Electrochemical sensor and use thereof

The electrochemical sensor addresses the limitations of traditional assays by using a sample activating composition to detect and quantify ferritin rapidly and reliably, improving point-of-care diagnostics with reduced sample volumes and enhanced robustness.

WO2026107555A1PCT designated stage Publication Date: 2026-05-28DEAKIN UNIVERSITY
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Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
DEAKIN UNIVERSITY
Filing Date
2025-11-21
Publication Date
2026-05-28

AI Technical Summary

Technical Problem

Existing laboratory-based assays for ferritin measurement are time-consuming, complex, require significant sample volumes, and costly, making them unsuitable for rapid diagnosis in point-of-care settings, while current biosensors lack robustness for routine clinical or veterinary use.

Method used

An electrochemical sensor using a sample activating composition with a reducing agent and complexing agent to detect and quantify biomolecules like ferritin, which is calibration-free and operates with reduced sample volumes, utilizing electrodes and electrical signal detection.

Benefits of technology

Provides a rapid, user-friendly, and reliable method for ferritin detection and quantification, suitable for point-of-care settings, enhancing clinical decision-making and reducing the burden of biomolecule-related disorders.

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Abstract

Described herein are methods and sensors for detecting a biomolecule analyte in a sample and uses related thereto. The sensor may utilise a substrate comprising a reference electrode, a counter electrode, and at least one working electrode; a sample activating composition in electrical contact with each of the electrodes and comprising a reducing agent and a complexing agent; and an electrical signal detector.
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