Automatic cleaning solution proportioning method and apparatus, and biochemical analysis system

Abstract

An automatic cleaning solution proportioning method and apparatus, and a biochemical analysis system. The method comprises: on the basis of a signal of a first floating ball assembly (310) in a concentrated cleaning solution tank (300), setting a liquid pump (700) to be in a pumping-enabled state or a pumping-disabled state; when the liquid pump (700) is in the pumping-enabled state, determining, on the basis of a signal of a second floating ball assembly (420) in a diluent tank (400), whether to start the liquid pump (700); when the liquid pump (700) is in a running state, mixing water in a water tank (200) and a concentrated cleaning solution in the concentrated cleaning solution tank (300) and pumping same into the diluent tank (400); and when the liquid pump (700) is in the running state, turning off the liquid pump (700) on the basis of a signal of a third floating ball assembly (430) in the diluent tank (400). By means of the definition of the three floating ball assemblies cooperating with the pumping-enabled or pumping-disabled state of the liquid pump (700), the method has the advantage of there being fewer components required to achieve a proportioning function, resulting in lower cost; moreover, the proportioning ratio is not affected by variations between instruments or components, thus ensuring that all instruments can prepare solutions of the same proportion by using the same parameters; in addition, automatic mixing is performed by means of the liquid pump (700), thereby ensuring the uniformity of the proportioned solution.

Description

Automatic cleaning liquid proportioning method, device and biochemical analysis system TECHNICAL FIELD

[0001] The present application relates to the field of biochemical analysis, in particular to an automatic cleaning liquid proportioning method, device and biochemical analysis system. BACKGROUND

[0002] Biochemical analyzers in the in vitro diagnostic products (IVD) industry are instruments that detect certain specific chemical components in body fluids through colorimetric methods, turbidimetric methods, etc. In order to ensure the cleaning effect of the cuvette, the instrument must be cleaned with cleaning liquid.

[0003] Because concentrated cleaning liquid is used, the instrument's automatic dilution function is used for dilution. Automatic dilution is achieved by mixing pure water and replaced concentrated cleaning liquid inside the instrument through a series of components in a specific ratio to achieve proportioning, avoiding manual operation and errors.

[0004] Specifically, the traditional proportioning system is responsible for water inlet through a diaphragm pump, and cleaning liquid addition through another diaphragm pump, and achieves proportioning and transmission through multiple barrels and electromagnetic valves; and the traditional proportioning system achieves quantitative addition of proportioning through a plunger pump; the traditional proportioning system also controls the proportioning ratio through the height of a float switch. This can cause the following problems:

[0005] 1. Too many components are used to achieve the function of proportioning, resulting in complex structure of the proportioning system and rising application cost;

[0006] 2. Quantitative addition of proportioning and height control of the float switch result in inability to freely set the proportioning ratio;

[0007] 3. The proportioning ratio is affected by differences in instruments and pumps, resulting in the need for separate calibration of the proportioning ratio and affecting analysis efficiency;

[0008] 4. The solution after proportioning is not uniform, which can cause some areas to have too high concentration and affect analysis results.

[0009] SUMMARY

[0010] Therefore, it is necessary to provide an automatic cleaning liquid proportioning method, device and biochemical analysis system.

[0011] In one embodiment, an automatic cleaning liquid proportioning method includes the steps of:

[0012] setting the liquid pump to a pumpable state or an unpumpable state according to a signal of a first float ball assembly in the concentrated cleaning liquid tank;

[0013] determining whether to start the liquid pump according to the signal of the second floating ball assembly in the dilution liquid tank when the liquid pump is in the startable state;

[0014] mixing the water in the water tank and the concentrated cleaning liquid in the concentrated cleaning liquid tank and pumping into the dilution liquid tank when the liquid pump is in the startable state;

[0015] closing the liquid pump according to the signal of the third floating ball assembly in the dilution liquid tank when the liquid pump is in the startable state.

[0016] The automatic cleaning liquid proportioning method has the advantages of fewer components required for realizing the proportioning function, lower cost, and the proportioning ratio being not affected by the differences of instruments or components, so that the same proportion of solution can be proportioned by all instruments using the same parameters, and the solution after proportioning is uniform.

[0017] In one of the embodiments, determining whether to supplement the concentrated cleaning liquid according to the signal of the first floating ball assembly in the concentrated cleaning liquid tank, and if yes, sending a signal to supplement the concentrated cleaning liquid and setting the liquid pump to the non-pumpable state, otherwise setting the liquid pump to the startable state.

[0018] determining whether to supplement the dilution cleaning liquid according to the signal of the second floating ball assembly in the dilution liquid tank when the liquid pump is in the startable state.

[0019] In one of the embodiments, setting the first switch valve to the openable state and the non-openable state according to the signal of the first floating ball assembly in the concentrated cleaning liquid tank; wherein the openable state of the first switch valve is associated with the startable state of the liquid pump, and the non-openable state of the first switch valve is associated with the non-pumpable state of the liquid pump.

[0020] delivering the water in the water tank and the concentrated cleaning liquid in the concentrated cleaning liquid tank to the liquid pump through the first switch valve when the liquid pump is in the startable state.

[0021] In one of the embodiments, determining whether to supplement the concentrated cleaning liquid according to the signal of the first floating ball assembly in the concentrated cleaning liquid tank, and if yes, sending a signal to supplement the concentrated cleaning liquid and setting the first switch valve to the non-openable state, otherwise setting the first switch valve to the openable state.

[0022] pre-starting the liquid pump and running for a first preset time according to the signal of the second floating ball assembly in the dilution liquid tank when the first switch valve is in the openable state.

[0023] The first switching valve is started to deliver the first liquid and run for a second preset time, then the first switching valve is switched to deliver the second liquid and run for a third preset time as a cycle; wherein the first liquid is one of water in the water tank and concentrated cleaning liquid in the concentrated cleaning liquid tank, and the second liquid is the other;

[0024] During the cycle, according to the signal of the third floating ball assembly in the dilution liquid tank, the first switching valve is closed after the current cycle is completed;

[0025] After the first switching valve is closed, the liquid pump is closed after a fourth preset time.

[0026] In one embodiment, the automatic cleaning liquid proportioning method further comprises the step of starting the second switching valve after the liquid pump is started and runs for a first preset time, and before the first switching valve is started and runs for a second preset time.

[0027] The second switching valve is closed after the first switching valve is closed, and the liquid pump is closed after a fourth preset time.

[0028] In one embodiment, an automatic cleaning liquid proportioning device comprises a water tank, a concentrated cleaning liquid tank, a dilution liquid tank, and a liquid pump;

[0029] The water tank and the concentrated cleaning liquid tank are respectively connected to the liquid pump through pipelines, and the liquid pump is connected to the dilution liquid tank through a pipeline;

[0030] The automatic cleaning liquid proportioning device is provided with a first floating ball assembly in the concentrated cleaning liquid tank, which is used to set the pumpable state and the non-pumpable state of the liquid pump according to the signal of the first floating ball assembly;

[0031] The automatic cleaning liquid proportioning device is provided with a second floating ball assembly and a third floating ball assembly in the dilution liquid tank, the second floating ball assembly and the third floating ball assembly are respectively connected to the liquid pump through lines, and the automatic cleaning liquid proportioning device is used to start the liquid pump according to the signal of the second floating ball assembly, and is also used to close the liquid pump according to the signal of the third floating ball assembly.

[0032] In one embodiment, the automatic cleaning liquid proportioning device further comprises a first switching valve, the water tank and the concentrated cleaning liquid tank are respectively connected to the first switching valve through pipelines, and the first switching valve is connected to the liquid pump through a pipeline;

[0033] The automatic cleaning liquid proportioning device is used to start the first switching valve and the liquid pump according to the signal of the second floating ball assembly, and is also used to close the first switching valve and the liquid pump according to the signal of the third floating ball assembly.

[0034] The first float ball assembly is used to set the first switch valve to an openable state and a non-openable state; wherein the openable state of the first switch valve is associated with the pumpable state of the liquid pump, and the non-openable state of the first switch valve is associated with the non-pumpable state of the liquid pump.

[0035] The liquid pump is used to pump the water in the water tank and the concentrated cleaning liquid in the concentrated cleaning liquid tank through the first switch valve in the starting state.

[0036] In one of the embodiments, the automatic cleaning liquid proportioning device further comprises a second switch valve, and the first switch valve and the dilution liquid tank are connected to the liquid pump through the second switch valve respectively by pipelines;

[0037] The second float ball assembly and the third float ball assembly are connected to the second switch valve by lines respectively, and the liquid pump and the first switch valve are connected to the second switch valve by lines respectively, the automatic cleaning liquid proportioning device is used to start the first switch valve, the second switch valve and the liquid pump according to the signal of the second float ball assembly, and is used to close the first switch valve, the second switch valve and the liquid pump according to the signal of the third float ball assembly.

[0038] In one of the embodiments, the liquid pump is a diaphragm pump.

[0039] Alternatively, the automatic cleaning liquid proportioning device is provided with a fourth float ball assembly in the water tank, and the openable state and the non-openable state of the first switch valve are set by the first float ball assembly and the fourth float ball assembly together; or,

[0040] The automatic cleaning liquid proportioning device further comprises an alarm, the alarm is connected to the first float ball assembly or the first switch valve, and the alarm is used to send a prompt signal when the liquid pump is in the non-pumpable state; or,

[0041] The first switch valve, the second switch valve and the liquid pump are linked together; or,

[0042] The automatic cleaning liquid proportioning device further comprises a controller, the controller is connected to the first switch valve, the second switch valve, the liquid pump, the first float ball assembly, the second float ball assembly and the third float ball assembly respectively, the first float ball assembly is connected to the first switch valve through the controller, and the second float ball assembly and the third float ball assembly are connected to the second switch valve and the liquid pump through lines respectively through the controller.

[0043] In one of the embodiments, a biochemical analysis system includes an analysis device and the automatic cleaning solution proportioning device of any of the embodiments, and the analysis device obtains diluent from the diluent tank of the automatic cleaning solution proportioning device. BRIEF DESCRIPTION OF DRAWINGS

[0044] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the drawings needed to be used in the embodiments or the prior art description will be briefly introduced. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative effort on the basis of these drawings.

[0045] Fig. 1 is a flowchart of an embodiment of the automatic cleaning solution proportioning method of the present application.

[0046] Fig. 2 is a structural schematic diagram of a first embodiment of the automatic cleaning solution proportioning device of the present application.

[0047] Fig. 3 is a structural schematic diagram of a second embodiment of the automatic cleaning solution proportioning device of the present application.

[0048] Fig. 4 is a structural schematic diagram of a third embodiment of the automatic cleaning solution proportioning device of the present application.

[0049] Fig. 5 is a structural schematic diagram of a fourth embodiment of the automatic cleaning solution proportioning device of the present application.

[0050] Fig. 6 is a structural schematic diagram of a fifth embodiment of the automatic cleaning solution proportioning device of the present application.

[0051] Fig. 7 is a structural schematic diagram of a sixth embodiment of the automatic cleaning solution proportioning device of the present application.

[0052] Reference signs: automatic cleaning solution proportioning device 100, water tank 200, fourth floating ball assembly 240, concentrated cleaning solution tank 300, first floating ball assembly 310, low proportioning 320, diluent tank 400, reserved position 410, second floating ball assembly 420, third floating ball assembly 430, first switching valve 500, second switching valve 600, liquid pump 700, circuit 800, first pipeline 810, second pipeline 820, third pipeline 830, fourth pipeline 840, fifth pipeline 850, alarm 900. DETAILED DESCRIPTION

[0053] In order to make the above objectives, features and advantages of the present application more clear and comprehensible, specific embodiments of the present application will be described below in detail with reference to the accompanying drawings. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present application. It will be apparent, however, to one skilled in the art that the present application can be practiced without using some or all of these specific details. In other instances, well known process steps have not been described in detail in order not to unnecessarily obscure the present application.

[0054] It is to be noted that when an element or layer is referred to as being "on" or "connected to" another element or layer, it can be directly on or connected to the other element or layer, or intervening elements or layers can be present. In contrast, when an element is referred to as being "directly on" or "directly connected to" another element, there are no intervening elements or layers present. The use of the term "connected" includes the presence of a wired or wireless connection.

[0055] In addition, the terms "first", "second", etc. are used herein only to describe various elements, and do not imply a relative importance or a specific order of the elements. Thus, features defined with "first", "second", etc. can explicitly or implicitly include at least one of the features. In the description of the present application, the meaning of "a plurality" is at least two, such as two, three, etc., unless otherwise specifically defined.

[0056] In the present application, unless otherwise explicitly specified and limited, "on", "under", and "below" of a first feature to a second feature can mean that the first feature is in direct contact with the second feature, or the first feature is in indirect contact with the second feature through an intermediate medium. Moreover, "above", "over", and "on top of" of a first feature to a second feature can mean that the first feature is directly above or obliquely above the second feature, or only means that the first feature is horizontally higher than the second feature. "Below", "under", and "underneath" of a first feature to a second feature can mean that the first feature is directly below or obliquely below the second feature, or only means that the first feature is horizontally lower than the second feature.

[0057] Unless otherwise defined, all technical and scientific terms used in the present application have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used in the description of the present application is for the purpose of describing particular embodiments only and is not intended to be limiting of the present application. The use of the terms "and / or" includes a combination of one or more of the associated listed items.

[0058] The application discloses an automatic cleaning liquid proportioning method, device and biochemical analysis system, and relates to the technical field of biochemical analysis. In one embodiment of the application, an automatic cleaning liquid proportioning method is shown in Figure 1, which comprises the following steps: according to the signal of a first floating ball assembly in a concentrated cleaning liquid tank, setting a liquid pump to a pumpable state or an unpumpable state; when the liquid pump is in the pumpable state, according to the signal of a second floating ball assembly in a dilute liquid tank, determining whether to start the liquid pump; when the liquid pump is in the starting state, pumping water in a water tank and concentrated cleaning liquid in the concentrated cleaning liquid tank into the dilute liquid tank; and when the liquid pump is in the starting state, according to the signal of a third floating ball assembly in the dilute liquid tank, closing the liquid pump. The automatic cleaning liquid proportioning method, by means of three floating ball assemblies cooperating with the pumpable state of the liquid pump, has the advantages of fewer components required for realizing the proportioning function and lower cost, the proportioning ratio is not affected by differences in instruments or components, the same parameters can be used for all instruments to proportion the same proportion of solution, and the proportioned solution is automatically mixed by the liquid pump, thereby ensuring the uniformity of the proportioned solution.

[0059] The automatic cleaning liquid proportioning method, device and biochemical analysis system will be described in detail below with reference to Figures 1 to 7. In each embodiment, the automatic cleaning liquid proportioning method can also be referred to as a cleaning liquid automatic proportioning method, and the automatic cleaning liquid proportioning device can also be referred to as a cleaning liquid automatic proportioning device.

[0060] In one of the embodiments, an automatic cleaning solution mixing method comprises the following steps: S10, setting a liquid pump 700 to a pumpable state or an unpumpable state according to a signal of a first float ball assembly 310 in a concentrated cleaning solution tank 300; S20, determining whether to start the liquid pump 700 according to a signal of a second float ball assembly 420 in a dilute cleaning solution tank 400 when the liquid pump 700 is in the pumpable state; S30, mixing water in a water tank 200 and concentrated cleaning solution in the concentrated cleaning solution tank 300 and pumping the mixture into the dilute cleaning solution tank 400 when the liquid pump 700 is in the starting state; and S40, closing the liquid pump 700 according to a signal of a third float ball assembly 430 in the dilute cleaning solution tank 400 when the liquid pump 700 is in the starting state. Before starting, the liquid pump 700 needs to be pre-judged. If it is in the unpumpable state, the liquid pump 700 cannot be started. If it is in the pumpable state, the liquid pump 700 can be started to mix water in the water tank 200 and concentrated cleaning solution in the concentrated cleaning solution tank 300 and pump the mixture into the dilute cleaning solution tank 400. The pumping process has completed the mixing of water and concentrated cleaning solution and the proportion control of the mixing. Moreover, through the three float ball assemblies, i.e., the first float ball assembly 310, the second float ball assembly 420 and the third float ball assembly 430, in combination with the pumpable state of the liquid pump 700, the number of components required to realize the mixing function is small, and the cost is low.

[0061] In the above embodiments, each float ball assembly is provided with a float ball and a corresponding structural member. The first float ball assembly 310 is a concentrated cleaning solution low liquid level float ball, the second float ball assembly 420 is a dilute cleaning solution low liquid level float ball, and the third float ball assembly 430 is a dilute cleaning solution high liquid level float ball. Those skilled in the art can understand that the above description of the first float ball assembly 310, the second float ball assembly 420 and the third float ball assembly 430 is only an example.

[0062] In order to facilitate automatic dilution, in one embodiment, according to the signal of the first floating ball assembly 310 in the concentrated cleaning solution tank 300, it is determined whether the concentrated cleaning solution needs to be supplemented. If yes, a signal is sent to require supplement of the concentrated cleaning solution, and the liquid pump 700 is set to be in a non-pumpable state. If no, the liquid pump 700 is set to be in a pumpable state. When the liquid pump 700 is in the pumpable state, according to the signal of the second floating ball assembly 420 in the dilution tank 400, it is determined whether the dilution cleaning solution needs to be supplemented. If yes, the liquid pump 700 is started. That is, before supplement of the dilution cleaning solution, it is necessary to determine whether the concentrated cleaning solution is available. If yes, the liquid pump 700 is started to pump water in the water tank 200 and the concentrated cleaning solution in the concentrated cleaning solution tank 300, so as to supplement the dilution cleaning solution in the dilution tank 400. In this way, it can be ensured that the analysis equipment such as an analyzer can obtain the dilution cleaning solution from the dilution tank 400, and it is beneficial to complete the analysis work in cooperation with the automatic assembly line.

[0063] In a specific implementation, two liquid pumps 700 can be used to pump water and concentrated cleaning solution respectively. However, in order to simplify the product structure, only one liquid pump 700 can be used to pump water and concentrated cleaning solution simultaneously. In one embodiment, according to the signal of the first floating ball assembly 310 in the concentrated cleaning solution tank 300, the first switching valve 500 is set to be in an openable state or a non-openable state. The openable state of the first switching valve 500 is associated with the pumpable state of the liquid pump 700, and the non-openable state of the first switching valve 500 is associated with the non-pumpable state of the liquid pump 700. When the liquid pump 700 is in a started state, water in the water tank 200 and concentrated cleaning solution in the concentrated cleaning solution tank 300 are respectively delivered to the liquid pump 700 through the first switching valve 500. For example, by controlling the on-off time ratio of the concentrated cleaning solution in the concentrated cleaning solution tank 300 and the water in the water tank 200 through the first switching valve 500, automatic cleaning solution proportioning is realized, that is, automatic cleaning solution proportioning is realized. For example, the first switching valve 500 outputs a first on-off time for the concentrated cleaning solution in the concentrated cleaning solution tank 300, and outputs a second on-off time for the water in the water tank 200. Under the condition that the pump pressure of the liquid pump 700 is the same, the ratio of the first on-off time to the second on-off time corresponds to the ratio of the cleaning solution proportioning. Such a design is beneficial to realize cleaning solution proportioning by controlling the simultaneous pumping of water and concentrated cleaning solution through the pipe selection or cut-off of the first switching valve 500. On the other hand, the water and the concentrated cleaning solution can be mixed during pipeline delivery and pumping, which is a double benefit. Moreover, compared with the traditional control mode, the number of components required to realize the proportioning function is small, and the cost is low.

[0064] The following continues to give a specific example, in which one embodiment, according to the signal of the first floating ball assembly 310 in the concentrated cleaning solution tank 300, it is determined whether to need to supplement the concentrated cleaning solution, yes, the signal of requiring to supplement the concentrated cleaning solution is sent, the first switching valve 500 is set to the state of being unable to open, otherwise the first switching valve 500 is set to the state of being able to open; in the state of the first switching valve 500 being able to open, according to the signal of the second floating ball assembly 420 in the dilution liquid tank 400, the liquid pump 700 is pre-started and runs for a first preset time; the first switching valve 500 is started to deliver the first liquid and runs for a second preset time, then the first switching valve 500 is switched to deliver the second liquid and runs for a third preset time, as a cycle; wherein the first liquid is one of the water in the water tank 200 and the concentrated cleaning solution in the concentrated cleaning solution tank 300, and the second liquid is the other of the water in the water tank 200 and the concentrated cleaning solution in the concentrated cleaning solution tank 300; in the cycle process, according to the signal of the third floating ball assembly 430 in the dilution liquid tank 400, after completing the current cycle, the first switching valve 500 is closed; after the first switching valve 500 is closed, the liquid pump 700 is closed after being delayed for a fourth preset time. Exemplarily, the first liquid is the water in the water tank 200, and the second liquid is the concentrated cleaning solution in the concentrated cleaning solution tank 300, in this embodiment, the ratio of the third preset time to the second preset time is the concentration ratio of the target dilution cleaning solution. Conversely, it is also possible. Such a design, the pre-starting of the liquid pump 700 and the running for the first preset time are beneficial to ensure the stable work of the liquid pump 700; and the design of the third preset time and the second preset time is easy to realize or adjust the automatic cleaning solution ratio; the design of the delay for the fourth preset time is beneficial to ensure the accuracy of the concentration of the dilution cleaning solution entering the dilution liquid tank 400. Moreover, such a design, the ratio of the ratio is not affected by the difference of instruments or components, and the same parameters can be used to ensure that all instruments use the same proportion of solution.

[0065] In order to improve the mixing effect, in one embodiment, after the pre-starting of the liquid pump 700 and running for a first preset time, and before the starting of the first switching valve 500 and running for a second preset time, the automatic cleaning liquid proportioning method further comprises the steps of: starting the second switching valve 600; closing the second switching valve 600 after closing the first switching valve 500, delaying for a fourth preset time, and closing the liquid pump 700. Exemplarily, the dilution liquid tank 400 is connected to the second switching valve 600 through a pipeline, and the starting of the second switching valve 600 comprises: starting the second switching valve 600 to transport the third liquid and running for a fifth preset time, and then switching the second switching valve 600 to transport the dilution cleaning liquid and running for a sixth preset time, as a mixing cycle; wherein the third liquid is the mixture of water and concentrated cleaning liquid, i.e. the liquid transported from the first switching valve 500, and the dilution cleaning liquid is the liquid in the dilution liquid tank 400. Such design can greatly improve the mixing uniformity of the automatic cleaning liquid, and further ensure the uniformity of the proportioned solution. Moreover, as known from the foregoing description, the automatic cleaning liquid proportioning method requires a small number of components for realizing the proportioning function, has a low cost, and the proportioning ratio is not affected by the differences of instruments or components, so that the same parameters can be used to ensure that the same proportion of solution is proportioned for all instruments. Moreover, through the design of the second switching valve 600, the automatic mixing effect is further improved, and the uniformity of the proportioned solution is ensured.

[0066] In combination with the automatic cleaning solution proportioning method, the specific structure design is exemplarily illustrated. In one of the embodiments, an automatic cleaning solution proportioning device 100 is shown in FIG. 2, which comprises a water tank 200, a concentrated cleaning solution tank 300, a diluent tank 400 and a liquid pump 700; the water tank 200 and the concentrated cleaning solution tank 300 are respectively connected to the liquid pump 700 through pipelines, and the liquid pump 700 is connected to the diluent tank 400 through a pipeline; the automatic cleaning solution proportioning device 100 is provided with a first floating ball assembly 310 in the concentrated cleaning solution tank 300, which is used to set the pumpable state and the non-pumpable state of the liquid pump 700 according to the signal of the first floating ball assembly 310; the automatic cleaning solution proportioning device 100 is provided with a second floating ball assembly 420 and a third floating ball assembly 430 in the diluent tank 400, the second floating ball assembly 420 and the third floating ball assembly 430 are respectively connected to the liquid pump 700 through a line 800, and the automatic cleaning solution proportioning device 100 is used to start the liquid pump 700 according to the signal of the second floating ball assembly 420, and is also used to close the liquid pump 700 according to the signal of the third floating ball assembly 430. It can be understood that the design concept of the automatic cleaning solution proportioning device 100 is the same as or similar to that of the automatic cleaning solution proportioning method, and the functions are the same or similar, so the automatic cleaning solution proportioning device 100 also has the related beneficial technical effects of the automatic cleaning solution proportioning method, which will not be repeated here. Moreover, those skilled in the art can understand that the automatic cleaning solution proportioning device 100 also comprises related pipeline connection structures, which will not be repeated here.

[0067] Exemplarily, the automatic cleaning solution proportioning method is realized based on the automatic cleaning solution proportioning device 100 of any one of the embodiments; or the automatic cleaning solution proportioning device 100 is realized by using the automatic cleaning solution proportioning method of any one of the embodiments; it can also be understood that when the automatic cleaning solution proportioning device 100 is applied, the related steps of the automatic cleaning solution proportioning method of any one of the embodiments can be used to realize, and when the automatic cleaning solution proportioning method is applied, the related structures of the automatic cleaning solution proportioning device 100 of any one of the embodiments can be used to realize.

[0068] In each embodiment, the liquid pump 700 is used to pump liquid, that is, the liquid pump 700 is a mechanical device for pumping liquid; as an example, the water in the water tank 200 and the concentrated cleaning solution in the concentrated cleaning solution tank 300 are mixed and pumped into the diluent tank 400 by the liquid pump 700; in one of the embodiments, the liquid pump 700 is a positive displacement pump, as an example, the liquid pump 700 is a diaphragm pump; in other embodiments, the liquid pump 700 can also be a centrifugal pump or a plunger pump, etc.

[0069] In one embodiment, as shown in FIG. 2, the concentrated cleaning solution in the concentrated cleaning solution tank 300 is in a full state, the first float ball assembly 310 in the concentrated cleaning solution tank 300 sends a concentrated cleaning solution full signal or a concentrated cleaning solution available signal, and the liquid pump 700 is set to a pumpable state; as an example, the first float ball assembly 310 sends a concentrated cleaning solution full signal or a concentrated cleaning solution available signal to the controller, and the liquid pump 700 is set to a pumpable state by the controller. In contrast, as shown in FIG. 3, the concentrated cleaning solution in the concentrated cleaning solution tank 300 is in an empty state, the first float ball assembly 310 in the concentrated cleaning solution tank 300 sends a concentrated cleaning solution empty signal or a concentrated cleaning solution unavailable signal, and the liquid pump 700 is set to a non-pumpable state; as an example, the first float ball assembly 310 sends a concentrated cleaning solution empty signal or a concentrated cleaning solution unavailable signal to the controller, and the liquid pump 700 is set to a non-pumpable state by the controller. As an example, for an embodiment with the first switching valve 500, the first float ball assembly 310 sends a concentrated cleaning solution full signal or a concentrated cleaning solution available signal to the controller, and the liquid pump 700 is set to a pumpable state by the controller, and the first switching valve 500 is set to an openable state, that is, the openable state of the first switching valve 500 is associated with the pumpable state of the liquid pump 700. Similarly, the first float ball assembly 310 sends a concentrated cleaning solution empty signal or a concentrated cleaning solution unavailable signal to the controller, and the liquid pump 700 is set to a non-pumpable state by the controller, and the first switching valve 500 is set to a non-openable state, that is, the non-openable state of the first switching valve 500 is associated with the non-pumpable state of the liquid pump 700. As an example, for an embodiment with the second switching valve 600, the second switching valve 600 is set to an openable state and a non-openable state according to the signal of the first float ball assembly 310 in the concentrated cleaning solution tank 300; wherein the openable state of the second switching valve 600 is associated with the pumpable state of the liquid pump 700, and the non-openable state of the second switching valve 600 is associated with the non-pumpable state of the liquid pump 700; in this way, the liquid pump 700 is associated with the first switching valve 500 and the second switching valve 600, realizing the linkage of opening and closing, especially the delayed opening and closing, which is beneficial to obtaining an accurate automatic cleaning solution mixing result and a uniform diluted cleaning solution.

[0070] When the second float ball assembly 420 in the dilution tank 400 sends a signal to request replenishment of dilution cleaning solution, considering the volume of the dilution tank 400 and the concentration requirement of the dilution cleaning solution, the requirement of concentrated cleaning solution in the concentrated cleaning solution tank 300 for each automatic cleaning solution preparation is approximately similar. For example, in one embodiment, as shown in FIG. 4, the concentrated cleaning solution tank 300 is provided with a low position 320 according to the volume of the dilution tank 400 and the concentration requirement of the dilution cleaning solution. The first float ball assembly 310 or the fifth float ball assembly in the concentrated cleaning solution tank 300 sends a signal to request replenishment of concentrated cleaning solution when it is lowered to the low position 320. At this time, the liquid pump 700 does not need to be set to an un-pumpable state, and the signal to request replenishment of concentrated cleaning solution does not need to be sent when it is floated to the low position 320. For example, in the control judgment, generally the concentrated cleaning solution tank 300 is full or meets the requirement when the system is running, as shown in FIG. 5. Therefore, the first float ball assembly 310 or the fifth float ball assembly in the concentrated cleaning solution tank 300 sends a signal to request replenishment of concentrated cleaning solution when it reaches the low position 320 for the first time or odd times, and then after replenishment of concentrated cleaning solution, the first float ball assembly 310 or the fifth float ball assembly in the concentrated cleaning solution tank 300 does not need to send a signal to request replenishment of concentrated cleaning solution when it reaches the low position 320 for the second time or even times. For example, these signals can be sent to the controller first, and then forwarded to the liquid pump 700 and / or the first switching valve 500, etc. by the controller. For example, the concentrated cleaning solution in the concentrated cleaning solution tank 300 in the low position 320 is set according to the product of the maximum concentration of the dilution cleaning solution and the volume of the dilution tank 400, so that when the first float ball assembly 310 or the fifth float ball assembly in the concentrated cleaning solution tank 300 sends a signal to request replenishment of concentrated cleaning solution when it is lowered to the low position 320, it can also meet the requirement of supplying dilution cleaning solution once again; such design can realize seamless connection with automatic supply or manual supply, and meet the requirement of continuous production for automatic analysis.

[0071] In one of the embodiments, as shown in FIG. 2 and FIG. 3, the automatic cleaning solution proportioning device 100 further comprises a first switch valve 500, the water tank 200 and the concentrated cleaning solution tank 300 are connected to the first switch valve 500 through pipelines, and the first switch valve 500 is connected to the liquid pump 700 through a pipeline; the automatic cleaning solution proportioning device 100 is configured to start the first switch valve 500 and the liquid pump 700 according to the signal of the second floating ball assembly 420, and to close the first switch valve 500 and the liquid pump 700 according to the signal of the third floating ball assembly 430; the first floating ball assembly 310 is configured to set the first switch valve 500 to an openable state and a non-openable state; the openable state of the first switch valve 500 is associated with the pumpable state of the liquid pump 700, and the non-openable state of the first switch valve 500 is associated with the non-pumpable state of the liquid pump 700; the liquid pump 700 is configured to pump the water in the water tank 200 and the concentrated cleaning solution in the concentrated cleaning solution tank 300 through the first switch valve 500 in the starting state. As mentioned above, by controlling the switching and on-off of the first switch valve 500, the accuracy of automatic cleaning solution proportioning can be further ensured.

[0072] When the dilution tank 400 is almost full in the starting state of the liquid pump 700, the liquid pump 700 is closed according to the signal of the third floating ball assembly 430 in the dilution tank 400, and for the embodiment with the first switch valve 500, the first switch valve 500 can be closed at the same time or in sequence; similarly, for the embodiment with the second switch valve 600, the second switch valve 600 can be closed at the same time or in sequence. As an example, the first switch valve 500, the second switch valve 600 and the liquid pump 700 are linked; the second switch valve 600 can be started at the same time or in sequence when the liquid pump 700 is started, and / or the first switch valve 500 can be started at the same time or in sequence when the second switch valve 600 is started; vice versa.

[0073] In order to avoid the dilution cleaning solution overflowing the dilution tank 400, the dilution tank 400 is provided with a reserved position 410, when the third floating ball assembly 430 in the dilution tank 400 floats up to the reserved position 410, a closing signal is sent to close the liquid pump 700; as an example, the closing signal is sent to the controller to close the liquid pump 700 through the controller; and for the embodiment with the first switching valve 500, the first switching valve 500 can be closed at the same time or in sequence; similarly, for the embodiment with the second switching valve 600, the second switching valve 600 can be closed at the same time or in sequence. The third floating ball assembly 430 in the dilution tank 400 does not need to send a closing signal when it moves down to the reserved position 410. As an example, the remaining volume of the dilution tank 400 at the reserved position 410 is greater than or equal to the volume of one mixing cycle of the water in the water tank 200 and the concentrated cleaning solution in the concentrated cleaning solution tank 300, that is, one cycle is met, so that when the dilution cleaning solution obtained in the current cycle reaches the reserved position 410, the remaining volume of the dilution tank 400 at the reserved position 410 can accommodate the remaining water and concentrated cleaning solution to complete the current cycle. As an example, in the control judgment, the floating or moving state of the first floating ball assembly 310, the third floating ball assembly 430 or the fifth floating ball assembly can be determined by the conduction and disconnection of the two adjacent circuits above and below. Such design is beneficial to avoid overflow due to excessive pumping under the premise of ensuring the amount of dilution cleaning solution in the dilution tank 400 as much as possible.

[0074] In one of the embodiments, the automatic cleaning solution proportioning device 100 further comprises a second switching valve 600, the first switching valve 500 and the dilution tank 400 are connected to the liquid pump 700 through the second switching valve 600; the second floating ball assembly 420 and the third floating ball assembly 430 are connected to the second switching valve 600 through the line 800, and the second switching valve 600 is connected to the liquid pump 700 and the first switching valve 500 through the line 800, the automatic cleaning solution proportioning device 100 is used to start the first switching valve 500, the second switching valve 600 and the liquid pump 700 according to the signal of the second floating ball assembly 420, and is used to close the first switching valve 500, the second switching valve 600 and the liquid pump 700 according to the signal of the third floating ball assembly 430. As described above, by controlling the switching and on-off of the second switching valve 600, the uniformity of the dilution cleaning solution can be improved.

[0075] In view of the fact that the water in the water tank 200 can also be insufficient due to various factors, in one embodiment, as shown in FIG. 6, the automatic cleaning solution proportioning device 100 is provided with a fourth floating ball assembly 240 in the water tank 200, and the first switch valve 500 is set to an openable state or a non-openable state by the first floating ball assembly 310 and the fourth floating ball assembly 240. That is, the first switch valve 500 is set to an openable state or a non-openable state by the signal of the first floating ball assembly 310 and the signal of the fourth floating ball assembly 240. For example, according to the signal of the first floating ball assembly 310 in the concentrated cleaning solution tank 300, it is determined that the concentrated cleaning solution does not need to be supplemented into the concentrated cleaning solution tank 300, and according to the signal of the fourth floating ball assembly 240 in the water tank 200, it is determined that the water does not need to be supplemented into the water tank 200, and the first switch valve 500 is set to an openable state. If the concentrated cleaning solution needs to be supplemented into the concentrated cleaning solution tank 300 or the water needs to be supplemented into the water tank 200, the first switch valve 500 is set to a non-openable state. Such a design further ensures the accuracy of the concentration of the diluted cleaning solution obtained by automatic proportioning.

[0076] In order to facilitate the supplement of water in the water tank 200 and / or concentrated cleaning solution in the concentrated cleaning solution tank 300, in one embodiment, as shown in FIG. 7, the automatic cleaning solution proportioning device 100 further comprises an alarm 900 connected to the first floating ball assembly 310 or the first switch valve 500, and the alarm 900 is used to send a prompt signal when the liquid pump 700 is in a non-pumping state. The prompt signal includes but is not limited to sound, flashing light, or information, etc.

[0077] In order to facilitate effective control, the automatic cleaning solution proportioning device 100 further comprises a controller connected to the first switch valve 500, the second switch valve 600, the liquid pump 700, the first floating ball assembly 310, the second floating ball assembly 420, and the third floating ball assembly 430. The first floating ball assembly 310 is connected to the first switch valve 500 through the controller, and the second floating ball assembly 420 and the third floating ball assembly 430 are connected to the second switch valve 600 and the liquid pump 700 through the controller through the line 800. For example, for the embodiment with the fourth floating ball assembly 240, the controller is also connected to the fourth floating ball assembly 240. The implementation of the controller is not limited, as long as it can realize information receiving and sending, and single or combined electrical signal control.

[0078] In one of the embodiments, a biochemical analysis system comprises an analysis device and the automatic cleaning solution proportioning device 100 of any of the embodiments, and the analysis device obtains dilution solution from the dilution solution tank 400 of the automatic cleaning solution proportioning device 100. It can be understood that, since the biochemical analysis system comprises the automatic cleaning solution proportioning device 100 of any of the embodiments, the biochemical analysis system also has the beneficial technical effects of the automatic cleaning solution proportioning method, which will not be repeated here.

[0079] In one of the embodiments, in combination with FIGS. 1 to 7, the automatic cleaning solution proportioning method, device and biochemical analysis system are further illustrated. The automatic cleaning solution proportioning device 100 comprises a first switching valve 500, a second switching valve 600, a liquid pump 700, a third floating ball assembly 430, a second floating ball assembly 420, a first floating ball assembly 310 and a pipe joint, etc. In this embodiment, the liquid pump 700 is a diaphragm pump.

[0080] The first switching valve 500 functions to control the switching of water and cleaning solution during the proportioning process; the second switching valve 600 functions to control the switching of the proportioning and mixing functions; the liquid pump 700 functions to provide power for the entire automatic cleaning solution proportioning device 100; the third floating ball assembly 430 functions as a signal for the termination of the proportioning; the second floating ball assembly 420 functions as a signal for the start of the proportioning; and the first floating ball assembly 310 functions as a pre-signal for the start of the proportioning. The proportioning process is further illustrated below.

[0081] First, it is determined whether the first floating ball assembly 310 is in an empty signal. If it is in an empty signal, the user is prompted to replace the concentrated cleaning solution, and the proportioning process is not performed. If the first floating ball assembly 310 is in a full signal, and after the second floating ball assembly 420 triggers an empty signal, the proportioning process is started.

[0082] The diaphragm pump is first started for a T1 time, and then the second switching valve 600 is opened. The T1 time forms a delay time for opening the second switching valve 600, which aims to wait for the stable output flow of the diaphragm pump. The diaphragm pump can be idling without water.

[0083] Then the first switching valve 500 can be directly opened or opened after a delay, and the circulating replenishment step is entered: the first switching valve 500 inputs water for a T2 time, and then the first switching valve 500 switches to input concentrated cleaning solution for a T3 time. The ratio of T3 to T2 is the target proportioning ratio, so that the proportioning ratio can be conveniently controlled by time.

[0084] The repeating cycle replenishment step is repeated until the third float ball assembly 430 triggers a full signal, at which time the last cycle replenishment step is waited to complete, and the second switch valve 600 is closed; the purpose of waiting for the last cycle replenishment step to complete is to ensure the accuracy of the last ratio, and at the same time, the diluent tank 400 has a certain amount of excess above the position of the third float ball assembly 430 triggering the full signal to ensure that there is no overflow;

[0085] After waiting for T4 time, the liquid pump 700 is closed, and the ratio is completed. The purpose of waiting for T4 time is to ensure that the cleaning solution is fully mixed; such a design uses the same diaphragm pump as the power source for water and concentrated cleaning solution, avoiding the influence of different pumps on the ratio, achieving the function of ratio with fewer components, lower cost; and the ratio can be freely set by T3 / T2; the ratio is not affected by the difference between the instruments or pumps or components, and the same pump is used to transmit the cleaning solution and water, so the ratio is stable, and the same parameters can be used to ensure that the same solution is obtained by all instruments; it also has the function of automatic mixing, which ensures that the solution after ratio is uniform.

[0086] As an example but not limitation, T1 time is about 0.5s, T2 time and T3 time can be determined according to the dilution ratio; for example, generally 1 second or 2 seconds are used; T4 time can be 30 seconds or other.

[0087] In other embodiments, two diaphragm pumps can also be used to control the injection of concentrated cleaning solution and water; air bag pumps or plunger pumps can also be used to provide power for ratio, but the cost is relatively high. The rest of the embodiments are similar and will not be repeated.

[0088] It should be noted that other embodiments of the present application also include the automatic cleaning solution ratio method, device and biochemical analysis system formed by the combination of the technical features of the above embodiments.

[0089] The technical features of the above embodiments can be combined arbitrarily, and in order to make the description concise, not all possible combinations of the technical features in the above embodiments are described, but as long as the combination of these technical features does not exist contradictory, it should be considered as the scope of the present application.

[0090] The above embodiments only express several embodiments of the present application, and the description is more specific and detailed, but it should not be understood as limiting the scope of the patent. It should be noted that for ordinary skilled in the art, without departing from the concept of the present application, a number of variations and improvements can be made, which are within the scope of the present application. Therefore, the patent protection scope of the present application should be subject to the appended claims.

Claims

1. An automatic cleaning solution mixing method, characterized by, The method comprises the steps of: According to the signal of the first floating ball assembly (310) in the concentrated cleaning liquid tank (300), the liquid pump (700) is set to a pumpable state or a non-pumpable state; When the liquid pump (700) is in the pumpable state, according to the signal of the second floating ball assembly (420) in the dilution liquid tank (400), it is determined whether to start the liquid pump (700); When the liquid pump (700) is in the starting state, the water in the water tank (200) and the concentrated cleaning liquid in the concentrated cleaning liquid tank (300) are mixed and pumped into the dilution liquid tank (400); When the liquid pump (700) is in the starting state, according to the signal of the third floating ball assembly (430) in the dilution liquid tank (400), the liquid pump (700) is closed.

2. The automatic cleaning solution mixing method according to claim 1, wherein According to the signal of the first floating ball assembly (310) in the concentrated cleaning liquid tank (300), it is determined whether the concentrated cleaning liquid needs to be supplemented, and if so, a signal is sent to require the concentrated cleaning liquid to be supplemented, and the liquid pump (700) is set to a non-pumpable state, otherwise the liquid pump (700) is set to a pumpable state; When the liquid pump (700) is in the pumpable state, according to the signal of the second floating ball assembly (420) in the dilution liquid tank (400), it is determined whether the dilution cleaning liquid needs to be supplemented, and if so, the liquid pump (700) is started.

3. The automatic cleaning solution mixing method according to claim 1, wherein According to the signal of the first floating ball assembly (310) in the concentrated cleaning liquid tank (300), the first switch valve (500) is set to an openable state and a non-openable state; wherein the openable state of the first switch valve (500) is associated with the pumpable state of the liquid pump (700), and the non-openable state of the first switch valve (500) is associated with the non-pumpable state of the liquid pump (700); When the liquid pump (700) is in the starting state, the water in the water tank (200) and the concentrated cleaning liquid in the concentrated cleaning liquid tank (300) are respectively transported to the liquid pump (700) through the first switch valve (500).

4. The automatic cleaning solution mixing method according to claim 3, wherein According to the signal of the first floating ball assembly (310) in the concentrated cleaning liquid tank (300), it is determined whether the concentrated cleaning liquid needs to be supplemented, and if so, a signal is sent to require the concentrated cleaning liquid to be supplemented, and the first switch valve (500) is set to a non-openable state, otherwise the first switch valve (500) is set to an openable state; When the first switch valve (500) is in the openable state, according to the signal of the second floating ball assembly (420) in the dilution liquid tank (400), the liquid pump (700) is pre-started and runs for a first preset time; The first switch valve (500) is started to transport the first liquid and runs for a second preset time, and then the first switch valve (500) is switched to transport the second liquid and runs for a third preset time as a cycle; wherein the first liquid is one of the water in the water tank (200) and the concentrated cleaning liquid in the concentrated cleaning liquid tank (300), and the second liquid is the other; During the cycle, according to the signal of the third floating ball assembly (430) in the dilution liquid tank (400), after completing the current cycle, the first switch valve (500) is closed; After the first switch valve (500) is closed, the liquid pump (700) is closed after a delay of a fourth preset time.

5. The automatic cleaning solution mixing method according to claim 4, wherein The automatic cleaning liquid proportioning method further comprises the step of starting the second switch valve (600) after the first switch valve (500) is closed, delaying for a fourth preset time, and then closing the liquid pump (700). The second switch valve (600) is closed after the first switch valve (500) is closed, and the liquid pump (700) is closed after a fourth preset time.

6. An automatic cleaning solution proportioning device (100), characterized in that, The automatic cleaning liquid proportioning device (100) comprises a water tank (200), a concentrated cleaning liquid tank (300), a dilution liquid tank (400), and a liquid pump (700). The water tank (200) and the concentrated cleaning liquid tank (300) are respectively connected to the liquid pump (700) through pipelines, and the liquid pump (700) is connected to the dilution liquid tank (400) through a pipeline. The automatic cleaning liquid proportioning device (100) is provided with a first floating ball assembly (310) in the concentrated cleaning liquid tank (300), which is used to set the pumpable state and the non-pumpable state of the liquid pump (700) according to the signal of the first floating ball assembly (310). The automatic cleaning liquid proportioning device (100) is provided with a second floating ball assembly (420) and a third floating ball assembly (430) in the dilution liquid tank (400), the second floating ball assembly (420) and the third floating ball assembly (430) are respectively connected to the liquid pump (700) through a line (800), and the automatic cleaning liquid proportioning device (100) is used to start the liquid pump (700) according to the signal of the second floating ball assembly (420), and is also used to close the liquid pump (700) according to the signal of the third floating ball assembly (430).

7. The automatic cleaning liquid proportioning device (100) according to claim 6, characterized in that, The automatic cleaning liquid proportioning device (100) further comprises a first switch valve (500), the water tank (200) and the concentrated cleaning liquid tank (300) are respectively connected to the first switch valve (500) through pipelines, and the first switch valve (500) is connected to the liquid pump (700) through a pipeline. The automatic cleaning liquid proportioning device (100) is used to start the first switch valve (500) and the liquid pump (700) according to the signal of the second floating ball assembly (420), and is also used to close the first switch valve (500) and the liquid pump (700) according to the signal of the third floating ball assembly (430). The first floating ball assembly (310) is used to set the first switch valve (500) to an openable state and a non-openable state. The openable state of the first switch valve (500) is associated with the pumpable state of the liquid pump (700), and the non-openable state of the first switch valve (500) is associated with the non-pumpable state of the liquid pump (700). The liquid pump (700) is used to pump the water in the water tank (200) and the concentrated cleaning liquid in the concentrated cleaning liquid tank (300) into the water tank (200) through the first switch valve (500) in the starting state. ​ 8. The automatic cleaning liquid proportioning device (100) according to claim 7, characterized in that, The automatic cleaning liquid proportioning device (100) further comprises a second switch valve (600), the first switch valve (500) and the dilution liquid tank (400) are communicated with the liquid pump (700) through the second switch valve (600) through pipelines respectively; The second float ball assembly (420) and the third float ball assembly (430) are connected with the second switch valve (600) through lines (800), and are connected with the liquid pump (700) and the first switch valve (500) through lines (800) through the second switch valve (600), the automatic cleaning liquid proportioning device (100) is used for starting the first switch valve (500), the second switch valve (600) and the liquid pump (700) according to the signal of the second float ball assembly (420), and is also used for closing the first switch valve (500), the second switch valve (600) and the liquid pump (700) according to the signal of the third float ball assembly (430).

9. The automatic cleaning liquid proportioning device (100) according to claim 8, characterized in that, The liquid pump (700) is a diaphragm pump; or, The automatic cleaning liquid proportioning device (100) is provided with a fourth float ball assembly (240) in the water tank (200), and the openable state and the unopenable state of the first switch valve (500) are jointly provided by the first float ball assembly (310) and the fourth float ball assembly (240); or, The automatic cleaning liquid proportioning device (100) further comprises an alarm (900), the alarm (900) is connected with the first float ball assembly (310) or the first switch valve (500), and the alarm (900) is used for sending a prompt signal when the liquid pump (700) is in an unopenable state; or, The first switch valve (500), the second switch valve (600) and the liquid pump (700) are linked together; or, the automatic cleaning liquid proportioning device (100) further comprises a controller, the controller is connected with the first switch valve (500), the second switch valve (600), the liquid pump (700), the first float ball assembly (310), the second float ball assembly (420) and the third float ball assembly (430) respectively, the first float ball assembly (310) is connected with the first switch valve (500) through the controller, and the second float ball assembly (420) and the third float ball assembly (430) are connected with the second switch valve (600) and the liquid pump (700) through the controller through lines (800) respectively.

10. A biochemical analysis system, characterized by, An analysis device and the automatic cleaning liquid proportioning device (100) according to any one of claims 6 to 9 are included, and the analysis device obtains dilution liquid from the dilution liquid tank (400) of the automatic cleaning liquid proportioning device (100).

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