Β-ray therapy apparatus and use method therefor

Abstract

Disclosed are a β-ray therapy apparatus and a use method therefor. The present invention pertains to the field of nuclear medicine external irradiation therapy. The apparatus comprises a therapy apparatus body and a conformal structure. The therapy apparatus body comprises a β-ray source and a β-ray shielding structure. A mounting cavity and a window communicating with the mounting cavity are arranged on the β-ray shielding structure, and the β-ray source is mounted in the mounting cavity. The conformal structure comprises a conformal frame and a plurality of conformal sheets. A transmission area is arranged in the middle of the conformal frame. The conformal sheets are arranged on the conformal frame and can move toward or away from the transmission area. The positions of the conformal sheets are adjusted to form a conformal area surrounding a part to be treated in the transmission area. The β-ray source emits β-rays toward the conformal area through the window. In the present invention, conformal areas having different shapes can be formed on the basis of parts to be treated having different shapes, and the parts to be treated are then irradiated with β-rays emitted by the β-ray source through the conformal area. The present invention can use one therapy apparatus to match parts to be treated having different shapes, showing universality and adjustability.

Description

Beta ray therapy device and method of using the same Technical Field

[0001] The present invention relates to the field of nuclear medicine external irradiation therapy, and in particular to a beta ray therapy device and a method of using the same. Background Art

[0002] Beta rays emitted by radionuclides can effectively treat a variety of skin diseases, especially hemangiomas and keloids. During treatment, the beta ray applicator must be placed close to the surface of the lesion.

[0003] There are two types of beta ray applicators currently in common use: one is a small dose 32 The P applicator can be taken home by the patient after application, but it has problems such as misalignment, falling off, lack of protection, loss, and environmental pollution. For example, the Chinese patent with the authorization announcement number CN212416081U discloses a radioactive nuclide-based 32 The applicator of P includes a carrier and a base that can be buckled on the carrier. A carrier layer for carrying drugs is provided on the top of the carrier, and the carrier can be attached to the lesion area. 32 The P applicator lacks radiation protection and has low adhesion. However, to achieve the above purpose, the sealing layer, bearing layer, base layer, and base are all 3D printed and printed after 3D scanning and data analysis of the lesion morphology. Therefore, this solution needs to be made separately according to the differences of each lesion area and is not universally adjustable.

[0004] The other type is fixed shape and dosage 90 Sr- 90 The Y applicator cannot provide different doses of beta-ray therapy according to the shape, thickness, state, etc. of the lesion. For example, the Chinese patent application publication number CN102049098A discloses a 90 The strontium applicator consists of a handle and a protective screen. The handle has a groove in the middle and an applicator at the bottom. The protective screen is equipped with a retaining bead and a spring. The protective screen fits into the groove at the bottom of the handle, and the retaining bead secures the screen. This solution aims to facilitate installation and removal of the protective screen, simplifying operation and shortening radiation exposure time. However, it does not address the problem of the applicator's lack of conformability.

[0005] In summary, current applicators are either not conformable, have poor conformability, or require 3D printing to conform. It is impossible to use the same device to adapt to different lesion shapes, thicknesses, states, etc., and they are not universal and adjustable.

[0006] Summary of the Invention

[0007] The purpose of the present invention is to provide a beta-ray therapy device and a method for using the same to solve the problems existing in the above-mentioned prior art. By moving the conformal sheet on the conformal frame to different positions, conformal areas of different shapes can be formed according to the different shapes of the parts to be treated. The beta rays emitted by the beta-ray source are then used to pass through the conformal areas to irradiate the parts to be treated. The same treatment device can be used to match parts to be treated of different shapes, and has versatility and adjustability.

[0008] To achieve the above object, the present invention provides the following solutions:

[0009] The present invention provides a beta-ray therapy device, comprising a therapy device body and a conformal structure. The therapy device body comprises a beta-ray source and a beta-ray shielding structure. The beta-ray shielding structure is provided with a mounting cavity and a window communicating with the mounting cavity. The beta-ray source is mounted in the mounting cavity. The conformal structure comprises a conformal frame and a plurality of conformal sheets. A transmission area is defined in the middle of the conformal frame. The conformal sheets are disposed on the conformal frame and are capable of moving toward or away from the transmission area. By adjusting the position of the conformal sheets, a conformal area surrounding a part to be treated is formed within the transmission area. The beta-ray source emits beta rays through the window toward the conformal area.

[0010] Preferably, the conformable frame is an annular frame, the hollow area of ​​the annular frame is the transmission area, and the plurality of conformable sheets are divided into two groups, and the two groups of conformable sheets are slidably arranged on opposite sides of the annular frame.

[0011] Preferably, a plurality of first binding rings are provided on the periphery of the beta-ray shielding structure, and a plurality of second binding rings are provided on the periphery of the conformal frame, and the first binding rings and the second binding rings are respectively used to connect elastic straps.

[0012] Preferably, it includes a β-ray irradiation window, which is installed at the window. The β-ray irradiation window includes one or more blocking plates, which move relative to the window to change the size and shape of the window, so as to adjust the irradiation range of the β rays emitted by the β-ray source.

[0013] Preferably, the blocking sheet is provided on the beta ray shielding structure, and blocks or opens the window by moving toward or away from the window.

[0014] Preferably, when a plurality of blocking sheets are provided, the plurality of blocking sheets are divided into two groups, and the two groups of blocking sheets are slidably provided on two opposite sides of the β-ray shielding structure.

[0015] Preferably, the two groups of blocking plates are arranged in a one-to-one correspondence to form several pairs, and in each pair of blocking plates, one is provided with a V-shaped protrusion, and the other is provided with a V-shaped groove cooperating with the V-shaped protrusion, and the V-shaped protrusion and the V-shaped groove extend along the width direction of the window.

[0016] Preferably, it comprises a control structure, which is installed on the outside of the beta ray shielding structure. The control structure comprises a display screen, an operation button, a dose measurement structure and a prompt or alarm structure.

[0017] Preferably, an auxiliary device is included, which includes a base, a main unit and a robotic arm. The base is provided with a groove for placing the treatment device body, the main unit is fixedly installed with the robotic arm, the main unit is provided with a closed storage area, and the robotic arm is provided with a clamp for clamping the treatment device body.

[0018] The present invention also provides a method for using the beta-ray therapy device as described above, comprising the following:

[0019] The conformable frame is placed on the part to be treated, and the position of the conformable sheet is adjusted according to the shape of the part to be treated to form a conformable area surrounding the part to be treated;

[0020] Apply the plaster or gel to the area to be treated so that the applied area is flush with the surface of the conformable sheet;

[0021] The treatment device body is buckled onto the conformable frame, and a beta ray source is used to emit beta rays, which pass through the conformable area and irradiate the smeared area.

[0022] Compared with the prior art, the present invention has achieved the following technical effects:

[0023] (1) The present invention can form conformal areas of different shapes according to the shapes of the parts to be treated by moving the conformal sheet on the conformal frame to different positions. The beta rays emitted by the beta ray source are then used to irradiate the parts to be treated through the conformal areas. The same treatment device can be used to match parts to be treated of different shapes, and has versatility and adjustability.

[0024] (2) The present invention is provided with a beta-ray irradiation window. The size and shape of the window can be changed by moving the blocking plate, thereby adjusting the irradiation range of the beta-ray. On the basis of the existing conformal zone, a two-level adjustment of the beta-ray irradiation range is formed, which can more accurately control the beta-ray so that it irradiates the area to be treated, reduces the amount irradiated to non-lesion areas, and better protects normal tissues;

[0025] (3) The present invention is provided with a plurality of first binding rings on the periphery of the beta-ray shielding structure, and a plurality of second binding rings on the periphery of the conformal frame. The first binding rings and the second binding rings are used to fix the treatment device on the human body through elastic straps, thereby achieving double fixation, increasing the binding effect, better fixing the treatment device, and avoiding the influence of the displacement of the treatment device on the irradiation effect;

[0026] (4) After the conformal area is formed by the conformal sheet, the present invention applies a plaster or gel to the area to be treated, which can smear the uneven lesions to the same level, so that the area with thick lesions (thin smear thickness) receives more irradiation dose, while the area with thin lesions (thick smear thickness) receives less irradiation dose, thereby achieving the effect of intensity modulation by irradiating lesions of different degrees with different intensities. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0028] FIG1 is a front cross-sectional view of the therapeutic device body of the present invention;

[0029] FIG2 is a top view of the control structure of the present invention;

[0030] FIG3 is a top cross-sectional view of the beta-ray shielding structure of the present invention;

[0031] FIG4 is a top view of a barrier sheet according to the present invention;

[0032] Figure 5 is a front view of the base of the present invention;

[0033] Figure 6 is a top view of Figure 5;

[0034] FIG7 is a front cross-sectional view of the conformable structure of the present invention;

[0035] FIG8 is a top view of FIG7;

[0036] FIG9 is a schematic diagram of the present invention including an auxiliary device;

[0037] Figure 10 is a top view of Figure 9;

[0038] Among them, 1. Control structure; 2. β-ray shielding structure; 3. β-ray source; 4. Blocking plate; 5. Base; 6. Conformal frame; 7. Conformal plate; 8. First binding ring; 9. Display screen; 10. Operation button; 11. Second binding ring; 12. Clamp; 13. Robotic arm; 14. Host; 15. Closed storage area. DETAILED DESCRIPTION

[0039] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0040] The purpose of the present invention is to provide a beta-ray therapy device and a method for using the same to solve the problems existing in the prior art. By moving the conformal sheet on the conformal frame to different positions, conformal areas of different shapes can be formed according to the different shapes of the parts to be treated. The beta rays emitted by the beta-ray source are then used to pass through the conformal areas to irradiate the parts to be treated. The same treatment device can be used to match parts to be treated of different shapes, and has versatility and adjustability.

[0041] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the present invention is further described in detail below with reference to the accompanying drawings and specific embodiments.

[0042] As shown in Figures 1 to 8, the present invention provides a beta-ray treatment device, including a treatment device body and a conformal structure, wherein the treatment device body is mainly used to provide beta rays for irradiation, and the conformal structure is used to limit the irradiation range of the beta rays. Specifically, the treatment device body includes a beta-ray source 3 and a beta-ray shielding structure 2, and the beta-ray shielding structure 2 is provided with an installation cavity and a window communicating with the installation cavity. The beta-ray source 3 is installed in the installation cavity, and the beta-ray source 3 can be used 90 Sr- 90 Y sealed source, 32P or other radioactive sources emitting beta-rays. The beta-ray shielding structure 2 can be made of lightweight materials such as aluminum, resin, or plastic. It is used to shield the beta-ray source 3 from rays emitted in directions other than the lesion, protecting the safety of people nearby. The conformable structure includes a conformable frame 6 and multiple conformable sheets 7. The conformable frame 6 has a central portion defining a transmission zone for beta-rays to penetrate. The conformable sheets 7 are disposed on the conformable frame 6. A handle can be provided at the end of the conformable sheet 7 away from the conformable frame 6. The handle can be used to pull or push the conformable sheet 7 toward or away from the transmission zone, thereby adjusting the area and position of the blocked transmission zone. When multiple conformable sheets 7 are present, the depth of each conformable sheet 7 penetrating the transmission zone (i.e., the blocked area and position) can be adjusted. The conformable zone can be formed within the transmission zone to surround the treated area, with the shape of the conformable zone substantially equal to the shape of the treated area, by adjusting the position of the conformable sheets 7 according to the shape of the treated area. It should be noted that the more conformal sheets 7 are provided and the smaller their size, the finer the conformal zone can be achieved. The specifications and dimensions of the conformal sheets 7 are not restricted here. Furthermore, there are no requirements for either the shape of the β-ray shielding structure 2 or the shape of the window. These can be circular, rectangular, or other shapes. The opening of the window can cover the area of ​​the part to be treated, so that the conformal zone can be adjusted to cover the part to be treated. The β-ray source 3 emits β-rays within the mounting cavity, allowing the β-rays to pass through the window toward the conformal zone, thereby irradiating the lesion. In summary, the present invention moves the conformal sheets 7 on the conformal frame 6 to different positions, thereby forming conformal zones of different shapes according to the shapes of the part to be treated. The β-rays emitted by the β-ray source 3 then pass through the conformal zone to irradiate the part to be treated. This allows the same treatment device to be used to accommodate parts to be treated of different shapes, thus providing versatility and adjustability.

[0043] As shown in Figures 7 and 8 , the conformal frame 6 can be an annular frame, with the main body of the annular frame being annular. The annular shape herein can be rectangular, circular, or other ring-forming shapes, not specifically circular. The hollow area of ​​the annular frame serves as the transmissive area. The multiple conformal sheets 7 are divided into two groups, each group comprising multiple conformal sheets 7 arranged in parallel. The two groups of conformal sheets 7 are slidably disposed on opposite sides of the annular frame. By inserting or removing the conformal sheets 7 relative to each other, the shape and area of ​​the obstructed area of ​​the transmissive area can be changed. Furthermore, the conformal frame 6 can be a rectangular frame as shown in Figure 8 , with the conformal sheets 7 being elongated rectangular sheets, with the two groups of rectangular sheets positioned on opposite sides of the rectangular frame.

[0044] As shown in Figures 1, 3, 7 and 8, a number of first binding rings 8 are provided on the periphery of the β-ray shielding structure 2, and a number of second binding rings 11 are provided on the periphery of the conformal frame 6. The first binding rings 8 and the second binding rings 11 are arranged at intervals, and at least two are arranged on each side. The first binding rings 8 and the second binding rings 11 are respectively used to connect elastic straps. The elastic straps are used to fix the treatment device on the human body by using the first binding rings 8 and the second binding rings 11, and the conformal structure and the treatment device body can be fixed respectively, realizing double fixation, thereby increasing the binding effect, better fixing the treatment device, and avoiding the influence of the irradiation effect caused by the displacement of the treatment device.

[0045] As shown in Figures 1 and 4 , the beta-ray irradiation window is mounted at the window of the beta-ray shielding structure 2. The beta-ray irradiation window includes one or more barrier plates 4 made of lightweight materials such as aluminum, resin, or plastic. The barrier plates 4 can be directly inserted through the beta-ray shielding structure 2 or attached to the window structure, which is then mounted at the window. The barrier plates 4 can be moved relative to the window either horizontally or vertically, preferably by inserting or removing them longitudinally. A handle can be provided on the end of the barrier plate 4 away from the beta-ray shielding structure 2 to drive the movement of the barrier plate 4. When the treatment device is not irradiating, the barrier plate 4 can completely seal the window to prevent inappropriate emission of beta rays. When only one barrier plate 4 is installed, the window size can be adjusted by reciprocating movement of the barrier plate 4 in one direction. When multiple barrier plates 4 are installed, the window size can be adjusted while still fitting the shape of the treatment area by moving different barrier plates 4. Adjusting the window size can adjust the irradiation range of the beta-rays emitted by the beta-ray source 3. It can be seen from this that the present invention can form a two-level adjustment method to adjust the β-ray irradiation range on the basis of using the existing conformal structure to form a conformal zone, which can more accurately control the β-rays so that they are irradiated to the area to be treated, reduce the amount irradiated to non-lesion areas, and better protect normal tissues.

[0046] More specifically, the beta ray shielding structure 2 may be provided with a through hole or a groove, and the blocking sheet 4 may be inserted into the through hole or the groove, and can block or open the window by moving toward or away from the window.

[0047] When multiple barrier sheets 4 are provided, the barrier sheets 4 are divided into two groups, each group including multiple barrier sheets 4 arranged in parallel, and the two groups of barrier sheets 4 are slidably arranged on opposite sides of the beta ray shielding structure 2. When the beta ray shielding structure 2 is a rectangular frame, the barrier sheets 4 are rectangular sheets, and the rectangular sheets are arranged on opposite sides of the rectangular frame.

[0048] Two sets of barrier sheets 4 are arranged in a one-to-one correspondence, forming several pairs. In each pair of barrier sheets 4, one is provided with a V-shaped protrusion, and the other is provided with a V-shaped groove that cooperates with the V-shaped protrusion. The V-shaped protrusion and the V-shaped groove extend along the width of the window. When the barrier sheets 4 are close to each other, the V-shaped protrusion can be inserted into the V-shaped groove to form a top and bottom shield, thereby reducing the gap and improving the blocking effect of beta rays.

[0049] As shown in Figures 1 and 2, the device comprises a control structure 1, which is mounted outside a beta-ray shielding structure 2. The control structure 1 includes a display screen 9, operating buttons 10, a dose measurement structure, and a prompt or alarm structure. The dose measurement structure is used to measure the radiation dose received by the lesion. The display screen 9 is used to display the measured radiation dose received by the lesion. When the required dose or time is about to be received, the prompt or alarm structure can sound a prompt or alarm. The operating buttons 10 can control the operation of the control structure 1, such as starting or stopping the device and setting the dose prompt value.

[0050] As shown in Figures 5, 6, 9, and 10, the device includes an auxiliary device, which includes a base 5, a main unit 14, and a robotic arm 13. The base 5 is provided with a groove for placing the treatment device body, which can support the treatment device body when the treatment device is idle. The main unit 14 can be fixedly mounted with the robotic arm 13 to support the movement of the robotic arm 13. At the same time, the main unit 14 can also be provided with a closed storage area 15, which can be used to store the base 5 and the conformable structure, as well as the treatment device body. The base 5 and the conformable structure can both be placed sideways in the closed storage area 15.

[0051] The robotic arm 13 is provided with a clamp 12 for clamping the treatment device body. Through the setting of the robotic arm 13 and the clamp 12, on the one hand, the robotic arm 13 can be used to move the treatment device body to the part to be treated and maintain the corresponding position state for irradiation. On the other hand, the used treatment device body can be sent back to the closed storage area 15.

[0052] When using the device of the present invention to treat proliferative diseases such as scars, hemangiomas, tumors, and localized scleroderma, beta-ray irradiation windows of varying opening sizes can be obtained by adjusting the position of the barrier sheet 4. By adjusting the conformal sheet 7, conformal zones of varying opening sizes can be obtained. The application shape can be selected based on the lesion's shape, thickness, and condition, adjusting the irradiation range of the beta-ray source 3. The treatment device body and conformal structure can be secured to the human body surface with elastic straps, preventing them from falling off. The clamp 12 and robotic arm 13 can be used to secure the treatment device in place and to store it in a closed storage area 15, facilitating easy use and recovery.

[0053] As shown in Figures 1 to 10, the present invention also provides a method for using the beta-ray therapy device described above, comprising the following:

[0054] The conformable frame 6 is placed on the part to be treated and can be fixed with the second binding ring 11 and the elastic band. The position of the conformable sheet 7 is adjusted according to the shape of the part to be treated to form a conformable area surrounding the part to be treated, thereby achieving the effect of shape adjustment.

[0055] Use burn plaster, scar plaster or gel to apply to the area to be treated, and apply the uneven lesions to the same level. The applied area is flush with the surface of the conformable sheet 7, so that the area with thick lesions (thin application thickness) receives more irradiation dose, while the area with thin lesions (thick application thickness) receives less irradiation dose, so that lesions of different degrees can be irradiated with different intensities to achieve the effect of intensity modulation.

[0056] The treatment device body is buckled onto the conformal frame 6, and can be clamped by the mechanical arm 13, or fixed by the first binding ring buckle 8 and the elastic strap, and the β-ray source 3 is used to emit β-rays, which pass through the conformal area and irradiate the coated area.

[0057] In order to better illustrate the use of the present invention, the following specific examples are provided:

[0058] A patient has a scar on his forearm that requires treatment. The required irradiation dose for treatment is calculated based on the size of the scar and set as the prompt threshold of the control structure 1. The shape of the beta-ray irradiation window is adjusted to be the same as the scar shape by adjusting the position of the blocking plate 4. The scar area is surrounded by a conformable structure and fixed with an elastic band. The conformable plate 7 is adjusted to form a conformal area that is consistent with the shape and size of the scar. After using gel to create a flat surface on the uneven scar area, the treatment device body is fixed to the patient's forearm with the elastic band to start irradiation treatment. When the required irradiation dose for treatment is reached, the control structure 1 emits a prompt sound, the elastic band can be loosened, and the treatment device body can be stored in the closed storage area 15 using the clamp 12 and the robotic arm 13.

[0059] The present invention uses specific examples to illustrate the principles and implementation methods of the present invention. The above examples are only intended to help understand the method and core concept of the present invention. At the same time, those skilled in the art will find that the specific implementation methods and application scopes may vary based on the concept of the present invention. In summary, the contents of this specification should not be construed as limiting the present invention.

Claims

1. A beta-ray therapy device, characterized in that: The invention comprises a treatment device body and a conformable structure, wherein the treatment device body comprises a β-ray source and a β-ray shielding structure, wherein the β-ray shielding structure is provided with an installation cavity and a window communicating with the installation cavity, wherein the β-ray source is installed in the installation cavity; wherein the conformable structure comprises a conformable frame and a plurality of conformable sheets, wherein a transmission zone is provided in the middle of the conformable frame, wherein the conformable sheets are arranged on the conformable frame, and wherein the conformable sheets can be moved toward or away from the transmission zone, and a conformable zone surrounding a part to be treated is formed in the transmission zone by adjusting the position of the conformable sheets; and wherein the β-ray source emits β-rays toward the conformable zone through the window.

2. The beta-ray therapy device according to claim 1, characterized in that: The conformable frame is an annular frame, the hollow area of ​​the annular frame is the transmission area, and the plurality of conformable sheets are divided into two groups, and the two groups of conformable sheets are respectively slidably arranged on two opposite sides of the annular frame.

3. The beta-ray therapy device according to claim 1, characterized in that: A plurality of first binding rings are arranged at the periphery of the beta-ray shielding structure, and a plurality of second binding rings are arranged at the periphery of the conformable frame. The first binding rings and the second binding rings are respectively used for connecting elastic binding bands.

4. The beta-ray therapy device according to any one of claims 1 to 3, characterized in that: It includes a beta-ray irradiation window, which is installed at the window. The beta-ray irradiation window includes one or more blocking plates, which move relative to the window to change the size and shape of the window, so as to adjust the irradiation range of the beta rays emitted by the beta-ray source.

5. The beta-ray therapy device according to claim 4, characterized in that: The blocking sheet is arranged on the beta ray shielding structure, and blocks or opens the window by moving toward or away from the window.

6. The beta-ray therapy device according to claim 5, characterized in that: When a plurality of blocking sheets are provided, the plurality of blocking sheets are divided into two groups, and the two groups of blocking sheets are respectively slidably provided on two opposite sides of the β-ray shielding structure.

7. The beta-ray therapy device according to claim 6, characterized in that: The two groups of blocking sheets are arranged one by one to form a plurality of pairs. In each pair of blocking sheets, one is provided with a V-shaped protrusion, and the other is provided with a V-shaped groove matching with the V-shaped protrusion. The V-shaped protrusion and the V-shaped groove extend along the width direction of the window.

8. The beta-ray therapy device according to claim 1, characterized in that: It comprises a control structure, which is installed on the outside of the beta ray shielding structure. The control structure comprises a display screen, an operation button, a dose measurement structure and a prompt or alarm structure.

9. The beta-ray therapy device according to claim 1, characterized in that: The auxiliary device comprises a base, a main unit and a mechanical arm. The base is provided with a groove for placing the treatment device body. The main unit is fixed with the mechanical arm. The main unit is provided with a closed storage area. The mechanical arm is provided with a clamp for clamping the treatment device body.

10. A method for using the beta-ray therapy device according to any one of claims 1 to 9, characterized in that: Includes the following: The conformable frame is placed on the part to be treated, and the position of the conformable sheet is adjusted according to the shape of the part to be treated to form a conformable area surrounding the part to be treated; Apply the plaster or gel to the area to be treated so that the area after application is flush with the surface of the conformable sheet; The treatment device body is buckled onto the conformable frame, and the beta ray source is used to emit beta rays, which pass through the conformable area and irradiate the coated area.

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