Insecticidal composition comprising chitin synthesis inhibitors

Abstract

The present invention provides a novel insecticidal composition of active compounds comprising Methoxyfenozide and Spinosyns and at least one further active compound selected from the class of chitin synthesis inhibitors, and to methods of controlling pests comprising applying said composition.

Description

[0001] INSECTICIDAL COMPOSITION COMPRISING CHITIN SYNTHESIS INHIBITORS

[0002] FIELD OF THE INVENTION

[0003] The present invention relates to novel insecticidal compositions of active compounds comprising Methoxyfenozide and Spinosyns and at least one further active compound selected from the class of chitin synthesis inhibitors, and to methods of controlling pests comprising applying said composition.

[0004] BACKGROUND OF THE INVENTION

[0005] In economically important crops, higher crop efficiency is achieved by controlling the invertebrate pests. Invertebrate pests cause damage to growing and stored agricultural crops and thereby result in significant reduction in the crop productivity. Therefore, the control of invertebrate pests is economically important for the enhanced crop productivity. Developing economically efficient and ecologically safe insecticidal composition and methods are an continuous requirement to broaden spectrum of control, to minimize the doses of chemicals used, to retard resistance development and to reduce the cost of the treatment through synergistic effect which is most sought properties of a combination products and highly unpredictable since the behaviour of each single insecticide in the combination is often affected by the presence of the other components and the activity of the mixture may also vary considerably depending on chemical character, plant species, growth stage, and environmental conditions.

[0006] Therefore, there exist a need in the art to develop a novel insecticidal composition, which are stable, synergistic, broad spectrum, environmentally safe and effective in control of a wide spectrum of insect pests in crops. The insecticidal compositions must show a broader scope of activity to avoid or to prevent the development of resistant varieties of strains to the active ingredients or to the mixtures of known active ingredients used by farmer while minimising the doses of chemicals sprayed in the agriculture fields.

[0007] As a solution to the above-mentioned problems, the inventors of the present invention surprisingly found that compositions comprising active compounds Methoxyfenozide and Spinosyns and at least one further active compound selected from the class of chitin synthesis inhibitors provides effective control of a wide spectrum of insect pests.

[0008] SUMMARY OF THE INVENTION Accordingly, the present invention provides a novel insecticidal composition of active compounds comprising Methoxy fenozi de and Spinosyns and at least one further active compound selected from the class of chitin synthesis inhibitors and agriculturally acceptable excipient(s).

[0009] In one aspect, the present invention provides a novel insecticidal composition of active compounds comprising Methoxy fenozi de and Spinosyns such as Spinosad and at least one further active compound selected from the class of chitin synthesis inhibitors such as Novaluron and Lufenuron and agriculturally acceptable excipient(s).

[0010] In one aspect, the present invention provides a novel insecticidal composition of active compounds comprising Methoxyfenozide and Spinosad and at least one further active compound selected from the class of chitin synthesis inhibitors such as Novaluron and Lufenuron and agriculturally acceptable excipient(s).

[0011] In one other aspect, the novel insecticidal composition of the present invention comprises Methoxyfenozide, Spinosad and Novaluron and agriculturally acceptable excipient(s).

[0012] In one other aspect, the novel insecticidal composition of the present invention comprises Methoxyfenozide, Spinosad and Lufenuron and agriculturally acceptable excipient(s).

[0013] In one aspect, the novel insecticidal compositions of the present invention may comprise Methoxyfenozide, Spinosad, Novaluron and Lufenuron in the form of agrochemically acceptable salts, esters or derivatives or any other suitable available form.

[0014] In one aspect, the novel insecticidal composition of the present invention comprises Methoxyfenozide in an amount in the range from 0.1-90% w / w; Spinosad in an amount in the range from 0.1-90% w / w; Novaluron in an amount in the range from 0.1-90% w / w and Lufenuron in an amount in the range from 0.1-90% w / w and agriculturally acceptable excipient(s).

[0015] In one other aspect, the novel insecticidal compositions of the present invention comprises Methoxyfenozide in an amount in the range from 10-65% w / w; Spinosad in an amount in the range from 1-25% w / w; Novaluron in an amount in the range from 2-30% w / w and Lufenuron in an amount in the range from 1-20% w / w and agriculturally acceptable excipient(s). In one another aspect, the novel insecticidal compositions of the present invention comprise Methoxyfenozide in an amount in the range from 16-60% w / w; Spinosad in an amount in the range from 6-20% w / w; Novaluron in an amount in the range from 7-25% w / w and Lufenuron in an amount in the range from 2-15% w / w and agriculturally acceptable excipient(s).

[0016] In one another aspect, the novel insecticidal compositions of the present invention comprise Methoxyfenozide in an amount in the range from 16-50% w / w; Spinosad in an amount in the range from 7-20% w / w; Novaluron in an amount in the range from 7-25% w / w and agriculturally acceptable excipient(s).

[0017] In one another aspect, the novel insecticidal compositions of the present invention comprise Methoxyfenozide in an amount in the range from 16-60% w / w; Spinosad in an amount in the range from 6-20% w / w; Lufenuron in an amount in the range from 2-15% w / w and agriculturally acceptable excipient(s).

[0018] In another aspect, the present invention provides a process of preparation of the novel insecticidal compositions comprising Methoxyfenozide, Spinosad and Novaluron or Lufenuron and agriculturally acceptable excipients.

[0019] In an aspect, the novel insecticidal composition of the present invention is formulated as Capsule suspension (CS), Dispersible concentrate (DC), Dustable powder (DP), Dry flowable (DF), Emulsifiable concentrate (EC), Emulsifiable granule (EG), Emulsion water-in-oil (EO), Emulsifiable powder (EP), Emulsion oil-in-water (EW), Granules (GR), Micro-emulsion (ME), Oil-dispersion (OD), Oil miscible flowable concentrate (OF), Oil miscible liquid (OL), Oil dispersible powder (OP), Suspension concentrate (SC), Suspension concentrate for direct application (SD), Suspo-emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Spreading oil (SO), Water soluble powder (SP), Ultra-low volume (ULV) suspension, Ultralow volume (ULV) liquid, Water dispersible granules (WDG / WG), Wettable powder (WP), a mixed formulation of CS and SC (ZC) or a mixed formulation of CS and SE (ZE), a mixed formulation of CS and EW (ZW) or any other formulation suitable for combinations.

[0020] In another aspect, the compositions of the present invention comprises one or more agriculturally acceptable excipient selected from the group comprising of dispersing agent(s), wetting agent(s), dispersing cum wetting agent(s), disintegrating agent(s), defoaming agent(s) / defoamer(s) / antifoaming agent(s) / antifoamer(s), biocide(s) / preservative(s), viscosity modifier(s) / rheology modifier(s) / thickener(s), anti-freeze agent(s), anti-caking agent(s), structuring agent(s), buffering agent(s), filler(s), diluent(s) or a combination thereof and other excipients as will be required in a particular type of formulation.

[0021] In another aspect, the compositions of the present invention comprises; the dispersing agent, is selected from the group comprising sodium salt of naphthalene sulfonate condensate, polycarboxylate sodium salt, kraft lignin polymer, alkyl polyethoxyethanol phosphate ester, proprietary blends of polycarboxylate, polymethyl methacrylate-polyethylene glycol graft copolymer, ethoxylated tri styrylphenol, tri styrylphenol phosphate, acrylate copolymer liquid dispersant, condensed methyl naphthalene sulfonate sodium salt, acrylate copolymer grafted with PEG, polyoxy ethylene alkyl aryl phosphate amine salt, poly-carboxylate dispersant, modified styrene acrylic polymeric dispersant, sodium lignosulphonate, modified sodium lignosulphonate or a combination thereof, and present in an amount in the range from 0.1 to 20% w / w; the wetting agent, is selected from the group comprising sodium isopropyl naphthalene sulfonate, sodium alkyl naphthalene sulfonate blend, polyoxyethylene alkyl ether, Adsee 2610 (non-ionic proprietary blend of supplier), polyalkylene oxide block copolymer, ethoxylated tristyrylphenol, sodium butyl naphthalene sulfonate, alkylaryl sulfonate, sodium alkyl dibutyl naphthalene sulfonate, dicotyl sulfosuccinate, sodium dioctyl sulphosuccinate, or a combination thereof and present in an amount in the range from 0.1-10% w / w; the disintegrating agent, is selected from the group comprising sodium sulfate anhydrous, ammonium sulfate, sodium chloride or a combination thereof and present in an amount in the range from 2-10% w / w the anti-freeze agent, is selected from the group comprising glycerol, propylene glycol, diethylene glycol, monoethylene glycol, urea, sodium chloride, magnesium heptahydrate or a combination thereof and present in an amount in the range from 1 to 10% w / w; the antifoam er / defoam er, is selected from the group comprising polydimethyl siloxane antifoam emulsion, powdered silicone antifoam, silicon antifoam emulsion, silicon emulsion, polysiloxane emulsion or a combination thereof and present in an amount in the range from 0.01 to 2% w / w; the biocide / preservative, is selected from the group comprising 20% aqueous dipropylene glycol solution of 1, 2-benzisothiazolin-3-one, formaldehyde, isothiazolinone or a combination thereof and present in an amount in the range from 0.01 to 1% w / w; the thickener, is selected from the group comprising xanthan gum, welan gum, guar gum, polyvinyl alcohol, carboxymethylcellulose, polyvinylpyrrolidone, carboxyvinyl polymer, acrylic polymer, starch derivative, polysaccharide, high purity silica, white carbon or a combination thereof and present in an amount in the range from 0.1-5% w / w; the anticaking agent is selected from the group comprising precipitated silica, urea formaldehyde resin, organic bentonite, polyolefin particles, fumed silica or a combination thereof, and present in an amount in the range from 0.1 to 10% w / w; the structuring agent is selected from the group comprising attapulgite clay, bentonite clay, smectite clay, montmorillonite clay and present in an amount 0.1 to 10% w / w; the buffering agent is citric acid and present in an amount 0.01 to 5% w / w; the filler, is selected from the group comprising, silica, precipitated silica, sodium bicarbonate, china clay, methyl soyate, sodium sulphate, sodium lignosulphonate, lactose, lactose anhydrous, bentonite clay, kaolin, diatomaceous earth or a combination thereof and present in an amount quantity sufficient (q.s.) to make 100% w / w formulation; the diluent is demineralised water and present in an amount quantity sufficient (q.s.) to make 100% w / w formulation.

[0022] DETAILED DESCRIPTION OF THE INVENTION

[0023] The definitions provided herein for the terminologies used in the present disclosure are for illustrative purpose only and in no manner limit the scope of the present invention disclosed in the present disclosure.

[0024] Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by a person of ordinary skill in the art to which the invention pertains. Although other methods and materials similar, or equivalent, to those described herein can be used in the practice of the present invention, the preferred materials and methods are described herein.

[0025] It is to be noted that, as used in the specification and the appended claims, the singular forms "a", "an" and "the" include plural referents unless the context clearly dictates otherwise. Thus, for example, reference to a composition containing “a compound” includes a mixture of two or more compounds. It should also be noted that the term “or” is generally employed in its sense including “and / or” unless the content clearly dictates otherwise.

[0026] As used herein, the terms "comprises", "comprising", "includes", "including", “has”, “having”, “contains”, “containing”, “characterized by” or any other variation thereof, are intended to cover a non-exclusive inclusion, subject to any limitation explicitly indicated. For example, a composition, mixture, process or a method that comprises a list of elements is not necessarily limited to only those elements but may include other elements not expressly listed or inherent to such composition, mixture, process or method.

[0027] The transitional phrase “consisting of’ excludes any element, step or ingredient not specified. If in the claim, such would close the claim to the inclusion of materials other than those recited except for impurities ordinarily associated therewith. When the phrase “consisting of’ appears in a clause of the body of a claim, rather than immediately following the preamble, it limits only the element set forth in that clause; other elements are not excluded from the claim as a whole.

[0028] As used herein, the terms “composition” or “compositions” or "formulation" or "formulations" can be used interchangeably, unless stated otherwise, is meant to encompass, and are not limited to, compositions or formulations containing the combination of Methoxyfenozide and Spinosad and at least one further active compound selected from the class of chitin synthesis inhibitors such as Novaluron and Lufenuron.

[0029] As used herein, the term “agriculturally acceptable excipient (s)” refers to inert substances and are auxiliary substances added to the processing or use of pesticide preparations and used to improve the physical and chemical properties of formulations. The auxiliaries themselves are essentially free of biological activity, but can affect the control effect. The expression of various quantities in terms of “% w / w” or “%” means the percentage by weight, relative to the weight of the total solute on or composition unless otherwise specified.

[0030] The term “active ingredient” (a.i.) or “active agent” used herein refers to that component of the composition responsible for control of insects-pests in crops of useful plants.

[0031] As used herein, the term "effective amount" means the amount of the active substances in the compositions to achieve an observable effect on death, retardation, prevention, and removal, destruction, or otherwise diminishing the occurrence and activity of the target pests. An effective amount of the compositions will also vary according to the prevailing conditions such as desired insecticidal effect and duration, weather, target pests and species, target crops, locus, mode of application, and the like.

[0032] As used herein, the term “insecticide”, refers to any chemical substance used to destroy / kill, inhibit or otherwise adversely affect the insect pests.

[0033] As used herein, the term “Methoxy fenozi de” encompasses its agrochemically acceptable salt(s), derivative(s) or any other modified form of Methoxyfenozide. It belongs to the class of diacylhydrazine insecticide. It acts by lethally accelerating the moulting process, it is primarily active by ingestion, also with some contact and ovicidal activity.

[0034] As used herein, the term “Spinosyns” represents a family of broad-spectrum of insecticides including spinosad and spinetoram, all with a macrocyclic lactone structure, isolated from the actinomycete soil bacterium Saccharopolyspora spinosa. The spinosyns have a novel mode of action, primarily targeting binding sites on nicotinic acetylcholine receptors (nAChRs) of the insect nervous system that are distinct from those at which other insecticides have their activity. Spinosyns have been used around the world for the control of a variety of insect pests, including Lepidoptera, Diptera, Thysanoptera, Coleoptera, Orthoptera, and Hymenoptera, and many others including Thrips.

[0035] As used herein, the term “chitin synthesis inhibitors” (CSIs) are a class of insect growth regulators (IGRs) that prevent insects from molting by interfering with chitin formation and effective against the adults, eggs and larvae of this insect. Chemically “chitin synthesis inhibitors” belongs to Benzoylurea class of chemicals and widely used in integrated pest management (IPM) and insecticide resistance management (IRM) programs due to their low toxicity to mammals and predatory insects. In the past decades, a large number of Benzoylurea derivatives have been synthesized, among them are Bistrifluron, Chlorbenzuron, Chlorfluazuron, Dichlorbenzuron, Diflubenzuron, Flucycloxuron, Flufenoxuron, Hexaflumuron, Lufenuron, Novaluron, Noviflumuron, Penfluron, Ttriflumuron and Tefl benzuron.

[0036] In an embodiment, the present invention provides a novel insecticidal composition of active compounds comprising Methoxy fenozi de and Spinosyns and at least one further active compound selected from the class of chitin synthesis inhibitors and agriculturally acceptable excipient(s).

[0037] In an embodiment, the present invention provides a novel insecticidal composition of active compounds comprising Methoxy fenozi de and Spinosyns such as Spinosad and at least one further active compound selected from the class of chitin synthesis inhibitors such as Novaluron and Lufenuron and agriculturally acceptable excipient(s).

[0038] In an embodiment, the present invention provides a novel insecticidal composition of active compounds comprising Methoxyfenozide and Spinosad and at least one further active compound selected from the class of chitin synthesis inhibitors such as Novaluron and Lufenuron and agriculturally acceptable excipient(s).

[0039] In an embodiment, the novel insecticidal composition of the present invention comprise Methoxyfenozide in an amount in the range from 0.1-90% w / w; Spinosad in an amount in the range from 0.1-90% w / w; Novaluron in an amount in the range from 0.1-90% w / w and Lufenuron in an amount in the range from 0.1-90% w / w and agriculturally acceptable excipient(s).

[0040] In an embodiment, the novel insecticidal compositions of the present invention comprise Methoxyfenozide in an amount in the range from 10-65% w / w; Spinosad in an amount in the range from 1-25% w / w; Novaluron in an amount in the range from 2-30% w / w and Lufenuron in an amount in the range from 1-20% w / w and agriculturally acceptable excipient(s).

[0041] In an embodiment, the novel insecticidal compositions of the present invention comprise Methoxyfenozide in an amount in the range from 16-60% w / w; Spinosad in an amount in the range from 6-20% w / w; Novaluron in an amount in the range from 7-25% w / w and Lufenuron in an amount in the range from 2-15% w / w and agriculturally acceptable excipient(s).

[0042] In an embodiment, the novel insecticidal compositions of the present invention comprise Methoxyfenozide in an amount in the range from 16-50% w / w; Spinosad in an amount in the range from 7-20% w / w; Novaluron in an amount in the range from 7-25% w / w and agriculturally acceptable excipient(s).

[0043] In an embodiment, the novel insecticidal compositions of the present invention comprise Methoxyfenozide in an amount in the range from 16-60% w / w; Spinosad in an amount in the range from 6-20% w / w; Lufenuron in an amount in the range from 2-15% w / w and agriculturally acceptable excipient(s).

[0044] In another embodiment, the novel insecticidal composition of the present invention is formulated as Capsule suspension (CS), Dispersible concentrate (DC), Dry flowable (DF), Dustable powder (DP), Emulsifiable concentrate (EC), Emulsifiable granule (EG), Emulsion water-in-oil (EO), Emulsifiable powder (EP), Emulsion oil-in-water (EW), Granules (GR), Micro-emulsion (ME), Oil -dispersion (OD), Oil miscible flowable concentrate (OF), Oil miscible liquid (OL), Oil dispersible powder (OP), Suspension concentrate (SC), Suspension concentrate for direct application (SD), Suspo-emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Spreading oil (SO), Water soluble powder (SP), Ultra-low volume (ULV) suspension, Ultra-low volume (ULV) liquid, Water dispersible granules (WDG / WG), Wettable powder (WP), a mixed formulation of CS and SC (ZC) or a mixed formulation of CS and SE (ZE), a mixed formulation of CS and EW (ZW) or any other formulation suitable for combinations.

[0045] In one another embodiment, the compositions of the present invention comprises one or more agriculturally acceptable excipient selected from the group comprising of dispersing agent(s), wetting agent(s), dispersing cum wetting agent(s), disintegrating agent(s), defoaming agent(s) / defoamer(s) / antifoaming agent(s) / antifoamer(s), biocide(s) / preservative(s), viscosity modifier(s) / rheology modifier(s) / thickener(s), anti-freeze agent(s), anti-caking agent(s), structuring agent(s), buffering agent(s), filler(s), diluent(s) or a combination thereof and other excipients as will be required in a particular type of formulation. The compositions of present invention uses dispersing agents to prevent agglomeration of solid particles and keep them suspended in fluid. Non-limiting examples of dispersing agent that can be used in the present invention include, but not limited to ethoxylated Polyarylphenol Phosphate Amine salt, polymethyl methacrylate-polyethylene oxide graft copolymer, graft copolymer of polymethyl methacrylate-polyethylene glycol, sodium salt of naphthalene sulfonate condensate, polycarboxylate sodium salt, ethoxylated isodecyl alcohol, blend of acrylic graft copolymer and emulsifier, tri styrylphenol ethoxylate, tri styrylphenol phosphate, anionic tri styrylphenol phosphate surfactant, non-ionic surfactant, polyalkoxylated butyl ether dispersant, sodium alkylnaphthalene sulfonate condensate, sodium lignosulphonate, sodium naphthalene sulphonate salt, sodium alkylnaphthalene sulfonate phenol condensate, sodium alkylnaphthalene sulfonate formaldehyde condensate, sodium polycarboxylate, modified styrene acrylic polymeric dispersant, modified styrene acrylic polymeric aqueous dispersant, proprietary blend of phosphate ester and sodium naphthalene sulphate formaldehyde condensate, kraft lignin polymer, lignosulfonic acid dispersant, kraft lignosulfonate with a low degree sulfonation, modified sodium lignosulphonate, polymethyl methacrylate-polyethylene glycol graft copolymer, ethoxylated tristyrylphenol, naphthalene sulfonate formaldehyde condensate, mixture of salt of naphthalene sulphonic acid and phenol, alkyl naphthalene sulfonate sodium salt, modified sodium lignosulphonate, modified naphthalene sulfonate formaldehyde condensate, highly sulfonated kraft lignin, naphthalene sulfonate phenol condensate, sodium isopropyl naphthalene sulfonate. One or more dispersing agents may be used in the compositions of the present invention. The dispersing agent is present in the range from 0.1-20% w / w.

[0046] The compositions of present invention uses wetting agent to facilitate the process of dispersion of the granules in the liquid. Non-limiting examples of wetting agents that can be used in the present invention include, but not limited to alkylaryl sulfonate, sodium alkyl dibutyl naphthalene sulfonate, branched short chain alcohol ethoxylate wetter, sodium alkyl naphthalene sulfonate with an anionic blend, polyalkylene glycol ether, EO / PO block copolymer, polyoxyethylene alkyl ether wetter, sodium alkyl naphthalene sulfonate blend, sodium alkyl naphthalene sulfonate blend with a anionic blend, nonionic proprietary surfactant blend, sulphonated anionic wetter, copolymer condensate of ethylene and propylene oxide, ethoxylated isodecyl alcohol, sodium alkyl naphthalene sulfonate formaldehyde condensate, comb-type polymeric surfactant, polyalkylene oxide block copolymer, dicotyl sulfosuccinate, sodium dioctyl sulphosuccinate, ethoxylated polyarylphenol phosphate amine salt, sodium isopropyl naphthalene sulfonate, dibutyl naphthalene sulfonic acid sodium salt, dialkyl naphthalene sulphonate, sodium dioctyl sulfosuccinate. One or more wetting agents may be used in the compositions of the present invention. The wetting agents is present in the range from 0.1-10% w / w.

[0047] The compositions of present invention also uses disintegrating agent that can swell or disintegrate the composition. Non-limiting examples of disintegrating agent that can be used in the present invention include, but not limited to, ammonium sulphate, sodium sulfate anhydrous, lactose, sodium chloride. One or more disintegrating agent may be used in the compositions of the present invention. Disintegrating agent is present in the range from 2-10% w / w.

[0048] The compositions of present invention uses anti-freeze agent which are used to prevent deleterious effects due to freezing and lyophilization (lyophilisation). Suitable anti-freeze agent used herein, but not limited to glycerol, propylene glycol, diethylene glycol, monoethylene glycol, urea, sodium chloride, magnesium heptahydrate or a combination thereof and present in the range from 1 to 10% w / w.

[0049] The composition of present invention also uses defoaming agent. The term “defoaming agent(s)” or “defoamer(s)” or “antifoaming agent(s)” “antifoamer(s)” refers to a chemical additive that reduces and hinders the formation of foam in liquid, semi-solid, or solid formulations. The terms defoaming agent and anti-foaming agent can be used interchangeably. Suitable defoamer used herein, but not limited to, polydimethylsiloxane antifoam emulsion, silicon emulsion, powdered silicone antifoam, silicon antifoam emulsion, silicon emulsion, poly siloxane emulsion, organic fluorine compounds. One or more defoaming agent may be used in the compositions of the present invention. Defoaming agent is present in the range from 0.01 to 2% w / w.

[0050] The compositions of present invention uses biocide / preservatives to prevent the composition from spoilage due to bacteria, yeasts and fungi or deterioration due to undesirable chemical changes. Suitable biocide / preservative used herein, but not limited to 20% aqueous dipropylene glycol solution of 1, 2-benzisothiazolin-3-one, formaldehyde, potassium sorbate, 4- hydroxybenzoic acid esters, 2-methyl-4-isothiazolin-3-one, 5-chloro-2-methyl-4-isothiazolin- 3-one or a combination thereof and present in the range from 0.01-1% w / w. The compositions of present invention uses thickener which are usually polymeric material, and at a low concentration increases the viscosity of an aqueous solution and helps to stabilize the composition. Suitable thickener used herein, but not limited to xanthan gum, welan gum, guar gum, polyvinyl alcohol, carboxymethylcellulose, polyvinylpyrrolidone, carboxyvinyl polymer, acrylic polymer, starch derivative, polysaccharide, high purity silica, white carbon or a combination thereof and present in the range from 0.1-5% w / w. the anticaking agent is selected from the group comprising precipitated silica, urea formaldehyde resin, organic bentonite, polyolefin particles, fumed silica or a combination thereof, and present in an amount in the range from 0.1 to 10% w / w;

[0051] The compositions of present invention use structuring agent which are used to manage the phase separation of layer and two phases in suspension concentrate, water and material remains in suspending form and do not get settled down at bottom during shelflife. Suitable structuring agent used herein, but not limited to attapulgite clay, bentonite clay, smectite clay, montmorillonite clay and present in an amount 0.1 to 10% w / w; the buffering agent is citric acid and present in an amount 0.01 to 5% w / w;

[0052] The compositions of present invention uses filler. Suitable fillers that may be used in the compositions of the present invention include, but not limited to, silica, precipitated silica, sodium bicarbonate, china clay, methyl soyate, sodium sulphate, sodium lignosulphonate, lactose anhydrous lactose, bentonite clay, kaolin, diatomaceous earth. The filler may be used in an amount of quantity sufficient to make 100%w / w formulation.

[0053] The compositions of present invention uses diluents. Suitable diluents that may be used in the composition of the present invention is demineralised water and present in an amount quantity sufficient to make 100%w / w formulation.

[0054] In an embodiment, the present invention provides a process for the preparation of a wettable powder (WP) formulation which comprises: a) weighing and mixing of required active ingredients and other ingredients using proper ribbon blender type mixer till homogenous material obtained; b) milling in a suitable air jet mill; c) grinding the material to obtain desired particle size (D90- <10 micron); d) blending in a post blender and e) mixing homogeneously to obtain the wettable powder formulation. In an embodiment, the present invention provides a process for the preparation of a water dispersible granules (WDG / WG) formulation which comprises: a) weighing and mixing of required active ingredients and other ingredients using proper ribbon blender type mixer till homogenous material obtained; b) milling in a suitable air jet mill; c) grinding the material to obtain desired particle size (D90- <10 micron); d) blending in a post blender; e) preparing dough of fine milled powder in dough maker machine with addition of suitable quantity of water and defoamer; f) extruding the granules of prepared dough using extruder machine having suitable screen; and g) drying the extruded granules using a Fluid Bed Dryer while maintaining at temperature 50°C to obtain water dispersible granules formulation.

[0055] In an embodiment, the present invention provides a process for the preparation of a dry flowable (DF) formulation which comprises: a) weighing and mixing of required active ingredients and other ingredients including water; b) mixing well using proper reactor till homogeneous blend obtained; c) milling the premix using suitable bead mill; d) grinding the material to obtain desired particle size (D90- <10 micron); e) blending the slurry in a post reactor; f) spray drying the slurry using spray dryer and removing the additional water used during bead milling and premixing; and g) drying the granules using a Fluid Bed Dryer while maintaining at temperature 50°C to obtain dry flowable formulation.

[0056] In an embodiment, the present invention provides a process for the preparation of a suspension concentrate (SC) formulations which comprises: a) preparing 2% gum solution using thickener and biocide in distilled water with high shear mixing and keep it for 24 hours aside; b) adding diluent, buffering agent, defoamer and anti-freezing agent in a mixing vessel; c) adding dispersing agent, wetting agents and structuring agent in step b) material under stirring condition; d) mixing till homogeneous mixture obtained; e) adding active ingredients in step d) material and mixing with high speed homogenizer (1000-1200 rpm) till homogeneous slurry obtained (approx. 15-20 min.); f) wet grinding the homogeneous slurry using bead mill till desired particle size (D90- <10pm) obtained while maintaining temperature in the range of 20°C to 25°C; g) withdrawing material od step f) and giving water wash with remaining quantity of water; h) withdrawing washed material in the same container and mix it well with overhead stirrer; i) adding previously prepared thickener solution (2%) of step a) into above milled material and stirred with low shear mixing stirrer till thickener uniformly distribute to obtain homogeneous mixture of suspension concentration formulation. The compositions of the present invention is found to be effective to control wide spectrum of insect pests from the orders of Lepidoptera, Thysanoptera, Diptera, Hemiptera, particularly the compositions of present invention gave excellent control on Thrips, Fruit Borer, Pod Borer, American Bollworms, Leaf Minor, Spodoptera, Fall Armyworm, Diamond Back Moth (DBM), Loopers, Leaf rollers, Moth, Stem Borer, Citrus Leaf Minor, Psyllid, Fruit and Shoot Borer, Early Shoot Borer, Podfly, Western flower thrips, Leaf folder, Psyllid, Top Shoot borer. Further the compositions of the present invention may be used to control variety of insect pests in Cotton, Chilli, Soybean, Bengal gram, Redgram, Tomato, Brinjal, Rice, Pomegranate, Vegetables, Cabbage, Cauliflowers, Corn, Citrus, Sugarcane, Groundnut, particularly the compositions of present invention tested on vegetables viz., chilli and cotton crops and gave significantly better results compared to solo and binary compositions.

[0057] The compositions of the present invention can be applied by any one of the methods selected from atomization, spreading, dusting, spraying, diffusion, immersion, irrigation (chemigation), mixing, foaming, dressing, coating, blasting, fumigation, smoking, smog and painting.

[0058] The rate of application amount of the prepared compositions varies depending on, for example, the blending ratio of active ingredients, meteorological condition, dosage form, application time, application method, application place, insects to be controlled, and a target crop, in ordinary cases.

[0059] The inventors of the present invention have surprisingly found that the compositions of the present invention showed enhanced control over existing compositions. Moreover, the composition of the present invention is more effective than their individual counterparts. This allows a substantial reduction in the application rates of each of these active ingredients, while maintaining good efficacy. The decrease in application rates reduces treatment cost to the farmer and also eases the burden on the environment both from manufacturing waste and crop protection chemical residues.

[0060] The insecticidal compositions of present invention provide a wide spectrum control of insectpests, delays the emergence of the resistant strains, minimizes the risk of development of resistance and achieves effective and economical control of undesired insect-pest.

[0061] The insecticidal compositions of present invention provide a wide spectrum control of insectpests and minimizes the risk of development of resistance ultimately, which reflects the delays in emergence of the resistant strains hence provide effective and economical control of undesired insect-pest.

[0062] The insecticidal compositions of the present invention provide a number of other advantages:

[0063] • Significant increased efficacy in comparison to the other formulations tested during the trials.

[0064] • Is synergistic hence denies the need of sequential application of solo insecticides to control different pest spectra thereby reducing the environmental load of insecticides.

[0065] • Uses lesser amounts of active ingredients hence considerable reduction in cost, which would benefit farmers.

[0066] • The compositions provided one shot solution to farmers to control broad spectrum of pests.

[0067] • Is storage stable.

[0068] • Is completely safer to crops (non-phytotoxic).

[0069] • Reduction in environmental load of insecticidal residues.

[0070] • Reduction in quantity of water required for spray of the product in agriculture fields.

[0071] • Reduction in generation of empty containers of product, thereby, reducing concerns of their disposal.

[0072] • Provides a broad range of product choice for effective pest management.

[0073] Thus, from the foregoing description, it will be apparent to one of the person skilled in the art that many changes and modifications can be made thereto without departing from the scope of the invention as set forth in the description. Accordingly, it is not intended that the scope of the foregoing description be limited to the description set forth above, but rather that such description be construed as encompassing such features that reside in the present invention, including all the features and embodiments that would be treated as equivalents thereof by those skilled in the relevant art.

[0074] The embodiments of the present invention are more particularly described in the following examples that are intended as illustrations only, since numerous modifications and variations within the scope of the present invention will be apparent to those of skill in the art. Unless otherwise noted, all parts, percentages and ratios reported in the following examples are on a weight basis and all reagents used in the examples were obtained or are available from the chemical suppliers. EXAMPLES

[0075] The insecticidal compositions of the present invention comprising Methoxyfenozide and Spinosad and at least one further active compound selected from the class of chitin synthesis inhibitors such as Novaluron and Lufenuron and agriculturally acceptable excipient(s) in the form of wettable powder (WP) formulation, water dispersible granule (WDG / WG) formulation, dry flowable (DF) formulation and suspension concentrate (SC) formulation and is provided in table 1-32. The unit of each component of the compositions are expressed in “% w / w” i.e. the percentage by weight, relative to the weight of the total solution or composition. All the compositions are prepared by following the processes as disclosed in description. All the prepared compositions of the present invention have been tested for stability / shelf life at accelerated temperature.

[0076] Table 1: Examples 1 to 4: Compositions of Methoxyfenozide + Spinosad + Novaluron (WP)

[0077] QS: quantity sufficient required to make 100% w / w formulation

[0078] Process of preparing novel insecticidal composition comprising Methoxyfenozide, Spinosad and Novaluron (WP): Table 2 provides quantities of active ingredients and raw material charged to prepare the novel insecticidal composition of the present invention in WP form which comprises: a) weighing and mixing of required active ingredients and other ingredients using proper ribbon blender type mixer till homogenous material obtained; b) milling in a suitable air jet mill; c) grinding the material to obtain desired particle size (D90- <10 micron); d) blending in a post blender and e) mixing homogeneously to obtain the wettable powder formulation.

[0079] Table 2: Quantities of ingredients in gram charged to prepare the compositions of Eg 1 and 4 of table 1

[0080] Table 3: Stability studies of the composition of Eg 1 of table 2 (Shelflife based on accelerated storage at 54 ± 2°C) Table 4: Stability studies of the composition of Eg 4 of table 2. (Shelflife based on accelerated storage at 54 ± 2°C) Table 5: Examples 5 to 8: Compositions of Methoxyfenozide + Spinosad + Novaluron (WG)

[0081] Process of preparing novel insecticidal composition comprising Methoxyfenozide, Spinosad and Novaluron (WG):Table 6 provides quantities of active ingredients and raw material charged to prepare the novel insecticidal composition of the present invention in WG form which comprises: a) weighing and mixing of required active ingredients and other ingredients using proper ribbon blender type mixer till homogenous material obtained; b) milling in a suitable air jet mill; c) grinding the material to obtain desired particle size (D90- <10 micron); d) blending in a post blender; e) preparing dough of fine milled powder in dough maker machine with addition of suitable quantity of water and defoamer; f) extruding the granules of prepared dough using extruder machine having suitable screen; and g) drying the extruded granules using a Fluid Bed Dryer while maintaining at temperature 50°C to obtain water dispersible granules formulation.

[0082] Table 6: Quantities of ingredients in gram charged to prepare the compositions of Eg 5 and 6 of table 5

[0083] Table 7: Stability studies of the composition of Eg 5 of table 6 (Shelflife based on accelerated storage at 54 ± 2°C)

[0084] Table 8: Stability studies of the composition of Eg 6 of table 6 (Shelflife based on accelerated storage at 54 ± 2°C)

[0085] Table 9: Examples 9 to 12: Compositions of Methoxyfenozide + Spinosad + Novaluron (DF)

[0086] Process of preparing novel insecticidal composition comprising Methoxyfenozide, Spinosad and Novaluron (DF): Table 10 provides quantities of active ingredients and raw material charged to prepare the novel insecticidal composition of the present invention in DF form which comprises: a) weighing and mixing of required active ingredients and other ingredients including water; b) mixing well using proper reactor till homogeneous blend obtained; c) milling the premix using suitable bead mill; d) grinding the material to obtain desired particle size (D90- <10 micron); e) blending the slurry in a post reactor; f) spray drying the slurry using spray dryer and removing the additional water used during bead milling and premixing; and g) drying the granules using a Fluid Bed Dryer while maintaining at temperature 50°C to obtain dry flowable formulation.

[0087] Table 10: Quantities of ingredients in gram charged to prepare the compositions of Eg 9 and 11 of table 9

[0088] Table 11: Stability studies of the composition of Eg 9 of table 10 (Shelf life based on accelerated storage at 54 ± 2°C)

[0089]

[0090] Table 12: Stability studies of the composition of Eg 11 of table 10 (Shelf life based on accelerated storage at 54 ± 2°C)

[0091] Table 13: Examples 13 to 14: Compositions of Methoxyfenozide + Spinosad + Novaluron (SC)

[0092] Process of preparing novel insecticidal composition comprising Methoxyfenozide + Spinosad+ Novaluron (SC): Table 14 provides quantities of active ingredients and raw material charged to prepare the novel insecticidal composition of the present invention in SC form which comprises: a) preparing 2% gum solution using thickener and biocide in distilled water with high shear mixing and keep it for 24 hours aside; b) adding diluent, buffering agent, defoamer and anti-freezing agent in a mixing vessel; c) adding dispersing agent, wetting agents and structuring agent in step b) material under stirring condition; d) mixing till homogeneous mixture obtained; e) adding active ingredients in step d) material and mixing with high speed homogenizer (1000-1200 rpm) till homogeneous slurry obtained (approx. 15-20 min.); f) wet grinding the homogeneous slurry using bead mill till desired particle size (D90- <10pm) obtained while maintaining temperature in the range of 20°C to 25°C; g) withdrawing material od step f) and giving water wash with remaining quantity of water; h) withdrawing washed material in the same container and mix it well with overhead stirrer; i) adding previously prepared thickener solution (2%) of step a) into above milled material and stirred with low shear mixing stirrer till thickener uniformly distribute to obtain homogeneous mixture of suspension concentration formulation.

[0093] Table 14: Quantities of ingredients in gram charged to prepare the compositions of Eg 13 and 14 of table 13

[0094] Table 15: Stability studies of the composition of Eg 13 of table 14 (Shelf life based on accelerated storage at 54 ± 2°C)

[0095] Table 16: Stability studies of the composition of Eg 14 of table 14 (Shelf life based on accelerated storage at 54 ± 2°C)

[0096] Table 17: Examples 15 to 19: Compositions of Methoxyfenozide + Spinosad + Lufenuron (WP)

[0097] Process of preparing novel insecticidal composition comprising Methoxyfenozide, Spinosad and Lufenuron (WP): Table 18 provides quantities of active ingredients and raw material charged to prepare the novel insecticidal composition of the present invention in WP form. The process methodology of preparation is same as described for table 2.

[0098] Table 18: Quantities of ingredients in gram charged to prepare the compositions of Eg 15 of table 17

[0099] Table 19: Stability studies of the composition of Eg 15 of table 18 (Shelf life based on accelerated storage at 54 ± 2°C)

[0100] Table 20: Examples 20 to 24: Compositions of Methoxyfenozide + Spinosad + Lufenuron (WG)

[0101] Process of preparing novel insecticidal composition comprising Methoxyfenozide, Spinosad and Lufenuron (SC): Table 21 provides quantities of active ingredients and raw material charged to prepare the novel insecticidal composition of the present invention in SC form. The process methodology of preparation is same as described for table 6.

[0102] Table 21: Quantities of ingredients in gram charged to prepare the compositions of Eg 20 and 21 of table 20

[0103] Table 22: Stability studies of the composition of Eg 20 of table 21 (Shelf life based on accelerated storage at 54 ± 2°C)

[0104]

[0105] Table 23: Stability studies of the composition of Eg 21 of table 21 (Shelf life based on accelerated storage at 54 ± 2°C)

[0106] Table 24: Examples 25 to 29: Compositions of Methoxyfenozide + Spinosad + Lufenuron (DF)

[0107] Process of preparing novel insecticidal composition comprising Methoxyfenozide, Spinosad and Lufenuron (DF): Table 25 provides quantities of active ingredients and raw material charged to prepare the novel insecticidal composition of the present invention in DF form. The process methodology of preparation is same as described for table 10.

[0108] Table 25: Quantities of ingredients in gram charged to prepare the compositions of Eg 25 and 29 of table 24

[0109] Table 26: Stability studies of the composition of Eg 25 of table 25 (Shelf life based on accelerated storage at 54 ± 2°C)

[0110]

[0111] Table 27: Stability studies of the composition of Eg 29 of table 25 (Shelf life based on accelerated storage at 54 ± 2°C)

[0112] Table 28: Examples 30 to 32: Compositions of Methoxyfenozide + Spinosad + Lufenuron (SC)

[0113] Process of preparing novel insecticidal composition comprising Methoxyfenozide, Spinosad and Lufenuron (SC): Table 29 provides quantities of active ingredients and raw material charged to prepare the novel insecticidal composition of the present invention in SC form. The process methodology of preparation is same as described for table 14.

[0114] Table 29: Quantities of ingredients in gram charged to prepare the compositions of Eg 30, 31 and 32 of table 28

[0115] Table 30: Stability studies of the composition of Eg 30 of table 25 (Shelf life based on accelerated storage at 54 ± 2°C)

[0116] Table 31: Stability studies of the composition of Eg 31 of table 25 (Shelf life based on accelerated storage at 54 ± 2°C)

[0117] Table 32: Stability studies of the composition of Eg 32 of table 25 (Shelf life based on accelerated storage at 54 ± 2°C)

[0118] As evident from the foregoing tables (1-32) that all the desired compositions have been prepared successfully and has been tested for stability / shelf life at accelerated temperature. After 14 days of storage at 54.0 ± 2 °C, there were no significant changes in active ingredient content, suspensibility, wettability, dispersibility, pH and has passes the sieve test. Therefore, it is concluded that compositions of present invention have good stability and shelf life.

[0119] BIO-EFFICACY OF THE INSECTICIDAL COMPOSITIONS OF THE PRESENT INVENTION

[0120] Experimental trial was conducted to evaluate the insecticidal compositions of the present invention in India against major insects on Chilli and Cotton Crop with ternary compositions of present invention and comparative solo and binary compositions as per the details provided in Table 33-48. The abbreviations used in table 33-48 are as follows:

[0121] TN: Treatment Number

[0122] ROC: Reduction Over Control g.a.i: gram active ingredients ha: hectare

[0123] DAA: Days after Insecticide application

[0124] O=Observed % insect reduction (%) Calculated using Abbott Formula;

[0125] E=Expected % insect reduction Calculated using Colby Formula;

[0126] CR=Colby ratio

[0127] UTC: Untreated control

[0128] Experimental design and method for Chilli Crop

[0129] The present field experiment was conducted at Baptala of Guntur district of Andhra Pradesh state in India during the season Rabi-2024-25 with thirty-five treatments + One control treatment replicated thrice in randomized block design. The popular and widely cultivated Guntur Chilli variety S-4 selected for this experiment was sown in a plot size of 5m X 5m for each replication with a spacing of 60 cm X 45cm in sandy loam soil. The crop was maintained well by adapting standard agronomic practices. The treatments were imposed when thrips population and fruit borer attained economic threshold level as single directed application. The observations on counts of thrips population were recorded from top, middle and bottom leaves from five randomly tagged plants whereas the larval population of fruit borer was recorded per plant from five randomly tagged plants per plot. Insect observation were taken at (0 day) before spray and post treatment counts were made at 7 and 14 days after application (DAA) and presented as mean reduction over Control (% ROC). The application was carried out by using the hand operated aspire Knapsack sprayer pump fitted with hollow cone nozzle. The required quantity of water volume was used @ 500 litre per hectare.

[0130] The % reduction in target insect population over control was calculated by using Abbott's formula: Reference: Abbott, W.S. (1925). A method of computing the effectiveness of an insecticide. J. Econ. Entomol.; 18: 265-267. n in T after treatment

[0131] Corrected % Insect Reduction= 1- X 100 n in Co after treatment

[0132] Where, n = no. of insects; T = Treated; Co = Control

[0133] The percent increase yield over control was calculated by using following formula:

[0134] Yield in treated plot- Yield in control plot

[0135] Percent increase yield = x 100

[0136] Yield in control plot

[0137] Experimental design and method for Cotton Crop

[0138] The present field experiment was conducted in Akola district of Maharashtra state in India during the season Kharif-2024 with thirty-five treatments + One control treatment replicated thrice in randomized block design. The Cotton hybrid Surpass Super was sown in a plot size of 5.4m X 5.4m for each replication with a spacing of 90cm X 60cm in black Cotton soil. The crop was maintained well by adapting standard agronomic practices. The treatments were imposed when thrips and bollworm population attained economic threshold level as single directed application. The populations of thrips were recorded from top, middle and bottom leaves from five randomly tagged plants whereas the larval population of bollworms were recorded per plant from five randomly tagged plants per plot at a day (0 day) before spray and 7 and 14 days after application (DAA) and presented as mean reduction over control (% ROC). The applications were carried out by using the hand operated aspire Knapsack sprayer pump fitted with hollow cone nozzle. The required quantity of water volume was used @ 500 litre per hectare. The % reduction in target insect population over control was calculated by using Abbott's formula as given above. The percent increase yield over control was calculated by using following formula as given above. Phytotoxicity Observations: The phytotoxicity data were recorded at 1 DAA, 7 DAA and 14 DAA after application as per phytotoxicity rating scale (0-10) on phytotoxicity parameters i.e. Epinasty, Hyponasty, Necrosis, Vein clearing and Wilting etc. Insecticidal combinations of the present invention were found completely safe (non-phytotoxic) on tested crops.

[0139] Evaluation of synergistic effect

[0140] A synergistic effect exists whenever the action of an active ingredient combination is greater than the sum of the actions of the individual components. Synergism was calculated by using Colby’s method, Weeds, vol. 15 No. l(Jan 1967), pp. 20-2.

[0141] The synergistic action expected for a given combination of two active components can be calculated as follows:

[0142] The synergistic action expected for a given combination of three active components can be calculated as follows:

[0143] (XY+YZ+XZ) XYZ

[0144] E=(X+Y+Z)

[0145] 100+10000

[0146] Where:

[0147] E represents expected percentage of control for the combination of the three active ingredients at defined doses (for example equal to x, y and z respectively),

[0148] X is the percentage of control observed by the compound (I) at a defined dose (equal to x),

[0149] Y is the percentage of control observed by the compound (II) at a defined dose (equal to y),

[0150] Z is the percentage of control observed by the compound (III) at a defined dose (equal to z).

[0151] If observed control of the combination > Expected control, the combination is synergistic (Colby ratio > 1)

[0152] If observed control of the combination < Expected control, the combination is antagonistic (Colby ratio < 1)

[0153] If observed control of the combination = Expected control, the combination is additive (Colby ratio =1)

[0154] Table 33: Efficacy of Insecticidal Composition Methoxyfenozide + Spinosad + Novaluron on Chilli Crop against fruit borer

[0155] Table 34: Efficacy of Insecticidal Composition Methoxyfenozide + Spinosad + Novaluron on Chilli Crop against Thrips.

[0156] Table 35: Effect on yield of Insecticidal Composition Methoxyfenozide + Spinosad + Novaluron on Chilli Crop

[0157] Table 36: Phytotoxic effect of Insecticidal Composition Methoxyfenozide + Spinosad + Novaluron of the present invention on Chilli crop

[0158] | TN | Treatments Detail | Dose | Phytotoxicity observations at 1 PAA, 7 PAA & 14 PAA |

[0159]

[0160] Table 37: Efficacy of Insecticidal Composition Methoxyfenozide + Spinosad + Novaluron on Cotton Crop against Bollworms

[0161] Table 38: Efficacy of Insecticidal Composition Methoxyfenozide + Spinosad + Novaluron on Cotton Crop against Thrips

[0162] Table 39: Effect on yield of Insecticidal Composition Methoxyfenozide + Spinosad + Novaluron on Cotton Crop

[0163]

[0164] Table 40: Phytotoxic effect of Insecticidal Composition Methoxyfenozide + Spinosad + Novaluron of the present invention on Cotton crop

[0165]

[0166] Table 41: Efficacy of Insecticidal Composition Methoxyfenozide + Spinosad + Lufenuron on Chilli Crop against fruit borer

[0167] Table 42: Efficacy of Insecticidal Composition Methoxyfenozide + Spinosad + Lufenuron on Chilli Crop against Thrips

[0168]

[0169] Table 43: Effect on yield of Insecticidal Composition Methoxyfenozide + Spinosad + Lufenuron on Chilli Crop

[0170] Table 44: Phytotoxic effect of Insecticidal Composition Methoxyfenozide + Spinosad + Lufenuron of the present invention on Chilli crop

[0171]

[0172] Table 45: Efficacy of Insecticidal Composition Methoxyfenozide + Spinosad + Lufenuron on Cotton Crop against Bollworms

[0173] Table 46: Efficacy of Insecticidal Composition Methoxyfenozide + Spinosad + Lufenuron on Cotton Crop against Thrips

[0174] Table 47: Effect on yield of Insecticidal Composition Methoxyfenozide + Spinosad + Lufenuron on Cotton Crop

[0175] Table 48: Phytotoxic effect of Insecticidal Composition Methoxyfenozide + Spinosad + Lufenuron of the present invention on Cotton crop

[0176] It is evident from the above tables 33-48 that the ternary insecticidal compositions of the present invention gave excellent control on crops against tested insects wherein all the prepared ternary compositions found synergistic as compared to the reference products (solo or binary compositions). It has also been found that use of ternary compositions of present invention not only gave better efficiency by using low a.i., content compared to binary and solo composition but also broaden the spectrum of compositions as the solo and binary compositions are not providing sufficient insect control in given duration.

[0177] From the foregoing it will be observed that numerous modifications and variations can be effectuated without departing from the true spirit and scope of the novel concepts of the present invention. It is to be understood that no limitations with respect to the specific embodiments illustrated is intended or should be inferred. It should be understood that all such modifications and improvements have been deleted herein for the sake of conciseness and readability but are properly within the scope of the following claims.

Claims

Claims:

1. A novel insecticidal compositions comprising of Methoxy fenozi de, Spinosad and at least one further active compound selected from the class of chitin synthesis inhibitors such as Novaluron and Lufenuron and agriculturally acceptable excipient.

2. The novel insecticidal compositions as claimed in claim 1, wherein, Methoxyfenozide is present in an amount in the range from 16-60 % w / w; Spinosad is present in an amount in the range from 6-20 % w / w; Novaluron is present in an amount in the range from 7-25 % w / w or Lufenuron is present in an amount in the range from 2-15 % w / w.

3. The novel insecticidal compositions as claimed in claim 1, wherein, Methoxyfenozide is present in an amount in the range from 16-50 % w / w; Spinosad is present in an amount in the range from 7-20 % w / w; Novaluron is present in an amount in the range from 7-25 % w / w.

4. The novel insecticidal compositions as claimed in claim 1, wherein, Methoxyfenozide is present in an amount in the range from 16-60 % w / w; Spinosad is present in an amount in the range from 6-20 % w / w; Lufenuron is present in an amount in the range from 2-15 % w / w.

5. The novel insecticidal compositions as claimed in claim 1, wherein the compositions are formulated as Capsule suspension (CS), Dispersible concentrate (DC), Dustable powder (DP), Dry flowable (DF), Emulsifiable concentrate (EC), Emulsifiable granule (EG), Emulsion water-in-oil (EO), Emulsifiable powder (EP), Emulsion oil-in-water (EW), Granules (GR), Micro-emulsion (ME), Oil-dispersion (OD), Oil miscible flowable concentrate (OF), Oil miscible liquid (OL), Oil dispersible powder (OP), Suspension concentrate (SC), Suspension concentrate for direct application (SD), Suspo-emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Spreading oil (SO), Water soluble powder (SP), Ultra-low volume (ULV) suspension, Ultra-low volume (ULV) liquid, Water dispersible granules (WDG / WG), Wettable powder (WP), a mixed formulation of CS and SC (ZC) or a mixed formulation of CS and SE (ZE), a mixed formulation of CS and EW (ZW).

6. The novel insecticidal compositions as claimed in claim 1, wherein the agriculturally acceptable excipients are selected from the group comprising of dispersing agent, wetting agent, dispersing cum wetting agent, disintegrating agent, defoamer / antifoamer, biocide / preservative, thickener, anti-freeze agent, anti-caking agent, structuring agent, buffering agent, filler and diluent.

7. The novel insecticidal compositions as claimed in claim 6, wherein, a) the dispersing agent, is selected from the group comprising sodium salt of naphthalene sulfonate condensate, polycarboxylate sodium salt, kraft lignin polymer, polymethyl methacrylate-polyethylene glycol graft copolymer, ethoxylated tristyrylphenol, tri styrylphenol phosphate, modified sodium lignosulphonate or a combination thereof, and present in an amount in the range from 0.1 to 20% w / w; b) the wetting agent, is selected from the group comprising polyalkylene oxide block copolymer, alkylaryl sulfonate, sodium alkyl dibutyl naphthalene sulfonate, dicotyl sulfosuccinate, sodium dioctyl sulphosuccinate or a combination thereof, and present in an amount in the range from 0.1-10% vil'W, c) the disintegrating agent, is selected from the group comprising sodium sulfate anhydrous, ammonium sulfate, sodium chloride or a combination thereof and present in an amount in the range from 2-10% w / w; d) the anti-freeze agent, is selected from the group comprising glycerol, propylene glycol, diethylene glycol, monoethylene glycol, urea, sodium chloride, magnesium heptahydrate or a combination thereof and present in an amount in the range from 1 to 10% w / w; e) the antifoamer / defoamer, is selected from the group comprising polydimethylsiloxane antifoam emulsion, powdered silicone antifoam, silicon antifoam emulsion, silicon emulsion, polysiloxane emulsion or a combination thereof and present in an amount in the range from 0.01 to 2% w / w; f) the biocide / preservative, is selected from the group comprising 20% aqueous dipropylene glycol solution of 1, 2-benzisothiazolin-3-one, formaldehyde, 2-methyl-4- isothiazolin-3-one, 5-chloro-2-methyl-4-isothiazolin-3-one or a combination thereof and present in an amount in the range from 0.01 to 1% w / w; g) the thickener, is selected from the group comprising xanthan gum, welan gum, guar gum, polyvinyl alcohol, carboxymethylcellulose, polyvinylpyrrolidone, carboxyvinyl polymer, acrylic polymer, starch derivative, polysaccharide, high purity silica, whitecarbon or a combination thereof and present in an amount in the range from 0.1-5% w / w; h) the anticaking agent is selected from the group comprising precipitated silica, urea formaldehyde resin, organic bentonite, polyolefin particles, fumed silica or a combination thereof, and present in an amount in the range from 0.1 to 10% w / w; i) the structuring agent is selected from the group comprising attapulgite clay, bentonite clay, smectite clay, montmorillonite clay and present in an amount 0.1 to 10% w / w; j) the buffering agent is citric acid and present in an amount 0.01 to 5% w / w; k) the filler, is selected from the group comprising, silica, precipitated silica, sodium bicarbonate, china clay, methyl soyate, sodium sulphate, sodium lignosulphonate, lactose, lactose anhydrous, bentonite clay, kaolin, diatomaceous earth or a combination thereof and present in an amount quantity sufficient (q.s.) to make 100% w / w formulation; l) the diluent is demineralised water and present in an amount quantity sufficient (q.s.) to make 100% w / w formulation.

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