Methods and apparatus for repairing heart valves

The catheter-based approximation and securing of chordae tendineae address heart valve regurgitation by enhancing leaflet coaptation, offering a less invasive solution to improve heart valve function.

WO2025160526A1 Publication Date: 2025-07-31BIANCUCCI BRIAN
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Patent Information

Application Number
PCT/US2025/013142
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-01-27
Filing Date
2025-01-27
Publication Date
2025-07-31

AI Technical Summary

Technical Problem

Heart valve regurgitation due to tethering of chordae tendineae, which prevents proper leaflet coaptation, is not effectively addressed by existing invasive and less invasive treatments.

Method used

A method and system involving a catheter-based approach to approximate and secure chordae tendineae attaching to opposing heart valve leaflets, using a grasper and fastener or energy source to reduce the distance between them and maintain closure, thereby enhancing leaflet coaptation.

Benefits of technology

The method and system effectively reduce or eliminate heart valve regurgitation by improving leaflet coaptation, providing a less invasive and more precise treatment for heart valve dysfunction.

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Abstract

A method for treating a patient includes delivering a distal portion of an elongate medical device into a ventricle of a beating closed heart of a subject via a primary skin opening and a secondary puncture, utilizing the distal portion of the elongate medical device to engage a plurality of chordae tendineae extending from a first papillary muscle within the ventricle, at least a first one of the plurality of chordae tendineae attached to a first leaflet of an atrioventricular valve located between the ventricle and an adjacent atrium, and at least a second one of the plurality of chordae tendineae attached to a second leaflet of the atrioventricular valve, approximating the engaged plurality of chordae tendineae to increase an amount of closure possible between the first leaflet and the second leaflet, and locking the plurality of chordae tendineae in their approximated condition.
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