Bionic polyetheretherketone dental implant material and method for preparing same

Abstract

The present invention relates to the field of biomedical material technology, and in particular, to a bionic polyetheretherketone dental implant material and a method for preparing same. The method comprises: mixing polyetheretherketone with a modified material and a glass fiber in ethanol, and drying the mixture to give a series of composite powders with gradients in the contents of the modified material and the glass fiber; compressing composite powders containing different amounts of the glass fiber / modified material / polyetheretherketone into composite powder disks, and then stacking the composite powder disks in a descending order of glass fiber material content and an ascending order of modified material content, and forming to give a composite material preform; and performing CAD / CAM cutting on the composite material preform according to a designed implant model to give the bionic polyetheretherketone dental implant. The present invention provides a precise bionic polyetheretherketone dental implant material with a mechanical and aesthetic gradient from neck to root and osteogenic and anti-microbial properties.

Description

A biomimetic polyether ether ketone dental implant material and a preparation method thereof TECHNICAL FIELD

[0001] The present application relates to the technical field of biomedical materials, and particularly relates to a biomimetic polyether ether ketone dental implant material and a preparation method thereof. BACKGROUND

[0002] At present, pure titanium and titanium alloy are the most commonly used implant materials, which have the advantages of wear resistance, corrosion resistance, good cell and tissue compatibility, and are widely used in orthopedic implantation and other aspects. However, the elastic modulus (110 GPa) of titanium and titanium alloy is significantly higher than the elastic modulus (0.02-20 GPa) of human bone, which is not matched with the elastic modulus of natural alveolar bone, resulting in stress shielding, easy to cause occlusal stress to concentrate in the local area, and mechanical complications such as rapid absorption of surrounding jaw bone or implant fracture, leading to implant failure.

[0003] Polyether ether ketone (PEEK) is a high-performance engineering plastic, which is widely used in the medical field, especially in orthopedic and dental implants, due to its excellent mechanical properties, heat resistance and biocompatibility. Polyether ether ketone has similar elastic modulus to human bone, good mechanical properties, wear resistance and biocompatibility, and is an FDA-certified biocompatible material, which is an ideal bone substitute. However, polyether ether ketone is a hydrophobic material with biological and chemical inertness, which has disadvantages in bone bonding, limiting its further application. Although the elastic modulus of PEEK implant material is similar to that of human bone, there are deficiencies in mechanical strength, biocompatibility and antibacterial performance, which are difficult to meet the various needs in the complex oral environment. In addition, the natural alveolar bone gradually transitions from the cortex to the cancellous bone from the crown to the root, and the elastic modulus gradually decreases. The implant has different functions in the vertical direction, the neck is the main part to bear the force, which needs to match the elastic modulus of the surrounding alveolar bone to prevent stress shielding; the bottom needs to form good bone bonding with the surrounding alveolar bone to stabilize the implant. The current dental implant is a uniform modulus implant, which fails to precisely imitate the structure, function and aesthetic gradient from the neck to the root.

[0004] Therefore, it is an urgent problem to provide a biomimetic dental implant with antibacterial, neck-to-root mechanical (elastic modulus) and aesthetic gradual changes, which has osteogenic and antibacterial properties. SUMMARY

[0005] The present application aims to provide a biomimetic polyether ether ketone dental implant material and a preparation method thereof, to solve the problem that the current dental implant fails to precisely imitate the structure, function and aesthetic gradient from the neck to the root.

[0006] In order to achieve the above-mentioned application purposes, the present application provides the following technical solutions:

[0007] The application provides a preparation method of a biomimetic polyether ether ketone dental implant material, comprising the following steps:

[0008] The first polyether ether ketone, the first glass fiber are mixed in the first ethanol to carry out the first mixing, and the first drying is carried out after the first mixing is finished, and the first composite powder is obtained;The content of the first glass fiber in the first composite powder is 15wt%;

[0009] The second polyether ether ketone, the second glass fiber and the second modified material are mixed in the second ethanol to carry out the second mixing, and the second drying is carried out after the second mixing is finished, and the second composite powder is obtained;The content of the second glass fiber in the second composite powder is 12wt%;The content of the second modified material in the second composite powder is 0.4wt%;

[0010] The third polyether ether ketone, the third glass fiber and the third modified material are mixed in the third ethanol to carry out the third mixing, and the third drying is carried out after the third mixing is finished, and the third composite powder is obtained;The content of the third glass fiber in the third composite powder is 9wt%;The content of the third modified material in the third composite powder is 0.8wt%;

[0011] The fourth polyether ether ketone, the fourth glass fiber and the fourth modified material are mixed in the fourth ethanol to carry out the fourth mixing, and the fourth drying is carried out after the fourth mixing is finished, and the fourth composite powder is obtained;The content of the fourth glass fiber in the fourth composite powder is 6wt%;The content of the fourth modified material in the fourth composite powder is 1.2wt%;

[0012] The fifth polyether ether ketone, the fifth glass fiber and the fifth modified material are mixed in the fifth ethanol to carry out the fifth mixing, and the fifth drying is carried out after the fifth mixing is finished, and the fifth composite powder is obtained;The content of the fifth glass fiber in the fifth composite powder is 3wt%;The content of the fifth modified material in the fifth composite powder is 1.6wt%;

[0013] The sixth polyether ether ketone, the sixth modified material are mixed in the sixth ethanol to carry out the sixth mixing, and the sixth drying is carried out after the sixth mixing is finished, and the sixth composite powder is obtained;The content of the sixth modified material in the sixth composite powder is 2wt%;

[0014] The first composite powder, the second composite powder, the third composite powder, the fourth composite powder, the fifth composite powder and the sixth composite powder are pressed respectively, and the first composite powder disc, the second composite powder disc, the third composite powder disc, the fourth composite powder disc, the fifth composite powder disc and the sixth composite powder disc are obtained;

[0015] The first composite powder disc, the second composite powder disc, the third composite powder disc, the fourth composite powder disc, the fifth composite powder disc and the sixth composite powder disc are stacked from top to bottom in turn, and vacuum hot pressing is carried out, and the polyether ether ketone composite material blank is obtained;

[0016] Designing a dental implant digital model, then function modeling to get the implant model, according to the designed implant model, using CAD / CAM cutting, to get the bionic polyether ether ketone dental implant material;

[0017] The second modified material, the third modified material, the fourth modified material, the fifth modified material, and the sixth modified material are independently Michaelene, silicene, two-dimensional MOF, black scale, metal oxide, or transition metal sulfide.

[0018] Preferably, in the preparation method of the bionic polyether ether ketone dental implant material, the D of the first polyether ether ketone, the second polyether ether ketone, the third polyether ether ketone, the fourth polyether ether ketone, the fifth polyether ether ketone, and the sixth polyether ether ketone is independently 0.9-1.1. 50 Independently 30-80 μm.

[0019] Preferably, in the preparation method of the bionic polyether ether ketone dental implant material, the diameter of the first glass fiber, the second glass fiber, the third glass fiber, the fourth glass fiber, and the fifth glass fiber is independently 5-20 μm; and the length of the first glass fiber, the second glass fiber, the third glass fiber, the fourth glass fiber, and the fifth glass fiber is independently 50-200 μm.

[0020] Preferably, in the preparation method of the bionic polyether ether ketone dental implant material, the temperature of the first mixing, the second mixing, the third mixing, the fourth mixing, the fifth mixing, and the sixth mixing is independently 20-30℃, and the time of the first mixing, the second mixing, the third mixing, the fourth mixing, the fifth mixing, and the sixth mixing is independently 1-3 h.

[0021] Preferably, in the preparation method of the bionic polyether ether ketone dental implant material, the thickness of the first composite powder disc, the second composite powder disc, the third composite powder disc, the fourth composite powder disc, the fifth composite powder disc, and the sixth composite powder disc is independently 2-4 mm.

[0022] Preferably, in the preparation method of the bionic polyether ether ketone dental implant material, the temperature of the vacuum hot pressing is 350-380℃, and the time of the vacuum hot pressing is 0.5-1 h.

[0023] The application also provides a bionic polyether ether ketone dental implant material prepared by the preparation method of the bionic polyether ether ketone dental implant material.

[0024] According to the above technical solution, compared with the prior art, the application has the following beneficial effects:

[0025] (1) Establish a mechanical bionic polyether ether ketone dental implant with a gradient change from the neck to the root of the elastic modulus from high to low. Use glass fiber for mechanical reinforcement, use modified materials for biological modification, and gradually weaken the mechanics and gradually enhance the biological activity from the neck to the root.

[0026] (2) Establish an aesthetic bionic polyether ether ketone dental implant with a gradient change from the neck to the root of the color from light to dark.

[0027] (3) Polyether ether ketone is a hydrophobic material, and the added modified material is a hydrophilic material, so the hydrophilicity of the modified polyether ether ketone composite material is enhanced, and the hydrophilicity gradually increases with the increase of the content. Theoretically, the increase of hydrophilicity will increase the osteogenesis effect, and then a functional bionic polyether ether ketone dental implant with gradually enhanced hydrophilicity and osteogenesis from the neck to the root is established.

[0028] (4) Establish an antibacterial polyether ether ketone dental implant with photothermal sterilization performance. The added biological modification material has strong absorption to near-infrared, and can convert light energy into heat energy. The antibacterial effect of E. coli and S. aureus is enhanced with the increase of the content of the biological additive under the irradiation of 808nm near-infrared laser for 5min.

[0029] (5) The modified material added in the present application will gradually degrade after the implant is implanted, forming a porous polyether ether ketone, which is beneficial to the further growth of cells and improves the bone bonding efficiency. BRIEF DESCRIPTION OF DRAWINGS

[0030] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, the following will briefly introduce the drawings needed to be used in the embodiment or prior art description.

[0031] Fig. 1 is a schematic diagram of the bionic polyether ether ketone dental implant material prepared in Example 1;

[0032] Fig. 2 is the hydrophilic performance of the first composite powder disc, the second composite powder disc, the third composite powder disc, the fourth composite powder disc, the fifth composite powder disc and the sixth composite powder disc in Example 1;

[0033] Fig. 3 is the antibacterial performance of the first composite powder disc, the second composite powder disc, the third composite powder disc, the fourth composite powder disc, the fifth composite powder disc and the sixth composite powder disc in Example 1. DETAILED DESCRIPTION

[0034] The present application provides a preparation method of a bionic polyether ether ketone dental implant material, comprising the following steps:

[0035] mixing the first polyether ether ketone, the first glass fiber in the first ethanol, after the first mixing is completed, the first drying is carried out, and the first composite powder is obtained;The content of the first glass fiber in the first composite powder is 15wt%;

[0036] mixing the second polyether ether ketone, the second glass fiber and the second modified material in the second ethanol, after the second mixing is completed, the second drying is carried out, and the second composite powder is obtained;The content of the second glass fiber in the second composite powder is 12wt%;The content of the second modified material in the second composite powder is 0.4wt%;

[0037] mixing the third polyether ether ketone, the third glass fiber and the third modified material in the third ethanol, after the third mixing is completed, the third drying is carried out, and the third composite powder is obtained;The content of the third glass fiber in the third composite powder is 9wt%;The content of the third modified material in the third composite powder is 0.8wt%;

[0038] mixing the fourth polyether ether ketone, the fourth glass fiber and the fourth modified material in the fourth ethanol, after the fourth mixing is completed, the fourth drying is carried out, and the fourth composite powder is obtained;The content of the fourth glass fiber in the fourth composite powder is 6wt%;The content of the fourth modified material in the fourth composite powder is 1.2wt%;

[0039] mixing the fifth polyether ether ketone, the fifth glass fiber and the fifth modified material in the fifth ethanol, after the fifth mixing is completed, the fifth drying is carried out, and the fifth composite powder is obtained;The content of the fifth glass fiber in the fifth composite powder is 3wt%;The content of the fifth modified material in the fifth composite powder is 1.6wt%;

[0040] mixing the sixth polyether ether ketone, the sixth modified material in the sixth ethanol, after the sixth mixing is completed, the sixth drying is carried out, and the sixth composite powder is obtained;The content of the sixth modified material in the sixth composite powder is 2wt%;

[0041] The first composite powder, the second composite powder, the third composite powder, the fourth composite powder, the fifth composite powder and the sixth composite powder are pressed respectively, and the first composite powder disc, the second composite powder disc, the third composite powder disc, the fourth composite powder disc, the fifth composite powder disc and the sixth composite powder disc are obtained;

[0042] The first composite powder disc, the second composite powder disc, the third composite powder disc, the fourth composite powder disc, the fifth composite powder disc and the sixth composite powder disc are stacked from top to bottom, and vacuum hot pressing is carried out, and the polyether ether ketone composite material blank is obtained;

[0043] The digital model of the dental implant is designed, and then a function modeling is performed to obtain an implant model, and a polyether ether ketone composite blank is cut according to the designed implant model by using CAD / CAM to obtain a bionic polyether ether ketone dental implant material.

[0044] In the application, the second modified material, the third modified material, the fourth modified material, the fifth modified material, and the sixth modified material are independently preferably micene, silicene, two-dimensional MOF, black phosphorus, metal oxide or transition metal sulfide, further preferably micene, silicene, two-dimensional MOF or black phosphorus, and more preferably micene or black phosphorus; the modified material has antibacterial and osteogenic properties.

[0045] In the application, the D 50 The diameter is independently preferably 30-80 mu m, further preferably 40-60 mu m, and more preferably 50-55 mu m.

[0046] In the application, the diameter of the first glass fiber, the second glass fiber, the third glass fiber, the fourth glass fiber, and the fifth glass fiber is independently preferably 5-20 mu m, further preferably 8-15 mu m, and more preferably 12-13 mu m; and the length of the first glass fiber, the second glass fiber, the third glass fiber, the fourth glass fiber, and the fifth glass fiber is independently preferably 50-200 mu m, further preferably 80-160 mu m, and more preferably 100-150 mu m.

[0047] In the application, the ratio of the first ethanol to the first polyether ether ketone is preferably 2-4 mL:1 g, further preferably 2.5-3.5 mL:1 g, and more preferably 2.8-3 mL:1 g.

[0048] In the application, the ratio of the second ethanol to the second polyether ether ketone is preferably 2-4 mL:1 g, further preferably 2.5-3.5 mL:1 g, and more preferably 2.8-3 mL:1 g.

[0049] In the application, the ratio of the third ethanol to the third polyether ether ketone is preferably 2-4 mL:1 g, further preferably 2.5-3.5 mL:1 g, and more preferably 2.8-3 mL:1 g.

[0050] In the application, the ratio of the fourth ethanol to the fourth polyether ether ketone is preferably 2-4 mL:1 g, further preferably 2.5-3.5 mL:1 g, and more preferably 2.8-3 mL:1 g.

[0051] In the present application, the use amount ratio of the fifth ethanol and the fifth polyether ether ketone is preferably 2-4 mL:1 g, further preferably 2.5-3.5 mL:1 g, and more preferably 2.8-3 mL:1 g.

[0052] In the present application, the use amount ratio of the sixth ethanol and the sixth polyether ether ketone is preferably 2-4 mL:1 g, further preferably 2.5-3.5 mL:1 g, and more preferably 2.8-3 mL:1 g.

[0053] In the present application, the temperature of the first mixing, the second mixing, the third mixing, the fourth mixing, the fifth mixing and the sixth mixing is preferably 20-30℃, further preferably 22-28℃, and more preferably 24-25℃; and the mixing time is preferably 1-3 h, further preferably 1.5-2.5 h, and more preferably 2 h.

[0054] In the present application, the first mixing, the second mixing, the third mixing, the fourth mixing, the fifth mixing and the sixth mixing are independently further comprised of filtering.

[0055] In the present application, the temperature of the first drying, the second drying, the third drying, the fourth drying, the fifth drying and the sixth drying is independently preferably 60-80℃, further preferably 65-75℃, and more preferably 68-70℃; and the drying time is independently preferably 3-5 h, further preferably 3.5-4.5 h, and more preferably 4 h.

[0056] In the present application, the thickness of the first composite powder disc, the second composite powder disc, the third composite powder disc, the fourth composite powder disc, the fifth composite powder disc and the sixth composite powder disc is independently preferably 2-4 mm, further preferably 2.5-3.5 mm, and more preferably 3 mm.

[0057] In the present application, the temperature of the vacuum hot pressing is preferably 350-380℃, further preferably 360-370℃, and more preferably 350℃; and the vacuum hot pressing time is preferably 0.5-1 h, further preferably 0.5-0.75 h, and more preferably 0.5 h.

[0058] The present application also provides a bionic polyether ether ketone dental implant prepared by the preparation method of the bionic polyether ether ketone dental implant.

[0059] The technical solutions in the embodiments of the present application will be described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative work fall within the protection scope of the present application.

[0060] In Example 1 below, the D of the polyetheretherketone powder 50 The diameter of the glass fiber is 50 μm; the diameter of the glass fiber is 5 μm, and the length of the glass fiber is 80 μm; [The text abruptly ends here, likely due to an incomplete sentence or missing information.] X The thin film was purchased from Xianfeng Nano, CAS: 12363-89-2.

[0061] In Example 2 below, the D of the polyetheretherketone powder 50 The diameter of the glass fiber is 60μm; the diameter of the glass fiber is 12μm and the length of the glass fiber is 120μm; the black scales were purchased from Xianfeng Nano, CAS: 7723-14-0.

[0062] Example 1

[0063] 100g of polyetheretherketone powder and glass fiber were mixed in 200mL of ethanol, magnetically stirred at 25°C for 2h, filtered, and dried at 70°C for 4h to obtain the first composite powder; the glass fiber content in the first composite powder was 15wt%.

[0064] 100g of polyetheretherketone powder, glass fiber, and methyl methacrylate (Ti3C2T) were added. X The thin films were mixed in 200 mL of ethanol, magnetically stirred at 25 °C for 2 h, filtered, and dried at 70 °C for 4 h to obtain the second composite powder; the glass fiber content in the second composite powder was 12 wt%; the macene (Ti3C2T) in the second composite powder was... X The content of the thin slices is 0.4 wt%.

[0065] 100g of polyetheretherketone powder, glass fiber, and methyl methacrylate (Ti3C2T) were added. X The thin films were mixed in 200 mL of ethanol, magnetically stirred at 25 °C for 2 h, filtered, and dried at 70 °C for 4 h to obtain the third composite powder; the glass fiber content in the third composite powder was 9 wt%; the macene (Ti3C2T) in the third composite powder was... X The content of the thin slices is 0.8 wt%.

[0066] 100g of polyetheretherketone powder, glass fiber, and methyl methacrylate (Ti3C2T) were added. X The thin films were mixed in 200 mL of ethanol, magnetically stirred at 25 °C for 2 h, filtered, and dried at 70 °C for 4 h to obtain the fourth composite powder; the glass fiber content in the fourth composite powder was 6 wt%; the content of micene (Ti3C2T) in the fourth composite powder was... X The content of thin slices is 1.2 wt%.

[0067] 100g of polyetheretherketone powder, glass fiber, and methyl methacrylate (Ti3C2T) were added. X) The flakes were mixed in 200 mL of ethanol, and after magnetic stirring at 25 °C for 2 h, filtration and drying at 70 °C for 4 h were performed to obtain a fifth composite powder; the content of glass fibers in the fifth composite powder was 3 wt%; the content of MXene (Ti3C2T X ) The content of flakes was 1.6 wt%;

[0068] 100 g of polyether ether ketone powder, MXene (Ti3C2T X ) The flakes were mixed in 200 mL of ethanol, and after magnetic stirring at 25 °C for 2 h, filtration and drying at 70 °C for 4 h were performed to obtain a sixth composite powder; the content of MXene (Ti3C2T X ) The content of flakes was 2 wt%;

[0069] The first composite powder disc, the second composite powder disc, the third composite powder disc, the fourth composite powder disc, the fifth composite powder disc, and the sixth composite powder disc were pressed to obtain a first composite powder disc with a thickness of 3 mm, a second composite powder disc with a thickness of 3 mm, a third composite powder disc with a thickness of 3 mm, a fourth composite powder disc with a thickness of 3 mm, a fifth composite powder disc with a thickness of 3 mm, and a sixth composite powder disc with a thickness of 3 mm.

[0070] The first composite powder disc, the second composite powder disc, the third composite powder disc, the fourth composite powder disc, the fifth composite powder disc, and the sixth composite powder disc were stacked in order, with the sixth composite powder disc at the bottom and the first composite powder disc at the top, and then vacuum hot pressing was performed at 350 °C for 30 min to obtain a polyether ether ketone composite blank.

[0071] A dental implant digital model was designed, and then a function modeling was performed to obtain an implant model. The polyether ether ketone composite blank was cut according to the designed implant model using CAD / CAM to obtain a biomimetic polyether ether ketone dental implant material.

[0072] A schematic diagram of the biomimetic polyether ether ketone dental implant material prepared in Example 1 is shown in FIG. 1. As shown in FIG. 1, the aesthetic biomimetic polyether ether ketone dental implant material has a gradient change in color from light to dark from the neck to the root.

[0073] The hydrophilic properties of the first composite powder disc, the second composite powder disc, the third composite powder disc, the fourth composite powder disc, the fifth composite powder disc, and the sixth composite powder disc in Example 1 are shown in FIG. 2. As shown in FIG. 2, polyether ether ketone is a hydrophobic material, MXene is a hydrophilic material, the hydrophilicity of the modified polyether ether ketone composite material is enhanced, and the hydrophilicity gradually increases with the increase of the content of MXene. Theoretically, the increase of hydrophilicity will also increase the effect of promoting osteogenesis.

[0074] The antibacterial properties of the first composite powder disc, the second composite powder disc, the third composite powder disc, the fourth composite powder disc, the fifth composite powder disc, and the sixth composite powder disc in Example 1 are shown in FIG. 3. As can be seen from FIG. 3, the antibacterial effect on E. coli and S. aureus is enhanced with the increase of the content of the biological additive when the implant material is irradiated by 808 nm near-infrared laser for 5 min.

[0075] Example 2

[0076] 100 g of polyether ether ketone powder and glass fibers were mixed in 250 mL of ethanol, and after magnetic stirring at 25 °C for 2 h, filtration and drying at 70 °C for 4 h were performed to obtain a first composite powder; the content of glass fibers in the first composite powder was 15 wt%;

[0077] 100 g of polyether ether ketone powder, glass fibers, and black scales were mixed in 250 mL of ethanol, and after magnetic stirring at 25 °C for 2 h, filtration and drying at 70 °C for 4 h were performed to obtain a second composite powder; the content of glass fibers in the second composite powder was 12 wt%; the content of black scales in the second composite powder was 0.4 wt%;

[0078] 100 g of polyether ether ketone powder, glass fibers, and black scales were mixed in 250 mL of ethanol, and after magnetic stirring at 25 °C for 2 h, filtration and drying at 70 °C for 4 h were performed to obtain a third composite powder; the content of glass fibers in the third composite powder was 9 wt%; the content of black scales in the third composite powder was 0.8 wt%;

[0079] 100 g of polyether ether ketone powder, glass fibers, and black scales were mixed in 250 mL of ethanol, and after magnetic stirring at 25 °C for 2 h, filtration and drying at 70 °C for 4 h were performed to obtain a fourth composite powder; the content of glass fibers in the fourth composite powder was 6 wt%; the content of black scales in the fourth composite powder was 1.2 wt%;

[0080] 100 g of polyether ether ketone powder, glass fibers, and black scales were mixed in 250 mL of ethanol, and after magnetic stirring at 25 °C for 2 h, filtration and drying at 70 °C for 4 h were performed to obtain a fifth composite powder; the content of glass fibers in the fifth composite powder was 3 wt%; the content of black scales in the fifth composite powder was 1.6 wt%;

[0081] 100 g of polyether ether ketone powder and black scales were mixed in 250 mL of ethanol, and after magnetic stirring at 25 °C for 2 h, filtration and drying at 70 °C for 4 h were performed to obtain a sixth composite powder; the content of black scales in the sixth composite powder was 2 wt%;

[0082] The first composite powder, the second composite powder, the third composite powder, the fourth composite powder, the fifth composite powder and the sixth composite powder are pressed respectively to obtain a first composite powder disc with a thickness of 3mm, a second composite powder disc with a thickness of 3mm, a third composite powder disc with a thickness of 3mm, a fourth composite powder disc with a thickness of 3mm, a fifth composite powder disc with a thickness of 3mm and a sixth composite powder disc with a thickness of 3mm;

[0083] The first composite powder disc, the second composite powder disc, the third composite powder disc, the fourth composite powder disc, the fifth composite powder disc and the sixth composite powder disc are stacked in sequence, with the sixth composite powder disc being the bottom layer and the first composite powder disc being the top layer, and then vacuum hot pressing is performed at 360 DEG C for 40min to obtain a polyether ether ketone composite blank;

[0084] A dental implant digital model is designed, and then function modeling is performed to obtain an implant model; and the polyether ether ketone composite blank is cut using CAD / CAM according to the designed implant model to obtain a biomimetic polyether ether ketone dental implant material.

[0085] The above only describes the preferred embodiments of the present application, and it should be noted that those skilled in the art can make several improvements and refinements without departing from the principles of the present application, and these improvements and refinements should also be considered as the protection scope of the present application.

Claims

1. A method for preparing a biomimetic polyether ether ketone dental implant material, characterized by, The method comprises the following steps: The first polyether ether ketone, the first glass fiber are mixed in the first ethanol to carry out the first mixing, the first drying is carried out after the first mixing is finished, and the first composite powder is obtained;The content of the first glass fiber in the first composite powder is 15wt%; The second polyether ether ketone, the second glass fiber and the second modified material are mixed in the second ethanol to carry out the second mixing, the second drying is carried out after the second mixing is finished, and the second composite powder is obtained;The content of the second glass fiber in the second composite powder is 12wt%;The content of the second modified material in the second composite powder is 0.4wt%; The third polyether ether ketone, the third glass fiber and the third modified material are mixed in the third ethanol to carry out the third mixing, the third drying is carried out after the third mixing is finished, and the third composite powder is obtained;The content of the third glass fiber in the third composite powder is 9wt%;The content of the third modified material in the third composite powder is 0.8wt%; The fourth polyether ether ketone, the fourth glass fiber and the fourth modified material are mixed in the fourth ethanol to carry out the fourth mixing, the fourth drying is carried out after the fourth mixing is finished, and the fourth composite powder is obtained;The content of the fourth glass fiber in the fourth composite powder is 6wt%;The content of the fourth modified material in the fourth composite powder is 1.2wt%; The fifth polyether ether ketone, the fifth glass fiber and the fifth modified material are mixed in the fifth ethanol to carry out the fifth mixing, the fifth drying is carried out after the fifth mixing is finished, and the fifth composite powder is obtained;The content of the fifth glass fiber in the fifth composite powder is 3wt%;The content of the fifth modified material in the fifth composite powder is 1.6wt%; The sixth polyether ether ketone, the sixth modified material are mixed in the sixth ethanol to carry out the sixth mixing, the sixth drying is carried out after the sixth mixing is finished, and the sixth composite powder is obtained;The content of the sixth modified material in the sixth composite powder is 2wt%; The first composite powder, the second composite powder, the third composite powder, the fourth composite powder, the fifth composite powder and the sixth composite powder are pressed respectively, and the first composite powder disc, the second composite powder disc, the third composite powder disc, the fourth composite powder disc, the fifth composite powder disc and the sixth composite powder disc are obtained; The first composite powder disc, the second composite powder disc, the third composite powder disc, the fourth composite powder disc, the fifth composite powder disc and the sixth composite powder disc are stacked from top to bottom in turn, and vacuum hot pressing is carried out, and the polyether ether ketone composite material blank is obtained; The digital model of the dental implant is designed, then the function modeling is carried out to obtain the implant model, and the polyether ether ketone composite material blank is cut using CAD / CAM according to the designed implant model, and the bionic polyether ether ketone dental implant material is obtained. The second modified material, the third modified material, the fourth modified material, the fifth modified material and the sixth modified material are independently micene, silicene, two-dimensional MOF, black scale, metal oxide or transition metal sulfide.

2. The method for preparing the biomimetic polyetheretherketone dental implant material according to claim 1, characterized in that, D of the first polyether ether ketone, the second polyether ether ketone, the third polyether ether ketone, the fourth polyether ether ketone, the fifth polyether ether ketone, and the sixth polyether ether ketone is 0.1 to 0.3 50 independently 30 to 80 μm.

3. The method for preparing the biomimetic polyetheretherketone dental implant material according to claim 2, characterized in that, The diameter of the first glass fiber, the second glass fiber, the third glass fiber, the fourth glass fiber and the fifth glass fiber is independently 5-20μm;The length of the first glass fiber, the second glass fiber, the third glass fiber, the fourth glass fiber and the fifth glass fiber is independently 50-200μm.

4. The method for preparing the biomimetic polyetheretherketone dental implant material according to claim 3, characterized in that, The temperature of the first mixing, the second mixing, the third mixing, the fourth mixing, the fifth mixing and the sixth mixing is independently 20-30℃, and the time of the first mixing, the second mixing, the third mixing, the fourth mixing, the fifth mixing and the sixth mixing is independently 1-3h.

5. The method of claim 3 or 4, wherein the method is characterized by, The thickness of the first composite powder disc, the second composite powder disc, the third composite powder disc, the fourth composite powder disc, the fifth composite powder disc and the sixth composite powder disc is independently 2-4mm.

6. The method for preparing the biomimetic polyetheretherketone dental implant material according to claim 5, characterized in that, The temperature of the vacuum hot pressing is 350-380℃, and the time of the vacuum hot pressing is 0.5-1h.

7. The bionic polyether ether ketone dental implant material prepared by the preparation method of the bionic polyether ether ketone dental implant material according to any one of claims 1-6.

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