Calcium-containing food supplement
The calcium-containing food supplement addresses bioavailability and side effects of traditional calcium supplements by using Lysine and Arginine amino acids, optimizing calcium absorption and transport, and ensuring balanced mineral intake, thereby supporting bone health and dental stability.
Patent Information
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Filing Date
- 2024-08-27
- Publication Date
- 2026-03-05
AI Technical Summary
Current calcium supplements have low bioavailability, cause gastrointestinal side effects, interfere with mineral absorption, and pose challenges for individuals with swallowing difficulties, while high doses may increase cardiovascular risks and lead to health issues like hypercalcaemia.
A calcium-containing food supplement formulated with Lysine and Arginine amino acids for improved calcium absorption and transport, along with essential vitamins and trace minerals like Vitamin D and K2, without magnesium to avoid absorption interference, and a controlled release mechanism to optimize mineral utilization.
Enhances calcium absorption and bioavailability, supports bone health and dental stability, reduces side effects, and allows for balanced mineral intake without interfering with other minerals, promoting overall bone health and fracture healing.
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Abstract
Description
[0001] DESCRIPTION
[0002] CALCIUM-CONTAINING FOOD SUPPLEMENT
[0003] TECHNICAL FIELD
[0004] The invention relates to a calcium-containing food supplement that differs from its counterparts in that it contains Lysine amino acid, which contributes to the absorption of calcium, and Arginine amino acids, which enable the utilisation of calcium in the metabolic process, which is generally developed for use in supporting bone and bone development metabolism, in order to support the prevention of Osteoporosis, Maleostasis, seen in women after menopause; in adult men, to contribute positively to the solution of problems in the absorption and utilisation of calcium that occur in bone metabolism with aging; To protect dental health and in dental implant treatment, to ensure the stability of the implant by surrounding the implant surface of the bone tissue; to ensure that children have stronger bones and, to the extent permitted by genetic factors, longer bones and therefore taller stature at the developmental age; Depending on various factors, to support the absorption and transport of calcium and utilisation thereof in the metabolic process, in skeletal problems, to support faster and better union of bone fractures.
[0005] BACKGROUND OF THE INVENTION
[0006] Calcium supplements on the market are limited by Calcium, Magnesium, Zinc, Boron, Vitamin D and Vitamin K2 (Monakinon), Vitamin C (Ascorbic acid) contents. Some food supplements available on the market contain Magnesium as well as Calcium in their formulations. Although Magnesium and Calcium are very important for bone metabolism, these two minerals should be consumed at different times because they negatively affect the absorption of each other.
[0007] Calcium-containing food supplements are common products that are often used to support bone health and to correct calcium deficiencies. These supplements are available in various forms, the most common being calcium carbonate, calcium citrate, calcium gluconate and calcium lactate. Calcium carbonate is the most preferred form due to its cost effectiveness and high calcium content. It contains about 40% elemental calcium and is easily soluble in stomach acid, thus it is recommended to be taken with meals. Calcium citrate is more suitable for individuals with low stomach acidity and can be taken on an empty stomach. This form is better absorbed than calcium carbonate and does not require stomach acid. Calcium gluconate and calcium lactate are less commonly used forms and are usually used for specific medical conditions or administered intravenously.
[0008] Current calcium supplements have some disadvantages. Firstly, some forms have low bioavailability, especially in elderly individuals or people with low gastric acid production, which may make adequate calcium intake difficult. Some forms, such as calcium carbonate, may cause gastrointestinal side effects such as constipation, bloating and flatulence, which can be uncomfortable for users. In addition, calcium supplements are often available in the form of large tablets or capsules, which may pose a challenge for individuals with swallowing difficulties. High doses of calcium supplements can interfere with the absorption of other minerals such as iron and zinc, which can make it difficult to maintain a balanced diet. Some studies suggest that taking high doses of calcium supplements may increase the risk of cardiovascular events, which is especially the case for older women. Finally, excessive calcium intake can lead to conditions such as hypercalcaemia, which can cause kidney stones, kidney dysfunction and other health problems.
[0009] In conclusion, the abovementioned problems and the inadequacy of current solutions to the issue entail an improvement in the respective technical field.
[0010] DESCRIPTION OF THE INVENTION
[0011] To eliminate the above-mentioned disadvantages and to bring new advantages to the relevant technical field , the invention relates to a calcium-containing food supplement, which is generally developed for use in supporting bone and bone development metabolism, in order to support the prevention of Osteoporosis, Maleostasis, seen in women after menopause; in adult men, to contribute positively to the solution of problems in the absorption and utilisation of calcium that occur in bone metabolism with aging; To protect dental health and in dental implant treatment; to ensure that children have stronger bones and, to the extent permitted by genetic factors, longer bones and therefore taller stature at the developmental age; Depending on various factors, to support the absorption and transport of calcium in skeletal problems, to support faster and better union of bone fractures.
[0012] The purpose of the Calcium-Containing Food Supplement of the invention is to provide normal bone health and development by supporting calcium metabolism. The invention, a bone health supplement, contains calcium, vitamin D and K2 (Monakinon), which are essential for bone health. Magnesium mineral, which is necessary for bone health, is not included in the formulation because it negatively affects the absorption of Calcium and Magnesium. Due to the problem caused by calcium in the absorption of other minerals, minerals such as Molybdenum, Zinc, Selenium are not included in the formulation, and only Manganese and Boron are included in the formulation due to trace amounts of necessity. The production of different food supplements containing these minerals is planned and it will be recommended to be used 2 hours before or after the use of Calcium Containing Supplementary Food.
[0013] The invention contains Lysine amino acid for healthy calcium absorption, Arginine amino acid for calcium transport and metabolism, Vitamin D and Vitamin K2 (Monakinon) for bone metabolism.
[0014] The use of the invention is not limited to a specific time and condition. It contributes to a healthy bone structure by continuous use. It is more important to use in dental implants, Osteoporosis, Maleostasis, Bone fractures, Implant treatment, Children's developmental age.
[0015] The invention should be used as far as possible between meals, 2 hours before or 2 hours after a meal, and snacks should be avoided. Thus, the invention should not have a negative effect on the absorption of other minerals. Since mineral absorption generally takes place in acidic environments, calcium, which is a basic agent, negatively affects the absorption of other minerals in this respect.
[0016] Although calcium is found in many foods and drinking water, lysine and Arginine amino acids have been added to solve the main problem of calcium absorption, transport and utilisation in the metabolic process. It is a product that differs from its counterparts by containing Lysine amino acid that contributes to calcium absorption and Arginine amino acids that provide the utilisation of Calcium in the metabolic process.
[0017] Vitamins and minerals, which are the basic needs of metabolism, cannot be replaced by other vitamins and minerals. In the absorption and transport of calcium, the amino acids Lysine in absorption and Arginine in transport have functions due to their molecular structure. These amino acids cannot be replaced by other amino acids. Deficiency of these amino acids causes disruptions in bone metabolism.
[0018] DETAILED DESCRIPTION OF THE INVENTION
[0019] The preferred alternatives of the embodiments of calcium-containing food supplement of invention, which are mentioned in this detailed description, are only intended for providing a better understanding of the subject-matter, and should not be construed in any restrictive sense.
[0020] The food supplement formulation according to the invention comprises, by weight, Calcium carbonate, Microcrystalline cellulose (E460 i), L-arginine, Inositol, L- lysine, Polyvinyl Pyrilidone (E1201 ),
[0021] Sodium Carboxy Methyl Cellulose (E466), L-ascorbic acid, Cholecalciferol (Vitamin D3), Magnesium Salts of Fatty Acids (E470 b), Sodium borate, Silicon Dioxide (E551 ), Menaquinone 7 (Vitamin K2), Pyridoxine hydrochloride.
[0022] Calcium-containing food supplements according to the invention contain by weight of: • 20-26% of microcrystalline cellulose (E460 i),
[0023] • 10-16% of L-arginine,
[0024] • 5-11 % of inositol,
[0025] • 5-11 % of L-lysine, • 2-8% of polyvinyl pyrilidone (E1201 ),
[0026] • 0.6-2.6% of sodium carboxy methyl cellulose (E466),
[0027] • 0.3-2.3% of L-ascorbic acid,
[0028] • 0.3-2.3% of Cholecalciferol (Vitamin D3),
[0029] • 0.2-2.2% of Magnesium Salts of Fatty Acids (E470 b), • 0.17-2.17% of Sodium borate,
[0030] • 0.3-2.3% of Silicon Dioxide (E551 ),
[0031] • 0.3-2.3% of Menaquinone 7 (vitamin K2),
[0032] • 0.01 -0.21 % of Pyridoxine hydrochloride. The substances contained in the formulation of the invention are included in the preferred embodiment of the invention as follows. 1 Tablet: 1500 mg.
[0033] The Lysine amino acid in the bone health supplement of the invention contributes to the absorption of Calcium, the Arginine amino acid contributes to the transport of Calcium to the bone tissue and bone metabolism is supported bidirectionally. Since the minerals and vitamins necessary for bone metabolism are provided, the food bone health supplement of the invention is beneficial for the formation of healthy bones and the protection of the necessary healthy bones.
[0034] Calcium Carbonate: Calcium carbonate is a common source of calcium and is often used to support bone health. It is effective in the prevention of bone resorption diseases such as osteoporosis. It also neutralises stomach acid and relieves heartburn and indigestion.
[0035] Microcrystalline Cellulose (E460 i): This ingredient is used as a filler and stabilizer. In nutritional supplements, it is used to stabilize the structure of tablets and to facilitate the dispersion of tablets.
[0036] L-Arginine: L-arginine is an amino acid and increases nitric oxide production in the body. Nitric oxide improves blood flow by dilating blood vessels and thus supports cardiovascular health. It also has the properties of strengthening the immune system and accelerating wound healing.
[0037] Inositol: Inositol is a compound related to B vitamins and plays an important role in cellular communication. It is often used to support mental health, especially to relieve symptoms of anxiety and depression. L-Lysine: L-lysine is an essential amino acid and is required for the body's protein production. It is used to prevent colds and herpes virus infections and to support the immune system. It also helps maintain muscle health.
[0038] Polyvinyl Pyrilidone (E1201 ): It is often used as a binding agent and holds the ingredients together in tablet formulations. It can also be used as a dissolving agent.
[0039] Sodium Carboxy Methyl Cellulose (E466): This ingredient is used as a stabilizer and thickener in tablets. It is also used in slow-release formulations, which helps to release the active ingredients in a controlled manner.
[0040] L-Ascorbic Acid (Vitamin C): It is a powerful antioxidant and supports the immune system. It also protects skin health and improves iron absorption.
[0041] Cholecalciferol (Vitamin D3): It supports bone health by increasing the absorption of calcium and phosphate. Vitamin D deficiency is associated with osteoporosis, osteomalacia and some immune system diseases.
[0042] Magnesium Salts of Fatty Acids (E470 b): It is often used as a lubricant or emulsifier. It makes tablets and capsules easier to swallow.
[0043] Sodium Borate: It is an ingredient with antiseptic properties. However, long-term or high-dose use of sodium borate can be harmful, so it should be used with caution.
[0044] Silicone Dioxide (E551 ): It is used as an anti-coagulant and prevents the tablets from sticking together.
[0045] Menaquinone 7 (Vitamin K2): Vitamin K2 supports bone and cardiovascular health. It helps calcium to accumulate in the bones and prevents it from accumulating in the arteries. Pyridoxine Hydrochloride (Vitamin B6): Vitamin B6 plays an important role in protein, fat and carbohydrate metabolism. It supports the health of the nervous system and strengthens the immune system.
[0046] Calcium Karbonate:
[0047] • Function: Calcium carbonate increases calcium levels in the body. Calcium plays a critical role in many biological processes such as maintaining the structure of bones and teeth, muscle function, nerve conduction and blood clotting.
[0048] • Effect: It increases bone density and reduces the risk of osteoporosis. It relieves heartburn by neutralising stomach acid.
[0049] Microcrystalline Sellulose (E460 i)
[0050] • Function: It functions as an indigestible fibre and can regulate bowel movements. It is also used as a binder and stabilizer in tablet formulations.
[0051] • Effect: It contributes to the healthy functioning of the digestive system and keeps the tablets in proper form.
[0052] L-Arginine:
[0053] • Function: L-arginine promotes dilation of blood vessels by increasing nitric oxide production. This in turn improves blood flow.
[0054] • Effects: It may help lower blood pressure, promote muscle growth and strengthen the immune system.
[0055] Inositol:
[0056] • Function: It is involved in the structure of cell membranes and intracellular signalling. It is especially effective in nervous system health and mood regulation.
[0057] • Effects: It may relieve symptoms of anxiety and depression, support liver function. L-Lysine:
[0058] • Function: It is an essential amino acid and plays an important role in protein synthesis. It also improves calcium absorption.
[0059] • Effect: It supports the immune system, can help prevent colds and herpes virus, supports muscle and bone health.
[0060] Polyvinyl Pyrilidone (E1201 ):
[0061] • Function: It is used as a binder and disintegration accelerator in tablets. It also functions as a dissolving agent.
[0062] • Effect: It ensures that the tablets are properly dispersed, so that the absorption of the active ingredients is optimised.
[0063] Sodium Karboxy Methyl Cellulose (E466):
[0064] • Function: It has thickening and emulsion stabilizing properties. It is also used in slow-release formulations.
[0065] • Effect: It provides a controlled release of the active ingredients, contributing to a long-lasting effect.
[0066] L-Ascorbic Acid (Vitamin C):
[0067] • Function: It provides protection against free radicals as a powerful antioxidant. It promotes collagen production and supports the immune system.
[0068] • Effect: It improves skin health, accelerates wound healing, increases iron absorption and supports immune function.
[0069] Cholecalciferol (Vitamin D3):
[0070] • Function: It regulates calcium and phosphate metabolism and supports bone health.
[0071] • Effects: It increases bone mineralisation, reduces the risk of osteoporosis and strengthens the immune system.
[0072] Magnesium Salts of Fatty Acids (E470 b):
[0073] • Function: It is used as a lubricant and emulsifier. Effect: It facilitates the passage of the tablets through the digestive tract and increases their absorption.
[0074] Sodium Borate:
[0075] • Function: It has antiseptic properties and is used as a stabilizer.
[0076] • Effect: It may support digestive health with its antibacterial properties; however, caution should be exercised in long-term use.
[0077] Silicon Dioxide (E551 ):
[0078] • Function: It functions as an anti-coagulant and prevents moisture retention.
[0079] • Effect: It increases the physical stability of the tablets and prevents them from sticking together.
[0080] Menaquinone 7 (vitamin K2):
[0081] • Function: Vitamin K2 enables calcium to be stored in bones and prevents its deposition in soft tissues.
[0082] • Effect: It supports bone health and may reduce the risk of cardiovascular disease.
[0083] Pyridoxine Hydrochloride (Vitamin B6):
[0084] • Function: It is involved in protein, carbohydrate and lipid metabolism. It also helps the nervous system to function properly.
[0085] • Effect: It supports energy production, protects neurological functions and strengthens the immune system.
[0086] Below are the areas where this specific formulation creates a new and unexpected technical effect:
[0087] Synergistic Effect:
[0088] The components in the above mentioned composition work together to create a synergistic effect. For example, the nitric oxide production-enhancing effect of L- arginine and the beneficial effects of L-lysine and inositol on the nervous system are combined to simultaneously optimise cardiovascular and nervous system health. Technical Effect: This synergistic effect provides an overall health benefit that is greater than the benefits that individual ingredients alone can provide.
[0089] The ingredients in this composition enhance the absorption and bioavailability of the others. For example, L-ascorbic acid (Vitamin C) improves the absorption of iron and calcium, while Vitamins K2 and D3 help the correct deposition of calcium in the bones.
[0090] Technical Effect: This combination optimises the absorption of minerals and vitamins, allowing them to be used more effectively in the body. This is particularly important in supporting bone health and the immune system.
[0091] Controlled Release and Effective Distribution:
[0092] Ingredients such as Sodium Carboxy Methyl Cellulose (E466) and Polyvinyl Pyrylidone (E1201 ) ensure controlled release of the ingredients. This ensures a stable presence of the active ingredients in the body over a long period of time.
[0093] Technical Effect: Such a controlled release requires users to take fewer doses per day, which is advantageous in terms of ease of use and patient compliance.
[0094] Multi-System Supporting Effect:
[0095] Description: The above composition supports multiple biological systems (e.g., bone health, cardiovascular system, nervous system) simultaneously. This is particularly important in the management of complex health conditions.
[0096] Technical Effect: This versatile supplement allows users to achieve multiple health goals with a single supplement, which reduces the use of multiple products and simplifies treatment processes.
[0097] These technical effects indicate that the composition goes beyond the known state of the art and offers an innovative approach. Such a formulation is considered to fulfil the criteria of novelty, inventive step and industrial applicability in terms of patentability. The calcium-containing food supplement of the invention is in tablet form and has a size suitable for swallowing.
Claims
CLAIMS1 . A calcium-containing food supplement, characterized in that it contains: in the whole composition by weight of- 30-36% of calcium carbonate,- 20-26% of microcrystalline cellulose (E460 i),- 10-16% of L-arginine,- 5-11 % of inositol,- 5-11 % of L-lysine,- 2-8% of polyvinyl pyrilidone (E1201 ),- 0.6-2.6% of sodium carboxy methyl cellulose (E466),- 0.3-2.3% of L-ascorbic acid,- 0.3-2.3% of Cholecalciferol (Vitamin D3),- 0.2-2.2% of Magnesium Salts of Fatty Acids (E470 b),- 0.17-2.17% of Sodium borate,- 0.3-2.3% of Silicon Dioxide (E551 ),- 0.3-2.3% of Menaquinone 7 (vitamin K2),- 0.01 -0.21 % of Pyridoxine hydrochloride.
Citation Information
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