Method for treating pain

Abstract

The invention relates to medicine, and more particularly to algology, and can be used in the treatment of pain. The present method includes oral administration of a pharmaceutical composition. Administration begins with a minimum single dose comprising: 1 drop or granule of the composition, dissolved in 15 ml of water, per 10 kg of the patient's weight. The minimum single dose is administered every 15 minutes. An individually tailored single dose is determined by adding up the minimum doses of the composition which induce a subjective sensation of a decrease in pain. The composition is administered in the individually tailored single dose at a dosage frequency of not more than 8 times a day on the first day and not more than four times a day on the second and subsequent days. The pharmaceutical composition contains equal quantities of Eupatorium perfoliatum in a 3D dilution, China officinalis, Secale comutum, Arnica montana in a 3C dilution, Rhus toxicodendron in a 4C dilution, Aconitum napellus, Belladonna, Bryonia alba, Ipecacuanha, Nux vomica in a 5C dilution, Mercurius solubilis in a 6C dilution, Abrotanum, Gallicum acidum, Heloderma suspectum, Senecio aureus in a 7C dilution, and Stramonium in a 9C dilution. The invention provides for a significant decrease in the pain sensations experienced by the patient, irrespective of the source of and reasons for the pain.

Description

[0001]METHOD FOR TREATING PAIN DESCRIPTION Field of the invention: The invention relates to the field of medicine, in particular to the use of homeopathic medicines for treating pain [A61K 36 / 00, A61K 31 / 00, A61P29 / 00]. State of the art: According to the definition, pain is an unpleasant sensory and psychoemotional experience associated with existing or possible tissue damage or described in terms of such damage (International Association for the Study of Pain, 1986). The perception of pain is important for the normal functioning of the body. Intense and prolonged pain can lead to such serious disorders that it can be considered an independent pathology. Therefore, as well as for the prevention of chronic pain, it is important to prescribe pain therapy in a timely manner. If the pain has become chronic,its therapy should be complex and consist of many components. Pain treatment requires an interdisciplinary approach involving specialists of different profiles. There are several known mechanisms of pain occurrence (THOMAS CEGLAH, Handbook. Pain Treatment, Moscow, 2012, Medpress-inform, pp. 18-24). Thus, one of them is peripheral sensitization - a process in which unmyelinated C-fibers and thick myelinated Aδ-fibers of peripheral nerves, which have different excitation conduction speeds, conduct nerve excitation arising from stimulation of pain receptors to nerve centers. When a nerve is damaged by one or another nature, peripheral sensitization occurs, accompanied by an increase in the number of sodium channels and an increase in the excitability of the nerve. In this case, pathological processes in tissues lead to a decrease in the excitability threshold of pain receptors. The so-called "sleeping" pain receptors are activated,having a higher threshold of excitability. The following act as mediators in these receptors: histamine; bradykinin; serotonin; prostaglandins. In case of untimely or inadequate treatment, including insufficient or inadequate pain therapy, its chronicization occurs, in which various types of receptors of the peripheral nervous system participate: sodium channel isoforms; vanilloid receptors in hyperalgesia with a sensation of heat; TRPM8 channels in hyperalgesia with a sensation of cold. Other mechanisms affect the violation of the regulatory function of the autonomic nervous system. Increased activity of the sympathetic division of the nervous system, causing a decrease in blood flow in tissues and the delivery of nutrients to them, enhances peripheral sensitization. In addition, during an inflammatory reaction, macrophages, secreting tumor necrosis factor α (TNFα) and other proinflammatory cytokines, also contribute to peripheral,and central sensitization. Central sensitization. Peripheral nerve damage can disrupt pain processing at the spinal cord level. Sensitization of C-fibers leads to increased release of glutamate, aspartate, and substance P, as well as sensitization of wide-dynamic-range (WDR) neurons. They received their name due to their ability to converge on themselves the conduction of excitation of numerous peripheral neurons. Such sensitization facilitates the occurrence of an action potential, and impulses caused by non-painful stimuli, reaching the myelinated fibers of multireceptor neurons, cause the appearance of mechanical allodynia. Long-term potentiation of pain impulses in the dorsal horns of the spinal cord leads to the activation of a number of receptors,such as: glutamine NMDA-type; metabotrophic glutamine; neurokinin-1 receptors. As a result of activation of these receptors, the intracellular concentration of calcium increases, which in turn leads to activation of calcium-dependent enzymes and phosphorylation of intracellular proteins, including glutamine receptors. This enhances the effect of glutamate and increases cell excitability. Gate control theory. In 1965, Melzack and Wall put forward a theory according to which the conduction of excitation to the brain is modulated at the level of the spinal cord by a system that controls the flow of impulses. The conduction of pain impulses can be inhibited by peripheral and descending nerve pathways. Further conduction of excitation by the SDD neuron is under the modulating influence of other neurons: sensitive Aβ fibers suppress conduction,acting on glutamine receptors and the release of glutamate; descending nerve pathways inhibit the transmission of impulses to the SDD neurons via the serotonin mediator; descending nerve pathways in inhibitory interneurons enhance the release of endorphins - enkephalin, dynorphin. The sympathetic system and pain. The growth of autonomic nerve fibers into the area of ​​damage can lead to increased sympathetic activity in the affected area, which entails a change in blood flow and increased pain. Chronic pain. An important component of the learning process at the level of individual neurons is a long-term change in the function of a nerve cell under the influence of an external stimulus. Severe or repeated pain irritation can cause such a change in the function of the entire nervous system. Long-term synaptic potentiation in the spinal cord and impaired pain suppression also lead to the formation of pain memory. Thus, if we consider pain as an independent pathology,that is, a disease that requires treatment regardless of the cause that caused it and regardless of the treatment aimed at the cause, an adequate method of such treatment may be a method that provides for an impact on all the above-mentioned causes of pain and its chronicity. It should be noted that treatment as such, in accordance with Federal Law No. 323-FZ of 21.11.2011 (as amended on 24.07.2023) "On the Fundamentals of Protecting the Health of Citizens in the Russian Federation" (as amended and supplemented, entered into force on 01.09.2023) in the Russian Federation, should be understood as a set of medical interventions performed as prescribed by a health care professional, the purpose of which is to eliminate or alleviate the manifestations of a disease or diseases or conditions of the patient, restore or improve his health, ability to work and quality of life. The prior art includes a THREE-STEP PAIN TREATMENT SCHEME proposed by the WHO (see, for example, Julie LV Shaw et al., Pharmacogenetics of Chronic Pain Management,Clinical Biochemistry, 47(13-14), DOI:10.1016 / j.clinbiochem.2014.05.065). The scheme provides for a step-by-step introduction of drugs depending on the degree and nature of pain. At the first stage, non-steroidal anti-inflammatory drugs (NSAIDs) are used; if the pain is not relieved, it is recommended not to switch to another NSAID, but to use weak opioids, and if they are ineffective in treating pain, they switch to using strong opioid drugs. The scheme is highly effective, however, starting from the first stage, it can lead to significant side effects. Thus, the use of NSAIDs is associated with increased tissue bleeding due to a violation of the platelet link of hemostasis (accordingly, NSAIDs are contraindicated in the case of initial hypocoagulation of any genesis), nephrotoxic effects (contraindicated in patients over 65 years of age, as well as in patients with creatinine clearance less than 50 ml / min),ulcerogenic action (contraindicated in patients with gastrointestinal tract (GIT) diseases), increased risk of recurrent myocardial infarction (contraindicated in patients with a history of infarction and heart rhythm disturbances), with the development of other side effects with a period of use longer than 3 days. Thus, even the first stage of the proposed scheme: 1) cannot be used for a long time; 2) cannot be used in a large number of patients who may need pain treatment due to the underlying disease or conditions unrelated to it; 3) is associated with a proven risk of developing a significant number of side effects. The second and third stages have an even greater number of contraindications for use, restrictions on use and can lead to severe side effects. In addition, each stage of the proposed scheme has a selective effect on the previously described mechanisms of pain. Thus,NSAIDs have as their point of action inhibition (selective, non-selective, partially selective) of cyclooxygenase (COX: COX-1, COX-2, COX-3); opiates and opioids provide hyperpolarization of the posterior horns of the spinal cord, which leads to a violation of the release of pain mediators, and also inhibit enkephalinases. However, none of the drugs has a comprehensive effect on all links in the development of pain syndrome. The prior art also knows a METHOD USED FOR THE TREATMENT OF PAIN (RU 2253477 (C1), published: 10.06.2005), including the use of morphine in combination with a homeopathic dilution of the same drug, administered in standard and ultra-low (C200) doses in order to achieve an analgesic effect (see example 12). With regard to the specified combination, the effect of increasing the threshold of nociceptive reaction, i.e. reducing pain sensitivity, has been shown in comparison with the independent use of morphine in a standard dose. However,the method is not without the disadvantages of the three-stage pain treatment scheme given above, since it involves the use of a narcotic opioid analgesic, which, as was indicated earlier, has an effect on only one link in the pain mechanism, and a list of contraindications and side effects (respiratory depression, cough reflex, bronchoconstriction, sedation, euphoria / dysphoria, nausea, vomiting, miosis, muscle rigidity, myoclonus, convulsions, vasodilation, bradycardia, myocardial depression, hyperalgesia, immunosuppression, suppression of the cellular link of immunity). In addition, the method is not applicable to the treatment of mild to moderate pain, which, however, requires action no less frequently than severe pain and can lead to a chronic course of pain. The closest analogue of the proposed solution is the METHOD OF PAIN REDUCTION (G Orellana Alvarellos et al., Сomplex homeopathic injection therapy in the management of pain in patients after breast cancer treatment,Altern Ther Health Med. 2010 Jan-Feb; 16 (1): 54- 9), which includes the injection of the complex homeopathic preparation Traumel S. This method helps to reduce pain, but, as the author himself points out, it is of little use in cases of severe pain, since it does not have sufficient analgesic activity. In this regard, this complex homeopathic preparation is administered together with procaine. Insufficient analgesic effectiveness is due to the composition of the preparation. Its method of administration, on the one hand, causes inhibition of pain impulses from the main source of pain due to the occurrence of pain from the introduction (gate control theory), but on the other hand, it causes locality and insufficiency of the analgesic effect due to the lack of influence on central sensitization. The consequence of the lack of influence on central sensitization is not only the insufficiency of the analgesic effect, but also the impossibility of reducing pain in the foci,remote from the injection site. Thus, the method has limited indications for use and low effectiveness in pain treatment. Disclosure of the essence of the invention: The technical problem solved by the invention is the elimination of the disadvantages of the prototype. The technical result of the invention is to increase the effectiveness of pain treatment. The increase in the effectiveness of pain treatment is objectively manifested by a significant decrease in the patient's pain sensations, which occurs after the start of his treatment. In addition, the proposed method helps to reduce pain regardless of the source and causes of its occurrence. The specified technical result provides a method for treating pain, including oral administration of a pharmaceutical composition; administration begins with a minimum single dose of 1 drop or granule of the composition dissolved in 15 ml of water,per 10 kg of patient weight; the minimum single dose is taken every 15 minutes; an individual single dose is determined by summing up the minimum single doses of the composition that contributed to the subjective feeling of pain reduction; the composition is taken in an individual single dose with a frequency of administration on the first day of no more than 8 times, on the second and subsequent days - no more than 4 times, while the pharmaceutical composition contains Eupatorium perfoliatum taken in equal amounts in dilution D3; China officinalis, Secale cornutum, Arnica montana in dilution C3; Rhus toxicodendron in dilution C4; Aconitum napellus, Belladonna, Bryonia alba, Ipecacuanha, Nux vomica in dilution C5; Mercurius solubilis in dilution C6; Abrotanum, Gallicum acidum, Heloderma suspectum, Senecio aureus in dilution C7; Stramonium in dilution C9. In particular, the method for treating pain further includes the step of determining the disease or condition that contributed to the occurrence of pain or is accompanied by pain,and using at least one additional pharmaceutical composition in a dosage form selected from the group: drops, rub, granules, ointment, gel, oil, suppositories, injection solutions. In particular, in the event of pain arising due to rhinitis and / or sinusitis, additionally use a pharmaceutical composition of equal amounts of Hydrastis canadensis in a D4 dilution; Allium sulphate in a D6 dilution; Dulcamara, Gelsemium sempervirens, Kalium bichromicum, Pulsatilla pratensis, Sabadilla, Sticta pulmonatia in a C3 dilution; Aralia racemose in a C5 dilution; Arsenicum album in a C6 dilution. In particular, in the event of pain arising due to acute tonsillitis and / or pharyngitis, use a composition of equal amounts of Eucalyptus globulus in a D3 dilution; Lycopodium clavatum, Phytolacca decandra in C3 dilution; Barium carbonicum, Hepar sulfur in C5 dilution; Apis mellifica, Lachesis mutus in C6 dilution. In particular, in case of pain associated with laryngitis,a composition of equal amounts of Arum triphyllum, Selenium metallicum in a C3 dilution; Ailanthus glandulosa in a C4 dilution; Argentum nitricum, Cuprum metallicum, Phosphorus in a C5 dilution; Agaricus muscarius, Magnesium muriaticum, Populus candicans in a C6 dilution; Carbo vegetabilis in a C8 dilution is used. In particular, in case of pain due to chronic tonsillitis and / or chronic sinusitis, a composition of equal amounts of Thuja occidentalis in a D3 dilution is used; Arum triphyllum, Spigelia anthelmia in a C3 dilution; Agraphis nutans in a C4 dilution; Aurum metallicum, Baryta muriatica, Teucrium marum verum in a C5 dilution; Mezereum in a C6 dilution; Silicea terra in a C8 dilution is used; Calcarea phosphorica in C9 dilution. In particular, in case of pain arising in the context of acute otitis and / or eustachitis,a composition of equal amounts of Plantago major in a D3 dilution; Cactus grandifloras in a D6 dilution; Camphor in a C2 dilution; Capsicum annuum in a C3 dilution; Manganum aceticum in a C4 dilution; Chamomilla recutita, Petroleum in a C5 dilution; Ferrum phosphoricum in a C6 dilution is used. In particular, in case of pain due to bronchitis and / or pneumonia, a composition of equal amounts of Arundo mauritanica in a D3 dilution is used; Rumex crispus, Sanguinaria canadensis, Spongia tosta, Drosera in a C3 dilution; Ambra grisea, Bromium in a C4 dilution; Causticum, Hyoscyamus niger in a C5 dilution; Eupatorium perfoliatum; Antimonium tartaricum in a C6 dilution; Phosphorus in a C7 dilution is used; Sticta pulmonatia dilution C12. In particular, in case of a combination of pain and cough, a composition of equal amounts of Drosera, Sanguinaria canadensis, Spongia tosta, Rumex crispus in dilution C3; Ambra grisea, Bromium in dilution C4; Causticum,Hyoscyamus niger in C5 dilution; Antimonium tartaricum in C6 dilution; Phosphorus in C7 dilution. In particular, in case of pain due to bruise and / or sprain and / or bone fracture, use a composition of equal amounts of Arnica montana in D2 dilution; Bellis perennis in D6 dilution; Rhus Toxicodendron, Ruta graveolens, Symphytum in C3 dilution; Ledum palustre in C4 dilution; Hypericum perforatum in C5 dilution; Bryonia alba in C6 dilution; Apis mellifica in C7 dilution; Lachesis mutus in C8 dilution; Calcarea phosphorica in C9 dilution. In particular, in case of pain due to thermal or chemical damage to the skin, use a composition of equal amounts of Calendula officinalis in D2 dilution; Hamamelis virginica in dilution D3; Urtica urens in dilution D6; Cantharis vesicatoria in dilution C3; Causticum, Thuja occidentalis in dilution C5; Apis mellifica, Arsenicum album, Hepar sulfur C6. In particular,In case of pain arising due to conjunctivitis, a composition of equal amounts of Euphrasia officinalis in a dilution of D3; Ranunculus bulbosus in a dilution of C2; Agaricus muscarius, Arundo mauritanica, Clematis erecta in a dilution of C3; Argentum nitricum in a dilution of C5; Natrium muriaticum in a dilution of C6 is used. In particular, in case of pain arising due to hordeolum or chalazion, a composition of equal amounts of Platanus occidentalis in a dilution of D3; Badiaga in a dilution of C2; Thuja occidentalis in a dilution of C3; Staphisagria in a dilution of C4; Hepar sulfur in a dilution of C5; Pulsatilla pratensis in a dilution of C6; Conium maculatum in a dilution of C8 is used. In particular, in case of pain arising against the background of pulpitis or alveolitis, a composition of equal amounts of Plantago major in dilution D3, Aconitum napellus, Hypericum perforatum in dilution C3; Chamomilla in dilution C5 is used.Pulsatilla pratensis in C8 dilution; Mercurius solubilis in C9 dilution; Hepar sulfur in C12 dilution. In particular, in case of pain due to arthropathy, use a composition of equal amounts of Harpagophytum procumbens in D3 dilution; Colchicum autumnale in D4 dilution; Benzoicum acidum, Ledum palustre in C3 dilution; Antimonium crudum, Causticum, Strontium carbonicum in C4 dilution; Bambusa arundinacea, Lycopodium clavatum in C5 dilution, Calcarea carbonica, Aranea diadema in C6 dilution. In particular, in case of pain due to cardiomyopathy, use a composition of equal amounts of Crataegus oxyacantha in D1 dilution; Convallaria majalis in C3 dilution; Digitalis purpurea in C4 dilution; Laurocerasus in C5 dilution; Latrodectus mactans, Naja tripudians in C6 dilution; Kalium carbonicum in C7 dilution; Moschus in C9 dilution; Lilium lancifolium in C12 dilution. In particular, in case of pain associated with cholecystitis,or cholangitis and / or biliary dyskinesia, or hepatitis, use a composition of equal amounts of Myrica cerifera, Leptandra virginica in D2 dilution; Dioscorea villosa in D3 dilution; Chelidonium majus in D6 dilution; Carduus marianus, Lycopodium clavatum in C3 dilution; Ptelea trifolita, Taraxacum officinales in C4 dilution, Chamomilla recutita, Natrium sulfuricum in C5 dilution; Magnesia muriatica in C6 dilution. In particular, in case of pain due to hemorrhoids and / or anal fissure, use a composition of equal amounts of Aesculus hippocastanum in D3 dilution; Ratanhia in D5 dilution; Collinsonia сanadensis, Hamamelis virginica, Paeonia officinalis in C3 dilution; Nitricum acidum in C4 dilution; Calcarea fluorica in C5 dilution; Vipera berus in C6 dilution. In particular, in case of pain arising against the background of neuralgia or neuritis,a composition of equal amounts of Chelidonium majus in a dilution of D3; Verbascum Thapsus, Xantolylum fraxinfeum, Plantago major in a dilution of C3, Lepidium bonariensa in a dilution of C5; Cinnabaris, Dulcamara in a dilution of C6; Asa foetida in a dilution of C7; Cedron in a dilution of C8; Ignatia amara in a dilution of C9; Platinum metallicum in a dilution of C12 is used. In particular, in case of pain due to teething, a composition of equal amounts of Rheum palmatum in a dilution of C3; Kreosotum in a dilution of C4; Phytolacca decandra in a dilution of C5; Chamomilla recutita in a dilution of C6; Kalium bromatum in a dilution of C7; Cypripedium pubescens in a dilution of C8 is used; Belladonna, Calcarea carbonica in C9 dilution. In particular, in case of pain arising due to adhesions in the abdominal cavity and / or pelvic cavity, a composition of equal amounts of Thiosinaminum in D4 dilution; Fluoricum acidum,Ranunculus bulbosus in C3 dilution; Nitricum acidum in C4 dilution; Graphites in C5 dilution; Silicea terra in C6 dilution; Causticum in C7 dilution; Iodium in C9 dilution. In particular, in case of pain arising from premenstrual syndrome, use a composition of equal amounts of Agnus castus in D4 dilution; Murex purpurea in C3 dilution; Cimicifuga racemose, Kalium carbonicum in C6 dilution; Calcarea carbonica in C7 dilution; Natrium muriaticum, Pulsatilla pratensis, Conium maculatum in C8 dilution; Chamomilla recutita in C9 dilution. In particular, in case of pain arising from glomerulonephritis, use a composition of equal amounts of Solidago virgaurea, Eucalyptus globules in C2 dilution; Apis mellifica, Uva ursi at C3 dilution; Arsenicum album, Brachyglottis repens at C4 dilution; Serum anguillae at C5 dilution; Terebinthinae oleum at C6 dilution; Mercurius corrosives at C7 dilution. In particular,In case of pain arising due to pyelonephritis, a composition is used consisting of equal amounts of Belladonna, Benzoicum acidum in a C3 dilution; Eupatorium perfoliatum in a C4 dilution; Sarsaparilla officinalis in a C5 dilution; Lycopodium clavatum in a C6 dilution; Apis mellifica in a C7 dilution; Colchicum autumnale in a C8 dilution; Hepar sulfur in a C9 dilution. In particular, in case of pain arising due to urethritis or cystitis, a composition is used consisting of equal amounts of Nitricum acidum, Pareira brava in a D6 dilution; Petroselinum sativum, Copaiva officinalis in a C3 dilution; Cantharis vesicatoria, Cubeba in a C4 dilution; Chimaphila umbellate in a C5 dilution; Doryphora decemlineata in a C7 dilution; Sepia officinalis in a C9 dilution. In particular, in case of pain arising due to urolithiasis, a composition of equal amounts of Coccus cacti in C3 dilution; Pareira brava in C4 dilution; Arnica montana, Calcarea carbonica, Chamomilla recutita is used.Colocynthis in C5 dilution; Berberis vulgaris in C6 dilution; Ocimum canum, Plumbum metallicum in C6 dilution. In particular, in case of pain associated with herpetic eruptions, use a composition of equal amounts of Rhus toxicodendron in D3 dilution; Cantharis vesicatoria in D4 dilution; Sepia officinalis in D5 dilution; Ranunculus bulbosus, Sarsaparilla in C3 dilution; Thuja occidentalis in C4 dilution; Alnus rubra in C5 dilution; Arsenicum album, Dulcamara in C6 dilution; Natrium muriaticum in C7 dilution; Graphites in C8 dilution; Hypericum perforatum in C12 dilution. In particular, in case of a combination of pain and flatulence, a composition of equal amounts of Aethusa cynapium, Asa foetida, Dioscorea villosa in C3 dilution; Carbo vegetabilis, Lycopodium clavatum, Chamomilla recutita in C4 dilution; Anisum stellatum, is used.Ambra grisea in C5 dilution; Calcarea phosphorica in C7 dilution; Argentum nitricum in C9 dilution. In particular, in case of pain due to prostatitis, use a composition of equal amounts of Cucurbita pepo in D3 dilution; Clematis erecta in C3 dilution; Euphrasia officinalis in C4 dilution; Fabiana imbricate in C5 dilution; Pulsatilla pratensis in C6 dilution; Colchicum autumnale in C7 dilution; Dulcamara in C8 dilution; Hepar sulfur in C12 dilution. In particular, in case of pain due to prostate adenoma, use a composition of equal amounts of Aloe socotrina in D4 dilution; Cicuta virosa in D5 dilution; Sabal serrulata in D6 dilution; Pareira brava, Allium sativum in C3 dilution; Digitalis at C4 dilution; Selenium metallicum at C5 dilution; Conium maculatum at C6 dilution; Iodium at C7 dilution; Thuja occidentalis at C8 dilution; Staphysagria at C9 dilution. In particular,In case of pain arising due to inflammatory-necrotic processes in soft tissues, use a composition of equal amounts of Myrica cerifera in dilution D3; Calendula officinalis in dilution C4; Apis mellifica, Hamamelis virginica in dilution C5; Lachesis mutus in dilution C6; Bufo rana in dilution C7; Mercurius solubilis, Silicea terra, Hepar sulfur in dilution C8; Calcarea carbonica in dilution C9. In particular, in case of pain arising due to gastritis, use a composition of equal amounts of Anamirta cocculus in dilution C5; Antimonium crudum in dilution C6; Kalium carbonicum in dilution C7; Pulsatilla pratensis in dilution C8; Anacardium orientale in dilution C10; Argenutm nitricum in dilution C12. In particular, in case of pain arising against the background of esophagitis,a composition of equal amounts of Quassia amara in dilution D3; Cascarilla in dilution C2; Zingiber officinale in dilution C3; Kreosotum in dilution C4; Niccolum metallicum in dilution C5; Natrium carbonicum in dilution C6; Robinia pseudacacia in dilution C7 is used. In particular, in case of pain arising due to gastric ulcer and / or duodenal ulcer, a composition of equal amounts of Robinia in dilution C3; Manganum aceticum, Sulfuricum acidum in dilution C5, Ammonium muriaticum in dilution C6; Causticum in dilution C8 is used. In particular, in case of pain arising due to damage to the integrity of the skin due to hyperkeratosis, a composition of equal amounts of Arum triphyllum in dilution D6; Petroleum in dilution D9; Cundurango at C3 dilution; Graphites at C4 dilution; Antimonium crudum, Arsenicum album, Natrium muriaticum, Nitricum acidum at C5 dilution; Alnus rubra,Mercurius solubilis in C6 dilution; Lycopodium clavatum in C8 dilution. In particular, in case of pain arising from myositis, use a composition of equal amounts of Arnica montana, Rhus Toxicodendron, Ruta graveolens in D3 dilution; Eupatorium perfoliatum, Ledum palustre in D4 dilution; Bryonia alba in D5 dilution; Hypericum perforatum in D6 dilution; Formicicum acidum in C3 dilution; Magnesium phosphoricum in C7 dilution. In particular, in case of pain arising from varicose veins of the lower extremities, use a composition of equal amounts of Aesculus hippocastanum in D3 dilution; Hamamelis virginiana in D4 dilution; Arnica montana in D5 dilution; Ruta graveolens, Lycopodium clavatum, Pulsatilla pratensis, Rhus toxicodendron in C3 dilution; Causticum in C5 dilution; Vipera berus, Ferrum metallicum in C6 dilution; Fluoricum acidum in C7 dilution; Zincum metallicum in C8 dilution. In particular,in case of pain arising from erosive lesions of the skin and / or mucous membranes, use a composition of equal amounts of Alnus rubra in a C3 dilution; Phytolacca decandra in a C4 dilution; Thuja occidentalis in a C5 dilution; Argentum metallicum, Sulfuricum acidum in a C6 dilution; Mercurius iodatus ruber in a C7 dilution; Carbolicum acidum in a C9 dilution. In particular, in case of pain arising from caries, use a composition of equal amounts of Plantago major in a C3 dilution; Mezereum in a C4 dilution; Thuja occidentalis in a C5 dilution; Kreosotum in a C6 dilution; Fluoricum acidum in a C7 dilution; Calcarea fluorica in a C8 dilution; Staphysagria in a C9 dilution. In particular, in case of pain arising from muscle spasms and / or cramps,a composition of equal amounts of Colocynthis in a dilution of D3; Passiflora incarnata in a dilution of C2; Anamirta cocculus in a dilution of C3; Caulophyllum thalictroides in a dilution of C4; Magnesium phosphoricum in a dilution of C5; Agaricus muscarius in a dilution of C6; Gelsemium in a dilution of C7 is used. In particular, in case of pain arising from pancreatitis, a composition of equal amounts of Acidum silicicum in a dilution of D9; Momordica balsamina in a dilution of C2; Iris versicolor in a dilution of C3; Spongia tosta in a dilution of C4; Phosphorus in a dilution of C5; Iodium C6; Conium maculatum in a dilution of C7 is used. In particular, in case of pain arising from periodontosis, a composition of equal amounts of Arnica montana in a dilution of D3 is used; Cistus canadensis, Kreosotum in C3 dilution; Causticum, Fluoricum acidum, Hecla lava in C4 dilution; Carbo vegetabilis, Staphisagria in C5 dilution; Calcarea carbonica, Thuja occidentalis,Phosphorus in C6 dilution; Plumbum metallicum in C7 dilution; Mercurius solubilis in C9 dilution. In particular, in case of pain arising from ascites, use a composition of equal amounts of Squilla maritima in D4 dilution; Helleborus niger in C3 dilution; Apocynum cannabinum in C4 dilution; Spigelia anthelmia in C5 dilution; Ammonium carbonicum in C6 dilution; Apis mellifica in C9 dilution; Mercurius sulfuricus in C10 dilution. In particular, in case of pain arising from metrorrhagia, use a composition of equal amounts of Erigeron canadense in D2 dilution; Sedum telephium in D3 dilution; Ustilago maydis in D4 dilution; Crocus sativus in C2 dilution; Cinnamomum ceylanicum in C3 dilution; Erodium cicutarium in C4 dilution; Millefolium in C5 dilution; Kalium ferrocyanatum in C6 dilution; Phosphorus in C7 dilution. Implementation of the invention: If the patient has pain syndrome, regardless of the causes that caused it,and also at any localization and intensity of pain, carry out oral administration of a pharmaceutical composition containing Eupatorium perfoliatum taken in equal quantities in a dilution of D3; China officinalis, Secale cornutum, Arnica montana in a dilution of C3; Rhus toxicodendron in a dilution of C4; Aconitum napellus, Belladonna, Bryonia alba, Ipecacuanha, Nux vomica in a dilution of C5; Mercurius solubilis in a dilution of C6; Abrotanum, Gallicum acidum, Heloderma suspectum, Senecio aureus in a dilution of C7; Stramonium in a dilution of C9. The administration begins with a minimum single dose of 1 drop or granule of the composition, dissolved in 15 ml of water, per 10 kg of weight. The minimum single dose is taken with a frequency of 15 minutes between doses. The individual single dose is determined by adding up the minimum single doses that contributed to the reduction of pain according to the patient's subjective sensations. Determining the individual single dose allows the composition to be taken in the amountwhich in a specific patient leads to obtaining a rapid and pronounced effect. The composition is taken in an individual single dose until the pain completely disappears, with a frequency of administration on the first day of no more than 8 times, on the second and subsequent days - no more than 4 times. Such a dosing regimen allows to exclude pain breakthroughs. In this case, the implementation of the method may also include an additional determination of the disease or condition that contributed to the occurrence of pain or is accompanied by pain, and the use of at least one additional pharmaceutical composition in a dosage form selected from the group: drops, rubbing, granules, ointment, gel, oil, suppositories, injection solutions. The use of at least one composition is understood as the delivery to the patient's body of at least one composition in addition to that described above. In this case, such delivery, depending on the dosage form used, can be carried out by oral administration, rinsing, rubbing,spraying, irrigation, instillation, application, rectal or vaginal administration. The mechanism of action of homeopathic medicinal products: In accordance with the Federal Law of April 12, 2010 N 61-FZ "On the Circulation of Medicines", which entered into force on September 1, 2010, a homeopathic preparation should be understood as a medicinal product produced or manufactured from a pharmaceutical substance or pharmaceutical substances in accordance with the requirements of general pharmacopoeial articles for homeopathic medicinal products or in accordance with the requirements of the pharmacopoeia of the country of manufacture of such a medicinal product. The following dosages (dilutions) of the components can be used in homeopathic compositions according to the invention: preparation according to the decimal dilution scale (1:10), designated in the description text as D; preparation according to the centesimal dilution scale (1:100),is designated in the text of the description as C. All methods for obtaining the components / substances of the homeopathic composition and the homeopathic composition itself, as well as the methods for carrying out dilutions are known to a specialist in this field, and the specific sequence of actions and techniques is disclosed in published sources, links to which are given below in this description. The mechanism of action of homeopathic medicinal products, according to the latest research, is associated with the formation of nanoparticles of active substances in the form of bubbles (see, for example, the study of homeopathic preparations Cuprum metallicum and Gelsemium sempervirens using the nuclear magnetic resonance (NMR) method (VAN WASSENHOVEN M, GOYENS M, HENRY M, CAPIEAUX E, DEVOS P.,Nuclear Magnetic Resonance characterization of traditional homeopathically manufactured copper (Cuprum metallicum) and plant (Gelsemium sempervirens) medicines and controls. Homeopathy. 2017. 106(4):223–239. doi: 10.1016 / j. homp.2017.08.001). These nanoparticles are capable of triggering nonspecific and specific reactions, activating neuroendocrine mechanisms, heat shock proteins, and cytokines. The key role of nanobubbles in the mechanism of action of homeopathic medicines is also indicated by studies by DEMANGEAT JL. Gas nanobubbles and aqueous nanostructures: the crucial role of dynamization. Homeopathy. 2015. 104(2):101– 15. doi: 10.1016 / j.homp.2015.02.001, as well as BELLAVITE P, MARZOTTO M, OLIOSO D, MORATTI E, CONFORTI A. High-dilution effects revisited. 1. Physicochemical aspects. Homeopathy. 2014 Jan;103(1):4-21. doi:10.1016 / j.homp.2013.08.003. Review. | PubMed; BELLAVITE P, MARZOTTO M, OLIOSO D, MORATTI E,CONFORTI A. High-dilution effects revisited. 2. Pharmacodynamic mechanisms. Homeopathy. 2014.103(1):22—43. doi: 10.1016 / j.homp.2013.08.002. Using proton NMR, scientists demonstrated spatial changes around the structure of a dissolved homeopathic substance, affecting the change in the physicochemical properties of the solvent in solutions with dilutions up to C9, C10, C12–C24, which are preserved even after dilution of C12 (DEMANGEAT JL. Nanosized solvent superstructures in ultramolecular aqueous dilutions: twenty years' research using water proton NMR relaxation. Homeopathy. 2013. 102(2):87—105. doi: 10.1016 / j.homp.2013.01.001). These studies have been confirmed by fluorescence methods and atomic force microscopy (ELIA^V, AUSANIO G, GENTILE F, GERMANO R, NAPOLI E, NICCOLI M. Experimental evidence of stable water nanostructures in extremely dilute solutions,at standard pressure and temperature. Homeopathy. 2014. 103(1):44–50. doi: 10.1016 / j. homp.2013.08.004). Similar conclusions were made in the study of spectral changes in solutions of homeopathic medicinal products with the addition of solvatochromic dyes as indicators of the polarity of the medium (3 Interaction of homeopathic potencies with the water soluble solvatochromic dye bis-dimethylaminofuchsone. Part 1: pH studies. Homeopathy. 2017. 106(1):37–46. doi: 10.1016 / j.homp.2017.01.001). Despite the difficulties in studying and explaining the physicochemical properties of homeopathic medicinal products (HMPs) and their compositions, molecular changes in the environment due to the effect of HMPs on them are clearly shown. For example, one study showed significant expression of various genes in a human prostate cell line under the influence of Apis mellifica C3, C5, C7, C9, C12, C15, C30 GLP for 24 hours, regardless of the degree of dilution (BIGAGLI E, LUCERI C, DEI A, BERNARDINI S,DOLARA. Effects of Extreme Dilutions of Apis mellifica Preparations on Gene Expression Profiles of Human Cells. Dose Response.2016. 6;14(1):1559325815626685. doi: 10.1177 / 1559325815626685). Similar work was carried out on a line of human neurons with treatment with Gelsemium sempervirens GLP C2, C3, C4, C9 and C30, and changes in the expression levels of 56 genes were also obtained (MARZOTTO M, OLIOSO D, BRIZZI M, TONONI P, CRISTOFOLETTI M, BELLAVITE P. Extreme sensitivity of gene expression in human SHSY5Y neurocytes to ultra-low doses of Gelsemium sempervirens. / / BMC Complement Altern Med. 2014.14:104. doi: 10.1186 / 1472— 6882—14— 104). Using cytochemical techniques and quantitative PCR (polymerase chain reaction), Jyoti and Tandon demonstrated the feasibility of drug toxicity testing in mouse embryonic stem cells using drugs such as Strychnos nux-vomica (Nux vomica) C30 and Sepia officinalis (Sepia) C30 (JYOTI S,TANDON S. Impact of homeopathic remedies on the expression of lineage differentiation genes: an in vitro approach using embryonic stem cells. Homeopathy. 2016 May; 105 (2): 148— 59. doi: 10.1016 / j.homp. 2015.11.002). The biological effects of homeopathic medicinal products at the molecular level obtained in such studies indicate the presence of an effect and partially explain the mechanism of action on the human body. Further studies to establish the mechanism of action of homeopathic preparations are still underway. The composition according to the claimed invention: The selection of homeopathic medicinal products (HMPs), which can be used to treat pain as ingredients of the composition, was made on the basis of an analysis of 15,245 descriptions of pain syndrome of various localization, etiology and nature of the course, as a result of which 1012 single-component HMPs were selected that are capable of influencing the course of pain syndrome (the EMS-DAR DB was used to automate the analysis and selection,certificate No. 2013618704). Then we selected those components (single-component homeopathic medicinal products) that could be used in most cases - 95 homeopathic single-component medicinal products, from which, based on experience, selection of optimal ratios and experimental data, complex homeopathic compositions were compiled. Further research allowed us to establish that one of the obtained compositions has an effect on reducing pain regardless of the source, cause and localization of pain. The remaining compositions were compiled depending on the demonstrated properties to reduce pain depending on the localization, causes and sources of its occurrence. Based on the conducted research, as well as on known experimental data and information on the effect on pain, the applicant created a pharmaceutical composition from components in certain homeopathic dilutions,capable of influencing the pain syndrome regardless of the source, causes and localization of pain. The said composition includes Eupatorium perfoliatum taken in equal quantities in D3 dilution; China officinalis, Secale cornutum, Arnica montana in C3 dilution; Rhus toxicodendron in C4 dilution; Aconitum napellus, Belladonna, Bryonia alba, Ipecacuanha, Nux vomica in C5 dilution; Mercurius solubilis in C6 dilution; Abrotanum, Gallicum acidum, Heloderma suspectum, Senecio aureus in C7 dilution; Stramonium in C9 dilution. Such homeopathic medicinal products as Eupatorium perfoliatum, Bryonia alba, Rhus Toxicodendron are known for relieving pain at rest, with muscle fatigue, anxiety, chills, pain in bones and joints, sharp, shooting, unbearable. Their action is associated with the prevention of peripheral sensitization and the inhibition of activation of "dormant" pain receptors, which have a higher threshold of excitability. China officinalis for pain of lower intensity,prone to periodic abatement and intensification. For Abrotanum in C7 dilution, the possibility of enhancing the action of the above components is shown. The action of these components is potentiated by Secale cornutum, which does not have pain syndrome in its indications for use, however, as we have shown, taken in C3 dilution enhances the action of Eupatorium perfoliatum, Bryonia alba, Rhus Toxicodendron, affecting the increase in blood flow in tissues and the delivery of nutrients to them, reducing peripheral sensitization and allowing to reduce the dilution (i.e. the dose) of other drugs in the proposed composition. In addition, these components reduce the release of tumor necrosis factors α (TNFα) and other proinflammatory cytokines by macrophages, which helps to reduce peripheral and central sensitization. Arnica montana in C3 dilution is able to relieve severe postoperative pain, pain from fractures, and in combination with Senecio aureus in C7 dilution allows to relieve aching,prolonged, irritating monotonous pain. Adding Stramonium to the composition in a C9 dilution allows to enhance its effect by influencing the mechanisms of pain chronization, removing its neurogenic component and pathological impulses in the pain center, increasing the body's sensitivity to other components. Aconitum napellus and Belladonna, taken in the specified dilutions, help to reduce agitation associated with pain syndrome, reduce anxiety, reduce the fear of death, also allowing the use of the actual analgesic components of the composition in a smaller dilution. The action is most likely associated with the inhibition of pain impulses by peripheral and descending nerve pathways. Ipecacuanha, in relation to pain, is usually used to treat migraine or pressing headaches, in combination with Nux vomica, taken in a C5 dilution, increase the sensitivity of nerve cells with mediators that help reduce pain syndrome. Gallicum acidum,Heloderma suspectum in C7 dilutions are used to increase blood flow, relieve vascular spasm, which promotes better penetration of other components of the composition to the source of pain. Mercurius solubilis is another homeopathic medicinal product that effectively affects acute, shooting, piercing pain, including cephalgia, reducing the activity of glutamine receptors and neurokinin-1 receptors, which leads to a decrease in cell excitability and, in combination with other drugs, potentiates the analgesic effect of the composition. The specified dilutions of each component of the composition (dosages) were selected as a result of multiple experimental studies, during which a comparison was made of the effectiveness of compositions containing the active components of the composition in various dilutions in the treatment of pain. The result of these experiments was the use of the components of the composition in equal parts in the following dilutions: Eupatorium perfoliatum in D3 dilution; China officinalis,Secale cornutum, Arnica montana in C3 dilution; Rhus toxicodendron in C4 dilution; Aconitum napellus, Belladonna, Bryonia alba, Ipecacuanha, Nux vomica in C5 dilution; Mercurius solubilis in C6 dilution; Abrotanum, Gallicum acidum, Heloderma suspectum, Senecio aureus in C7 dilution; Stramonium in C9 dilution. As part of the above-mentioned experimental studies, various modes and routes of administration of the proposed composition, methods for selecting or calculating an individual single dose were also tested. As a result, it was found that the greatest effectiveness of the composition in reducing pain is achieved with its oral use in an individual single dose with a frequency of administration on the first day of no more than 8 times, on the second and subsequent days - no more than 4 times. In this case, the individual single dose is determined by summing up the minimum single doses of the composition that contribute to the subjective sensation of pain reduction, and the minimum single dose,with which to start taking the composition is 1 drop or granule of the composition dissolved in 15 ml of water, based on every 10 kg of the patient's weight. The minimum single dose is taken every 15 minutes. Thus, the proposed composition is capable of influencing all mechanisms of pain syndrome development, which contributes to a significant reduction in pain regardless of the causes, localization and severity of the pain syndrome, i.e. increasing the effectiveness of pain treatment. The method for producing compositions according to the claimed invention: First, homeopathic tinctures of each component are prepared separately. The homeopathic tincture is prepared from trituration in the case of insoluble raw materials and from liquid form when using soluble raw materials. Next, homeopathic tinctures of single-component agents are potentiated (diluted) so that their degree of dilution is one step lower,than in the medicinal prescription. To prepare a homeopathic mixture, tinctures of single-component preparations are taken in equal proportions and mixed in a solvent of the specified volume or applied to an inert carrier (for example, granulated sugar). This preparation option is regulated by paragraph 106(b) of the Order of the Ministry of Health of the Russian Federation dated May 22, 2023 N 249n "On approval of the rules for the manufacture and dispensing of medicinal products for medical use by pharmacy organizations licensed for pharmaceutical activity." An additional advantage of these compositions is the ease of their manufacture. The compositions according to the invention can be manufactured by any pharmacy that has a homeopathic production department, since only registered single-component homeopathic medicines are used in the manufacture,and the manufacturing method complies with the generally accepted regulations for the manufacture of complex homeopathic preparations for in-house pharmacy production. The manufacture of compositions according to the invention is regulated by current legislation and regulatory documents ("Collection of Pharmacopoeial Articles on Homeopathy" edited by Corresponding Member of the Academy of Medical Sciences, Professor R. U. Khabriyev, Scientific Center for Expertise of Medical Products. Federal Service for Surveillance in Healthcare and Social Development. Moscow, 2005, pp. 3-41). The target additives used in the manufacture of compositions may be purified water, ethyl alcohol of various concentrations, glycerin, lactose, vegetable oils, petroleum jelly, lanolin, cocoa butter, etc. (I.I. Krasnyuk, G.V. Mikhailova. Pharmaceutical homeopathy. Ed. by N.A. Zamarenov, M., Academy, 2005) and allow to obtain compositions in different medicinal forms: alcohol drops – recommended for longer storage and for patients,suffering from diabetes; water drops - have the shortest shelf life and are recommended for rinsing the mucous membranes of the eyes, nose and for infants; rubbing (opodeldoc) - recommended for local use with the integrity of the skin to enhance the effect of action by increasing local blood supply; granules - are recommended as the most convenient form of application, but are contraindicated for patients suffering from diabetes; ointment / gel / oil - recommended for a longer method of local action and for the formation of a protective film on the surface of the skin or mucous membranes; suppositories - recommended in cases of difficult sublingual administration of the indicated composition (for example, infants or elderly patients) and to enhance the local effect with the corresponding localization of the pain syndrome. In special cases of the invention, the administration of the above composition is supplemented by the use of compositions,intended for use in the presence of a specific disease and / or condition that contributes to the occurrence of or is accompanied by pain syndrome. Additional compositions can be used in any form: alcohol drops, water drops, rubbing, granules, ointment / gel / oil, rectal or vaginal suppositories, while the main composition is used orally in the form of granules or drops diluted in water (to determine an individual single dose). The use of "additional" compositions selected depending on the disease or condition that contributed to the development of pain syndrome or accompanying pain, allows for faster relief of pain syndrome in each specific case, influencing either the acceleration of regeneration or the reduction of the inflammatory process and, in particular, the enhancement of the analgesic effect of the "main" composition. The technical result is an increase in the effectiveness of pain treatment,objectively manifested by a significant reduction in pain sensations that occurs in the shortest possible time after the start of treatment - is achieved through the use of a pharmaceutical composition, the components of which, taken in an effective amount to exhibit their properties, affect all known mechanisms of pain, potentiating the action of each other, and also due to the fact that the composition is used in an individually selected dose and with a regimen that does not allow so-called "pain breakthroughs". To assess the effectiveness of the proposed method, the following study was conducted from 2020 to 2023: All patient requests were recorded who had complaints about the presence of pain syndrome, regardless of the causes that caused it, localization,pain intensity. A total of 1,438 visits were recorded over less than 3 years. The intensity of the pain syndrome was assessed in accordance with clinical guidelines for pain treatment using the VAS (visual analogue scale) in millimetres: no pain: 0-4 mm; mild pain: 5-44 mm; moderate pain: 45-74 mm; severe pain: 75-100 mm. A 30% decrease in pain intensity is considered clinically significant; changes greater than 50% according to the VAS are significant; changes greater than 20 mm in severe pain syndrome are also considered significant. Depending on the severity of the pain syndrome, all patients were divided into three groups according to the degree of pain intensity in mm according to the VAS scale. The first group included 658 people, the second 453, the third 327. Each group was divided into 2 equal subgroups depending on the treatment received. In group I, II, III, subgroup A received treatment in accordance with the method,selected as the closest analogue of the invention; subgroup B - in accordance with the proposed method. Thus, in subgroup B, patients orally administered a pharmaceutical composition containing Eupatorium perfoliatum taken in equal amounts in a dilution of D3; China officinalis, Secale cornutum, Arnica montana in a dilution of C3; Rhus toxicodendron in a dilution of C4; Aconitum napellus, Belladonna, Bryonia alba, Ipecacuanha, Nux vomica in a dilution of C5; Mercurius solubilis in a dilution of C6; Abrotanum, Gallicum acidum, Heloderma suspectum, Senecio aureus in a dilution of C7; Stramonium in a dilution of C9. The administration was started with a minimum single dose of 1 drop or granule of the composition dissolved in 15 ml of water per 10 kg of the patient's weight; the minimum single dose was taken every 15 minutes. The individual single dose was determined by summing the minimum single doses of the composition,contributing to the subjective feeling of pain reduction. The composition was taken in an individual single dose with a frequency of administration on the first day of no more than 8 times, on the second and subsequent days - no more than 4 times. The duration of treatment was determined by the duration of the pain syndrome. The intensity of the pain syndrome according to the VAS scale daily before and daily during treatment. A comparison of treatment methods showed the following results: Table 1 - Severity of pain syndrome during treatment, in mm (average results per subgroup are given), The conducted study demonstrated a clinically significant reduction in pain (more than 30%) after the first day of treatment in subgroups IB, IIB, while the reduction in pain syndrome after the first day of treatment in subgroups IA and IIA did not exceed 7%. Moreover, in subgroup IB, at the end of the first day of treatment, a reduction in pain syndrome of more than 50% was recorded. In the group with severe pain syndrome, a significant reduction in pain was achieved on the 5th day of treatment when using the prototype of the proposed method and on the 3rd day when using the claimed solution. The obtained data indicate an increase in the effectiveness of pain treatment, objectively manifested by a significant reduction in pain sensations, occurring shortly after the start of treatment.

Claims

FORMULA 1. A method for treating pain, comprising oral administration of a pharmaceutical composition; administration begins with a minimum single dose of 1 drop or granule of the composition dissolved in 15 ml of water per 10 kg of the patient's weight; the minimum single dose is taken every 15 minutes; an individual single dose is determined by summing up the minimum single doses of the composition that contributed to the subjective feeling of pain reduction; the composition is taken in an individual single dose with a frequency of administration on the first day of no more than 8 times, on the second and subsequent days - no more than 4 times, wherein the pharmaceutical composition contains Eupatorium perfoliatum taken in D3 dilution; China officinalis, Secale cornutum, Arnica montana in C3 dilution; Rhus toxicodendron in C4 dilution; Aconitum napellus, Belladonna, Bryonia alba, Ipecacuanha, Nux vomica in C5 dilution; Mercurius solubilis in C6 dilution;Abrotanum, Gallicum acidum, Heloderma suspectum, Senecio aureus in C7 dilution; Stramonium in C9 dilution.

2. The method for treating pain according to claim 1, further comprising the step of determining the disease or condition that contributed to the occurrence of pain or is accompanied by pain, and using at least one additional pharmaceutical composition in a dosage form selected from the group: drops, rubbing, granules, ointment, gel, oil, suppositories, injection solutions.

3. The method for treating pain according to claim 2, consisting in the fact that in the event of pain occurring against the background of rhinitis and / or sinusitis, additionally using a pharmaceutical composition of Hydrastis canadensis taken in equal amounts in D4 dilution; Allium sulpha in D6 dilution; Dulcamara, Gelsemium sempervirens, Kalium bichromicum, Pulsatilla pratensis, Sabadilla, Sticta pulmonatia in C3 dilution; Aralia racemose in C5 dilution;Arsenicum album in C6 dilution.

4. The method for treating pain according to item 2, consisting in the fact that in the event of pain arising against the background of acute tonsillitis and / or pharyngitis, a composition is used of Eucalyptus globulus in D3 dilution; Lycopodium clavatum, Phytolacca decandra in C3 dilution; Barium carbonicum, Hepar sulfur in C5 dilution; Apis mellifica, Lachesis mutus in C6 dilution, taken in equal quantities.

5. The method for treating pain according to claim 2, which consists in that in the event of pain arising due to laryngitis, a composition is used of equal amounts of Arum triphyllum, Selenium metallicum in a C3 dilution; Ailanthus glandulosa in a C4 dilution; Argentum nitricum, Cuprum metallicum, Phosphorus in a C5 dilution; Agaricus muscarius, Magnesium muriaticum, Populus candicans in a C6 dilution; Carbo vegetabilis in a C8 dilution.

6. The method for treating pain according to claim 2, which consists in that in the event of pain arising due to chronic tonsillitis and / or chronic sinusitis, a composition is used of equal amounts of Thuja occidentalis in a D3 dilution; Arum triphyllum, Spigelia anthelmia in a C3 dilution; Agraphis nutans in a C4 dilution; Aurum metallicum, Baryta muriatica, Teucrium marum verum in C5 dilution; Mezereum in C6 dilution; Silicea terra in C8 dilution; Calcarea phosphorica in C9 dilution.

7. The method of treating pain according to item2, consisting in that in case of pain arising due to acute otitis and / or eustachitis, a composition is used of equal amounts of Plantago major in a dilution of D3; Cactus grandifloras in a dilution of D6; Camphor in a dilution of C2; Capsicum annuum in a dilution of C3; Manganum aceticum in a dilution of C4; Chamomilla recutita, Petroleum in a dilution of C5; Ferrum phosphoricum in a dilution of C6.

8. The method for treating pain according to claim 2, consisting in that in case of pain arising due to bronchitis and / or pneumonia, a composition is used of equal amounts of Arundo mauritanica in a dilution of D3; Rumex crispus, Sanguinaria canadensis, Spongia tosta, Drosera in a dilution of C3; Ambra grisea, Bromium in a dilution of C4; Causticum, Hyoscyamus niger in C5 dilution; Eupatorium perfoliatum, Antimonium tartaricum in C6 dilution; Phosphorus in C7 dilution.

9. The method of treating pain according to item2, which consists in the fact that in the case of a combination of pain with a cough, a composition is used from Drosera, Sanguinaria canadensis, Spongia tosta, Rumex crispus taken in equal quantities in a C3 dilution; Ambra grisea, Bromium in a C4 dilution; Causticum, Hyoscyamus niger in a C5 dilution; Antimonium tartaricum in a C6 dilution; Phosphorus in a C7 dilution; Sticta pulmonatia in a C12 dilution.

10. The method for treating pain according to paragraph 2, which consists in the fact that in the case of pain arising against the background of a bruise and / or sprain and / or bone fracture, it is used. a composition of equal amounts of Arnica montana in a dilution of D2; Bellis perennis in a dilution of D6; Rhus Toxicodendron, Ruta graveolens, Symphytum in a dilution of C3; Ledum palustre in a dilution of C4; Hypericum perforatum in a dilution of C5; Bryonia alba in a dilution of C6; Apis mellifica in a dilution of C7; Lachesis mutus in a dilution of C8; Calcarea phosphorica in a dilution of C9.

11. The method for treating pain according to claim 2, consisting in the fact that in the event of pain arising due to thermal or chemical damage to the skin, a composition is used of equal amounts of Calendula officinalis in a dilution of D2; Hamamelis virginica in a dilution of D3; Urtica urens in a dilution of D6; Cantharis vesicatoria in a dilution of C3; Causticum, Thuja occidentalis in C5 dilution; Apis mellifica, Arsenicum album, Hepar sulfur C6.

12. Method of treating pain according to item2, consisting in that in case of pain arising due to conjunctivitis, a composition is used of equal amounts of Euphrasia officinalis in a dilution of D3; Ranunculus bulbosus in a dilution of C2; Agaricus muscarius, Arundo mauritanica, Clematis erecta in a dilution of C3; Argentum nitricum in a dilution of C5; Natrium muriaticum in a dilution of C6.

13. The method for treating pain according to claim 2, consisting in that in case of pain arising due to a hordeolum or chalazion, a composition is used of equal amounts of Platanus occidentalis in a dilution of D3; Badiaga in a dilution of C2; Thuja occidentalis in a dilution of C3; Staphisagria in a dilution of C4; Hepar sulfur in a dilution of C5; Pulsatilla pratensis in a dilution of C6; Conium maculatum in C8 dilution.

14. Method of treating pain according to item2, consisting in that in case of pain arising due to pulpitis or alveolitis, a composition is used of equal amounts of Plantago major in a dilution of D3, Aconitum napellus, Hypericum perforatum in a dilution of C3; Chamomilla in a dilution of C5, Pulsatilla pratensis in a dilution of C8; Mercurius solubilis in a dilution of C9; Hepar sulfur in a dilution of C12.

15. The method for treating pain according to claim 2, consisting in that in case of pain arising due to arthropathy, a composition is used of equal amounts of Harpagophytum procumbens in a dilution of D3; Colchicum autumnale in a dilution of D4; Benzoicum acidum, Ledum palustre in a dilution of C3; Antimonium crudum, Causticum, Strontium carbonicum in a dilution of C4; Bambusa arundinacea, Lycopodium clavatum in C5 dilution, Calcarea carbonica, Aranea diadema in C6 dilution.

16. The method for treating pain according to claim 2, which consists in the fact that in the event of pain arising against the background of cardiomyopathy, a composition is used from Crataegus oxyacantha taken in equal amounts in dilution D1; Convallaria majalis in dilution C3; Digitalis purpurea in dilution C4; Laurocerasus in dilution C5; Latrodectus mactans, Naja tripudians in dilution C6; Kalium carbonicum in dilution C7; Moschus in dilution C9; Lilium lancifolium in dilution C12.

17. The method for treating pain according to claim2, consisting in that in case of pain arising due to cholecystitis, or cholangitis and / or biliary dyskinesia, or hepatitis, a composition is used of equal amounts of Myrica cerifera, Leptandra virginica in dilution D2; Dioscorea villosa in dilution D3; Chelidonium majus in dilution D6; Carduus marianus, Lycopodium clavatum in dilution C3; Ptelea trifolita, Taraxacum officinales in dilution C4, Chamomilla recutita, Natrium sulfuricum in dilution C5; Magnesia muriatica in dilution C6.

18. The method for treating pain according to claim 2, consisting in that in case of pain arising due to hemorrhoids and / or anal fissure, a composition is used of equal amounts of Aesculus hippocastanum in dilution D3; Ratanhia in dilution D5; Collinsonia сanadensis, Hamamelis virginica, Paeonia officinalis in dilution C3; Nitricum acidum in dilution C4; Calcarea fluorica in dilution C5; Vipera berus in dilution C6.

19. The method for treating pain according to item2, which consists in that in case of pain arising due to neuralgia or neuritis, a composition is used of equal amounts of Chelidonium majus in dilution D3; Verbascum Thapsus, Xantolylum fraxinfeum, Plantago major in dilution C3, Lepidium bonariensa in dilution C5; Cinnabaris, Dulcamara in dilution C6; Asa foetida in dilution C7; Cedron in dilution C8; Ignatia amara in dilution C9; Platinum metallicum in dilution C12.

20. The method for treating pain according to claim 2, which consists in that in case of pain arising due to teething, a composition is used of equal amounts of Rheum palmatum in dilution C3; Kreosotum in dilution C4; Phytolacca decandra in dilution C5; Chamomilla recutita in dilution C6; Kalium bromatum in C7 dilution; Cypripedium pubescens in C8 dilution; Belladonna, Calcarea carbonica in C9 dilution.

21. The method of treating pain according to item2, which consists in the fact that in the event of pain arising against the background of adhesive processes in the abdominal cavity and / or pelvic cavity,. a composition of equal amounts of Thiosinaminum in a dilution of D4; Fluoricum acidum, Ranunculus bulbosus in a dilution of C3; Nitricum acidum in a dilution of C4; Graphites in a dilution of C5; Silicea terra in a dilution of C6; Causticum in a dilution of C7; Iodium in a dilution of C9 is used.

22. The method for treating pain according to claim 2, consisting in the fact that in the event of pain occurring against the background of premenstrual syndrome, a composition of equal amounts of Agnus castus in a dilution of D4; Murex purpurea in a dilution of C3; Cimicifuga racemose, Kalium carbonicum in a dilution of C6; Calcarea carbonica in a dilution of C7; Natrium muriaticum, Pulsatilla pratensis, Conium maculatum in a dilution of C8; Chamomilla recutita in a dilution of C9 is used.

23. The method for treating pain according to claim2, consisting in that in case of pain arising due to glomerulonephritis, a composition is used of equal amounts of Solidago virgaurea, Eucalyptus globules in a C2 dilution; Apis mellifica, Uva ursi in a C3 dilution; Arsenicum album, Brachyglottis repens in a C4 dilution; Serum anguillae in a C5 dilution; Terebinthinae oleum in a C6 dilution; Mercurius corrosives in a C7 dilution.

24. The method for treating pain according to claim 2, consisting in that in case of pain arising due to pyelonephritis, a composition is used of equal amounts of Belladonna, Benzoicum acidum in a C3 dilution; Eupatorium perfoliatum in a C4 dilution; Sarsaparilla officinalis in a C5 dilution; Lycopodium clavatum in a C6 dilution; Apis mellifica in C7 dilution; Colchicum autumnale in C8 dilution; Hepar sulfur in C9 dilution.

25. The method of treating pain according to item2, which consists in that in case of pain arising due to urethritis or cystitis, a composition is used of equal amounts of Nitricum acidum, Pareira brava in a dilution of D6; Petroselinum sativum, Copaiva officinalis in a dilution of C3; Cantharis vesicatoria, Cubeba in a dilution of C4; Chimaphila umbellate in a dilution of C5; Doryphora decemlineata in a dilution of C7; Sepia officinalis in a dilution of C9.

26. The method for treating pain according to claim 2, which consists in that in case of pain arising due to urolithiasis, a composition is used of equal amounts of Coccus cacti in a dilution of C3; Pareira brava in a dilution of C4; Arnica montana, Calcarea carbonica, Chamomilla recutita, Colocynthis in a dilution of C5; Berberis vulgaris in a C6 dilution; Ocimum canum, Plumbum metallicum in a C6 dilution.

27. The method for treating pain according to claim 2, consisting in the fact that in the case of pain arising against the background of herpetic eruptions, a composition is used from Rhus toxicodendron taken in equal amounts in a D3 dilution; Cantharis vesicatoria in a D4 dilution; Sepia officinalis in a D5 dilution; Ranunculus bulbosus, Sarsaparilla in a C3 dilution; Thuja occidentalis in a C4 dilution; Alnus rubra in a C5 dilution; Arsenicum album, Dulcamara in a C6 dilution; Natrium muriaticum in a C7 dilution; Graphites in a C8 dilution, Hypericum perforatum in a C12 dilution.

28. The method for treating pain according to claim2, consisting in that in the case of a combination of pain with flatulence, a composition is used of equal amounts of Aethusa cynapium, Asa foetida, Dioscorea villosa in a C3 dilution; Carbo vegetabilis, Lycopodium clavatum, Chamomilla recutita in a C4 dilution; Anisum stellatum, Ambra grisea in a C5 dilution; Calcarea phosphorica in a C7 dilution; Argentum nitricum in a C9 dilution.

29. The method for treating pain according to claim 2, consisting in that in the case of pain occurring against the background of prostatitis, a composition is used of equal amounts of Cucurbita pepo in a D3 dilution; Clematis erecta in a C3 dilution; Euphrasia officinalis in a C4 dilution; Fabiana imbricate in a C5 dilution; Pulsatilla pratensis in a C6 dilution; Colchicum autumnale in C7 dilution; Dulcamara in C8 dilution; Hepar sulfur in C12 dilution.

30. The method of treating pain according to item2, consisting in that in case of pain arising due to prostate adenoma, a composition is used consisting of equal amounts of Aloe socotrina in a dilution of D4; Cicuta virosa in a dilution of D5; Sabal serrulata in a dilution of D6; Pareira brava, Allium sativum in a dilution of C3; Digitalis in a dilution of C4; Selenium metallicum in a dilution of C5; Conium maculatum in a dilution of C6; Iodium in a dilution of C7; Thuja occidentalis in a dilution of C8; Staphysagria in a dilution of C9.

31. The method for treating pain according to claim 2, consisting in that in case of pain arising due to inflammatory-necrotic processes in soft tissues, a composition is used consisting of equal amounts of Myrica cerifera in a dilution of D3; Calendula officinalis in a dilution of C4; Apis mellifica, Hamamelis virginica at C5 dilution; Lachesis mutus at C6 dilution; Bufo rana at C7 dilution; Hepar sulfur, Mercurius solubilis, Silicea terra at C8 dilution; Calcarea carbonica at C9 dilution.

32. The method for treating pain according to claim 2, which consists in that in the event of pain arising due to gastritis, a composition is used consisting of equal amounts of Anamirta cocculus in a C5 dilution; Antimonium crudum in a C6 dilution; Kalium carbonicum in a C7 dilution; Pulsatilla pratensis in a C8 dilution; Anacardium orientale in a C10 dilution; Argenutm nitricum in a C12 dilution.

33. The method for treating pain according to claim 2, which consists in that in the event of pain arising due to esophagitis, a composition is used consisting of equal amounts of Quassia amara in a D3 dilution; Cascarilla in a C2 dilution; Zingiber officinale in a C3 dilution; Kreosotum in a C4 dilution; Niccolum metallicum in a C5 dilution; Natrium carbonicum in a C6 dilution; Robinia pseudacacia in a C7 dilution.

34. The method of treating pain according to paragraph.2, consisting in that in case of pain arising due to gastric ulcer and / or duodenal ulcer, a composition is used consisting of equal amounts of Robinia in a C3 dilution; Manganum aceticum, Sulfuricum acidum in a C5 dilution, Ammonium muriaticum in a C6 dilution; Causticum in a C8 dilution.

35. The method for treating pain according to claim 2, consisting in that in case of pain arising due to damage to the integrity of the skin due to hyperkeratosis, a composition is used consisting of equal amounts of Arum triphyllum in a D6 dilution; Petroleum in a D9 dilution; Cundurango in a C3 dilution; Graphites in a C4 dilution; Antimonium crudum, Arsenicum album, Natrium muriaticum, Nitricum acidum in a C5 dilution; Alnus rubra, Mercurius solubilis in a C6 dilution; Lycopodium clavatum in C8 dilution.

36. Method of treating pain according to item2, consisting in that in case of pain arising against the background of myositis, a composition is used of equal amounts of Arnica montana, Rhus Toxicodendron, Ruta graveolens in a dilution of D3; Eupatorium perfoliatum, Ledum palustre in a dilution of D4; Bryonia alba in a dilution of D5; Hypericum perforatum in a dilution of D6; Formicicum acidum in a dilution of C3; Magnesium phosphoricum in a dilution of C7.

37. The method for treating pain according to claim 2, consisting in that in case of pain arising against the background of varicose veins of the lower extremities, a composition is used of equal amounts of Aesculus hippocastanum in a dilution of D3; Hamamelis virginiana in a dilution of D4; Arnica montana in a dilution of D5; Ruta graveolens, Lycopodium clavatum, Pulsatilla pratensis, Rhus toxicodendron in C3 dilution;. Causticum in a C5 dilution; Vipera berus, Ferrum metallicum in a C6 dilution; Fluoricum acidum in a C7 dilution; Zincum metallicum in a C8 dilution.

38. The method for treating pain according to claim 2, consisting in that in the event of pain arising against the background of erosive skin and / or mucous membrane lesions, a composition is used of equal amounts of Alnus rubra in a C3 dilution; Phytolacca decandra in a C4 dilution; Thuja occidentalis in a C5 dilution; Argentum metallicum, Sulfuricum acidum in a C6 dilution; Mercurius iodatus ruber in a C7 dilution; Carbolicum acidum in a C9 dilution.

39. The method for treating pain according to claim 2, consisting in that in the event of pain arising against the background of caries, a composition is used of equal amounts of Plantago major in a C3 dilution; Mezereum in a C4 dilution; Thuja occidentalis in C5 dilution; Kreosotum in C6 dilution; Fluoricum acidum in C7 dilution; Calcarea fluorica in C8 dilution; Staphysagria in C9 dilution.

40. The method of treating pain according to item2, consisting in that in case of pain arising against the background of muscle spasms and / or cramps, a composition is used of equal amounts of Colocynthis in dilution D3; Passiflora incarnata in dilution C2; Anamirta cocculus in dilution C3; Caulophyllum thalictroides in dilution C4; Magnesium phosphoricum in dilution C5; Agaricus muscarius in dilution C6; Gelsemium in dilution C7.

41. The method for treating pain according to claim 2, consisting in that in case of pain arising against the background of pancreatitis, a composition is used of equal amounts of Acidum silicicum in dilution D9; Momordica balsamina in dilution C2; Iris versicolor in dilution C3; Spongia tosta in dilution C4; Phosphorus in dilution C5; Iodium C6; Conium maculatum in dilution C7.

42. Method of treating pain according to item2, which consists in the fact that in the event of pain arising due to periodontosis, a composition is used of equal amounts of Arnica montana in a dilution of D3; Cistus canadensis, Kreosotum in a dilution of C3; Causticum, Fluoricum acidum, Hecla lava in a dilution of C4; Carbo vegetabilis, Staphisagria in a dilution of C5; Calcarea carbonica, Thuja occidentalis, Phosphorus in a dilution of C6; Plumbum metallicum in a dilution of C7; Mercurius solubilis in a dilution of C9.

43. The method for treating pain according to claim 2, which consists in the fact that in the event of pain arising due to ascites, a composition of equal amounts of Squilla is used. maritima in a dilution of D4; Helleborus niger in a dilution of C3; Apocynum cannabinum in a dilution of C4; Spigelia anthelmia in a dilution of C5; Ammonium carbonicum in a dilution of C6; Apis mellifica in a dilution of C9; Mercurius sulfuricus in a dilution of C10.

44. The method for treating pain according to claim 2, consisting in the fact that in the event of pain occurring against the background of metrorrhagia, a composition is used from Erigeron canadense in a dilution of D2; Sedum telephium in a dilution of D3; Ustilago maydis in a dilution of D4; Crocus sativus in a dilution of C2; Cinnamomum ceylanicum in a dilution of C3; Erodium cicutarium in a dilution of C4; Millefolium in a dilution of C5; Kalium ferrocyanatum in a dilution of C6; Phosphorus in a dilution of C7, taken in equal amounts.

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