 166.5 ppm); mixed with pydiflumetofen (41.6 ppm, 166.5 ppm); mixed with inpirfluxam (41.6 ppm, 166.5 ppm); mixed with penthiopyrad (41.6 ppm, 166.5 ppm); mixed with fenpicoxamid (41.6 ppm, 166.5 ppm); mixed with florylpicoxamid (41.6 ppm, 166.5 ppm); or mixed with methallylpicoxamid (41.6 ppm, 166.5 ppm).

[0192] Example 15: Wheat leaf blight control test Wheat (variety: Fukusayaka) was sown and then grown until two true leaves had developed. A test solution prepared by diluting the plant disease control composition with water to the concentration shown in Tables 27 and 28 was sprayed at 0.5 ml per pot. One day after spraying, 1.0 x 10 6 The test plants were inoculated by spraying with a suspension of conidia of Septoria tritici, which had been adjusted to a concentration of 1 / ml. 14 days after inoculation, the disease severity was examined to evaluate the efficacy. The control value was calculated and the presence or absence of a synergistic effect was determined in the same manner as in Example 1.

[0193]

[0194]

[0195] As shown in Tables 27 and 28, in Example 15, tebufloquine (166.5 ppm) was mixed with: trifloxystrobin (41.6, 166.5 ppm); azoxystrobin (41.6, 166.5 ppm); pyraclostrobin (41.6, 166.5 ppm); picoxystrobin (41.6, 166.5 ppm); metominostrobin (41.6, 166.5 ppm); methyltetraprole (41.6, 166.5 ppm); fluoxastrobin (41.6, 166.5 ppm); benzovindiflupyr (41.6, 166.5 ppm); It was shown that a synergistic effect was observed when mixed with fluxapyroxad (41.6, 166.5 ppm); mixed with pydiflumetofen (41.6, 166.5 ppm); mixed with inpirfluxam (41.6, 166.5 ppm); mixed with penthiopyrad (41.6, 166.5 ppm); mixed with fenpicoxamid (41.6, 166.5 ppm); mixed with florylpicoxamid (41.6, 166.5 ppm); or mixed with methallylpicoxamid (41.6, 166.5 ppm).

[0196] Example 16: Control test of anthracnose in garland chrysanthemum After sowing, garland chrysanthemum (variety: medium-leaf garland chrysanthemum) was grown until 10 true leaves had developed. A test solution prepared by diluting the plant disease control composition with water to the concentration shown in Tables 29 and 30 was sprayed at 0.5 ml per pot. One day after spraying, 1.0 x 10 6 A conidial suspension of the Garland chrysanthemum anthracnose fungus (Colletotrichum acutatum) adjusted to a concentration of 1 / ml was sprayed and inoculated. The disease severity was investigated 14 days after inoculation to evaluate the efficacy. The control value was calculated and the presence or absence of a synergistic effect was determined in the same manner as in Example 1.

[0197]

[0198]

[0199] As shown in Tables 29 and 30, in Example 16, tebufloquine (166.5 ppm) was mixed with: trifloxystrobin (41.6, 166.5 ppm); azoxystrobin (41.6, 166.5 ppm); pyraclostrobin (41.6, 166.5 ppm); picoxystrobin (41.6, 166.5 ppm); metominostrobin (41.6, 166.5 ppm); methyltetraprole (41.6, 166.5 ppm); fluoxastrobin (41.6, 166.5 ppm); benzovindiflupyr (41.6, 166.5 ppm); It was shown that a synergistic effect was observed when mixed with fluxapyroxad (41.6, 166.5 ppm); mixed with pydiflumetofen (41.6, 166.5 ppm); mixed with inpirfluxam (41.6, 166.5 ppm); mixed with penthiopyrad (41.6, 166.5 ppm); mixed with fenpicoxamid (41.6, 166.5 ppm); mixed with florylpicoxamid (41.6, 166.5 ppm); or mixed with methallylpicoxamid (41.6, 166.5 ppm).

[0200] The disclosure of Japanese Patent Application No. 2023-161761, filed on September 25, 2023, is incorporated herein by reference in its entirety. All documents, patent applications, and technical standards mentioned herein are incorporated herein by reference to the same extent as if each individual document, patent application, and technical standard was specifically and individually indicated to be incorporated by reference.

[0201] The plant disease control composition of the present disclosure has excellent control effects against rice blast, soybean rust, wheat leaf blight, wheat brown rust, rice sheath blight, rice brown spot, gray mold, powdery mildew, anthracnose, late blight, diseases caused by fungi of the genus Alternaria, and diseases caused by fungi of the genus Cercospora, and is a useful composition for agricultural use.

Claims

1. A plant disease control composition comprising tebufloquine and a respiratory inhibitor.

2. The plant disease control composition according to claim 1, wherein the respiratory inhibitor is one or more selected from the group consisting of mitochondrial electron transport chain complex I (Complex I) inhibitors, mitochondrial electron transport chain complex II (Complex II) inhibitors, mitochondrial electron transport chain complex III (Complex III) inhibitors, uncoupling inhibitors of oxidative phosphorylation, ATP synthase inhibitors, and inhibitors related to ATP transport.

3. The mitochondrial electron transport chain complex I inhibitor is one or more selected from the group consisting of diflumetrim, tolfenpyrad, and fenazaquin; The mitochondrial electron transport chain complex II (Complex II) inhibitor is penthiopyrad, fluxapyroxad, penflufen, furametpyr, bixafen, benzovindiflupyr, isopyrazam, sedaxane, fluindapyr, inpyrfluxam, thifluzamide, isofetamide, fluopyram, pyrazam ... one or more selected from the group consisting of diflumid, isoflucipram, cyclobutrifluram, boscalid, oxycarboxin, carboxin, fenfuram, pydiflumetofen, benodanil, mepronil, flutolanil, pyrapropoyne, fenopyramide, and flubeneteram;The mitochondrial electron transport chain complex III (Complex III) inhibitor is, for example, azoxystrobin, picoxystrobin, pyraoxystrobin, coumoxystrobin, enoxastrobin, flufenoxystrobin, kresoxim-methyl, trifloxystrobin, fluoxastrobin, mandestrobin, orysastrobin, phenaminestrobin, metominostrobin, robin), dimoxystrobin, pyrametostrobin, triclopyricarb, pyraclostrobin, pyribencarb, methyltetraprole, famoxadone, fenamide fenamidone, cyazofamid, amisulbrom, fenpicoxamid, florylpicoxamid, metharylpicoxamid, ametoctradin, bifemetstrobin, compound (1) , compound (2) , compound (3) , compound (4) , compound (5) , compound (6) , compound (7) , compound (8) , compound (9) , compound (10) , compound (11) , compound (12) , compound (13) , compound (14) , compound (15) , compound (16) , compound (17) , compound (18) , compound (19) , compound (20) , compound (21) , compound (22) , compound (23) , compound (24) , compound (25) , compound (26) , compound (27) , compound (28) , compound (29) , compound (30) , compound (31) , compound (32) , compound (33) , compound (34) , compound (35) and compound (36) The plant disease control composition according to claim 2, wherein the oxidative phosphorylation uncoupling inhibitor is one or more selected from the group consisting of fluazinam, dinocap, methyldinocap, and binapacryl, the ATP synthase inhibitor is one or more selected from the group consisting of triphenyltin acetate, triphenyltin chloride, and triphenyltin hydroxide, and the ATP transport inhibitor is silthiofam.

4. The plant disease control composition according to claim 3, wherein the mitochondrial electron transport complex II (Complex II) inhibitor is one or more selected from the group consisting of penthiopyrad, fluxapyroxad, benzovindiflupyr, bixafen, pydiflumetofen, and impirfluxam, the mitochondrial electron transport complex III (Complex III) inhibitor is one or more selected from the group consisting of azoxystrobin, picoxystrobin, trifloxystrobin, metominostrobin, pyraclostrobin, methyltetraprole, fluoxastrobin, fenpicoxamide, florylpicoxamide, methallylpicoxamide, bifemethostrobin, compound (29), compound (30), compound (31), compound (32), compound (33), compound (34), compound (35), and compound (36), and the oxidative phosphorylation uncoupling inhibitor is fluazinam.

5. A plant disease control composition according to claim 1 or 2, wherein the plant disease is rice blast and the respiratory inhibitor is penthiopyrad.

6. A plant disease control composition according to claim 1 or 2, wherein the plant disease is a disease other than rice blast.

7. The plant disease control composition according to claim 6, wherein the disease other than rice blast is one or more selected from the group consisting of soybean rust, wheat leaf blight, wheat brown rust, rice sheath blight, rice brown spot, gray mold, sclerotinia rot, powdery mildew, anthracnose, late blight, diseases caused by fungi of the genus Alternaria, and diseases caused by fungi of the genus Cercospora.

8. A method for controlling plant diseases, comprising applying the plant disease control composition according to claim 1 or 2 to a plant disease.

9. The method for controlling a plant disease according to claim 8, wherein the plant disease is rice blast and the respiratory inhibitor is penthiopyrad.

10. The method for controlling plant diseases according to claim 8, wherein the plant disease is a disease other than rice blast.

11. The method for controlling plant diseases according to claim 10, wherein the disease other than rice blast is one or more selected from the group consisting of soybean rust, wheat leaf blight, wheat brown rust, rice sheath blight, rice brown spot, gray mold, sclerotinia rot, powdery mildew, anthracnose, late blight, diseases caused by fungi of the genus Alternaria, and diseases caused by fungi of the genus Cercospora.

12. The method for controlling plant diseases according to claim 8, wherein the application comprises one or more treatments selected from the group consisting of foliar spray treatment, seed treatment, soil treatment and nursery box treatment.

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