Pharmaceutical chlorine dioxide antimicrobial liquid agent, preparation method therefor, and use thereof
By preparing a high-purity chlorine dioxide antimicrobial liquid, the stability and impurity problems of oxidative chlorine dioxide disinfectant and sterilizer were solved, providing a high-concentration, high-purity, and stable pharmaceutical chlorine dioxide solution suitable for broad-spectrum antimicrobial infection and oxidative anticancer treatment, thus achieving the stability and bactericidal effect of pharmaceutical chlorine dioxide.
Patent Information
- Application Number
- PCT/CN2025/086789
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2024-04-09
- Filing Date
- 2025-04-02
- Publication Date
- 2025-10-16
AI Technical Summary
Existing oxidative chlorine dioxide disinfectants suffer from poor stability and high impurity content, which affects their application. Furthermore, they cannot meet the requirements for high purity and low acidity in special applications, thus limiting their development in pharmaceutical antimicrobial infection control and oxidative anticancer drugs.
By preparing a pharmaceutical-grade chlorine dioxide antimicrobial liquid, high-purity chlorine dioxide gas is injected into deionized water, and the reaction vessel speed and flow rate are controlled to form stable hydrated chlorine dioxide, ensuring a concentration of 5000 mg/L to 10000 mg/L and a purity greater than 99%. It is stored under light-protected conditions to form ClOO(H2O)6-10 as a stabilizer, which is converted into a pure chlorine dioxide solution upon dilution.
The obtained pharmaceutical chlorine dioxide antimicrobial liquid has a high concentration and good stability, with a stable service period of more than one year. It has strong disinfection and sterilization capabilities and is suitable for human treatment or adjuvant treatment of diseases caused by pathogenic microorganisms. It can also be used as an exogenous oxide for anticancer treatment. Moreover, it does not require complicated equipment and is environmentally friendly and pollution-free.